

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of B cell receptor signaling pathway (GO:0050855) | 7.42614348 |
| 2 | B cell receptor signaling pathway (GO:0050853) | 6.76592599 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.80842664 |
| 4 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.62137959 |
| 5 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.62137959 |
| 6 | modulation by symbiont of host immune response (GO:0052553) | 5.62137959 |
| 7 | positive regulation by symbiont of host defense response (GO:0052509) | 5.62137959 |
| 8 | modulation by symbiont of host defense response (GO:0052031) | 5.62137959 |
| 9 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.62137959 |
| 10 | antigen processing and presentation of endogenous antigen (GO:0019883) | 5.33080466 |
| 11 | immunoglobulin mediated immune response (GO:0016064) | 5.30883435 |
| 12 | regulation of interferon-beta biosynthetic process (GO:0045357) | 5.11201412 |
| 13 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 5.00290814 |
| 14 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.94211411 |
| 15 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 4.92526583 |
| 16 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 4.86746569 |
| 17 | antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885) | 4.69647529 |
| 18 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 4.54913668 |
| 19 | B cell proliferation (GO:0042100) | 4.51238553 |
| 20 | B cell homeostasis (GO:0001782) | 4.50649727 |
| 21 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.50268558 |
| 22 | regulation of B cell differentiation (GO:0045577) | 4.48340721 |
| 23 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 4.40852833 |
| 24 | negative regulation of cell killing (GO:0031342) | 4.38449842 |
| 25 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.38449842 |
| 26 | positive regulation of B cell differentiation (GO:0045579) | 4.35642979 |
| 27 | interferon-gamma-mediated signaling pathway (GO:0060333) | 4.35152923 |
| 28 | B cell mediated immunity (GO:0019724) | 4.34857800 |
| 29 | macrophage activation involved in immune response (GO:0002281) | 4.34340094 |
| 30 | regulation of gamma-delta T cell activation (GO:0046643) | 4.32473383 |
| 31 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.22015913 |
| 32 | negative thymic T cell selection (GO:0045060) | 4.20701100 |
| 33 | NIK/NF-kappaB signaling (GO:0038061) | 4.18915754 |
| 34 | T cell migration (GO:0072678) | 4.15035762 |
| 35 | positive thymic T cell selection (GO:0045059) | 4.12999930 |
| 36 | detection of bacterium (GO:0016045) | 4.12939105 |
| 37 | defense response to protozoan (GO:0042832) | 4.08471410 |
| 38 | cellular response to type I interferon (GO:0071357) | 4.03954891 |
| 39 | type I interferon signaling pathway (GO:0060337) | 4.03954891 |
| 40 | response to type I interferon (GO:0034340) | 4.02558159 |
| 41 | cellular response to interleukin-15 (GO:0071350) | 3.96962700 |
| 42 | negative T cell selection (GO:0043383) | 3.96644307 |
| 43 | regulation of antigen processing and presentation (GO:0002577) | 3.96378674 |
| 44 | detection of other organism (GO:0098543) | 3.94240765 |
| 45 | negative regulation of B cell proliferation (GO:0030889) | 3.93813822 |
| 46 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.92093887 |
| 47 | T-helper 1 type immune response (GO:0042088) | 3.89188020 |
| 48 | response to host immune response (GO:0052572) | 3.88452832 |
| 49 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 3.88452832 |
| 50 | positive regulation of interferon-alpha production (GO:0032727) | 3.85349512 |
| 51 | positive regulation of humoral immune response (GO:0002922) | 3.82392040 |
| 52 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 3.77550614 |
| 53 | response to protozoan (GO:0001562) | 3.75092601 |
| 54 | regulation of alpha-beta T cell proliferation (GO:0046640) | 3.73117788 |
| 55 | regulation of B cell proliferation (GO:0030888) | 3.71204533 |
| 56 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.69706019 |
| 57 | response to interleukin-15 (GO:0070672) | 3.69027102 |
| 58 | regulation of interferon-alpha production (GO:0032647) | 3.62585494 |
| 59 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.59485417 |
| 60 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.57930405 |
| 61 | positive T cell selection (GO:0043368) | 3.54452852 |
| 62 | thymic T cell selection (GO:0045061) | 3.54289424 |
| 63 | regulation of gamma-delta T cell differentiation (GO:0045586) | 3.46474116 |
| 64 | T cell costimulation (GO:0031295) | 3.44390543 |
| 65 | cytidine metabolic process (GO:0046087) | 3.44090880 |
| 66 | cytidine catabolic process (GO:0006216) | 3.44090880 |
| 67 | cytidine deamination (GO:0009972) | 3.44090880 |
| 68 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.43435654 |
| 69 | response to host (GO:0075136) | 3.43435654 |
| 70 | response to host defenses (GO:0052200) | 3.43435654 |
| 71 | positive regulation of B cell proliferation (GO:0030890) | 3.40190032 |
| 72 | lymphocyte costimulation (GO:0031294) | 3.39305689 |
| 73 | T cell lineage commitment (GO:0002360) | 3.38144950 |
| 74 | germinal center formation (GO:0002467) | 3.33069269 |
| 75 | T cell selection (GO:0045058) | 3.32969676 |
| 76 | regulation of germinal center formation (GO:0002634) | 3.24796482 |
| 77 | positive regulation of B cell activation (GO:0050871) | 3.24257260 |
| 78 | lymphocyte homeostasis (GO:0002260) | 3.23253662 |
| 79 | negative regulation of phagocytosis (GO:0050765) | 3.21574023 |
| 80 | negative regulation of alpha-beta T cell activation (GO:0046636) | 3.19814974 |
| 81 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.18808933 |
| 82 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.18804512 |
| 83 | cellular response to interferon-gamma (GO:0071346) | 3.16725426 |
| 84 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 3.15623347 |
| 85 | positive regulation of antigen processing and presentation (GO:0002579) | 3.14913218 |
| 86 | detection of external biotic stimulus (GO:0098581) | 3.14319878 |
| 87 | microglial cell activation (GO:0001774) | 3.12970175 |
| 88 | positive regulation of B cell mediated immunity (GO:0002714) | 3.09237756 |
| 89 | positive regulation of immunoglobulin mediated immune response (GO:0002891) | 3.09237756 |
| 90 | regulation of B cell activation (GO:0050864) | 3.09096163 |
| 91 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 3.06533813 |
| 92 | adaptive immune response based on somatic recombination of immune receptors built from immunoglobuli | 3.03972347 |
| 93 | negative regulation of calcium ion transport into cytosol (GO:0010523) | 3.01559142 |
| 94 | negative regulation of T cell mediated immunity (GO:0002710) | 2.98022130 |
| 95 | positive regulation of interferon-beta production (GO:0032728) | 2.98012099 |
| 96 | regulation of B cell apoptotic process (GO:0002902) | 2.97822999 |
| 97 | positive regulation of cytokine biosynthetic process (GO:0042108) | 2.96347388 |
| 98 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 2.91428151 |
| 99 | mature B cell differentiation (GO:0002335) | 2.89492055 |
| 100 | regulation of interferon-beta production (GO:0032648) | 2.87149083 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 7.78648141 |
| 2 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 4.52355530 |
| 3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.33115449 |
| 4 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.07498287 |
| 5 | MYC_22102868_ChIP-Seq_BL_Human | 3.95219285 |
| 6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.90111815 |
| 7 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 3.77060359 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.57128970 |
| 9 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 3.15276989 |
| 10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.12128476 |
| 11 | MYB_26560356_Chip-Seq_TH2_Human | 2.95778358 |
| 12 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.90621202 |
| 13 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 2.80698710 |
| 14 | CIITA_25753668_ChIP-Seq_RAJI_Human | 2.78527856 |
| 15 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 2.73867659 |
| 16 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.68295284 |
| 17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.66164324 |
| 18 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.62772864 |
| 19 | MYB_26560356_Chip-Seq_TH1_Human | 2.57261954 |
| 20 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.40784627 |
| 21 | MAF_26560356_Chip-Seq_TH1_Human | 2.40507403 |
| 22 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.35276790 |
| 23 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.24843204 |
| 24 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.15447371 |
| 25 | GATA1_22025678_ChIP-Seq_K562_Human | 2.11915440 |
| 26 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 2.11634661 |
| 27 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.11000454 |
| 28 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.01319899 |
| 29 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.99924906 |
| 30 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.95911798 |
| 31 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.90968122 |
| 32 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.89761729 |
| 33 | UTX_26944678_Chip-Seq_JUKART_Human | 1.85362625 |
| 34 | GATA3_26560356_Chip-Seq_TH2_Human | 1.83930907 |
| 35 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.80168030 |
| 36 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.76388343 |
| 37 | MAF_26560356_Chip-Seq_TH2_Human | 1.65023482 |
| 38 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.64055815 |
| 39 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63057722 |
| 40 | SPI1_23127762_ChIP-Seq_K562_Human | 1.61173515 |
| 41 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.59671293 |
| 42 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.53067380 |
| 43 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.51609656 |
| 44 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.51599895 |
| 45 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51353977 |
| 46 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.49705258 |
| 47 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.48717568 |
| 48 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.47279689 |
| 49 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.46183375 |
| 50 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.42637168 |
| 51 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.42533233 |
| 52 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.35773618 |
| 53 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.32922101 |
| 54 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.27535775 |
| 55 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.27238985 |
| 56 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.26745318 |
| 57 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.25428754 |
| 58 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.19305785 |
| 59 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.14837085 |
| 60 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.12061309 |
| 61 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.11724426 |
| 62 | GATA3_26560356_Chip-Seq_TH1_Human | 1.08333892 |
| 63 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.06596463 |
| 64 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.04451363 |
| 65 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.03349522 |
| 66 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.01776052 |
| 67 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.00482701 |
| 68 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.98317584 |
| 69 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.97568163 |
| 70 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.97484044 |
| 71 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 0.96290494 |
| 72 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.95656608 |
| 73 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.95132446 |
| 74 | BCL6_27268052_Chip-Seq_Bcells_Human | 0.94428219 |
| 75 | * GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.94016216 |
| 76 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.93705737 |
| 77 | PU_27001747_Chip-Seq_BMDM_Mouse | 0.92719135 |
| 78 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.91679596 |
| 79 | P300_27268052_Chip-Seq_Bcells_Human | 0.89944686 |
| 80 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.88532301 |
| 81 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.87476066 |
| 82 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 0.87410501 |
| 83 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 0.86437417 |
| 84 | * ZNF274_21170338_ChIP-Seq_K562_Hela | 0.85814892 |
| 85 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.81762841 |
| 86 | * GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.81417561 |
| 87 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.81290706 |
| 88 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.80691061 |
| 89 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.79371494 |
| 90 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.79371049 |
| 91 | BCL6_25482012_ChIP-Seq_CML-JURL-MK1_Human | 0.78605446 |
| 92 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.75142003 |
| 93 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 0.74739988 |
| 94 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.74616388 |
| 95 | SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human | 0.73166215 |
| 96 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 0.73037104 |
| 97 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.71495971 |
| 98 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.69435861 |
| 99 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.68965348 |
| 100 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.66622078 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001835_abnormal_antigen_presentation | 4.52750773 |
| 2 | MP0005671_abnormal_response_to | 4.49576309 |
| 3 | MP0000685_abnormal_immune_system | 4.47090876 |
| 4 | MP0001800_abnormal_humoral_immune | 4.19985341 |
| 5 | MP0001790_abnormal_immune_system | 4.08146747 |
| 6 | MP0005387_immune_system_phenotype | 4.08146747 |
| 7 | MP0002138_abnormal_hepatobiliary_system | 3.29254063 |
| 8 | MP0005000_abnormal_immune_tolerance | 3.25892119 |
| 9 | MP0002452_abnormal_antigen_presenting | 3.10355920 |
| 10 | MP0002723_abnormal_immune_serum | 3.07686745 |
| 11 | MP0003763_abnormal_thymus_physiology | 2.97002220 |
| 12 | MP0003303_peritoneal_inflammation | 2.91058610 |
| 13 | MP0002420_abnormal_adaptive_immunity | 2.86037292 |
| 14 | MP0001819_abnormal_immune_cell | 2.79574666 |
| 15 | MP0002398_abnormal_bone_marrow | 2.50590231 |
| 16 | MP0003436_decreased_susceptibility_to | 2.42104977 |
| 17 | MP0005025_abnormal_response_to | 2.36331424 |
| 18 | MP0009785_altered_susceptibility_to | 2.34829332 |
| 19 | MP0000716_abnormal_immune_system | 2.34730502 |
| 20 | MP0005645_abnormal_hypothalamus_physiol | 2.34597033 |
| 21 | MP0005310_abnormal_salivary_gland | 2.34461046 |
| 22 | MP0000689_abnormal_spleen_morphology | 2.14986158 |
| 23 | MP0002419_abnormal_innate_immunity | 2.10815095 |
| 24 | MP0003183_abnormal_peptide_metabolism | 2.10058473 |
| 25 | MP0002166_altered_tumor_susceptibility | 2.03329225 |
| 26 | MP0002148_abnormal_hypersensitivity_rea | 2.02549970 |
| 27 | MP0003724_increased_susceptibility_to | 1.88705450 |
| 28 | MP0002429_abnormal_blood_cell | 1.85330665 |
| 29 | MP0005075_abnormal_melanosome_morpholog | 1.82588108 |
| 30 | MP0002722_abnormal_immune_system | 1.80708303 |
| 31 | MP0002405_respiratory_system_inflammati | 1.76187136 |
| 32 | MP0001845_abnormal_inflammatory_respons | 1.67637786 |
| 33 | MP0010155_abnormal_intestine_physiology | 1.56305573 |
| 34 | MP0000703_abnormal_thymus_morphology | 1.54270994 |
| 35 | MP0004381_abnormal_hair_follicle | 1.50801412 |
| 36 | MP0008057_abnormal_DNA_replication | 1.45964004 |
| 37 | MP0001873_stomach_inflammation | 1.44028171 |
| 38 | MP0000372_irregular_coat_pigmentation | 1.43288875 |
| 39 | MP0009333_abnormal_splenocyte_physiolog | 1.41344568 |
| 40 | MP0002006_tumorigenesis | 1.40846065 |
| 41 | MP0000015_abnormal_ear_pigmentation | 1.40749948 |
| 42 | MP0000569_abnormal_digit_pigmentation | 1.38958538 |
| 43 | MP0002396_abnormal_hematopoietic_system | 1.36711172 |
| 44 | MP0003300_gastrointestinal_ulcer | 1.34167506 |
| 45 | MP0002928_abnormal_bile_duct | 1.32799355 |
| 46 | MP0003045_fibrosis | 1.31433424 |
| 47 | MP0002163_abnormal_gland_morphology | 1.26508071 |
| 48 | MP0003787_abnormal_imprinting | 1.25143456 |
| 49 | MP0001348_abnormal_lacrimal_gland | 1.23124766 |
| 50 | MP0005464_abnormal_platelet_physiology | 1.18504647 |
| 51 | MP0008877_abnormal_DNA_methylation | 1.14466994 |
| 52 | MP0008469_abnormal_protein_level | 1.09897871 |
| 53 | MP0003172_abnormal_lysosome_physiology | 1.07640583 |
| 54 | MP0003252_abnormal_bile_duct | 0.98834752 |
| 55 | MP0003866_abnormal_defecation | 0.96344610 |
| 56 | MP0000371_diluted_coat_color | 0.96212314 |
| 57 | MP0002693_abnormal_pancreas_physiology | 0.96096003 |
| 58 | MP0004947_skin_inflammation | 0.95707531 |
| 59 | MP0003646_muscle_fatigue | 0.95568771 |
| 60 | MP0008872_abnormal_physiological_respon | 0.93802132 |
| 61 | MP0001986_abnormal_taste_sensitivity | 0.88601587 |
| 62 | MP0002019_abnormal_tumor_incidence | 0.87919457 |
| 63 | MP0009764_decreased_sensitivity_to | 0.85295225 |
| 64 | MP0001853_heart_inflammation | 0.84943221 |
| 65 | MP0005379_endocrine/exocrine_gland_phen | 0.83145627 |
| 66 | MP0006082_CNS_inflammation | 0.79877956 |
| 67 | MP0001533_abnormal_skeleton_physiology | 0.77238482 |
| 68 | MP0005451_abnormal_body_composition | 0.75844135 |
| 69 | MP0002009_preneoplasia | 0.73666699 |
| 70 | MP0001545_abnormal_hematopoietic_system | 0.69008930 |
| 71 | MP0005397_hematopoietic_system_phenotyp | 0.69008930 |
| 72 | MP0002095_abnormal_skin_pigmentation | 0.68536774 |
| 73 | MP0000465_gastrointestinal_hemorrhage | 0.67384835 |
| 74 | MP0010094_abnormal_chromosome_stability | 0.66539698 |
| 75 | MP0002254_reproductive_system_inflammat | 0.65219698 |
| 76 | MP0001663_abnormal_digestive_system | 0.63586822 |
| 77 | MP0002136_abnormal_kidney_physiology | 0.63385247 |
| 78 | MP0004808_abnormal_hematopoietic_stem | 0.63260160 |
| 79 | MP0004883_abnormal_blood_vessel | 0.62830127 |
| 80 | MP0006035_abnormal_mitochondrial_morpho | 0.62296739 |
| 81 | MP0002132_abnormal_respiratory_system | 0.61045976 |
| 82 | MP0005174_abnormal_tail_pigmentation | 0.55264750 |
| 83 | MP0008874_decreased_physiological_sensi | 0.54999595 |
| 84 | MP0002933_joint_inflammation | 0.54673151 |
| 85 | MP0009763_increased_sensitivity_to | 0.53756552 |
| 86 | MP0008260_abnormal_autophagy | 0.53116418 |
| 87 | MP0004510_myositis | 0.52826778 |
| 88 | MP0002653_abnormal_ependyma_morphology | 0.50963188 |
| 89 | MP0003656_abnormal_erythrocyte_physiolo | 0.49967440 |
| 90 | MP0008058_abnormal_DNA_repair | 0.48605945 |
| 91 | MP0002277_abnormal_respiratory_mucosa | 0.47994351 |
| 92 | MP0009278_abnormal_bone_marrow | 0.47176822 |
| 93 | MP0009115_abnormal_fat_cell | 0.46773707 |
| 94 | MP0000858_altered_metastatic_potential | 0.46674325 |
| 95 | MP0008961_abnormal_basal_metabolism | 0.46342457 |
| 96 | MP0009765_abnormal_xenobiotic_induced | 0.46341262 |
| 97 | MP0002168_other_aberrant_phenotype | 0.46080212 |
| 98 | MP0000249_abnormal_blood_vessel | 0.46065255 |
| 99 | MP0004142_abnormal_muscle_tone | 0.45968113 |
| 100 | MP0000490_abnormal_crypts_of | 0.43967527 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Gastrointestinal stroma tumor (HP:0100723) | 7.41996872 |
| 2 | Agammaglobulinemia (HP:0004432) | 7.36632337 |
| 3 | Recurrent sinusitis (HP:0011108) | 6.07524675 |
| 4 | Recurrent bronchitis (HP:0002837) | 5.33664719 |
| 5 | Meningitis (HP:0001287) | 5.29440767 |
| 6 | Lymphopenia (HP:0001888) | 5.12843467 |
| 7 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 4.99899025 |
| 8 | Vasculitis (HP:0002633) | 4.84485193 |
| 9 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 4.73859261 |
| 10 | Panhypogammaglobulinemia (HP:0003139) | 4.68983604 |
| 11 | Mediastinal lymphadenopathy (HP:0100721) | 4.55492164 |
| 12 | IgM deficiency (HP:0002850) | 4.49565166 |
| 13 | IgA deficiency (HP:0002720) | 4.32744967 |
| 14 | Recurrent viral infections (HP:0004429) | 4.23293379 |
| 15 | Cellulitis (HP:0100658) | 4.22863103 |
| 16 | Colitis (HP:0002583) | 4.13170640 |
| 17 | Recurrent bacterial skin infections (HP:0005406) | 4.08618760 |
| 18 | Recurrent cutaneous fungal infections (HP:0011370) | 4.01384564 |
| 19 | Chronic mucocutaneous candidiasis (HP:0002728) | 4.01384564 |
| 20 | Emphysema (HP:0002097) | 3.93829528 |
| 21 | IgG deficiency (HP:0004315) | 3.87181994 |
| 22 | Recurrent fungal infections (HP:0002841) | 3.86252930 |
| 23 | Recurrent pneumonia (HP:0006532) | 3.78510486 |
| 24 | Eczematoid dermatitis (HP:0000976) | 3.75849892 |
| 25 | Verrucae (HP:0200043) | 3.74251886 |
| 26 | Papilloma (HP:0012740) | 3.74251886 |
| 27 | Recurrent abscess formation (HP:0002722) | 3.66865609 |
| 28 | Inflammation of the large intestine (HP:0002037) | 3.53728883 |
| 29 | Recurrent lower respiratory tract infections (HP:0002783) | 3.52079908 |
| 30 | Abnormality of T cell physiology (HP:0011840) | 3.50529203 |
| 31 | Restrictive lung disease (HP:0002091) | 3.50063892 |
| 32 | Encephalitis (HP:0002383) | 3.46297183 |
| 33 | Gastrointestinal inflammation (HP:0004386) | 3.39236824 |
| 34 | Osteomyelitis (HP:0002754) | 3.29317651 |
| 35 | Chronic diarrhea (HP:0002028) | 3.27734931 |
| 36 | Retrobulbar optic neuritis (HP:0100654) | 3.26557751 |
| 37 | Optic neuritis (HP:0100653) | 3.26557751 |
| 38 | Recurrent skin infections (HP:0001581) | 3.21517536 |
| 39 | Abnormality of B cell number (HP:0010975) | 3.18459150 |
| 40 | Pulmonary infiltrates (HP:0002113) | 3.15594524 |
| 41 | Chronic otitis media (HP:0000389) | 3.10799990 |
| 42 | Bronchitis (HP:0012387) | 3.04344401 |
| 43 | Abnormality of T cells (HP:0002843) | 3.03576413 |
| 44 | Abnormality of macrophages (HP:0004311) | 2.97366418 |
| 45 | B lymphocytopenia (HP:0010976) | 2.96956937 |
| 46 | Urticaria (HP:0001025) | 2.96008729 |
| 47 | Lymphoma (HP:0002665) | 2.91868563 |
| 48 | Obstructive lung disease (HP:0006536) | 2.85369098 |
| 49 | Chronic obstructive pulmonary disease (HP:0006510) | 2.85369098 |
| 50 | Chronic sinusitis (HP:0011109) | 2.81584594 |
| 51 | Sepsis (HP:0100806) | 2.80987143 |
| 52 | Viral hepatitis (HP:0006562) | 2.77974877 |
| 53 | Increased IgM level (HP:0003496) | 2.77313972 |
| 54 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.73989133 |
| 55 | Orchitis (HP:0100796) | 2.73547645 |
| 56 | Abnormality of the prostate (HP:0008775) | 2.69606201 |
| 57 | Leukopenia (HP:0001882) | 2.69498564 |
| 58 | Gastrointestinal infarctions (HP:0005244) | 2.63047830 |
| 59 | Basal cell carcinoma (HP:0002671) | 2.62545221 |
| 60 | Myositis (HP:0100614) | 2.58483682 |
| 61 | Recurrent otitis media (HP:0000403) | 2.57718220 |
| 62 | Skin rash (HP:0000988) | 2.54434078 |
| 63 | Chest pain (HP:0100749) | 2.47964767 |
| 64 | Increased IgE level (HP:0003212) | 2.41732813 |
| 65 | Abnormality of T cell number (HP:0011839) | 2.36383558 |
| 66 | Neutropenia (HP:0001875) | 2.33752093 |
| 67 | Hemoptysis (HP:0002105) | 2.29573606 |
| 68 | Abnormality of the pleura (HP:0002103) | 2.27848027 |
| 69 | Keratoconjunctivitis sicca (HP:0001097) | 2.18997535 |
| 70 | Arthralgia (HP:0002829) | 2.18514465 |
| 71 | Autoimmune hemolytic anemia (HP:0001890) | 2.16935204 |
| 72 | Keratoconjunctivitis (HP:0001096) | 2.14206270 |
| 73 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.14072297 |
| 74 | Hypochromic anemia (HP:0001931) | 2.10964185 |
| 75 | T lymphocytopenia (HP:0005403) | 2.07777450 |
| 76 | Abnormality of male internal genitalia (HP:0000022) | 2.06699861 |
| 77 | Pulmonary fibrosis (HP:0002206) | 2.01456999 |
| 78 | Stomatitis (HP:0010280) | 2.01070066 |
| 79 | Spontaneous hematomas (HP:0007420) | 2.00441570 |
| 80 | Granulocytopenia (HP:0001913) | 1.98281851 |
| 81 | Bronchiectasis (HP:0002110) | 1.95911853 |
| 82 | Squamous cell carcinoma (HP:0002860) | 1.93357759 |
| 83 | Eosinophilia (HP:0001880) | 1.92381931 |
| 84 | Stomach cancer (HP:0012126) | 1.89857667 |
| 85 | Pustule (HP:0200039) | 1.89219680 |
| 86 | Abnormality of eosinophils (HP:0001879) | 1.87226931 |
| 87 | Albinism (HP:0001022) | 1.86171070 |
| 88 | Skin ulcer (HP:0200042) | 1.85183827 |
| 89 | Arterial thrombosis (HP:0004420) | 1.84682024 |
| 90 | Severe combined immunodeficiency (HP:0004430) | 1.84214466 |
| 91 | Xerostomia (HP:0000217) | 1.83753498 |
| 92 | Gangrene (HP:0100758) | 1.81107460 |
| 93 | Hepatitis (HP:0012115) | 1.80174007 |
| 94 | Pulmonary embolism (HP:0002204) | 1.76451966 |
| 95 | Leukocytosis (HP:0001974) | 1.75152721 |
| 96 | Hypertensive crisis (HP:0100735) | 1.72957514 |
| 97 | Hypergammaglobulinemia (HP:0010702) | 1.71970057 |
| 98 | Hypoplasia of the thymus (HP:0000778) | 1.71135129 |
| 99 | Dry hair (HP:0011359) | 1.66848541 |
| 100 | Keratitis (HP:0000491) | 1.64630665 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 5.50889511 |
| 2 | RIPK4 | 5.39548745 |
| 3 | BLK | 3.44300111 |
| 4 | IRAK4 | 3.22674965 |
| 5 | SYK | 2.64754911 |
| 6 | MAP3K14 | 2.42829967 |
| 7 | PRPF4B | 2.31045810 |
| 8 | SIK2 | 2.28360188 |
| 9 | BMPR2 | 2.22124775 |
| 10 | BTK | 2.17347651 |
| 11 | IKBKE | 2.12771985 |
| 12 | SIK3 | 2.02278588 |
| 13 | TYK2 | 1.93209957 |
| 14 | CSF1R | 1.87057180 |
| 15 | ERN1 | 1.86337288 |
| 16 | IKBKB | 1.76047547 |
| 17 | TLK1 | 1.69046131 |
| 18 | LYN | 1.68085276 |
| 19 | FRK | 1.66868851 |
| 20 | MAP3K13 | 1.65913901 |
| 21 | TNK2 | 1.55278185 |
| 22 | TAOK3 | 1.54109929 |
| 23 | TBK1 | 1.53406327 |
| 24 | JAK1 | 1.51762394 |
| 25 | JAK3 | 1.49166510 |
| 26 | KIT | 1.42514228 |
| 27 | NEK9 | 1.37505156 |
| 28 | PASK | 1.37088499 |
| 29 | PRKCQ | 1.35971669 |
| 30 | CSK | 1.35465916 |
| 31 | VRK1 | 1.28420501 |
| 32 | HCK | 1.25761119 |
| 33 | MARK3 | 1.24450016 |
| 34 | MAP3K10 | 1.21159512 |
| 35 | TEC | 1.13607669 |
| 36 | ZAK | 1.12698978 |
| 37 | TXK | 1.09946112 |
| 38 | FGR | 1.03012958 |
| 39 | CHUK | 1.01484541 |
| 40 | EIF2AK3 | 0.99481945 |
| 41 | PIM1 | 0.98112716 |
| 42 | CDK19 | 0.96719864 |
| 43 | LCK | 0.95114097 |
| 44 | IRAK1 | 0.94778354 |
| 45 | JAK2 | 0.93002256 |
| 46 | ITK | 0.92940682 |
| 47 | STK10 | 0.89598239 |
| 48 | MATK | 0.87494675 |
| 49 | GRK6 | 0.84643261 |
| 50 | PDK1 | 0.79254007 |
| 51 | CCNB1 | 0.77414903 |
| 52 | FES | 0.74633790 |
| 53 | MAP4K2 | 0.72740858 |
| 54 | TAF1 | 0.71959052 |
| 55 | MAPK11 | 0.70653713 |
| 56 | MAPK12 | 0.65921613 |
| 57 | FGFR3 | 0.65613931 |
| 58 | YES1 | 0.65318340 |
| 59 | SMG1 | 0.65172305 |
| 60 | PRKCH | 0.63984528 |
| 61 | MAPK7 | 0.63329114 |
| 62 | CDK4 | 0.61159198 |
| 63 | RPS6KA5 | 0.60394135 |
| 64 | PTK2B | 0.59440619 |
| 65 | CDC42BPA | 0.59130248 |
| 66 | MELK | 0.53517230 |
| 67 | TRPM7 | 0.52094366 |
| 68 | STK11 | 0.51070091 |
| 69 | STK24 | 0.50156552 |
| 70 | MAPK13 | 0.48434945 |
| 71 | IRAK2 | 0.47010182 |
| 72 | MAP3K7 | 0.46945695 |
| 73 | PKN1 | 0.44023064 |
| 74 | HIPK2 | 0.41192616 |
| 75 | MAP3K11 | 0.41134154 |
| 76 | MST4 | 0.40730000 |
| 77 | FGFR4 | 0.40729573 |
| 78 | ABL1 | 0.40671243 |
| 79 | MAP2K3 | 0.39781235 |
| 80 | MAP3K5 | 0.36937533 |
| 81 | PRKCI | 0.36882858 |
| 82 | ZAP70 | 0.36452203 |
| 83 | SGK2 | 0.35733072 |
| 84 | FYN | 0.35473275 |
| 85 | PRKD2 | 0.35451316 |
| 86 | MAPK4 | 0.35321645 |
| 87 | OXSR1 | 0.34561595 |
| 88 | PRKCZ | 0.33050900 |
| 89 | PDPK1 | 0.32758784 |
| 90 | MAPKAPK2 | 0.32477788 |
| 91 | BCKDK | 0.30016069 |
| 92 | PRKCD | 0.28522341 |
| 93 | NUAK1 | 0.28075964 |
| 94 | PIK3CG | 0.27657913 |
| 95 | INSRR | 0.27174749 |
| 96 | DAPK3 | 0.26591734 |
| 97 | MAP3K8 | 0.25676229 |
| 98 | MAP3K1 | 0.24824643 |
| 99 | GRK1 | 0.24525466 |
| 100 | INSR | 0.23783009 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 4.68896444 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 4.62262915 |
| 3 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 4.28640536 |
| 4 | Primary immunodeficiency_Homo sapiens_hsa05340 | 4.21422427 |
| 5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.18249763 |
| 6 | Asthma_Homo sapiens_hsa05310 | 4.09808356 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.61058039 |
| 8 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 3.22721015 |
| 9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.91838442 |
| 10 | Leishmaniasis_Homo sapiens_hsa05140 | 2.78241784 |
| 11 | Viral myocarditis_Homo sapiens_hsa05416 | 2.56214178 |
| 12 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.51518854 |
| 13 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.42867539 |
| 14 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 2.35111665 |
| 15 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.97383360 |
| 16 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.80029928 |
| 17 | Influenza A_Homo sapiens_hsa05164 | 1.68128822 |
| 18 | Tuberculosis_Homo sapiens_hsa05152 | 1.62567985 |
| 19 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.57582711 |
| 20 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.53451342 |
| 21 | Osteoclast differentiation_Homo sapiens_hsa04380 | 1.51315826 |
| 22 | Measles_Homo sapiens_hsa05162 | 1.49825379 |
| 23 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 1.46060427 |
| 24 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.36632643 |
| 25 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.32122093 |
| 26 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.27701149 |
| 27 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.26842621 |
| 28 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.11946391 |
| 29 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.11524433 |
| 30 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.03164989 |
| 31 | Hepatitis B_Homo sapiens_hsa05161 | 1.01546675 |
| 32 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.00874353 |
| 33 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.97956171 |
| 34 | Alcoholism_Homo sapiens_hsa05034 | 0.91460582 |
| 35 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.90596466 |
| 36 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.87848204 |
| 37 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.82596310 |
| 38 | Phagosome_Homo sapiens_hsa04145 | 0.79821850 |
| 39 | HTLV-I infection_Homo sapiens_hsa05166 | 0.76302626 |
| 40 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.76133190 |
| 41 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.71540654 |
| 42 | Apoptosis_Homo sapiens_hsa04210 | 0.71526020 |
| 43 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.68469618 |
| 44 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.67082563 |
| 45 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.63331193 |
| 46 | Hepatitis C_Homo sapiens_hsa05160 | 0.61506536 |
| 47 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.58469712 |
| 48 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.51588170 |
| 49 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.51207133 |
| 50 | Homologous recombination_Homo sapiens_hsa03440 | 0.50006614 |
| 51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.42398558 |
| 52 | Malaria_Homo sapiens_hsa05144 | 0.37614225 |
| 53 | Legionellosis_Homo sapiens_hsa05134 | 0.37566995 |
| 54 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.34834064 |
| 55 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.34819933 |
| 56 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.34330753 |
| 57 | Platelet activation_Homo sapiens_hsa04611 | 0.33551478 |
| 58 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.32590429 |
| 59 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.32082994 |
| 60 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.30672938 |
| 61 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.29261663 |
| 62 | ABC transporters_Homo sapiens_hsa02010 | 0.27656005 |
| 63 | Shigellosis_Homo sapiens_hsa05131 | 0.27056418 |
| 64 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.26799686 |
| 65 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.23651110 |
| 66 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.22654934 |
| 67 | Prostate cancer_Homo sapiens_hsa05215 | 0.21917582 |
| 68 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.21451153 |
| 69 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.21359225 |
| 70 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.20093586 |
| 71 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.19094247 |
| 72 | Colorectal cancer_Homo sapiens_hsa05210 | 0.18822439 |
| 73 | RNA degradation_Homo sapiens_hsa03018 | 0.18347538 |
| 74 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.17427099 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.17329464 |
| 76 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.15988595 |
| 77 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.15675431 |
| 78 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.14750809 |
| 79 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.13656817 |
| 80 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.12829631 |
| 81 | Basal transcription factors_Homo sapiens_hsa03022 | 0.11304930 |
| 82 | Insulin resistance_Homo sapiens_hsa04931 | 0.10996134 |
| 83 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.10592225 |
| 84 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.10058608 |
| 85 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.09830933 |
| 86 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.09196037 |
| 87 | Base excision repair_Homo sapiens_hsa03410 | 0.07572656 |
| 88 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.07144532 |
| 89 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.06296232 |
| 90 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.05322792 |
| 91 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.04621768 |
| 92 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.04576147 |
| 93 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.03443926 |
| 94 | Olfactory transduction_Homo sapiens_hsa04740 | 0.01961075 |
| 95 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.01359264 |
| 96 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.01007768 |
| 97 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.00974486 |
| 98 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.00696030 |
| 99 | Pertussis_Homo sapiens_hsa05133 | 0.00571914 |
| 100 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | -0.0091760 |

