Rank | Gene Set | Z-score |
---|---|---|
1 | regulation of sequestering of triglyceride (GO:0010889) | 8.51567477 |
2 | triglyceride catabolic process (GO:0019433) | 8.38548193 |
3 | white fat cell differentiation (GO:0050872) | 7.65835715 |
4 | acylglycerol catabolic process (GO:0046464) | 7.54748476 |
5 | neutral lipid catabolic process (GO:0046461) | 7.54748476 |
6 | brown fat cell differentiation (GO:0050873) | 7.27168782 |
7 | valine metabolic process (GO:0006573) | 6.90297494 |
8 | biotin metabolic process (GO:0006768) | 6.31367773 |
9 | regulation of cholesterol storage (GO:0010885) | 5.90128399 |
10 | triglyceride biosynthetic process (GO:0019432) | 5.86423760 |
11 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 5.78130073 |
12 | positive regulation of fatty acid oxidation (GO:0046321) | 5.66709074 |
13 | response to dietary excess (GO:0002021) | 5.66564060 |
14 | glycerolipid catabolic process (GO:0046503) | 5.65099389 |
15 | acylglycerol biosynthetic process (GO:0046463) | 5.61216061 |
16 | neutral lipid biosynthetic process (GO:0046460) | 5.61216061 |
17 | fatty acid transmembrane transport (GO:1902001) | 5.58117261 |
18 | negative regulation of macrophage derived foam cell differentiation (GO:0010745) | 5.53469360 |
19 | transcytosis (GO:0045056) | 5.43967242 |
20 | fatty acid beta-oxidation (GO:0006635) | 5.14004609 |
21 | lipid storage (GO:0019915) | 5.11251170 |
22 | ethanol oxidation (GO:0006069) | 4.95301643 |
23 | carnitine shuttle (GO:0006853) | 4.87152574 |
24 | ovulation from ovarian follicle (GO:0001542) | 4.67255190 |
25 | triglyceride metabolic process (GO:0006641) | 4.64752935 |
26 | branched-chain amino acid metabolic process (GO:0009081) | 4.59876685 |
27 | positive regulation of cellular response to insulin stimulus (GO:1900078) | 4.55457293 |
28 | CDP-diacylglycerol metabolic process (GO:0046341) | 4.55060120 |
29 | fatty acid oxidation (GO:0019395) | 4.53219564 |
30 | long-chain fatty-acyl-CoA metabolic process (GO:0035336) | 4.52769346 |
31 | fatty-acyl-CoA metabolic process (GO:0035337) | 4.48376771 |
32 | fatty-acyl-CoA biosynthetic process (GO:0046949) | 4.47939119 |
33 | lipid oxidation (GO:0034440) | 4.44649965 |
34 | protein heterotrimerization (GO:0070208) | 4.44332363 |
35 | branched-chain amino acid catabolic process (GO:0009083) | 4.42410597 |
36 | regulation of fatty acid beta-oxidation (GO:0031998) | 4.41596744 |
37 | plasma lipoprotein particle clearance (GO:0034381) | 4.40910926 |
38 | fatty acid catabolic process (GO:0009062) | 4.40542439 |
39 | acylglycerol metabolic process (GO:0006639) | 4.39061549 |
40 | long-chain fatty-acyl-CoA biosynthetic process (GO:0035338) | 4.37941439 |
41 | polyol transport (GO:0015791) | 4.36089768 |
42 | thioester biosynthetic process (GO:0035384) | 4.34741201 |
43 | acyl-CoA biosynthetic process (GO:0071616) | 4.34741201 |
44 | neutral lipid metabolic process (GO:0006638) | 4.33055015 |
45 | fatty acid homeostasis (GO:0055089) | 4.32346047 |
46 | regulation of fatty acid oxidation (GO:0046320) | 4.32185597 |
47 | negative regulation of protein autophosphorylation (GO:0031953) | 4.30606084 |
48 | alpha-linolenic acid metabolic process (GO:0036109) | 4.27803263 |
49 | positive regulation of fatty acid metabolic process (GO:0045923) | 4.19657113 |
50 | positive regulation of lipoprotein lipase activity (GO:0051006) | 4.17009074 |
51 | positive regulation of triglyceride lipase activity (GO:0061365) | 4.17009074 |
52 | positive regulation of lipid catabolic process (GO:0050996) | 4.16958693 |
53 | positive regulation of insulin receptor signaling pathway (GO:0046628) | 4.13436689 |
54 | primary alcohol metabolic process (GO:0034308) | 4.11849860 |
55 | regulation of macrophage derived foam cell differentiation (GO:0010743) | 4.10613503 |
56 | coenzyme A biosynthetic process (GO:0015937) | 4.10540824 |
57 | negative regulation of tumor necrosis factor-mediated signaling pathway (GO:0010804) | 4.09162172 |
58 | negative regulation of granulocyte differentiation (GO:0030853) | 4.04380022 |
59 | response to phenylpropanoid (GO:0080184) | 4.00671519 |
60 | negative regulation of phagocytosis (GO:0050765) | 3.97739617 |
61 | carnitine transmembrane transport (GO:1902603) | 3.97631126 |
62 | * lipid particle organization (GO:0034389) | 3.91389445 |
63 | cellular response to lithium ion (GO:0071285) | 3.90198268 |
64 | regulation of cAMP-dependent protein kinase activity (GO:2000479) | 3.90123909 |
65 | positive regulation of lipid storage (GO:0010884) | 3.89245098 |
66 | negative regulation of lipid storage (GO:0010888) | 3.87937972 |
67 | glycerol metabolic process (GO:0006071) | 3.87556013 |
68 | positive regulation of glucose import (GO:0046326) | 3.86945135 |
69 | retinol metabolic process (GO:0042572) | 3.86317246 |
70 | ethanol metabolic process (GO:0006067) | 3.81827163 |
71 | positive regulation of glomerulus development (GO:0090193) | 3.79635977 |
72 | pentose-phosphate shunt (GO:0006098) | 3.78743644 |
73 | acetyl-CoA metabolic process (GO:0006084) | 3.75330395 |
74 | regulation of glycogen (starch) synthase activity (GO:2000465) | 3.74842470 |
75 | NADPH regeneration (GO:0006740) | 3.71761350 |
76 | diacylglycerol metabolic process (GO:0046339) | 3.70851063 |
77 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.70354400 |
78 | positive regulation of cholesterol efflux (GO:0010875) | 3.69982120 |
79 | regulation of triglyceride catabolic process (GO:0010896) | 3.67196465 |
80 | tricarboxylic acid metabolic process (GO:0072350) | 3.67120930 |
81 | carnitine transport (GO:0015879) | 3.66382654 |
82 | amino-acid betaine transport (GO:0015838) | 3.66382654 |
83 | positive regulation of glycolytic process (GO:0045821) | 3.65397793 |
84 | phosphatidic acid metabolic process (GO:0046473) | 3.65024516 |
85 | phosphatidic acid biosynthetic process (GO:0006654) | 3.65024516 |
86 | thioester metabolic process (GO:0035383) | 3.63770591 |
87 | acyl-CoA metabolic process (GO:0006637) | 3.63770591 |
88 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 3.63459809 |
89 | positive regulation of sterol transport (GO:0032373) | 3.63293524 |
90 | positive regulation of cholesterol transport (GO:0032376) | 3.63293524 |
91 | oxaloacetate metabolic process (GO:0006107) | 3.61257279 |
92 | NADH metabolic process (GO:0006734) | 3.59696577 |
93 | phospholipid homeostasis (GO:0055091) | 3.58131825 |
94 | complement activation, alternative pathway (GO:0006957) | 3.56969595 |
95 | CDP-diacylglycerol biosynthetic process (GO:0016024) | 3.56252205 |
96 | growth hormone receptor signaling pathway (GO:0060396) | 3.53369211 |
97 | cellular response to epinephrine stimulus (GO:0071872) | 3.51464575 |
98 | negative regulation of macrophage differentiation (GO:0045650) | 3.50769951 |
99 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.49024984 |
100 | cGMP-mediated signaling (GO:0019934) | 3.48569765 |
101 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 3.47218623 |
102 | negative regulation of amino acid transport (GO:0051956) | 3.44963543 |
103 | lipoprotein transport (GO:0042953) | 3.44806717 |
104 | alditol metabolic process (GO:0019400) | 3.43991593 |
105 | L-serine transport (GO:0015825) | 3.41089584 |
106 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 3.40869997 |
107 | negative regulation of gluconeogenesis (GO:0045721) | 3.39141655 |
108 | regulation of lipid storage (GO:0010883) | 3.39045795 |
109 | negative regulation of smooth muscle cell migration (GO:0014912) | 3.38756970 |
110 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.38592579 |
111 | regulation of lipoprotein metabolic process (GO:0050746) | 3.36954076 |
112 | regulation of gonadotropin secretion (GO:0032276) | 3.34002889 |
113 | triglyceride homeostasis (GO:0070328) | 3.33748715 |
114 | acylglycerol homeostasis (GO:0055090) | 3.33748715 |
115 | monocarboxylic acid catabolic process (GO:0072329) | 3.33624586 |
116 | negative regulation of DNA biosynthetic process (GO:2000279) | 3.30754704 |
117 | positive regulation of glucose transport (GO:0010828) | 3.29188448 |
118 | negative regulation of metanephros development (GO:0072217) | 3.28609796 |
119 | regulation of triglyceride metabolic process (GO:0090207) | 3.28230714 |
120 | protein localization to cell surface (GO:0034394) | 3.26438239 |
121 | response to epinephrine (GO:0071871) | 3.26192817 |
122 | intracellular lipid transport (GO:0032365) | 3.25090133 |
123 | cellular lipid catabolic process (GO:0044242) | 3.21968395 |
124 | regulation of cholesterol transport (GO:0032374) | 3.20536568 |
125 | regulation of sterol transport (GO:0032371) | 3.20536568 |
126 | response to hydroperoxide (GO:0033194) | 3.18710336 |
127 | low-density lipoprotein particle clearance (GO:0034383) | 10.1821243 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 6.56647613 |
2 | CLOCK_20551151_ChIP-Seq_293T_Human | 4.77135483 |
3 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 3.13786070 |
4 | * RXR_22158963_ChIP-Seq_LIVER_Mouse | 2.91646381 |
5 | * LXR_22158963_ChIP-Seq_LIVER_Mouse | 2.73403230 |
6 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.68864889 |
7 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 2.59121663 |
8 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.49620980 |
9 | * PPARA_22158963_ChIP-Seq_LIVER_Mouse | 2.46735403 |
10 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 2.32387377 |
11 | * PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 2.11319880 |
12 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 2.06163890 |
13 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.02320424 |
14 | GATA1_22025678_ChIP-Seq_K562_Human | 2.00870232 |
15 | * PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 15.0227330 |
16 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.96202767 |
17 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.91719279 |
18 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.73599665 |
19 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.71660040 |
20 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.67676574 |
21 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.55766173 |
22 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.53596522 |
23 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.44153762 |
24 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.42622538 |
25 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.39038471 |
26 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.37406199 |
27 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.33359440 |
28 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.31179781 |
29 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.30217665 |
30 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.25002226 |
31 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.25002226 |
32 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.24089066 |
33 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 1.12280794 |
34 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 1.11606720 |
35 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.11311916 |
36 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.11075029 |
37 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.10463079 |
38 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.10440676 |
39 | * RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.09607980 |
40 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.09606062 |
41 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.09581311 |
42 | CJUN_26792858_Chip-Seq_BT549_Human | 1.08270489 |
43 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.06714250 |
44 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.06507694 |
45 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.06429926 |
46 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.04916593 |
47 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.04599344 |
48 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.03963880 |
49 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.02581992 |
50 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.01732060 |
51 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 0.99109597 |
52 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 0.98761168 |
53 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.98434258 |
54 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.98257474 |
55 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 0.96550216 |
56 | * NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 0.96454885 |
57 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.96417145 |
58 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 0.96243698 |
59 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 0.95997384 |
60 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 0.94861718 |
61 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 0.94698624 |
62 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.94066608 |
63 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.93625737 |
64 | GATA1_19941826_ChIP-Seq_K562_Human | 0.91948566 |
65 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.90783574 |
66 | CBP_21632823_ChIP-Seq_H3396_Human | 0.89960145 |
67 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 0.89764626 |
68 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.88814259 |
69 | RXR_22108803_ChIP-Seq_LS180_Human | 0.88785119 |
70 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.87901959 |
71 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 0.87446379 |
72 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.85803900 |
73 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 0.85152800 |
74 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.84270990 |
75 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.82148134 |
76 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.81474436 |
77 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.81095425 |
78 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.79667763 |
79 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.79045134 |
80 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 0.77741369 |
81 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 0.77741369 |
82 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 0.77004281 |
83 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 0.76372114 |
84 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.76365660 |
85 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.76055569 |
86 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.75710502 |
87 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.73526939 |
88 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.73468435 |
89 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.72167910 |
90 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.71603337 |
91 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.71193163 |
92 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.71082679 |
93 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.70567321 |
94 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.70529487 |
95 | GATA2_19941826_ChIP-Seq_K562_Human | 0.70433915 |
96 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.69968270 |
97 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.69968270 |
98 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.69933335 |
99 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.68929560 |
100 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 0.68876124 |
101 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.68451377 |
102 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.67680603 |
103 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.67577937 |
104 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 0.67180737 |
105 | SA1_27219007_Chip-Seq_Bcells_Human | 0.66921353 |
106 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.66489972 |
107 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.65999239 |
108 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.65841692 |
109 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.65586816 |
110 | KDM2B_26808549_Chip-Seq_K562_Human | 0.65565849 |
111 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.65388313 |
112 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.65320981 |
113 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 0.65073661 |
114 | SOX3_22085726_ChIP-Seq_MUSCLE_Mouse | 0.64986403 |
115 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.64366717 |
116 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.64345005 |
117 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.63718963 |
118 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.63681817 |
119 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.63085049 |
120 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.62425608 |
121 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 0.62195795 |
122 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.62180174 |
123 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 0.61943049 |
124 | GATA3_20176728_ChIP-ChIP_TSCs_Mouse | 0.60291485 |
125 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 0.59943422 |
126 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 0.59476211 |
127 | * GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.59218164 |
128 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.57014252 |
129 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.56636581 |
130 | ATF3_27146783_Chip-Seq_COLON_Human | 0.56624512 |
131 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.56329400 |
132 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.56140196 |
133 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.56115598 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0005670_abnormal_white_adipose | 8.27952190 |
2 | MP0005666_abnormal_adipose_tissue | 5.62419251 |
3 | MP0004130_abnormal_muscle_cell | 5.01226376 |
4 | MP0004185_abnormal_adipocyte_glucose | 4.89095162 |
5 | MP0008438_abnormal_cutaneous_collagen | 4.50983838 |
6 | MP0005375_adipose_tissue_phenotype | 4.29041711 |
7 | MP0000013_abnormal_adipose_tissue | 3.43627270 |
8 | MP0002876_abnormal_thyroid_physiology | 3.33987278 |
9 | MP0000003_abnormal_adipose_tissue | 3.12643773 |
10 | MP0002837_dystrophic_cardiac_calcinosis | 3.10195756 |
11 | MP0010329_abnormal_lipoprotein_level | 3.02783966 |
12 | MP0005275_abnormal_skin_tensile | 2.88405584 |
13 | MP0003191_abnormal_cellular_cholesterol | 2.76276120 |
14 | * MP0002971_abnormal_brown_adipose | 2.70265016 |
15 | * MP0009115_abnormal_fat_cell | 2.45214695 |
16 | * MP0005334_abnormal_fat_pad | 2.32633438 |
17 | MP0003011_delayed_dark_adaptation | 2.27222908 |
18 | MP0003705_abnormal_hypodermis_morpholog | 2.08414738 |
19 | MP0001661_extended_life_span | 2.07496638 |
20 | * MP0002970_abnormal_white_adipose | 2.00599663 |
21 | * MP0002118_abnormal_lipid_homeostasis | 1.96960999 |
22 | MP0003959_abnormal_lean_body | 1.96342585 |
23 | MP0003868_abnormal_feces_composition | 1.95610071 |
24 | MP0004272_abnormal_basement_membrane | 1.82016650 |
25 | MP0005503_abnormal_tendon_morphology | 1.81821451 |
26 | MP0003690_abnormal_glial_cell | 1.73288171 |
27 | * MP0005535_abnormal_body_temperature | 1.60251589 |
28 | MP0003186_abnormal_redox_activity | 1.59949343 |
29 | MP0003724_increased_susceptibility_to | 1.59587098 |
30 | MP0005365_abnormal_bile_salt | 1.47065552 |
31 | MP0002909_abnormal_adrenal_gland | 1.32073824 |
32 | * MP0005448_abnormal_energy_balance | 1.28748859 |
33 | * MP0005452_abnormal_adipose_tissue | 1.27872373 |
34 | * MP0000609_abnormal_liver_physiology | 1.26967990 |
35 | MP0001881_abnormal_mammary_gland | 1.24300454 |
36 | MP0003828_pulmonary_edema | 1.23827666 |
37 | MP0001501_abnormal_sleep_pattern | 1.23762706 |
38 | MP0009840_abnormal_foam_cell | 1.20414661 |
39 | MP0006138_congestive_heart_failure | 1.19686076 |
40 | * MP0002078_abnormal_glucose_homeostasis | 1.16599788 |
41 | MP0002139_abnormal_hepatobiliary_system | 1.16282097 |
42 | MP0009780_abnormal_chondrocyte_physiolo | 1.14710963 |
43 | MP0003279_aneurysm | 1.09928834 |
44 | MP0002060_abnormal_skin_morphology | 1.09913592 |
45 | MP0002796_impaired_skin_barrier | 1.09565772 |
46 | MP0002254_reproductive_system_inflammat | 1.08523175 |
47 | MP0002166_altered_tumor_susceptibility | 1.05845808 |
48 | MP0001727_abnormal_embryo_implantation | 1.03107637 |
49 | MP0005379_endocrine/exocrine_gland_phen | 1.01080059 |
50 | MP0003045_fibrosis | 1.00345868 |
51 | MP0008775_abnormal_heart_ventricle | 0.98328479 |
52 | MP0000751_myopathy | 0.97042665 |
53 | MP0000750_abnormal_muscle_regeneration | 0.95158564 |
54 | MP0001764_abnormal_homeostasis | 0.94742607 |
55 | MP0000343_altered_response_to | 0.94474149 |
56 | MP0003566_abnormal_cell_adhesion | 0.92504816 |
57 | MP0004019_abnormal_vitamin_homeostasis | 0.90260496 |
58 | MP0003950_abnormal_plasma_membrane | 0.89708434 |
59 | MP0005360_urolithiasis | 0.89408302 |
60 | MP0004147_increased_porphyrin_level | 0.88744095 |
61 | MP0005385_cardiovascular_system_phenoty | 0.87576318 |
62 | MP0001544_abnormal_cardiovascular_syste | 0.87576318 |
63 | MP0001756_abnormal_urination | 0.84328973 |
64 | MP0005620_abnormal_muscle_contractility | 0.83667142 |
65 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.83266839 |
66 | MP0002933_joint_inflammation | 0.83244523 |
67 | MP0005164_abnormal_response_to | 0.82587564 |
68 | MP0002006_tumorigenesis | 0.80255547 |
69 | MP0008961_abnormal_basal_metabolism | 0.79573447 |
70 | MP0002638_abnormal_pupillary_reflex | 0.78962191 |
71 | MP0004087_abnormal_muscle_fiber | 0.78157405 |
72 | MP0000759_abnormal_skeletal_muscle | 0.77987029 |
73 | MP0006036_abnormal_mitochondrial_physio | 0.77910073 |
74 | MP0005319_abnormal_enzyme/_coenzyme | 0.75250621 |
75 | MP0004782_abnormal_surfactant_physiolog | 0.74626833 |
76 | MP0002168_other_aberrant_phenotype | 0.71673613 |
77 | MP0003646_muscle_fatigue | 0.71097273 |
78 | MP0009643_abnormal_urine_homeostasis | 0.69792713 |
79 | MP0000767_abnormal_smooth_muscle | 0.69319490 |
80 | MP0003221_abnormal_cardiomyocyte_apopto | 0.68551651 |
81 | MP0002332_abnormal_exercise_endurance | 0.67328921 |
82 | * MP0003953_abnormal_hormone_level | 0.66217758 |
83 | * MP0003948_abnormal_gas_homeostasis | 0.64341986 |
84 | MP0001177_atelectasis | 0.63920839 |
85 | MP0005332_abnormal_amino_acid | 0.62880155 |
86 | MP0002295_abnormal_pulmonary_circulatio | 0.61055663 |
87 | MP0005058_abnormal_lysosome_morphology | 0.60605153 |
88 | MP0006276_abnormal_autonomic_nervous | 0.60288827 |
89 | MP0001879_abnormal_lymphatic_vessel | 0.60203885 |
90 | MP0004215_abnormal_myocardial_fiber | 0.60069880 |
91 | MP0002108_abnormal_muscle_morphology | 0.59731073 |
92 | MP0005645_abnormal_hypothalamus_physiol | 0.58299925 |
93 | MP0009672_abnormal_birth_weight | 0.58132247 |
94 | MP0002972_abnormal_cardiac_muscle | 0.56632648 |
95 | MP0000249_abnormal_blood_vessel | 0.55755231 |
96 | MP0009763_increased_sensitivity_to | 0.55306131 |
97 | MP0000427_abnormal_hair_cycle | 0.55187847 |
98 | MP0001944_abnormal_pancreas_morphology | 0.54698465 |
99 | MP0003075_altered_response_to | 0.54240822 |
100 | MP0001533_abnormal_skeleton_physiology | 0.53840937 |
101 | MP0003879_abnormal_hair_cell | 0.53654251 |
102 | MP0000749_muscle_degeneration | 0.53225450 |
103 | MP0010368_abnormal_lymphatic_system | 0.52271556 |
104 | MP0000230_abnormal_systemic_arterial | 0.51473000 |
105 | MP0005266_abnormal_metabolism | 0.51440686 |
106 | MP0005165_increased_susceptibility_to | 0.51048893 |
107 | MP0001958_emphysema | 0.51011058 |
108 | MP0005388_respiratory_system_phenotype | 0.50900782 |
109 | MP0002133_abnormal_respiratory_system | 0.50900782 |
110 | MP0005167_abnormal_blood-brain_barrier | 0.49751878 |
111 | MP0000858_altered_metastatic_potential | 0.49399468 |
112 | MP0005330_cardiomyopathy | 0.48773461 |
113 | MP0003448_altered_tumor_morphology | 0.47015880 |
114 | MP0002998_abnormal_bone_remodeling | 0.46994903 |
115 | MP0005647_abnormal_sex_gland | 0.45050814 |
116 | MP0005376_homeostasis/metabolism_phenot | 0.44799784 |
117 | MP0005595_abnormal_vascular_smooth | 0.44396973 |
118 | MP0010630_abnormal_cardiac_muscle | 0.42819685 |
119 | MP0004858_abnormal_nervous_system | 0.42743018 |
120 | MP0000598_abnormal_liver_morphology | 0.42440953 |
121 | MP0005076_abnormal_cell_differentiation | 0.41994129 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Oligomenorrhea (HP:0000876) | 8.79559742 |
2 | * Acanthosis nigricans (HP:0000956) | 6.02531418 |
3 | Hyperglycinuria (HP:0003108) | 5.68046214 |
4 | * Hypertriglyceridemia (HP:0002155) | 5.36159482 |
5 | Abnormality of glycine metabolism (HP:0010895) | 4.67433196 |
6 | Abnormality of serine family amino acid metabolism (HP:0010894) | 4.67433196 |
7 | Insulin-resistant diabetes mellitus (HP:0000831) | 4.65873831 |
8 | Complement deficiency (HP:0004431) | 4.52626560 |
9 | Difficulty running (HP:0009046) | 4.28571226 |
10 | Long foot (HP:0001833) | 3.98110445 |
11 | Myoglobinuria (HP:0002913) | 3.87797119 |
12 | Pigmentary retinal degeneration (HP:0001146) | 3.77677983 |
13 | Increased connective tissue (HP:0009025) | 3.72773426 |
14 | Insulin resistance (HP:0000855) | 3.68946442 |
15 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.59281451 |
16 | Epidermoid cyst (HP:0200040) | 3.56902675 |
17 | Reduced subcutaneous adipose tissue (HP:0003758) | 3.51801149 |
18 | Growth hormone excess (HP:0000845) | 3.50768124 |
19 | Hypoalphalipoproteinemia (HP:0003233) | 3.43236991 |
20 | Hemorrhage of the eye (HP:0011885) | 3.42542658 |
21 | Vertebral compression fractures (HP:0002953) | 3.41522501 |
22 | Hypoglycemic coma (HP:0001325) | 3.38945192 |
23 | Hydroxyprolinuria (HP:0003080) | 3.37347765 |
24 | Abnormality of proline metabolism (HP:0010907) | 3.37347765 |
25 | Subcapsular cataract (HP:0000523) | 3.37195111 |
26 | Bone cyst (HP:0012062) | 3.34061575 |
27 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.29728364 |
28 | Myocardial infarction (HP:0001658) | 3.25903426 |
29 | Ankle contracture (HP:0006466) | 3.23558032 |
30 | Ketoacidosis (HP:0001993) | 3.22739636 |
31 | Abnormality of complement system (HP:0005339) | 3.22174853 |
32 | Increased muscle lipid content (HP:0009058) | 3.19235521 |
33 | Ketosis (HP:0001946) | 3.15352910 |
34 | Increased serum pyruvate (HP:0003542) | 3.15178208 |
35 | Hyperthyroidism (HP:0000836) | 3.14893584 |
36 | Back pain (HP:0003418) | 3.13842549 |
37 | Hyperlipoproteinemia (HP:0010980) | 3.13457057 |
38 | Multiple enchondromatosis (HP:0005701) | 3.10450008 |
39 | Rhabdomyolysis (HP:0003201) | 3.05502362 |
40 | Increased variability in muscle fiber diameter (HP:0003557) | 3.02429610 |
41 | Axonal loss (HP:0003447) | 2.99024108 |
42 | Nausea (HP:0002018) | 2.98599132 |
43 | Large hands (HP:0001176) | 2.94288552 |
44 | Thyroid-stimulating hormone excess (HP:0002925) | 2.91199846 |
45 | Type 1 muscle fiber predominance (HP:0003803) | 2.89988153 |
46 | Broad metatarsal (HP:0001783) | 2.89908474 |
47 | Cerebral aneurysm (HP:0004944) | 2.88778124 |
48 | Xanthomatosis (HP:0000991) | 2.83495887 |
49 | Hyperglycinemia (HP:0002154) | 2.78662476 |
50 | Polycythemia (HP:0001901) | 2.77013076 |
51 | Abnormality of glycolysis (HP:0004366) | 2.76607419 |
52 | Hyperpituitarism (HP:0010514) | 2.72751079 |
53 | Skin nodule (HP:0200036) | 2.70314669 |
54 | Follicular hyperkeratosis (HP:0007502) | 2.69570888 |
55 | Spinal rigidity (HP:0003306) | 2.68977491 |
56 | Colitis (HP:0002583) | 2.68273523 |
57 | Dicarboxylic aciduria (HP:0003215) | 2.66135044 |
58 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.66135044 |
59 | Hyperammonemia (HP:0001987) | 2.64765463 |
60 | Ectopia lentis (HP:0001083) | 2.63974538 |
61 | Pancreatitis (HP:0001733) | 2.62018029 |
62 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.58423575 |
63 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.53899218 |
64 | Hypercholesterolemia (HP:0003124) | 2.45862109 |
65 | Abnormal eating behavior (HP:0100738) | 2.45395282 |
66 | Abnormal cartilage morphology (HP:0002763) | 2.44148206 |
67 | Muscle fiber splitting (HP:0003555) | 2.41125595 |
68 | Prenatal maternal abnormality (HP:0002686) | 2.38575570 |
69 | Facial shape deformation (HP:0011334) | 2.37767637 |
70 | Potter facies (HP:0002009) | 2.37767637 |
71 | Facial diplegia (HP:0001349) | 2.34808080 |
72 | Lipoatrophy (HP:0100578) | 2.34579143 |
73 | Accelerated skeletal maturation (HP:0005616) | 2.34570215 |
74 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.34009348 |
75 | Abnormality of alanine metabolism (HP:0010916) | 2.34009348 |
76 | Hyperalaninemia (HP:0003348) | 2.34009348 |
77 | Slender build (HP:0001533) | 2.32330568 |
78 | Decreased subcutaneous fat (HP:0001002) | 2.27260191 |
79 | Tetraparesis (HP:0002273) | 2.26832357 |
80 | Premature rupture of membranes (HP:0001788) | 2.25336995 |
81 | Neck muscle weakness (HP:0000467) | 2.23938003 |
82 | Lymphangioma (HP:0100764) | 2.19664930 |
83 | Infantile muscular hypotonia (HP:0008947) | 2.19224893 |
84 | Autoimmune thrombocytopenia (HP:0001973) | 2.18993648 |
85 | Amyloidosis (HP:0011034) | 2.18521333 |
86 | Prominent supraorbital ridges (HP:0000336) | 2.16067184 |
87 | Toxemia of pregnancy (HP:0100603) | 2.15828322 |
88 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 2.15588670 |
89 | Hyperglycemia (HP:0003074) | 2.15514983 |
90 | Polar cataract (HP:0010696) | 2.14095319 |
91 | Hyporeflexia of lower limbs (HP:0002600) | 2.13914164 |
92 | Systemic lupus erythematosus (HP:0002725) | 2.12988786 |
93 | Abnormal hemoglobin (HP:0011902) | 2.09580406 |
94 | Striae distensae (HP:0001065) | 2.08072330 |
95 | Cervical subluxation (HP:0003308) | 2.06846142 |
96 | Vascular tortuosity (HP:0004948) | 2.06342400 |
97 | Abnormality of subcutaneous fat tissue (HP:0001001) | 2.06035603 |
98 | Polygenic inheritance (HP:0010982) | 2.05982937 |
99 | Right ventricular cardiomyopathy (HP:0011663) | 2.03557195 |
100 | Turricephaly (HP:0000262) | 2.00968659 |
101 | Easy fatigability (HP:0003388) | 1.99316393 |
102 | Venous abnormality (HP:0002624) | 1.98854930 |
103 | Steatorrhea (HP:0002570) | 1.98540726 |
104 | Abnormality of the periventricular white matter (HP:0002518) | 1.98104189 |
105 | Muscle stiffness (HP:0003552) | 1.97150910 |
106 | Enlarged penis (HP:0000040) | 1.96854338 |
107 | Testicular atrophy (HP:0000029) | 1.96268910 |
108 | Frequent falls (HP:0002359) | 1.93356166 |
109 | Gowers sign (HP:0003391) | 1.93200326 |
110 | Proximal amyotrophy (HP:0007126) | 1.91754618 |
111 | Aortic dissection (HP:0002647) | 1.90257510 |
112 | Hypercortisolism (HP:0001578) | 1.88546728 |
113 | Hepatosplenomegaly (HP:0001433) | 1.87962732 |
114 | Ileus (HP:0002595) | 1.87930308 |
115 | Polyphagia (HP:0002591) | 1.85902626 |
116 | Rectal prolapse (HP:0002035) | 1.85548906 |
117 | Shallow orbits (HP:0000586) | 1.85541871 |
118 | Abnormal glucose tolerance (HP:0001952) | 1.85063495 |
119 | Limb hypertonia (HP:0002509) | 1.84711458 |
120 | Wormian bones (HP:0002645) | 1.82118700 |
121 | Aortic aneurysm (HP:0004942) | 1.80245998 |
122 | Clitoromegaly (HP:0000057) | 1.79504261 |
123 | Gonadotropin excess (HP:0000837) | 1.78866783 |
124 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 1.78573258 |
125 | Esophageal varix (HP:0002040) | 1.77578842 |
126 | Fat malabsorption (HP:0002630) | 1.77452082 |
127 | Hypolipoproteinemia (HP:0010981) | 1.76815014 |
128 | Neonatal onset (HP:0003623) | 1.75402344 |
129 | Pulmonary artery stenosis (HP:0004415) | 1.75051297 |
130 | Neonatal hypoglycemia (HP:0001998) | 1.74863389 |
131 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.73221348 |
132 | Protrusio acetabuli (HP:0003179) | 1.71721836 |
133 | Hyperparathyroidism (HP:0000843) | 1.71678721 |
134 | Resting tremor (HP:0002322) | 1.71174891 |
135 | Impulsivity (HP:0100710) | 1.71044357 |
136 | Opisthotonus (HP:0002179) | 1.70741505 |
137 | Multiple lipomas (HP:0001012) | 1.68481861 |
138 | Increased mean platelet volume (HP:0011877) | 1.67849080 |
139 | Asymmetric septal hypertrophy (HP:0001670) | 1.66626807 |
Rank | Gene Set | Z-score |
---|---|---|
1 | CAMK1D | 6.39772938 |
2 | TRIB3 | 5.71536899 |
3 | CAMK1G | 4.68665521 |
4 | SIK1 | 4.44616766 |
5 | BCKDK | 4.37442223 |
6 | PDK3 | 2.73978339 |
7 | PDK4 | 2.73978339 |
8 | LMTK2 | 2.68815665 |
9 | RIPK1 | 2.67929907 |
10 | TESK1 | 2.61246673 |
11 | MST1R | 2.44346325 |
12 | ERN1 | 2.36921334 |
13 | PRKAA2 | 1.88875902 |
14 | INSRR | 1.78664527 |
15 | FGFR3 | 1.68809908 |
16 | FGFR2 | 1.67854591 |
17 | MAPK4 | 1.67506018 |
18 | PDK2 | 1.61314083 |
19 | GRK5 | 1.60710778 |
20 | FRK | 1.60378664 |
21 | CDK9 | 1.59063729 |
22 | ARAF | 1.51462191 |
23 | PDGFRA | 1.43425865 |
24 | RIPK4 | 1.36940833 |
25 | EPHB2 | 1.33050768 |
26 | CDK6 | 1.28065240 |
27 | PRKD3 | 1.19597475 |
28 | MAP2K1 | 1.14910352 |
29 | EPHA3 | 1.14680804 |
30 | PIK3CA | 1.14155125 |
31 | NLK | 1.13938008 |
32 | MAP3K13 | 1.08386180 |
33 | TGFBR2 | 1.05830414 |
34 | MET | 1.05729106 |
35 | JAK1 | 1.05509597 |
36 | MAP3K6 | 1.02805140 |
37 | TYK2 | 1.01421191 |
38 | LATS1 | 1.00095691 |
39 | PRPF4B | 0.99564844 |
40 | DDR2 | 0.99113378 |
41 | PKN2 | 0.98540033 |
42 | TIE1 | 0.97217692 |
43 | MOS | 0.96491572 |
44 | FGFR4 | 0.95790178 |
45 | PRKAA1 | 0.93902198 |
46 | ADRBK1 | 0.92044252 |
47 | PHKG1 | 0.89323672 |
48 | PHKG2 | 0.89323672 |
49 | PDPK1 | 0.89313633 |
50 | TTN | 0.86411445 |
51 | JAK2 | 0.82982234 |
52 | IRAK3 | 0.82531398 |
53 | NEK9 | 0.81653848 |
54 | PRKCH | 0.80953420 |
55 | FER | 0.80190574 |
56 | KIT | 0.75634785 |
57 | MYLK | 0.72303684 |
58 | MTOR | 0.70271871 |
59 | PDK1 | 0.69541712 |
60 | LATS2 | 0.69261457 |
61 | RET | 0.68968861 |
62 | CDC42BPA | 0.68261418 |
63 | PTK2 | 0.68116007 |
64 | PTK2B | 0.67856987 |
65 | CAMKK2 | 0.66811979 |
66 | IGF1R | 0.66079648 |
67 | PDGFRB | 0.65999854 |
68 | TRPM7 | 0.65842759 |
69 | STK38L | 0.65310800 |
70 | PRKG1 | 0.64552610 |
71 | PRKACG | 0.63587753 |
72 | DAPK3 | 0.61101262 |
73 | ILK | 0.61031790 |
74 | KDR | 0.59619605 |
75 | GSK3A | 0.59611308 |
76 | MAPK11 | 0.59605530 |
77 | MAPK3 | 0.58917915 |
78 | FES | 0.58454583 |
79 | FGFR1 | 0.58315172 |
80 | MAPK7 | 0.55416497 |
81 | PAK2 | 0.54289990 |
82 | BMX | 0.52287531 |
83 | TBK1 | 0.51193187 |
84 | PRKD1 | 0.51114719 |
85 | DAPK2 | 0.51073048 |
86 | CAMK1 | 0.50840198 |
87 | CDK4 | 0.49924715 |
88 | INSR | 0.49894678 |
89 | PKN1 | 0.48235206 |
90 | JAK3 | 0.47607528 |
91 | ZAP70 | 0.46773936 |
92 | CSK | 0.46652672 |
93 | MAP3K1 | 0.45939821 |
94 | PRKG2 | 0.45745460 |
95 | FLT3 | 0.44103660 |
96 | PINK1 | 0.43370869 |
97 | PIM2 | 0.42146357 |
98 | YES1 | 0.41434035 |
99 | RPS6KB1 | 0.40854505 |
100 | STK38 | 0.40714189 |
101 | AKT2 | 0.40035138 |
102 | MAP2K3 | 0.39985143 |
103 | PRKACB | 0.39661788 |
104 | CAMKK1 | 0.38379748 |
105 | ABL2 | 0.38019249 |
106 | SRC | 0.37686416 |
107 | CSF1R | 0.37427292 |
108 | GRK1 | 0.36648674 |
109 | EPHB1 | 0.35844653 |
110 | EIF2AK2 | 0.35496490 |
111 | PRKD2 | 0.35468609 |
112 | EEF2K | 0.35284986 |
113 | MAP2K4 | 0.34145381 |
114 | MARK2 | 0.33932866 |
115 | MAPK12 | 0.32224101 |
116 | ICK | 0.31352203 |
117 | PAK4 | 0.31029414 |
118 | KSR2 | 0.30966494 |
119 | PRKACA | 0.30280671 |
120 | TNK2 | 0.29547740 |
121 | MAP3K11 | 0.29480323 |
122 | STK11 | 0.27420768 |
123 | CDK5 | 0.27022863 |
124 | PTK6 | 0.26876334 |
125 | LRRK2 | 0.24377982 |
126 | ABL1 | 0.23236897 |
127 | IRAK1 | 0.23050613 |
128 | IRAK2 | 0.22912602 |
129 | MAPKAPK3 | 0.22456621 |
130 | TYRO3 | 0.20057386 |
131 | PAK6 | 0.19259596 |
132 | AKT1 | 0.18922794 |
133 | STK3 | 0.18467839 |
134 | MAP3K2 | 0.17769706 |
135 | RPS6KA3 | 0.17232865 |
136 | MAP3K3 | 0.15826011 |
137 | NTRK1 | 0.14322761 |
138 | PRKCZ | 0.14198429 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 4.70869150 |
2 | PPAR signaling pathway_Homo sapiens_hsa03320 | 4.63222971 |
3 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 4.53503251 |
4 | Propanoate metabolism_Homo sapiens_hsa00640 | 4.41060555 |
5 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 3.58321272 |
6 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 3.45490152 |
7 | Fatty acid metabolism_Homo sapiens_hsa01212 | 3.42067257 |
8 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 3.18341268 |
9 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.87554648 |
10 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.72850144 |
11 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 2.25614861 |
12 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.18344444 |
13 | Histidine metabolism_Homo sapiens_hsa00340 | 2.11032804 |
14 | AMPK signaling pathway_Homo sapiens_hsa04152 | 2.06387411 |
15 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 2.03399989 |
16 | Fat digestion and absorption_Homo sapiens_hsa04975 | 2.01327393 |
17 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.87818355 |
18 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.83074019 |
19 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.73715447 |
20 | Carbon metabolism_Homo sapiens_hsa01200 | 1.73445073 |
21 | Peroxisome_Homo sapiens_hsa04146 | 1.58531667 |
22 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.36229163 |
23 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.35006637 |
24 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.31640068 |
25 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.31312290 |
26 | Insulin resistance_Homo sapiens_hsa04931 | 1.29591753 |
27 | Insulin signaling pathway_Homo sapiens_hsa04910 | 1.22549505 |
28 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.22522593 |
29 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.19320805 |
30 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.17961695 |
31 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.11398262 |
32 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.06075989 |
33 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.95807751 |
34 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.95708945 |
35 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.95260813 |
36 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.94209673 |
37 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.91627910 |
38 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.89680963 |
39 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.88626575 |
40 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.88323698 |
41 | Renin secretion_Homo sapiens_hsa04924 | 0.83702848 |
42 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.80625548 |
43 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.79773238 |
44 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.78908105 |
45 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.76327456 |
46 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.68269419 |
47 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.63729233 |
48 | ABC transporters_Homo sapiens_hsa02010 | 0.63663976 |
49 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.63517654 |
50 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.63091947 |
51 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.60955828 |
52 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.58312903 |
53 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.58259473 |
54 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.58172680 |
55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.56652436 |
56 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.56450479 |
57 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.56385726 |
58 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.52608477 |
59 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.50957478 |
60 | Malaria_Homo sapiens_hsa05144 | 0.50448192 |
61 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.47408745 |
62 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.47027738 |
63 | Focal adhesion_Homo sapiens_hsa04510 | 0.46689530 |
64 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.45533821 |
65 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.42667057 |
66 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.42334214 |
67 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.40472226 |
68 | Lysine degradation_Homo sapiens_hsa00310 | 0.40451550 |
69 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.40293824 |
70 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.38825397 |
71 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.37261119 |
72 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.36934566 |
73 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.36688598 |
74 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.35198913 |
75 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.34625954 |
76 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.34386409 |
77 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.28457829 |
78 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.27704230 |
79 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.26228499 |
80 | Mineral absorption_Homo sapiens_hsa04978 | 0.25060925 |
81 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.24891544 |
82 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.23778264 |
83 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.22540821 |
84 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.21322570 |
85 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.20493152 |
86 | Amoebiasis_Homo sapiens_hsa05146 | 0.20402809 |
87 | Lysosome_Homo sapiens_hsa04142 | 0.20070905 |
88 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.19728200 |
89 | Thyroid cancer_Homo sapiens_hsa05216 | 0.17663480 |
90 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.16123341 |
91 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.15224193 |
92 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.14970516 |
93 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.14403632 |
94 | Metabolic pathways_Homo sapiens_hsa01100 | 0.14104661 |
95 | Sulfur relay system_Homo sapiens_hsa04122 | 0.13897943 |
96 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.13430313 |
97 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.12810391 |
98 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.12233089 |
99 | Salivary secretion_Homo sapiens_hsa04970 | 0.11968263 |
100 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.10897587 |
101 | Viral myocarditis_Homo sapiens_hsa05416 | 0.10177454 |
102 | Other glycan degradation_Homo sapiens_hsa00511 | 0.09739106 |
103 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.08529098 |
104 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.08466480 |
105 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.08292952 |
106 | Bile secretion_Homo sapiens_hsa04976 | 0.07863216 |
107 | Platelet activation_Homo sapiens_hsa04611 | 0.07728018 |
108 | Melanoma_Homo sapiens_hsa05218 | 0.07642123 |
109 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.07134405 |
110 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.05781483 |
111 | Cocaine addiction_Homo sapiens_hsa05030 | 0.05634907 |
112 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.04058010 |
113 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.03995499 |
114 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.03903335 |
115 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.03146598 |
116 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.02580206 |
117 | Retinol metabolism_Homo sapiens_hsa00830 | 0.01433772 |
118 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.01143940 |
119 | Galactose metabolism_Homo sapiens_hsa00052 | 0.00390909 |
120 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.00122384 |
121 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | -0.0296168 |
122 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | -0.0145515 |
123 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | -0.0020670 |