CIRBP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1response to pheromone (GO:0019236)4.93875244
2COPI coating of Golgi vesicle (GO:0048205)3.76271564
3Golgi transport vesicle coating (GO:0048200)3.76271564
4pyrimidine nucleobase catabolic process (GO:0006208)3.63624900
5photoreceptor cell maintenance (GO:0045494)3.60237900
6positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.60012386
7intraciliary transport (GO:0042073)3.45512522
8photoreceptor cell development (GO:0042461)3.42533516
9positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.41418796
10negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.41005942
11negative regulation of cell killing (GO:0031342)3.41005942
12retinal rod cell development (GO:0046548)3.39023672
13regulation of rhodopsin mediated signaling pathway (GO:0022400)3.32696797
14synaptic vesicle exocytosis (GO:0016079)3.28807955
15mannose metabolic process (GO:0006013)3.27665878
16rhodopsin mediated signaling pathway (GO:0016056)3.25122642
17regulation of synaptic vesicle exocytosis (GO:2000300)3.21574545
18viral protein processing (GO:0019082)3.16128309
19eye photoreceptor cell development (GO:0042462)3.15644347
20regulation of autophagic vacuole assembly (GO:2000785)3.15029688
21regulation of ARF protein signal transduction (GO:0032012)3.11869366
22postsynaptic membrane organization (GO:0001941)3.09033030
23retinal cone cell development (GO:0046549)3.06680540
24negative regulation of microtubule polymerization (GO:0031115)2.95302199
25negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.95076906
26regulation of synaptic vesicle transport (GO:1902803)2.94731317
27axoneme assembly (GO:0035082)2.94294953
28sequestering of actin monomers (GO:0042989)2.93444178
29synaptic vesicle maturation (GO:0016188)2.92855019
30photoreceptor cell differentiation (GO:0046530)2.92412245
31eye photoreceptor cell differentiation (GO:0001754)2.92412245
32adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191)2.92243800
33GMP metabolic process (GO:0046037)2.85615965
34potassium ion export (GO:0071435)2.81505449
35positive thymic T cell selection (GO:0045059)2.80094234
36regulation of short-term neuronal synaptic plasticity (GO:0048172)2.79751499
37ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:0043162.76100666
38detection of calcium ion (GO:0005513)2.75942280
39regulation of synapse structural plasticity (GO:0051823)2.74732812
40activation of protein kinase A activity (GO:0034199)2.73913899
41antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.73598047
42regulation of ARF GTPase activity (GO:0032312)2.70306942
43histone H2A acetylation (GO:0043968)2.69558558
44regulation of inhibitory postsynaptic membrane potential (GO:0060080)2.68885542
45protein localization to synapse (GO:0035418)2.68658792
46nonmotile primary cilium assembly (GO:0035058)2.68256506
47melanosome transport (GO:0032402)2.68107311
48cerebellar granule cell differentiation (GO:0021707)2.65240426
49sensory perception of taste (GO:0050909)2.65189090
50synaptic vesicle docking involved in exocytosis (GO:0016081)2.65146632
51establishment of mitochondrion localization (GO:0051654)2.64004192
52protein localization to cilium (GO:0061512)2.64001215
53cilium or flagellum-dependent cell motility (GO:0001539)2.62706684
54neuron cell-cell adhesion (GO:0007158)2.62369571
55protein polyglutamylation (GO:0018095)2.62140616
56antigen processing and presentation of endogenous antigen (GO:0019883)2.62121904
57positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.61414500
58cerebellum development (GO:0021549)2.60808555
59spinal cord development (GO:0021510)2.60363117
60lactate metabolic process (GO:0006089)2.59345379
61dopamine receptor signaling pathway (GO:0007212)2.57746415
62regulation of defense response to virus by virus (GO:0050690)2.57682234
63axonemal dynein complex assembly (GO:0070286)2.57080746
64antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.56768514
65thymic T cell selection (GO:0045061)2.56362795
66negative regulation of glycoprotein biosynthetic process (GO:0010561)2.56257291
67locomotory exploration behavior (GO:0035641)2.56248744
68positive regulation of insulin secretion (GO:0032024)2.55993690
69regulation of alternative mRNA splicing, via spliceosome (GO:0000381)2.55264828
70cellular response to catecholamine stimulus (GO:0071870)2.54832308
71cellular response to monoamine stimulus (GO:0071868)2.54832308
72positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.54191953
73pigment granule transport (GO:0051904)2.53105876
74piRNA metabolic process (GO:0034587)2.53042010
75glandular epithelial cell differentiation (GO:0002067)2.52422986
76glial cell proliferation (GO:0014009)2.50644510
77regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act2.47939697
78response to muramyl dipeptide (GO:0032495)2.47629099
79neuronal ion channel clustering (GO:0045161)2.46994921
80membrane repolarization during cardiac muscle cell action potential (GO:0086013)2.45964035
81melanosome localization (GO:0032400)2.45518389
82layer formation in cerebral cortex (GO:0021819)2.45190928
83antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.44868818
84cell migration in hindbrain (GO:0021535)2.44482019
85positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.43369286
86ionotropic glutamate receptor signaling pathway (GO:0035235)2.42702649
87establishment of melanosome localization (GO:0032401)2.41640223
88histone H4-K5 acetylation (GO:0043981)2.40820078
89histone H4-K8 acetylation (GO:0043982)2.40820078
90regulation of respiratory system process (GO:0044065)2.40449059
91sodium ion export (GO:0071436)2.40276090
92camera-type eye morphogenesis (GO:0048593)2.38716348
93cellular response to glucagon stimulus (GO:0071377)2.38448198
94regulation of cilium movement (GO:0003352)2.37462456
95cell communication by electrical coupling (GO:0010644)2.37316508
96hippocampus development (GO:0021766)2.36197679
97response to misfolded protein (GO:0051788)2.35671891
98negative regulation of type 2 immune response (GO:0002829)2.35118921
99detection of light stimulus involved in visual perception (GO:0050908)2.35002510
100detection of light stimulus involved in sensory perception (GO:0050962)2.35002510
101positive regulation of synapse maturation (GO:0090129)2.34699039
102positive regulation of synaptic transmission, GABAergic (GO:0032230)2.34513294
103positive regulation of gastrulation (GO:2000543)2.34430168
104positive regulation of Rap GTPase activity (GO:0032854)2.34044021
105pigment granule localization (GO:0051875)2.33333338
106peptidyl-tyrosine autophosphorylation (GO:0038083)2.32670688
107membrane repolarization during action potential (GO:0086011)2.32146104
108negative regulation of cytosolic calcium ion concentration (GO:0051481)2.31112013
109regulation of microtubule-based movement (GO:0060632)2.30820566
110endothelial cell chemotaxis (GO:0035767)2.29649242
111regulation of vacuole organization (GO:0044088)2.29075912
112retina development in camera-type eye (GO:0060041)2.28817143
113establishment of pigment granule localization (GO:0051905)2.28523721
114regulation of beta-amyloid formation (GO:1902003)2.27963007
115regulation of insulin secretion (GO:0050796)2.27486763
116regulation of type B pancreatic cell apoptotic process (GO:2000674)2.26945800
117establishment of mitochondrion localization, microtubule-mediated (GO:0034643)2.26024847
118mitochondrion transport along microtubule (GO:0047497)2.26024847
119endocrine pancreas development (GO:0031018)2.25157992
120regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.24770364
121histone H3 deacetylation (GO:0070932)2.24726356
122positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.24725103
123membrane repolarization (GO:0086009)2.24461855
124positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.24203330
125adenosine receptor signaling pathway (GO:0001973)2.24083221
126central nervous system projection neuron axonogenesis (GO:0021952)2.23557412
127cell-cell junction maintenance (GO:0045217)2.22481202
128neuron fate specification (GO:0048665)2.22132188
129negative regulation of myotube differentiation (GO:0010832)2.21700805
130neuromuscular synaptic transmission (GO:0007274)2.21510646
131positive regulation of gamma-delta T cell activation (GO:0046645)2.21416636
132regulation of membrane repolarization (GO:0060306)2.21240866
133neuron projection regeneration (GO:0031102)2.21006633
134innervation (GO:0060384)2.20848108
135positive regulation of amino acid transport (GO:0051957)2.19952279
136motile cilium assembly (GO:0044458)2.19673790
137hair cell differentiation (GO:0035315)2.19413857
138negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.19323272
139regulation of vesicle fusion (GO:0031338)2.19039802
140cellular potassium ion homeostasis (GO:0030007)2.18436958
141negative regulation of catenin import into nucleus (GO:0035414)2.18122825
142exploration behavior (GO:0035640)2.17977041
143regulation of chromatin binding (GO:0035561)2.17942992
144positive T cell selection (GO:0043368)2.17542745
145regulation of male gonad development (GO:2000018)2.16433138
146nucleobase catabolic process (GO:0046113)2.16245407
147dendritic spine morphogenesis (GO:0060997)2.16072101
148sensory perception of chemical stimulus (GO:0007606)2.15704397
149regulation of gamma-delta T cell differentiation (GO:0045586)2.15526064
150negative regulation of erythrocyte differentiation (GO:0045647)2.15189550
151retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.15056332
152respiratory system process (GO:0003016)2.14421318
153regulation of amyloid precursor protein catabolic process (GO:1902991)2.12847137
154T cell selection (GO:0045058)2.11208192
155activated T cell proliferation (GO:0050798)2.10351438
156glutamate secretion (GO:0014047)2.09690413
157positive regulation of protein kinase C signaling (GO:0090037)2.08419205
158negative regulation of lymphocyte mediated immunity (GO:0002707)2.07932706
159cellular response to prostaglandin stimulus (GO:0071379)2.07602460
160germinal center formation (GO:0002467)2.05253879
161histone H3-K9 demethylation (GO:0033169)2.04811501
162neuromuscular process controlling balance (GO:0050885)2.04072670
163negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.03786725
164regulation of Rap GTPase activity (GO:0032317)2.02557837
165histone H4 deacetylation (GO:0070933)2.02523742
166negative regulation of leukocyte mediated immunity (GO:0002704)2.02168491
167vocalization behavior (GO:0071625)2.01899362
168response to monoamine (GO:0071867)2.00674923
169response to catecholamine (GO:0071869)2.00674923
170regulation of gamma-delta T cell activation (GO:0046643)2.00170076
171negative regulation of Ras protein signal transduction (GO:0046580)2.00005110
172positive regulation of synaptic transmission, glutamatergic (GO:0051968)1.99146090
173semaphorin-plexin signaling pathway (GO:0071526)1.98814322
174regulation of glutamate receptor signaling pathway (GO:1900449)1.98770910
175negative thymic T cell selection (GO:0045060)1.98743538
176negative regulation of glycoprotein metabolic process (GO:1903019)1.98256148
177peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)1.97786075
178negative regulation of granulocyte differentiation (GO:0030853)1.97056559
179response to prostaglandin E (GO:0034695)1.96712727
180cAMP biosynthetic process (GO:0006171)1.95849862
181negative regulation of small GTPase mediated signal transduction (GO:0051058)1.94422550

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.94867542
2CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons4.15761380
3THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse3.00349602
4TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.95019433
5* KDM2B_26808549_Chip-Seq_SUP-B15_Human2.79900380
6DMRT1_21621532_ChIP-ChIP_FETAL_Ovary2.64871952
7NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.61053312
8* VDR_21846776_ChIP-Seq_THP-1_Human2.57125760
9MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.41552278
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.32003637
11* KDM2B_26808549_Chip-Seq_DND41_Human2.26712227
12EZH2_27294783_Chip-Seq_ESCs_Mouse2.25565522
13IKZF1_21737484_ChIP-ChIP_HCT116_Human2.25061822
14SUZ12_27294783_Chip-Seq_ESCs_Mouse2.23329767
15JARID2_20075857_ChIP-Seq_MESCs_Mouse2.18100675
16ERG_21242973_ChIP-ChIP_JURKAT_Human2.14886672
17REST_21632747_ChIP-Seq_MESCs_Mouse2.13681011
18REST_18959480_ChIP-ChIP_MESCs_Mouse2.11070738
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.08564989
20TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse2.07105123
21* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.06610109
22* TCF7_22412390_ChIP-Seq_EML_Mouse1.95611456
23JARID2_20064375_ChIP-Seq_MESCs_Mouse1.91898452
24RNF2_27304074_Chip-Seq_ESCs_Mouse1.91350847
25SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.87599656
26SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.86103041
27* CIITA_25753668_ChIP-Seq_RAJI_Human1.79750371
28* OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.74171901
29RARG_19884340_ChIP-ChIP_MEFs_Mouse1.73362636
30CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.72088482
31* KDM2B_26808549_Chip-Seq_JURKAT_Human1.71981913
32EZH2_18974828_ChIP-Seq_MESCs_Mouse1.71147700
33RNF2_18974828_ChIP-Seq_MESCs_Mouse1.71147700
34CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.68423421
35BMI1_23680149_ChIP-Seq_NPCS_Mouse1.68254753
36SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.68055962
37ELK3_25401928_ChIP-Seq_HUVEC_Human1.67344406
38SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.66623314
39* SA1_27219007_Chip-Seq_ERYTHROID_Human1.63696807
40VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.60808761
41DROSHA_22980978_ChIP-Seq_HELA_Human1.59035098
42SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.58590163
43* RARB_27405468_Chip-Seq_BRAIN_Mouse1.56629535
44* ZFP281_18757296_ChIP-ChIP_E14_Mouse1.56094090
45* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.54878327
46* RACK7_27058665_Chip-Seq_MCF-7_Human1.53872812
47RNF2_27304074_Chip-Seq_NSC_Mouse1.53758424
48DNAJC2_21179169_ChIP-ChIP_NT2_Human1.52847547
49CREB1_26743006_Chip-Seq_LNCaP_Human1.50389839
50* CTCF_27219007_Chip-Seq_ERYTHROID_Human1.50220250
51MTF2_20144788_ChIP-Seq_MESCs_Mouse1.47447605
52* VDR_24763502_ChIP-Seq_THP-1_Human1.47046463
53PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.45829657
54WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.45742080
55EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44601945
56TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.44543161
57EED_16625203_ChIP-ChIP_MESCs_Mouse1.44503684
58* MAF_26560356_Chip-Seq_TH2_Human1.44207891
59CBX2_27304074_Chip-Seq_ESCs_Mouse1.43018212
60MAF_26560356_Chip-Seq_TH1_Human1.42359699
61UTX_26944678_Chip-Seq_JUKART_Human1.41816031
62* SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.39056032
63SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.38996887
64BP1_19119308_ChIP-ChIP_Hs578T_Human1.37087071
65TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36248037
66GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.34874354
67* SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.34653032
68CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.31324480
69PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.30638608
70CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.30416808
71GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.28811828
72ESR2_21235772_ChIP-Seq_MCF-7_Human1.28359308
73ELF1_20517297_ChIP-Seq_JURKAT_Human1.27041099
74SRY_22984422_ChIP-ChIP_TESTIS_Rat1.26048105
75* MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human1.24855129
76STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.23783177
77GATA1_19941827_ChIP-Seq_MEL_Mouse1.23697663
78RING1B_27294783_Chip-Seq_ESCs_Mouse1.23092198
79NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.19028459
80BCOR_27268052_Chip-Seq_Bcells_Human1.18712964
81THAP11_20581084_ChIP-Seq_MESCs_Mouse1.17467867
82SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.16170874
83UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.13182544
84GBX2_23144817_ChIP-Seq_PC3_Human1.12893491
85SA1_27219007_Chip-Seq_Bcells_Human1.12073678
86* SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11088784
87* RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.10548387
88NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.10458746
89* CTCF_27219007_Chip-Seq_Bcells_Human1.10242404
90CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.08063709
91* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.07879933
92PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.07300869
93TP63_19390658_ChIP-ChIP_HaCaT_Human1.07286237
94RUNX1_27514584_Chip-Seq_MCF-7_Human1.06155695
95IGF1R_20145208_ChIP-Seq_DFB_Human1.06142457
96RBPJ_22232070_ChIP-Seq_NCS_Mouse1.05475788
97RUNX1_22412390_ChIP-Seq_EML_Mouse1.05364158
98SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.04941525
99ELF1_17652178_ChIP-ChIP_JURKAT_Human1.04374207
100* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.04311098
101RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.04302558
102* TP63_22573176_ChIP-Seq_HFKS_Human1.03933906
103* MYC_22102868_ChIP-Seq_BL_Human1.03528045
104PHF8_20622854_ChIP-Seq_HELA_Human1.03329676
105* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.02548659
106OCT4_19829295_ChIP-Seq_ESCs_Human1.02013394
107RING1B_27294783_Chip-Seq_NPCs_Mouse1.01821609
108ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.01783181
109SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.00414049
110CTCF_18555785_ChIP-Seq_MESCs_Mouse0.99958149
111NFIB_24661679_ChIP-Seq_LUNG_Mouse0.98823170
112* MEIS1_20887958_ChIP-Seq_HPC-7_Mouse0.98012589
113* RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.97046057
114ZNF274_21170338_ChIP-Seq_K562_Hela0.96969900
115E2F1_20622854_ChIP-Seq_HELA_Human0.96499861
116* CTCF_21964334_ChIP-Seq_BJAB-B_Human0.95571078
117FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.95417132
118* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.94337858
119RUNX1_26923725_Chip-Seq_HPCs_Mouse0.94146240
120TET1_21490601_ChIP-Seq_MESCs_Mouse0.93366490
121CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.92073983
122TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91285995
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.91285995
124TET1_21451524_ChIP-Seq_MESCs_Mouse0.91237949
125RNF2_16625203_ChIP-ChIP_MESCs_Mouse0.90434411
126SMC4_20622854_ChIP-Seq_HELA_Human0.89855186
127EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.88848321
128STAT6_21828071_ChIP-Seq_BEAS2B_Human0.86522030
129PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.86471364
130* LXR_22292898_ChIP-Seq_THP-1_Human0.86019079
131* REST_19997604_ChIP-ChIP_NEURONS_Mouse0.86007384
132YY1_22570637_ChIP-Seq_MALME-3M_Human0.85956925
133* KDM2B_26808549_Chip-Seq_K562_Human0.85424221
134PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.84838976
135YY1_21170310_ChIP-Seq_MESCs_Mouse0.82469236
136ELK4_26923725_Chip-Seq_MESODERM_Mouse0.81497302
137P68_20966046_ChIP-Seq_HELA_Human0.80471364
138* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.80218952
139TP53_20018659_ChIP-ChIP_R1E_Mouse0.80042326
140E2F1_17053090_ChIP-ChIP_MCF-7_Human0.79393152
141BCL6_27268052_Chip-Seq_Bcells_Human0.78865505
142SOX3_22085726_ChIP-Seq_NPCs_Mouse0.78126982
143LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.78107127
144SETDB1_19884255_ChIP-Seq_MESCs_Mouse0.77808305
145SMAD3_21741376_ChIP-Seq_ESCs_Human0.76836697
146WDR5_24793694_ChIP-Seq_LNCAP_Human0.76256057
147FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human0.74689020
148E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.74588217
149POU3F1_26484290_ChIP-Seq_ESCss_Mouse0.74367830
150ZFP281_27345836_Chip-Seq_ESCs_Mouse0.74282519

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001984_abnormal_olfaction3.41466910
2MP0006072_abnormal_retinal_apoptosis3.25431300
3MP0002638_abnormal_pupillary_reflex3.13226543
4MP0002909_abnormal_adrenal_gland2.71666023
5MP0005551_abnormal_eye_electrophysiolog2.70075477
6MP0003329_amyloid_beta_deposits2.63253978
7MP0008789_abnormal_olfactory_epithelium2.60396929
8MP0005423_abnormal_somatic_nervous2.58863971
9MP0005645_abnormal_hypothalamus_physiol2.56967796
10MP0002653_abnormal_ependyma_morphology2.47878995
11MP0010386_abnormal_urinary_bladder2.46632927
12MP0005253_abnormal_eye_physiology2.41768348
13MP0006292_abnormal_olfactory_placode2.41013476
14MP0005499_abnormal_olfactory_system2.34334710
15MP0005394_taste/olfaction_phenotype2.34334710
16MP0002822_catalepsy2.33746201
17MP0003122_maternal_imprinting2.33385851
18MP0006276_abnormal_autonomic_nervous2.28851446
19MP0003880_abnormal_central_pattern2.26641717
20MP0001502_abnormal_circadian_rhythm2.19478556
21MP0003303_peritoneal_inflammation2.15373827
22MP0003787_abnormal_imprinting2.13870083
23MP0005646_abnormal_pituitary_gland2.13089755
24MP0000013_abnormal_adipose_tissue2.12746440
25MP0003690_abnormal_glial_cell2.07291269
26MP0004859_abnormal_synaptic_plasticity2.05112545
27MP0009278_abnormal_bone_marrow2.02469074
28MP0003436_decreased_susceptibility_to1.94354017
29MP0008995_early_reproductive_senescence1.91063218
30MP0009379_abnormal_foot_pigmentation1.91048716
31MP0004130_abnormal_muscle_cell1.88635882
32MP0000631_abnormal_neuroendocrine_gland1.87675197
33MP0005058_abnormal_lysosome_morphology1.87010761
34MP0001958_emphysema1.86470534
35MP0001986_abnormal_taste_sensitivity1.84256581
36MP0000678_abnormal_parathyroid_gland1.80802539
37MP0002184_abnormal_innervation1.73090898
38MP0003635_abnormal_synaptic_transmissio1.69313203
39MP0008877_abnormal_DNA_methylation1.61010853
40MP0004270_analgesia1.60485065
41MP0003879_abnormal_hair_cell1.57179491
42MP0002557_abnormal_social/conspecific_i1.54432867
43MP0003172_abnormal_lysosome_physiology1.54210194
44MP0000778_abnormal_nervous_system1.50602992
45MP0003011_delayed_dark_adaptation1.48669361
46MP0002063_abnormal_learning/memory/cond1.48615596
47MP0002751_abnormal_autonomic_nervous1.47444825
48MP0002234_abnormal_pharynx_morphology1.46220919
49MP0000604_amyloidosis1.44363776
50MP0002734_abnormal_mechanical_nocicepti1.40038233
51MP0009780_abnormal_chondrocyte_physiolo1.38066858
52MP0001944_abnormal_pancreas_morphology1.37890885
53MP0003183_abnormal_peptide_metabolism1.37627513
54MP0000751_myopathy1.37607030
55MP0003724_increased_susceptibility_to1.34929572
56MP0008569_lethality_at_weaning1.32692886
57MP0002882_abnormal_neuron_morphology1.30701510
58MP0003763_abnormal_thymus_physiology1.30583554
59MP0002572_abnormal_emotion/affect_behav1.26572629
60MP0002837_dystrophic_cardiac_calcinosis1.26464689
61MP0002272_abnormal_nervous_system1.24774670
62MP0002249_abnormal_larynx_morphology1.24267454
63MP0002693_abnormal_pancreas_physiology1.23827214
64MP0002938_white_spotting1.22447898
65MP0005409_darkened_coat_color1.22080886
66MP0004885_abnormal_endolymph1.19907190
67MP0003121_genomic_imprinting1.19368111
68MP0008961_abnormal_basal_metabolism1.18549334
69MP0000955_abnormal_spinal_cord1.18125097
70MP0002752_abnormal_somatic_nervous1.18080240
71MP0003634_abnormal_glial_cell1.17492588
72MP0004811_abnormal_neuron_physiology1.15634811
73MP0002735_abnormal_chemical_nociception1.14983685
74MP0005387_immune_system_phenotype1.12080729
75MP0001790_abnormal_immune_system1.12080729
76MP0001849_ear_inflammation1.11474166
77MP0002067_abnormal_sensory_capabilities1.10565375
78MP0005391_vision/eye_phenotype1.10497563
79MP0005195_abnormal_posterior_eye1.07898028
80MP0005666_abnormal_adipose_tissue1.04430564
81MP0000049_abnormal_middle_ear1.03552879
82MP0005503_abnormal_tendon_morphology1.03433645
83MP0001970_abnormal_pain_threshold1.03183881
84MP0005025_abnormal_response_to1.03096628
85MP0002733_abnormal_thermal_nociception1.02978704
86MP0000920_abnormal_myelination1.01473365
87MP0003279_aneurysm1.01415517
88MP0000747_muscle_weakness1.01144440
89MP0004043_abnormal_pH_regulation1.00849484
90MP0001270_distended_abdomen0.99695885
91MP0005377_hearing/vestibular/ear_phenot0.98992117
92MP0003878_abnormal_ear_physiology0.98992117
93MP0001968_abnormal_touch/_nociception0.98668031
94MP0003866_abnormal_defecation0.97276636
95MP0002933_joint_inflammation0.96572178
96MP0000534_abnormal_ureter_morphology0.96524372
97MP0009745_abnormal_behavioral_response0.95687425
98MP0004947_skin_inflammation0.94415053
99MP0001188_hyperpigmentation0.94374972
100MP0003705_abnormal_hypodermis_morpholog0.94229548
101MP0003942_abnormal_urinary_system0.94110660
102MP0002229_neurodegeneration0.93882823
103MP0003283_abnormal_digestive_organ0.92889652
104MP0001800_abnormal_humoral_immune0.92747086
105MP0005375_adipose_tissue_phenotype0.92492713
106MP0005535_abnormal_body_temperature0.90266594
107MP0000026_abnormal_inner_ear0.90234651
108MP0001485_abnormal_pinna_reflex0.89514002
109MP0002064_seizures0.89250842
110MP0008260_abnormal_autophagy0.88926319
111MP0001486_abnormal_startle_reflex0.88038328
112MP0009384_cardiac_valve_regurgitation0.87843807
113MP0001501_abnormal_sleep_pattern0.87420663
114MP0002152_abnormal_brain_morphology0.87251368
115MP0000003_abnormal_adipose_tissue0.86628655
116MP0001348_abnormal_lacrimal_gland0.85799282
117MP0000681_abnormal_thyroid_gland0.84682896
118MP0005000_abnormal_immune_tolerance0.84356625
119MP0001533_abnormal_skeleton_physiology0.82902531
120MP0004510_myositis0.82848139
121MP0004145_abnormal_muscle_electrophysio0.82781965
122MP0001963_abnormal_hearing_physiology0.82711976
123MP0003091_abnormal_cell_migration0.82680997
124MP0001324_abnormal_eye_pigmentation0.82504900
125MP0005671_abnormal_response_to0.82475007
126MP0002009_preneoplasia0.81686648
127MP0005187_abnormal_penis_morphology0.81240260
128MP0002998_abnormal_bone_remodeling0.80881423
129MP0002723_abnormal_immune_serum0.80332962
130MP0003119_abnormal_digestive_system0.79676296
131MP0001440_abnormal_grooming_behavior0.79475715
132MP0002419_abnormal_innate_immunity0.79231527
133MP0008874_decreased_physiological_sensi0.79175850
134MP0002132_abnormal_respiratory_system0.78597709
135MP0002420_abnormal_adaptive_immunity0.77626966
136MP0002133_abnormal_respiratory_system0.76780301
137MP0005388_respiratory_system_phenotype0.76780301
138MP0001819_abnormal_immune_cell0.75811460
139MP0002066_abnormal_motor_capabilities/c0.75772303
140MP0003300_gastrointestinal_ulcer0.75365661
141MP0003698_abnormal_male_reproductive0.75230064
142MP0003632_abnormal_nervous_system0.75006865
143MP0004085_abnormal_heartbeat0.73134247
144MP0008058_abnormal_DNA_repair0.73085742
145MP0000613_abnormal_salivary_gland0.71966860
146MP0000538_abnormal_urinary_bladder0.71785102
147MP0005379_endocrine/exocrine_gland_phen0.71428128
148MP0004858_abnormal_nervous_system0.71352533
149MP0003315_abnormal_perineum_morphology0.70771849
150MP0002069_abnormal_eating/drinking_beha0.70379576
151MP0002928_abnormal_bile_duct0.69702087
152MP0002210_abnormal_sex_determination0.69284633
153MP0003861_abnormal_nervous_system0.69122055
154MP0002102_abnormal_ear_morphology0.68690287
155MP0001529_abnormal_vocalization0.67551319
156MP0004924_abnormal_behavior0.67516717

Predicted human phenotypes

RankGene SetZ-score
1Abnormal rod and cone electroretinograms (HP:0008323)5.48713513
2Absent rod-and cone-mediated responses on ERG (HP:0007688)5.41269985
3Bony spicule pigmentary retinopathy (HP:0007737)4.71194942
4Congenital stationary night blindness (HP:0007642)4.52174425
5Obstructive sleep apnea (HP:0002870)4.22512204
6Elevated circulating parathyroid hormone (PTH) level (HP:0003165)3.78020070
7Turricephaly (HP:0000262)3.69431135
8Papilledema (HP:0001085)3.47651660
9Neurofibrillary tangles (HP:0002185)3.31599753
10Central scotoma (HP:0000603)3.28761618
11Gait imbalance (HP:0002141)3.22529078
12Eczematoid dermatitis (HP:0000976)3.20983946
13Nasal polyposis (HP:0100582)3.17571153
14Attenuation of retinal blood vessels (HP:0007843)3.03416924
15Medial flaring of the eyebrow (HP:0010747)2.98740693
16Agitation (HP:0000713)2.91607502
17Congenital primary aphakia (HP:0007707)2.91183970
18Abnormality of the nasal mucosa (HP:0000433)2.90342645
19Nephrogenic diabetes insipidus (HP:0009806)2.88785748
20Type II diabetes mellitus (HP:0005978)2.88612850
21Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.86442117
22Supranuclear gaze palsy (HP:0000605)2.85901922
23Annular pancreas (HP:0001734)2.85510604
24Visual hallucinations (HP:0002367)2.84269477
25True hermaphroditism (HP:0010459)2.82261983
26Interstitial pulmonary disease (HP:0006530)2.78587125
27Pendular nystagmus (HP:0012043)2.72220720
28Atelectasis (HP:0100750)2.72215887
29Abnormal respiratory motile cilium morphology (HP:0005938)2.71009706
30Abnormal respiratory epithelium morphology (HP:0012253)2.71009706
31Pheochromocytoma (HP:0002666)2.66297523
32Failure to thrive in infancy (HP:0001531)2.62617693
33Severe visual impairment (HP:0001141)2.61651636
34Decreased circulating renin level (HP:0003351)2.61207677
35Abnormal hair whorl (HP:0010721)2.58319419
36Thin bony cortex (HP:0002753)2.57256694
37Abnormality of calcium-phosphate metabolism (HP:0100530)2.53683711
38Hypothermia (HP:0002045)2.51957224
39Exercise-induced myalgia (HP:0003738)2.47656583
40Decreased central vision (HP:0007663)2.46433547
41Dynein arm defect of respiratory motile cilia (HP:0012255)2.45974103
42Absent/shortened dynein arms (HP:0200106)2.45974103
43Abnormality of macular pigmentation (HP:0008002)2.45514919
44Constricted visual fields (HP:0001133)2.45421851
45Neuroendocrine neoplasm (HP:0100634)2.44759541
46Fetal akinesia sequence (HP:0001989)2.42691009
47Scotoma (HP:0000575)2.40515725
48Abnormality of midbrain morphology (HP:0002418)2.36822227
49Molar tooth sign on MRI (HP:0002419)2.36822227
50Abnormal respiratory motile cilium physiology (HP:0012261)2.35465175
51Sleep apnea (HP:0010535)2.32460715
52Neuronal loss in central nervous system (HP:0002529)2.32405956
53Asymmetric septal hypertrophy (HP:0001670)2.32069153
54Retinitis pigmentosa (HP:0000510)2.31865441
55Neoplasm of the heart (HP:0100544)2.30383041
56Cerebral inclusion bodies (HP:0100314)2.30007258
57Abnormal ciliary motility (HP:0012262)2.29094744
58Vaginal atresia (HP:0000148)2.27835996
59Abolished electroretinogram (ERG) (HP:0000550)2.26104132
60Prominent metopic ridge (HP:0005487)2.25041359
61Myopathic facies (HP:0002058)2.24624557
62Chorioretinal atrophy (HP:0000533)2.24579700
63Recurrent sinusitis (HP:0011108)2.24006578
64Increased IgE level (HP:0003212)2.20933078
65Abnormality of the metopic suture (HP:0005556)2.20771663
66Dysostosis multiplex (HP:0000943)2.19864211
67Increased corneal curvature (HP:0100692)2.18482168
68Keratoconus (HP:0000563)2.18482168
69Pancreatic fibrosis (HP:0100732)2.18168099
70Limb dystonia (HP:0002451)2.17837729
71Abnormal eating behavior (HP:0100738)2.17501881
72Genital tract atresia (HP:0001827)2.16095732
73Menstrual irregularities (HP:0000858)2.15818432
74Large eyes (HP:0001090)2.15580743
7511 pairs of ribs (HP:0000878)2.15565737
76Aplasia/Hypoplasia of the lens (HP:0008063)2.14714953
77Abnormality of the fingertips (HP:0001211)2.13783459
78Colitis (HP:0002583)2.13486077
79Rhinitis (HP:0012384)2.13421325
80Abnormality of the fovea (HP:0000493)2.09265756
81Ankle clonus (HP:0011448)2.09086439
82Joint stiffness (HP:0001387)2.08976029
83Bifid tongue (HP:0010297)2.07104005
84Papillary thyroid carcinoma (HP:0002895)2.06743044
85Poor coordination (HP:0002370)2.06129704
86Peripheral hypomyelination (HP:0007182)2.04757724
87Systemic lupus erythematosus (HP:0002725)2.04306567
88Emphysema (HP:0002097)2.03973741
89Growth hormone excess (HP:0000845)2.03439255
90Rapidly progressive (HP:0003678)2.03409684
91Photophobia (HP:0000613)2.02121553
92Urinary glycosaminoglycan excretion (HP:0003541)2.01524938
93Mucopolysacchariduria (HP:0008155)2.01524938
94Akinesia (HP:0002304)2.00568541
95Spinal canal stenosis (HP:0003416)1.99999476
96Hemiplegia (HP:0002301)1.99633510
97Lissencephaly (HP:0001339)1.98310165
98Cellulitis (HP:0100658)1.98024070
99Hypoplasia of the fovea (HP:0007750)1.97232343
100Aplasia/Hypoplasia of the fovea (HP:0008060)1.97232343
101Optic nerve coloboma (HP:0000588)1.96575792
102Aplasia/Hypoplasia of the brainstem (HP:0007362)1.96193296
103Hypoplasia of the brainstem (HP:0002365)1.96193296
104Polyphagia (HP:0002591)1.92701583
105Diplopia (HP:0000651)1.92000305
106Abnormality of binocular vision (HP:0011514)1.92000305
107Pancreatic cysts (HP:0001737)1.91547138
108Abnormality of polysaccharide metabolism (HP:0011012)1.91369382
109Abnormality of glycosaminoglycan metabolism (HP:0004371)1.91369382
110Abnormality of mucopolysaccharide metabolism (HP:0011020)1.91369382
111Left ventricular hypertrophy (HP:0001712)1.90020987
112Posterior subcapsular cataract (HP:0007787)1.88947014
113Occipital encephalocele (HP:0002085)1.88394579
114Cerebral aneurysm (HP:0004944)1.86908159
115Epileptic encephalopathy (HP:0200134)1.86811607
116Tinnitus (HP:0000360)1.85892475
117Agammaglobulinemia (HP:0004432)1.85734003
118Specific learning disability (HP:0001328)1.85729159
119Abnormal pancreas size (HP:0012094)1.85304674
120Megalencephaly (HP:0001355)1.85083477
121Prolonged QT interval (HP:0001657)1.84332176
122Gastrointestinal stroma tumor (HP:0100723)1.84284263
123Recurrent otitis media (HP:0000403)1.84145323
124Large for gestational age (HP:0001520)1.83867789
125Morphological abnormality of the middle ear (HP:0008609)1.83722737
126Gastrointestinal infarctions (HP:0005244)1.82133933
127Myokymia (HP:0002411)1.81165592
128Bronchomalacia (HP:0002780)1.80525431
129Hemorrhage of the eye (HP:0011885)1.80323659
130Broad face (HP:0000283)1.79312881
131Depression (HP:0000716)1.79301181
132Intestinal atresia (HP:0011100)1.78648143
133Supernumerary nipples (HP:0002558)1.77719385
134Mitral regurgitation (HP:0001653)1.76982199
135Biconcave vertebral bodies (HP:0004586)1.75571399
136Recurrent gram-negative bacterial infections (HP:0005420)1.74981666
137Anxiety (HP:0000739)1.74172516
138Hypokalemia (HP:0002900)1.73006834
139Testicular neoplasm (HP:0010788)1.71725442
140Nephronophthisis (HP:0000090)1.71311623
141Febrile seizures (HP:0002373)1.70424036
142Postaxial hand polydactyly (HP:0001162)1.69385476
143Spastic gait (HP:0002064)1.68481675
144Pointed chin (HP:0000307)1.67958105
145Centrally nucleated skeletal muscle fibers (HP:0003687)1.66901115
146Symptomatic seizures (HP:0011145)1.66616845
147Mediastinal lymphadenopathy (HP:0100721)1.66576461
148Hypercortisolism (HP:0001578)1.66163798
149Increased variability in muscle fiber diameter (HP:0003557)1.65997461
150Foot dorsiflexor weakness (HP:0009027)1.65791807
151Chronic bronchitis (HP:0004469)1.65354282
152Poor suck (HP:0002033)1.65183344
153Scrotal hypoplasia (HP:0000046)1.65134972
154Truncal ataxia (HP:0002078)1.64969183
155Onion bulb formation (HP:0003383)1.64768981
156Germ cell neoplasia (HP:0100728)1.64469175
157Segmental peripheral demyelination/remyelination (HP:0003481)1.63564411
158Abnormality of the foot musculature (HP:0001436)1.63348459
159Abnormal mitochondria in muscle tissue (HP:0008316)1.63308292
160Myotonia (HP:0002486)1.63211807
161Abnormal EKG (HP:0003115)1.63068010
162Protrusio acetabuli (HP:0003179)1.62675788
163Action tremor (HP:0002345)1.62064688
164Muscle fiber splitting (HP:0003555)1.61920730
165Shallow orbits (HP:0000586)1.61356408
166Rimmed vacuoles (HP:0003805)1.60731276
167Thin ribs (HP:0000883)1.59440011
168Male infertility (HP:0003251)1.59432366
169Restrictive lung disease (HP:0002091)1.59204692
170Retinal dysplasia (HP:0007973)1.59145211
171Myositis (HP:0100614)1.58857593
172Progressive inability to walk (HP:0002505)1.58783285
173Bronchiectasis (HP:0002110)1.58646923
174EEG with generalized epileptiform discharges (HP:0011198)1.58621095
175Hyperacusis (HP:0010780)1.57404628
176Anomalous pulmonary venous return (HP:0010772)1.57311897
177Abnormality of hair growth rate (HP:0011363)1.56753403
178Slow-growing hair (HP:0002217)1.56753403
179Neoplasm of the adrenal gland (HP:0100631)1.55276855
180Glomerulonephritis (HP:0000099)1.54923683
181Nuclear cataract (HP:0100018)1.54692817
182Acute necrotizing encephalopathy (HP:0006965)1.54096266
183Anosmia (HP:0000458)1.52759753
184Narrow nasal bridge (HP:0000446)1.52620524
185Adrenal overactivity (HP:0002717)1.51845362
186Cystic liver disease (HP:0006706)1.51647538
187Complement deficiency (HP:0004431)1.51332000
188Infertility (HP:0000789)1.51304493
189Stridor (HP:0010307)1.51153996

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MARK14.23230576
2SIK33.72992577
3MAPK153.15915176
4ERBB32.78319038
5PASK2.36560329
6MAPK132.34492685
7MAP3K122.18552448
8PHKG22.17838258
9PHKG12.17838258
10INSRR2.04180734
11DYRK22.00868718
12SIK21.97676679
13ERN11.96502625
14UHMK11.95590807
15NTRK21.90731418
16MAP2K71.87458811
17PRKD31.85628372
18RIPK41.70510259
19IRAK21.69256956
20EEF2K1.67145236
21HIPK21.65672438
22WNK31.65489735
23CASK1.61579008
24CAMKK11.57254182
25LMTK21.49763154
26DYRK1A1.47731657
27FES1.45789447
28EPHB11.45426358
29DYRK1B1.44576825
30TAOK31.44146565
31MAPK121.43125208
32EPHA31.42591290
33TYRO31.42232804
34SGK4941.38493457
35SGK2231.38493457
36PRPF4B1.37092426
37SGK21.35222458
38TESK11.35056102
39TXK1.34988736
40SIK11.33759315
41BLK1.31866364
42MINK11.31281347
43STK161.28865711
44NTRK11.28010607
45RIPK11.27239442
46DYRK31.26609988
47MYLK1.24759727
48TGFBR11.20844201
49LIMK11.20270942
50CCNB11.18427267
51GRK61.17372621
52TBK11.15768261
53RPS6KA21.14357669
54MAP2K31.13654872
55NTRK31.12468236
56MAP2K41.09688835
57MUSK1.09252624
58MAP3K131.08978232
59BMPR1B1.06194886
60MAP3K71.06094344
61MAP3K111.04049714
62PKN21.01316093
63SMG10.99422775
64PINK10.98846520
65RET0.97515758
66KSR10.97505081
67ARAF0.97209349
68IRAK10.90071419
69MAPK70.89427014
70DAPK20.89190381
71CSK0.89043088
72BRD40.87855179
73PAK60.87130100
74BRAF0.86802087
75BCR0.86041994
76TYK20.85447958
77DAPK10.85043187
78CDK50.84320726
79MAP3K40.83254325
80PDPK10.81629931
81STK240.80794386
82PRKCI0.80400921
83YES10.79012689
84MAP3K60.78704196
85ILK0.78197855
86GRK10.75071967
87MAP2K20.74329578
88KSR20.72969664
89CDC42BPA0.71911298
90CSNK1G30.70930053
91LRRK20.70708404
92PDGFRA0.70450947
93CSNK1A1L0.69766000
94PRKCH0.69735597
95PRKD20.66914005
96SRPK10.66800496
97JAK10.66440894
98TAOK10.65631591
99DDR20.65070188
100PTK60.64897652
101ZAP700.64804926
102FGFR30.64623583
103CDK120.63645165
104HCK0.63507708
105MARK20.63428412
106CDK30.63190771
107FYN0.62412480
108MAP3K100.61752943
109FLT30.61612936
110MAP3K20.60274232
111JAK20.60228198
112PRKD10.59428640
113CDK190.59097576
114CSNK1G20.58447142
115SGK30.58232894
116PDK10.57564599
117MAP3K10.57259227
118PKN10.55464211
119FGFR20.54901256
120BTK0.54420173
121ITK0.54277569
122CDK80.54210044
123TNIK0.53954483
124TNK20.53579601
125MAPK90.53485450
126STK110.52773001
127KIT0.51909924
128RPS6KC10.51324262
129RPS6KL10.51324262
130MAPK40.49168803
131PAK30.46089903
132LCK0.45853247
133TESK20.44306511
134EPHA40.44257548
135MAP3K90.44229526
136MTOR0.43848311
137MAPK110.43201155
138IKBKE0.43185602
139MAP4K10.43006248
140TRIB30.42987588
141ERBB20.42909678
142MAPKAPK30.42822560
143ACVR1B0.42687471
144LYN0.42579063
145RPS6KA60.41384085
146PRKCZ0.41305879
147CAMK40.41076254
148SYK0.40696105
149BMPR20.39273007
150MAP2K60.39118741
151ICK0.36559673
152PIK3CG0.36419829
153CSNK1G10.36388784
154FGFR40.34416618
155PRKCE0.34222574
156ADRBK10.34216505

Predicted pathways (KEGG)

RankGene SetZ-score
1Phototransduction_Homo sapiens_hsa047444.02316177
2Maturity onset diabetes of the young_Homo sapiens_hsa049503.02999606
3Olfactory transduction_Homo sapiens_hsa047402.50956870
4Protein export_Homo sapiens_hsa030602.31728856
5Synaptic vesicle cycle_Homo sapiens_hsa047212.28018279
6Insulin secretion_Homo sapiens_hsa049112.16828159
7Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.14897876
8Circadian entrainment_Homo sapiens_hsa047131.85002401
9GABAergic synapse_Homo sapiens_hsa047271.78624935
10SNARE interactions in vesicular transport_Homo sapiens_hsa041301.72408894
11Taste transduction_Homo sapiens_hsa047421.71542421
12Dopaminergic synapse_Homo sapiens_hsa047281.69413969
13Morphine addiction_Homo sapiens_hsa050321.69335164
14Other glycan degradation_Homo sapiens_hsa005111.67088746
15Cholinergic synapse_Homo sapiens_hsa047251.59420803
16Circadian rhythm_Homo sapiens_hsa047101.53341557
17Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.51220251
18Nicotine addiction_Homo sapiens_hsa050331.49006194
19Vibrio cholerae infection_Homo sapiens_hsa051101.44898740
20Cocaine addiction_Homo sapiens_hsa050301.42411292
21Phospholipase D signaling pathway_Homo sapiens_hsa040721.28438857
22Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.26981924
23Amphetamine addiction_Homo sapiens_hsa050311.25983744
24Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.25522856
25Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.24349676
26N-Glycan biosynthesis_Homo sapiens_hsa005101.24270827
27Osteoclast differentiation_Homo sapiens_hsa043801.23058155
28Serotonergic synapse_Homo sapiens_hsa047261.21737084
29Carbohydrate digestion and absorption_Homo sapiens_hsa049731.20602731
30Aldosterone synthesis and secretion_Homo sapiens_hsa049251.19950125
31Primary immunodeficiency_Homo sapiens_hsa053401.19789448
32Glycosaminoglycan degradation_Homo sapiens_hsa005311.19595789
33Parkinsons disease_Homo sapiens_hsa050121.17876848
34Glutamatergic synapse_Homo sapiens_hsa047241.16678994
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.16666325
36Type II diabetes mellitus_Homo sapiens_hsa049301.11392812
37Colorectal cancer_Homo sapiens_hsa052101.09837547
38Cardiac muscle contraction_Homo sapiens_hsa042601.08410037
39Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.08102968
40Endometrial cancer_Homo sapiens_hsa052131.04459540
41Oxidative phosphorylation_Homo sapiens_hsa001901.03352528
42AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.02481310
43mRNA surveillance pathway_Homo sapiens_hsa030151.02378716
44Leishmaniasis_Homo sapiens_hsa051401.01624720
45Alcoholism_Homo sapiens_hsa050341.01424880
46Staphylococcus aureus infection_Homo sapiens_hsa051501.00542927
47Long-term potentiation_Homo sapiens_hsa047200.97458865
48Notch signaling pathway_Homo sapiens_hsa043300.96952789
49Prion diseases_Homo sapiens_hsa050200.96012516
50Neurotrophin signaling pathway_Homo sapiens_hsa047220.95952527
51T cell receptor signaling pathway_Homo sapiens_hsa046600.93633977
52Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.92855920
53mTOR signaling pathway_Homo sapiens_hsa041500.91947393
54Alzheimers disease_Homo sapiens_hsa050100.91005110
55Axon guidance_Homo sapiens_hsa043600.90956155
56Prolactin signaling pathway_Homo sapiens_hsa049170.90360617
57Regulation of autophagy_Homo sapiens_hsa041400.90199022
58cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89753617
59Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.88743669
60Collecting duct acid secretion_Homo sapiens_hsa049660.88183449
61Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.85166083
62Oxytocin signaling pathway_Homo sapiens_hsa049210.84722697
63Autoimmune thyroid disease_Homo sapiens_hsa053200.84531471
64Allograft rejection_Homo sapiens_hsa053300.83457461
65Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.81731370
66Adipocytokine signaling pathway_Homo sapiens_hsa049200.81607419
67Huntingtons disease_Homo sapiens_hsa050160.81566050
68Basal transcription factors_Homo sapiens_hsa030220.81191066
69cAMP signaling pathway_Homo sapiens_hsa040240.80460608
70Endocytosis_Homo sapiens_hsa041440.80451052
71Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78451736
72Graft-versus-host disease_Homo sapiens_hsa053320.77298752
73Spliceosome_Homo sapiens_hsa030400.76323075
74Toll-like receptor signaling pathway_Homo sapiens_hsa046200.75561033
75Tuberculosis_Homo sapiens_hsa051520.75192937
76Leukocyte transendothelial migration_Homo sapiens_hsa046700.75042957
77Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74458426
78Renal cell carcinoma_Homo sapiens_hsa052110.73924725
79Thyroid hormone signaling pathway_Homo sapiens_hsa049190.72814865
80Hepatitis C_Homo sapiens_hsa051600.72323020
81Renin secretion_Homo sapiens_hsa049240.70848824
82Type I diabetes mellitus_Homo sapiens_hsa049400.70589953
83Pertussis_Homo sapiens_hsa051330.69995259
84Insulin signaling pathway_Homo sapiens_hsa049100.69782827
85Lysosome_Homo sapiens_hsa041420.69273946
86Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.68877259
87Rap1 signaling pathway_Homo sapiens_hsa040150.68668836
88Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.68475679
89Pancreatic cancer_Homo sapiens_hsa052120.68109449
90ErbB signaling pathway_Homo sapiens_hsa040120.67817872
91Inositol phosphate metabolism_Homo sapiens_hsa005620.66552295
92Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.66269836
93Glucagon signaling pathway_Homo sapiens_hsa049220.66262661
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.65867274
95Glycerophospholipid metabolism_Homo sapiens_hsa005640.65730514
96Platelet activation_Homo sapiens_hsa046110.65645304
97Gastric acid secretion_Homo sapiens_hsa049710.65439883
98Viral myocarditis_Homo sapiens_hsa054160.64713857
99Estrogen signaling pathway_Homo sapiens_hsa049150.64593931
100Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.63057621
101Toxoplasmosis_Homo sapiens_hsa051450.62238831
102AMPK signaling pathway_Homo sapiens_hsa041520.62133990
103Phagosome_Homo sapiens_hsa041450.61334753
104Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.61012932
105Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.60656146
106Pancreatic secretion_Homo sapiens_hsa049720.60408393
107Calcium signaling pathway_Homo sapiens_hsa040200.60336058
108Hedgehog signaling pathway_Homo sapiens_hsa043400.59968404
109Gap junction_Homo sapiens_hsa045400.59679643
110GnRH signaling pathway_Homo sapiens_hsa049120.58344284
111Wnt signaling pathway_Homo sapiens_hsa043100.57633341
112Melanogenesis_Homo sapiens_hsa049160.56847098
113Dilated cardiomyopathy_Homo sapiens_hsa054140.56521578
114Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.55692908
115Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.55370593
116Chemokine signaling pathway_Homo sapiens_hsa040620.55301018
117Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.53437248
118Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.53401278
119Oocyte meiosis_Homo sapiens_hsa041140.52493585
120Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.51414860
121Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.51226383
122Acute myeloid leukemia_Homo sapiens_hsa052210.50695858
123Non-small cell lung cancer_Homo sapiens_hsa052230.48475315
124Longevity regulating pathway - mammal_Homo sapiens_hsa042110.48055393
125Salivary secretion_Homo sapiens_hsa049700.48011396
126Basal cell carcinoma_Homo sapiens_hsa052170.47621080
127MAPK signaling pathway_Homo sapiens_hsa040100.46911235
128Vascular smooth muscle contraction_Homo sapiens_hsa042700.45938485
129VEGF signaling pathway_Homo sapiens_hsa043700.45031592
130Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.44475246
131Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.43970205
132Choline metabolism in cancer_Homo sapiens_hsa052310.42222936
133Chronic myeloid leukemia_Homo sapiens_hsa052200.41466498
134B cell receptor signaling pathway_Homo sapiens_hsa046620.40976040
135Long-term depression_Homo sapiens_hsa047300.40640416
136Ras signaling pathway_Homo sapiens_hsa040140.40481551
137Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.38841820
138Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.38103142
139Glioma_Homo sapiens_hsa052140.37612809

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