CLIP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)5.82258017
2sarcomere organization (GO:0045214)5.18996236
3regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)5.18136095
4plasma membrane repair (GO:0001778)5.14101324
5regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO5.06227335
6sarcoplasmic reticulum calcium ion transport (GO:0070296)5.00149745
7cardiac myofibril assembly (GO:0055003)4.94440627
8regulation of skeletal muscle contraction (GO:0014819)4.80782066
9myofibril assembly (GO:0030239)4.80382835
10negative regulation of potassium ion transmembrane transporter activity (GO:1901017)4.77016024
11muscle filament sliding (GO:0030049)4.72279253
12actin-myosin filament sliding (GO:0033275)4.72279253
13regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)4.69268433
14regulation of cell communication by electrical coupling (GO:0010649)4.44539596
15regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.41322687
16negative regulation of potassium ion transmembrane transport (GO:1901380)4.17295670
17cardiac muscle contraction (GO:0060048)4.14202770
18actin-mediated cell contraction (GO:0070252)4.07022309
19cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.02421384
20regulation of relaxation of muscle (GO:1901077)3.83343822
21cell communication involved in cardiac conduction (GO:0086065)3.77998544
22positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.77910570
23macroautophagy (GO:0016236)3.76703085
24striated muscle contraction (GO:0006941)3.75657923
25membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.75390385
26ventricular cardiac muscle cell action potential (GO:0086005)3.72564057
27actomyosin structure organization (GO:0031032)3.69399277
28regulation of actin filament-based movement (GO:1903115)3.58215930
29cardiac muscle hypertrophy (GO:0003300)3.57019394
30relaxation of cardiac muscle (GO:0055119)3.51200929
31skeletal muscle adaptation (GO:0043501)3.50541712
32cell communication by electrical coupling (GO:0010644)3.50290762
33desmosome organization (GO:0002934)3.49428718
34keratinization (GO:0031424)3.49150806
35striated muscle hypertrophy (GO:0014897)3.48211884
36actin filament-based movement (GO:0030048)3.44054185
37detection of calcium ion (GO:0005513)3.41894188
38regulation of membrane repolarization (GO:0060306)3.41052144
39carnitine shuttle (GO:0006853)3.40957427
40interkinetic nuclear migration (GO:0022027)3.38801852
41regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)3.37439771
42positive regulation of cation channel activity (GO:2001259)3.34972870
43bundle of His cell to Purkinje myocyte communication (GO:0086069)3.32213984
44regulation of striated muscle contraction (GO:0006942)3.31446612
45regulation of calcium ion transmembrane transport (GO:1903169)3.27148876
46regulation of calcium ion transmembrane transporter activity (GO:1901019)3.27148876
47skeletal muscle contraction (GO:0003009)3.26829271
48cardiac conduction (GO:0061337)3.22466361
49cardiac muscle cell development (GO:0055013)3.22404923
50response to stimulus involved in regulation of muscle adaptation (GO:0014874)3.21203243
51establishment of skin barrier (GO:0061436)3.19331300
52negative regulation of protein localization to cell surface (GO:2000009)3.17456712
53cardiac cell development (GO:0055006)3.06112903
54cardiac muscle cell action potential (GO:0086001)3.03975953
55muscle hypertrophy (GO:0014896)3.03816145
56hemidesmosome assembly (GO:0031581)3.02613212
57regulation of sarcomere organization (GO:0060297)3.00029290
58cardiac muscle cell action potential involved in contraction (GO:0086002)2.94900542
59regulation of heart rate by cardiac conduction (GO:0086091)2.94698432
60protein targeting to Golgi (GO:0000042)2.91895459
61striated muscle adaptation (GO:0014888)2.90859858
62retrograde transport, vesicle recycling within Golgi (GO:0000301)2.89035050
63fatty acid transmembrane transport (GO:1902001)2.86402707
64regulation of water loss via skin (GO:0033561)2.84501788
65striated muscle atrophy (GO:0014891)2.83092255
66adult heart development (GO:0007512)2.82863612
67regulation of cardiac muscle contraction (GO:0055117)2.82529377
68muscle contraction (GO:0006936)2.82129744
69membrane depolarization during action potential (GO:0086010)2.80532491
70regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.77207374
71establishment of protein localization to Golgi (GO:0072600)2.76605800
72cardiac muscle adaptation (GO:0014887)2.73621574
73cardiac muscle hypertrophy in response to stress (GO:0014898)2.73621574
74muscle hypertrophy in response to stress (GO:0003299)2.73621574
75regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)2.71640484
76regulation of cation channel activity (GO:2001257)2.70727433
77carnitine transmembrane transport (GO:1902603)2.69726724
78regulation of the force of heart contraction (GO:0002026)2.68643488
79positive regulation of ion transmembrane transporter activity (GO:0032414)2.66417736
80cardiac muscle tissue morphogenesis (GO:0055008)2.65633957
81muscle system process (GO:0003012)2.65452896
82potassium ion import (GO:0010107)2.65430993
83relaxation of muscle (GO:0090075)2.63004905
84activation of protein kinase A activity (GO:0034199)2.61286997
85regulation of acyl-CoA biosynthetic process (GO:0050812)2.59713672
86positive regulation of potassium ion transmembrane transporter activity (GO:1901018)2.58536874
87regulation of calcineurin-NFAT signaling cascade (GO:0070884)2.57189615
88regulation of heart rate (GO:0002027)2.56735419
89response to inactivity (GO:0014854)2.56159268
90negative regulation of potassium ion transport (GO:0043267)2.55956405
91positive regulation of potassium ion transmembrane transport (GO:1901381)2.55367753
92tricarboxylic acid cycle (GO:0006099)2.54246130
93regulation of cardiac muscle cell contraction (GO:0086004)2.52072265
94import into cell (GO:0098657)2.51958320
95regulation of hippo signaling (GO:0035330)2.51455056
96oxygen transport (GO:0015671)2.49749789
97negative regulation of cytosolic calcium ion concentration (GO:0051481)2.48502298
98regulation of heart contraction (GO:0008016)2.48438371
99muscle tissue morphogenesis (GO:0060415)2.47919264
100muscle fiber development (GO:0048747)2.46740818
101myoblast fusion (GO:0007520)2.46620587
102regulation of p38MAPK cascade (GO:1900744)2.44634629
103insulin-like growth factor receptor signaling pathway (GO:0048009)2.43860609
104nucleus localization (GO:0051647)2.42203277
105amino-acid betaine transport (GO:0015838)2.41968451
106carnitine transport (GO:0015879)2.41968451
107regulation of protein polyubiquitination (GO:1902914)2.41263534
108muscle atrophy (GO:0014889)2.39430134
109heart trabecula formation (GO:0060347)2.36173164
110positive regulation of fatty acid oxidation (GO:0046321)2.36052014
111positive regulation of heart contraction (GO:0045823)2.35990079
112muscle adaptation (GO:0043500)2.33751779
113regulation of synapse structural plasticity (GO:0051823)2.33596911
114response to muscle activity (GO:0014850)2.32594519
115growth hormone receptor signaling pathway (GO:0060396)2.32472265
116syncytium formation by plasma membrane fusion (GO:0000768)2.28558662
117vesicle transport along microtubule (GO:0047496)2.27322963
118pericardium development (GO:0060039)2.26963028
119smooth muscle tissue development (GO:0048745)2.25435363
120keratinocyte proliferation (GO:0043616)2.24571148
121iron ion import (GO:0097286)2.21866584
122positive regulation of fatty acid beta-oxidation (GO:0032000)2.20512524
123regulation of energy homeostasis (GO:2000505)2.19689808
124negative regulation of Rho protein signal transduction (GO:0035024)2.15993283
125keratinocyte differentiation (GO:0030216)2.14342051
126peptide cross-linking (GO:0018149)2.13972622
127skeletal muscle fiber development (GO:0048741)2.13300147
128myotube cell development (GO:0014904)2.10909806
129skeletal muscle tissue development (GO:0007519)2.10148094
130regulation of sequestering of triglyceride (GO:0010889)2.09769513
131regulation of protein localization to cell surface (GO:2000008)2.08583595
132regulation of muscle adaptation (GO:0043502)2.06020290
133cytoplasmic mRNA processing body assembly (GO:0033962)2.05627743
134syncytium formation (GO:0006949)2.02419473
135lipid translocation (GO:0034204)2.01546454
136phospholipid translocation (GO:0045332)2.01546454
137cell-substrate junction assembly (GO:0007044)2.01540219
138cellular response to growth hormone stimulus (GO:0071378)2.01312727
139skin morphogenesis (GO:0043589)2.00801744
140early endosome to late endosome transport (GO:0045022)2.00379715
141negative regulation of systemic arterial blood pressure (GO:0003085)1.99947475
142multicellular organismal water homeostasis (GO:0050891)1.99414898
143skeletal muscle tissue regeneration (GO:0043403)1.99041033
144regulation of branching involved in salivary gland morphogenesis (GO:0060693)1.98270548
145interleukin-6-mediated signaling pathway (GO:0070102)1.98257850
146metanephric mesenchyme development (GO:0072075)1.97282876
147positive regulation of p38MAPK cascade (GO:1900745)1.96836247
148regulation of cardiac muscle hypertrophy (GO:0010611)1.96025003
149protein localization to Golgi apparatus (GO:0034067)1.95877013
150myotube differentiation (GO:0014902)1.95826062
151regulation of sodium ion transmembrane transport (GO:1902305)1.94779792
152water homeostasis (GO:0030104)1.94616835
153regulation of axon extension involved in axon guidance (GO:0048841)1.93656224
154chemical homeostasis within a tissue (GO:0048875)1.92893814
155positive regulation of sodium ion transmembrane transport (GO:1902307)1.92679480

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human3.39565642
2EP300_21415370_ChIP-Seq_HL-1_Mouse2.26782624
3DROSHA_22980978_ChIP-Seq_HELA_Human2.11725013
4CDX2_19796622_ChIP-Seq_MESCs_Mouse2.07055177
5GBX2_23144817_ChIP-Seq_PC3_Human2.01221080
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.82873035
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.71668216
8ESR1_21235772_ChIP-Seq_MCF-7_Human1.71349844
9ZNF217_24962896_ChIP-Seq_MCF-7_Human1.66454202
10ESR1_20079471_ChIP-ChIP_T-47D_Human1.61975633
11* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.61673790
12STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.60406356
13RNF2_18974828_ChIP-Seq_MESCs_Mouse1.59012266
14EZH2_18974828_ChIP-Seq_MESCs_Mouse1.59012266
15SMAD_19615063_ChIP-ChIP_OVARY_Human1.57356167
16TBX20_22328084_ChIP-Seq_HEART_Mouse1.56571335
17TBX20_22080862_ChIP-Seq_HEART_Mouse1.56571335
18SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.56071076
19JARID2_20064375_ChIP-Seq_MESCs_Mouse1.52305673
20* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.51408384
21SMAD4_21799915_ChIP-Seq_A2780_Human1.49597979
22SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.48473679
23CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.47672423
24TP53_16413492_ChIP-PET_HCT116_Human1.47007722
25ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.44942806
26ZNF274_21170338_ChIP-Seq_K562_Hela1.43194956
27AHR_22903824_ChIP-Seq_MCF-7_Human1.42752756
28TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.41443117
29AR_21572438_ChIP-Seq_LNCaP_Human1.38402102
30ARNT_22903824_ChIP-Seq_MCF-7_Human1.37238464
31PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.36985672
32EZH2_27294783_Chip-Seq_ESCs_Mouse1.35662865
33* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.34374017
34EZH2_27304074_Chip-Seq_ESCs_Mouse1.34372198
35SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.33057108
36* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.31750531
37JARID2_20075857_ChIP-Seq_MESCs_Mouse1.30304997
38TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.27866716
39* RNF2_27304074_Chip-Seq_ESCs_Mouse1.25978459
40TP63_23658742_ChIP-Seq_EP156T_Human1.25298900
41GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.25198766
42* SUZ12_27294783_Chip-Seq_ESCs_Mouse1.24955436
43NR3C1_23031785_ChIP-Seq_PC12_Mouse1.22985812
44TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.22312578
45PIAS1_25552417_ChIP-Seq_VCAP_Human1.21314642
46* FOXM1_26456572_ChIP-Seq_MCF-7_Human1.21021309
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.20493095
48GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.20254678
49BCAT_22108803_ChIP-Seq_LS180_Human1.19721977
50SOX2_21211035_ChIP-Seq_LN229_Gbm1.18996503
51BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.17760045
52CTNNB1_20460455_ChIP-Seq_HCT116_Human1.17638987
53JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16821381
54* RARB_27405468_Chip-Seq_BRAIN_Mouse1.16344610
55GATA2_21666600_ChIP-Seq_HMVEC_Human1.15713617
56* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.14283548
57* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.14154265
58STAT6_21828071_ChIP-Seq_BEAS2B_Human1.14069565
59AR_25329375_ChIP-Seq_VCAP_Human1.13917551
60SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.13893339
61TCF4_18268006_ChIP-ChIP_LS174T_Human1.13872782
62AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.13732455
63ER_23166858_ChIP-Seq_MCF-7_Human1.12671991
64* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.10665984
65* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.10665984
66FOXO3_23340844_ChIP-Seq_DLD1_Human1.09642993
67EED_16625203_ChIP-ChIP_MESCs_Mouse1.09001906
68SOX9_24532713_ChIP-Seq_HFSC_Mouse1.08780170
69AR_19668381_ChIP-Seq_PC3_Human1.07070536
70BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.06445536
71TP53_18474530_ChIP-ChIP_U2OS_Human1.06345092
72* CJUN_26792858_Chip-Seq_BT549_Human1.06271046
73TRIM28_21343339_ChIP-Seq_HEK293_Human1.04669050
74SMAD3_21741376_ChIP-Seq_HESCs_Human1.04458002
75Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.04118717
76STAT3_23295773_ChIP-Seq_U87_Human1.03940464
77POU3F2_20337985_ChIP-ChIP_501MEL_Human1.03384848
78TCF4_23295773_ChIP-Seq_U87_Human1.02436217
79RXR_22108803_ChIP-Seq_LS180_Human1.02362361
80* EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.02202460
81ESR2_21235772_ChIP-Seq_MCF-7_Human1.01376494
82CTBP2_25329375_ChIP-Seq_LNCAP_Human1.00496706
83* FOXA2_19822575_ChIP-Seq_HepG2_Human0.99711204
84TOP2B_26459242_ChIP-Seq_MCF-7_Human0.99438987
85SMAD4_21741376_ChIP-Seq_HESCs_Human0.99405617
86NR3C1_21868756_ChIP-Seq_MCF10A_Human0.99159403
87NFIB_24661679_ChIP-Seq_LUNG_Mouse0.98885749
88SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.98303814
89BRD4_25478319_ChIP-Seq_HGPS_Human0.97717288
90VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.97508816
91SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.97437327
92TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.97197854
93FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.96398719
94* PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.96265368
95MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.95511595
96TAF15_26573619_Chip-Seq_HEK293_Human0.95353125
97SMAD3_21741376_ChIP-Seq_EPCs_Human0.95213391
98* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.94584870
99* ZFP57_27257070_Chip-Seq_ESCs_Mouse0.94347511
100ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.94206227
101YAP1_20516196_ChIP-Seq_MESCs_Mouse0.93835426
102REST_21632747_ChIP-Seq_MESCs_Mouse0.93761990
103CTBP1_25329375_ChIP-Seq_LNCAP_Human0.92781394
104SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.92717835
105* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.92539434
106TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.92438093
107MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.92196565
108P63_26484246_Chip-Seq_KERATINOCYTES_Human0.91977182
109NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.91956251
110NRF2_20460467_ChIP-Seq_MEFs_Mouse0.91956251
111EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.91191443
112* EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.90686704
113* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.90534356
114RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89672247
115VDR_24787735_ChIP-Seq_THP-1_Human0.89581077
116JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.89565373
117* AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.89534454
118* ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.89418069
119NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.89332328
120VDR_22108803_ChIP-Seq_LS180_Human0.88941030
121TP63_17297297_ChIP-ChIP_HaCaT_Human0.87395348
122KDM2B_26808549_Chip-Seq_K562_Human0.87159648
123P300_19829295_ChIP-Seq_ESCs_Human0.86375259
124IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.85358553
125CBP_20019798_ChIP-Seq_JUKART_Human0.85358553
126ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.85148187
127WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse0.84966268
128UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.84550502
129THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.83827858

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis5.43462749
2MP0000751_myopathy4.87341079
3MP0003646_muscle_fatigue4.62672474
4MP0004145_abnormal_muscle_electrophysio3.79286352
5MP0004084_abnormal_cardiac_muscle3.73773857
6MP0000749_muscle_degeneration3.69578648
7MP0004215_abnormal_myocardial_fiber3.52309591
8MP0004036_abnormal_muscle_relaxation3.31319191
9MP0004087_abnormal_muscle_fiber2.80721749
10MP0004130_abnormal_muscle_cell2.79186158
11MP0004510_myositis2.68995760
12MP0005330_cardiomyopathy2.60410615
13MP0005620_abnormal_muscle_contractility2.51112559
14MP0002106_abnormal_muscle_physiology2.48881409
15MP0000383_abnormal_hair_follicle2.44156467
16MP0004484_altered_response_of2.37225155
17MP0004859_abnormal_synaptic_plasticity2.30631674
18MP0002972_abnormal_cardiac_muscle2.27501751
19MP0000750_abnormal_muscle_regeneration2.12242646
20MP0005369_muscle_phenotype2.06996620
21MP0000759_abnormal_skeletal_muscle2.04356805
22MP0003137_abnormal_impulse_conducting2.02704492
23MP0002269_muscular_atrophy1.98660642
24MP0010630_abnormal_cardiac_muscle1.94491688
25MP0000747_muscle_weakness1.93695793
26MP0010678_abnormal_skin_adnexa1.87915887
27MP0008775_abnormal_heart_ventricle1.85850599
28MP0004233_abnormal_muscle_weight1.84845332
29MP0003828_pulmonary_edema1.79981946
30MP0003045_fibrosis1.77279561
31MP0005385_cardiovascular_system_phenoty1.76453701
32MP0001544_abnormal_cardiovascular_syste1.76453701
33MP0004085_abnormal_heartbeat1.76156975
34MP0004043_abnormal_pH_regulation1.71968189
35MP0009780_abnormal_chondrocyte_physiolo1.70652385
36MP0005503_abnormal_tendon_morphology1.67436869
37MP0005275_abnormal_skin_tensile1.66323857
38MP0001958_emphysema1.62395318
39MP0006138_congestive_heart_failure1.57580964
40MP0005670_abnormal_white_adipose1.55842141
41MP0002876_abnormal_thyroid_physiology1.53768689
42MP0000427_abnormal_hair_cycle1.49929498
43MP0005409_darkened_coat_color1.47532083
44MP0005666_abnormal_adipose_tissue1.46615676
45MP0002234_abnormal_pharynx_morphology1.42478673
46MP0000013_abnormal_adipose_tissue1.41577383
47MP0002909_abnormal_adrenal_gland1.36083766
48MP0004185_abnormal_adipocyte_glucose1.34245905
49MP0008961_abnormal_basal_metabolism1.32004828
50MP0003635_abnormal_synaptic_transmissio1.26204854
51MP0009046_muscle_twitch1.21201355
52MP0000569_abnormal_digit_pigmentation1.20615392
53MP0005023_abnormal_wound_healing1.20210590
54MP0005375_adipose_tissue_phenotype1.19363330
55MP0002108_abnormal_muscle_morphology1.19043997
56MP0003453_abnormal_keratinocyte_physiol1.15493090
57MP0005623_abnormal_meninges_morphology1.09080001
58MP0002332_abnormal_exercise_endurance1.08159985
59MP0000733_abnormal_muscle_development1.05785934
60MP0008569_lethality_at_weaning1.04383308
61MP0002877_abnormal_melanocyte_morpholog1.02541942
62MP0003705_abnormal_hypodermis_morpholog1.02371993
63MP0004885_abnormal_endolymph1.00784778
64MP0002060_abnormal_skin_morphology0.98549419
65MP0005595_abnormal_vascular_smooth0.98024202
66MP0003950_abnormal_plasma_membrane0.97669942
67MP0003566_abnormal_cell_adhesion0.97618636
68MP0010368_abnormal_lymphatic_system0.96587730
69MP0002168_other_aberrant_phenotype0.95945458
70MP0003221_abnormal_cardiomyocyte_apopto0.95813122
71MP0004134_abnormal_chest_morphology0.94940571
72MP0000003_abnormal_adipose_tissue0.94327510
73MP0005451_abnormal_body_composition0.91527490
74MP0001299_abnormal_eye_distance/0.88486135
75MP0010234_abnormal_vibrissa_follicle0.88455758
76MP0002063_abnormal_learning/memory/cond0.87729245
77MP0004270_analgesia0.87340684
78MP0003300_gastrointestinal_ulcer0.86233851
79MP0000266_abnormal_heart_morphology0.85558651
80MP0009745_abnormal_behavioral_response0.84836767
81MP0002971_abnormal_brown_adipose0.84392906
82MP0000467_abnormal_esophagus_morphology0.83379424
83MP0003787_abnormal_imprinting0.83171390
84MP0002796_impaired_skin_barrier0.81582018
85MP0005174_abnormal_tail_pigmentation0.81211305
86MP0002998_abnormal_bone_remodeling0.79741448
87MP0009384_cardiac_valve_regurgitation0.79516593
88MP0003279_aneurysm0.78625862
89MP0001879_abnormal_lymphatic_vessel0.78093834
90MP0005266_abnormal_metabolism0.77394911
91MP0001216_abnormal_epidermal_layer0.76332401
92MP0002098_abnormal_vibrissa_morphology0.75010399
93MP0002127_abnormal_cardiovascular_syste0.74930200
94MP0002009_preneoplasia0.74425612
95MP0010771_integument_phenotype0.73846502
96MP0000579_abnormal_nail_morphology0.73396463
97MP0010386_abnormal_urinary_bladder0.73368447
98MP0009115_abnormal_fat_cell0.72677672
99MP0003195_calcinosis0.72433941
100MP0003941_abnormal_skin_development0.72056072
101MP0000230_abnormal_systemic_arterial0.70687291
102MP0005501_abnormal_skin_physiology0.69813738
103MP0005187_abnormal_penis_morphology0.69016964
104MP0005165_increased_susceptibility_to0.68855977
105MP0001348_abnormal_lacrimal_gland0.68634685
106MP0000762_abnormal_tongue_morphology0.67973890
107MP0001440_abnormal_grooming_behavior0.67398273
108MP0002822_catalepsy0.66847538
109MP0002064_seizures0.66377140
110MP0001502_abnormal_circadian_rhythm0.66368770
111MP0004947_skin_inflammation0.66140168
112MP0001542_abnormal_bone_strength0.65542987
113MP0005164_abnormal_response_to0.64371216
114MP0005076_abnormal_cell_differentiation0.62320719
115MP0002166_altered_tumor_susceptibility0.60662648
116MP0001501_abnormal_sleep_pattern0.58145101
117MP0002128_abnormal_blood_circulation0.57910875
118MP0003091_abnormal_cell_migration0.57375877
119MP0002572_abnormal_emotion/affect_behav0.56560512
120MP0000343_altered_response_to0.56283676
121MP0000767_abnormal_smooth_muscle0.55834798
122MP0002735_abnormal_chemical_nociception0.55690534
123MP0001765_abnormal_ion_homeostasis0.55357693
124MP0002067_abnormal_sensory_capabilities0.52979895
125MP0008438_abnormal_cutaneous_collagen0.52807448
126MP0004924_abnormal_behavior0.52315044
127MP0005386_behavior/neurological_phenoty0.52315044
128MP0003879_abnormal_hair_cell0.50998977
129MP0003633_abnormal_nervous_system0.49411430
130MP0002896_abnormal_bone_mineralization0.49384032
131MP0002078_abnormal_glucose_homeostasis0.48782730
132MP0008004_abnormal_stomach_pH0.48304200
133MP0005535_abnormal_body_temperature0.47248022
134MP0001486_abnormal_startle_reflex0.46915964
135MP0005334_abnormal_fat_pad0.45810963
136MP0004272_abnormal_basement_membrane0.44983568

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)6.35762704
2Exercise-induced myalgia (HP:0003738)6.15264759
3Calf muscle hypertrophy (HP:0008981)5.55617264
4Muscle hypertrophy of the lower extremities (HP:0008968)5.47090100
5Exercise-induced muscle cramps (HP:0003710)5.15669379
6Hyporeflexia of lower limbs (HP:0002600)5.06160902
7Ventricular tachycardia (HP:0004756)4.90956489
8Muscle fiber splitting (HP:0003555)4.84912219
9Abnormality of the calf musculature (HP:0001430)4.79766932
10Right ventricular cardiomyopathy (HP:0011663)4.79457456
11Atrial fibrillation (HP:0005110)4.62893876
12Difficulty running (HP:0009046)4.43295371
13Primary atrial arrhythmia (HP:0001692)4.38534450
14Muscle fiber inclusion bodies (HP:0100299)4.20401206
15Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)4.11419064
16Subaortic stenosis (HP:0001682)4.10389293
17Abnormality of the left ventricular outflow tract (HP:0011103)4.10389293
18Supraventricular tachycardia (HP:0004755)4.10100268
19Increased connective tissue (HP:0009025)4.09687894
20Bundle branch block (HP:0011710)4.07565449
21Supraventricular arrhythmia (HP:0005115)4.02141566
22Type 1 muscle fiber predominance (HP:0003803)3.98747323
23Syncope (HP:0001279)3.93637676
24EMG: myopathic abnormalities (HP:0003458)3.89197126
25Myoglobinuria (HP:0002913)3.59245425
26Prolonged QT interval (HP:0001657)3.57090690
27Lipoatrophy (HP:0100578)3.53105485
28Myotonia (HP:0002486)3.44805291
29Asymmetric septal hypertrophy (HP:0001670)3.41922680
30Nemaline bodies (HP:0003798)3.35912641
31Ventricular fibrillation (HP:0001663)3.25531823
32Ventricular arrhythmia (HP:0004308)3.21461839
33Difficulty climbing stairs (HP:0003551)3.14882039
34Dysmetric saccades (HP:0000641)2.99030827
35Increased variability in muscle fiber diameter (HP:0003557)2.93990970
36Lip pit (HP:0100267)2.90772955
37Distal lower limb amyotrophy (HP:0008944)2.90459461
38Heart block (HP:0012722)2.86610628
39Dilated cardiomyopathy (HP:0001644)2.84282674
40Abnormality of skeletal muscle fiber size (HP:0012084)2.82029797
41Abnormal atrioventricular conduction (HP:0005150)2.80788764
42Abnormal EKG (HP:0003115)2.77857180
43Lower limb amyotrophy (HP:0007210)2.64442807
44Facial diplegia (HP:0001349)2.61465960
45Distal lower limb muscle weakness (HP:0009053)2.57341558
46Fair hair (HP:0002286)2.56814731
47Frequent falls (HP:0002359)2.50386149
48Muscle stiffness (HP:0003552)2.49665480
49Hyperkalemia (HP:0002153)2.48764090
50Atrioventricular block (HP:0001678)2.45391140
51Neck muscle weakness (HP:0000467)2.43280581
52Mildly elevated creatine phosphokinase (HP:0008180)2.41662362
53Hypoplastic ischia (HP:0003175)2.39884544
54Abnormality of secondary sexual hair (HP:0009888)2.38577587
55Abnormality of the axillary hair (HP:0100134)2.38577587
56Distal arthrogryposis (HP:0005684)2.38510253
57Round ear (HP:0100830)2.37105780
58Left ventricular hypertrophy (HP:0001712)2.31460641
59Proximal amyotrophy (HP:0007126)2.30712531
60Rhabdomyolysis (HP:0003201)2.29732478
61Scapular winging (HP:0003691)2.28192635
62Abnormality of nail color (HP:0100643)2.27521472
63Generalized hypopigmentation of hair (HP:0011358)2.26474918
64Myopathic facies (HP:0002058)2.25402749
65Palpitations (HP:0001962)2.25265269
66Alopecia of scalp (HP:0002293)2.23465609
67Areflexia of lower limbs (HP:0002522)2.20228326
68Muscular dystrophy (HP:0003560)2.19311298
69Hyperventilation (HP:0002883)2.19121428
70EMG: neuropathic changes (HP:0003445)2.17934746
71Insulin-resistant diabetes mellitus (HP:0000831)2.16918736
72Limited hip movement (HP:0008800)2.16764664
73Limb-girdle muscle atrophy (HP:0003797)2.08920553
74Focal motor seizures (HP:0011153)2.08586489
75Abnormality of the ischium (HP:0003174)2.07306612
76Fatigable weakness (HP:0003473)2.02507338
77Abnormality of the neuromuscular junction (HP:0003398)2.02507338
78Thick nail (HP:0001805)1.99381790
79Rimmed vacuoles (HP:0003805)1.98861210
80Gowers sign (HP:0003391)1.98135698
81Genetic anticipation (HP:0003743)1.97711527
82Broad metatarsal (HP:0001783)1.97383694
83Arterial tortuosity (HP:0005116)1.96624075
84Ulnar deviation of the wrist (HP:0003049)1.94456793
85Cerebral aneurysm (HP:0004944)1.94204851
86Sudden cardiac death (HP:0001645)1.91771424
87Widely spaced teeth (HP:0000687)1.91657807
88Palmoplantar hyperkeratosis (HP:0000972)1.91475663
89Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.90928821
90Vascular tortuosity (HP:0004948)1.90230108
91Cardiovascular calcification (HP:0011915)1.86625524
92Oligodontia (HP:0000677)1.85795539
93Focal seizures (HP:0007359)1.85076958
94Hypoplasia of the iris (HP:0007676)1.84263873
95Aortic dissection (HP:0002647)1.83869979
96Plantar hyperkeratosis (HP:0007556)1.81674959
97Blue irides (HP:0000635)1.80288981
98Clumsiness (HP:0002312)1.80070866
99Overgrowth (HP:0001548)1.79231647
100Palmoplantar keratoderma (HP:0000982)1.78481483
101Abnormality of the labia majora (HP:0012881)1.77522065
102Hypoplastic labia majora (HP:0000059)1.77517166
103Generalized muscle weakness (HP:0003324)1.76717319
104Bradycardia (HP:0001662)1.73926960
105Absent phalangeal crease (HP:0006109)1.73662745
106Palmar hyperkeratosis (HP:0010765)1.73368457
107Gaze-evoked nystagmus (HP:0000640)1.73113532
108Spinal rigidity (HP:0003306)1.72768096
109Hamartoma of the eye (HP:0010568)1.71555019
110Milia (HP:0001056)1.71469733
111Protruding tongue (HP:0010808)1.70973765
112Corneal erosion (HP:0200020)1.70396899
113Hip contracture (HP:0003273)1.69267947
114Follicular hyperkeratosis (HP:0007502)1.68548021
115Febrile seizures (HP:0002373)1.68375558
116Hyperglycemia (HP:0003074)1.66959766
117Abnormality of potassium homeostasis (HP:0011042)1.66200585
118Atrophic scars (HP:0001075)1.65212919
119Progressive cerebellar ataxia (HP:0002073)1.65094701
120Broad-based gait (HP:0002136)1.64959930
121Centrally nucleated skeletal muscle fibers (HP:0003687)1.63822447
122Tibial bowing (HP:0002982)1.63463748
123Limb-girdle muscle weakness (HP:0003325)1.63317534
124Visual hallucinations (HP:0002367)1.62960461
125Vascular calcification (HP:0004934)1.62102753
126Rapidly progressive (HP:0003678)1.62039017
127Congestive heart failure (HP:0001635)1.61873610
128Testicular atrophy (HP:0000029)1.61059519
129Atonic seizures (HP:0010819)1.60495949
130Truncal obesity (HP:0001956)1.60210876
131Abnormality of the nasal septum (HP:0000419)1.59969514
132Central scotoma (HP:0000603)1.59165551
133Aneurysm (HP:0002617)1.58751722
134Malignant hyperthermia (HP:0002047)1.58371773
135Hypotrichosis (HP:0001006)1.57957693
136Toxemia of pregnancy (HP:0100603)1.56850064
137Bulbar palsy (HP:0001283)1.55625788
138Ketoacidosis (HP:0001993)1.55110850
139Aortic aneurysm (HP:0004942)1.46770747

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TTN4.70622726
2OBSCN4.00558142
3DMPK3.14906411
4PHKG23.08842012
5PHKG13.08842012
6AKT32.69524576
7PDK42.54487418
8PDK32.54487418
9LMTK22.18757855
10TRIB31.96755837
11RIPK11.79613764
12INSRR1.76537364
13PIK3CA1.75122078
14MAP3K71.69136042
15MST1R1.60382138
16PDK21.53665181
17NTRK31.50611266
18STK381.50032406
19MET1.47750761
20CAMK1G1.47203263
21MAP3K41.41839997
22PKN21.39619843
23MAP2K41.35278526
24PRKD31.32578427
25BMPR1B1.30175327
26MYLK1.26677347
27LATS11.13603080
28SGK31.11278472
29TAOK31.10992342
30FER1.08595437
31JAK11.07243432
32MUSK1.06698335
33DDR21.05883091
34PTK2B1.05326049
35STK241.03869634
36PIK3CG1.01927701
37SGK21.01652197
38CDC42BPA1.00362950
39CAMK1D0.98265023
40TRPM70.98075090
41MAPK120.97785055
42TIE10.97558534
43PINK10.97326219
44ADRBK20.96471685
45EPHA20.94912373
46MAP3K20.92912768
47EPHA40.92568542
48PDGFRA0.92545087
49MAPK70.92175087
50ACVR1B0.91827311
51PTK60.89557764
52MAPK150.89483767
53PNCK0.89113046
54MAP3K90.87977898
55PRKCH0.87464959
56PRKAA20.86965497
57STK390.86815667
58MAP2K30.86288191
59ADRBK10.85204823
60TGFBR20.84717880
61CAMK40.82834167
62PAK30.82287079
63DAPK20.82161537
64FGFR30.81631517
65TGFBR10.81171246
66NME10.80954227
67RIPK40.80489522
68MARK10.80122647
69PRKD10.79946209
70WNK10.79330424
71SIK20.79281852
72MTOR0.79245677
73LATS20.79219091
74CAMK10.78966085
75PTK20.77179130
76SGK10.77171252
77PRKAA10.73314298
78ROCK10.73153621
79CAMKK20.72849687
80FRK0.72550408
81CAMK2D0.72278445
82GRK70.71857369
83MAP2K10.71542203
84MAP3K50.70500262
85PDK10.70245786
86CAMKK10.68932937
87CAMK2A0.64470563
88CHUK0.64313685
89ZAK0.64111144
90STK110.63147893
91RET0.63056701
92MARK20.63035721
93PDPK10.61953071
94SIK10.60973669
95PRKD20.59460794
96CDK120.59451213
97CAMK2G0.59002645
98NEK90.57270892
99TAOK10.55805544
100PAK60.55791078
101EPHB20.55764887
102PRKCE0.54618830
103PDGFRB0.53806292
104STK30.53727843
105ICK0.53433098
106STK38L0.51782937
107CAMK2B0.51742910
108MAP3K130.51362221
109EEF2K0.49990415
110NTRK20.49496893
111MELK0.49427900
112MAP2K70.49113766
113PLK20.48245871
114PAK20.47478056
115SGK4940.45924981
116SGK2230.45924981
117WNK40.45666833
118NLK0.45637387
119RPS6KA60.44813437
120CDK50.44434103
121ERBB30.43450406
122MINK10.42672621
123ABL20.42297990
124RPS6KA30.41928056
125MAP2K60.41121398
126EPHA30.40408219
127MAP3K60.39740000
128PRKG10.39601164
129MAP3K30.38165153
130MAPKAPK30.36995018
131RPS6KA20.36511200
132NEK10.36072522
133PRKACB0.34427337
134MAP3K10.33009715
135EPHB10.32432605

Predicted pathways (KEGG)

RankGene SetZ-score
1Dilated cardiomyopathy_Homo sapiens_hsa054142.88217406
2Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054102.74437020
3Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.40261957
4Cardiac muscle contraction_Homo sapiens_hsa042602.17153400
5Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.01837059
6Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.90198680
7Oxytocin signaling pathway_Homo sapiens_hsa049211.66164394
8Circadian entrainment_Homo sapiens_hsa047131.64232095
9Type II diabetes mellitus_Homo sapiens_hsa049301.63451990
10Renin secretion_Homo sapiens_hsa049241.61551833
11Long-term potentiation_Homo sapiens_hsa047201.58425429
12Insulin secretion_Homo sapiens_hsa049111.56228100
13Calcium signaling pathway_Homo sapiens_hsa040201.56147226
14Gastric acid secretion_Homo sapiens_hsa049711.52854780
15Nicotine addiction_Homo sapiens_hsa050331.52296077
16cGMP-PKG signaling pathway_Homo sapiens_hsa040221.50193336
17Aldosterone synthesis and secretion_Homo sapiens_hsa049251.48671543
18alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.47141240
19Olfactory transduction_Homo sapiens_hsa047401.39922016
20Linoleic acid metabolism_Homo sapiens_hsa005911.39313805
21Salivary secretion_Homo sapiens_hsa049701.38248724
22ABC transporters_Homo sapiens_hsa020101.35845289
23Glucagon signaling pathway_Homo sapiens_hsa049221.34544650
24Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.34437372
25Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29815562
26Amphetamine addiction_Homo sapiens_hsa050311.26616546
27Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.23062421
28GnRH signaling pathway_Homo sapiens_hsa049121.21355566
29Glutamatergic synapse_Homo sapiens_hsa047241.19657481
30Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.19240318
31Morphine addiction_Homo sapiens_hsa050321.18104636
32Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.17902455
33Insulin resistance_Homo sapiens_hsa049311.17472349
34cAMP signaling pathway_Homo sapiens_hsa040241.16715834
35Vascular smooth muscle contraction_Homo sapiens_hsa042701.16584437
36Cholinergic synapse_Homo sapiens_hsa047251.15568882
37Phosphatidylinositol signaling system_Homo sapiens_hsa040701.13439724
38Longevity regulating pathway - multiple species_Homo sapiens_hsa042131.12446249
39Viral myocarditis_Homo sapiens_hsa054161.09665217
40Taste transduction_Homo sapiens_hsa047421.06873272
41Dorso-ventral axis formation_Homo sapiens_hsa043201.06203408
42Insulin signaling pathway_Homo sapiens_hsa049101.05503595
43Histidine metabolism_Homo sapiens_hsa003401.04578141
44Nitrogen metabolism_Homo sapiens_hsa009101.03448021
45GABAergic synapse_Homo sapiens_hsa047271.01108249
46Adipocytokine signaling pathway_Homo sapiens_hsa049200.99592423
47Synaptic vesicle cycle_Homo sapiens_hsa047210.99042363
48Circadian rhythm_Homo sapiens_hsa047100.97227973
49Dopaminergic synapse_Homo sapiens_hsa047280.97082690
50Focal adhesion_Homo sapiens_hsa045100.95553341
51Estrogen signaling pathway_Homo sapiens_hsa049150.93637902
52Thyroid hormone signaling pathway_Homo sapiens_hsa049190.90153810
532-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.89307135
54Pancreatic secretion_Homo sapiens_hsa049720.88061759
55Long-term depression_Homo sapiens_hsa047300.87497200
56Adherens junction_Homo sapiens_hsa045200.86433206
57Longevity regulating pathway - mammal_Homo sapiens_hsa042110.86181007
58Propanoate metabolism_Homo sapiens_hsa006400.85266295
59MAPK signaling pathway_Homo sapiens_hsa040100.78435581
60Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.77265221
61AMPK signaling pathway_Homo sapiens_hsa041520.76651861
62VEGF signaling pathway_Homo sapiens_hsa043700.76539152
63Ether lipid metabolism_Homo sapiens_hsa005650.76037935
64Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.75060443
65Glioma_Homo sapiens_hsa052140.74840035
66Platelet activation_Homo sapiens_hsa046110.73299888
67Carbohydrate digestion and absorption_Homo sapiens_hsa049730.72179465
68TNF signaling pathway_Homo sapiens_hsa046680.71854964
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.71534757
70Phototransduction_Homo sapiens_hsa047440.71504318
71Gap junction_Homo sapiens_hsa045400.70863832
72Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.69324479
73Inositol phosphate metabolism_Homo sapiens_hsa005620.68694667
74mTOR signaling pathway_Homo sapiens_hsa041500.68455827
75Fatty acid degradation_Homo sapiens_hsa000710.68299962
76Jak-STAT signaling pathway_Homo sapiens_hsa046300.67798917
77Amoebiasis_Homo sapiens_hsa051460.67460407
78Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.65462242
79Proteoglycans in cancer_Homo sapiens_hsa052050.65342386
80Osteoclast differentiation_Homo sapiens_hsa043800.64831805
81AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.64365890
82Serotonergic synapse_Homo sapiens_hsa047260.64172978
83HIF-1 signaling pathway_Homo sapiens_hsa040660.63666262
84PPAR signaling pathway_Homo sapiens_hsa033200.63033604
85Sphingolipid metabolism_Homo sapiens_hsa006000.62574310
86Axon guidance_Homo sapiens_hsa043600.62064977
87Melanogenesis_Homo sapiens_hsa049160.61482810
88Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.61240166
89Bile secretion_Homo sapiens_hsa049760.61170951
90Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.61073906
91Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.59838183
92Cocaine addiction_Homo sapiens_hsa050300.59605901
93ErbB signaling pathway_Homo sapiens_hsa040120.58854225
94ECM-receptor interaction_Homo sapiens_hsa045120.57903213
95Melanoma_Homo sapiens_hsa052180.57420662
96Phospholipase D signaling pathway_Homo sapiens_hsa040720.57038535
97Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.56769790
98Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56705129
99Rap1 signaling pathway_Homo sapiens_hsa040150.56491204
100Neurotrophin signaling pathway_Homo sapiens_hsa047220.56256620
101FoxO signaling pathway_Homo sapiens_hsa040680.56064774
102Toxoplasmosis_Homo sapiens_hsa051450.55887202
103Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.55656360
104Hippo signaling pathway_Homo sapiens_hsa043900.54703406
105Tight junction_Homo sapiens_hsa045300.54422232
106Lysine degradation_Homo sapiens_hsa003100.54377515
107Leukocyte transendothelial migration_Homo sapiens_hsa046700.53406983
108Protein digestion and absorption_Homo sapiens_hsa049740.53327347
109Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.53148150
110Small cell lung cancer_Homo sapiens_hsa052220.52351141
111Ovarian steroidogenesis_Homo sapiens_hsa049130.52048172
112TGF-beta signaling pathway_Homo sapiens_hsa043500.51622669
113Renal cell carcinoma_Homo sapiens_hsa052110.50487946
114Arachidonic acid metabolism_Homo sapiens_hsa005900.50312931
115Fatty acid biosynthesis_Homo sapiens_hsa000610.50213448
116PI3K-Akt signaling pathway_Homo sapiens_hsa041510.50136854
117Primary bile acid biosynthesis_Homo sapiens_hsa001200.49476312
118Prolactin signaling pathway_Homo sapiens_hsa049170.49298919
119Thyroid hormone synthesis_Homo sapiens_hsa049180.48586006
120Endometrial cancer_Homo sapiens_hsa052130.48156223
121Choline metabolism in cancer_Homo sapiens_hsa052310.46487967
122Alzheimers disease_Homo sapiens_hsa050100.46091973
123Starch and sucrose metabolism_Homo sapiens_hsa005000.44733331
124Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.44581373
125Fatty acid metabolism_Homo sapiens_hsa012120.43105569
126Ras signaling pathway_Homo sapiens_hsa040140.42260987
127Collecting duct acid secretion_Homo sapiens_hsa049660.39550047

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