CMKLR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of integrin activation (GO:0033623)8.15781719
2proline biosynthetic process (GO:0006561)5.75867554
3negative regulation of granulocyte differentiation (GO:0030853)5.57473379
4embryonic process involved in female pregnancy (GO:0060136)5.31670031
5apoptotic cell clearance (GO:0043277)5.16775115
6neutrophil activation involved in immune response (GO:0002283)4.85935621
7response to peptidoglycan (GO:0032494)4.65099118
8cellular response to thyroid hormone stimulus (GO:0097067)4.49641366
9positive regulation of protein homooligomerization (GO:0032464)4.42772362
10embryonic placenta development (GO:0001892)4.37037556
11* negative regulation of interleukin-12 production (GO:0032695)4.30061611
12transcription from mitochondrial promoter (GO:0006390)4.25883345
13immunoglobulin mediated immune response (GO:0016064)4.21598209
14cellular response to zinc ion (GO:0071294)4.18793676
15positive regulation of gamma-delta T cell activation (GO:0046645)4.17483290
16glycosphingolipid catabolic process (GO:0046479)4.15214492
17proline metabolic process (GO:0006560)4.08834612
18low-density lipoprotein particle clearance (GO:0034383)4.07689998
19amino sugar catabolic process (GO:0046348)4.02138737
20positive regulation by symbiont of host defense response (GO:0052509)3.99605852
21modulation by symbiont of host defense response (GO:0052031)3.99605852
22modulation by organism of immune response of other organism involved in symbiotic interaction (GO:003.99605852
23modulation by organism of defense response of other organism involved in symbiotic interaction (GO:03.99605852
24positive regulation by organism of defense response of other organism involved in symbiotic interact3.99605852
25modulation by symbiont of host immune response (GO:0052553)3.99605852
26regulation of apoptotic cell clearance (GO:2000425)3.97529768
27complement activation, alternative pathway (GO:0006957)3.96577894
28T-helper 1 type immune response (GO:0042088)3.83614208
29establishment of apical/basal cell polarity (GO:0035089)3.81448693
30regulation of mast cell degranulation (GO:0043304)3.80167405
31N-acetylneuraminate metabolic process (GO:0006054)3.75063207
32positive regulation of mast cell activation (GO:0033005)3.74901677
33oligosaccharide catabolic process (GO:0009313)3.74086296
34glycolipid catabolic process (GO:0019377)3.72703543
35glial cell migration (GO:0008347)3.69093529
36negative regulation of stress fiber assembly (GO:0051497)3.65717109
37detection of molecule of bacterial origin (GO:0032490)3.64062877
38mannose metabolic process (GO:0006013)3.60838512
39regulation of protein homooligomerization (GO:0032462)3.58706048
40barbed-end actin filament capping (GO:0051016)3.56280989
41lipopolysaccharide-mediated signaling pathway (GO:0031663)3.53701144
42regulation of mast cell activation involved in immune response (GO:0033006)3.51496816
43replication fork processing (GO:0031297)3.50479651
44detection of other organism (GO:0098543)3.50375600
45regulation of cholesterol storage (GO:0010885)3.46679528
46detection of external biotic stimulus (GO:0098581)3.46092411
47antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.44774500
48response to thyroid hormone (GO:0097066)3.42344287
49* regulation of mononuclear cell migration (GO:0071675)3.41830966
50interferon-gamma-mediated signaling pathway (GO:0060333)3.41668090
51membrane invagination (GO:0010324)3.38006094
52macrophage activation involved in immune response (GO:0002281)3.37330464
53endothelial cell chemotaxis (GO:0035767)3.35286107
54regulation of leukocyte degranulation (GO:0043300)3.33208214
55lipoxygenase pathway (GO:0019372)3.33085009
56regulation of antigen processing and presentation (GO:0002577)3.32265914
57regulation of T cell tolerance induction (GO:0002664)3.31777063
58negative regulation of erythrocyte differentiation (GO:0045647)3.31009003
59cellular response to ATP (GO:0071318)3.30721701
60positive regulation of monocyte chemotaxis (GO:0090026)3.30575693
61regulation of myeloid leukocyte mediated immunity (GO:0002886)3.29527589
62positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.29310291
63positive regulation of cell adhesion mediated by integrin (GO:0033630)3.29298234
64ceramide catabolic process (GO:0046514)3.28435800
65regulation of dendritic cell antigen processing and presentation (GO:0002604)3.23939272
66positive regulation of cellular amide metabolic process (GO:0034250)3.20203883
67regulation of mast cell activation (GO:0033003)3.19460367
68regulation of interferon-beta biosynthetic process (GO:0045357)3.19049438
69negative regulation of tumor necrosis factor production (GO:0032720)3.16899242
70basement membrane organization (GO:0071711)3.16634753
71protein localization to endosome (GO:0036010)3.16588342
72oxidative demethylation (GO:0070989)3.16143302
73myeloid cell activation involved in immune response (GO:0002275)3.15946691
74detection of bacterium (GO:0016045)3.15664673
75apoptotic process involved in morphogenesis (GO:0060561)3.15033505
76establishment of monopolar cell polarity (GO:0061162)3.14111610
77establishment or maintenance of monopolar cell polarity (GO:0061339)3.14111610
78regulation of podosome assembly (GO:0071801)3.11324513
79cellular extravasation (GO:0045123)3.10012019
80phagocytosis, engulfment (GO:0006911)3.09672894
81granulocyte activation (GO:0036230)3.08827090
82regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.05826144
83myeloid dendritic cell differentiation (GO:0043011)3.05790550
84B cell mediated immunity (GO:0019724)3.05376059
85microglial cell activation (GO:0001774)3.05100894
86negative regulation of tumor necrosis factor superfamily cytokine production (GO:1903556)3.04577807
87antigen processing and presentation of endogenous peptide antigen (GO:0002483)3.03240741
88NIK/NF-kappaB signaling (GO:0038061)3.02738833
89anatomical structure regression (GO:0060033)3.02731042
90negative regulation of interleukin-6 production (GO:0032715)3.01703152
91detection of biotic stimulus (GO:0009595)3.00312427
92negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.00170268
93protein heterotrimerization (GO:0070208)3.00008463
94antigen processing and presentation of endogenous antigen (GO:0019883)2.95918213
95adenosine receptor signaling pathway (GO:0001973)2.95661922
96regulation of tolerance induction (GO:0002643)2.95085256
97negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.93876188
98positive regulation of protein oligomerization (GO:0032461)2.92487422
99positive regulation of type 2 immune response (GO:0002830)2.90488311
100regulation of tumor necrosis factor biosynthetic process (GO:0042534)2.90469879
101monocyte chemotaxis (GO:0002548)2.90296029
102antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.89996901
103macrophage differentiation (GO:0030225)2.88046996
104regulation of gamma-delta T cell activation (GO:0046643)2.87691780
105response to host immune response (GO:0052572)2.87636079
106response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.87636079
107regulation of monocyte chemotaxis (GO:0090025)2.87201432
108* regulation of macrophage chemotaxis (GO:0010758)2.87191182
109positive regulation of cholesterol efflux (GO:0010875)2.87042135
110response to laminar fluid shear stress (GO:0034616)2.86023239
111myeloid dendritic cell activation (GO:0001773)2.84919350
112negative regulation of cartilage development (GO:0061037)2.83727543
113negative regulation of cytokine production involved in immune response (GO:0002719)2.82557841
114hypotonic response (GO:0006971)2.82276811
115keratan sulfate catabolic process (GO:0042340)2.81805634
116neutrophil activation (GO:0042119)2.80648097
117positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.80126106
118face development (GO:0060324)2.79571116
119eosinophil chemotaxis (GO:0048245)2.78300108
120membrane lipid catabolic process (GO:0046466)2.77643199
121cellular response to interferon-gamma (GO:0071346)2.76823560
122lymphocyte chemotaxis (GO:0048247)2.76796055
123regulation of hypersensitivity (GO:0002883)2.76378800
124positive regulation of developmental pigmentation (GO:0048087)2.76150571
125production of molecular mediator involved in inflammatory response (GO:0002532)2.75525244
126dendritic cell differentiation (GO:0097028)2.74769411
127stress fiber assembly (GO:0043149)2.74590378
128respiratory burst (GO:0045730)2.74284798
129response to muramyl dipeptide (GO:0032495)2.70614035
130type I interferon signaling pathway (GO:0060337)2.70514903
131cellular response to type I interferon (GO:0071357)2.70514903
132positive regulation of receptor recycling (GO:0001921)2.69889194
133pinocytosis (GO:0006907)2.68288578
134response to type I interferon (GO:0034340)2.67176488
135negative regulation of interleukin-8 production (GO:0032717)2.66400386
136negative regulation of chondrocyte differentiation (GO:0032331)2.66319619
137negative regulation of myeloid cell apoptotic process (GO:0033033)2.66239977
138response to interferon-gamma (GO:0034341)2.66109034
139positive regulation of macrophage cytokine production (GO:0060907)2.65681730
140white fat cell differentiation (GO:0050872)2.65509885
141negative regulation of actin filament bundle assembly (GO:0032232)2.65043286
142embryonic camera-type eye development (GO:0031076)2.60717973
143poly(A)+ mRNA export from nucleus (GO:0016973)2.59742769
144macrophage activation (GO:0042116)2.59170983
145embryonic eye morphogenesis (GO:0048048)2.57230907
146regulation of phagocytosis (GO:0050764)2.56351931
147negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.56301044
148negative regulation of cell killing (GO:0031342)2.56301044
149adaptation of signaling pathway (GO:0023058)2.53703588
150maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.52400884
151germinal center formation (GO:0002467)2.51885532
152mitochondrial DNA metabolic process (GO:0032042)2.51551973
153regulation of B cell receptor signaling pathway (GO:0050855)2.48611411
154fatty acid transmembrane transport (GO:1902001)2.46204351
155positive regulation of mast cell degranulation (GO:0043306)2.45773280
156positive regulation of mast cell activation involved in immune response (GO:0033008)2.45773280
157positive regulation of sterol transport (GO:0032373)2.45343676
158positive regulation of cholesterol transport (GO:0032376)2.45343676
159cellular response to lithium ion (GO:0071285)2.45318725
160negative regulation of fatty acid biosynthetic process (GO:0045717)2.43271181
161regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.43169538
162regulation of vascular endothelial growth factor signaling pathway (GO:1900746)2.42492698
163positive regulation of antigen processing and presentation (GO:0002579)2.41107940
164brown fat cell differentiation (GO:0050873)2.40975386
165regulation of response to reactive oxygen species (GO:1901031)2.40242992
166positive regulation of myeloid leukocyte mediated immunity (GO:0002888)2.39133178
167negative regulation of cell cycle arrest (GO:0071157)2.38286198
168regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.38056464
169positive regulation of leukocyte degranulation (GO:0043302)2.36743232
170protein targeting to vacuole (GO:0006623)2.36614177
171protein targeting to lysosome (GO:0006622)2.36614177
172establishment of protein localization to vacuole (GO:0072666)2.36614177
173regulation of protein oligomerization (GO:0032459)2.35916333
174nodal signaling pathway (GO:0038092)2.35675681
175leukocyte cell-cell adhesion (GO:0007159)2.35638800
176negative regulation of nitric oxide biosynthetic process (GO:0045019)2.35511355

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1BP1_19119308_ChIP-ChIP_Hs578T_Human3.22021703
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.08334188
3IRF8_21731497_ChIP-ChIP_J774_Mouse3.07102112
4IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.83540448
5STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse2.81166966
6NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.78889403
7RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.65442616
8VDR_21846776_ChIP-Seq_THP-1_Human2.56080685
9NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.53081222
10KLF5_18264089_ChIP-ChIP_MESCs_Mouse2.52531587
11KLF4_18264089_ChIP-ChIP_MESCs_Mouse2.52531587
12KLF2_18264089_ChIP-ChIP_MESCs_Mouse2.52531587
13SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.46310473
14THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.38952988
15* VDR_24787735_ChIP-Seq_THP-1_Human2.24019404
16* STAT3_20064451_ChIP-Seq_CD4+T_Mouse2.22490445
17* IRF8_27001747_Chip-Seq_BMDM_Mouse2.21126593
18IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.19944282
19SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.17383274
20IRF8_22096565_ChIP-ChIP_GC-B_Human2.16647943
21LXR_22292898_ChIP-Seq_THP-1_Human2.16314689
22STAT4_19710469_ChIP-ChIP_TH1__Mouse2.13636941
23SPI1_23547873_ChIP-Seq_NB4_Human2.12232796
24* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.11467237
25KDM2B_26808549_Chip-Seq_SUP-B15_Human2.03515622
26SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.02629582
27VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.01450885
28NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.01325141
29CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.85540031
30ELK3_25401928_ChIP-Seq_HUVEC_Human1.84841380
31NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.80011731
32ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.78864938
33GATA1_22025678_ChIP-Seq_K562_Human1.73344815
34MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.67178618
35KDM2B_26808549_Chip-Seq_DND41_Human1.66597509
36* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.64421359
37MYB_21317192_ChIP-Seq_ERMYB_Mouse1.62794360
38CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.61557107
39TRIM28_21343339_ChIP-Seq_HEK293_Human1.60025241
40LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.58926463
41FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.58579247
42VDR_24763502_ChIP-Seq_THP-1_Human1.58509707
43PU_27001747_Chip-Seq_BMDM_Mouse1.55865133
44BRD4_27068464_Chip-Seq_AML-cells_Mouse1.55598753
45KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.54586357
46TCF7_22412390_ChIP-Seq_EML_Mouse1.52525498
47TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.51416507
48SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.49966467
49STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.49345497
50STAT6_21828071_ChIP-Seq_BEAS2B_Human1.49065186
51PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.48997396
52RACK7_27058665_Chip-Seq_MCF-7_Human1.48248582
53E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.47822085
54RARG_19884340_ChIP-ChIP_MEFs_Mouse1.46532206
55RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.46518859
56GATA1_19941827_ChIP-Seq_MEL_Mouse1.44985330
57LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.43908355
58MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.43696657
59PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.43500648
60EGR1_19374776_ChIP-ChIP_THP-1_Human1.42146366
61NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.41477458
62* SPI1_23127762_ChIP-Seq_K562_Human1.40950478
63FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.39277655
64GATA1_19941826_ChIP-Seq_K562_Human1.38452095
65KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.37417522
66MYC_22102868_ChIP-Seq_BL_Human1.33041718
67SMAD_19615063_ChIP-ChIP_OVARY_Human1.32273439
68RXR_22158963_ChIP-Seq_LIVER_Mouse1.31696838
69KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.31633240
70CLOCK_20551151_ChIP-Seq_293T_Human1.30990596
71* PU.1_20513432_ChIP-Seq_Bcells_Mouse1.29931793
72TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.29611550
73TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.29357216
74SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.29246378
75TCF3_18692474_ChIP-Seq_MEFs_Mouse1.28495715
76RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.28470359
77NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.28201967
78NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.27804632
79CDX2_20551321_ChIP-Seq_CACO-2_Human1.27525799
80STAT3_1855785_ChIP-Seq_MESCs_Mouse1.27047394
81ESR2_21235772_ChIP-Seq_MCF-7_Human1.25830512
82MAF_26560356_Chip-Seq_TH1_Human1.25412083
83KDM2B_26808549_Chip-Seq_K562_Human1.24152800
84GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.24034223
85* PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.23574855
86CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.23139491
87MYB_26560356_Chip-Seq_TH2_Human1.22528306
88NFIB_24661679_ChIP-Seq_LUNG_Mouse1.22381693
89LXR_22158963_ChIP-Seq_LIVER_Mouse1.22209133
90CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.22183975
91TCF3_18692474_ChIP-Seq_MESCs_Mouse1.22131249
92ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.22078435
93RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.21670567
94FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.21143341
95P300_27058665_Chip-Seq_ZR-75-30cells_Human1.20700864
96POU5F1_16518401_ChIP-PET_MESCs_Mouse1.20499569
97TP63_17297297_ChIP-ChIP_HaCaT_Human1.19664229
98SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.18792632
99* CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.17982949
100NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.17584012
101KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.16619419
102UTX_26944678_Chip-Seq_JUKART_Human1.15327747
103EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.14916320
104GATA1_22383799_ChIP-Seq_G1ME_Mouse1.14721432
105SPI1_20517297_ChIP-Seq_HL60_Human1.14345349
106TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.12651085
107TFEB_21752829_ChIP-Seq_HELA_Human1.12615277
108PPARA_22158963_ChIP-Seq_LIVER_Mouse1.12336919
109KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.11744435
110CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.10546496
111ZFP281_27345836_Chip-Seq_ESCs_Mouse1.09730220
112ERG_21242973_ChIP-ChIP_JURKAT_Human1.09669085
113RUNX1_22412390_ChIP-Seq_EML_Mouse1.09475145
114IKZF1_21737484_ChIP-ChIP_HCT116_Human1.08723584
115* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08640707
116POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.07698719
117GATA2_21666600_ChIP-Seq_HMVEC_Human1.06343655
118GATA2_22383799_ChIP-Seq_G1ME_Mouse1.05650928
119SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.05432773
120KDM2B_26808549_Chip-Seq_JURKAT_Human1.05172605
121HIF1A_21447827_ChIP-Seq_MCF-7_Human1.05121397
122STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.04827177
123RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.03157670
124ZFP281_18757296_ChIP-ChIP_E14_Mouse1.00898030
125DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.00685906
126FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.00519583
127* CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse1.00047188
128SCL_19346495_ChIP-Seq_HPC-7_Human0.99981889
129SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.99428861
130CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.98956162
131MYB_26560356_Chip-Seq_TH1_Human0.98480411
132STAT1_20625510_ChIP-Seq_HELA_Human0.98211176
133RXRA_24833708_ChIP-Seq_LIVER_Mouse0.97562879
134ESR1_21235772_ChIP-Seq_MCF-7_Human0.96965238
135CTCF_27219007_Chip-Seq_ERYTHROID_Human0.95687143
136MAF_26560356_Chip-Seq_TH2_Human0.94769739
137RUNX_20019798_ChIP-Seq_JUKART_Human0.94584640
138BCL6_27268052_Chip-Seq_Bcells_Human0.93640542
139* GATA2_19941826_ChIP-Seq_K562_Human0.91228127
140TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.91172833
141* GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.90196883
142GATA3_27048872_Chip-Seq_THYMUS_Human0.88605488
143SRY_22984422_ChIP-ChIP_TESTIS_Rat0.87224768
144BCOR_27268052_Chip-Seq_Bcells_Human0.86058224
145SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.85574942
146GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.81510288

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005670_abnormal_white_adipose3.66715935
2MP0008438_abnormal_cutaneous_collagen3.64123109
3MP0009278_abnormal_bone_marrow3.60567441
4MP0005058_abnormal_lysosome_morphology3.46970781
5MP0003191_abnormal_cellular_cholesterol2.77654366
6MP0005171_absent_coat_pigmentation2.77507235
7MP0003300_gastrointestinal_ulcer2.51546515
8MP0006082_CNS_inflammation2.46281062
9MP0003705_abnormal_hypodermis_morpholog2.37226704
10MP0000604_amyloidosis2.34155617
11MP0003172_abnormal_lysosome_physiology2.23016955
12MP0003828_pulmonary_edema2.19916948
13MP0004185_abnormal_adipocyte_glucose2.18652230
14MP0003724_increased_susceptibility_to2.18528156
15MP0004130_abnormal_muscle_cell2.08684995
16MP0003566_abnormal_cell_adhesion2.07842002
17MP0005666_abnormal_adipose_tissue2.05981131
18MP0002139_abnormal_hepatobiliary_system1.97179412
19MP0005397_hematopoietic_system_phenotyp1.95474846
20MP0001545_abnormal_hematopoietic_system1.95474846
21MP0000343_altered_response_to1.91033811
22MP0003075_altered_response_to1.90914111
23MP0003436_decreased_susceptibility_to1.88002072
24MP0003045_fibrosis1.84719654
25MP0009764_decreased_sensitivity_to1.78034331
26MP0002009_preneoplasia1.71270611
27MP0005076_abnormal_cell_differentiation1.70938928
28MP0009115_abnormal_fat_cell1.69518855
29MP0002166_altered_tumor_susceptibility1.68016718
30MP0005464_abnormal_platelet_physiology1.63729688
31MP0005275_abnormal_skin_tensile1.63680123
32MP0008057_abnormal_DNA_replication1.62240525
33MP0005310_abnormal_salivary_gland1.61523805
34MP0008469_abnormal_protein_level1.60656713
35MP0008260_abnormal_autophagy1.58927220
36MP0001853_heart_inflammation1.57204597
37MP0001835_abnormal_antigen_presentation1.53109929
38* MP0002419_abnormal_innate_immunity1.49020655
39MP0005451_abnormal_body_composition1.48773721
40MP0000858_altered_metastatic_potential1.45792692
41MP0001533_abnormal_skeleton_physiology1.42771969
42MP0005375_adipose_tissue_phenotype1.42650715
43MP0002006_tumorigenesis1.42581303
44MP0003279_aneurysm1.39098773
45MP0001790_abnormal_immune_system1.34354528
46MP0005387_immune_system_phenotype1.34354528
47MP0003453_abnormal_keratinocyte_physiol1.33596165
48MP0003448_altered_tumor_morphology1.33297899
49MP0006054_spinal_hemorrhage1.32839530
50MP0005023_abnormal_wound_healing1.32131341
51MP0003183_abnormal_peptide_metabolism1.31777853
52MP0005025_abnormal_response_to1.31514471
53MP0002971_abnormal_brown_adipose1.31408547
54MP0003303_peritoneal_inflammation1.28997506
55MP0005166_decreased_susceptibility_to1.28740126
56MP0000371_diluted_coat_color1.27239482
57MP0000920_abnormal_myelination1.25456268
58* MP0000716_abnormal_immune_system1.23295568
59MP0004233_abnormal_muscle_weight1.21956943
60MP0009840_abnormal_foam_cell1.21664566
61MP0004883_abnormal_blood_vessel1.19941233
62MP0003806_abnormal_nucleotide_metabolis1.19635808
63MP0002060_abnormal_skin_morphology1.19419466
64MP0002148_abnormal_hypersensitivity_rea1.17922390
65* MP0002405_respiratory_system_inflammati1.17824929
66MP0005390_skeleton_phenotype1.12460384
67MP0003329_amyloid_beta_deposits1.11497084
68MP0000767_abnormal_smooth_muscle1.10679194
69MP0005000_abnormal_immune_tolerance1.09699932
70MP0003690_abnormal_glial_cell1.09552302
71MP0002998_abnormal_bone_remodeling1.08724106
72MP0004272_abnormal_basement_membrane1.07652924
73MP0010352_gastrointestinal_tract_polyps1.07290376
74MP0005174_abnormal_tail_pigmentation1.06627194
75MP0002254_reproductive_system_inflammat1.05587367
76MP0010030_abnormal_orbit_morphology1.05436272
77* MP0002452_abnormal_antigen_presenting1.04760848
78MP0002168_other_aberrant_phenotype1.04646109
79MP0008995_early_reproductive_senescence1.03805738
80MP0000249_abnormal_blood_vessel1.02972241
81MP0001800_abnormal_humoral_immune1.00852624
82MP0003656_abnormal_erythrocyte_physiolo0.99926715
83MP0009333_abnormal_splenocyte_physiolog0.98700998
84MP0001915_intracranial_hemorrhage0.98645228
85MP0002282_abnormal_trachea_morphology0.97471073
86MP0005167_abnormal_blood-brain_barrier0.97426454
87MP0002398_abnormal_bone_marrow0.96320017
88MP0001542_abnormal_bone_strength0.96101261
89MP0005334_abnormal_fat_pad0.94661272
90MP0005365_abnormal_bile_salt0.93448485
91MP0010630_abnormal_cardiac_muscle0.93382039
92* MP0002429_abnormal_blood_cell0.92747192
93MP0003795_abnormal_bone_structure0.92366068
94MP0009763_increased_sensitivity_to0.91039127
95MP0010368_abnormal_lymphatic_system0.89815939
96MP0002933_joint_inflammation0.88633711
97MP0005508_abnormal_skeleton_morphology0.87955291
98MP0004510_myositis0.86395717
99MP0001958_emphysema0.85600082
100MP0002138_abnormal_hepatobiliary_system0.85283758
101MP0002723_abnormal_immune_serum0.84343130
102MP0000465_gastrointestinal_hemorrhage0.83642567
103MP0002970_abnormal_white_adipose0.82181486
104* MP0001845_abnormal_inflammatory_respons0.82082048
105MP0000689_abnormal_spleen_morphology0.82052938
106MP0002086_abnormal_extraembryonic_tissu0.81965226
107MP0002249_abnormal_larynx_morphology0.81085295
108MP0002277_abnormal_respiratory_mucosa0.80214696
109* MP0001819_abnormal_immune_cell0.80211918
110MP0005164_abnormal_response_to0.79995475
111* MP0002420_abnormal_adaptive_immunity0.79644010
112MP0002722_abnormal_immune_system0.79255775
113MP0003567_abnormal_fetal_cardiomyocyte0.77729886
114MP0002396_abnormal_hematopoietic_system0.76955215
115MP0001851_eye_inflammation0.76383305
116MP0005595_abnormal_vascular_smooth0.74730388
117MP0000490_abnormal_crypts_of0.73418289
118MP0001614_abnormal_blood_vessel0.73347919
119MP0005671_abnormal_response_to0.73344495
120MP0008004_abnormal_stomach_pH0.73114128
121* MP0000685_abnormal_immune_system0.72234301
122MP0000609_abnormal_liver_physiology0.71640021
123MP0002108_abnormal_muscle_morphology0.71571073
124MP0001663_abnormal_digestive_system0.71251554
125MP0002877_abnormal_melanocyte_morpholog0.71060740
126MP0005165_increased_susceptibility_to0.69925827
127MP0010155_abnormal_intestine_physiology0.69743372
128MP0003091_abnormal_cell_migration0.69232620
129MP0002295_abnormal_pulmonary_circulatio0.69209441
130MP0004782_abnormal_surfactant_physiolog0.67634962
131MP0002925_abnormal_cardiovascular_devel0.67459759
132MP0004947_skin_inflammation0.67328133
133MP0003634_abnormal_glial_cell0.67044310
134MP0002090_abnormal_vision0.66571378
135MP0009785_altered_susceptibility_to0.66134034
136MP0010329_abnormal_lipoprotein_level0.66070163
137MP0005257_abnormal_intraocular_pressure0.65615520
138MP0008874_decreased_physiological_sensi0.62549778
139MP0010307_abnormal_tumor_latency0.60916175
140MP0002896_abnormal_bone_mineralization0.58908585
141MP0001849_ear_inflammation0.57697703
142MP0005319_abnormal_enzyme/_coenzyme0.56805758
143MP0003763_abnormal_thymus_physiology0.56521829

Predicted human phenotypes

RankGene SetZ-score
1Systemic lupus erythematosus (HP:0002725)7.86151474
2Cerebral aneurysm (HP:0004944)5.26368132
3Complement deficiency (HP:0004431)5.24706188
4Glomerulonephritis (HP:0000099)5.18063011
5Pustule (HP:0200039)4.81551534
6Dysostosis multiplex (HP:0000943)4.80020723
7Abnormality of complement system (HP:0005339)4.77706918
8Mucopolysacchariduria (HP:0008155)4.46396422
9Urinary glycosaminoglycan excretion (HP:0003541)4.46396422
10Disinhibition (HP:0000734)4.35613791
11Abnormality of polysaccharide metabolism (HP:0011012)4.17483286
12Abnormality of glycosaminoglycan metabolism (HP:0004371)4.17483286
13Abnormality of mucopolysaccharide metabolism (HP:0011020)4.17483286
14Asymmetric septal hypertrophy (HP:0001670)3.95542166
15Mutism (HP:0002300)3.93173314
16Nephritis (HP:0000123)3.82037590
17Alopecia of scalp (HP:0002293)3.58389248
18Recurrent abscess formation (HP:0002722)3.42880341
19Joint stiffness (HP:0001387)3.38245430
20Abnormality of the vasculature of the conjunctiva (HP:0008054)3.30917221
21Mediastinal lymphadenopathy (HP:0100721)3.26615093
22Turricephaly (HP:0000262)3.24877635
23Intestinal fistula (HP:0100819)3.21193705
24Recurrent gram-negative bacterial infections (HP:0005420)3.20830105
25Rectal fistula (HP:0100590)3.20307507
26Rectovaginal fistula (HP:0000143)3.20307507
27Neurofibrillary tangles (HP:0002185)3.15389163
28Ulnar bowing (HP:0003031)3.08705400
29Vaginal fistula (HP:0004320)3.08530253
30Eczematoid dermatitis (HP:0000976)3.04143511
31Increased IgM level (HP:0003496)3.03292638
32Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)3.01926693
33Purpura (HP:0000979)2.87712183
34Myocardial infarction (HP:0001658)2.86459681
35Myositis (HP:0100614)2.85782122
36Orchitis (HP:0100796)2.85635505
37Annular pancreas (HP:0001734)2.85517215
38Polycythemia (HP:0001901)2.83091924
39Recurrent skin infections (HP:0001581)2.75924958
40Nuclear cataract (HP:0100018)2.71694120
41Spondylolisthesis (HP:0003302)2.71320030
42Recurrent bacterial skin infections (HP:0005406)2.70854556
43Obstructive lung disease (HP:0006536)2.70798714
44Chronic obstructive pulmonary disease (HP:0006510)2.70798714
45Upper motor neuron abnormality (HP:0002127)2.70239198
46Agnosia (HP:0010524)2.66174801
47Shallow orbits (HP:0000586)2.65778538
48Rib fusion (HP:0000902)2.63700365
49Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.56721885
50Hematochezia (HP:0002573)2.54576188
51Retrobulbar optic neuritis (HP:0100654)2.54273786
52Optic neuritis (HP:0100653)2.54273786
53Neuronal loss in central nervous system (HP:0002529)2.53457807
54Coarse hair (HP:0002208)2.53040124
55Colitis (HP:0002583)2.50211864
56Increased serum ferritin (HP:0003281)2.44027636
57Amyloidosis (HP:0011034)2.43016640
58Albinism (HP:0001022)2.40924951
59Spontaneous hematomas (HP:0007420)2.39531064
60Orthostatic hypotension (HP:0001278)2.39269055
61Inappropriate behavior (HP:0000719)2.38853531
62Increased cerebral lipofuscin (HP:0011813)2.38342134
63Vacuolated lymphocytes (HP:0001922)2.38291993
64Apathy (HP:0000741)2.37904282
65Growth hormone excess (HP:0000845)2.36168522
66Diminished motivation (HP:0000745)2.34836802
67Stomatitis (HP:0010280)2.31766252
68Retinal atrophy (HP:0001105)2.31291472
69Pulmonary infiltrates (HP:0002113)2.30718109
70Coronal craniosynostosis (HP:0004440)2.30344705
71Short humerus (HP:0005792)2.27297800
72Hemoptysis (HP:0002105)2.27189895
73Arterial tortuosity (HP:0005116)2.25143800
74Cerebral inclusion bodies (HP:0100314)2.24654027
75Premature skin wrinkling (HP:0100678)2.24253970
76Vertebral hypoplasia (HP:0008417)2.20985240
77Aplasia/Hypoplasia of the vertebrae (HP:0008515)2.20985240
78Malnutrition (HP:0004395)2.20011581
79Progressive neurologic deterioration (HP:0002344)2.19727438
80Conjunctival telangiectasia (HP:0000524)2.19102985
81Pathologic fracture (HP:0002756)2.18240189
82Hepatosplenomegaly (HP:0001433)2.16134007
83Abnormality of the nasal mucosa (HP:0000433)2.14659589
84Meningitis (HP:0001287)2.13259686
85Cervical subluxation (HP:0003308)2.13023916
86Axonal loss (HP:0003447)2.12942278
87Metaphyseal irregularity (HP:0003025)2.12486293
88Concave nail (HP:0001598)2.12204105
89Petechiae (HP:0000967)2.12170370
90Large for gestational age (HP:0001520)2.10881532
91Recurrent cutaneous fungal infections (HP:0011370)2.10090528
92Chronic mucocutaneous candidiasis (HP:0002728)2.10090528
93Abnormality of glycolipid metabolism (HP:0010969)2.10070047
94Abnormality of liposaccharide metabolism (HP:0010968)2.10070047
95Abnormality of glycosphingolipid metabolism (HP:0004343)2.10070047
96Personality changes (HP:0000751)2.09028241
97Vascular tortuosity (HP:0004948)2.08647150
98Urethral obstruction (HP:0000796)2.07971286
99Bulbar palsy (HP:0001283)2.05368406
100Aortic aneurysm (HP:0004942)2.05361414
101Increased CSF protein (HP:0002922)2.04947948
102Male infertility (HP:0003251)2.04698776
103Prolonged bleeding time (HP:0003010)2.02694747
104Broad metatarsal (HP:0001783)2.02570149
105Urticaria (HP:0001025)2.02467180
106Dementia (HP:0000726)2.02352860
107Abnormality of iron homeostasis (HP:0011031)2.01822433
108Bowed forearm bones (HP:0003956)2.01806258
109Bowing of the arm (HP:0006488)2.01806258
110Increased neuronal autofluorescent lipopigment (HP:0002074)2.01300565
111Premature loss of primary teeth (HP:0006323)2.01169516
112Basal ganglia calcification (HP:0002135)2.01116752
113Aplasia/hypoplasia of the humerus (HP:0006507)2.00181187
114Vertebral compression fractures (HP:0002953)2.00137055
115Vasculitis (HP:0002633)1.99877908
116Intestinal atresia (HP:0011100)1.99465539
117T lymphocytopenia (HP:0005403)1.98660598
118Cellulitis (HP:0100658)1.97879904
119Recurrent viral infections (HP:0004429)1.96511545
120Polyneuropathy (HP:0001271)1.95878818
121Abnormal hemoglobin (HP:0011902)1.95463070
122Progressive visual loss (HP:0000529)1.94916887
123Acanthosis nigricans (HP:0000956)1.94668848
124Aneurysm (HP:0002617)1.94111708
125Global brain atrophy (HP:0002283)1.93828209
126Abnormality of male internal genitalia (HP:0000022)1.92383062
127Bone pain (HP:0002653)1.91098938
128Loss of speech (HP:0002371)1.90907220
129Thoracic kyphosis (HP:0002942)1.90854289
130Ovoid vertebral bodies (HP:0003300)1.90563465
131Oligomenorrhea (HP:0000876)1.89671595
132Gingivitis (HP:0000230)1.87895232
133Peripheral demyelination (HP:0011096)1.87780576
134Aortic dissection (HP:0002647)1.87407073
135Increased connective tissue (HP:0009025)1.87114536
136Abnormality of macrophages (HP:0004311)1.86341319
137Spinal muscular atrophy (HP:0007269)1.85868379
138Restrictive lung disease (HP:0002091)1.85349707
139Autoimmune thrombocytopenia (HP:0001973)1.84881008
140Acrocyanosis (HP:0001063)1.84488493
141Striae distensae (HP:0001065)1.82585062
142Facial hemangioma (HP:0000329)1.82375948
143Abnormality of T cell number (HP:0011839)1.81442301
144Cardiomegaly (HP:0001640)1.81290873
145Abnormality of the periventricular white matter (HP:0002518)1.80410674
146Prostate neoplasm (HP:0100787)1.79723735
147Recurrent fungal infections (HP:0002841)1.79154040
148Generalized amyotrophy (HP:0003700)1.79051216
149Muscle fibrillation (HP:0010546)1.79030717
150Mucosal telangiectasiae (HP:0100579)1.78042682
151Gastrointestinal infarctions (HP:0005244)1.77889106
152Keratoconjunctivitis sicca (HP:0001097)1.77739379
153Menorrhagia (HP:0000132)1.77664418
154Epistaxis (HP:0000421)1.77407836
155Inflammation of the large intestine (HP:0002037)1.76834249
156Clumsiness (HP:0002312)1.75884538
157IgA deficiency (HP:0002720)1.74699371
158Hypotrichosis (HP:0001006)1.74322072
159Nasal polyposis (HP:0100582)1.71994443
160Hypochromic microcytic anemia (HP:0004840)1.70756905
161Cheilitis (HP:0100825)1.68485915
162Tongue fasciculations (HP:0001308)1.67123982
163Hemorrhage of the eye (HP:0011885)1.66568859
164Poikiloderma (HP:0001029)1.66002142
165Deformed sella turcica (HP:0002681)1.65471820

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPK154.38194368
2ICK4.33069438
3DDR23.72477037
4MAP3K63.62822917
5TGFBR23.07443201
6CAMK1D2.89057113
7CSK2.64955990
8MATK2.55096583
9FGR2.52599610
10MAP3K112.41948822
11BMX2.40022582
12NME22.20332768
13TRIB32.18266557
14MST1R2.01348189
15PINK11.99903882
16CAMK1G1.99508036
17PDGFRA1.93302717
18RIPK11.83190494
19TYRO31.73310570
20MAP3K131.70262806
21ERN11.68414790
22PRKD21.62802077
23ACVR1B1.60935692
24BLK1.59574898
25TRPM71.59099825
26CAMKK21.56440179
27YES11.51156970
28IKBKE1.47264406
29MAP3K31.44291566
30DAPK11.43262083
31FES1.38191461
32CDK61.35878260
33TAOK21.34789582
34SYK1.33847199
35TYK21.32281045
36TAOK11.21106742
37RPS6KC11.17381054
38RPS6KL11.17381054
39PIM21.16662414
40MAP3K101.13443309
41MAP4K11.12942425
42DYRK1B1.11993258
43GSK3A1.10400923
44ABL21.10038733
45SIK11.09577149
46RPS6KA61.08948267
47PIM11.08181167
48MOS1.01443605
49NEK91.00492918
50TTN0.99824618
51TIE10.95531083
52MAP3K10.94656158
53CSF1R0.94186174
54TGFBR10.93318439
55EPHB10.92223264
56CDK120.91343674
57GRK70.91073889
58TESK20.90508635
59BTK0.89951116
60PRKAA20.85986234
61STK100.84381811
62PAK40.81665343
63TESK10.81384798
64PRPF4B0.81143601
65MET0.81121827
66ADRBK20.80434817
67MAPK110.80072646
68JAK10.79937033
69CDK70.79074820
70FGFR40.77595642
71EPHA20.74514959
72TBK10.71876246
73RIPK40.70814035
74IRAK30.70294931
75ZAP700.70233889
76DMPK0.69645342
77PDGFRB0.69588796
78PDPK10.69504313
79LATS20.69264605
80UHMK10.67681524
81PHKG20.67420649
82PHKG10.67420649
83LATS10.66927831
84MTOR0.66614066
85EGFR0.65367945
86LYN0.65031601
87IKBKB0.64811777
88STK30.64629584
89BMPR20.63486627
90HCK0.62200852
91CDC42BPA0.61781022
92PRKAA10.60721083
93IRAK40.60098852
94JAK20.59919894
95EPHB20.59496434
96MAPK70.58676143
97LCK0.57612285
98SIK30.57140654
99MAP2K30.56566504
100PIK3CG0.55965214
101SIK20.55688880
102PDK10.53994036
103RPS6KA20.53719608
104MARK20.52423975
105MAP3K50.50440858
106AKT30.49426584
107CAMKK10.47095609
108DAPK20.46243663
109KIT0.46238236
110KSR20.45947428
111RPS6KA10.45603342
112ITK0.45161174
113KSR10.44826695
114PRKG20.44517850
115PRKD10.42840761
116EPHA30.42495565
117IRAK10.42216126
118MAP2K60.41563711
119INSR0.41480779
120MARK30.41353697
121STK380.40697351
122ARAF0.40251898
123TAOK30.40235715
124CHUK0.40110008
125PDK20.40003559
126MAPK40.38201198
127FYN0.38135810
128FGFR30.38001214
129IRAK20.37925865
130MAPKAPK20.37574153
131JAK30.36085001
132HIPK20.35491991
133TXK0.34030197
134CDK40.32436669
135PRKCH0.32313737
136MAPK30.31199713
137ABL10.30687884
138MAPK10.29573578
139MAPK120.28988467
140MAP3K140.28349465
141PAK20.28220867
142TNK20.27670549
143PRKCD0.26203776
144MAPKAPK30.26166483

Predicted pathways (KEGG)

RankGene SetZ-score
1Staphylococcus aureus infection_Homo sapiens_hsa051505.39076562
2Fatty acid biosynthesis_Homo sapiens_hsa000614.37370462
3Glycosaminoglycan degradation_Homo sapiens_hsa005313.50299624
4Other glycan degradation_Homo sapiens_hsa005112.82373415
5Allograft rejection_Homo sapiens_hsa053302.62150857
6Asthma_Homo sapiens_hsa053102.42556111
7Autoimmune thyroid disease_Homo sapiens_hsa053202.31547183
8Complement and coagulation cascades_Homo sapiens_hsa046102.13574734
9Lysosome_Homo sapiens_hsa041422.01689810
10Pertussis_Homo sapiens_hsa051331.89087014
11Notch signaling pathway_Homo sapiens_hsa043301.88654634
12Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.85668234
13Type I diabetes mellitus_Homo sapiens_hsa049401.85331235
14Leishmaniasis_Homo sapiens_hsa051401.78607150
15Adherens junction_Homo sapiens_hsa045201.76136395
16Legionellosis_Homo sapiens_hsa051341.71383973
17Osteoclast differentiation_Homo sapiens_hsa043801.53577528
18Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.50701052
19Malaria_Homo sapiens_hsa051441.47772068
20Prion diseases_Homo sapiens_hsa050201.45830022
21Caffeine metabolism_Homo sapiens_hsa002321.38324737
22Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.36485117
23NOD-like receptor signaling pathway_Homo sapiens_hsa046211.34016806
24Viral myocarditis_Homo sapiens_hsa054161.32972392
25mTOR signaling pathway_Homo sapiens_hsa041501.26580050
26Fatty acid metabolism_Homo sapiens_hsa012121.24804835
27Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.24212698
28Base excision repair_Homo sapiens_hsa034101.21019884
29Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.19787253
30AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049331.17185321
31TGF-beta signaling pathway_Homo sapiens_hsa043501.13344088
32Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.13120364
33PPAR signaling pathway_Homo sapiens_hsa033201.12915011
34Tuberculosis_Homo sapiens_hsa051521.12165335
35Toll-like receptor signaling pathway_Homo sapiens_hsa046201.10719612
36B cell receptor signaling pathway_Homo sapiens_hsa046621.10443755
37Shigellosis_Homo sapiens_hsa051311.09589461
38Longevity regulating pathway - mammal_Homo sapiens_hsa042111.07738792
39Regulation of actin cytoskeleton_Homo sapiens_hsa048101.06669678
40Transcriptional misregulation in cancer_Homo sapiens_hsa052021.04522121
41Acute myeloid leukemia_Homo sapiens_hsa052211.04249418
42Collecting duct acid secretion_Homo sapiens_hsa049661.04017697
43Focal adhesion_Homo sapiens_hsa045101.03991906
44Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.02976921
45Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.01788239
46Toxoplasmosis_Homo sapiens_hsa051451.01043143
47Chronic myeloid leukemia_Homo sapiens_hsa052200.99772099
48Measles_Homo sapiens_hsa051620.99315659
49Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.99005109
50Lysine degradation_Homo sapiens_hsa003100.97098717
51Amoebiasis_Homo sapiens_hsa051460.96510518
52Salmonella infection_Homo sapiens_hsa051320.91754655
53Phagosome_Homo sapiens_hsa041450.90130806
54Small cell lung cancer_Homo sapiens_hsa052220.89635195
55Chemokine signaling pathway_Homo sapiens_hsa040620.88413885
56Mineral absorption_Homo sapiens_hsa049780.87289744
57Hippo signaling pathway_Homo sapiens_hsa043900.85411182
58Adipocytokine signaling pathway_Homo sapiens_hsa049200.83535820
59Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.82901656
60ECM-receptor interaction_Homo sapiens_hsa045120.82745316
61Circadian rhythm_Homo sapiens_hsa047100.82673252
62Hepatitis C_Homo sapiens_hsa051600.81607623
63Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.81434078
64VEGF signaling pathway_Homo sapiens_hsa043700.81395195
65Arachidonic acid metabolism_Homo sapiens_hsa005900.81001820
66Proteoglycans in cancer_Homo sapiens_hsa052050.80994018
67AMPK signaling pathway_Homo sapiens_hsa041520.79173721
68Pentose and glucuronate interconversions_Homo sapiens_hsa000400.78636624
69African trypanosomiasis_Homo sapiens_hsa051430.78254719
70Dorso-ventral axis formation_Homo sapiens_hsa043200.77903004
71Pancreatic cancer_Homo sapiens_hsa052120.76677808
72Hematopoietic cell lineage_Homo sapiens_hsa046400.76199095
73Primary immunodeficiency_Homo sapiens_hsa053400.73121157
74Colorectal cancer_Homo sapiens_hsa052100.71798636
75Leukocyte transendothelial migration_Homo sapiens_hsa046700.71191223
76Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70996222
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.70005272
78Jak-STAT signaling pathway_Homo sapiens_hsa046300.69987012
79Platelet activation_Homo sapiens_hsa046110.69436652
80Bladder cancer_Homo sapiens_hsa052190.68413012
81T cell receptor signaling pathway_Homo sapiens_hsa046600.67688808
82Sphingolipid signaling pathway_Homo sapiens_hsa040710.66767109
83Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.66460752
84Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66184985
85Graft-versus-host disease_Homo sapiens_hsa053320.65810270
86Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.64989648
87Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.64779307
88Endocytosis_Homo sapiens_hsa041440.64153631
89Sphingolipid metabolism_Homo sapiens_hsa006000.62943452
90Apoptosis_Homo sapiens_hsa042100.62259594
91Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.62255136
92Insulin resistance_Homo sapiens_hsa049310.62115782
93ABC transporters_Homo sapiens_hsa020100.62047061
94Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.62022586
95Herpes simplex infection_Homo sapiens_hsa051680.60757882
96Antigen processing and presentation_Homo sapiens_hsa046120.60463144
97Insulin signaling pathway_Homo sapiens_hsa049100.59544196
98Hepatitis B_Homo sapiens_hsa051610.58662689
99Hedgehog signaling pathway_Homo sapiens_hsa043400.58170565
100NF-kappa B signaling pathway_Homo sapiens_hsa040640.57074160
101Vibrio cholerae infection_Homo sapiens_hsa051100.56914419
102Mismatch repair_Homo sapiens_hsa034300.56404889
103Glycerolipid metabolism_Homo sapiens_hsa005610.56188326
104Rap1 signaling pathway_Homo sapiens_hsa040150.55256856
105HIF-1 signaling pathway_Homo sapiens_hsa040660.53266865
106PI3K-Akt signaling pathway_Homo sapiens_hsa041510.52980966
107Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.50236344
108Arginine and proline metabolism_Homo sapiens_hsa003300.50036304
109Neurotrophin signaling pathway_Homo sapiens_hsa047220.50029530
1102-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.49912559
111Influenza A_Homo sapiens_hsa051640.49770677
112TNF signaling pathway_Homo sapiens_hsa046680.48655827
113Prolactin signaling pathway_Homo sapiens_hsa049170.48464304
114SNARE interactions in vesicular transport_Homo sapiens_hsa041300.48392320
115Galactose metabolism_Homo sapiens_hsa000520.47787523
116Pathways in cancer_Homo sapiens_hsa052000.45954559
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.44486129
118MicroRNAs in cancer_Homo sapiens_hsa052060.44230001
119Intestinal immune network for IgA production_Homo sapiens_hsa046720.44007149
120Epstein-Barr virus infection_Homo sapiens_hsa051690.41873726
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.41625130
122Renal cell carcinoma_Homo sapiens_hsa052110.40750080
123MAPK signaling pathway_Homo sapiens_hsa040100.40532526
124Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.39625438
125Systemic lupus erythematosus_Homo sapiens_hsa053220.39396350
126Phospholipase D signaling pathway_Homo sapiens_hsa040720.39292117
127Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.39153926
128Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.38443108
129Rheumatoid arthritis_Homo sapiens_hsa053230.37652261
130Basal cell carcinoma_Homo sapiens_hsa052170.37264620
131HTLV-I infection_Homo sapiens_hsa051660.33715782
132Renin-angiotensin system_Homo sapiens_hsa046140.33310277
133GnRH signaling pathway_Homo sapiens_hsa049120.32837710
134Non-small cell lung cancer_Homo sapiens_hsa052230.27374060
135Sulfur metabolism_Homo sapiens_hsa009200.20980533
136Viral carcinogenesis_Homo sapiens_hsa052030.18048700
137Synaptic vesicle cycle_Homo sapiens_hsa047210.16967230
138Carbohydrate digestion and absorption_Homo sapiens_hsa049730.16456153

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