Rank | Gene Set | Z-score |
---|---|---|
1 | response to peptidoglycan (GO:0032494) | 6.00961915 |
2 | positive regulation by symbiont of host defense response (GO:0052509) | 5.96842301 |
3 | modulation by symbiont of host defense response (GO:0052031) | 5.96842301 |
4 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.96842301 |
5 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.96842301 |
6 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.96842301 |
7 | modulation by symbiont of host immune response (GO:0052553) | 5.96842301 |
8 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.56967498 |
9 | negative regulation of interleukin-12 production (GO:0032695) | 5.49894981 |
10 | neutrophil activation involved in immune response (GO:0002283) | 5.11589259 |
11 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.09550821 |
12 | macrophage activation involved in immune response (GO:0002281) | 5.05409432 |
13 | detection of molecule of bacterial origin (GO:0032490) | 5.02529134 |
14 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.68269885 |
15 | negative regulation of cell killing (GO:0031342) | 4.68269885 |
16 | detection of other organism (GO:0098543) | 4.52370603 |
17 | cellular extravasation (GO:0045123) | 4.44721330 |
18 | regulation of interferon-beta biosynthetic process (GO:0045357) | 4.40918402 |
19 | microglial cell activation (GO:0001774) | 4.33978585 |
20 | production of molecular mediator involved in inflammatory response (GO:0002532) | 4.33229594 |
21 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 4.20998521 |
22 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 4.15685271 |
23 | positive regulation of type 2 immune response (GO:0002830) | 4.14157414 |
24 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.13506642 |
25 | detection of external biotic stimulus (GO:0098581) | 4.12322777 |
26 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.08504286 |
27 | response to host immune response (GO:0052572) | 4.08504286 |
28 | immunoglobulin mediated immune response (GO:0016064) | 4.05244319 |
29 | detection of biotic stimulus (GO:0009595) | 3.97577192 |
30 | detection of bacterium (GO:0016045) | 3.93882726 |
31 | macrophage activation (GO:0042116) | 3.93750804 |
32 | regulation of gamma-delta T cell activation (GO:0046643) | 3.92022129 |
33 | regulation of tolerance induction (GO:0002643) | 3.91978429 |
34 | regulation of T cell tolerance induction (GO:0002664) | 3.85353268 |
35 | T-helper 1 type immune response (GO:0042088) | 3.84826456 |
36 | positive regulation of mast cell activation (GO:0033005) | 3.75799158 |
37 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.70995876 |
38 | response to host (GO:0075136) | 3.70995876 |
39 | response to host defenses (GO:0052200) | 3.70995876 |
40 | neutrophil mediated immunity (GO:0002446) | 3.69648938 |
41 | respiratory burst (GO:0045730) | 3.68560250 |
42 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 3.67723080 |
43 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.67097132 |
44 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.63619603 |
45 | positive regulation of tolerance induction (GO:0002645) | 3.63215191 |
46 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.62303973 |
47 | leukocyte aggregation (GO:0070486) | 3.57668399 |
48 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 3.57604793 |
49 | neutrophil activation (GO:0042119) | 3.54522787 |
50 | myeloid cell activation involved in immune response (GO:0002275) | 3.54250305 |
51 | negative regulation of interleukin-17 production (GO:0032700) | 3.54178236 |
52 | granulocyte activation (GO:0036230) | 3.44835373 |
53 | negative regulation of T cell mediated immunity (GO:0002710) | 3.43897618 |
54 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.42283167 |
55 | positive regulation of cellular amide metabolic process (GO:0034250) | 3.41529622 |
56 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.39545570 |
57 | regulation of mast cell activation (GO:0033003) | 3.38714343 |
58 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.38013927 |
59 | regulation of mast cell degranulation (GO:0043304) | 3.37528782 |
60 | antigen processing and presentation of endogenous antigen (GO:0019883) | 3.34448283 |
61 | defense response to protozoan (GO:0042832) | 3.33213514 |
62 | regulation of interleukin-12 production (GO:0032655) | 3.32901952 |
63 | response to muramyl dipeptide (GO:0032495) | 3.30718865 |
64 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.29672526 |
65 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 3.28454154 |
66 | myeloid leukocyte mediated immunity (GO:0002444) | 3.25067880 |
67 | positive regulation of antigen processing and presentation (GO:0002579) | 3.24536780 |
68 | positive regulation of mast cell activation involved in immune response (GO:0033008) | 3.24523761 |
69 | positive regulation of mast cell degranulation (GO:0043306) | 3.24523761 |
70 | regulation of interleukin-1 beta secretion (GO:0050706) | 3.22685256 |
71 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.21695620 |
72 | regulation of antigen processing and presentation (GO:0002577) | 3.20573676 |
73 | positive regulation of interferon-alpha production (GO:0032727) | 3.19813878 |
74 | regulation of mast cell activation involved in immune response (GO:0033006) | 3.19038209 |
75 | B cell mediated immunity (GO:0019724) | 3.17809239 |
76 | positive regulation of interleukin-1 secretion (GO:0050716) | 3.17243653 |
77 | antigen processing and presentation of endogenous peptide antigen (GO:0002483) | 3.15082749 |
78 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.14977203 |
79 | regulation of interleukin-17 production (GO:0032660) | 3.13830837 |
80 | regulation of T-helper 1 cell differentiation (GO:0045625) | 3.13740467 |
81 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.12920475 |
82 | positive regulation of interleukin-10 production (GO:0032733) | 3.12246061 |
83 | cytokine secretion (GO:0050663) | 3.11726300 |
84 | regulation of interleukin-8 biosynthetic process (GO:0045414) | 3.10653387 |
85 | regulation of interferon-alpha production (GO:0032647) | 3.10070709 |
86 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.09510107 |
87 | regulation of type 2 immune response (GO:0002828) | 3.06728565 |
88 | regulation of T-helper 2 cell differentiation (GO:0045628) | 3.06717870 |
89 | positive regulation of interleukin-17 production (GO:0032740) | 3.05592515 |
90 | regulation of myeloid leukocyte mediated immunity (GO:0002886) | 3.04213691 |
91 | regulation of vitamin D biosynthetic process (GO:0060556) | 3.01593356 |
92 | response to protozoan (GO:0001562) | 3.01365073 |
93 | positive regulation of T-helper cell differentiation (GO:0045624) | 3.01279826 |
94 | T cell migration (GO:0072678) | 2.99627396 |
95 | cellular response to type I interferon (GO:0071357) | 2.99182430 |
96 | type I interferon signaling pathway (GO:0060337) | 2.99182430 |
97 | positive regulation of interleukin-12 production (GO:0032735) | 2.95634481 |
98 | response to type I interferon (GO:0034340) | 2.95170045 |
99 | dendritic cell chemotaxis (GO:0002407) | 2.94278844 |
100 | positive regulation of myeloid leukocyte mediated immunity (GO:0002888) | 2.93710367 |
Rank | Gene Set | Z-score |
---|---|---|
1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 6.40806701 |
2 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.39605156 |
3 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 5.32591431 |
4 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 4.14690371 |
5 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.84779141 |
6 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.66295637 |
7 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 3.62539251 |
8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.58114547 |
9 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.56874128 |
10 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.46957031 |
11 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 3.44197353 |
12 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 3.40267567 |
13 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 3.13666468 |
14 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.98529246 |
15 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.83611812 |
16 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.69207336 |
17 | SPI1_23547873_ChIP-Seq_NB4_Human | 2.62479569 |
18 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.57571218 |
19 | SPI1_23127762_ChIP-Seq_K562_Human | 2.53217764 |
20 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.51710752 |
21 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 2.49224404 |
22 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.43209810 |
23 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.42966788 |
24 | VDR_24787735_ChIP-Seq_THP-1_Human | 2.31818056 |
25 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.26293768 |
26 | VDR_24763502_ChIP-Seq_THP-1_Human | 2.20797298 |
27 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 2.18524342 |
28 | MYB_26560356_Chip-Seq_TH2_Human | 2.01371484 |
29 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.96319254 |
30 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.95346584 |
31 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.88103070 |
32 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.86602989 |
33 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.84834215 |
34 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.82997901 |
35 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.82866780 |
36 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.77351697 |
37 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.76629083 |
38 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.66696461 |
39 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.64252191 |
40 | MAF_26560356_Chip-Seq_TH1_Human | 1.62383166 |
41 | GATA1_22025678_ChIP-Seq_K562_Human | 1.56448848 |
42 | MYB_26560356_Chip-Seq_TH1_Human | 1.52851378 |
43 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.51725856 |
44 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 1.49265859 |
45 | NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.49158696 |
46 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.47880262 |
47 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.42081960 |
48 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.41424579 |
49 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.37028759 |
50 | GATA3_26560356_Chip-Seq_TH2_Human | 1.36893300 |
51 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 1.35960189 |
52 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.33182716 |
53 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.30312306 |
54 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.28857903 |
55 | UTX_26944678_Chip-Seq_JUKART_Human | 1.27097535 |
56 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 1.21935023 |
57 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 1.21056060 |
58 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.20864983 |
59 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.16095744 |
60 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.14475029 |
61 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13293506 |
62 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.12215687 |
63 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.11326985 |
64 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.09973221 |
65 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.09577924 |
66 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.07792276 |
67 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.07730936 |
68 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.03998915 |
69 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.99514072 |
70 | MAF_26560356_Chip-Seq_TH2_Human | 0.95070070 |
71 | MYC_22102868_ChIP-Seq_BL_Human | 0.93313107 |
72 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.93231175 |
73 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.91894140 |
74 | GATA1_19941826_ChIP-Seq_K562_Human | 0.91493486 |
75 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 0.87901895 |
76 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.87582730 |
77 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.86635133 |
78 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.86363849 |
79 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.85473433 |
80 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85012491 |
81 | GATA2_19941826_ChIP-Seq_K562_Human | 0.83956111 |
82 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83789323 |
83 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.83726618 |
84 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.80370716 |
85 | TFEB_21752829_ChIP-Seq_HELA_Human | 0.80002284 |
86 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.79814805 |
87 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.77214049 |
88 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 0.77183804 |
89 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.74058582 |
90 | STAT1_20625510_ChIP-Seq_HELA_Human | 0.73705297 |
91 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 0.68909574 |
92 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.67040882 |
93 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.64097693 |
94 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.61307034 |
95 | KLF1_20508144_ChIP-Seq_FETAL-LIVER-ERYTHROID_Mouse | 0.61274592 |
96 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.59611051 |
97 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 0.58082190 |
98 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 0.57577145 |
99 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.57477072 |
100 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.57126801 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003724_increased_susceptibility_to | 4.60106334 |
2 | MP0003303_peritoneal_inflammation | 4.33054366 |
3 | MP0001835_abnormal_antigen_presentation | 4.09671316 |
4 | MP0003436_decreased_susceptibility_to | 3.65994771 |
5 | MP0009785_altered_susceptibility_to | 3.46319691 |
6 | MP0006082_CNS_inflammation | 3.30505308 |
7 | MP0002148_abnormal_hypersensitivity_rea | 3.27515173 |
8 | MP0002419_abnormal_innate_immunity | 3.20064726 |
9 | MP0005671_abnormal_response_to | 2.93509953 |
10 | MP0005000_abnormal_immune_tolerance | 2.93108558 |
11 | MP0005025_abnormal_response_to | 2.81742714 |
12 | MP0000685_abnormal_immune_system | 2.80151774 |
13 | MP0001790_abnormal_immune_system | 2.72110414 |
14 | MP0005387_immune_system_phenotype | 2.72110414 |
15 | MP0001800_abnormal_humoral_immune | 2.67448829 |
16 | MP0002452_abnormal_antigen_presenting | 2.57993177 |
17 | MP0002723_abnormal_immune_serum | 2.50907116 |
18 | MP0009278_abnormal_bone_marrow | 2.24435658 |
19 | MP0001819_abnormal_immune_cell | 2.21363368 |
20 | MP0002420_abnormal_adaptive_immunity | 2.20981340 |
21 | MP0009764_decreased_sensitivity_to | 2.10354346 |
22 | MP0003191_abnormal_cellular_cholesterol | 2.05393844 |
23 | MP0001533_abnormal_skeleton_physiology | 2.04868316 |
24 | MP0008260_abnormal_autophagy | 2.02697521 |
25 | MP0003172_abnormal_lysosome_physiology | 2.01080985 |
26 | MP0003300_gastrointestinal_ulcer | 1.94290841 |
27 | MP0001845_abnormal_inflammatory_respons | 1.93894957 |
28 | MP0005464_abnormal_platelet_physiology | 1.90220527 |
29 | MP0004947_skin_inflammation | 1.87832161 |
30 | MP0003075_altered_response_to | 1.86558234 |
31 | MP0002405_respiratory_system_inflammati | 1.81355473 |
32 | MP0005058_abnormal_lysosome_morphology | 1.80326004 |
33 | MP0003828_pulmonary_edema | 1.79310426 |
34 | MP0010155_abnormal_intestine_physiology | 1.74071176 |
35 | MP0001545_abnormal_hematopoietic_system | 1.70896218 |
36 | MP0005397_hematopoietic_system_phenotyp | 1.70896218 |
37 | MP0004510_myositis | 1.68985951 |
38 | MP0008469_abnormal_protein_level | 1.65058133 |
39 | MP0000343_altered_response_to | 1.65034551 |
40 | MP0005451_abnormal_body_composition | 1.59648879 |
41 | MP0000716_abnormal_immune_system | 1.59522257 |
42 | MP0002998_abnormal_bone_remodeling | 1.57890658 |
43 | MP0005310_abnormal_salivary_gland | 1.56140758 |
44 | MP0003690_abnormal_glial_cell | 1.55113343 |
45 | MP0000858_altered_metastatic_potential | 1.51105112 |
46 | MP0005166_decreased_susceptibility_to | 1.48193284 |
47 | MP0003448_altered_tumor_morphology | 1.47915068 |
48 | MP0001853_heart_inflammation | 1.47196884 |
49 | MP0002398_abnormal_bone_marrow | 1.43332962 |
50 | MP0009333_abnormal_splenocyte_physiolog | 1.38443863 |
51 | MP0004883_abnormal_blood_vessel | 1.36793088 |
52 | MP0005167_abnormal_blood-brain_barrier | 1.34802833 |
53 | MP0003656_abnormal_erythrocyte_physiolo | 1.32357888 |
54 | MP0002006_tumorigenesis | 1.30050312 |
55 | MP0008004_abnormal_stomach_pH | 1.29924027 |
56 | MP0000604_amyloidosis | 1.27740202 |
57 | MP0005164_abnormal_response_to | 1.26188922 |
58 | MP0003806_abnormal_nucleotide_metabolis | 1.23253341 |
59 | MP0002429_abnormal_blood_cell | 1.22171504 |
60 | MP0000689_abnormal_spleen_morphology | 1.21184275 |
61 | MP0002722_abnormal_immune_system | 1.17107530 |
62 | MP0000465_gastrointestinal_hemorrhage | 1.11464529 |
63 | MP0000569_abnormal_digit_pigmentation | 1.11153272 |
64 | MP0002132_abnormal_respiratory_system | 1.09639540 |
65 | MP0002166_altered_tumor_susceptibility | 1.07845122 |
66 | MP0009840_abnormal_foam_cell | 1.06479380 |
67 | MP0002277_abnormal_respiratory_mucosa | 1.06465952 |
68 | MP0009763_increased_sensitivity_to | 1.03733853 |
69 | MP0002332_abnormal_exercise_endurance | 0.98024628 |
70 | MP0003763_abnormal_thymus_physiology | 0.96105499 |
71 | MP0009765_abnormal_xenobiotic_induced | 0.93792807 |
72 | MP0003866_abnormal_defecation | 0.93767469 |
73 | MP0003183_abnormal_peptide_metabolism | 0.93094455 |
74 | MP0006054_spinal_hemorrhage | 0.91342027 |
75 | MP0001851_eye_inflammation | 0.86550593 |
76 | MP0002254_reproductive_system_inflammat | 0.78124329 |
77 | MP0000920_abnormal_myelination | 0.77028592 |
78 | MP0002138_abnormal_hepatobiliary_system | 0.76873211 |
79 | MP0005390_skeleton_phenotype | 0.76259602 |
80 | MP0008874_decreased_physiological_sensi | 0.73775648 |
81 | MP0003195_calcinosis | 0.73176866 |
82 | MP0000703_abnormal_thymus_morphology | 0.71561198 |
83 | MP0003221_abnormal_cardiomyocyte_apopto | 0.70857906 |
84 | MP0003091_abnormal_cell_migration | 0.70099993 |
85 | MP0000249_abnormal_blood_vessel | 0.68318860 |
86 | MP0003453_abnormal_keratinocyte_physiol | 0.67761662 |
87 | MP0001663_abnormal_digestive_system | 0.65257781 |
88 | MP0003795_abnormal_bone_structure | 0.64509474 |
89 | MP0004808_abnormal_hematopoietic_stem | 0.63394974 |
90 | MP0000371_diluted_coat_color | 0.62044244 |
91 | MP0004484_altered_response_of | 0.59757346 |
92 | MP0003045_fibrosis | 0.59373615 |
93 | MP0002009_preneoplasia | 0.57024255 |
94 | MP0000015_abnormal_ear_pigmentation | 0.56997414 |
95 | MP0005319_abnormal_enzyme/_coenzyme | 0.52560666 |
96 | MP0005647_abnormal_sex_gland | 0.52412763 |
97 | MP0004381_abnormal_hair_follicle | 0.50920317 |
98 | MP0010352_gastrointestinal_tract_polyps | 0.50365158 |
99 | MP0005376_homeostasis/metabolism_phenot | 0.47324518 |
100 | MP0003329_amyloid_beta_deposits | 0.47100193 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Recurrent bacterial skin infections (HP:0005406) | 6.73071453 |
2 | Eczematoid dermatitis (HP:0000976) | 6.39217117 |
3 | Recurrent abscess formation (HP:0002722) | 6.30897366 |
4 | Abnormality of macrophages (HP:0004311) | 6.23699554 |
5 | Retrobulbar optic neuritis (HP:0100654) | 5.51064190 |
6 | Optic neuritis (HP:0100653) | 5.51064190 |
7 | Orchitis (HP:0100796) | 5.40878295 |
8 | Myositis (HP:0100614) | 5.19388871 |
9 | Stomatitis (HP:0010280) | 5.15569535 |
10 | Recurrent gram-negative bacterial infections (HP:0005420) | 5.10391229 |
11 | Gastrointestinal infarctions (HP:0005244) | 4.66689825 |
12 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.53167663 |
13 | Mediastinal lymphadenopathy (HP:0100721) | 4.30028352 |
14 | Recurrent skin infections (HP:0001581) | 4.22706258 |
15 | Recurrent fungal infections (HP:0002841) | 4.10352864 |
16 | Amyloidosis (HP:0011034) | 4.08962572 |
17 | Keratoconjunctivitis sicca (HP:0001097) | 3.94167120 |
18 | Keratoconjunctivitis (HP:0001096) | 3.64395154 |
19 | Recurrent cutaneous fungal infections (HP:0011370) | 3.64319381 |
20 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.64319381 |
21 | Vasculitis (HP:0002633) | 3.61319489 |
22 | Abnormality of liposaccharide metabolism (HP:0010968) | 3.60716689 |
23 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 3.60716689 |
24 | Abnormality of glycolipid metabolism (HP:0010969) | 3.60716689 |
25 | Hemoptysis (HP:0002105) | 3.59520230 |
26 | Obstructive lung disease (HP:0006536) | 3.54795138 |
27 | Chronic obstructive pulmonary disease (HP:0006510) | 3.54795138 |
28 | Urticaria (HP:0001025) | 3.45463139 |
29 | Gingivitis (HP:0000230) | 3.34658767 |
30 | Meningitis (HP:0001287) | 3.30593933 |
31 | Leukocytosis (HP:0001974) | 3.28683413 |
32 | Increased cerebral lipofuscin (HP:0011813) | 3.23158093 |
33 | Episodic fever (HP:0001954) | 3.19209473 |
34 | Pulmonary infiltrates (HP:0002113) | 3.18453667 |
35 | Recurrent viral infections (HP:0004429) | 3.16040055 |
36 | Spontaneous hematomas (HP:0007420) | 3.14616320 |
37 | Gangrene (HP:0100758) | 3.10579402 |
38 | Arterial thrombosis (HP:0004420) | 3.10441932 |
39 | Encephalitis (HP:0002383) | 3.08443867 |
40 | Chest pain (HP:0100749) | 3.01242777 |
41 | T lymphocytopenia (HP:0005403) | 2.97527420 |
42 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.91272991 |
43 | Abnormality of T cell number (HP:0011839) | 2.90448158 |
44 | Gingival bleeding (HP:0000225) | 2.89274395 |
45 | Hematochezia (HP:0002573) | 2.86697874 |
46 | Anorexia (HP:0002039) | 2.83424984 |
47 | Amaurosis fugax (HP:0100576) | 2.82493241 |
48 | Loss of speech (HP:0002371) | 2.70683952 |
49 | Peritonitis (HP:0002586) | 2.67482803 |
50 | Vacuolated lymphocytes (HP:0001922) | 2.59148422 |
51 | Prolonged bleeding time (HP:0003010) | 2.54922604 |
52 | Increased serum ferritin (HP:0003281) | 2.53326509 |
53 | Myocardial infarction (HP:0001658) | 2.49162604 |
54 | Increased IgM level (HP:0003496) | 2.48004770 |
55 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.47540882 |
56 | Autoimmune thrombocytopenia (HP:0001973) | 2.46081178 |
57 | Vertigo (HP:0002321) | 2.45071157 |
58 | Pulmonary embolism (HP:0002204) | 2.42330900 |
59 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 2.40686595 |
60 | Cellulitis (HP:0100658) | 2.37970439 |
61 | Epistaxis (HP:0000421) | 2.37745704 |
62 | Abnormality of the endocardium (HP:0004306) | 2.37093557 |
63 | Petechiae (HP:0000967) | 2.36935249 |
64 | Dysostosis multiplex (HP:0000943) | 2.36065919 |
65 | Malnutrition (HP:0004395) | 2.35775096 |
66 | Polyneuropathy (HP:0001271) | 2.35433768 |
67 | Osteomyelitis (HP:0002754) | 2.32679966 |
68 | Increased IgE level (HP:0003212) | 2.32086445 |
69 | Systemic lupus erythematosus (HP:0002725) | 2.29169814 |
70 | Premature loss of primary teeth (HP:0006323) | 2.25425367 |
71 | Eosinophilia (HP:0001880) | 2.22965713 |
72 | Purpura (HP:0000979) | 2.22417881 |
73 | Abnormality of the pleura (HP:0002103) | 2.21912898 |
74 | Colitis (HP:0002583) | 2.20291477 |
75 | Granulocytopenia (HP:0001913) | 2.17587170 |
76 | Chronic otitis media (HP:0000389) | 2.16149429 |
77 | Inflammation of the large intestine (HP:0002037) | 2.14974220 |
78 | Disinhibition (HP:0000734) | 2.13728214 |
79 | Abnormality of T cells (HP:0002843) | 2.06977802 |
80 | Abnormality of iron homeostasis (HP:0011031) | 2.06022274 |
81 | Cheilitis (HP:0100825) | 2.02536414 |
82 | Sepsis (HP:0100806) | 2.01337813 |
83 | Pustule (HP:0200039) | 2.00303366 |
84 | Fatigue (HP:0012378) | 1.99031286 |
85 | Glomerulopathy (HP:0100820) | 1.98863516 |
86 | Gastrointestinal inflammation (HP:0004386) | 1.97352411 |
87 | Abnormality of the peritoneum (HP:0002585) | 1.93361906 |
88 | Joint swelling (HP:0001386) | 1.89900082 |
89 | Hepatosplenomegaly (HP:0001433) | 1.89010519 |
90 | Abnormality of polysaccharide metabolism (HP:0011012) | 1.88770110 |
91 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 1.88770110 |
92 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 1.88770110 |
93 | Recurrent pneumonia (HP:0006532) | 1.88382102 |
94 | Hypergammaglobulinemia (HP:0010702) | 1.88342664 |
95 | Arthralgia (HP:0002829) | 1.88232518 |
96 | Keratitis (HP:0000491) | 1.87770641 |
97 | Acne (HP:0001061) | 1.83742593 |
98 | Thrombophlebitis (HP:0004418) | 1.82532026 |
99 | Mutism (HP:0002300) | 1.81580086 |
100 | Splenomegaly (HP:0001744) | 1.81417286 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RIPK4 | 5.00195119 |
2 | TYK2 | 3.60812907 |
3 | BLK | 3.35279790 |
4 | CSK | 3.09087870 |
5 | IRAK3 | 2.99837844 |
6 | MAP3K14 | 2.89495674 |
7 | IRAK4 | 2.87809494 |
8 | FGR | 2.61883421 |
9 | MATK | 2.51457607 |
10 | JAK3 | 2.42849912 |
11 | MAP2K3 | 2.30897658 |
12 | MAP4K1 | 2.30232331 |
13 | PRPF4B | 2.22716131 |
14 | IKBKE | 2.10647256 |
15 | ZAP70 | 2.01545441 |
16 | GRK7 | 1.92714070 |
17 | JAK1 | 1.92162831 |
18 | MAP3K13 | 1.90957928 |
19 | TXK | 1.89609678 |
20 | FES | 1.78595877 |
21 | BMPR2 | 1.74916630 |
22 | MAP3K3 | 1.58207944 |
23 | TBK1 | 1.53524453 |
24 | SYK | 1.51545184 |
25 | JAK2 | 1.50902886 |
26 | IKBKB | 1.45471837 |
27 | TAOK3 | 1.44769647 |
28 | IRAK1 | 1.44516120 |
29 | KIT | 1.40867522 |
30 | LYN | 1.39103461 |
31 | IRAK2 | 1.37189196 |
32 | HCK | 1.36524278 |
33 | ERN1 | 1.31537968 |
34 | TAOK1 | 1.29422243 |
35 | EPHB1 | 1.27200637 |
36 | BTK | 1.23998878 |
37 | MAP3K6 | 1.23138001 |
38 | PIK3CG | 1.22777778 |
39 | MAP3K1 | 1.21576802 |
40 | CSF1R | 1.16854731 |
41 | TNK2 | 1.13844658 |
42 | GRK6 | 1.10618557 |
43 | KSR2 | 1.10151927 |
44 | YES1 | 1.10145592 |
45 | FGFR3 | 1.09492818 |
46 | FGFR4 | 1.09250753 |
47 | LCK | 0.95405751 |
48 | TAOK2 | 0.95247441 |
49 | MAP3K5 | 0.94688335 |
50 | TGFBR2 | 0.92710685 |
51 | CDC42BPA | 0.89276335 |
52 | SIK3 | 0.89190105 |
53 | STK10 | 0.87282316 |
54 | MAP3K11 | 0.85676068 |
55 | MARK3 | 0.82638374 |
56 | DDR2 | 0.80942788 |
57 | TEC | 0.77936625 |
58 | PDK1 | 0.74245046 |
59 | MOS | 0.73883835 |
60 | CAMKK2 | 0.72726734 |
61 | PDPK1 | 0.71431859 |
62 | DAPK2 | 0.68850509 |
63 | CHUK | 0.65842465 |
64 | MARK2 | 0.64861749 |
65 | ITK | 0.63996355 |
66 | PDK2 | 0.62090093 |
67 | EPHA3 | 0.61449611 |
68 | MAP3K2 | 0.59805465 |
69 | ADRBK2 | 0.58645560 |
70 | MAPK7 | 0.57418509 |
71 | FYN | 0.52732791 |
72 | ARAF | 0.51814487 |
73 | MAP2K4 | 0.51498345 |
74 | SGK3 | 0.49766572 |
75 | LRRK2 | 0.48979030 |
76 | KSR1 | 0.48236501 |
77 | NLK | 0.43065255 |
78 | PIM1 | 0.42454971 |
79 | ACVR1B | 0.41433567 |
80 | ABL1 | 0.38383261 |
81 | CAMK1D | 0.37344908 |
82 | RAF1 | 0.36950469 |
83 | SGK2 | 0.35801164 |
84 | PTK2B | 0.35635202 |
85 | STK24 | 0.35464922 |
86 | EGFR | 0.34853974 |
87 | PDGFRB | 0.34639087 |
88 | MAPK12 | 0.32196039 |
89 | CDK19 | 0.31034238 |
90 | PRKCQ | 0.30860736 |
91 | RPS6KC1 | 0.29748245 |
92 | RPS6KL1 | 0.29748245 |
93 | CAMK4 | 0.28937772 |
94 | PRKCD | 0.28715414 |
95 | PRKD2 | 0.26105730 |
96 | NEK9 | 0.24250521 |
97 | RPS6KA6 | 0.23999708 |
98 | TESK2 | 0.23913571 |
99 | TYRO3 | 0.23599495 |
100 | INSR | 0.22672895 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Leishmaniasis_Homo sapiens_hsa05140 | 3.34461351 |
2 | Osteoclast differentiation_Homo sapiens_hsa04380 | 3.02318445 |
3 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.86543010 |
4 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.80678363 |
5 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.64953712 |
6 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.54478537 |
7 | Tuberculosis_Homo sapiens_hsa05152 | 2.50459426 |
8 | Allograft rejection_Homo sapiens_hsa05330 | 2.47249998 |
9 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.42260980 |
10 | Legionellosis_Homo sapiens_hsa05134 | 2.40444247 |
11 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 2.29398990 |
12 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.08890903 |
13 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.05333974 |
14 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.01738010 |
15 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.00248452 |
16 | Malaria_Homo sapiens_hsa05144 | 1.97714724 |
17 | Pertussis_Homo sapiens_hsa05133 | 1.90440028 |
18 | Influenza A_Homo sapiens_hsa05164 | 1.80668524 |
19 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.79251905 |
20 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.77452201 |
21 | Asthma_Homo sapiens_hsa05310 | 1.76702220 |
22 | Measles_Homo sapiens_hsa05162 | 1.71594465 |
23 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.71227800 |
24 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.70342590 |
25 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.69073014 |
26 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.67619912 |
27 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.67434344 |
28 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.65184630 |
29 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 1.58393289 |
30 | Other glycan degradation_Homo sapiens_hsa00511 | 1.54282613 |
31 | Phagosome_Homo sapiens_hsa04145 | 1.53699883 |
32 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.48827119 |
33 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.48591219 |
34 | Lysosome_Homo sapiens_hsa04142 | 1.46104030 |
35 | Salmonella infection_Homo sapiens_hsa05132 | 1.39908668 |
36 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.38879572 |
37 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.35618934 |
38 | Viral myocarditis_Homo sapiens_hsa05416 | 1.33721390 |
39 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.31667059 |
40 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.25418376 |
41 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.20817799 |
42 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.16558938 |
43 | Hepatitis B_Homo sapiens_hsa05161 | 1.13142937 |
44 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.12984541 |
45 | Hepatitis C_Homo sapiens_hsa05160 | 1.09688950 |
46 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.09063499 |
47 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.05991622 |
48 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 1.04948462 |
49 | Shigellosis_Homo sapiens_hsa05131 | 1.00581748 |
50 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.90875636 |
51 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.88320295 |
52 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.88175579 |
53 | Apoptosis_Homo sapiens_hsa04210 | 0.85160473 |
54 | Amoebiasis_Homo sapiens_hsa05146 | 0.84432651 |
55 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.82433091 |
56 | Platelet activation_Homo sapiens_hsa04611 | 0.75803168 |
57 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.72645472 |
58 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.70635525 |
59 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.69914557 |
60 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.69209780 |
61 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.68207188 |
62 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.67333137 |
63 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.67041218 |
64 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.60922184 |
65 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.59210990 |
66 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.58642551 |
67 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.58460383 |
68 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.57886769 |
69 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.54756840 |
70 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.53608602 |
71 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.52518959 |
72 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.50342005 |
73 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.49457604 |
74 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.47510622 |
75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.47256277 |
76 | Bladder cancer_Homo sapiens_hsa05219 | 0.45777286 |
77 | Mineral absorption_Homo sapiens_hsa04978 | 0.45506442 |
78 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.44865850 |
79 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.43863308 |
80 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.43801107 |
81 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.42259762 |
82 | Endocytosis_Homo sapiens_hsa04144 | 0.39897970 |
83 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.38353529 |
84 | Prion diseases_Homo sapiens_hsa05020 | 0.37872058 |
85 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.37799830 |
86 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.36843795 |
87 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.36759840 |
88 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.34906333 |
89 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.34185674 |
90 | Galactose metabolism_Homo sapiens_hsa00052 | 0.32347468 |
91 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.30493717 |
92 | HTLV-I infection_Homo sapiens_hsa05166 | 0.27030167 |
93 | Insulin resistance_Homo sapiens_hsa04931 | 0.26723052 |
94 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.25587648 |
95 | Endometrial cancer_Homo sapiens_hsa05213 | 0.24642214 |
96 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.23618760 |
97 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.21242597 |
98 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.19863985 |
99 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.19338239 |
100 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.18232374 |