

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | regulation of T-helper 1 cell differentiation (GO:0045625) | 4.93301457 |
| 2 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.83090879 |
| 3 | positive regulation of granulocyte macrophage colony-stimulating factor production (GO:0032725) | 4.82736495 |
| 4 | regulation of vitamin D biosynthetic process (GO:0060556) | 4.68929025 |
| 5 | positive regulation of gamma-delta T cell activation (GO:0046645) | 4.64262245 |
| 6 | cellular response to type I interferon (GO:0071357) | 4.55689843 |
| 7 | type I interferon signaling pathway (GO:0060337) | 4.55689843 |
| 8 | response to type I interferon (GO:0034340) | 4.53761303 |
| 9 | detection of bacterium (GO:0016045) | 4.51417243 |
| 10 | regulation of vitamin metabolic process (GO:0030656) | 4.50557729 |
| 11 | T-helper 1 type immune response (GO:0042088) | 4.50548510 |
| 12 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 4.40206135 |
| 13 | detection of other organism (GO:0098543) | 4.39948910 |
| 14 | peptidyl-tyrosine autophosphorylation (GO:0038083) | 4.33510934 |
| 15 | regulation of granulocyte macrophage colony-stimulating factor production (GO:0032645) | 4.30098542 |
| 16 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 4.27703384 |
| 17 | myeloid dendritic cell differentiation (GO:0043011) | 4.21422480 |
| 18 | defense response to protozoan (GO:0042832) | 4.21025381 |
| 19 | NIK/NF-kappaB signaling (GO:0038061) | 4.14540286 |
| 20 | positive regulation of T-helper cell differentiation (GO:0045624) | 4.14520840 |
| 21 | response to protozoan (GO:0001562) | 4.07764164 |
| 22 | positive regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043372) | 3.99174075 |
| 23 | negative regulation of interleukin-12 production (GO:0032695) | 3.93272499 |
| 24 | regulation of T-helper cell differentiation (GO:0045622) | 3.91381373 |
| 25 | regulation of antigen processing and presentation (GO:0002577) | 3.85043290 |
| 26 | oligosaccharide catabolic process (GO:0009313) | 3.83749309 |
| 27 | interferon-gamma-mediated signaling pathway (GO:0060333) | 3.82879882 |
| 28 | regulation of interferon-alpha production (GO:0032647) | 3.79759470 |
| 29 | immunoglobulin mediated immune response (GO:0016064) | 3.78426768 |
| 30 | myeloid dendritic cell activation (GO:0001773) | 3.74530498 |
| 31 | regulation of natural killer cell differentiation (GO:0032823) | 3.69911593 |
| 32 | regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043370) | 3.65647447 |
| 33 | positive regulation of interferon-gamma biosynthetic process (GO:0045078) | 3.64659186 |
| 34 | glycosphingolipid catabolic process (GO:0046479) | 3.62518351 |
| 35 | regulation of cytokine secretion involved in immune response (GO:0002739) | 3.60061009 |
| 36 | response to peptidoglycan (GO:0032494) | 3.58353053 |
| 37 | phosphate ion transport (GO:0006817) | 3.57210430 |
| 38 | CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369) | 3.53900508 |
| 39 | positive regulation of type 2 immune response (GO:0002830) | 3.52297247 |
| 40 | lipopolysaccharide-mediated signaling pathway (GO:0031663) | 3.51225585 |
| 41 | regulation of natural killer cell activation (GO:0032814) | 3.50870443 |
| 42 | positive regulation of CD4-positive, alpha-beta T cell activation (GO:2000516) | 3.45709846 |
| 43 | regulation of chronic inflammatory response (GO:0002676) | 3.45117730 |
| 44 | macrophage activation involved in immune response (GO:0002281) | 3.42574894 |
| 45 | regulation of interferon-gamma biosynthetic process (GO:0045072) | 3.38317634 |
| 46 | positive regulation of interferon-alpha production (GO:0032727) | 3.37060662 |
| 47 | dendritic cell differentiation (GO:0097028) | 3.36226995 |
| 48 | regulation of dendritic cell antigen processing and presentation (GO:0002604) | 3.34892111 |
| 49 | positive regulation of interleukin-17 production (GO:0032740) | 3.34487794 |
| 50 | positive regulation of heat generation (GO:0031652) | 3.32959044 |
| 51 | detection of external biotic stimulus (GO:0098581) | 3.31697818 |
| 52 | regulation of fever generation (GO:0031620) | 3.31633251 |
| 53 | positive regulation of defense response to virus by host (GO:0002230) | 3.31155001 |
| 54 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.28845097 |
| 55 | glycolipid catabolic process (GO:0019377) | 3.24844038 |
| 56 | regulation of interleukin-12 production (GO:0032655) | 3.17622312 |
| 57 | positive regulation of antigen processing and presentation (GO:0002579) | 3.17607409 |
| 58 | regulation of CD4-positive, alpha-beta T cell activation (GO:2000514) | 3.17034779 |
| 59 | positive regulation of NF-kappaB import into nucleus (GO:0042346) | 3.15949918 |
| 60 | response to thyroid hormone (GO:0097066) | 3.15515359 |
| 61 | positive regulation of interleukin-12 production (GO:0032735) | 3.12999016 |
| 62 | negative regulation of myeloid cell apoptotic process (GO:0033033) | 3.12328637 |
| 63 | cellular response to interferon-gamma (GO:0071346) | 3.11646687 |
| 64 | negative regulation of viral genome replication (GO:0045071) | 3.10101239 |
| 65 | positive regulation of humoral immune response (GO:0002922) | 3.09341269 |
| 66 | regulation of gamma-delta T cell activation (GO:0046643) | 3.09067465 |
| 67 | fat-soluble vitamin biosynthetic process (GO:0042362) | 3.08026447 |
| 68 | histone H2A acetylation (GO:0043968) | 3.07679081 |
| 69 | energy homeostasis (GO:0097009) | 3.06367771 |
| 70 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 3.03719257 |
| 71 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 3.03625489 |
| 72 | positive regulation of chemokine biosynthetic process (GO:0045080) | 3.00912204 |
| 73 | urate metabolic process (GO:0046415) | 3.00788782 |
| 74 | T cell migration (GO:0072678) | 3.00008631 |
| 75 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.98619340 |
| 76 | response to interferon-gamma (GO:0034341) | 2.96972263 |
| 77 | detection of biotic stimulus (GO:0009595) | 2.94050687 |
| 78 | negative regulation of nitric oxide biosynthetic process (GO:0045019) | 2.93645628 |
| 79 | positive regulation by symbiont of host defense response (GO:0052509) | 2.93267698 |
| 80 | modulation by symbiont of host defense response (GO:0052031) | 2.93267698 |
| 81 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 2.93267698 |
| 82 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 2.93267698 |
| 83 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 2.93267698 |
| 84 | modulation by symbiont of host immune response (GO:0052553) | 2.93267698 |
| 85 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 2.93258569 |
| 86 | B cell mediated immunity (GO:0019724) | 2.91855171 |
| 87 | positive regulation of B cell differentiation (GO:0045579) | 2.90332187 |
| 88 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.88120964 |
| 89 | positive regulation of natural killer cell activation (GO:0032816) | 2.88007742 |
| 90 | positive regulation of syncytium formation by plasma membrane fusion (GO:0060143) | 2.87369327 |
| 91 | ceramide catabolic process (GO:0046514) | 2.86859287 |
| 92 | negative regulation of inflammatory response to antigenic stimulus (GO:0002862) | 2.86595462 |
| 93 | negative regulation of cytokine production involved in immune response (GO:0002719) | 2.83819940 |
| 94 | regulation of podosome assembly (GO:0071801) | 2.83649112 |
| 95 | regulation of T-helper 1 type immune response (GO:0002825) | 2.81643004 |
| 96 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.78516642 |
| 97 | mature B cell differentiation involved in immune response (GO:0002313) | 2.78142787 |
| 98 | monocyte chemotaxis (GO:0002548) | 2.77151673 |
| 99 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.74789955 |
| 100 | positive regulation of interleukin-10 production (GO:0032733) | 2.73341820 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 7.63365284 |
| 2 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 5.40548953 |
| 3 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 3.99918407 |
| 4 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 3.74300382 |
| 5 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 3.64770505 |
| 6 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.44714840 |
| 7 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 2.94539785 |
| 8 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.93979487 |
| 9 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 2.93759140 |
| 10 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 2.75661166 |
| 11 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.71245987 |
| 12 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.70111422 |
| 13 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 2.55007686 |
| 14 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 2.48693678 |
| 15 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 2.36803179 |
| 16 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.31766744 |
| 17 | VDR_21846776_ChIP-Seq_THP-1_Human | 2.27392014 |
| 18 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.25391079 |
| 19 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 2.19792785 |
| 20 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.04481503 |
| 21 | * E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 2.02899064 |
| 22 | GATA1_22025678_ChIP-Seq_K562_Human | 10.2385528 |
| 23 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.94762426 |
| 24 | * NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human | 1.86120033 |
| 25 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.76937248 |
| 26 | VDR_24763502_ChIP-Seq_THP-1_Human | 1.75044093 |
| 27 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.73130414 |
| 28 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.71385197 |
| 29 | MYB_26560356_Chip-Seq_TH2_Human | 1.70330797 |
| 30 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.70132608 |
| 31 | MYC_22102868_ChIP-Seq_BL_Human | 1.68735245 |
| 32 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 1.58218905 |
| 33 | BRD4_27068464_Chip-Seq_AML-cells_Mouse | 1.57605560 |
| 34 | SPI1_23127762_ChIP-Seq_K562_Human | 1.54861147 |
| 35 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.53838120 |
| 36 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50333845 |
| 37 | MAF_26560356_Chip-Seq_TH1_Human | 1.50114228 |
| 38 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.49517909 |
| 39 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 1.44509251 |
| 40 | PU_27001747_Chip-Seq_BMDM_Mouse | 1.40009436 |
| 41 | RUNX1_22412390_ChIP-Seq_EML_Mouse | 1.31859918 |
| 42 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.31084413 |
| 43 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27023493 |
| 44 | CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.26366929 |
| 45 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.24083391 |
| 46 | GATA3_26560356_Chip-Seq_TH2_Human | 1.23937207 |
| 47 | STAT1_20625510_ChIP-Seq_HELA_Human | 1.23921507 |
| 48 | CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.20302841 |
| 49 | UTX_26944678_Chip-Seq_JUKART_Human | 1.18638100 |
| 50 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.18495156 |
| 51 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.17975162 |
| 52 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 1.16868820 |
| 53 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14598906 |
| 54 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 1.12304905 |
| 55 | PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.10792087 |
| 56 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.10085615 |
| 57 | VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human | 1.09468917 |
| 58 | CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse | 1.08711279 |
| 59 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.05279259 |
| 60 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.03703475 |
| 61 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.03547101 |
| 62 | SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 1.02488348 |
| 63 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.98908453 |
| 64 | GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.97869736 |
| 65 | GATA3_27048872_Chip-Seq_THYMUS_Human | 0.97301379 |
| 66 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.95713489 |
| 67 | PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse | 0.95565269 |
| 68 | MYB_26560356_Chip-Seq_TH1_Human | 0.95243346 |
| 69 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.94083755 |
| 70 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.94004207 |
| 71 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.93369171 |
| 72 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.93191628 |
| 73 | TCF7_22412390_ChIP-Seq_EML_Mouse | 0.92669923 |
| 74 | PU.1_20513432_ChIP-Seq_Bcells_Mouse | 0.92221617 |
| 75 | SMRT_27268052_Chip-Seq_Bcells_Human | 0.91385630 |
| 76 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.89574439 |
| 77 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.86711620 |
| 78 | GATA1_19941826_ChIP-Seq_K562_Human | 0.85001145 |
| 79 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.84600504 |
| 80 | SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.84444908 |
| 81 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 0.80790473 |
| 82 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.78418066 |
| 83 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78100792 |
| 84 | MAF_26560356_Chip-Seq_TH2_Human | 0.77474014 |
| 85 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.75508755 |
| 86 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.75493794 |
| 87 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.74596024 |
| 88 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.74593272 |
| 89 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.72639153 |
| 90 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.69599914 |
| 91 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.68067160 |
| 92 | KDM2B_26808549_Chip-Seq_DND41_Human | 0.65733603 |
| 93 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.64548166 |
| 94 | ESET_19884257_ChIP-Seq_ESCs_Mouse | 0.63559014 |
| 95 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.62580924 |
| 96 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.61203594 |
| 97 | GATA2_19941826_ChIP-Seq_K562_Human | 0.61079133 |
| 98 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 0.56468791 |
| 99 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.56254410 |
| 100 | GATA1_19941827_ChIP-Seq_MEL86_Mouse | 0.55864185 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003303_peritoneal_inflammation | 4.89513438 |
| 2 | MP0004510_myositis | 3.84640516 |
| 3 | MP0002148_abnormal_hypersensitivity_rea | 3.35715758 |
| 4 | MP0009785_altered_susceptibility_to | 3.28453239 |
| 5 | MP0001790_abnormal_immune_system | 3.27901547 |
| 6 | MP0005387_immune_system_phenotype | 3.27901547 |
| 7 | MP0001835_abnormal_antigen_presentation | 3.22599624 |
| 8 | MP0005671_abnormal_response_to | 3.19086112 |
| 9 | MP0006082_CNS_inflammation | 3.08986058 |
| 10 | MP0005000_abnormal_immune_tolerance | 2.86625356 |
| 11 | MP0005397_hematopoietic_system_phenotyp | 2.72846966 |
| 12 | MP0001545_abnormal_hematopoietic_system | 2.72846966 |
| 13 | MP0001800_abnormal_humoral_immune | 2.71179028 |
| 14 | MP0003436_decreased_susceptibility_to | 2.63991085 |
| 15 | MP0003724_increased_susceptibility_to | 2.54620043 |
| 16 | MP0002452_abnormal_antigen_presenting | 2.53050094 |
| 17 | MP0005025_abnormal_response_to | 2.52433500 |
| 18 | MP0002138_abnormal_hepatobiliary_system | 2.42183761 |
| 19 | MP0002723_abnormal_immune_serum | 2.41289215 |
| 20 | MP0002419_abnormal_innate_immunity | 2.36025660 |
| 21 | MP0002139_abnormal_hepatobiliary_system | 2.30214314 |
| 22 | MP0005058_abnormal_lysosome_morphology | 2.28697346 |
| 23 | MP0000685_abnormal_immune_system | 2.28410351 |
| 24 | MP0003300_gastrointestinal_ulcer | 2.24542262 |
| 25 | MP0004947_skin_inflammation | 2.08646876 |
| 26 | MP0002420_abnormal_adaptive_immunity | 2.00284114 |
| 27 | MP0001819_abnormal_immune_cell | 2.00179471 |
| 28 | MP0009333_abnormal_splenocyte_physiolog | 1.93790007 |
| 29 | MP0009840_abnormal_foam_cell | 1.91916082 |
| 30 | MP0005310_abnormal_salivary_gland | 1.89503720 |
| 31 | MP0000604_amyloidosis | 1.88563287 |
| 32 | MP0009764_decreased_sensitivity_to | 1.84309240 |
| 33 | MP0001845_abnormal_inflammatory_respons | 1.81337998 |
| 34 | MP0002332_abnormal_exercise_endurance | 1.81296702 |
| 35 | MP0009278_abnormal_bone_marrow | 1.80062931 |
| 36 | MP0003075_altered_response_to | 1.78855681 |
| 37 | MP0001853_heart_inflammation | 1.77216729 |
| 38 | MP0002405_respiratory_system_inflammati | 1.73548481 |
| 39 | MP0008469_abnormal_protein_level | 1.65986892 |
| 40 | MP0010155_abnormal_intestine_physiology | 1.65854856 |
| 41 | MP0003763_abnormal_thymus_physiology | 1.64599332 |
| 42 | MP0003172_abnormal_lysosome_physiology | 1.53082011 |
| 43 | MP0005464_abnormal_platelet_physiology | 1.51040282 |
| 44 | MP0005451_abnormal_body_composition | 1.49894910 |
| 45 | MP0000716_abnormal_immune_system | 1.49640953 |
| 46 | MP0000343_altered_response_to | 1.48632453 |
| 47 | MP0004808_abnormal_hematopoietic_stem | 1.47625144 |
| 48 | MP0001533_abnormal_skeleton_physiology | 1.45458438 |
| 49 | MP0002398_abnormal_bone_marrow | 1.41029622 |
| 50 | MP0008004_abnormal_stomach_pH | 1.39106925 |
| 51 | MP0003195_calcinosis | 1.37049301 |
| 52 | MP0005166_decreased_susceptibility_to | 1.32267045 |
| 53 | MP0003045_fibrosis | 1.30886560 |
| 54 | MP0002254_reproductive_system_inflammat | 1.30732212 |
| 55 | MP0003191_abnormal_cellular_cholesterol | 1.30190165 |
| 56 | MP0003453_abnormal_keratinocyte_physiol | 1.23351402 |
| 57 | MP0005167_abnormal_blood-brain_barrier | 1.19920024 |
| 58 | MP0003806_abnormal_nucleotide_metabolis | 1.19689972 |
| 59 | MP0002429_abnormal_blood_cell | 1.14830532 |
| 60 | MP0001873_stomach_inflammation | 1.12948613 |
| 61 | MP0002998_abnormal_bone_remodeling | 1.12275597 |
| 62 | MP0003183_abnormal_peptide_metabolism | 1.11434886 |
| 63 | MP0000689_abnormal_spleen_morphology | 1.09051696 |
| 64 | MP0009765_abnormal_xenobiotic_induced | 1.07783403 |
| 65 | MP0001348_abnormal_lacrimal_gland | 1.05699917 |
| 66 | MP0002722_abnormal_immune_system | 1.01269755 |
| 67 | MP0003448_altered_tumor_morphology | 0.98461757 |
| 68 | MP0005647_abnormal_sex_gland | 0.96578363 |
| 69 | MP0000858_altered_metastatic_potential | 0.96226322 |
| 70 | MP0009763_increased_sensitivity_to | 0.93279007 |
| 71 | MP0005165_increased_susceptibility_to | 0.92476266 |
| 72 | MP0003878_abnormal_ear_physiology | 0.90717239 |
| 73 | MP0005377_hearing/vestibular/ear_phenot | 0.90717239 |
| 74 | MP0001501_abnormal_sleep_pattern | 0.86752208 |
| 75 | MP0005319_abnormal_enzyme/_coenzyme | 0.86597614 |
| 76 | MP0003690_abnormal_glial_cell | 0.83428836 |
| 77 | MP0005645_abnormal_hypothalamus_physiol | 0.81875619 |
| 78 | MP0006054_spinal_hemorrhage | 0.79467493 |
| 79 | MP0004019_abnormal_vitamin_homeostasis | 0.78902312 |
| 80 | MP0001663_abnormal_digestive_system | 0.76546753 |
| 81 | MP0003656_abnormal_erythrocyte_physiolo | 0.73623919 |
| 82 | MP0003646_muscle_fatigue | 0.66125410 |
| 83 | MP0008874_decreased_physiological_sensi | 0.65372714 |
| 84 | MP0001764_abnormal_homeostasis | 0.62002621 |
| 85 | MP0003091_abnormal_cell_migration | 0.61512300 |
| 86 | MP0000465_gastrointestinal_hemorrhage | 0.61403107 |
| 87 | MP0005164_abnormal_response_to | 0.59871635 |
| 88 | MP0002693_abnormal_pancreas_physiology | 0.57161263 |
| 89 | MP0003795_abnormal_bone_structure | 0.56495045 |
| 90 | MP0005379_endocrine/exocrine_gland_phen | 0.52201775 |
| 91 | MP0002136_abnormal_kidney_physiology | 0.52057081 |
| 92 | MP0010307_abnormal_tumor_latency | 0.51946713 |
| 93 | MP0005257_abnormal_intraocular_pressure | 0.51468044 |
| 94 | MP0000920_abnormal_myelination | 0.51353483 |
| 95 | MP0005266_abnormal_metabolism | 0.50972953 |
| 96 | MP0000249_abnormal_blood_vessel | 0.49711243 |
| 97 | MP0002006_tumorigenesis | 0.48799391 |
| 98 | MP0000609_abnormal_liver_physiology | 0.48129916 |
| 99 | MP0009643_abnormal_urine_homeostasis | 0.47283961 |
| 100 | MP0000703_abnormal_thymus_morphology | 0.45848808 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Generalized aminoaciduria (HP:0002909) | 6.67417731 |
| 2 | Abnormality of liposaccharide metabolism (HP:0010968) | 5.56946555 |
| 3 | Abnormality of glycosphingolipid metabolism (HP:0004343) | 5.56946555 |
| 4 | Abnormality of glycolipid metabolism (HP:0010969) | 5.56946555 |
| 5 | Recurrent bacterial skin infections (HP:0005406) | 4.39091289 |
| 6 | Abnormality of macrophages (HP:0004311) | 4.26462268 |
| 7 | Mediastinal lymphadenopathy (HP:0100721) | 4.12576117 |
| 8 | Gastrointestinal stroma tumor (HP:0100723) | 4.10886439 |
| 9 | Autoimmune thrombocytopenia (HP:0001973) | 4.04754907 |
| 10 | Recurrent abscess formation (HP:0002722) | 3.95971715 |
| 11 | Eczematoid dermatitis (HP:0000976) | 3.89272004 |
| 12 | Dysostosis multiplex (HP:0000943) | 3.71272498 |
| 13 | Vacuolated lymphocytes (HP:0001922) | 3.70156631 |
| 14 | Increased cerebral lipofuscin (HP:0011813) | 3.63216445 |
| 15 | Retrobulbar optic neuritis (HP:0100654) | 3.53164990 |
| 16 | Optic neuritis (HP:0100653) | 3.53164990 |
| 17 | Disinhibition (HP:0000734) | 3.43904045 |
| 18 | Parakeratosis (HP:0001036) | 3.40157163 |
| 19 | Vasculitis (HP:0002633) | 3.38453295 |
| 20 | Recurrent sinusitis (HP:0011108) | 3.37008827 |
| 21 | Severe visual impairment (HP:0001141) | 3.36108878 |
| 22 | Proximal tubulopathy (HP:0000114) | 3.35937846 |
| 23 | Recurrent viral infections (HP:0004429) | 3.26504749 |
| 24 | Systemic lupus erythematosus (HP:0002725) | 3.26182132 |
| 25 | Stomatitis (HP:0010280) | 3.23322404 |
| 26 | Orchitis (HP:0100796) | 3.16968748 |
| 27 | Loss of speech (HP:0002371) | 3.16086681 |
| 28 | IgA deficiency (HP:0002720) | 3.15274717 |
| 29 | Meningitis (HP:0001287) | 3.10963940 |
| 30 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.05997333 |
| 31 | Increased IgM level (HP:0003496) | 3.05272723 |
| 32 | Colitis (HP:0002583) | 2.98397796 |
| 33 | Increased serum ferritin (HP:0003281) | 2.93683682 |
| 34 | Agnosia (HP:0010524) | 2.88706362 |
| 35 | Nausea (HP:0002018) | 2.88272236 |
| 36 | Increased neuronal autofluorescent lipopigment (HP:0002074) | 2.87676823 |
| 37 | Recurrent bronchitis (HP:0002837) | 2.83699157 |
| 38 | Pulmonary infiltrates (HP:0002113) | 2.79173612 |
| 39 | Myositis (HP:0100614) | 2.79018200 |
| 40 | Pendular nystagmus (HP:0012043) | 2.77117669 |
| 41 | Restrictive lung disease (HP:0002091) | 2.76379537 |
| 42 | IgM deficiency (HP:0002850) | 2.75888394 |
| 43 | Abnormality of B cell number (HP:0010975) | 2.72990684 |
| 44 | Agammaglobulinemia (HP:0004432) | 2.68506010 |
| 45 | Recurrent pneumonia (HP:0006532) | 2.61311444 |
| 46 | Abnormality of mucopolysaccharide metabolism (HP:0011020) | 2.60553048 |
| 47 | Abnormality of polysaccharide metabolism (HP:0011012) | 2.60553048 |
| 48 | Abnormality of glycosaminoglycan metabolism (HP:0004371) | 2.60553048 |
| 49 | Mucopolysacchariduria (HP:0008155) | 2.60385660 |
| 50 | Urinary glycosaminoglycan excretion (HP:0003541) | 2.60385660 |
| 51 | Gangrene (HP:0100758) | 2.58128653 |
| 52 | Lymphopenia (HP:0001888) | 2.56492160 |
| 53 | Obstructive lung disease (HP:0006536) | 2.55099873 |
| 54 | Chronic obstructive pulmonary disease (HP:0006510) | 2.55099873 |
| 55 | Recurrent fungal infections (HP:0002841) | 2.51761520 |
| 56 | Primitive reflexes (palmomental, snout, glabellar) (HP:0002476) | 2.46618202 |
| 57 | Recurrent skin infections (HP:0001581) | 2.44634492 |
| 58 | Autoimmune hemolytic anemia (HP:0001890) | 2.44082094 |
| 59 | Metaphyseal irregularity (HP:0003025) | 2.40470751 |
| 60 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 2.40005999 |
| 61 | Abnormality of iron homeostasis (HP:0011031) | 2.38874526 |
| 62 | B lymphocytopenia (HP:0010976) | 2.38757712 |
| 63 | Abnormality of T cell number (HP:0011839) | 2.35182954 |
| 64 | Basal ganglia calcification (HP:0002135) | 2.34876715 |
| 65 | Emphysema (HP:0002097) | 2.34701201 |
| 66 | Keratoconjunctivitis sicca (HP:0001097) | 2.33871525 |
| 67 | Mutism (HP:0002300) | 2.33693398 |
| 68 | Purpura (HP:0000979) | 2.28785515 |
| 69 | T lymphocytopenia (HP:0005403) | 2.26612804 |
| 70 | Inflammation of the large intestine (HP:0002037) | 2.23595938 |
| 71 | IgG deficiency (HP:0004315) | 2.22921227 |
| 72 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.19626407 |
| 73 | Hemoptysis (HP:0002105) | 2.18722684 |
| 74 | Cellulitis (HP:0100658) | 2.17404807 |
| 75 | Polyneuropathy (HP:0001271) | 2.17272978 |
| 76 | Nuclear cataract (HP:0100018) | 2.16845907 |
| 77 | Hematochezia (HP:0002573) | 2.16800315 |
| 78 | Hypergammaglobulinemia (HP:0010702) | 2.16388461 |
| 79 | Recurrent lower respiratory tract infections (HP:0002783) | 2.16371970 |
| 80 | Thoracic kyphosis (HP:0002942) | 2.13604567 |
| 81 | Encephalitis (HP:0002383) | 2.12871659 |
| 82 | J-shaped sella turcica (HP:0002680) | 2.12264453 |
| 83 | Keratoconjunctivitis (HP:0001096) | 2.11817186 |
| 84 | Chronic diarrhea (HP:0002028) | 2.09962127 |
| 85 | Urticaria (HP:0001025) | 2.09191218 |
| 86 | Neurofibrillary tangles (HP:0002185) | 2.08994037 |
| 87 | Gastrointestinal infarctions (HP:0005244) | 2.07487643 |
| 88 | Acute lymphatic leukemia (HP:0006721) | 2.06801917 |
| 89 | Increased IgE level (HP:0003212) | 2.06731538 |
| 90 | Abnormality of the prostate (HP:0008775) | 2.06443635 |
| 91 | Glomerulonephritis (HP:0000099) | 2.05512270 |
| 92 | Gastrointestinal inflammation (HP:0004386) | 2.05129555 |
| 93 | Malnutrition (HP:0004395) | 2.01033705 |
| 94 | Arthralgia (HP:0002829) | 2.00512824 |
| 95 | Abnormality of T cell physiology (HP:0011840) | 1.99208694 |
| 96 | Hepatosplenomegaly (HP:0001433) | 1.98828301 |
| 97 | Abnormality of T cells (HP:0002843) | 1.98366613 |
| 98 | Hypophosphatemia (HP:0002148) | 1.97408661 |
| 99 | Abnormality of the pleura (HP:0002103) | 1.93979483 |
| 100 | Vertigo (HP:0002321) | 1.93699725 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | NME2 | 4.00631234 |
| 2 | MAP4K1 | 3.93798032 |
| 3 | RIPK4 | 3.72357704 |
| 4 | IRAK3 | 3.40762073 |
| 5 | MAP3K14 | 3.02099131 |
| 6 | GRK7 | 2.95707094 |
| 7 | BLK | 2.92180225 |
| 8 | TXK | 2.85688767 |
| 9 | TBK1 | 2.50554792 |
| 10 | IKBKB | 2.37377418 |
| 11 | IKBKE | 2.33571780 |
| 12 | IRAK4 | 2.30856856 |
| 13 | MATK | 2.30409420 |
| 14 | DDR2 | 2.27959467 |
| 15 | TAOK2 | 2.26463179 |
| 16 | BMPR2 | 2.26436208 |
| 17 | PRPF4B | 2.16304572 |
| 18 | CDK19 | 2.09765156 |
| 19 | JAK3 | 2.09605748 |
| 20 | MOS | 2.03613862 |
| 21 | TYK2 | 1.96309802 |
| 22 | SYK | 1.92898827 |
| 23 | ADRBK2 | 1.86417176 |
| 24 | CSK | 1.80979385 |
| 25 | PIM2 | 1.78019493 |
| 26 | FGR | 1.64190854 |
| 27 | LYN | 1.48044116 |
| 28 | BTK | 1.46453911 |
| 29 | CSF1R | 1.39876505 |
| 30 | JAK1 | 1.39831299 |
| 31 | TGFBR2 | 1.30760961 |
| 32 | CHUK | 1.29631152 |
| 33 | ACVR1B | 1.26809405 |
| 34 | FRK | 1.20187847 |
| 35 | CDC42BPA | 1.15748358 |
| 36 | KIT | 1.09927352 |
| 37 | MAP3K11 | 1.06974963 |
| 38 | RIPK1 | 1.05448768 |
| 39 | JAK2 | 1.02822540 |
| 40 | TAOK3 | 1.01110383 |
| 41 | NEK9 | 1.01062343 |
| 42 | MAP3K13 | 1.00969183 |
| 43 | TAOK1 | 1.00534053 |
| 44 | STK10 | 0.95334828 |
| 45 | LCK | 0.94368337 |
| 46 | PIM1 | 0.90070782 |
| 47 | MAP3K3 | 0.89391107 |
| 48 | ZAP70 | 0.89367653 |
| 49 | MAPK4 | 0.84921059 |
| 50 | IRAK2 | 0.79991068 |
| 51 | HCK | 0.79095314 |
| 52 | MAP3K5 | 0.75719246 |
| 53 | HIPK2 | 0.75324283 |
| 54 | IRAK1 | 0.68893520 |
| 55 | MARK3 | 0.67871033 |
| 56 | TNK2 | 0.67027365 |
| 57 | TLK1 | 0.66009230 |
| 58 | PKN1 | 0.64319996 |
| 59 | DAPK3 | 0.59437994 |
| 60 | ARAF | 0.58301730 |
| 61 | PDK1 | 0.56799210 |
| 62 | SIK3 | 0.56481231 |
| 63 | MAP2K6 | 0.56188419 |
| 64 | INSR | 0.55821140 |
| 65 | MAPK7 | 0.55183471 |
| 66 | TYRO3 | 0.53991568 |
| 67 | ERN1 | 0.51562071 |
| 68 | AURKA | 0.51336195 |
| 69 | RPS6KL1 | 0.50976043 |
| 70 | RPS6KC1 | 0.50976043 |
| 71 | PRKCD | 0.48683272 |
| 72 | MAP2K3 | 0.47802200 |
| 73 | CDK4 | 0.47066078 |
| 74 | SIK2 | 0.46028083 |
| 75 | MAP3K1 | 0.44422507 |
| 76 | CDK6 | 0.44218011 |
| 77 | STK24 | 0.42183101 |
| 78 | RPS6KA6 | 0.41911514 |
| 79 | PDGFRA | 0.40740190 |
| 80 | ABL1 | 0.40497506 |
| 81 | ABL2 | 0.39650772 |
| 82 | EGFR | 0.37540050 |
| 83 | PDPK1 | 0.37530685 |
| 84 | TEC | 0.36089128 |
| 85 | FGFR3 | 0.33052152 |
| 86 | PRKCQ | 0.32855465 |
| 87 | FES | 0.32221601 |
| 88 | CCNB1 | 0.31845279 |
| 89 | DAPK2 | 0.31367203 |
| 90 | LATS2 | 0.28521043 |
| 91 | PRKCH | 0.26521623 |
| 92 | FYN | 0.25292283 |
| 93 | MAPK11 | 0.24626521 |
| 94 | LRRK2 | 0.23405772 |
| 95 | GRK5 | 0.22703049 |
| 96 | CDK12 | 0.21187355 |
| 97 | BCKDK | 0.20992905 |
| 98 | ITK | 0.20687580 |
| 99 | ALK | 0.19397522 |
| 100 | RPS6KA2 | 0.16883538 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 3.88190201 |
| 2 | Allograft rejection_Homo sapiens_hsa05330 | 3.82484464 |
| 3 | Asthma_Homo sapiens_hsa05310 | 3.68246378 |
| 4 | Graft-versus-host disease_Homo sapiens_hsa05332 | 3.28061718 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.23047286 |
| 6 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 2.75512248 |
| 7 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 2.75337269 |
| 8 | Leishmaniasis_Homo sapiens_hsa05140 | 2.70532402 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.70321518 |
| 10 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 2.53343921 |
| 11 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.48083032 |
| 12 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 2.43648490 |
| 13 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 2.33679017 |
| 14 | Other glycan degradation_Homo sapiens_hsa00511 | 2.18819356 |
| 15 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.17311694 |
| 16 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.05058477 |
| 17 | Tuberculosis_Homo sapiens_hsa05152 | 1.99142313 |
| 18 | African trypanosomiasis_Homo sapiens_hsa05143 | 1.97489905 |
| 19 | Renin-angiotensin system_Homo sapiens_hsa04614 | 1.87765109 |
| 20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.87340629 |
| 21 | Lysosome_Homo sapiens_hsa04142 | 1.80031313 |
| 22 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.79894503 |
| 23 | Influenza A_Homo sapiens_hsa05164 | 1.76404230 |
| 24 | Malaria_Homo sapiens_hsa05144 | 1.71770665 |
| 25 | Viral myocarditis_Homo sapiens_hsa05416 | 1.69004183 |
| 26 | Pertussis_Homo sapiens_hsa05133 | 1.63475211 |
| 27 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.60812586 |
| 28 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.60464185 |
| 29 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.59105442 |
| 30 | Toxoplasmosis_Homo sapiens_hsa05145 | 1.56360684 |
| 31 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.50195610 |
| 32 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.47350575 |
| 33 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.42679652 |
| 34 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.42287931 |
| 35 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.40552473 |
| 36 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.36641511 |
| 37 | Measles_Homo sapiens_hsa05162 | 1.35659392 |
| 38 | Legionellosis_Homo sapiens_hsa05134 | 1.34827276 |
| 39 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.23774757 |
| 40 | Salmonella infection_Homo sapiens_hsa05132 | 1.09997582 |
| 41 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.09548236 |
| 42 | Phagosome_Homo sapiens_hsa04145 | 1.09077062 |
| 43 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.07985879 |
| 44 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.96172337 |
| 45 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 0.91566912 |
| 46 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.85366632 |
| 47 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.84091171 |
| 48 | Hepatitis B_Homo sapiens_hsa05161 | 0.82970325 |
| 49 | Hepatitis C_Homo sapiens_hsa05160 | 0.82462070 |
| 50 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.74515222 |
| 51 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.73528647 |
| 52 | Apoptosis_Homo sapiens_hsa04210 | 0.71736939 |
| 53 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.64012889 |
| 54 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.60226232 |
| 55 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.53443913 |
| 56 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.52872204 |
| 57 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 0.52640517 |
| 58 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.52217585 |
| 59 | Shigellosis_Homo sapiens_hsa05131 | 0.51823521 |
| 60 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.50041767 |
| 61 | Prion diseases_Homo sapiens_hsa05020 | 0.50004850 |
| 62 | HTLV-I infection_Homo sapiens_hsa05166 | 0.48837457 |
| 63 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.44839523 |
| 64 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.42895886 |
| 65 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.42378835 |
| 66 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.39770640 |
| 67 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.39219728 |
| 68 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.37979053 |
| 69 | Amoebiasis_Homo sapiens_hsa05146 | 0.37441295 |
| 70 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.35962918 |
| 71 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.35378840 |
| 72 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.35350335 |
| 73 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.30836137 |
| 74 | Bladder cancer_Homo sapiens_hsa05219 | 0.29804580 |
| 75 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.25590441 |
| 76 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.25129684 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.22997572 |
| 78 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.21729169 |
| 79 | Sphingolipid signaling pathway_Homo sapiens_hsa04071 | 0.18761676 |
| 80 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.18712308 |
| 81 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.18419864 |
| 82 | Platelet activation_Homo sapiens_hsa04611 | 0.17086816 |
| 83 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.16604764 |
| 84 | Galactose metabolism_Homo sapiens_hsa00052 | 0.15604631 |
| 85 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.13605759 |
| 86 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.13498554 |
| 87 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.13468675 |
| 88 | Insulin resistance_Homo sapiens_hsa04931 | 0.13415438 |
| 89 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.13319179 |
| 90 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.11851144 |
| 91 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.11800860 |
| 92 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.11369456 |
| 93 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.09583171 |
| 94 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.08267607 |
| 95 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.08259556 |
| 96 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.06707503 |
| 97 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.03621021 |
| 98 | Phototransduction_Homo sapiens_hsa04744 | 0.03010413 |
| 99 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.02761811 |
| 100 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.02412184 |

