CKS2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: CKS2 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS2 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects specialized role for the encoded protein. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic metaphase plate congression (GO:0007080)5.87812699
2mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.27945268
3protein localization to kinetochore (GO:0034501)5.10729784
4CENP-A containing nucleosome assembly (GO:0034080)5.06043600
5metaphase plate congression (GO:0051310)5.02787253
6chromatin remodeling at centromere (GO:0031055)4.87645503
7kinetochore organization (GO:0051383)4.79970959
8protein localization to chromosome, centromeric region (GO:0071459)4.75627066
9kinetochore assembly (GO:0051382)4.70862511
10attachment of spindle microtubules to kinetochore (GO:0008608)4.70528012
11regulation of spindle organization (GO:0090224)4.64659423
12establishment of protein localization to mitochondrial membrane (GO:0090151)4.61729295
13DNA replication checkpoint (GO:0000076)4.59461435
14establishment of integrated proviral latency (GO:0075713)4.57329730
15regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.46876276
16DNA replication-independent nucleosome assembly (GO:0006336)4.44847776
17DNA replication-independent nucleosome organization (GO:0034724)4.44847776
18establishment of chromosome localization (GO:0051303)4.42518875
19DNA deamination (GO:0045006)4.40669987
20ATP synthesis coupled proton transport (GO:0015986)4.40442536
21energy coupled proton transport, down electrochemical gradient (GO:0015985)4.40442536
22DNA ligation (GO:0006266)4.35889910
23mitotic sister chromatid segregation (GO:0000070)4.24965577
24maturation of SSU-rRNA (GO:0030490)4.24522851
25histone exchange (GO:0043486)4.22528472
26DNA strand elongation involved in DNA replication (GO:0006271)4.18895331
27telomere maintenance via semi-conservative replication (GO:0032201)4.15978194
28chaperone-mediated protein transport (GO:0072321)4.14509972
29ribosomal small subunit assembly (GO:0000028)4.14421362
30DNA replication initiation (GO:0006270)4.12136487
31regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)4.01184438
32purine nucleobase biosynthetic process (GO:0009113)4.00689188
33DNA strand elongation (GO:0022616)3.99510673
34mitotic nuclear envelope disassembly (GO:0007077)3.94935929
35spindle checkpoint (GO:0031577)3.90938626
36negative regulation of ligase activity (GO:0051352)3.90262395
37negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.90262395
38nucleobase biosynthetic process (GO:0046112)3.89341886
39rRNA modification (GO:0000154)3.88817278
40regulation of mitotic spindle organization (GO:0060236)3.88268866
41mitotic chromosome condensation (GO:0007076)3.87594464
42telomere maintenance via recombination (GO:0000722)3.86395030
43ribosome biogenesis (GO:0042254)3.83990850
44meiotic chromosome segregation (GO:0045132)3.81198524
45ribosomal small subunit biogenesis (GO:0042274)3.79785291
46ribosome assembly (GO:0042255)3.75418968
47ribonucleoprotein complex biogenesis (GO:0022613)3.73459912
48viral transcription (GO:0019083)3.73372779
49positive regulation of chromosome segregation (GO:0051984)3.71172359
50mitotic recombination (GO:0006312)3.69813746
51translational termination (GO:0006415)3.68790138
52sister chromatid segregation (GO:0000819)3.67822911
53nuclear envelope disassembly (GO:0051081)3.63999645
54membrane disassembly (GO:0030397)3.63999645
55anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.63653267
56regulation of chromosome segregation (GO:0051983)3.62702903
57spliceosomal snRNP assembly (GO:0000387)3.57437028
58negative regulation of chromosome segregation (GO:0051985)3.56953330
59negative regulation of mitotic sister chromatid separation (GO:2000816)3.56796751
60negative regulation of mitotic sister chromatid segregation (GO:0033048)3.56796751
61negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.56796751
62negative regulation of sister chromatid segregation (GO:0033046)3.56796751
63mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.56702833
64establishment of viral latency (GO:0019043)3.54502882
65spindle assembly checkpoint (GO:0071173)3.54110912
66ribosomal large subunit biogenesis (GO:0042273)3.53692461
67protein localization to chromosome (GO:0034502)3.52753152
68transcription elongation from RNA polymerase III promoter (GO:0006385)3.52589222
69termination of RNA polymerase III transcription (GO:0006386)3.52589222
70proteasome assembly (GO:0043248)3.52180707
71mitotic spindle checkpoint (GO:0071174)3.51796054
72respiratory electron transport chain (GO:0022904)3.50734075
73negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.47957885
74mitotic spindle assembly checkpoint (GO:0007094)3.47690812
75rRNA processing (GO:0006364)3.47198621
76protein targeting to ER (GO:0045047)3.44221270
77formation of translation preinitiation complex (GO:0001731)3.44212620
78regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.43623819
79DNA topological change (GO:0006265)3.43502977
80negative regulation of mitosis (GO:0045839)3.43428856
81regulation of mitotic metaphase/anaphase transition (GO:0030071)3.43346194
82telomere maintenance via telomere lengthening (GO:0010833)3.42807651
83chromosome segregation (GO:0007059)3.42624585
84electron transport chain (GO:0022900)3.41436814
85exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.40395214
86positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.38035795
87nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.38020099
88translational initiation (GO:0006413)3.37825605
89DNA replication-dependent nucleosome assembly (GO:0006335)3.37301466
90DNA replication-dependent nucleosome organization (GO:0034723)3.37301466
91regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.36821856
92regulation of double-strand break repair via homologous recombination (GO:0010569)3.36412998
93rRNA metabolic process (GO:0016072)3.36261791
94maturation of 5.8S rRNA (GO:0000460)3.35253563
957-methylguanosine mRNA capping (GO:0006370)3.34475896
96regulation of mitochondrial translation (GO:0070129)3.34238316
97translational elongation (GO:0006414)3.32537656
98positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.32268628
99microtubule depolymerization (GO:0007019)3.30188031
100RNA capping (GO:0036260)3.30160090
1017-methylguanosine RNA capping (GO:0009452)3.30160090
102establishment of protein localization to endoplasmic reticulum (GO:0072599)3.30109936
103regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.27810664
104regulation of mitotic spindle checkpoint (GO:1903504)3.27810664
105regulation of exit from mitosis (GO:0007096)3.27235536
106regulation of ubiquitin-protein transferase activity (GO:0051438)3.27006213
107transcription-coupled nucleotide-excision repair (GO:0006283)3.26908855
108regulation of sister chromatid segregation (GO:0033045)3.25028429
109regulation of mitotic sister chromatid separation (GO:0010965)3.25028429
110regulation of mitotic sister chromatid segregation (GO:0033047)3.25028429
111negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.23351065
112positive regulation of ligase activity (GO:0051351)3.23338669
113protein K6-linked ubiquitination (GO:0085020)3.20547182
114spliceosomal complex assembly (GO:0000245)3.20477248
115protein localization to endoplasmic reticulum (GO:0070972)3.20449605
116regulation of ligase activity (GO:0051340)3.15022189
117SRP-dependent cotranslational protein targeting to membrane (GO:0006614)3.14806886
118rRNA methylation (GO:0031167)3.12576875
119nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.12298110
120termination of RNA polymerase I transcription (GO:0006363)3.10636337
121folic acid metabolic process (GO:0046655)3.09250715
122cotranslational protein targeting to membrane (GO:0006613)3.08632167
123G1/S transition of mitotic cell cycle (GO:0000082)3.08293462
124cell cycle G1/S phase transition (GO:0044843)3.08293462
125nucleotide-excision repair, DNA gap filling (GO:0006297)3.08280742
126chromatin assembly or disassembly (GO:0006333)3.08251558
127ventricular cardiac muscle cell development (GO:0055015)3.08140931
128pseudouridine synthesis (GO:0001522)3.07798405
129signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.07468793
130signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.07468793
131signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.07468793
132cellular protein complex disassembly (GO:0043624)3.05823299
133DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.05700310
134deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.05599036

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.57564579
2FOXM1_23109430_ChIP-Seq_U2OS_Human5.44852204
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.21965419
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.97664022
5* FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.86160579
6KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.74859831
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.46215035
8GABP_17652178_ChIP-ChIP_JURKAT_Human3.22658454
9EST1_17652178_ChIP-ChIP_JURKAT_Human3.21732385
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.06175942
11* JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.05953272
12* CREB1_15753290_ChIP-ChIP_HEK293T_Human2.96201033
13* MYC_19079543_ChIP-ChIP_MESCs_Mouse2.92112774
14* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.84308879
15E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.82657731
16* MYC_19030024_ChIP-ChIP_MESCs_Mouse2.75708852
17MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.63500850
18AR_21909140_ChIP-Seq_LNCAP_Human2.52650837
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.50014081
20VDR_23849224_ChIP-Seq_CD4+_Human2.37831215
21* XRN2_22483619_ChIP-Seq_HELA_Human2.36041156
22CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.35585861
23* NELFA_20434984_ChIP-Seq_ESCs_Mouse2.33432488
24NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.12443057
25DCP1A_22483619_ChIP-Seq_HELA_Human2.08973441
26HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.06389232
27SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.05428004
28* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.02986668
29* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.99355973
30FOXP3_21729870_ChIP-Seq_TREG_Human1.98976986
31MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.97098384
32E2F1_21310950_ChIP-Seq_MCF-7_Human1.96641624
33CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.93185394
34GABP_19822575_ChIP-Seq_HepG2_Human1.91886411
35* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.86549433
36TTF2_22483619_ChIP-Seq_HELA_Human1.84323830
37ELF1_17652178_ChIP-ChIP_JURKAT_Human1.80867207
38* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.79907330
39PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.78666616
40* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.75771525
41* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68988609
42THAP11_20581084_ChIP-Seq_MESCs_Mouse1.68759191
43ELK1_19687146_ChIP-ChIP_HELA_Human1.67784003
44POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.61416346
45YY1_21170310_ChIP-Seq_MESCs_Mouse1.57910741
46* HOXB4_20404135_ChIP-ChIP_EML_Mouse1.52583761
47KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.52048672
48SRF_21415370_ChIP-Seq_HL-1_Mouse1.51725832
49YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.44334844
50CIITA_25753668_ChIP-Seq_RAJI_Human1.42647575
51* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.42078900
52* TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.41407378
53* KDM5A_27292631_Chip-Seq_BREAST_Human1.40039108
54POU5F1_16153702_ChIP-ChIP_HESCs_Human1.39459008
55SOX2_16153702_ChIP-ChIP_HESCs_Human1.38910788
56* NANOG_16153702_ChIP-ChIP_HESCs_Human1.32223973
57ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.29826272
58* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.21396836
59PADI4_21655091_ChIP-ChIP_MCF-7_Human1.21345752
60* FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.21203887
61E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.19038551
62TP63_19390658_ChIP-ChIP_HaCaT_Human1.18730175
63* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.18522028
64PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.18416286
65EGR1_19374776_ChIP-ChIP_THP-1_Human1.17073397
66ERG_20887958_ChIP-Seq_HPC-7_Mouse1.17057142
67MYC_18940864_ChIP-ChIP_HL60_Human1.15565220
68EWS_26573619_Chip-Seq_HEK293_Human1.14180085
69DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.12879424
70POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.11856223
71* CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.10155838
72STAT3_1855785_ChIP-Seq_MESCs_Mouse1.08267158
73ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.06182119
74HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.05566431
75ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.03809878
76NOTCH1_21737748_ChIP-Seq_TLL_Human1.03729187
77MYC_22102868_ChIP-Seq_BL_Human1.02087636
78SALL1_21062744_ChIP-ChIP_HESCs_Human1.00415216
79* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.99510041
80POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.98259561
81* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.98096062
82CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.97165292
83ELK1_22589737_ChIP-Seq_MCF10A_Human0.97137694
84SOX2_18555785_ChIP-Seq_MESCs_Mouse0.94648652
85HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94526027
86SOX17_20123909_ChIP-Seq_XEN_Mouse0.92837731
87BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.92513583
88VDR_22108803_ChIP-Seq_LS180_Human0.91437572
89KAP1_22055183_ChIP-Seq_ESCs_Mouse0.91328663
90CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.88979439
91KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.87708250
92FUS_26573619_Chip-Seq_HEK293_Human0.86217263
93* SPI1_23547873_ChIP-Seq_NB4_Human0.85003637
94TFEB_21752829_ChIP-Seq_HELA_Human0.84825221
95SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.84336553
96* SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.83875557
97KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.82999046
98KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.82999046
99KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.82999046
100CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.79755352
101CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.79609937
102* NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.78395402
103CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.78373438
104* GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.77357240
105KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.76970485
106RBPJ_22232070_ChIP-Seq_NCS_Mouse0.75607724
107ESR1_15608294_ChIP-ChIP_MCF-7_Human0.73579953
108* FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.73271677
109* NANOG_21062744_ChIP-ChIP_HESCs_Human0.73059182
110* CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.71097384
111TCF3_18692474_ChIP-Seq_MEFs_Mouse0.70516861
112TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.68792366
113TBX5_21415370_ChIP-Seq_HL-1_Mouse0.68345733
114SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.68239616
115* CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.67357600
116SOX2_18692474_ChIP-Seq_MEFs_Mouse0.66525719
117IRF1_19129219_ChIP-ChIP_H3396_Human0.65347755
118TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.65283720
119HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.64971758
120* PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.62268912
121ZNF274_21170338_ChIP-Seq_K562_Hela0.62014660

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching6.92797581
2MP0003111_abnormal_nucleus_morphology5.25333886
3MP0010094_abnormal_chromosome_stability4.80670538
4MP0004957_abnormal_blastocyst_morpholog4.80563268
5MP0003077_abnormal_cell_cycle4.49504969
6MP0008057_abnormal_DNA_replication3.91322210
7MP0008058_abnormal_DNA_repair3.31130234
8MP0008007_abnormal_cellular_replicative3.19839761
9MP0003718_maternal_effect2.96387693
10MP0008932_abnormal_embryonic_tissue2.77964004
11MP0003123_paternal_imprinting2.38616118
12MP0002396_abnormal_hematopoietic_system2.33006091
13MP0003786_premature_aging2.28127629
14MP0008877_abnormal_DNA_methylation2.20900627
15MP0001730_embryonic_growth_arrest2.20523097
16MP0000350_abnormal_cell_proliferation2.14194192
17MP0000566_synostosis1.81417356
18MP0001529_abnormal_vocalization1.75150601
19MP0002102_abnormal_ear_morphology1.70285547
20MP0010307_abnormal_tumor_latency1.68832343
21MP0000490_abnormal_crypts_of1.67291947
22MP0006292_abnormal_olfactory_placode1.61767567
23MP0008789_abnormal_olfactory_epithelium1.59952087
24MP0001697_abnormal_embryo_size1.59153391
25MP0009333_abnormal_splenocyte_physiolog1.58902991
26MP0005380_embryogenesis_phenotype1.58748755
27MP0001672_abnormal_embryogenesis/_devel1.58748755
28MP0001545_abnormal_hematopoietic_system1.57877242
29MP0005397_hematopoietic_system_phenotyp1.57877242
30MP0002210_abnormal_sex_determination1.56785800
31MP0002080_prenatal_lethality1.47807438
32MP0000313_abnormal_cell_death1.44297153
33MP0002019_abnormal_tumor_incidence1.42949417
34MP0000372_irregular_coat_pigmentation1.40815905
35MP0006072_abnormal_retinal_apoptosis1.38325256
36MP0003315_abnormal_perineum_morphology1.37612738
37MP0003656_abnormal_erythrocyte_physiolo1.35836787
38MP0003984_embryonic_growth_retardation1.34999814
39MP0002085_abnormal_embryonic_tissue1.33794202
40MP0002132_abnormal_respiratory_system1.33338497
41* MP0001929_abnormal_gametogenesis1.31499845
42* MP0001145_abnormal_male_reproductive1.30250546
43MP0002088_abnormal_embryonic_growth/wei1.29975834
44MP0000049_abnormal_middle_ear1.28499342
45MP0003186_abnormal_redox_activity1.27463718
46MP0002697_abnormal_eye_size1.25841372
47* MP0000653_abnormal_sex_gland1.22772191
48MP0004808_abnormal_hematopoietic_stem1.22749526
49MP0003567_abnormal_fetal_cardiomyocyte1.15851172
50MP0002086_abnormal_extraembryonic_tissu1.15675259
51MP0002233_abnormal_nose_morphology1.15051110
52MP0002234_abnormal_pharynx_morphology1.14265910
53MP0009379_abnormal_foot_pigmentation1.12577411
54MP0001119_abnormal_female_reproductive1.12087229
55MP0001485_abnormal_pinna_reflex1.11292996
56MP0005499_abnormal_olfactory_system1.09279806
57MP0005394_taste/olfaction_phenotype1.09279806
58MP0002277_abnormal_respiratory_mucosa1.07947090
59MP0003806_abnormal_nucleotide_metabolis1.07520330
60MP0001346_abnormal_lacrimal_gland1.04305058
61MP0008260_abnormal_autophagy1.04100632
62MP0002084_abnormal_developmental_patter1.02105214
63MP0000631_abnormal_neuroendocrine_gland0.97996235
64MP0005084_abnormal_gallbladder_morpholo0.96322161
65MP0002282_abnormal_trachea_morphology0.95039685
66MP0002398_abnormal_bone_marrow0.94631290
67MP0002722_abnormal_immune_system0.93832586
68MP0003119_abnormal_digestive_system0.91900408
69MP0010352_gastrointestinal_tract_polyps0.91066331
70MP0000689_abnormal_spleen_morphology0.90123844
71MP0000579_abnormal_nail_morphology0.89658215
72MP0004147_increased_porphyrin_level0.88401294
73MP0006036_abnormal_mitochondrial_physio0.87845666
74MP0003755_abnormal_palate_morphology0.87752092
75MP0002160_abnormal_reproductive_system0.87382643
76MP0000703_abnormal_thymus_morphology0.87208234
77MP0005395_other_phenotype0.86283023
78MP0005451_abnormal_body_composition0.85816917
79MP0003763_abnormal_thymus_physiology0.84940886
80MP0002751_abnormal_autonomic_nervous0.84810334
81MP0004133_heterotaxia0.83694329
82MP0001293_anophthalmia0.83084419
83MP0003221_abnormal_cardiomyocyte_apopto0.81978079
84MP0000358_abnormal_cell_content/0.81606061
85MP0006054_spinal_hemorrhage0.79863680
86MP0005408_hypopigmentation0.79646470
87MP0005391_vision/eye_phenotype0.79352421
88MP0004197_abnormal_fetal_growth/weight/0.79278702
89MP0005389_reproductive_system_phenotype0.78979196
90MP0002092_abnormal_eye_morphology0.77500286
91* MP0003699_abnormal_female_reproductive0.77196146
92MP0002736_abnormal_nociception_after0.77077759
93MP0001853_heart_inflammation0.76682475
94MP0000858_altered_metastatic_potential0.75668705
95MP0000537_abnormal_urethra_morphology0.75466758
96MP0002429_abnormal_blood_cell0.75174044
97MP0008995_early_reproductive_senescence0.74731714
98MP0010030_abnormal_orbit_morphology0.74338058
99MP0003121_genomic_imprinting0.72165725
100MP0003941_abnormal_skin_development0.72017316
101MP0005384_cellular_phenotype0.71726566
102MP0000647_abnormal_sebaceous_gland0.71415280
103MP0002653_abnormal_ependyma_morphology0.71389901
104MP0001727_abnormal_embryo_implantation0.71027803
105MP0005621_abnormal_cell_physiology0.70893083
106MP0009672_abnormal_birth_weight0.70681515
107MP0003861_abnormal_nervous_system0.69601601
108MP0001299_abnormal_eye_distance/0.66618264
109MP0009250_abnormal_appendicular_skeleto0.66010027
110MP0003937_abnormal_limbs/digits/tail_de0.65879930
111MP0000762_abnormal_tongue_morphology0.65584836
112MP0005253_abnormal_eye_physiology0.64284724
113* MP0002161_abnormal_fertility/fecundity0.63264472
114MP0009703_decreased_birth_body0.62380714
115* MP0003698_abnormal_male_reproductive0.61884645
116MP0002095_abnormal_skin_pigmentation0.61740774
117MP0009053_abnormal_anal_canal0.61377991
118MP0000716_abnormal_immune_system0.60472434
119MP0005075_abnormal_melanosome_morpholog0.60397198
120MP0005076_abnormal_cell_differentiation0.60063146
121MP0006035_abnormal_mitochondrial_morpho0.59035411
122MP0003646_muscle_fatigue0.58658000
123MP0001764_abnormal_homeostasis0.56327713
124MP0003938_abnormal_ear_development0.54678989
125MP0003890_abnormal_embryonic-extraembry0.53587240
126MP0002111_abnormal_tail_morphology0.52918467
127MP0002938_white_spotting0.52170840
128MP0000750_abnormal_muscle_regeneration0.51311898
129MP0003136_yellow_coat_color0.48043028
130MP0005671_abnormal_response_to0.47382038
131MP0001919_abnormal_reproductive_system0.47347829
132MP0000477_abnormal_intestine_morphology0.45027918
133MP0001286_abnormal_eye_development0.44723243
134MP0009697_abnormal_copulation0.44122581
135MP0002163_abnormal_gland_morphology0.43392257

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)5.86996072
2Abnormality of cells of the erythroid lineage (HP:0012130)5.06059627
3Abnormal number of erythroid precursors (HP:0012131)4.97034506
4Breast hypoplasia (HP:0003187)4.92960682
5Reticulocytopenia (HP:0001896)4.65675012
6Acute necrotizing encephalopathy (HP:0006965)4.53474792
7Carpal bone hypoplasia (HP:0001498)4.14824842
8Acute encephalopathy (HP:0006846)4.12890191
9Oral leukoplakia (HP:0002745)4.12840152
10Abnormal mitochondria in muscle tissue (HP:0008316)4.09720510
11Increased hepatocellular lipid droplets (HP:0006565)4.08092620
12Patellar aplasia (HP:0006443)4.02100432
13Chromsome breakage (HP:0040012)4.00506620
14Chromosomal breakage induced by crosslinking agents (HP:0003221)3.93852160
15Mitochondrial inheritance (HP:0001427)3.88689861
16Aplasia/Hypoplasia of the patella (HP:0006498)3.80114866
17Lipid accumulation in hepatocytes (HP:0006561)3.66159471
18Progressive macrocephaly (HP:0004481)3.60009390
19Impulsivity (HP:0100710)3.58282902
20Aplastic anemia (HP:0001915)3.57279217
21Increased CSF lactate (HP:0002490)3.53872655
22Rough bone trabeculation (HP:0100670)3.49239313
23Abnormality of the preputium (HP:0100587)3.48544113
24Meckel diverticulum (HP:0002245)3.48308828
25Macrocytic anemia (HP:0001972)3.32005851
26Abnormality of the ileum (HP:0001549)3.29090974
27Septo-optic dysplasia (HP:0100842)3.28669963
28Abnormality of chromosome stability (HP:0003220)3.26954788
29Hepatocellular necrosis (HP:0001404)3.20086497
30Pallor (HP:0000980)3.10850849
31Renal Fanconi syndrome (HP:0001994)3.00470164
32Cerebral edema (HP:0002181)3.00193544
33Cerebral hypomyelination (HP:0006808)3.00091640
34Aplasia/Hypoplasia of the uvula (HP:0010293)2.98694183
35Degeneration of anterior horn cells (HP:0002398)2.91726147
36Abnormality of the anterior horn cell (HP:0006802)2.91726147
37Myelodysplasia (HP:0002863)2.90526039
38Small intestinal stenosis (HP:0012848)2.90454365
39Duodenal stenosis (HP:0100867)2.90454365
40Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.89614859
41Absent radius (HP:0003974)2.88092833
42Microretrognathia (HP:0000308)2.85113865
43Hepatic necrosis (HP:0002605)2.77812824
44Bone marrow hypocellularity (HP:0005528)2.76352700
45Abnormal spermatogenesis (HP:0008669)2.73489351
46Secondary amenorrhea (HP:0000869)2.72937204
47Absent thumb (HP:0009777)2.70959670
48Abnormality of the heme biosynthetic pathway (HP:0010472)2.67853608
49Aplasia involving forearm bones (HP:0009822)2.67259029
50Absent forearm bone (HP:0003953)2.67259029
51Absent septum pellucidum (HP:0001331)2.63689117
52Multiple enchondromatosis (HP:0005701)2.61121178
53Horseshoe kidney (HP:0000085)2.57931945
54Facial hemangioma (HP:0000329)2.57834630
55Selective tooth agenesis (HP:0001592)2.54689867
56Colon cancer (HP:0003003)2.54166671
57Nephroblastoma (Wilms tumor) (HP:0002667)2.52096548
58Abnormal trabecular bone morphology (HP:0100671)2.50481497
59Premature graying of hair (HP:0002216)2.48584126
60Premature ovarian failure (HP:0008209)2.44436686
61Hypoplasia of the capital femoral epiphysis (HP:0003090)2.44322958
62Increased intramyocellular lipid droplets (HP:0012240)2.43745780
63Abnormality of the labia minora (HP:0012880)2.41985489
64Microvesicular hepatic steatosis (HP:0001414)2.41700743
65Lactic acidosis (HP:0003128)2.40259926
66Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.39018942
67Sloping forehead (HP:0000340)2.38684584
68Abnormal lung lobation (HP:0002101)2.36917071
69Embryonal renal neoplasm (HP:0011794)2.36318446
70Abnormality of the septum pellucidum (HP:0007375)2.36277912
71Aplasia/Hypoplasia of the sacrum (HP:0008517)2.36016242
72Leukodystrophy (HP:0002415)2.35791008
73Methylmalonic aciduria (HP:0012120)2.33853170
74Cellular immunodeficiency (HP:0005374)2.32713237
75Triphalangeal thumb (HP:0001199)2.32071016
7611 pairs of ribs (HP:0000878)2.32011695
77Respiratory failure (HP:0002878)2.31549279
78Increased serum pyruvate (HP:0003542)2.29869414
79Cleft eyelid (HP:0000625)2.27396342
80Abnormality of the duodenum (HP:0002246)2.27365089
81Respiratory difficulties (HP:0002880)2.26953345
82Supernumerary spleens (HP:0009799)2.24245343
83Exercise intolerance (HP:0003546)2.23228131
84Irregular epiphyses (HP:0010582)2.21817673
85Tracheoesophageal fistula (HP:0002575)2.20833604
86Sparse eyelashes (HP:0000653)2.17833750
87Neoplasm of the pancreas (HP:0002894)2.17640342
88Short thumb (HP:0009778)2.16593501
89Increased nuchal translucency (HP:0010880)2.12138022
90Capillary hemangiomas (HP:0005306)2.09669144
91Pancytopenia (HP:0001876)2.08536031
92Maternal diabetes (HP:0009800)2.08345898
93Abnormality of glycolysis (HP:0004366)2.08082854
94Duplicated collecting system (HP:0000081)2.07874328
95Muscle fiber atrophy (HP:0100295)2.07247336
96Trismus (HP:0000211)2.07139125
97Ureteral duplication (HP:0000073)2.07072000
98Azoospermia (HP:0000027)2.04185928
99Clubbing of toes (HP:0100760)2.02417720
100Type 2 muscle fiber atrophy (HP:0003554)2.01189747
101Squamous cell carcinoma (HP:0002860)1.98251885
102Abnormality of methionine metabolism (HP:0010901)1.96582050
103Optic disc pallor (HP:0000543)1.96267148
104CNS hypomyelination (HP:0003429)1.95603487
105Pendular nystagmus (HP:0012043)1.94964743
106Congenital, generalized hypertrichosis (HP:0004540)1.94755947
107Esophageal atresia (HP:0002032)1.93818062
108Abnormality of reticulocytes (HP:0004312)1.93564220
109Progressive muscle weakness (HP:0003323)1.93467681
110Neoplasm of the colon (HP:0100273)1.91517661
111Atresia of the external auditory canal (HP:0000413)1.91275761
112Hyperglycinemia (HP:0002154)1.91089376
113Volvulus (HP:0002580)1.91040669
114Thrombocytosis (HP:0001894)1.90837351
115Optic nerve hypoplasia (HP:0000609)1.90794597
1163-Methylglutaconic aciduria (HP:0003535)1.90761687
117Medulloblastoma (HP:0002885)1.89863315
118Entropion (HP:0000621)1.88277222
119Pulmonary fibrosis (HP:0002206)1.88183611
120Reduced antithrombin III activity (HP:0001976)1.88009207
121Increased muscle lipid content (HP:0009058)1.87674444
122Aplasia/Hypoplasia of the breasts (HP:0010311)1.87006406
123Abnormal activity of mitochondrial respiratory chain (HP:0011922)1.86902454
124Decreased activity of mitochondrial respiratory chain (HP:0008972)1.86902454
125Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.85823272
126Absent epiphyses (HP:0010577)1.85823272
127Breast aplasia (HP:0100783)1.85752877
128Short middle phalanx of the 5th finger (HP:0004220)1.85599093
129Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.84662686
130Type I transferrin isoform profile (HP:0003642)1.84401216
131Bilateral microphthalmos (HP:0007633)1.83794643
132True hermaphroditism (HP:0010459)1.83009903
133Abnormality of the carotid arteries (HP:0005344)1.82516658
134Pancreatic fibrosis (HP:0100732)1.82396385
135Abnormality of the umbilical cord (HP:0010881)1.81083938
136Sclerocornea (HP:0000647)1.80684149
137Ectopic kidney (HP:0000086)1.80439272
138Slender long bone (HP:0003100)1.78792706
139Prominent nose (HP:0000448)1.78137090
140Increased serum lactate (HP:0002151)1.78056655
141Exertional dyspnea (HP:0002875)1.78007834
142Hypoplasia of the pons (HP:0012110)1.77553339
143Pancreatic cysts (HP:0001737)1.77010361
144Abnormality of renal resorption (HP:0011038)1.76868722
145Holoprosencephaly (HP:0001360)1.76607646
146Abnormality of the renal collecting system (HP:0004742)1.76425489
147Hemivertebrae (HP:0002937)1.75887753
148Hypoplasia of the radius (HP:0002984)1.75511137
149Anophthalmia (HP:0000528)1.74787494
150Abnormality of the pons (HP:0007361)1.74678151
151Cafe-au-lait spot (HP:0000957)1.74268303
152Abnormal number of incisors (HP:0011064)1.74081562
153Megaloblastic anemia (HP:0001889)1.74034959
154Methylmalonic acidemia (HP:0002912)1.73753981

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB15.99507775
2WEE15.37573357
3VRK24.37951005
4EIF2AK13.30385866
5CDC73.21201018
6NEK23.21196792
7BRSK23.00211298
8PLK42.92699755
9SRPK12.66684265
10NME22.62713455
11STK162.58895428
12TTK2.58667702
13PLK12.35044109
14ACVR1B2.33736511
15VRK12.32536270
16NEK12.18091972
17BRSK12.02215722
18EIF2AK31.98366979
19TAF11.95497564
20AURKB1.88357552
21DYRK31.85928733
22PLK31.81000562
23MKNK21.70544242
24TSSK61.69564008
25MKNK11.68193564
26CCNB11.65222891
27CDK71.49751934
28CHEK21.45211973
29RPS6KA41.41354206
30TESK21.39895277
31AURKA1.39654152
32MAP3K81.24646622
33ATR1.23982169
34TNIK1.23205552
35TLK11.22009119
36EIF2AK21.13980646
37BRAF1.13103581
38STK41.06485434
39RPS6KB21.06463422
40CDK41.05687527
41CHEK11.02518740
42ZAK1.02470947
43TRIM280.99621369
44PIM20.95426646
45STK100.92532162
46LATS20.91325628
47WNK30.88531202
48CDK80.87901484
49EPHA20.84334742
50PBK0.80100575
51STK38L0.78990924
52STK30.77931423
53MELK0.75942658
54PIM10.71312394
55PDK20.67032217
56ATM0.66123636
57CDK20.64298291
58PAK10.63712709
59CSNK2A10.63196499
60RAF10.63031362
61KDR0.61148236
62EEF2K0.61088683
63PAK40.60779577
64ABL20.59414267
65IRAK30.55833401
66CDK10.54987606
67BMPR1B0.54779790
68CSNK2A20.53923716
69CSNK1G10.53458335
70CDK190.53104172
71BCKDK0.52792494
72SCYL20.51934603
73PRKCI0.51486296
74MAPKAPK30.50854306
75DYRK20.50295987
76NME10.50212750
77UHMK10.47692344
78MAP3K100.46058525
79MAP3K60.44650827
80PNCK0.43640810
81CDK60.42461474
82MAP3K110.39577756
83MARK30.39537096
84PASK0.38522202
85PLK20.37364024
86CSNK1G20.36663820
87MAP3K120.36227943
88RPS6KA50.35415372
89TEC0.34053307
90LRRK20.33885863
91ERBB40.33863368
92MUSK0.33125836
93CSNK1A1L0.32535536
94ARAF0.32125905
95BCR0.31978034
96MAPKAPK50.31956917
97STK240.29277748
98TGFBR10.28178538
99CDK30.27432797
100NUAK10.27400635
101FGFR10.26362283
102INSRR0.26318487
103LATS10.25568169
104TAOK10.25468756
105ERBB30.24454505
106MAP4K20.22871918
107CDK120.22627209
108CLK10.21576950
109NEK90.20786610
110CSNK1G30.20177059
111PRKCG0.20171183
112MAP4K10.20125182
113CDK11A0.19511545
114MAP2K30.19151629
115CDK180.19085939
116CDK150.17902288
117TYK20.17612667
118MST40.16657470
119MAP3K40.16602295
120ALK0.16110889
121CDK140.15660219
122ILK0.15603298
123AKT30.15495139
124IRAK40.15228742
125DAPK30.15136090
126PRKDC0.14977301
127AKT20.14776863
128OXSR10.14769963
129MAP3K50.14750830
130BRD40.13824349
131IKBKB0.12997554
132CSNK1E0.12479793

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030304.58978658
2RNA polymerase_Homo sapiens_hsa030204.23313723
3Ribosome_Homo sapiens_hsa030103.86766625
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.82140458
5Mismatch repair_Homo sapiens_hsa034303.78873241
6Proteasome_Homo sapiens_hsa030503.39528068
7Spliceosome_Homo sapiens_hsa030403.24480606
8Homologous recombination_Homo sapiens_hsa034403.20970415
9Cell cycle_Homo sapiens_hsa041103.11256925
10RNA transport_Homo sapiens_hsa030133.08595907
11Pyrimidine metabolism_Homo sapiens_hsa002402.85050977
12Nucleotide excision repair_Homo sapiens_hsa034202.80535933
13Base excision repair_Homo sapiens_hsa034102.78424998
14Fanconi anemia pathway_Homo sapiens_hsa034602.41740791
15Basal transcription factors_Homo sapiens_hsa030222.37868516
16Vitamin B6 metabolism_Homo sapiens_hsa007502.33188746
17RNA degradation_Homo sapiens_hsa030182.07445581
18One carbon pool by folate_Homo sapiens_hsa006702.01156405
19p53 signaling pathway_Homo sapiens_hsa041151.93052685
20Non-homologous end-joining_Homo sapiens_hsa034501.62496898
21Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.62257980
22Purine metabolism_Homo sapiens_hsa002301.61111570
23Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.54884970
24Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.42083976
25mRNA surveillance pathway_Homo sapiens_hsa030151.41336264
26Propanoate metabolism_Homo sapiens_hsa006401.37608841
27Oocyte meiosis_Homo sapiens_hsa041141.27469568
28Folate biosynthesis_Homo sapiens_hsa007901.24145555
29Pyruvate metabolism_Homo sapiens_hsa006201.23652334
30Pentose phosphate pathway_Homo sapiens_hsa000301.21560457
31Epstein-Barr virus infection_Homo sapiens_hsa051691.21137329
32Cardiac muscle contraction_Homo sapiens_hsa042601.18304226
33Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.13895648
34Cysteine and methionine metabolism_Homo sapiens_hsa002701.03582399
35Protein export_Homo sapiens_hsa030600.97645538
36Systemic lupus erythematosus_Homo sapiens_hsa053220.95358467
37Steroid biosynthesis_Homo sapiens_hsa001000.94867984
38Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.87784469
39Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.87538307
40Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.87323344
41Herpes simplex infection_Homo sapiens_hsa051680.86517167
42Fatty acid elongation_Homo sapiens_hsa000620.84748770
43Huntingtons disease_Homo sapiens_hsa050160.83677504
44Sulfur relay system_Homo sapiens_hsa041220.82732308
45Drug metabolism - other enzymes_Homo sapiens_hsa009830.82607718
46Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.74677051
47Biosynthesis of amino acids_Homo sapiens_hsa012300.74194855
48Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71774045
49Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.69075429
50Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.68978187
51Viral carcinogenesis_Homo sapiens_hsa052030.68169233
52Selenocompound metabolism_Homo sapiens_hsa004500.66654836
53Antigen processing and presentation_Homo sapiens_hsa046120.66031687
54Basal cell carcinoma_Homo sapiens_hsa052170.65163856
55Glutathione metabolism_Homo sapiens_hsa004800.62371657
56Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62143920
57Regulation of autophagy_Homo sapiens_hsa041400.58770378
58Cyanoamino acid metabolism_Homo sapiens_hsa004600.55922544
59Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.54941693
60Parkinsons disease_Homo sapiens_hsa050120.54624802
61HTLV-I infection_Homo sapiens_hsa051660.53228683
62Thyroid cancer_Homo sapiens_hsa052160.43212386
63Pentose and glucuronate interconversions_Homo sapiens_hsa000400.41491632
64Oxidative phosphorylation_Homo sapiens_hsa001900.40128141
65Hedgehog signaling pathway_Homo sapiens_hsa043400.39140165
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.37700713
67Metabolic pathways_Homo sapiens_hsa011000.37695301
68Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.37446005
69MicroRNAs in cancer_Homo sapiens_hsa052060.36264513
70Sulfur metabolism_Homo sapiens_hsa009200.35583975
71Peroxisome_Homo sapiens_hsa041460.34395247
72Carbon metabolism_Homo sapiens_hsa012000.32311754
73Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.31806983
74Arachidonic acid metabolism_Homo sapiens_hsa005900.31272034
75TGF-beta signaling pathway_Homo sapiens_hsa043500.30856020
76* Small cell lung cancer_Homo sapiens_hsa052220.29262335
77Primary immunodeficiency_Homo sapiens_hsa053400.28934260
78Apoptosis_Homo sapiens_hsa042100.28688514
79Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.27731580
80Wnt signaling pathway_Homo sapiens_hsa043100.27566790
81Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.27545710
82Intestinal immune network for IgA production_Homo sapiens_hsa046720.26590131
83Phototransduction_Homo sapiens_hsa047440.26035372
84N-Glycan biosynthesis_Homo sapiens_hsa005100.25420120
85Hepatitis B_Homo sapiens_hsa051610.25205422
86Legionellosis_Homo sapiens_hsa051340.24555983
87Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.23901078
88Butanoate metabolism_Homo sapiens_hsa006500.23383878
89Vitamin digestion and absorption_Homo sapiens_hsa049770.23231511
90Linoleic acid metabolism_Homo sapiens_hsa005910.23041290
91Nitrogen metabolism_Homo sapiens_hsa009100.22825364
92Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.22468240
93Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.21827125
94beta-Alanine metabolism_Homo sapiens_hsa004100.21000665
95Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.20929810
96Transcriptional misregulation in cancer_Homo sapiens_hsa052020.19945361
97Measles_Homo sapiens_hsa051620.19116285
98Hematopoietic cell lineage_Homo sapiens_hsa046400.18754783
99NF-kappa B signaling pathway_Homo sapiens_hsa040640.17876484
100Tyrosine metabolism_Homo sapiens_hsa003500.17647923
101Fatty acid metabolism_Homo sapiens_hsa012120.17615160
102Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.17337774
103Tryptophan metabolism_Homo sapiens_hsa003800.17236977
104Fatty acid degradation_Homo sapiens_hsa000710.17148350
105Fructose and mannose metabolism_Homo sapiens_hsa000510.16848472
106Renin-angiotensin system_Homo sapiens_hsa046140.16670249
107Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.16651351
108Influenza A_Homo sapiens_hsa051640.15720382
109Asthma_Homo sapiens_hsa053100.15324508
110Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.15246361
111Chemical carcinogenesis_Homo sapiens_hsa052040.14881755
112Arginine and proline metabolism_Homo sapiens_hsa003300.14570714
113NOD-like receptor signaling pathway_Homo sapiens_hsa046210.13983436
114Glycerophospholipid metabolism_Homo sapiens_hsa005640.13421213
115Retinol metabolism_Homo sapiens_hsa008300.13233427
116Alcoholism_Homo sapiens_hsa050340.12836601
117Colorectal cancer_Homo sapiens_hsa052100.12257684
118Maturity onset diabetes of the young_Homo sapiens_hsa049500.11727152
119Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.11260446
120Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.11162840
121FoxO signaling pathway_Homo sapiens_hsa040680.09955751
122RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.09105515
123Galactose metabolism_Homo sapiens_hsa000520.08920445
124Shigellosis_Homo sapiens_hsa051310.08254391
1252-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.07482214
126alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.07208744
127Circadian rhythm_Homo sapiens_hsa047100.06971882
128HIF-1 signaling pathway_Homo sapiens_hsa040660.04338143
129Hippo signaling pathway_Homo sapiens_hsa043900.04305203
130Fat digestion and absorption_Homo sapiens_hsa049750.03355365
131Bladder cancer_Homo sapiens_hsa052190.02328714
132Caffeine metabolism_Homo sapiens_hsa002320.01114115
133Alzheimers disease_Homo sapiens_hsa050100.00967534

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »