Rank | Gene Set | Z-score |
---|---|---|
1 | axonemal dynein complex assembly (GO:0070286) | 9.29299003 |
2 | cilium or flagellum-dependent cell motility (GO:0001539) | 7.78771621 |
3 | branching involved in prostate gland morphogenesis (GO:0060442) | 6.81161068 |
4 | oligosaccharide biosynthetic process (GO:0009312) | 6.46210724 |
5 | cilium movement (GO:0003341) | 6.36095048 |
6 | COPI coating of Golgi vesicle (GO:0048205) | 6.04938600 |
7 | Golgi transport vesicle coating (GO:0048200) | 6.04938600 |
8 | motile cilium assembly (GO:0044458) | 5.89400197 |
9 | valine metabolic process (GO:0006573) | 5.88196854 |
10 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 5.69943997 |
11 | sulfate transmembrane transport (GO:1902358) | 5.68000298 |
12 | L-fucose catabolic process (GO:0042355) | 5.35484240 |
13 | fucose catabolic process (GO:0019317) | 5.35484240 |
14 | L-fucose metabolic process (GO:0042354) | 5.35484240 |
15 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 5.34754830 |
16 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 5.30659508 |
17 | intestinal epithelial cell development (GO:0060576) | 5.16522775 |
18 | epithelial cilium movement (GO:0003351) | 5.10043775 |
19 | sperm capacitation (GO:0048240) | 5.06893543 |
20 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 4.87405929 |
21 | primary alcohol catabolic process (GO:0034310) | 4.74554753 |
22 | protein retention in ER lumen (GO:0006621) | 4.67670417 |
23 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 4.60052861 |
24 | sulfate transport (GO:0008272) | 4.56689046 |
25 | prostate gland epithelium morphogenesis (GO:0060740) | 4.54392388 |
26 | fucose metabolic process (GO:0006004) | 4.53192757 |
27 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 4.53150551 |
28 | renal absorption (GO:0070293) | 4.52800584 |
29 | epithelial cell differentiation involved in prostate gland development (GO:0060742) | 4.50980133 |
30 | artery development (GO:0060840) | 4.50624852 |
31 | sulfur amino acid catabolic process (GO:0000098) | 4.44533830 |
32 | bicarbonate transport (GO:0015701) | 4.43742697 |
33 | regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768) | 4.43477853 |
34 | ER-associated ubiquitin-dependent protein catabolic process (GO:0030433) | 4.34890812 |
35 | water homeostasis (GO:0030104) | 4.23930396 |
36 | ethanol oxidation (GO:0006069) | 4.22845955 |
37 | axoneme assembly (GO:0035082) | 4.19538384 |
38 | N-glycan processing (GO:0006491) | 4.18311437 |
39 | gap junction assembly (GO:0016264) | 4.17225822 |
40 | activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171) | 4.13255569 |
41 | mannose metabolic process (GO:0006013) | 4.11324646 |
42 | establishment of skin barrier (GO:0061436) | 4.10629011 |
43 | branched-chain amino acid metabolic process (GO:0009081) | 4.10626698 |
44 | transcytosis (GO:0045056) | 4.10226230 |
45 | regulation of water loss via skin (GO:0033561) | 4.10219128 |
46 | activation of signaling protein activity involved in unfolded protein response (GO:0006987) | 4.02440133 |
47 | positive regulation of p38MAPK cascade (GO:1900745) | 3.98600670 |
48 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.93339026 |
49 | epithelial cell maturation (GO:0002070) | 3.91579774 |
50 | galactose catabolic process (GO:0019388) | 3.90010732 |
51 | beta-amyloid metabolic process (GO:0050435) | 3.87637651 |
52 | positive regulation of nuclease activity (GO:0032075) | 3.80389375 |
53 | * calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules (GO:0016338) | 3.74345738 |
54 | polyol transport (GO:0015791) | 3.71333535 |
55 | vitamin transmembrane transport (GO:0035461) | 3.71141020 |
56 | hormone catabolic process (GO:0042447) | 3.70884742 |
57 | cysteine metabolic process (GO:0006534) | 3.62926057 |
58 | peptide catabolic process (GO:0043171) | 3.57954184 |
59 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 3.57247649 |
60 | sodium ion homeostasis (GO:0055078) | 3.56163197 |
61 | branched-chain amino acid catabolic process (GO:0009083) | 3.55540142 |
62 | positive regulation of steroid hormone secretion (GO:2000833) | 3.55334027 |
63 | opsonization (GO:0008228) | 3.53356592 |
64 | diterpenoid biosynthetic process (GO:0016102) | 3.52801628 |
65 | cellular modified amino acid catabolic process (GO:0042219) | 3.51769167 |
66 | hypotonic response (GO:0006971) | 3.51050312 |
67 | regulation of transforming growth factor beta1 production (GO:0032908) | 3.49920300 |
68 | hemidesmosome assembly (GO:0031581) | 3.47884621 |
69 | left/right pattern formation (GO:0060972) | 3.47544209 |
70 | regulation of receptor binding (GO:1900120) | 3.44201528 |
71 | drug transmembrane transport (GO:0006855) | 3.44126382 |
72 | flavonoid metabolic process (GO:0009812) | 3.43407759 |
73 | regulation of nuclease activity (GO:0032069) | 3.40458201 |
74 | endoplasmic reticulum unfolded protein response (GO:0030968) | 3.37292940 |
75 | transepithelial transport (GO:0070633) | 3.32547894 |
76 | iron ion import (GO:0097286) | 3.28958710 |
77 | positive regulation of catenin import into nucleus (GO:0035413) | 3.26871262 |
78 | response to testosterone (GO:0033574) | 3.26490977 |
79 | regulation of apoptotic process involved in morphogenesis (GO:1902337) | 3.26083021 |
80 | glutathione biosynthetic process (GO:0006750) | 3.25278357 |
81 | cellular response to unfolded protein (GO:0034620) | 3.25082469 |
82 | response to mercury ion (GO:0046689) | 3.24929613 |
83 | carnitine metabolic process (GO:0009437) | 3.24798008 |
84 | positive regulation of growth hormone secretion (GO:0060124) | 3.23565023 |
85 | excretion (GO:0007588) | 3.22733753 |
86 | exocrine pancreas development (GO:0031017) | 3.22729682 |
87 | mitotic cell cycle arrest (GO:0071850) | 3.22218395 |
88 | renal system process involved in regulation of blood volume (GO:0001977) | 3.21884684 |
89 | desmosome organization (GO:0002934) | 3.21580120 |
90 | intestinal absorption (GO:0050892) | 3.20775780 |
91 | keratinocyte development (GO:0003334) | 3.19516906 |
92 | lung secretory cell differentiation (GO:0061140) | 3.19311172 |
93 | biotin metabolic process (GO:0006768) | 3.18280327 |
94 | carnitine transmembrane transport (GO:1902603) | 3.17470785 |
95 | sulfur compound transport (GO:0072348) | 3.16626027 |
96 | ER-nucleus signaling pathway (GO:0006984) | 3.16212183 |
97 | 2-oxoglutarate metabolic process (GO:0006103) | 3.15631376 |
98 | potassium ion homeostasis (GO:0055075) | 3.15331340 |
99 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.13007608 |
100 | response to endoplasmic reticulum stress (GO:0034976) | 3.12936340 |
101 | apical protein localization (GO:0045176) | 3.12854505 |
102 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 3.12496254 |
103 | nonribosomal peptide biosynthetic process (GO:0019184) | 3.11828155 |
104 | short-chain fatty acid metabolic process (GO:0046459) | 3.11303747 |
105 | purine nucleotide transport (GO:0015865) | 3.08733978 |
106 | regulation of p38MAPK cascade (GO:1900744) | 3.08187359 |
107 | galactose metabolic process (GO:0006012) | 3.07429152 |
108 | purine ribonucleotide transport (GO:0015868) | 3.04432755 |
109 | COPII vesicle coating (GO:0048208) | 3.03868152 |
110 | carnitine transport (GO:0015879) | 3.03848640 |
111 | amino-acid betaine transport (GO:0015838) | 3.03848640 |
112 | zinc ion transport (GO:0006829) | 3.01936055 |
113 | purine nucleoside bisphosphate biosynthetic process (GO:0034033) | 3.01657430 |
114 | ribonucleoside bisphosphate biosynthetic process (GO:0034030) | 3.01657430 |
115 | nucleoside bisphosphate biosynthetic process (GO:0033866) | 3.01657430 |
116 | cellular response to topologically incorrect protein (GO:0035967) | 3.00582399 |
117 | thyroid hormone generation (GO:0006590) | 2.97651725 |
118 | cellular glucuronidation (GO:0052695) | 2.96925240 |
119 | positive regulation of natural killer cell differentiation (GO:0032825) | 2.95571566 |
120 | primary alcohol metabolic process (GO:0034308) | 2.94992442 |
121 | hexose catabolic process (GO:0019320) | 2.94588400 |
122 | regulation of cilium movement (GO:0003352) | 2.93953571 |
123 | apoptotic cell clearance (GO:0043277) | 2.91406328 |
124 | one-carbon compound transport (GO:0019755) | 2.89902806 |
125 | regulation of protein glycosylation (GO:0060049) | 2.89043553 |
126 | lysine catabolic process (GO:0006554) | 2.88928021 |
127 | lysine metabolic process (GO:0006553) | 2.88928021 |
128 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.88916812 |
129 | regulation of intracellular pH (GO:0051453) | 2.88613330 |
130 | pharyngeal system development (GO:0060037) | 2.88270661 |
131 | ventricular cardiac muscle cell action potential (GO:0086005) | 2.88232977 |
132 | protein N-linked glycosylation via asparagine (GO:0018279) | 2.87804622 |
133 | urate metabolic process (GO:0046415) | 2.87150528 |
134 | uronic acid metabolic process (GO:0006063) | 2.87057681 |
135 | glucuronate metabolic process (GO:0019585) | 2.87057681 |
136 | peptidyl-asparagine modification (GO:0018196) | 2.85732744 |
137 | regulation of interleukin-5 production (GO:0032674) | 2.85504839 |
138 | mammary gland alveolus development (GO:0060749) | 2.84308473 |
139 | regulation of interleukin-13 production (GO:0032656) | 2.84242686 |
140 | positive regulation of synaptic transmission, GABAergic (GO:0032230) | 2.84204839 |
141 | ethanol metabolic process (GO:0006067) | 2.81742658 |
142 | actin filament depolymerization (GO:0030042) | 2.80012369 |
143 | keratinocyte proliferation (GO:0043616) | 2.78324215 |
144 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.76996604 |
145 | multicellular organismal water homeostasis (GO:0050891) | 2.76929260 |
146 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.76886317 |
147 | retinoic acid metabolic process (GO:0042573) | 2.76560923 |
148 | drug transport (GO:0015893) | 2.76304584 |
149 | negative regulation of cell fate commitment (GO:0010454) | 2.75244546 |
150 | O-glycan processing (GO:0016266) | 2.74295227 |
151 | mammary gland epithelial cell differentiation (GO:0060644) | 2.73925001 |
152 | one-carbon metabolic process (GO:0006730) | 2.73724037 |
153 | quaternary ammonium group transport (GO:0015697) | 2.71235809 |
154 | amino-acid betaine metabolic process (GO:0006577) | 2.70594471 |
155 | phosphate ion transport (GO:0006817) | 2.70522495 |
156 | regulation of tight junction assembly (GO:2000810) | 2.70150724 |
157 | glomerular epithelial cell development (GO:0072310) | 2.69975060 |
158 | left/right axis specification (GO:0070986) | 2.69834335 |
159 | protein N-linked glycosylation (GO:0006487) | 2.69756073 |
160 | sequestering of metal ion (GO:0051238) | 2.68920886 |
161 | ectoderm development (GO:0007398) | 2.68536894 |
162 | thyroid hormone metabolic process (GO:0042403) | 2.68093351 |
163 | monosaccharide catabolic process (GO:0046365) | 2.67781052 |
164 | angiotensin maturation (GO:0002003) | 2.65854438 |
165 | oxaloacetate metabolic process (GO:0006107) | 2.63864603 |
166 | vesicle coating (GO:0006901) | 2.63807308 |
167 | sphingomyelin metabolic process (GO:0006684) | 2.63729484 |
168 | fucosylation (GO:0036065) | 2.63691979 |
169 | proline metabolic process (GO:0006560) | 2.63602331 |
170 | glandular epithelial cell differentiation (GO:0002067) | 2.62629407 |
171 | monovalent inorganic cation homeostasis (GO:0055067) | 2.59870735 |
172 | antibacterial humoral response (GO:0019731) | 2.58371225 |
173 | tricarboxylic acid metabolic process (GO:0072350) | 2.58368309 |
174 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic proc | 2.57912415 |
175 | regulation of pH (GO:0006885) | 2.56417208 |
176 | regulation of cellular pH (GO:0030641) | 2.54663532 |
177 | regulation of protein localization to cell surface (GO:2000008) | 2.53971779 |
178 | asymmetric protein localization (GO:0008105) | 2.53073668 |
179 | neurotransmitter biosynthetic process (GO:0042136) | 2.50613064 |
180 | auditory receptor cell differentiation (GO:0042491) | 2.47967187 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.44046831 |
2 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 4.32470977 |
3 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 4.08782364 |
4 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 3.86990207 |
5 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 3.32929179 |
6 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 3.11872146 |
7 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 2.84388987 |
8 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.73082943 |
9 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.56335149 |
10 | SOX2_20726797_ChIP-Seq_SW620_Human | 2.55313143 |
11 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 2.44037811 |
12 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.38474618 |
13 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.36891995 |
14 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 2.36497352 |
15 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 2.29170168 |
16 | GATA4_25053715_ChIP-Seq_YYC3_Human | 2.28951848 |
17 | * AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 2.19087826 |
18 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.16049629 |
19 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 2.11279181 |
20 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 2.03673069 |
21 | GATA6_25053715_ChIP-Seq_YYC3_Human | 2.00459970 |
22 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 1.98049483 |
23 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.97308741 |
24 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.95831550 |
25 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.94228137 |
26 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.93552415 |
27 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 1.92202427 |
28 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.92097700 |
29 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.88752493 |
30 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.88686130 |
31 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 1.85004066 |
32 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.74624126 |
33 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 1.72813496 |
34 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.70816429 |
35 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.68633602 |
36 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.66568247 |
37 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.65594613 |
38 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.62840565 |
39 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.61100318 |
40 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.61100318 |
41 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.59796729 |
42 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.59590564 |
43 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.58900255 |
44 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.55322571 |
45 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.54909242 |
46 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.54410812 |
47 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.54137719 |
48 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.52319514 |
49 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.51249801 |
50 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.50915748 |
51 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.50259759 |
52 | GATA1_22025678_ChIP-Seq_K562_Human | 1.49765780 |
53 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.48385473 |
54 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.48385473 |
55 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.48385473 |
56 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.45466809 |
57 | * FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.45133754 |
58 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.41158004 |
59 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.40850814 |
60 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.39167560 |
61 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.37410887 |
62 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.35520857 |
63 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.35520857 |
64 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.33451813 |
65 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.32249832 |
66 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.30959927 |
67 | RXR_22108803_ChIP-Seq_LS180_Human | 1.27870384 |
68 | KLF5_25053715_ChIP-Seq_YYC3_Human | 1.20772722 |
69 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.18590869 |
70 | CJUN_26792858_Chip-Seq_BT549_Human | 1.16772818 |
71 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.16120128 |
72 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.14530748 |
73 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.14250188 |
74 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.14199922 |
75 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.13650987 |
76 | * PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.13090651 |
77 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.10648015 |
78 | * NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.10272520 |
79 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 1.09738992 |
80 | ATF3_27146783_Chip-Seq_COLON_Human | 1.09703297 |
81 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.08338171 |
82 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.07008444 |
83 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.06294845 |
84 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.05788268 |
85 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.05475231 |
86 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.05475231 |
87 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.05029620 |
88 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.04824642 |
89 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.04805352 |
90 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.04091925 |
91 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.03519031 |
92 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.02584121 |
93 | TP63_22573176_ChIP-Seq_HFKS_Human | 1.02156530 |
94 | * FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.02023691 |
95 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.01936371 |
96 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.97798575 |
97 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.97283398 |
98 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.96133510 |
99 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.95740288 |
100 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.92168120 |
101 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 0.91729826 |
102 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.90809177 |
103 | ELF5_23300383_ChIP-Seq_T47D_Human | 0.89565175 |
104 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.89458393 |
105 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 0.87268501 |
106 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 0.87037709 |
107 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.85732830 |
108 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.84195954 |
109 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.84118344 |
110 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 0.83579603 |
111 | * BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.82722911 |
112 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.80600616 |
113 | SMC4_20622854_ChIP-Seq_HELA_Human | 0.80521238 |
114 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 0.78124647 |
115 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.76381712 |
116 | GATA1_19941826_ChIP-Seq_K562_Human | 0.74309038 |
117 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.73308222 |
118 | GATA2_19941826_ChIP-Seq_K562_Human | 0.72205656 |
119 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.65756879 |
120 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.65578883 |
121 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.65494471 |
122 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 0.65483228 |
123 | CEBPB_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 0.64114274 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0010234_abnormal_vibrissa_follicle | 5.62216113 |
2 | MP0004043_abnormal_pH_regulation | 4.59325349 |
3 | MP0003300_gastrointestinal_ulcer | 4.19960032 |
4 | MP0009379_abnormal_foot_pigmentation | 3.20881396 |
5 | MP0004264_abnormal_extraembryonic_tissu | 3.17135031 |
6 | MP0005310_abnormal_salivary_gland | 3.06716944 |
7 | MP0000537_abnormal_urethra_morphology | 3.01762902 |
8 | MP0010386_abnormal_urinary_bladder | 3.00930712 |
9 | MP0001756_abnormal_urination | 2.84603579 |
10 | MP0001765_abnormal_ion_homeostasis | 2.77251747 |
11 | MP0002166_altered_tumor_susceptibility | 2.77039909 |
12 | MP0002277_abnormal_respiratory_mucosa | 2.51290200 |
13 | MP0001873_stomach_inflammation | 2.42088937 |
14 | MP0001881_abnormal_mammary_gland | 2.41825829 |
15 | MP0002009_preneoplasia | 2.29485141 |
16 | MP0009643_abnormal_urine_homeostasis | 2.22168059 |
17 | MP0001666_abnormal_nutrient_absorption | 2.18163685 |
18 | MP0000613_abnormal_salivary_gland | 2.14917501 |
19 | MP0002006_tumorigenesis | 2.04880821 |
20 | MP0005647_abnormal_sex_gland | 2.04369764 |
21 | MP0005636_abnormal_mineral_homeostasis | 2.02344986 |
22 | MP0002796_impaired_skin_barrier | 2.00533726 |
23 | MP0002098_abnormal_vibrissa_morphology | 1.97477600 |
24 | MP0000538_abnormal_urinary_bladder | 1.94862134 |
25 | MP0002139_abnormal_hepatobiliary_system | 1.92509833 |
26 | MP0005220_abnormal_exocrine_pancreas | 1.92403649 |
27 | MP0003705_abnormal_hypodermis_morpholog | 1.88879469 |
28 | MP0010678_abnormal_skin_adnexa | 1.84484937 |
29 | MP0005332_abnormal_amino_acid | 1.79232118 |
30 | MP0004019_abnormal_vitamin_homeostasis | 1.73996485 |
31 | MP0008961_abnormal_basal_metabolism | 1.72402218 |
32 | MP0002136_abnormal_kidney_physiology | 1.67526602 |
33 | MP0009780_abnormal_chondrocyte_physiolo | 1.66654191 |
34 | MP0001346_abnormal_lacrimal_gland | 1.58962221 |
35 | MP0002653_abnormal_ependyma_morphology | 1.55919044 |
36 | MP0003195_calcinosis | 1.54147247 |
37 | MP0003868_abnormal_feces_composition | 1.50280949 |
38 | MP0006054_spinal_hemorrhage | 1.49507525 |
39 | MP0005367_renal/urinary_system_phenotyp | 1.44415921 |
40 | MP0000516_abnormal_urinary_system | 1.44415921 |
41 | MP0000678_abnormal_parathyroid_gland | 1.43922884 |
42 | MP0003941_abnormal_skin_development | 1.39212757 |
43 | MP0005365_abnormal_bile_salt | 1.36835296 |
44 | MP0005408_hypopigmentation | 1.36094799 |
45 | MP0010352_gastrointestinal_tract_polyps | 1.33651433 |
46 | MP0004885_abnormal_endolymph | 1.32557105 |
47 | MP0005058_abnormal_lysosome_morphology | 1.31428151 |
48 | MP0009384_cardiac_valve_regurgitation | 1.31296107 |
49 | MP0004782_abnormal_surfactant_physiolog | 1.28082724 |
50 | MP0000534_abnormal_ureter_morphology | 1.27217046 |
51 | MP0003183_abnormal_peptide_metabolism | 1.26765881 |
52 | MP0005670_abnormal_white_adipose | 1.26733965 |
53 | MP0008875_abnormal_xenobiotic_pharmacok | 1.25746249 |
54 | MP0009764_decreased_sensitivity_to | 1.24765885 |
55 | MP0001664_abnormal_digestion | 1.24330477 |
56 | MP0003315_abnormal_perineum_morphology | 1.23150122 |
57 | MP0000377_abnormal_hair_follicle | 1.20712372 |
58 | MP0000627_abnormal_mammary_gland | 1.18350357 |
59 | MP0005083_abnormal_biliary_tract | 1.16493581 |
60 | MP0005360_urolithiasis | 1.15805440 |
61 | MP0000462_abnormal_digestive_system | 1.13566679 |
62 | MP0005645_abnormal_hypothalamus_physiol | 1.08982018 |
63 | MP0005381_digestive/alimentary_phenotyp | 1.08373268 |
64 | MP0002896_abnormal_bone_mineralization | 1.05811095 |
65 | MP0004272_abnormal_basement_membrane | 1.05320559 |
66 | MP0002060_abnormal_skin_morphology | 1.04203455 |
67 | MP0001984_abnormal_olfaction | 1.03321056 |
68 | MP0001663_abnormal_digestive_system | 1.02799964 |
69 | MP0005275_abnormal_skin_tensile | 1.02305128 |
70 | MP0000681_abnormal_thyroid_gland | 1.01467020 |
71 | MP0005501_abnormal_skin_physiology | 1.01005457 |
72 | MP0000566_synostosis | 0.99997447 |
73 | MP0003566_abnormal_cell_adhesion | 0.98248992 |
74 | MP0001216_abnormal_epidermal_layer | 0.97314059 |
75 | MP0000762_abnormal_tongue_morphology | 0.96704980 |
76 | MP0003866_abnormal_defecation | 0.96400119 |
77 | MP0002295_abnormal_pulmonary_circulatio | 0.90282770 |
78 | MP0002135_abnormal_kidney_morphology | 0.90011178 |
79 | MP0002876_abnormal_thyroid_physiology | 0.89190419 |
80 | MP0005395_other_phenotype | 0.89054089 |
81 | MP0005085_abnormal_gallbladder_physiolo | 0.89022145 |
82 | MP0003186_abnormal_redox_activity | 0.88734575 |
83 | MP0001958_emphysema | 0.88019445 |
84 | MP0000579_abnormal_nail_morphology | 0.87940859 |
85 | MP0010155_abnormal_intestine_physiology | 0.86539110 |
86 | MP0002138_abnormal_hepatobiliary_system | 0.86125027 |
87 | MP0003045_fibrosis | 0.85631376 |
88 | MP0000383_abnormal_hair_follicle | 0.85597488 |
89 | MP0005409_darkened_coat_color | 0.84757207 |
90 | MP0002254_reproductive_system_inflammat | 0.83629639 |
91 | MP0001299_abnormal_eye_distance/ | 0.83604958 |
92 | MP0001485_abnormal_pinna_reflex | 0.82333675 |
93 | MP0001188_hyperpigmentation | 0.81258940 |
94 | MP0008004_abnormal_stomach_pH | 0.81155307 |
95 | MP0009765_abnormal_xenobiotic_induced | 0.80833552 |
96 | MP0002132_abnormal_respiratory_system | 0.80511431 |
97 | MP0003453_abnormal_keratinocyte_physiol | 0.79574112 |
98 | MP0005319_abnormal_enzyme/_coenzyme | 0.79010274 |
99 | MP0005666_abnormal_adipose_tissue | 0.78530366 |
100 | MP0005187_abnormal_penis_morphology | 0.78270420 |
101 | MP0004147_increased_porphyrin_level | 0.78122711 |
102 | MP0001849_ear_inflammation | 0.77932972 |
103 | MP0010771_integument_phenotype | 0.76093144 |
104 | MP0000467_abnormal_esophagus_morphology | 0.75186998 |
105 | MP0003252_abnormal_bile_duct | 0.75186884 |
106 | MP0000230_abnormal_systemic_arterial | 0.74290557 |
107 | MP0002909_abnormal_adrenal_gland | 0.73874706 |
108 | MP0002168_other_aberrant_phenotype | 0.73195270 |
109 | MP0005248_abnormal_Harderian_gland | 0.72609182 |
110 | MP0000465_gastrointestinal_hemorrhage | 0.72268679 |
111 | MP0009053_abnormal_anal_canal | 0.72166739 |
112 | MP0005076_abnormal_cell_differentiation | 0.71194706 |
113 | MP0003936_abnormal_reproductive_system | 0.69281821 |
114 | MP0003656_abnormal_erythrocyte_physiolo | 0.68015269 |
115 | MP0000490_abnormal_crypts_of | 0.67766053 |
116 | MP0004947_skin_inflammation | 0.67045449 |
117 | MP0003638_abnormal_response/metabolism_ | 0.66708378 |
118 | MP0000470_abnormal_stomach_morphology | 0.66706391 |
119 | MP0000427_abnormal_hair_cycle | 0.66169881 |
120 | MP0004858_abnormal_nervous_system | 0.65191947 |
121 | MP0005023_abnormal_wound_healing | 0.64689018 |
122 | MP0004185_abnormal_adipocyte_glucose | 0.64480440 |
123 | MP0000477_abnormal_intestine_morphology | 0.62916109 |
124 | MP0002118_abnormal_lipid_homeostasis | 0.57265973 |
125 | MP0003718_maternal_effect | 0.56086634 |
126 | MP0008789_abnormal_olfactory_epithelium | 0.53834633 |
127 | MP0005166_decreased_susceptibility_to | 0.52377465 |
128 | MP0001270_distended_abdomen | 0.51568619 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 7.04376055 |
2 | Hyperactive renin-angiotensin system (HP:0000841) | 6.12610023 |
3 | Chronic bronchitis (HP:0004469) | 5.87415460 |
4 | Abnormal respiratory motile cilium physiology (HP:0012261) | 5.86160450 |
5 | Abnormal respiratory motile cilium morphology (HP:0005938) | 5.79186109 |
6 | Abnormal respiratory epithelium morphology (HP:0012253) | 5.79186109 |
7 | Hypokalemic alkalosis (HP:0001949) | 5.67009081 |
8 | Abnormality of chloride homeostasis (HP:0011422) | 5.62900658 |
9 | Absent/shortened dynein arms (HP:0200106) | 5.58014258 |
10 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 5.58014258 |
11 | Rhinitis (HP:0012384) | 5.55758889 |
12 | Abnormal ciliary motility (HP:0012262) | 5.54822586 |
13 | Metabolic alkalosis (HP:0200114) | 5.53515149 |
14 | Abnormality of cochlea (HP:0000375) | 5.53323224 |
15 | Hypomagnesemia (HP:0002917) | 5.48951190 |
16 | Increased circulating renin level (HP:0000848) | 5.01332577 |
17 | Abnormality of magnesium homeostasis (HP:0004921) | 4.60746025 |
18 | Decreased circulating renin level (HP:0003351) | 4.58460136 |
19 | Abnormality of renal excretion (HP:0011036) | 4.56534089 |
20 | Flat acetabular roof (HP:0003180) | 4.55651532 |
21 | Bronchiectasis (HP:0002110) | 4.47771704 |
22 | Abnormal urine output (HP:0012590) | 4.45754287 |
23 | Renal salt wasting (HP:0000127) | 4.29961888 |
24 | Polyuria (HP:0000103) | 4.15047625 |
25 | Hyperaldosteronism (HP:0000859) | 3.99102181 |
26 | Morphological abnormality of the inner ear (HP:0011390) | 3.95291936 |
27 | Gout (HP:0001997) | 3.76560301 |
28 | Hyperglycinuria (HP:0003108) | 3.60051701 |
29 | Aortic aneurysm (HP:0004942) | 3.57974100 |
30 | Potter facies (HP:0002009) | 3.56522937 |
31 | Facial shape deformation (HP:0011334) | 3.56522937 |
32 | Abnormal drinking behavior (HP:0030082) | 3.48926553 |
33 | Polydipsia (HP:0001959) | 3.48926553 |
34 | Nasal polyposis (HP:0100582) | 3.43410738 |
35 | Hypokalemia (HP:0002900) | 3.42083595 |
36 | Right ventricular cardiomyopathy (HP:0011663) | 3.41596018 |
37 | Vacuolated lymphocytes (HP:0001922) | 3.39396107 |
38 | Abnormality of renin-angiotensin system (HP:0000847) | 3.33959229 |
39 | Tetany (HP:0001281) | 3.32053295 |
40 | Bronchitis (HP:0012387) | 3.20378092 |
41 | Abnormality of the nasal mucosa (HP:0000433) | 3.16531413 |
42 | Hyperkalemia (HP:0002153) | 3.14984922 |
43 | Pili torti (HP:0003777) | 2.98523501 |
44 | Alkalosis (HP:0001948) | 2.94182389 |
45 | Abnormality of glycine metabolism (HP:0010895) | 2.70358534 |
46 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.70358534 |
47 | Onycholysis (HP:0001806) | 2.69341693 |
48 | Widely patent fontanelles and sutures (HP:0004492) | 2.68648414 |
49 | Abnormality of purine metabolism (HP:0004352) | 2.68077296 |
50 | Aortic dissection (HP:0002647) | 2.63052905 |
51 | Abnormality of potassium homeostasis (HP:0011042) | 2.61887813 |
52 | Rectal prolapse (HP:0002035) | 2.60319347 |
53 | Dehydration (HP:0001944) | 2.59047684 |
54 | Hypoplasia of the uterus (HP:0000013) | 2.58167177 |
55 | Infertility (HP:0000789) | 2.56279086 |
56 | Abnormality of the dental root (HP:0006486) | 2.52145769 |
57 | Taurodontia (HP:0000679) | 2.52145769 |
58 | Abnormality of permanent molar morphology (HP:0011071) | 2.52145769 |
59 | Flattened epiphyses (HP:0003071) | 2.48953117 |
60 | Male infertility (HP:0003251) | 2.45845967 |
61 | Shawl scrotum (HP:0000049) | 2.44368875 |
62 | Abnormality of the 2nd finger (HP:0004100) | 2.43619941 |
63 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.40025831 |
64 | Tubulointerstitial fibrosis (HP:0005576) | 2.39663974 |
65 | Recurrent otitis media (HP:0000403) | 2.39604411 |
66 | Chronic sinusitis (HP:0011109) | 2.32898751 |
67 | Spinal cord compression (HP:0002176) | 2.32423705 |
68 | Abnormality of fatty-acid metabolism (HP:0004359) | 2.31653997 |
69 | Neonatal short-limb short stature (HP:0008921) | 2.31336655 |
70 | Abnormality of molar morphology (HP:0011070) | 2.31077081 |
71 | Abnormality of molar (HP:0011077) | 2.31077081 |
72 | Lip pit (HP:0100267) | 2.30556542 |
73 | Proximal tubulopathy (HP:0000114) | 2.28222349 |
74 | Recurrent sinusitis (HP:0011108) | 2.28031761 |
75 | Abnormal foot bone ossification (HP:0010675) | 2.27172449 |
76 | Subcapsular cataract (HP:0000523) | 2.25561113 |
77 | Hyperuricemia (HP:0002149) | 2.23380773 |
78 | Increased purine levels (HP:0004368) | 2.23380773 |
79 | Abnormality of the dental pulp (HP:0006479) | 2.23129133 |
80 | Abnormality of carpal bone ossification (HP:0006257) | 2.21489107 |
81 | Ketoacidosis (HP:0001993) | 2.18904117 |
82 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.14440306 |
83 | Aplasia of the phalanges of the hand (HP:0009802) | 2.14440306 |
84 | Aplasia involving bones of the extremities (HP:0009825) | 2.14440306 |
85 | Abnormality of secondary sexual hair (HP:0009888) | 2.13351067 |
86 | Abnormality of the axillary hair (HP:0100134) | 2.13351067 |
87 | Glomerulosclerosis (HP:0000096) | 2.13082462 |
88 | Intrahepatic cholestasis (HP:0001406) | 2.11765573 |
89 | Hyperglycinemia (HP:0002154) | 2.09877863 |
90 | Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173) | 2.08946176 |
91 | Abdominal distention (HP:0003270) | 2.08734964 |
92 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.06442874 |
93 | Mucopolysacchariduria (HP:0008155) | 2.06442874 |
94 | Woolly hair (HP:0002224) | 2.05724542 |
95 | Malnutrition (HP:0004395) | 2.04459742 |
96 | Dysostosis multiplex (HP:0000943) | 2.01140799 |
97 | Hypoplastic labia majora (HP:0000059) | 1.99825386 |
98 | Hypercalciuria (HP:0002150) | 1.98046104 |
99 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 1.97864948 |
100 | Milia (HP:0001056) | 1.97535162 |
101 | Visceral angiomatosis (HP:0100761) | 1.94403824 |
102 | Abnormal tarsal ossification (HP:0008369) | 1.92662225 |
103 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.91552384 |
104 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.91552384 |
105 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.91552384 |
106 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.91346519 |
107 | Abnormality of proline metabolism (HP:0010907) | 1.90584887 |
108 | Hydroxyprolinuria (HP:0003080) | 1.90584887 |
109 | Hypotension (HP:0002615) | 1.90197714 |
110 | Abnormal hair laboratory examination (HP:0003328) | 1.89937700 |
111 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 1.88582546 |
112 | Abnormal vertebral ossification (HP:0100569) | 1.88067578 |
113 | Exocrine pancreatic insufficiency (HP:0001738) | 1.87200939 |
114 | Hypoplastic nipples (HP:0002557) | 1.86888362 |
115 | Short hallux (HP:0010109) | 1.85496476 |
116 | Hyponatremia (HP:0002902) | 1.84142052 |
117 | Abnormality of the intrinsic pathway (HP:0010989) | 1.83852975 |
118 | Vertebral hypoplasia (HP:0008417) | 1.83688088 |
119 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.83688088 |
120 | Tetraparesis (HP:0002273) | 1.83603054 |
121 | Atelectasis (HP:0100750) | 1.83011391 |
122 | Protuberant abdomen (HP:0001538) | 1.82657624 |
123 | Renal tubular acidosis (HP:0001947) | 1.81967694 |
124 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.80760410 |
125 | Ketosis (HP:0001946) | 1.80051579 |
126 | Abnormality of sodium homeostasis (HP:0010931) | 1.79792001 |
127 | Vascular calcification (HP:0004934) | 1.78429846 |
128 | Biliary tract neoplasm (HP:0100574) | 1.77883571 |
129 | Adrenal overactivity (HP:0002717) | 1.77656871 |
130 | Hemangiomatosis (HP:0007461) | 1.76246104 |
131 | Aplasia/hypoplasia of the femur (HP:0005613) | 1.76194000 |
132 | Abnormality of the labia majora (HP:0012881) | 1.75941696 |
133 | Abnormal cartilage morphology (HP:0002763) | 1.73927304 |
134 | Ureteral obstruction (HP:0006000) | 1.72410778 |
135 | Tubular atrophy (HP:0000092) | 1.72363676 |
136 | Wide cranial sutures (HP:0010537) | 1.71649768 |
137 | Long toe (HP:0010511) | 1.71319751 |
138 | Ureteral stenosis (HP:0000071) | 1.71189302 |
139 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.70589206 |
140 | Epiphyseal dysplasia (HP:0002656) | 1.70328771 |
141 | Abnormal hand bone ossification (HP:0010660) | 1.70305275 |
142 | Generalized aminoaciduria (HP:0002909) | 1.69550892 |
143 | Flat capital femoral epiphysis (HP:0003370) | 1.68928609 |
144 | Hyperphosphatemia (HP:0002905) | 1.67261293 |
145 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 1.66219936 |
146 | Thin bony cortex (HP:0002753) | 1.65992400 |
147 | Hypoplasia of the ulna (HP:0003022) | 1.65327514 |
148 | Abnormality of the 1st metacarpal (HP:0010009) | 1.65294728 |
149 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.64263695 |
150 | Short middle phalanx of finger (HP:0005819) | 1.60438611 |
151 | Amelogenesis imperfecta (HP:0000705) | 1.59286670 |
152 | Curly hair (HP:0002212) | 1.58976548 |
153 | Cone-rod dystrophy (HP:0000548) | 1.57950453 |
154 | Abnormal ossification of hand bones (HP:0005921) | 1.55936434 |
155 | Conjugated hyperbilirubinemia (HP:0002908) | 1.52848568 |
156 | Hypoplasia of dental enamel (HP:0006297) | 1.51656065 |
157 | Chondrocalcinosis (HP:0000934) | 1.48742797 |
158 | Cardiovascular calcification (HP:0011915) | 1.48322891 |
Rank | Gene Set | Z-score |
---|---|---|
1 | STK39 | 4.73225397 |
2 | MST4 | 4.71829384 |
3 | FRK | 4.46586413 |
4 | AKT3 | 4.39247189 |
5 | STK24 | 4.35082105 |
6 | MAPK15 | 4.07894934 |
7 | OXSR1 | 3.86782838 |
8 | LATS1 | 3.80058908 |
9 | ERN1 | 2.99979326 |
10 | WNK4 | 2.88726073 |
11 | TAOK3 | 2.83666092 |
12 | BCKDK | 2.79878598 |
13 | EEF2K | 2.57912351 |
14 | PDK2 | 2.27660294 |
15 | SIK1 | 2.26633953 |
16 | MYLK | 2.21483567 |
17 | ACVR1B | 2.06568909 |
18 | MST1R | 2.03849947 |
19 | LMTK2 | 1.98684542 |
20 | MAP3K2 | 1.96283307 |
21 | MAPKAPK3 | 1.85264053 |
22 | NUAK1 | 1.64318869 |
23 | WNK3 | 1.59553049 |
24 | LRRK2 | 1.56121941 |
25 | SMG1 | 1.54548321 |
26 | TTN | 1.50776372 |
27 | SCYL2 | 1.46446091 |
28 | STK38L | 1.44656455 |
29 | RPS6KB2 | 1.37474809 |
30 | PTK6 | 1.37099218 |
31 | FER | 1.35046316 |
32 | BRSK2 | 1.34922443 |
33 | TRIB3 | 1.29330928 |
34 | EPHA2 | 1.24501817 |
35 | EPHB2 | 1.17343957 |
36 | PIK3CA | 1.12397877 |
37 | STK10 | 1.12119518 |
38 | ICK | 1.10775669 |
39 | DDR2 | 1.03486704 |
40 | TRPM7 | 1.02277750 |
41 | PKN2 | 1.01901255 |
42 | PIK3CG | 0.98450593 |
43 | MARK2 | 0.97886551 |
44 | MET | 0.92154785 |
45 | MAP3K3 | 0.89104823 |
46 | MAP2K2 | 0.88175678 |
47 | BCR | 0.85510142 |
48 | PDK3 | 0.84584220 |
49 | PDK4 | 0.84584220 |
50 | STK3 | 0.84524990 |
51 | SGK2 | 0.81970389 |
52 | ARAF | 0.81485248 |
53 | SGK223 | 0.79717307 |
54 | SGK494 | 0.79717307 |
55 | PRKD2 | 0.79233631 |
56 | SGK3 | 0.78436576 |
57 | PIM2 | 0.76777060 |
58 | MAP3K12 | 0.74881783 |
59 | RIPK4 | 0.71249925 |
60 | TNK2 | 0.68163546 |
61 | NEK6 | 0.67662773 |
62 | PRKG2 | 0.67625733 |
63 | TESK1 | 0.67323559 |
64 | DMPK | 0.66528286 |
65 | NLK | 0.65995038 |
66 | ILK | 0.64941627 |
67 | STK38 | 0.64798528 |
68 | PAK2 | 0.64285118 |
69 | INSRR | 0.64207525 |
70 | PRKCI | 0.62477638 |
71 | CAMKK2 | 0.59964743 |
72 | EPHA3 | 0.56344071 |
73 | DAPK2 | 0.56131947 |
74 | WNK1 | 0.54503860 |
75 | ERBB3 | 0.53000358 |
76 | RIPK1 | 0.51154446 |
77 | CAMK1D | 0.48796445 |
78 | PTK2 | 0.47894330 |
79 | IRAK1 | 0.46167258 |
80 | MAPK7 | 0.45960774 |
81 | PDGFRB | 0.45907528 |
82 | JAK2 | 0.45160521 |
83 | RPS6KA2 | 0.44936973 |
84 | PDGFRA | 0.44792847 |
85 | MAP3K7 | 0.43047969 |
86 | SGK1 | 0.41689739 |
87 | ROCK1 | 0.40968491 |
88 | LATS2 | 0.40717565 |
89 | FGFR2 | 0.39002469 |
90 | PDPK1 | 0.37998869 |
91 | YES1 | 0.37165204 |
92 | PAK4 | 0.36927992 |
93 | RPS6KB1 | 0.36462417 |
94 | ROCK2 | 0.34864343 |
95 | JAK3 | 0.34323022 |
96 | TTK | 0.33389992 |
97 | TESK2 | 0.33374688 |
98 | KSR2 | 0.32968527 |
99 | MAP2K6 | 0.32441711 |
100 | CSNK1A1 | 0.32419510 |
101 | PRKAA1 | 0.32148697 |
102 | IGF1R | 0.31784392 |
103 | PRKCE | 0.31690588 |
104 | CHUK | 0.30168623 |
105 | MAPK12 | 0.29684010 |
106 | CAMK1G | 0.29553908 |
107 | EPHB1 | 0.28622524 |
108 | GRK1 | 0.28160953 |
109 | CAMKK1 | 0.27832035 |
110 | RET | 0.27594588 |
111 | MAP2K1 | 0.26782844 |
112 | ERBB2 | 0.24427176 |
113 | PRKCD | 0.24261712 |
114 | MTOR | 0.24023783 |
115 | MAP3K8 | 0.24002276 |
116 | PDK1 | 0.23765166 |
117 | TYK2 | 0.22784372 |
118 | CSK | 0.22043328 |
119 | GSK3A | 0.20147268 |
120 | PRKAA2 | 0.18669224 |
121 | PRKD3 | 0.18487972 |
122 | PRKCA | 0.17101690 |
123 | MELK | 0.16147104 |
124 | NTRK1 | 0.15225479 |
125 | TAOK1 | 0.15201703 |
126 | TGFBR1 | 0.15069693 |
127 | PRKD1 | 0.14972464 |
128 | MAP3K13 | 0.14934558 |
129 | BMX | 0.14741098 |
130 | JAK1 | 0.14686778 |
131 | PAK3 | 0.14508295 |
132 | TGFBR2 | 0.14469461 |
133 | MINK1 | 0.13947627 |
134 | CAMK2G | 0.13876700 |
135 | NME1 | 0.08996014 |
136 | MATK | 0.08834363 |
137 | RPS6KL1 | 0.08429277 |
138 | RPS6KC1 | 0.08429277 |
139 | EGFR | 0.08293038 |
140 | FGFR3 | 0.08250598 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Nitrogen metabolism_Homo sapiens_hsa00910 | 4.41791162 |
2 | Sulfur metabolism_Homo sapiens_hsa00920 | 4.35567199 |
3 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 3.93967626 |
4 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 2.86372389 |
5 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.51024251 |
6 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 2.46974630 |
7 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.40312092 |
8 | Protein export_Homo sapiens_hsa03060 | 2.31364306 |
9 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 2.22654795 |
10 | Protein digestion and absorption_Homo sapiens_hsa04974 | 2.15676877 |
11 | Other glycan degradation_Homo sapiens_hsa00511 | 2.10892045 |
12 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 2.00887635 |
13 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.98862359 |
14 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 1.97319028 |
15 | Fatty acid degradation_Homo sapiens_hsa00071 | 1.87731471 |
16 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.78240121 |
17 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.71667742 |
18 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.70252673 |
19 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.65649422 |
20 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.63091906 |
21 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.61120392 |
22 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.60781459 |
23 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.56015115 |
24 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.54243131 |
25 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.52741978 |
26 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.46979552 |
27 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.44049618 |
28 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.43731652 |
29 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.42689543 |
30 | Retinol metabolism_Homo sapiens_hsa00830 | 1.37726183 |
31 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.33178137 |
32 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.30448787 |
33 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.25080163 |
34 | Bladder cancer_Homo sapiens_hsa05219 | 1.21521149 |
35 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.21098515 |
36 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.18785976 |
37 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 1.14609356 |
38 | ECM-receptor interaction_Homo sapiens_hsa04512 | 1.14370600 |
39 | Mineral absorption_Homo sapiens_hsa04978 | 1.09611307 |
40 | * Tight junction_Homo sapiens_hsa04530 | 1.08976384 |
41 | Gastric acid secretion_Homo sapiens_hsa04971 | 1.08011130 |
42 | Adherens junction_Homo sapiens_hsa04520 | 1.07594264 |
43 | Prostate cancer_Homo sapiens_hsa05215 | 1.07388247 |
44 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.07058102 |
45 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.04549890 |
46 | Sulfur relay system_Homo sapiens_hsa04122 | 1.03385744 |
47 | Endometrial cancer_Homo sapiens_hsa05213 | 1.03055018 |
48 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.97748104 |
49 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.92695778 |
50 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.90902884 |
51 | Lysosome_Homo sapiens_hsa04142 | 0.90221023 |
52 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.90078632 |
53 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.89984017 |
54 | Focal adhesion_Homo sapiens_hsa04510 | 0.89539366 |
55 | Peroxisome_Homo sapiens_hsa04146 | 0.87901878 |
56 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.81840612 |
57 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.81412531 |
58 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.81025746 |
59 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.80835335 |
60 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.80708655 |
61 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.80264990 |
62 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.78752926 |
63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.77112432 |
64 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.74100877 |
65 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.72757882 |
66 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.71467994 |
67 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.71256634 |
68 | Amoebiasis_Homo sapiens_hsa05146 | 0.70773052 |
69 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.70328086 |
70 | Insulin resistance_Homo sapiens_hsa04931 | 0.68893382 |
71 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.68529393 |
72 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.67684679 |
73 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.67425599 |
74 | Circadian rhythm_Homo sapiens_hsa04710 | 0.66975776 |
75 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.66106303 |
76 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.64626294 |
77 | Bile secretion_Homo sapiens_hsa04976 | 0.63498951 |
78 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.63226517 |
79 | ABC transporters_Homo sapiens_hsa02010 | 0.63119131 |
80 | Galactose metabolism_Homo sapiens_hsa00052 | 0.60649233 |
81 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.59971786 |
82 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.59954947 |
83 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.58003794 |
84 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.54654640 |
85 | Renin secretion_Homo sapiens_hsa04924 | 0.53923873 |
86 | Histidine metabolism_Homo sapiens_hsa00340 | 0.51892617 |
87 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.50585049 |
88 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.50283923 |
89 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.50045418 |
90 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.49556704 |
91 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 0.48878795 |
92 | Carbon metabolism_Homo sapiens_hsa01200 | 0.47525745 |
93 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.47452108 |
94 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.47328777 |
95 | Thyroid cancer_Homo sapiens_hsa05216 | 0.46909883 |
96 | * Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.46500485 |
97 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.45472043 |
98 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.44021078 |
99 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.43954487 |
100 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.43367862 |
101 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.43196351 |
102 | Lysine degradation_Homo sapiens_hsa00310 | 0.41995592 |
103 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.41919209 |
104 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.41688163 |
105 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.41488825 |
106 | Melanoma_Homo sapiens_hsa05218 | 0.40752603 |
107 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.39691568 |
108 | * Hepatitis C_Homo sapiens_hsa05160 | 0.39276407 |
109 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.37988204 |
110 | Salivary secretion_Homo sapiens_hsa04970 | 0.37622160 |
111 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.36488812 |
112 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.34227209 |
113 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.33740745 |
114 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.33583382 |
115 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.32953084 |
116 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.32635397 |
117 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.32049466 |
118 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.31019869 |
119 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.28170016 |
120 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.27229520 |
121 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.25607428 |
122 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.24301933 |
123 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.21289464 |
124 | Metabolic pathways_Homo sapiens_hsa01100 | 0.21139713 |
125 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.21055369 |
126 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.18986433 |
127 | Endocytosis_Homo sapiens_hsa04144 | 0.14020178 |
128 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.12196603 |
129 | Huntingtons disease_Homo sapiens_hsa05016 | 0.10103447 |
130 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.08500376 |
131 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.07921623 |