CMPK1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1UDP-N-acetylglucosamine metabolic process (GO:0006047)4.93693331
2signal peptide processing (GO:0006465)4.62641833
3Golgi transport vesicle coating (GO:0048200)4.56682965
4COPI coating of Golgi vesicle (GO:0048205)4.56682965
5L-phenylalanine catabolic process (GO:0006559)3.96406022
6erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.96406022
7L-phenylalanine metabolic process (GO:0006558)3.77151109
8erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.77151109
9very-low-density lipoprotein particle assembly (GO:0034379)3.74843435
10negative regulation of protein localization to plasma membrane (GO:1903077)3.62831529
11maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.61785392
12Arp2/3 complex-mediated actin nucleation (GO:0034314)3.50471727
13protein retention in ER lumen (GO:0006621)3.48883785
143-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.48792640
15purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.48792640
16peptide catabolic process (GO:0043171)3.44406537
17negative regulation of establishment of protein localization to plasma membrane (GO:0090005)3.42890873
18intestinal absorption (GO:0050892)3.36907086
19nucleotide-sugar metabolic process (GO:0009225)3.36238617
20regulation of transforming growth factor beta1 production (GO:0032908)3.33451309
21nitrogen cycle metabolic process (GO:0071941)3.30553651
22regulation of metalloenzyme activity (GO:0048552)3.28106506
23regulation of early endosome to late endosome transport (GO:2000641)3.25850668
24nucleotide-sugar biosynthetic process (GO:0009226)3.22277255
25COPII vesicle coating (GO:0048208)3.20733927
26aldehyde catabolic process (GO:0046185)3.19379906
27protein maturation by protein folding (GO:0022417)3.17117823
28protein localization to endosome (GO:0036010)3.13376494
29intestinal cholesterol absorption (GO:0030299)3.13298517
30desmosome organization (GO:0002934)3.13140610
31aromatic amino acid family catabolic process (GO:0009074)3.12001488
32nucleobase catabolic process (GO:0046113)3.11678819
33actin nucleation (GO:0045010)3.08856076
34lipoprotein transport (GO:0042953)3.06480991
35uronic acid metabolic process (GO:0006063)3.05721504
36glucuronate metabolic process (GO:0019585)3.05721504
37sequestering of metal ion (GO:0051238)3.01833949
38pyrimidine nucleobase catabolic process (GO:0006208)2.99013164
39cellular ketone body metabolic process (GO:0046950)2.97798541
40hypotonic response (GO:0006971)2.97355912
41cell adhesion mediated by integrin (GO:0033627)2.96614009
42cysteine metabolic process (GO:0006534)2.94707894
43lipopolysaccharide biosynthetic process (GO:0009103)2.92344726
44embryonic process involved in female pregnancy (GO:0060136)2.90487247
45ethanol oxidation (GO:0006069)2.90163933
46triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.86702077
47protein-lipid complex assembly (GO:0065005)2.86395870
48ER overload response (GO:0006983)2.85750060
49cofactor catabolic process (GO:0051187)2.85593418
50sulfur amino acid catabolic process (GO:0000098)2.85272620
51epoxygenase P450 pathway (GO:0019373)2.84978054
52plasma lipoprotein particle assembly (GO:0034377)2.83948054
53low-density lipoprotein particle remodeling (GO:0034374)2.83632154
54positive regulation of substrate adhesion-dependent cell spreading (GO:1900026)2.83389157
55protein N-linked glycosylation via asparagine (GO:0018279)2.83351211
56cellular glucuronidation (GO:0052695)2.83131543
57membrane budding (GO:0006900)2.81688751
58NADH metabolic process (GO:0006734)2.81010907
59respiratory burst (GO:0045730)2.80092136
60drug transmembrane transport (GO:0006855)2.79673819
61peptidyl-asparagine modification (GO:0018196)2.76711629
62maintenance of gastrointestinal epithelium (GO:0030277)2.75773155
63regulation of protein activation cascade (GO:2000257)2.75308500
64flavonoid metabolic process (GO:0009812)2.74169589
65diterpenoid biosynthetic process (GO:0016102)2.73962977
66regulation of protein localization to plasma membrane (GO:1903076)2.72432865
67regulation of complement activation (GO:0030449)2.72297807
68regulation of cholesterol homeostasis (GO:2000188)2.71911532
69ER-associated ubiquitin-dependent protein catabolic process (GO:0030433)2.71884162
70fibrinolysis (GO:0042730)2.71102091
71regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)2.69769599
72lipopolysaccharide metabolic process (GO:0008653)2.68964361
73mitochondrial calcium ion transport (GO:0006851)2.68652324
74regulation of Golgi to plasma membrane protein transport (GO:0042996)2.66915853
75platelet degranulation (GO:0002576)2.66085420
76positive regulation of extracellular matrix organization (GO:1903055)2.65936577
77neutrophil activation involved in immune response (GO:0002283)2.65765031
78regulation of establishment of protein localization to plasma membrane (GO:0090003)2.64467612
79coenzyme catabolic process (GO:0009109)2.62785494
80regulation of cholesterol esterification (GO:0010872)2.62564278
81protein N-linked glycosylation (GO:0006487)2.62297137
82vesicle coating (GO:0006901)2.61384453
83blood coagulation, intrinsic pathway (GO:0007597)2.59260672
84alkaloid metabolic process (GO:0009820)2.58681818
85regulation of substrate adhesion-dependent cell spreading (GO:1900024)2.58435008
86phospholipid scrambling (GO:0017121)2.58337974
87bile acid and bile salt transport (GO:0015721)2.58335214
88cyclooxygenase pathway (GO:0019371)2.55685455
89barbed-end actin filament capping (GO:0051016)2.53997659
90positive regulation of hemostasis (GO:1900048)2.53955703
91positive regulation of blood coagulation (GO:0030194)2.53955703
92ribonucleoside bisphosphate metabolic process (GO:0033875)2.53513189
93nucleoside bisphosphate metabolic process (GO:0033865)2.53513189
94purine nucleoside bisphosphate metabolic process (GO:0034032)2.53513189
95negative regulation of blood coagulation (GO:0030195)2.53421836
96negative regulation of hemostasis (GO:1900047)2.53421836
97proline biosynthetic process (GO:0006561)2.53131312
98regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714)2.52830504
99retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.52662595
100fructose metabolic process (GO:0006000)2.51597070
101negative regulation of protein activation cascade (GO:2000258)2.51443298
102hormone catabolic process (GO:0042447)2.50301047
103daunorubicin metabolic process (GO:0044597)2.49782671
104polyketide metabolic process (GO:0030638)2.49782671
105doxorubicin metabolic process (GO:0044598)2.49782671
106GDP-mannose metabolic process (GO:0019673)2.49467497
107thrombin receptor signaling pathway (GO:0070493)2.49213578
108response to thyroid hormone (GO:0097066)2.48916150
109long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.48667664
110iron ion import (GO:0097286)2.48458967
111drug transport (GO:0015893)2.47898780
112negative regulation of fibrinolysis (GO:0051918)2.47050914
113negative regulation of coagulation (GO:0050819)2.46996820
114ethanol metabolic process (GO:0006067)2.46913595
115ketone body metabolic process (GO:1902224)2.45457210
116alpha-linolenic acid metabolic process (GO:0036109)2.44518823
117peroxisome fission (GO:0016559)2.44298733
118glutamine family amino acid biosynthetic process (GO:0009084)2.43670040
119progesterone metabolic process (GO:0042448)2.43126669
120cholesterol biosynthetic process (GO:0006695)2.42004244
121positive regulation of macrophage differentiation (GO:0045651)2.41269896
122angiotensin maturation (GO:0002003)2.40456549
123regulation of triglyceride catabolic process (GO:0010896)2.39225584
124homocysteine metabolic process (GO:0050667)2.39044683
125positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.38805863
126triglyceride catabolic process (GO:0019433)2.38118387
127protein-lipid complex subunit organization (GO:0071825)2.37872634
128long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.37573735
129regulation of extracellular matrix disassembly (GO:0010715)2.37317192
130positive regulation of coagulation (GO:0050820)2.36869917
131positive regulation of endothelial cell apoptotic process (GO:2000353)2.36102714
132negative regulation of wound healing (GO:0061045)2.35281165
133fatty-acyl-CoA metabolic process (GO:0035337)2.34780427
134high-density lipoprotein particle remodeling (GO:0034375)2.34651435
135glycoside metabolic process (GO:0016137)2.34341434
136peptidyl-glutamic acid carboxylation (GO:0017187)2.34252774
137protein carboxylation (GO:0018214)2.34252774
138negative regulation of complement activation (GO:0045916)2.33743961
139plasma lipoprotein particle organization (GO:0071827)2.33478713
140fatty-acyl-CoA biosynthetic process (GO:0046949)2.32950624
141negative regulation of erythrocyte differentiation (GO:0045647)2.32702474
142regulation of lipoprotein metabolic process (GO:0050746)2.32679114
143primary alcohol catabolic process (GO:0034310)2.31281958
144glycosphingolipid catabolic process (GO:0046479)2.31092434
145tryptophan metabolic process (GO:0006568)2.31000907
146complement activation, classical pathway (GO:0006958)2.30957675
147endocrine pancreas development (GO:0031018)2.30768931
148NADPH regeneration (GO:0006740)2.30483837
149thioester biosynthetic process (GO:0035384)2.30016810
150acyl-CoA biosynthetic process (GO:0071616)2.30016810
151negative regulation of fatty acid transport (GO:2000192)2.29781168
152cellular response to thyroid hormone stimulus (GO:0097067)2.29754829
153response to vitamin E (GO:0033197)2.29506871
154tryptophan catabolic process (GO:0006569)2.28383710
155indole-containing compound catabolic process (GO:0042436)2.28383710
156indolalkylamine catabolic process (GO:0046218)2.28383710
157hydrogen peroxide biosynthetic process (GO:0050665)2.28064585
158drug catabolic process (GO:0042737)2.27806750
159peptide hormone processing (GO:0016486)2.27406158
160sulfation (GO:0051923)2.27404448
161acylglycerol catabolic process (GO:0046464)2.25993923
162neutral lipid catabolic process (GO:0046461)2.25993923
163bile acid metabolic process (GO:0008206)2.25930368
164NADP metabolic process (GO:0006739)2.25122418
165aromatic amino acid family metabolic process (GO:0009072)2.21872578
166bile acid biosynthetic process (GO:0006699)2.21799132
167cytidine deamination (GO:0009972)2.21021189
168cytidine metabolic process (GO:0046087)2.21021189
169cytidine catabolic process (GO:0006216)2.21021189
170fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.20913101
171urea metabolic process (GO:0019627)2.20724636
172urea cycle (GO:0000050)2.20724636
173transcytosis (GO:0045056)2.20667829
174phenylpropanoid metabolic process (GO:0009698)2.20409552

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse5.07625977
2PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.98163640
3FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse3.86757877
4RXR_22158963_ChIP-Seq_LIVER_Mouse3.72971316
5NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.41501513
6IRF8_22096565_ChIP-ChIP_GC-B_Human3.28059359
7TP63_17297297_ChIP-ChIP_HaCaT_Human3.13140293
8PPARA_22158963_ChIP-Seq_LIVER_Mouse3.02406802
9GATA1_22025678_ChIP-Seq_K562_Human2.75376021
10CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.73273746
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.72315854
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.70801938
13EGR1_23403033_ChIP-Seq_LIVER_Mouse2.69670732
14IRF8_21731497_ChIP-ChIP_J774_Mouse2.65221722
15TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse2.61204413
16LXR_22158963_ChIP-Seq_LIVER_Mouse2.57280631
17STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse2.52254782
18EGR1_19374776_ChIP-ChIP_THP-1_Human2.34695477
19SOX2_20726797_ChIP-Seq_SW620_Human2.25424110
20MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.23571807
21Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse2.21797337
22NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.18108934
23SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.15882600
24* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human2.04841020
25IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.03473546
26SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse2.01548301
27IRF8_27001747_Chip-Seq_BMDM_Mouse2.00466426
28CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.99269655
29FOXO3_23340844_ChIP-Seq_DLD1_Human1.97020040
30CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.96984977
31MYB_21317192_ChIP-Seq_ERMYB_Mouse1.96782693
32GABP_17652178_ChIP-ChIP_JURKAT_Human1.96322326
33GATA2_21666600_ChIP-Seq_HMVEC_Human1.94687108
34TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.94221279
35FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.90272003
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.86024959
37* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.85649745
38AR_21909140_ChIP-Seq_LNCAP_Human1.83836968
39RARG_19884340_ChIP-ChIP_MEFs_Mouse1.83819189
40PPAR_26484153_Chip-Seq_NCI-H1993_Human1.83812643
41SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.83653947
42SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.83653947
43GATA1_19941826_ChIP-Seq_K562_Human1.81666695
44ZNF263_19887448_ChIP-Seq_K562_Human1.77671302
45* KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.77269143
46GATA2_19941826_ChIP-Seq_K562_Human1.72615071
47NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.72300344
48TAF15_26573619_Chip-Seq_HEK293_Human1.71886596
49TRIM28_21343339_ChIP-Seq_HEK293_Human1.69485777
50SOX2_27498859_Chip-Seq_STOMACH_Mouse1.66266830
51PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.62934954
52FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.61767515
53CLOCK_20551151_ChIP-Seq_293T_Human1.55650983
54NRF2_20460467_ChIP-Seq_MEFs_Mouse1.54940109
55NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.54940109
56GATA6_25053715_ChIP-Seq_YYC3_Human1.53373914
57KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.50452270
58SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.48453570
59SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.46050904
60TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.43324825
61TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.42508449
62ELK1_19687146_ChIP-ChIP_HELA_Human1.41349382
63CDX2_20551321_ChIP-Seq_CACO-2_Human1.40608810
64GATA4_25053715_ChIP-Seq_YYC3_Human1.38789172
65EGR1_19032775_ChIP-ChIP_M12_Human1.38478799
66HOXB4_20404135_ChIP-ChIP_EML_Mouse1.36802750
67SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.35462969
68IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.35278462
69STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.34446595
70IGF1R_20145208_ChIP-Seq_DFB_Human1.33680245
71* SPI1_23547873_ChIP-Seq_NB4_Human1.32945606
72WT1_19549856_ChIP-ChIP_CCG9911_Human1.32212041
73POU3F2_20337985_ChIP-ChIP_501MEL_Human1.31345780
74GATA1_22383799_ChIP-Seq_G1ME_Mouse1.29939424
75TCF4_18268006_ChIP-ChIP_LS174T_Human1.29487600
76ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.29271058
77RUNX1_22412390_ChIP-Seq_EML_Mouse1.26033767
78STAT4_19710469_ChIP-ChIP_TH1__Mouse1.25097000
79HIF1A_21447827_ChIP-Seq_MCF-7_Human1.24653985
80RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.24360971
81NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.23356012
82ESR2_21235772_ChIP-Seq_MCF-7_Human1.22420542
83* P300_27058665_Chip-Seq_ZR-75-30cells_Human1.19762886
84NCOR1_26117541_ChIP-Seq_K562_Human1.19442562
85* ELK3_25401928_ChIP-Seq_HUVEC_Human1.18010059
86CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.17271968
87FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.16211425
88ZNF217_24962896_ChIP-Seq_MCF-7_Human1.15769701
89FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse1.15332481
90OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.14368042
91FOXA2_19822575_ChIP-Seq_HepG2_Human1.14117518
92RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.13237920
93ELK1_22589737_ChIP-Seq_MCF10A_Human1.13006858
94ELF5_23300383_ChIP-Seq_T47D_Human1.12268731
95EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.11597496
96SMAD_19615063_ChIP-ChIP_OVARY_Human1.10128898
97TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.09640587
98VDR_24787735_ChIP-Seq_THP-1_Human1.09603427
99ERG_20887958_ChIP-Seq_HPC-7_Mouse1.09051047
100* FOXA1_21572438_ChIP-Seq_LNCaP_Human1.08366983
101FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.07440301
102SOX9_24532713_ChIP-Seq_HFSC_Mouse1.07319791
103SPI1_23127762_ChIP-Seq_K562_Human1.04975628
104AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.04661477
105SREBP1_19666523_ChIP-Seq_LIVER_Mouse1.04096931
106EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.03261443
107CJUN_26792858_Chip-Seq_BT549_Human1.02788423
108SCL_19346495_ChIP-Seq_HPC-7_Human1.02340495
109SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.02200793
110HTT_18923047_ChIP-ChIP_STHdh_Human1.01770361
111TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.01719864
112PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.99509470
113BRD4_27068464_Chip-Seq_AML-cells_Mouse0.99341502
114CREB1_15753290_ChIP-ChIP_HEK293T_Human0.98393007
115REST_19997604_ChIP-ChIP_NEURONS_Mouse0.98016177
116CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97945317
117GATA2_22383799_ChIP-Seq_G1ME_Mouse0.97775299
118SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.97378510
119CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.97211185
120CDX2_19796622_ChIP-Seq_MESCs_Mouse0.97058408
121CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.97028480
122GATA3_26560356_Chip-Seq_TH2_Human0.96983702
123PU_27001747_Chip-Seq_BMDM_Mouse0.96520986
124ESR1_20079471_ChIP-ChIP_T-47D_Human0.96270910
125ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.96075437
126HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.95699597
127RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.95599564
128ATF3_27146783_Chip-Seq_COLON_Human0.95160165
129NR3C1_23031785_ChIP-Seq_PC12_Mouse0.95049320
130ESR1_21235772_ChIP-Seq_MCF-7_Human0.94852628
131MYB_26560356_Chip-Seq_TH1_Human0.93978019
132* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.93759788
133FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse0.93734624
134* RACK7_27058665_Chip-Seq_MCF-7_Human0.93729614
135PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.93220047
136TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.92746367
137ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.92461213
138BRD4_25478319_ChIP-Seq_HGPS_Human0.91609342
139* TP63_23658742_ChIP-Seq_EP156T_Human0.91260960
140FLI1_20887958_ChIP-Seq_HPC-7_Mouse0.91000129
141P63_26484246_Chip-Seq_KERATINOCYTES_Human0.90906505
142PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.90532627
143FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.90141562
144PPARD_23208498_ChIP-Seq_MDA-MB-231_Human0.89908325
145AR_20517297_ChIP-Seq_VCAP_Human0.89585402
146RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.89300519
147FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89116350
148* FOXA1_27270436_Chip-Seq_PROSTATE_Human0.88540174
149* FOXA1_25329375_ChIP-Seq_VCAP_Human0.88540174
150PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse0.88322884
151SALL4_18804426_ChIP-ChIP_XEN_Mouse0.87396655
152DCP1A_22483619_ChIP-Seq_HELA_Human0.87294550
153GATA3_27048872_Chip-Seq_THYMUS_Human0.86711145
154ERG_20517297_ChIP-Seq_VCAP_Human0.84744853
155BCAT_22108803_ChIP-Seq_LS180_Human0.83371469

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.68262122
2MP0005360_urolithiasis4.22201784
3MP0005365_abnormal_bile_salt3.34742285
4MP0002877_abnormal_melanocyte_morpholog3.21801333
5MP0005085_abnormal_gallbladder_physiolo3.14884514
6MP0008875_abnormal_xenobiotic_pharmacok2.83745156
7MP0003195_calcinosis2.72733387
8MP0001666_abnormal_nutrient_absorption2.70054586
9MP0010234_abnormal_vibrissa_follicle2.64314715
10MP0010352_gastrointestinal_tract_polyps2.56438006
11MP0008438_abnormal_cutaneous_collagen2.49751519
12MP0003566_abnormal_cell_adhesion2.42295976
13MP0003183_abnormal_peptide_metabolism2.40945978
14MP0003806_abnormal_nucleotide_metabolis2.36349354
15MP0006054_spinal_hemorrhage2.29432033
16MP0002138_abnormal_hepatobiliary_system2.13957667
17MP0003868_abnormal_feces_composition2.06754586
18MP0010329_abnormal_lipoprotein_level1.93617128
19MP0005058_abnormal_lysosome_morphology1.91939382
20MP0010386_abnormal_urinary_bladder1.91870469
21MP0003724_increased_susceptibility_to1.87324073
22MP0003436_decreased_susceptibility_to1.86402906
23MP0003705_abnormal_hypodermis_morpholog1.77633893
24MP0008004_abnormal_stomach_pH1.77077688
25MP0002876_abnormal_thyroid_physiology1.69225441
26MP0009379_abnormal_foot_pigmentation1.67670007
27MP0005083_abnormal_biliary_tract1.66635810
28MP0003656_abnormal_erythrocyte_physiolo1.64593649
29MP0009643_abnormal_urine_homeostasis1.63011970
30MP0004272_abnormal_basement_membrane1.62637264
31MP0003300_gastrointestinal_ulcer1.62395359
32MP0005084_abnormal_gallbladder_morpholo1.59787525
33MP0005332_abnormal_amino_acid1.58924668
34MP0003091_abnormal_cell_migration1.58044874
35MP0001835_abnormal_antigen_presentation1.57438859
36MP0003866_abnormal_defecation1.57285927
37MP0005636_abnormal_mineral_homeostasis1.56867380
38MP0006276_abnormal_autonomic_nervous1.56838246
39MP0009785_altered_susceptibility_to1.54080837
40MP0003252_abnormal_bile_duct1.52152786
41MP0002796_impaired_skin_barrier1.52044938
42MP0005451_abnormal_body_composition1.51938705
43MP0005275_abnormal_skin_tensile1.49337087
44MP0009840_abnormal_foam_cell1.46765955
45MP0004947_skin_inflammation1.46390910
46MP0004043_abnormal_pH_regulation1.45068165
47MP0003186_abnormal_redox_activity1.43654478
48MP0003453_abnormal_keratinocyte_physiol1.43225437
49MP0001663_abnormal_digestive_system1.41342726
50MP0005023_abnormal_wound_healing1.40924301
51MP0002693_abnormal_pancreas_physiology1.40099398
52MP0000858_altered_metastatic_potential1.39868270
53MP0000013_abnormal_adipose_tissue1.39605590
54MP0005409_darkened_coat_color1.39247460
55MP0000538_abnormal_urinary_bladder1.37644175
56MP0005408_hypopigmentation1.35132200
57MP0002009_preneoplasia1.34243106
58MP0005666_abnormal_adipose_tissue1.32918355
59MP0005584_abnormal_enzyme/coenzyme_acti1.31586538
60MP0005220_abnormal_exocrine_pancreas1.29257934
61MP0000465_gastrointestinal_hemorrhage1.28694325
62MP0000609_abnormal_liver_physiology1.27184454
63MP0003303_peritoneal_inflammation1.26983412
64MP0001533_abnormal_skeleton_physiology1.26927082
65MP0004147_increased_porphyrin_level1.26528055
66MP0002118_abnormal_lipid_homeostasis1.25721848
67MP0002419_abnormal_innate_immunity1.24985718
68MP0002148_abnormal_hypersensitivity_rea1.24853998
69MP0004264_abnormal_extraembryonic_tissu1.23455725
70MP0008469_abnormal_protein_level1.21760352
71MP0005381_digestive/alimentary_phenotyp1.21339713
72MP0001845_abnormal_inflammatory_respons1.20719941
73MP0003828_pulmonary_edema1.20115929
74MP0005025_abnormal_response_to1.20086113
75MP0002909_abnormal_adrenal_gland1.19415146
76MP0005671_abnormal_response_to1.18553642
77MP0005000_abnormal_immune_tolerance1.17137407
78MP0010155_abnormal_intestine_physiology1.16710481
79MP0002735_abnormal_chemical_nociception1.16395171
80MP0005501_abnormal_skin_physiology1.16268729
81MP0005319_abnormal_enzyme/_coenzyme1.16023219
82MP0000604_amyloidosis1.15493731
83MP0009764_decreased_sensitivity_to1.14826561
84MP0001764_abnormal_homeostasis1.12612458
85MP0005464_abnormal_platelet_physiology1.11297137
86MP0005165_increased_susceptibility_to1.11050625
87MP0001664_abnormal_digestion1.09508805
88MP0002971_abnormal_brown_adipose1.08981524
89MP0004185_abnormal_adipocyte_glucose1.08307315
90MP0003950_abnormal_plasma_membrane1.07731582
91MP0002933_joint_inflammation1.07600143
92MP0006082_CNS_inflammation1.06141521
93MP0002078_abnormal_glucose_homeostasis1.05049093
94MP0001944_abnormal_pancreas_morphology1.04981173
95MP0005387_immune_system_phenotype1.04682107
96MP0001790_abnormal_immune_system1.04682107
97MP0001873_stomach_inflammation1.04475835
98MP0003191_abnormal_cellular_cholesterol1.03773641
99MP0009780_abnormal_chondrocyte_physiolo1.03629566
100MP0003763_abnormal_thymus_physiology1.03449512
101MP0001851_eye_inflammation1.03365562
102MP0005379_endocrine/exocrine_gland_phen1.02007972
103MP0001216_abnormal_epidermal_layer1.01354472
104MP0001800_abnormal_humoral_immune1.00714934
105MP0001756_abnormal_urination1.00283357
106MP0002452_abnormal_antigen_presenting0.99708385
107MP0001765_abnormal_ion_homeostasis0.99234864
108MP0005166_decreased_susceptibility_to0.99207464
109MP0006036_abnormal_mitochondrial_physio0.98718422
110MP0001542_abnormal_bone_strength0.97843335
111MP0000249_abnormal_blood_vessel0.96743866
112MP0002060_abnormal_skin_morphology0.96471244
113MP0001986_abnormal_taste_sensitivity0.95962041
114MP0008260_abnormal_autophagy0.94963278
115MP0002006_tumorigenesis0.93097452
116MP0001958_emphysema0.92207506
117MP0009697_abnormal_copulation0.91694159
118MP0001661_extended_life_span0.91581667
119MP0004782_abnormal_surfactant_physiolog0.91493381
120MP0000343_altered_response_to0.90390675
121MP0002723_abnormal_immune_serum0.90384481
122MP0002733_abnormal_thermal_nociception0.88443602
123MP0002132_abnormal_respiratory_system0.88374087
124MP0002420_abnormal_adaptive_immunity0.87353352
125MP0001819_abnormal_immune_cell0.87162160
126MP0004019_abnormal_vitamin_homeostasis0.86685290
127MP0005535_abnormal_body_temperature0.86587908
128MP0005375_adipose_tissue_phenotype0.86332843
129MP0009642_abnormal_blood_homeostasis0.86257098
130MP0002736_abnormal_nociception_after0.85202853
131MP0001881_abnormal_mammary_gland0.83683267
132MP0004883_abnormal_blood_vessel0.83528713
133MP0000490_abnormal_crypts_of0.83488468
134MP0002998_abnormal_bone_remodeling0.83252074
135MP0000462_abnormal_digestive_system0.82486676
136MP0003448_altered_tumor_morphology0.82037268
137MP0002166_altered_tumor_susceptibility0.81983204
138MP0001968_abnormal_touch/_nociception0.81857723
139MP0000477_abnormal_intestine_morphology0.80493145
140MP0002896_abnormal_bone_mineralization0.80349934
141MP0004270_analgesia0.80002778
142MP0005164_abnormal_response_to0.79415780
143MP0010678_abnormal_skin_adnexa0.79003942
144MP0005621_abnormal_cell_physiology0.78801525
145MP0009763_increased_sensitivity_to0.78745930
146MP0000685_abnormal_immune_system0.78405915
147MP0009333_abnormal_splenocyte_physiolog0.72449235
148MP0001879_abnormal_lymphatic_vessel0.72153719
149MP0003279_aneurysm0.71672340
150MP0001915_intracranial_hemorrhage0.68658381

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)4.09555668
2Increased mean platelet volume (HP:0011877)4.07808117
3Abnormal platelet volume (HP:0011876)3.77357166
4Menorrhagia (HP:0000132)3.75403440
5Abnormal tarsal ossification (HP:0008369)3.41999184
6Prolonged bleeding time (HP:0003010)3.39982375
7Vacuolated lymphocytes (HP:0001922)3.34166567
8Hypothermia (HP:0002045)3.15663734
9Beaking of vertebral bodies (HP:0004568)3.12013941
10Purpura (HP:0000979)3.00036820
11Conjugated hyperbilirubinemia (HP:0002908)2.95571697
12Gingival bleeding (HP:0000225)2.91582662
13Abnormality of glutamine family amino acid metabolism (HP:0010902)2.79970152
14Premature rupture of membranes (HP:0001788)2.78264456
15Fat malabsorption (HP:0002630)2.77684769
16Hypobetalipoproteinemia (HP:0003563)2.76111926
17Epistaxis (HP:0000421)2.73272989
18Abnormality of the intrinsic pathway (HP:0010989)2.73004201
19Irregular epiphyses (HP:0010582)2.72887016
20Polycythemia (HP:0001901)2.71915419
21Epiphyseal dysplasia (HP:0002656)2.66456974
22Mucopolysacchariduria (HP:0008155)2.65751716
23Urinary glycosaminoglycan excretion (HP:0003541)2.65751716
24Protrusio acetabuli (HP:0003179)2.64775940
25Abnormality of monocarboxylic acid metabolism (HP:0010996)2.64365417
26Abnormal platelet function (HP:0011869)2.64287440
27Impaired platelet aggregation (HP:0003540)2.64287440
28Arterial tortuosity (HP:0005116)2.64063737
29Osteolytic defects of the phalanges of the hand (HP:0009771)2.61676846
30Osteolytic defects of the hand bones (HP:0009699)2.61676846
31Intrahepatic cholestasis (HP:0001406)2.61058080
32Hyperlipoproteinemia (HP:0010980)2.60975652
33Xanthomatosis (HP:0000991)2.60743562
34Flat acetabular roof (HP:0003180)2.59428874
35Cupped ribs (HP:0000887)2.59288852
36Petechiae (HP:0000967)2.58647829
37Tetraparesis (HP:0002273)2.57972392
38Generalized aminoaciduria (HP:0002909)2.56961134
39Abnormal foot bone ossification (HP:0010675)2.56914178
40Complement deficiency (HP:0004431)2.55701993
41Abnormality of complement system (HP:0005339)2.55584883
42Hypoglycemic coma (HP:0001325)2.55428487
43Dysostosis multiplex (HP:0000943)2.54245662
44Abnormality of the common coagulation pathway (HP:0010990)2.54198157
45Vascular tortuosity (HP:0004948)2.50973245
46Acute encephalopathy (HP:0006846)2.50200611
47Recurrent gram-negative bacterial infections (HP:0005420)2.48911964
48Ketoacidosis (HP:0001993)2.48659465
49Ankyloglossia (HP:0010296)2.44784489
50Hepatic necrosis (HP:0002605)2.42944019
51Aortic dissection (HP:0002647)2.40966951
52Prolonged partial thromboplastin time (HP:0003645)2.38269063
53Systemic lupus erythematosus (HP:0002725)2.36377130
54Thoracolumbar scoliosis (HP:0002944)2.34845768
55Acute necrotizing encephalopathy (HP:0006965)2.33826756
56Mitral stenosis (HP:0001718)2.32837024
57Aortic aneurysm (HP:0004942)2.32697510
58Abnormality of mucopolysaccharide metabolism (HP:0011020)2.32172848
59Abnormality of polysaccharide metabolism (HP:0011012)2.32172848
60Abnormality of glycosaminoglycan metabolism (HP:0004371)2.32172848
61Eczematoid dermatitis (HP:0000976)2.32010892
62Protuberant abdomen (HP:0001538)2.31339827
63Abnormal mitochondria in muscle tissue (HP:0008316)2.31116395
64Poikilocytosis (HP:0004447)2.30937388
65Ketosis (HP:0001946)2.30161495
66Hemorrhage of the eye (HP:0011885)2.28077400
67Termporal pattern (HP:0011008)2.25488711
68Insidious onset (HP:0003587)2.25488711
69Irregular vertebral endplates (HP:0003301)2.24990341
70Abnormality of the lumbar spine (HP:0100712)2.24491066
71Hepatocellular necrosis (HP:0001404)2.24177539
72Reduced antithrombin III activity (HP:0001976)2.20709374
73Vertebral compression fractures (HP:0002953)2.19559189
74Glomerulonephritis (HP:0000099)2.16285042
75Abnormality of urine glucose concentration (HP:0011016)2.15882722
76Glycosuria (HP:0003076)2.15882722
77Papillary thyroid carcinoma (HP:0002895)2.14640132
78Abnormality of purine metabolism (HP:0004352)2.13775842
79Symptomatic seizures (HP:0011145)2.13546848
80Neuroendocrine neoplasm (HP:0100634)2.11191365
81Spontaneous hematomas (HP:0007420)2.10832982
82Progressive macrocephaly (HP:0004481)2.09536708
83Ileus (HP:0002595)2.09340246
84Chronic diarrhea (HP:0002028)2.09243433
85Axonal loss (HP:0003447)2.08764330
86Recurrent bacterial skin infections (HP:0005406)2.08257729
87Pheochromocytoma (HP:0002666)2.07559487
88Hyperphosphaturia (HP:0003109)2.07104217
89Steatorrhea (HP:0002570)2.06857311
90Cardiovascular calcification (HP:0011915)2.06323857
91Hydroxyprolinuria (HP:0003080)2.06027532
92Abnormality of proline metabolism (HP:0010907)2.06027532
93Mitochondrial inheritance (HP:0001427)2.05810299
94Deep venous thrombosis (HP:0002625)2.05686605
95Dilatation of the ascending aorta (HP:0005111)2.05374297
96Abnormality of oral frenula (HP:0000190)2.05359706
97Abnormality of the level of lipoprotein cholesterol (HP:0010979)2.04579940
98Abdominal distention (HP:0003270)2.03748115
99Recurrent abscess formation (HP:0002722)2.03256547
100Abnormality of the vertebral endplates (HP:0005106)2.02575841
101Epidermoid cyst (HP:0200040)1.99820479
102Cerebral edema (HP:0002181)1.98956625
103Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.97476910
104Hyperactive renin-angiotensin system (HP:0000841)1.97279724
105Hyperbilirubinemia (HP:0002904)1.97017341
106Metaphyseal dysplasia (HP:0100255)1.96801394
107Small epiphyses (HP:0010585)1.95606069
108Right ventricular cardiomyopathy (HP:0011663)1.95429666
109Conjunctival hamartoma (HP:0100780)1.95235192
110Acanthocytosis (HP:0001927)1.95196009
111Delayed epiphyseal ossification (HP:0002663)1.95079160
112Exocrine pancreatic insufficiency (HP:0001738)1.94680497
113Myocardial infarction (HP:0001658)1.93921223
114Vascular calcification (HP:0004934)1.93153747
115Pancreatitis (HP:0001733)1.92785452
116Irritability (HP:0000737)1.92457794
117Primitive reflexes (palmomental, snout, glabellar) (HP:0002476)1.90363346
118Abnormality of the Achilles tendon (HP:0005109)1.90132550
119Disinhibition (HP:0000734)1.89011472
120Autoamputation (HP:0001218)1.88992776
121Hyperammonemia (HP:0001987)1.88855867
122Abnormality of fatty-acid metabolism (HP:0004359)1.88844784
123Hypoglycemic seizures (HP:0002173)1.87923352
124Back pain (HP:0003418)1.87754311
125Abnormal cartilage morphology (HP:0002763)1.87254636
126Hypotension (HP:0002615)1.84389095
127Elevated circulating parathyroid hormone (PTH) level (HP:0003165)1.83840669
128Growth hormone excess (HP:0000845)1.83688065
129Agitation (HP:0000713)1.83020040
130Gout (HP:0001997)1.81933178
131Thin bony cortex (HP:0002753)1.80837204
132Flattened epiphyses (HP:0003071)1.80206583
133Joint swelling (HP:0001386)1.79971697
134Flat capital femoral epiphysis (HP:0003370)1.79762092
135Joint hemorrhage (HP:0005261)1.79332708
136Renal tubular acidosis (HP:0001947)1.79000451
137Hyperparathyroidism (HP:0000843)1.77815384
138Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.77585413
139Abnormal protein N-linked glycosylation (HP:0012347)1.77585413
140Abnormal protein glycosylation (HP:0012346)1.77585413
141Abnormal glycosylation (HP:0012345)1.77585413
142Nephritis (HP:0000123)1.77220315
143Cholecystitis (HP:0001082)1.76533567
144Abnormal gallbladder physiology (HP:0012438)1.76533567
145Abnormal epiphyseal ossification (HP:0010656)1.76096313
146Cerebral hemorrhage (HP:0001342)1.75646283
147Enlarged epiphyses (HP:0010580)1.75539127
148Late onset (HP:0003584)1.74964033
149Papilledema (HP:0001085)1.74712095
150Metaphyseal irregularity (HP:0003025)1.74584413
151Nausea (HP:0002018)1.74499185
152Abnormality of macrophages (HP:0004311)1.74109941
153Arthropathy (HP:0003040)1.74052196
154Wormian bones (HP:0002645)1.73636712
155Hypolipoproteinemia (HP:0010981)1.73147131
156Increased CSF lactate (HP:0002490)1.73044162
157Alkalosis (HP:0001948)1.72536201
158Malnutrition (HP:0004395)1.72402605
159Curly hair (HP:0002212)1.71502937
160Orthostatic hypotension (HP:0001278)1.71470365
161Asymmetry of the thorax (HP:0001555)1.71271942
162Gastrointestinal stroma tumor (HP:0100723)1.69980084
163Coarse hair (HP:0002208)1.69844126
164Bone pain (HP:0002653)1.69472193
165Fatigue (HP:0012378)1.66821972
166Interstitial pulmonary disease (HP:0006530)1.65179629
167Glucose intolerance (HP:0000833)1.64657223
168Abnormality of carpal bone ossification (HP:0006257)1.64657105
169Chondrocalcinosis (HP:0000934)1.62676217
170Mildly elevated creatine phosphokinase (HP:0008180)1.62483412
171Abnormality of the gastric mucosa (HP:0004295)1.61475521
172Aneurysm (HP:0002617)1.61261985
173Abnormal glucose tolerance (HP:0001952)1.61105463
174Hypercholesterolemia (HP:0003124)1.60983828
175Male infertility (HP:0003251)1.60547256
176Multiple lipomas (HP:0001012)1.59264264
177Distal lower limb amyotrophy (HP:0008944)1.59159273
178Abnormal delivery (HP:0001787)1.58901398
179Atrophic scars (HP:0001075)1.58147970

Predicted kinase interactions (KEA)

RankGene SetZ-score
1FRK3.44168334
2LMTK23.07661531
3BMPR22.76631589
4MST42.74066328
5ARAF2.61442566
6MAP3K122.58047801
7LIMK12.57547261
8ERN12.44607691
9NME22.37005834
10PIM22.34534480
11PRPF4B2.31934555
12TESK12.29633921
13EIF2AK32.24015440
14MYLK2.19385038
15SCYL22.00909361
16EPHA21.99056962
17TAOK31.92914877
18IRAK41.92307281
19NME11.90787836
20ACVR1B1.86243097
21MAP3K21.76142743
22RIPK11.71686569
23SIK31.66234345
24MST1R1.63883381
25RIPK41.62213241
26TRIB31.55570112
27PDGFRA1.50914244
28CASK1.43818613
29BLK1.43378017
30KSR21.41654326
31GRK51.38785307
32JAK11.34842184
33BCKDK1.33631489
34TYK21.31475672
35TRPM71.28634443
36CSNK1G31.28298606
37MAP2K71.27791691
38TBK11.22560389
39CDK61.21148464
40CSNK1G21.20068855
41STK31.17945779
42GRK61.17266680
43EIF2AK11.17078096
44TESK21.15181313
45FLT31.11307005
46SYK1.10376173
47EEF2K1.09995860
48ABL21.09307988
49NTRK11.08500377
50TEC1.08088262
51PKN21.07998516
52DYRK21.07445445
53ILK1.07039414
54EPHB11.06334351
55BCR1.05874096
56MAP3K141.05640888
57MAP2K11.05394543
58PRKG21.04621881
59MAP3K61.04596581
60PAK41.03345987
61NEK91.02540104
62ICK1.01650099
63ERBB31.01219462
64BMX1.01092109
65TGFBR20.99635758
66MET0.99022506
67OXSR10.98632342
68MARK10.97635520
69MINK10.97615534
70NEK10.93942941
71PLK20.93883538
72KIT0.93540166
73CAMKK20.92069672
74CSNK1A1L0.92040314
75KSR10.91428625
76MAP3K40.89490608
77EPHA30.87227542
78MATK0.84446302
79MAP4K10.83794146
80PIK3CG0.83666057
81PBK0.83313686
82MAP3K100.81740355
83INSRR0.81236872
84MAP3K10.81014000
85BRAF0.80855368
86STK240.80135097
87LATS20.78444191
88BMPR1B0.78283476
89PAK20.77956265
90YES10.75957159
91ERBB40.75743080
92PTK20.74518341
93CSNK1G10.74012675
94MAP3K110.73984277
95MAPK110.73878595
96IRAK30.72754272
97MAP3K130.72132533
98TTN0.71293662
99WNK40.70249630
100CLK10.69857774
101MAP3K90.69838148
102FER0.69514062
103ZAP700.68664069
104PIK3CA0.68241243
105JAK30.67224831
106MAP2K20.67051958
107FGFR30.66122136
108PRKCE0.65069711
109MAP3K30.64955322
110CSK0.64208661
111PTK60.64085447
112LYN0.63396136
113LRRK20.62504027
114MAPK40.61732137
115PDGFRB0.61520280
116JAK20.60120447
117MAPKAPK30.59756503
118CSF1R0.59644987
119RET0.56975542
120PDPK10.56210779
121TAOK20.54872946
122MAP2K30.54209709
123MAP2K40.53011848
124FGFR40.52935220
125CDK190.52691377
126FGR0.52301999
127STK160.51826905
128ADRBK20.51821913
129BTK0.51537306
130MAP3K80.50539002
131PDK10.50052633
132BRSK20.49822249
133RAF10.49819204
134RPS6KA40.48923675
135DDR20.47813291
136PRKCI0.47695749
137CCNB10.47022083
138ITK0.45031812
139SIK10.44834658
140STK390.44754925
141PRKCD0.44116275
142STK100.43782047
143CDK140.43492022
144DMPK0.42438604
145IRAK10.42083627
146MAPKAPK20.39221233
147MOS0.35012191
148CDC42BPA0.32971427
149HCK0.32004174
150CDK120.31292508

Predicted pathways (KEGG)

RankGene SetZ-score
1Sulfur metabolism_Homo sapiens_hsa009204.63978996
2Protein export_Homo sapiens_hsa030603.66019764
3Butirosin and neomycin biosynthesis_Homo sapiens_hsa005243.28804272
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.94236201
5Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.40183967
6Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.26274851
7Folate biosynthesis_Homo sapiens_hsa007902.20156293
8Vibrio cholerae infection_Homo sapiens_hsa051102.18433289
9Pentose and glucuronate interconversions_Homo sapiens_hsa000402.14096980
10Oxidative phosphorylation_Homo sapiens_hsa001901.91027018
11Caffeine metabolism_Homo sapiens_hsa002321.89150520
12Primary bile acid biosynthesis_Homo sapiens_hsa001201.85209977
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.81891599
14Cyanoamino acid metabolism_Homo sapiens_hsa004601.80454827
15Histidine metabolism_Homo sapiens_hsa003401.76894276
16Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.73239570
17Tryptophan metabolism_Homo sapiens_hsa003801.72198207
18Butanoate metabolism_Homo sapiens_hsa006501.71402452
19Steroid biosynthesis_Homo sapiens_hsa001001.68309156
20Fat digestion and absorption_Homo sapiens_hsa049751.67773439
21N-Glycan biosynthesis_Homo sapiens_hsa005101.66668945
22Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.57705873
23Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.54898178
24Collecting duct acid secretion_Homo sapiens_hsa049661.54504373
25Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.53852835
26Peroxisome_Homo sapiens_hsa041461.51290130
27Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.45894261
28Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.38867187
29Platelet activation_Homo sapiens_hsa046111.38826483
30Phagosome_Homo sapiens_hsa041451.37429704
31Parkinsons disease_Homo sapiens_hsa050121.36868180
32Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.34937744
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.31110780
34Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.30290898
35Fructose and mannose metabolism_Homo sapiens_hsa000511.29990253
36Pancreatic cancer_Homo sapiens_hsa052121.28939809
37Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.27702984
38Bacterial invasion of epithelial cells_Homo sapiens_hsa051001.21281612
39Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.20353035
40Fatty acid degradation_Homo sapiens_hsa000711.20059088
41Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.17659945
42Chronic myeloid leukemia_Homo sapiens_hsa052201.15397969
43Starch and sucrose metabolism_Homo sapiens_hsa005001.14783055
44Fatty acid elongation_Homo sapiens_hsa000621.14634767
45Propanoate metabolism_Homo sapiens_hsa006401.11246660
46Pyruvate metabolism_Homo sapiens_hsa006201.11138578
47Alzheimers disease_Homo sapiens_hsa050101.11116096
48SNARE interactions in vesicular transport_Homo sapiens_hsa041301.10253798
49Lysosome_Homo sapiens_hsa041421.06535989
50Selenocompound metabolism_Homo sapiens_hsa004501.03111699
51Drug metabolism - other enzymes_Homo sapiens_hsa009831.02736187
52Renal cell carcinoma_Homo sapiens_hsa052111.01633007
53Leukocyte transendothelial migration_Homo sapiens_hsa046701.01607471
54Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.01253144
55Glutathione metabolism_Homo sapiens_hsa004800.99783250
56B cell receptor signaling pathway_Homo sapiens_hsa046620.99208344
57AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.98624657
58beta-Alanine metabolism_Homo sapiens_hsa004100.97766915
59Renin-angiotensin system_Homo sapiens_hsa046140.96770753
60Pertussis_Homo sapiens_hsa051330.96455514
61Arginine biosynthesis_Homo sapiens_hsa002200.93862560
62PPAR signaling pathway_Homo sapiens_hsa033200.93562715
63Other glycan degradation_Homo sapiens_hsa005110.93230819
64Chemical carcinogenesis_Homo sapiens_hsa052040.89696505
65Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89633513
66Proteasome_Homo sapiens_hsa030500.89180159
67Complement and coagulation cascades_Homo sapiens_hsa046100.88328151
68ECM-receptor interaction_Homo sapiens_hsa045120.86159272
69Focal adhesion_Homo sapiens_hsa045100.85765566
70Vitamin digestion and absorption_Homo sapiens_hsa049770.84448324
71Non-small cell lung cancer_Homo sapiens_hsa052230.83355712
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.82480659
73Mineral absorption_Homo sapiens_hsa049780.82334839
74Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.82201814
75Amoebiasis_Homo sapiens_hsa051460.80984448
76Staphylococcus aureus infection_Homo sapiens_hsa051500.79738900
77Acute myeloid leukemia_Homo sapiens_hsa052210.79484154
78Steroid hormone biosynthesis_Homo sapiens_hsa001400.79110937
79Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.78411676
80Legionellosis_Homo sapiens_hsa051340.77362006
81Phenylalanine metabolism_Homo sapiens_hsa003600.74908801
82Rheumatoid arthritis_Homo sapiens_hsa053230.73177209
83Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.72720617
84Bile secretion_Homo sapiens_hsa049760.72405388
85Shigellosis_Homo sapiens_hsa051310.72400552
86Prion diseases_Homo sapiens_hsa050200.71559969
87Fatty acid metabolism_Homo sapiens_hsa012120.69669746
88Tuberculosis_Homo sapiens_hsa051520.65775320
89Hematopoietic cell lineage_Homo sapiens_hsa046400.65223078
90Insulin resistance_Homo sapiens_hsa049310.64918182
91Small cell lung cancer_Homo sapiens_hsa052220.63953545
92Tyrosine metabolism_Homo sapiens_hsa003500.62426720
93Adipocytokine signaling pathway_Homo sapiens_hsa049200.59989402
94Endocytosis_Homo sapiens_hsa041440.59764089
95Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.59666210
96Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.59226609
97Toxoplasmosis_Homo sapiens_hsa051450.58491700
98Adherens junction_Homo sapiens_hsa045200.57983009
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.56970854
100Biosynthesis of amino acids_Homo sapiens_hsa012300.56960281
101VEGF signaling pathway_Homo sapiens_hsa043700.56948597
1022-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.56846378
103Proteoglycans in cancer_Homo sapiens_hsa052050.56747124
104Arachidonic acid metabolism_Homo sapiens_hsa005900.56038654
105* Metabolic pathways_Homo sapiens_hsa011000.55620175
106Insulin signaling pathway_Homo sapiens_hsa049100.54141294
107Central carbon metabolism in cancer_Homo sapiens_hsa052300.54021342
108Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.53971413
109Endometrial cancer_Homo sapiens_hsa052130.53590411
110Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.52698594
111Sphingolipid metabolism_Homo sapiens_hsa006000.51872288
112Leishmaniasis_Homo sapiens_hsa051400.51581213
113Fatty acid biosynthesis_Homo sapiens_hsa000610.51120947
114Glycerolipid metabolism_Homo sapiens_hsa005610.49615366
115Phosphatidylinositol signaling system_Homo sapiens_hsa040700.49556280
116Synaptic vesicle cycle_Homo sapiens_hsa047210.49520843
117Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.49495797
118TNF signaling pathway_Homo sapiens_hsa046680.49012857
119Prolactin signaling pathway_Homo sapiens_hsa049170.48531972
120Pentose phosphate pathway_Homo sapiens_hsa000300.47889740
121Glycosaminoglycan degradation_Homo sapiens_hsa005310.47882252
122mTOR signaling pathway_Homo sapiens_hsa041500.47674200
123Galactose metabolism_Homo sapiens_hsa000520.47613939
124Pancreatic secretion_Homo sapiens_hsa049720.46912058
125Glioma_Homo sapiens_hsa052140.45951995
126Huntingtons disease_Homo sapiens_hsa050160.45267960
127Hepatitis B_Homo sapiens_hsa051610.44792742
128Nitrogen metabolism_Homo sapiens_hsa009100.43524387
129Protein digestion and absorption_Homo sapiens_hsa049740.43488525
130Choline metabolism in cancer_Homo sapiens_hsa052310.43365196
131Salmonella infection_Homo sapiens_hsa051320.42779573
132Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.42495894
133Retinol metabolism_Homo sapiens_hsa008300.41023749
134Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.39885776
135Hepatitis C_Homo sapiens_hsa051600.38221255
136Sulfur relay system_Homo sapiens_hsa041220.37184135
137Thyroid hormone synthesis_Homo sapiens_hsa049180.36090159
138Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.34993205
139Thyroid cancer_Homo sapiens_hsa052160.34953744
140Arginine and proline metabolism_Homo sapiens_hsa003300.34404777
141Carbon metabolism_Homo sapiens_hsa012000.33287808
142Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.32774868
143Carbohydrate digestion and absorption_Homo sapiens_hsa049730.31551218
144Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.30919498

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