CMC1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.17179526
2polyketide metabolic process (GO:0030638)6.06456781
3doxorubicin metabolic process (GO:0044598)6.06456781
4daunorubicin metabolic process (GO:0044597)6.06456781
5ribosomal small subunit biogenesis (GO:0042274)6.06024275
6viral transcription (GO:0019083)5.14383864
7chaperone-mediated protein transport (GO:0072321)4.92445844
8translational termination (GO:0006415)4.86520312
9establishment of protein localization to mitochondrial membrane (GO:0090151)4.86343202
10SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.65265869
11protein neddylation (GO:0045116)4.62695955
12cotranslational protein targeting to membrane (GO:0006613)4.59939134
13protein targeting to ER (GO:0045047)4.56440658
14protein localization to endoplasmic reticulum (GO:0070972)4.36003587
15establishment of protein localization to endoplasmic reticulum (GO:0072599)4.32495805
16regulation of mitochondrial translation (GO:0070129)4.08631216
17translational elongation (GO:0006414)4.07490083
18negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.93240707
19viral life cycle (GO:0019058)3.87258302
20aminoglycoside antibiotic metabolic process (GO:0030647)3.85996429
21tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.85746198
22RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.85746198
23interferon-gamma production (GO:0032609)3.84885849
24maturation of SSU-rRNA (GO:0030490)3.79511592
25positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.69121974
26regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.65087687
27antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.64933660
28regulation of cellular amino acid metabolic process (GO:0006521)3.60454172
29nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.57783148
30cellular protein complex disassembly (GO:0043624)3.57435037
31negative regulation of ligase activity (GO:0051352)3.50066415
32negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.50066415
33DNA deamination (GO:0045006)3.47665722
34rRNA modification (GO:0000154)3.45082230
35peptidyl-histidine modification (GO:0018202)3.44196954
36ribosomal large subunit biogenesis (GO:0042273)3.42101629
37protein targeting to mitochondrion (GO:0006626)3.38324796
38rRNA methylation (GO:0031167)3.36493137
39translational initiation (GO:0006413)3.34838529
40anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.34296642
41platelet dense granule organization (GO:0060155)3.31240866
42ribonucleoprotein complex biogenesis (GO:0022613)3.31000328
43translation (GO:0006412)3.26703780
44proteasome assembly (GO:0043248)3.25731141
45positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.21394251
46chromatin remodeling at centromere (GO:0031055)3.19669555
47CENP-A containing nucleosome assembly (GO:0034080)3.18587870
48establishment of protein localization to mitochondrion (GO:0072655)3.16115728
49intracellular protein transmembrane import (GO:0044743)3.15623867
50signal transduction involved in cell cycle checkpoint (GO:0072395)3.15476971
51quinone metabolic process (GO:1901661)3.14198880
52DNA double-strand break processing (GO:0000729)3.13379361
53DNA catabolic process, exonucleolytic (GO:0000738)3.12975663
54response to interferon-beta (GO:0035456)3.12724055
55protein localization to mitochondrion (GO:0070585)3.12024171
56mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.11127320
57oxidative phosphorylation (GO:0006119)3.09598514
58immunoglobulin mediated immune response (GO:0016064)3.09572654
59positive regulation of ligase activity (GO:0051351)3.09457655
60ATP biosynthetic process (GO:0006754)3.08363732
61pseudouridine synthesis (GO:0001522)3.04733430
62hydrogen ion transmembrane transport (GO:1902600)3.04120708
63regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.03921858
64cellular component biogenesis (GO:0044085)3.03019643
65deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.00709774
66ATP synthesis coupled proton transport (GO:0015986)3.00348431
67energy coupled proton transport, down electrochemical gradient (GO:0015985)3.00348431
68deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.98421731
69neutrophil activation involved in immune response (GO:0002283)2.98347102
70mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.98303658
71mitochondrial respiratory chain complex I assembly (GO:0032981)2.98303658
72NADH dehydrogenase complex assembly (GO:0010257)2.98303658
73protein-cofactor linkage (GO:0018065)2.97642548
74protein complex disassembly (GO:0043241)2.97098026
75regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.96620995
76protein targeting to membrane (GO:0006612)2.96128705
77purine nucleoside triphosphate biosynthetic process (GO:0009145)2.95841017
78respiratory chain complex IV assembly (GO:0008535)2.95647401
79rRNA transcription (GO:0009303)2.94481359
80inner mitochondrial membrane organization (GO:0007007)2.89343017
81cullin deneddylation (GO:0010388)2.89072096
82purine ribonucleoside triphosphate biosynthetic process (GO:0009206)2.87185056
83formation of translation preinitiation complex (GO:0001731)2.86409647
84water-soluble vitamin biosynthetic process (GO:0042364)2.85750551
85histone mRNA metabolic process (GO:0008334)2.84577761
86protein deneddylation (GO:0000338)2.83760860
87base-excision repair, AP site formation (GO:0006285)2.83151130
88mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.82678147
89proton transport (GO:0015992)2.82188470
90electron transport chain (GO:0022900)2.82151844
91maturation of 5.8S rRNA (GO:0000460)2.82005214
92respiratory electron transport chain (GO:0022904)2.81417287
93GPI anchor biosynthetic process (GO:0006506)2.81125985
94regulation of mitotic spindle checkpoint (GO:1903504)2.81045706
95regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.81045706
96tRNA processing (GO:0008033)2.80977995
97mitochondrial transport (GO:0006839)2.79946882
98spliceosomal snRNP assembly (GO:0000387)2.79664753
99macromolecular complex disassembly (GO:0032984)2.77363980
100regulation of ubiquitin-protein transferase activity (GO:0051438)2.76838206
101replication fork processing (GO:0031297)2.75944346
102hydrogen transport (GO:0006818)2.75446684
103pyrimidine deoxyribonucleotide catabolic process (GO:0009223)2.74101815
104rRNA metabolic process (GO:0016072)2.72715005
105DNA damage response, signal transduction by p53 class mediator (GO:0030330)2.72531291
106antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.71291416
107cytochrome complex assembly (GO:0017004)2.71104088
108protein complex biogenesis (GO:0070271)2.70133901
109signal peptide processing (GO:0006465)2.68082223
110antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.68025953
111negative regulation of epidermis development (GO:0045683)2.63189502
112positive regulation of defense response to virus by host (GO:0002230)2.62782929
113regulation of mammary gland epithelial cell proliferation (GO:0033599)2.62342606
114cofactor catabolic process (GO:0051187)2.61993851
115DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.61417205
116nuclear-transcribed mRNA catabolic process (GO:0000956)2.59403099
117B cell mediated immunity (GO:0019724)2.58692045
118intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.57207486
119signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.57207486
120transcription elongation from RNA polymerase III promoter (GO:0006385)2.56818045
121termination of RNA polymerase III transcription (GO:0006386)2.56818045
122mitochondrial respiratory chain complex assembly (GO:0033108)2.54793386
123cellular response to interferon-beta (GO:0035458)2.54585739
124signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.52091879
125signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.52091879
126signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.52091879
127reactive oxygen species biosynthetic process (GO:1903409)2.51644309
128somite rostral/caudal axis specification (GO:0032525)2.51177684
129hydrogen peroxide biosynthetic process (GO:0050665)2.50640120
130GDP-mannose metabolic process (GO:0019673)2.50030062
131mRNA catabolic process (GO:0006402)2.49617553
132cytidine deamination (GO:0009972)2.47959378
133cytidine metabolic process (GO:0046087)2.47959378
134cytidine catabolic process (GO:0006216)2.47959378
135DNA damage response, detection of DNA damage (GO:0042769)2.44796873
136regulation of apoptotic process involved in morphogenesis (GO:1902337)2.43405157
137exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.43199726
138DNA replication checkpoint (GO:0000076)2.42227332
139respiratory burst (GO:0045730)2.41824596
140positive regulation of isotype switching (GO:0045830)2.41437770
141coenzyme catabolic process (GO:0009109)2.40704906
142nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.40651033
143pteridine-containing compound biosynthetic process (GO:0042559)2.40269616
144regulation of nuclear cell cycle DNA replication (GO:0033262)2.39709027
145aerobic respiration (GO:0009060)2.39611509
146negative regulation of epidermal cell differentiation (GO:0045605)2.39546358
147rRNA processing (GO:0006364)2.38966827
148signal transduction involved in DNA integrity checkpoint (GO:0072401)2.37808612
149signal transduction involved in DNA damage checkpoint (GO:0072422)2.37808612
150response to peptidoglycan (GO:0032494)2.36204124
151L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.33873513
152phenylpropanoid metabolic process (GO:0009698)2.32922998

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human6.69703728
2NOTCH1_17114293_ChIP-ChIP_T-ALL_Human4.17028666
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.61042884
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.59596435
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.30944506
6IRF8_22096565_ChIP-ChIP_GC-B_Human2.99726087
7EST1_17652178_ChIP-ChIP_JURKAT_Human2.95701573
8E2F7_22180533_ChIP-Seq_HELA_Human2.91616633
9MYC_18555785_ChIP-Seq_MESCs_Mouse2.84792958
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.84257267
11JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.62430590
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.57415757
13EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.55129224
14MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.54618348
15CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.51773921
16ELF1_17652178_ChIP-ChIP_JURKAT_Human2.44478409
17IRF8_21731497_ChIP-ChIP_J774_Mouse2.44233323
18KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.34947248
19KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.34947248
20KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.34947248
21SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse2.27267638
22FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse2.22631924
23ETS1_20019798_ChIP-Seq_JURKAT_Human2.21021109
24MYC_18358816_ChIP-ChIP_MESCs_Mouse2.11304015
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.03793431
26VDR_23849224_ChIP-Seq_CD4+_Human2.03580666
27SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.96860619
28FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.93406755
29SRF_21415370_ChIP-Seq_HL-1_Mouse1.90793181
30MYC_19030024_ChIP-ChIP_MESCs_Mouse1.88438576
31ELK1_19687146_ChIP-ChIP_HELA_Human1.87089221
32VDR_22108803_ChIP-Seq_LS180_Human1.84998027
33ZNF274_21170338_ChIP-Seq_K562_Hela1.84333596
34FLI1_27457419_Chip-Seq_LIVER_Mouse1.84303474
35FOXP3_21729870_ChIP-Seq_TREG_Human1.82992090
36E2F4_17652178_ChIP-ChIP_JURKAT_Human1.80824879
37E2F1_18555785_ChIP-Seq_MESCs_Mouse1.79999418
38PADI4_21655091_ChIP-ChIP_MCF-7_Human1.78833409
39CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.75103631
40HOXB4_20404135_ChIP-ChIP_EML_Mouse1.73523862
41* SPI1_23547873_ChIP-Seq_NB4_Human1.73105403
42MYC_19079543_ChIP-ChIP_MESCs_Mouse1.71111950
43EWS_26573619_Chip-Seq_HEK293_Human1.69334255
44DCP1A_22483619_ChIP-Seq_HELA_Human1.68133812
45IRF1_19129219_ChIP-ChIP_H3396_Human1.67971624
46NOTCH1_21737748_ChIP-Seq_TLL_Human1.67941532
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.67524251
48HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.67029591
49STAT4_19710469_ChIP-ChIP_TH1__Mouse1.65832149
50PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.64636746
51CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.64495184
52TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.63830351
53ERG_20887958_ChIP-Seq_HPC-7_Mouse1.63706136
54MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.55592624
55FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.50891585
56SCL_19346495_ChIP-Seq_HPC-7_Human1.47683478
57FUS_26573619_Chip-Seq_HEK293_Human1.47218148
58* XRN2_22483619_ChIP-Seq_HELA_Human1.43344225
59IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.42580935
60E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.40923337
61RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.40267610
62FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.38471490
63* ELK1_22589737_ChIP-Seq_MCF10A_Human1.38078292
64PCGF2_27294783_Chip-Seq_ESCs_Mouse1.37905212
65YY1_21170310_ChIP-Seq_MESCs_Mouse1.37159839
66IGF1R_20145208_ChIP-Seq_DFB_Human1.35892863
67* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.35680000
68TTF2_22483619_ChIP-Seq_HELA_Human1.34278755
69HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.33983543
70CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.32520928
71EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.31343548
72MYB_21317192_ChIP-Seq_ERMYB_Mouse1.30561620
73PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.27143239
74SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.25722291
75GABP_19822575_ChIP-Seq_HepG2_Human1.25446177
76EGR1_23403033_ChIP-Seq_LIVER_Mouse1.24794947
77YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.24351564
78IRF8_27001747_Chip-Seq_BMDM_Mouse1.24179944
79TP53_22573176_ChIP-Seq_HFKS_Human1.22872427
80TAF15_26573619_Chip-Seq_HEK293_Human1.22417508
81SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.22318180
82ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.14777874
83NELFA_20434984_ChIP-Seq_ESCs_Mouse1.13995290
84POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.13453427
85HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.13121654
86MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.13091434
87TP63_19390658_ChIP-ChIP_HaCaT_Human1.12915554
88P300_19829295_ChIP-Seq_ESCs_Human1.10993843
89NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10721549
90ZFP57_27257070_Chip-Seq_ESCs_Mouse1.10705201
91CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.10637362
92RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.09261699
93RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.07818804
94STAT3_1855785_ChIP-Seq_MESCs_Mouse1.06805071
95MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.05774862
96ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.05072848
97NANOG_19829295_ChIP-Seq_ESCs_Human1.04757877
98SOX2_19829295_ChIP-Seq_ESCs_Human1.04757877
99MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.02456583
100FOXA1_27270436_Chip-Seq_PROSTATE_Human1.02096707
101FOXA1_25329375_ChIP-Seq_VCAP_Human1.02096707
102NFE2_27457419_Chip-Seq_LIVER_Mouse1.01821674
103SUZ12_27294783_Chip-Seq_NPCs_Mouse1.01690994
104BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.01396435
105AR_20517297_ChIP-Seq_VCAP_Human1.00894796
106EZH2_27294783_Chip-Seq_NPCs_Mouse1.00685385
107CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.00516935
108GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.00453006
109LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.99082873
110POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.97667151
111NANOG_18555785_ChIP-Seq_MESCs_Mouse0.97326622
112GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96138323
113GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.95494715
114RUNX1_22412390_ChIP-Seq_EML_Mouse0.94842509
115SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.93650253
116PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.92938280
117POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.91474699
118MYB_26560356_Chip-Seq_TH2_Human0.91062213
119HTT_18923047_ChIP-ChIP_STHdh_Human0.90828853
120FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.90129647
121GATA3_26560356_Chip-Seq_TH2_Human0.89861014
122ER_23166858_ChIP-Seq_MCF-7_Human0.89774164
123TCF3_18692474_ChIP-Seq_MEFs_Mouse0.89423735
124E2F1_21310950_ChIP-Seq_MCF-7_Human0.88822161
125CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.88741346
126MYCN_18555785_ChIP-Seq_MESCs_Mouse0.88582917
127CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.88254369
128LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.88129551
129NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.87790498
130CTBP1_25329375_ChIP-Seq_LNCAP_Human0.87256567
131MYC_18940864_ChIP-ChIP_HL60_Human0.87095184
132* FOXA1_21572438_ChIP-Seq_LNCaP_Human0.86809987
133PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.86651789
134CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.85972657
135POU5F1_16153702_ChIP-ChIP_HESCs_Human0.85906366
136THAP11_20581084_ChIP-Seq_MESCs_Mouse0.85844148
137NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.85473439
138MYB_26560356_Chip-Seq_TH1_Human0.85279264
139ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.84830861
140KDM5A_27292631_Chip-Seq_BREAST_Human0.84684645
141PCGF2_27294783_Chip-Seq_NPCs_Mouse0.84467825
142CRX_20693478_ChIP-Seq_RETINA_Mouse0.84152535

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.63289224
2MP0009379_abnormal_foot_pigmentation3.21510956
3MP0005075_abnormal_melanosome_morpholog3.10410379
4MP0002148_abnormal_hypersensitivity_rea3.09236381
5MP0009785_altered_susceptibility_to3.07715123
6MP0005671_abnormal_response_to3.05363517
7MP0003436_decreased_susceptibility_to2.99815783
8MP0008058_abnormal_DNA_repair2.85891446
9MP0003011_delayed_dark_adaptation2.76717477
10MP0006082_CNS_inflammation2.73137825
11MP0003186_abnormal_redox_activity2.65518141
12MP0003724_increased_susceptibility_to2.61498427
13MP0006072_abnormal_retinal_apoptosis2.54188145
14MP0005000_abnormal_immune_tolerance2.49612141
15MP0006292_abnormal_olfactory_placode2.41548289
16MP0004381_abnormal_hair_follicle2.40756215
17MP0002837_dystrophic_cardiac_calcinosis2.37057912
18MP0005025_abnormal_response_to2.35531203
19MP0000685_abnormal_immune_system2.25048915
20MP0002254_reproductive_system_inflammat2.17727955
21MP0008877_abnormal_DNA_methylation2.12435263
22MP0002132_abnormal_respiratory_system2.07535993
23MP0002277_abnormal_respiratory_mucosa2.07507047
24MP0000372_irregular_coat_pigmentation2.06515693
25MP0010094_abnormal_chromosome_stability2.01042960
26MP0002102_abnormal_ear_morphology1.95990595
27MP0001790_abnormal_immune_system1.91287068
28MP0005387_immune_system_phenotype1.91287068
29MP0001800_abnormal_humoral_immune1.89596072
30MP0002723_abnormal_immune_serum1.87033988
31MP0002396_abnormal_hematopoietic_system1.79971409
32MP0002419_abnormal_innate_immunity1.79794917
33MP0003763_abnormal_thymus_physiology1.77994007
34MP0002420_abnormal_adaptive_immunity1.77168404
35MP0002452_abnormal_antigen_presenting1.75973643
36MP0001819_abnormal_immune_cell1.75383929
37MP0009333_abnormal_splenocyte_physiolog1.74309367
38MP0005084_abnormal_gallbladder_morpholo1.73367935
39MP0006035_abnormal_mitochondrial_morpho1.70230992
40MP0002405_respiratory_system_inflammati1.68572865
41MP0003806_abnormal_nucleotide_metabolis1.66754944
42MP0001853_heart_inflammation1.65653596
43MP0004147_increased_porphyrin_level1.64039434
44MP0002163_abnormal_gland_morphology1.64004714
45MP0005253_abnormal_eye_physiology1.63292588
46MP0004957_abnormal_blastocyst_morpholog1.59348367
47MP0008872_abnormal_physiological_respon1.55202859
48MP0008057_abnormal_DNA_replication1.53583204
49MP0004142_abnormal_muscle_tone1.51770149
50MP0006036_abnormal_mitochondrial_physio1.51326928
51MP0000490_abnormal_crypts_of1.45557773
52MP0002095_abnormal_skin_pigmentation1.45206154
53MP0000716_abnormal_immune_system1.43329506
54MP0002398_abnormal_bone_marrow1.42855528
55MP0001529_abnormal_vocalization1.41170653
56MP0010155_abnormal_intestine_physiology1.38045340
57MP0005551_abnormal_eye_electrophysiolog1.37164505
58MP0000858_altered_metastatic_potential1.36862444
59MP0003136_yellow_coat_color1.36398082
60MP0008995_early_reproductive_senescence1.34649312
61MP0000343_altered_response_to1.33852074
62MP0005389_reproductive_system_phenotype1.33284126
63MP0000689_abnormal_spleen_morphology1.32620008
64MP0008469_abnormal_protein_level1.32610499
65MP0001919_abnormal_reproductive_system1.30802675
66MP0002722_abnormal_immune_system1.28494163
67MP0002429_abnormal_blood_cell1.27965489
68MP0002876_abnormal_thyroid_physiology1.27139672
69MP0001845_abnormal_inflammatory_respons1.26468572
70MP0003111_abnormal_nucleus_morphology1.25029890
71MP0008789_abnormal_olfactory_epithelium1.23682866
72MP0000569_abnormal_digit_pigmentation1.23477693
73MP0004264_abnormal_extraembryonic_tissu1.23102597
74MP0002160_abnormal_reproductive_system1.22984788
75MP0002090_abnormal_vision1.21087598
76MP0009764_decreased_sensitivity_to1.19221340
77MP0002006_tumorigenesis1.17646667
78MP0004782_abnormal_surfactant_physiolog1.16539844
79MP0002332_abnormal_exercise_endurance1.16062736
80MP0003646_muscle_fatigue1.15340622
81MP0005408_hypopigmentation1.12662464
82MP0003787_abnormal_imprinting1.10966798
83MP0005310_abnormal_salivary_gland1.09769211
84MP0005645_abnormal_hypothalamus_physiol1.09061658
85MP0005464_abnormal_platelet_physiology1.08801597
86MP0001293_anophthalmia1.07977831
87MP0005332_abnormal_amino_acid1.05224016
88MP0001905_abnormal_dopamine_level1.04692768
89MP0001533_abnormal_skeleton_physiology1.04068914
90MP0002138_abnormal_hepatobiliary_system1.03050717
91MP0003656_abnormal_erythrocyte_physiolo1.01405401
92MP0002166_altered_tumor_susceptibility1.00278552
93MP0001348_abnormal_lacrimal_gland0.99893833
94MP0003448_altered_tumor_morphology0.99807925
95MP0004145_abnormal_muscle_electrophysio0.97731925
96MP0002210_abnormal_sex_determination0.97317822
97MP0003121_genomic_imprinting0.96257961
98MP0000631_abnormal_neuroendocrine_gland0.95404703
99MP0004215_abnormal_myocardial_fiber0.94913491
100MP0008932_abnormal_embryonic_tissue0.94150472
101MP0009697_abnormal_copulation0.93876085
102MP0005646_abnormal_pituitary_gland0.93693283
103MP0003786_premature_aging0.93619862
104MP0002234_abnormal_pharynx_morphology0.93145985
105MP0005379_endocrine/exocrine_gland_phen0.93104196
106MP0002938_white_spotting0.91038804
107MP0005410_abnormal_fertilization0.90014965
108MP0005394_taste/olfaction_phenotype0.89946539
109MP0005499_abnormal_olfactory_system0.89946539
110MP0002736_abnormal_nociception_after0.89864964
111MP0002638_abnormal_pupillary_reflex0.88849621
112MP0005451_abnormal_body_composition0.87926357
113MP0003567_abnormal_fetal_cardiomyocyte0.86919028
114MP0001929_abnormal_gametogenesis0.85467380
115MP0000516_abnormal_urinary_system0.85318367
116MP0005367_renal/urinary_system_phenotyp0.85318367
117MP0003693_abnormal_embryo_hatching0.84934636
118MP0001986_abnormal_taste_sensitivity0.84702812
119MP0005319_abnormal_enzyme/_coenzyme0.84398382
120MP0000653_abnormal_sex_gland0.83421377
121MP0000427_abnormal_hair_cycle0.82768799
122MP0005174_abnormal_tail_pigmentation0.82331530
123MP0005397_hematopoietic_system_phenotyp0.82260235
124MP0001545_abnormal_hematopoietic_system0.82260235
125MP0008007_abnormal_cellular_replicative0.81973654
126MP0000015_abnormal_ear_pigmentation0.80642836
127MP0003195_calcinosis0.80139768
128MP0001145_abnormal_male_reproductive0.79686409
129MP0009763_increased_sensitivity_to0.78882070
130MP0008873_increased_physiological_sensi0.77993152
131MP0002019_abnormal_tumor_incidence0.77909840
132MP0000703_abnormal_thymus_morphology0.77603251
133MP0002009_preneoplasia0.77007654
134MP0003077_abnormal_cell_cycle0.76968173
135MP0001119_abnormal_female_reproductive0.76806676
136MP0000358_abnormal_cell_content/0.76771510
137MP0003828_pulmonary_edema0.76272534
138MP0001485_abnormal_pinna_reflex0.76010964
139MP0002693_abnormal_pancreas_physiology0.76001609
140MP0004947_skin_inflammation0.75858904
141MP0001873_stomach_inflammation0.75758983
142MP0005636_abnormal_mineral_homeostasis0.75252956
143MP0003252_abnormal_bile_duct0.75164787
144MP0003137_abnormal_impulse_conducting0.74116142
145MP0005584_abnormal_enzyme/coenzyme_acti0.72570005
146MP0008875_abnormal_xenobiotic_pharmacok0.72541700
147MP0001727_abnormal_embryo_implantation0.72197594
148MP0005164_abnormal_response_to0.71624261
149MP0005266_abnormal_metabolism0.71424535
150MP0005257_abnormal_intraocular_pressure0.70880514
151MP0001984_abnormal_olfaction0.70738406
152MP0000313_abnormal_cell_death0.68805893
153MP0005376_homeostasis/metabolism_phenot0.68301875
154MP0005390_skeleton_phenotype0.68046983
155MP0001324_abnormal_eye_pigmentation0.67403934
156MP0001764_abnormal_homeostasis0.64998676
157MP0000678_abnormal_parathyroid_gland0.63941863
158MP0003718_maternal_effect0.62464809
159MP0003866_abnormal_defecation0.62459633
160MP0004043_abnormal_pH_regulation0.62271026

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of cells of the erythroid lineage (HP:0012130)4.43612943
2Abnormal number of erythroid precursors (HP:0012131)4.32614538
33-Methylglutaconic aciduria (HP:0003535)4.21147746
4Elevated erythrocyte sedimentation rate (HP:0003565)3.86869142
5Reduced antithrombin III activity (HP:0001976)3.83923528
6Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)3.80648474
7Acute necrotizing encephalopathy (HP:0006965)3.71468488
8Multiple enchondromatosis (HP:0005701)3.67919665
9Type I transferrin isoform profile (HP:0003642)3.59791656
10Mitochondrial inheritance (HP:0001427)3.51627483
11Renal Fanconi syndrome (HP:0001994)3.46646461
12Reticulocytopenia (HP:0001896)3.45783359
13Increased hepatocellular lipid droplets (HP:0006565)3.35292622
14Hepatocellular necrosis (HP:0001404)3.31207727
15Abnormal mitochondria in muscle tissue (HP:0008316)3.30936536
16Acute encephalopathy (HP:0006846)3.27764248
17Aplastic anemia (HP:0001915)3.24157773
18Hepatic necrosis (HP:0002605)3.20964185
19Lipid accumulation in hepatocytes (HP:0006561)3.13425068
20Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.13236472
21Increased CSF lactate (HP:0002490)3.12168145
22Poor head control (HP:0002421)3.08426415
23Increased IgM level (HP:0003496)3.08330059
24Pallor (HP:0000980)3.03240841
25Methylmalonic acidemia (HP:0002912)3.02639204
26Myositis (HP:0100614)3.00774667
27Recurrent abscess formation (HP:0002722)2.98009410
28Exertional dyspnea (HP:0002875)2.96767045
29Partial duplication of thumb phalanx (HP:0009944)2.95034842
30Petechiae (HP:0000967)2.92428438
31Decreased activity of mitochondrial respiratory chain (HP:0008972)2.89513694
32Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.89513694
33Aplasia/Hypoplasia of the sacrum (HP:0008517)2.85544910
34Progressive macrocephaly (HP:0004481)2.83727882
35Abnormality of glycolysis (HP:0004366)2.81510998
36Increased serum pyruvate (HP:0003542)2.81510998
37Recurrent bacterial skin infections (HP:0005406)2.72834382
38Pancreatic cysts (HP:0001737)2.70745276
39Macrocytic anemia (HP:0001972)2.69448914
40Renal cortical cysts (HP:0000803)2.67328544
41Orchitis (HP:0100796)2.67246871
42Abnormality of midbrain morphology (HP:0002418)2.66824344
43Molar tooth sign on MRI (HP:0002419)2.66824344
44Microvesicular hepatic steatosis (HP:0001414)2.64880380
45Methylmalonic aciduria (HP:0012120)2.64407425
46Congenital, generalized hypertrichosis (HP:0004540)2.62461390
47Optic disc pallor (HP:0000543)2.61590253
48Increased serum lactate (HP:0002151)2.60846554
49Abnormal hemoglobin (HP:0011902)2.59996481
50Increased intramyocellular lipid droplets (HP:0012240)2.59825547
51Bilateral microphthalmos (HP:0007633)2.59736691
52Lethargy (HP:0001254)2.48150197
53Pancreatic fibrosis (HP:0100732)2.46670695
54Partial duplication of the phalanx of hand (HP:0009999)2.45011017
55Abnormal protein glycosylation (HP:0012346)2.44125322
56Abnormal glycosylation (HP:0012345)2.44125322
57Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.44125322
58Abnormal protein N-linked glycosylation (HP:0012347)2.44125322
59Respiratory difficulties (HP:0002880)2.39428698
60Combined immunodeficiency (HP:0005387)2.39394795
61Increased muscle lipid content (HP:0009058)2.38856681
62Cerebral edema (HP:0002181)2.38233757
63Abnormality of alanine metabolism (HP:0010916)2.35282041
64Hyperalaninemia (HP:0003348)2.35282041
65Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.35282041
66Hypoproteinemia (HP:0003075)2.34559999
67Exercise intolerance (HP:0003546)2.33219395
68Nasolacrimal duct obstruction (HP:0000579)2.32810449
69Medial flaring of the eyebrow (HP:0010747)2.28364862
70Eczematoid dermatitis (HP:0000976)2.28258832
71True hermaphroditism (HP:0010459)2.27949478
72CNS demyelination (HP:0007305)2.25548908
73Purpura (HP:0000979)2.24671219
74Abnormality of the renal cortex (HP:0011035)2.22909500
75Thrombocytosis (HP:0001894)2.22578126
76Abnormality of renal resorption (HP:0011038)2.20316719
77Abnormality of the heme biosynthetic pathway (HP:0010472)2.17874413
78Rib fusion (HP:0000902)2.17693031
79Sparse eyelashes (HP:0000653)2.15592098
80IgM deficiency (HP:0002850)2.15547658
81Generalized aminoaciduria (HP:0002909)2.14611669
82Microretrognathia (HP:0000308)2.11546871
83Hypothermia (HP:0002045)2.11112836
84Vacuolated lymphocytes (HP:0001922)2.09545351
85Abnormality of methionine metabolism (HP:0010901)2.07790904
86Abnormal pupillary function (HP:0007686)2.07347963
87Severe combined immunodeficiency (HP:0004430)2.05960089
88Nephronophthisis (HP:0000090)2.04977601
89Abnormality of the anterior horn cell (HP:0006802)2.04612388
90Degeneration of anterior horn cells (HP:0002398)2.04612388
91Hyperglycinemia (HP:0002154)2.03754291
92Hypochromic anemia (HP:0001931)2.03687827
93Microcytic anemia (HP:0001935)2.02734156
94Parakeratosis (HP:0001036)2.02687704
95Ragged-red muscle fibers (HP:0003200)2.01902876
96Recurrent skin infections (HP:0001581)2.01296697
97IgG deficiency (HP:0004315)2.01102713
98Congenital stationary night blindness (HP:0007642)2.01091433
99Colon cancer (HP:0003003)1.99510685
100Respiratory failure (HP:0002878)1.98829851
101Lactic acidosis (HP:0003128)1.98228981
102Abnormality of macrophages (HP:0004311)1.97395195
103Abnormality of aspartate family amino acid metabolism (HP:0010899)1.96946892
104Abnormality of T cell physiology (HP:0011840)1.96701467
105Hypochromic microcytic anemia (HP:0004840)1.96440630
106Leukodystrophy (HP:0002415)1.94781564
107Vasculitis (HP:0002633)1.94617560
108Abnormal lung lobation (HP:0002101)1.93693298
109Abnormality of aromatic amino acid family metabolism (HP:0004338)1.93628767
110Increased serum ferritin (HP:0003281)1.93256012
111Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.92534197
112Absent thumb (HP:0009777)1.92424640
113Hypoplasia of the fovea (HP:0007750)1.90248936
114Aplasia/Hypoplasia of the fovea (HP:0008060)1.90248936
115Optic neuritis (HP:0100653)1.90191697
116Retrobulbar optic neuritis (HP:0100654)1.90191697
117Dicarboxylic aciduria (HP:0003215)1.89634892
118Abnormality of dicarboxylic acid metabolism (HP:0010995)1.89634892
119X-linked dominant inheritance (HP:0001423)1.89455379
120Palpitations (HP:0001962)1.88533331
121Recurrent gram-negative bacterial infections (HP:0005420)1.88499667
122Anomalous pulmonary venous return (HP:0010772)1.86913749
123Abnormality of serum amino acid levels (HP:0003112)1.86175852
124Cleft eyelid (HP:0000625)1.85807281
125Rectal fistula (HP:0100590)1.84726175
126Rectovaginal fistula (HP:0000143)1.84726175
127Meckel diverticulum (HP:0002245)1.82868994
128Autoimmune hemolytic anemia (HP:0001890)1.80739683
129Abnormality of the ileum (HP:0001549)1.80508408
130Thyroiditis (HP:0100646)1.79987317
131Hypergammaglobulinemia (HP:0010702)1.79976559
132Aplasia/Hypoplasia of the uvula (HP:0010293)1.79572025
133Oral leukoplakia (HP:0002745)1.79067377
134Abnormality of T cells (HP:0002843)1.78054410
135Aplasia/hypoplasia of the uterus (HP:0008684)1.78045481
136Abnormality of vitamin B metabolism (HP:0004340)1.77806569
137Abnormality of T cell number (HP:0011839)1.76350866
138Pancytopenia (HP:0001876)1.75828690
139Hyperphosphaturia (HP:0003109)1.75682048
140Type 2 muscle fiber atrophy (HP:0003554)1.75426340
141Congenital ichthyosiform erythroderma (HP:0007431)1.74992010
142Trismus (HP:0000211)1.74763256
143Abnormal rod and cone electroretinograms (HP:0008323)1.74672919
144Abnormality of chromosome stability (HP:0003220)1.74596056
145Glycosuria (HP:0003076)1.72778545
146Abnormality of urine glucose concentration (HP:0011016)1.72778545
147Gingival bleeding (HP:0000225)1.70647146
148Sclerocornea (HP:0000647)1.70305289
149Emotional lability (HP:0000712)1.69262116
150Abnormality of the renal medulla (HP:0100957)1.68268180
151Abnormality of the vitamin B12 metabolism (HP:0004341)1.67789182
152Abnormality of the preputium (HP:0100587)1.67598442
153Hypoglycemic coma (HP:0001325)1.63762405
154Decreased electroretinogram (ERG) amplitude (HP:0000654)1.63760802
155Congenital primary aphakia (HP:0007707)1.60997133
156Abnormality of the fovea (HP:0000493)1.60907458

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME23.58443243
2VRK23.47048963
3ADRBK22.92108762
4PBK2.81814465
5GRK52.78522773
6MAP4K22.73225767
7GRK72.69249996
8MST42.68545238
9FRK2.64743624
10PIM22.54514327
11NUAK12.51405518
12GRK62.49221740
13ERN12.31128667
14TRIM282.21674596
15GRK12.15377838
16TXK2.05967460
17BLK2.04381971
18NEK12.00286762
19CSF1R1.98458906
20CDK121.98451875
21NME11.90401294
22ZAK1.89714045
23MAP3K141.87995344
24TGFBR21.86026464
25IKBKB1.80877028
26ACVR1B1.78825034
27IRAK41.77654909
28WNK31.72507830
29IRAK31.62268625
30STK161.60875563
31TBK11.52172182
32MOS1.48009970
33KIT1.47442009
34IKBKE1.46619899
35VRK11.45536029
36TESK21.44062152
37BCR1.44058536
38CDC71.39636019
39PLK31.37446299
40STK101.35778602
41TEC1.35541269
42TLK11.35436906
43MUSK1.34378940
44MATK1.34288159
45TYK21.29931047
46JAK31.28316938
47MAP4K11.22585685
48MKNK21.17433899
49ARAF1.14522608
50ZAP701.10147346
51BUB11.08270762
52WEE11.07639194
53KDR1.05813310
54PDK21.05615075
55ABL21.04862837
56PRKG21.02570873
57BMPR1B1.00574281
58CDK81.00186388
59EIF2AK20.99668601
60MAPKAPK50.98753952
61PINK10.98533239
62SYK0.98510932
63INSRR0.97902393
64OXSR10.96965251
65CSNK1G30.94990855
66BRSK20.94755826
67BCKDK0.94085041
68PLK40.92990792
69BTK0.92625337
70WNK40.90524729
71ERBB30.89724613
72NLK0.89543350
73MAPK70.88864781
74TAF10.88415744
75IRAK20.88215043
76PIM10.88146971
77CDK70.85291277
78CSNK1G20.84170517
79MAP3K120.81567179
80CSNK1G10.80939027
81EIF2AK10.78147349
82ITK0.77115534
83MAPK130.76977568
84NEK90.76795915
85PLK20.76419467
86MAP3K40.75967636
87CDK190.75794058
88LCK0.72687645
89CSK0.72535768
90LRRK20.71805089
91MYLK0.71073411
92ATR0.70283953
93HIPK20.69470175
94CSNK1A1L0.69206273
95STK390.67963063
96LYN0.67552667
97BMPR20.67315381
98FLT30.67300762
99SRPK10.66779752
100DYRK30.65747067
101EIF2AK30.64552681
102CHUK0.64461457
103ADRBK10.63921317
104TAOK30.63699326
105MAP2K60.62155630
106DYRK20.61339989
107PRKCD0.60744884
108MKNK10.59589739
109CCNB10.57422542
110PIK3CG0.57273280
111CSNK2A20.55682845
112OBSCN0.55591638
113STK30.55269124
114DAPK10.55201557
115TSSK60.54522475
116TTK0.52693837
117STK40.50782025
118IRAK10.50655167
119PASK0.50485939
120TNK20.49612118
121PHKG10.48390909
122PHKG20.48390909
123PAK40.48261737
124MAP2K70.48173208
125RPS6KB20.47409852
126TNIK0.47333721
127RPS6KA50.44316496
128ILK0.43752682
129CDK30.43622990
130PAK30.43487710
131CSNK2A10.42630258
132MAPK40.42364919
133LIMK10.42226220
134YES10.41709428
135PRKCQ0.41391663
136MAPKAPK20.40670845
137AURKB0.40209815
138MARK30.39923300
139PRKCE0.38461726
140RIPK40.37825975
141ATM0.36917575
142TESK10.36470629
143IGF1R0.36006687
144PLK10.35076173
145RPS6KA40.34710487
146AURKA0.34442793
147NEK20.33779921
148STK38L0.31613955

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030105.06110666
2Proteasome_Homo sapiens_hsa030502.96185854
3Oxidative phosphorylation_Homo sapiens_hsa001902.64249377
4Protein export_Homo sapiens_hsa030602.55733388
5RNA polymerase_Homo sapiens_hsa030202.55152905
6Cytosolic DNA-sensing pathway_Homo sapiens_hsa046232.48244930
7Parkinsons disease_Homo sapiens_hsa050122.35713800
8DNA replication_Homo sapiens_hsa030302.04096270
9Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.91962269
10Allograft rejection_Homo sapiens_hsa053301.76718821
11Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.76215791
12Graft-versus-host disease_Homo sapiens_hsa053321.68655737
13Pyrimidine metabolism_Homo sapiens_hsa002401.68636999
14Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.64878780
15Homologous recombination_Homo sapiens_hsa034401.60384628
16Vitamin B6 metabolism_Homo sapiens_hsa007501.57334265
17Alzheimers disease_Homo sapiens_hsa050101.56893297
18Arachidonic acid metabolism_Homo sapiens_hsa005901.56764559
19Folate biosynthesis_Homo sapiens_hsa007901.56747687
20Huntingtons disease_Homo sapiens_hsa050161.56675017
21Pentose and glucuronate interconversions_Homo sapiens_hsa000401.51595412
22Mismatch repair_Homo sapiens_hsa034301.51166958
23RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.44147017
24Intestinal immune network for IgA production_Homo sapiens_hsa046721.43428379
25Cardiac muscle contraction_Homo sapiens_hsa042601.41998731
26Primary immunodeficiency_Homo sapiens_hsa053401.36812444
27Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.32037571
28Nucleotide excision repair_Homo sapiens_hsa034201.27108655
29Basal transcription factors_Homo sapiens_hsa030221.22731906
30Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.22409038
31Linoleic acid metabolism_Homo sapiens_hsa005911.20010910
32Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.15680767
33Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.15115404
34Sulfur metabolism_Homo sapiens_hsa009201.14772633
35Leishmaniasis_Homo sapiens_hsa051401.14471359
36Other glycan degradation_Homo sapiens_hsa005111.13457984
37Chemical carcinogenesis_Homo sapiens_hsa052041.10872475
38RNA degradation_Homo sapiens_hsa030181.06328345
39Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.06244533
40Legionellosis_Homo sapiens_hsa051341.04769911
41Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.04767776
42NF-kappa B signaling pathway_Homo sapiens_hsa040641.03949410
43Asthma_Homo sapiens_hsa053101.01213411
44Collecting duct acid secretion_Homo sapiens_hsa049661.01052931
45Fatty acid elongation_Homo sapiens_hsa000620.99785191
46Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.99198009
47Steroid biosynthesis_Homo sapiens_hsa001000.98895278
48alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.97898830
49Autoimmune thyroid disease_Homo sapiens_hsa053200.97874301
50Hematopoietic cell lineage_Homo sapiens_hsa046400.96424512
51Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.96139642
52Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.93771422
53Herpes simplex infection_Homo sapiens_hsa051680.93306606
54Ether lipid metabolism_Homo sapiens_hsa005650.93088095
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.93008483
56Cysteine and methionine metabolism_Homo sapiens_hsa002700.92342022
57Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.91445098
58Galactose metabolism_Homo sapiens_hsa000520.90226716
59Spliceosome_Homo sapiens_hsa030400.90018544
60Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.89643893
61Base excision repair_Homo sapiens_hsa034100.87824020
62Maturity onset diabetes of the young_Homo sapiens_hsa049500.87395292
63Glutathione metabolism_Homo sapiens_hsa004800.87188994
64Phototransduction_Homo sapiens_hsa047440.86948590
65SNARE interactions in vesicular transport_Homo sapiens_hsa041300.86574436
66Non-homologous end-joining_Homo sapiens_hsa034500.85910815
67Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.85814404
68Measles_Homo sapiens_hsa051620.85597219
69Butanoate metabolism_Homo sapiens_hsa006500.83747285
70Malaria_Homo sapiens_hsa051440.79743937
71Peroxisome_Homo sapiens_hsa041460.79597804
72Nitrogen metabolism_Homo sapiens_hsa009100.78782275
73Antigen processing and presentation_Homo sapiens_hsa046120.78699133
74NOD-like receptor signaling pathway_Homo sapiens_hsa046210.78332183
75Selenocompound metabolism_Homo sapiens_hsa004500.77432800
76Pyruvate metabolism_Homo sapiens_hsa006200.76257606
77Sulfur relay system_Homo sapiens_hsa041220.75860915
78Pentose phosphate pathway_Homo sapiens_hsa000300.73734718
79Staphylococcus aureus infection_Homo sapiens_hsa051500.72698850
80Histidine metabolism_Homo sapiens_hsa003400.72009456
81Fanconi anemia pathway_Homo sapiens_hsa034600.70560924
82Fructose and mannose metabolism_Homo sapiens_hsa000510.70335986
83Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.70144614
84Retinol metabolism_Homo sapiens_hsa008300.69017715
85Rheumatoid arthritis_Homo sapiens_hsa053230.68995986
86Toll-like receptor signaling pathway_Homo sapiens_hsa046200.65673234
87Metabolic pathways_Homo sapiens_hsa011000.65652078
88Purine metabolism_Homo sapiens_hsa002300.65627159
89One carbon pool by folate_Homo sapiens_hsa006700.64190749
90Steroid hormone biosynthesis_Homo sapiens_hsa001400.63188827
91Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.60450941
92Drug metabolism - other enzymes_Homo sapiens_hsa009830.59932434
93Caffeine metabolism_Homo sapiens_hsa002320.58255971
94Pertussis_Homo sapiens_hsa051330.57400825
95Tryptophan metabolism_Homo sapiens_hsa003800.53660368
96Jak-STAT signaling pathway_Homo sapiens_hsa046300.53541431
97Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.50463977
98Apoptosis_Homo sapiens_hsa042100.49210110
99Cell cycle_Homo sapiens_hsa041100.48642225
100RNA transport_Homo sapiens_hsa030130.48321001
101Primary bile acid biosynthesis_Homo sapiens_hsa001200.45766966
102Complement and coagulation cascades_Homo sapiens_hsa046100.45431411
103Regulation of autophagy_Homo sapiens_hsa041400.45348253
104Influenza A_Homo sapiens_hsa051640.44309897
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.43314241
106Type I diabetes mellitus_Homo sapiens_hsa049400.42583391
107African trypanosomiasis_Homo sapiens_hsa051430.42335927
108Tyrosine metabolism_Homo sapiens_hsa003500.41502332
109Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.40581457
110Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.40576312
111Oocyte meiosis_Homo sapiens_hsa041140.40295776
112p53 signaling pathway_Homo sapiens_hsa041150.39720286
113Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.39339571
114N-Glycan biosynthesis_Homo sapiens_hsa005100.38009280
115Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.37187838
116Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.37154108
117Systemic lupus erythematosus_Homo sapiens_hsa053220.36302136
118Propanoate metabolism_Homo sapiens_hsa006400.35899334
119Epstein-Barr virus infection_Homo sapiens_hsa051690.35528360
120Fatty acid degradation_Homo sapiens_hsa000710.33047630
1212-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.31439279
122Olfactory transduction_Homo sapiens_hsa047400.30855645
123Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.30239928
124beta-Alanine metabolism_Homo sapiens_hsa004100.29838341
125Carbon metabolism_Homo sapiens_hsa012000.25074158

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