CMTR1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.83860866
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.83860866
3antigen processing and presentation of endogenous antigen (GO:0019883)5.64666696
4positive regulation of gamma-delta T cell activation (GO:0046645)4.93937137
5negative regulation of erythrocyte differentiation (GO:0045647)4.53524170
6regulation of ARF protein signal transduction (GO:0032012)4.32331575
7sodium ion export (GO:0071436)4.20016786
8synaptic vesicle maturation (GO:0016188)4.09844164
9negative regulation of cell killing (GO:0031342)4.06283431
10negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.06283431
11regulation of gamma-delta T cell differentiation (GO:0045586)3.65577055
12positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.58540486
13cellular response to zinc ion (GO:0071294)3.56196463
14locomotory exploration behavior (GO:0035641)3.52876173
15regulation of interleukin-12 biosynthetic process (GO:0045075)3.49447452
16response to muramyl dipeptide (GO:0032495)3.47739850
17regulation of gamma-delta T cell activation (GO:0046643)3.45433877
18regulation of short-term neuronal synaptic plasticity (GO:0048172)3.38697258
19protein localization to endosome (GO:0036010)3.36543537
20positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.35171753
21synaptic vesicle docking involved in exocytosis (GO:0016081)3.30536804
22negative regulation of amyloid precursor protein catabolic process (GO:1902992)3.29238192
23negative thymic T cell selection (GO:0045060)3.25874858
24synaptic vesicle exocytosis (GO:0016079)3.17703130
25response to peptidoglycan (GO:0032494)3.17348381
26nuclear pore complex assembly (GO:0051292)3.16241862
27JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)3.10881546
28negative T cell selection (GO:0043383)3.10869492
29cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.09994509
30regulation of histone H3-K27 methylation (GO:0061085)3.09611582
313-UTR-mediated mRNA stabilization (GO:0070935)3.08003465
32natural killer cell differentiation (GO:0001779)3.04712380
33interferon-gamma-mediated signaling pathway (GO:0060333)3.02706232
34cellular response to virus (GO:0098586)3.01994611
35positive regulation of interferon-alpha production (GO:0032727)2.98444751
36germinal center formation (GO:0002467)2.97501988
37detection of other organism (GO:0098543)2.96264017
38response to type I interferon (GO:0034340)2.94519829
39dicarboxylic acid biosynthetic process (GO:0043650)2.94344703
40modulation by symbiont of host cellular process (GO:0044068)2.93283882
41positive regulation of histone deacetylation (GO:0031065)2.92926171
42cellular potassium ion homeostasis (GO:0030007)2.92654295
43regulation of defense response to virus by virus (GO:0050690)2.92406261
44detection of bacterium (GO:0016045)2.91843033
45type I interferon signaling pathway (GO:0060337)2.90793140
46cellular response to type I interferon (GO:0071357)2.90793140
47antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.90478767
48histone H3-K36 demethylation (GO:0070544)2.90132162
49mannose metabolic process (GO:0006013)2.90002518
50positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.89609766
51cellular response to interferon-alpha (GO:0035457)2.89397493
52positive thymic T cell selection (GO:0045059)2.86927263
53response to laminar fluid shear stress (GO:0034616)2.86448607
54regulation of type I interferon-mediated signaling pathway (GO:0060338)2.85927028
55lipopolysaccharide-mediated signaling pathway (GO:0031663)2.84130036
56B cell receptor signaling pathway (GO:0050853)2.83873506
57regulation of nucleobase-containing compound transport (GO:0032239)2.83522064
58NIK/NF-kappaB signaling (GO:0038061)2.81967268
59peptidyl-lysine dimethylation (GO:0018027)2.81199962
60regulation of B cell receptor signaling pathway (GO:0050855)2.80566639
61regulation of ARF GTPase activity (GO:0032312)2.80211287
62activation of protein kinase A activity (GO:0034199)2.79297764
63regulation of interferon-alpha production (GO:0032647)2.78734924
64oxaloacetate metabolic process (GO:0006107)2.78068023
65alanine transport (GO:0032328)2.77474526
66pre-miRNA processing (GO:0031054)2.76332597
67cell communication by electrical coupling (GO:0010644)2.74700566
68regulation of translational termination (GO:0006449)2.74657034
69proline transport (GO:0015824)2.73845537
70regulation of necroptotic process (GO:0060544)2.73104670
71positive regulation of B cell differentiation (GO:0045579)2.72874323
72response to host defenses (GO:0052200)2.72860706
73response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.72860706
74response to host (GO:0075136)2.72860706
75regulation of RNA export from nucleus (GO:0046831)2.72432394
76positive regulation of Cdc42 GTPase activity (GO:0043089)2.72423191
77embryonic process involved in female pregnancy (GO:0060136)2.71785569
78response to interferon-alpha (GO:0035455)2.71719024
79antigen processing and presentation via MHC class Ib (GO:0002475)2.69474852
80pinocytosis (GO:0006907)2.68055294
81thymic T cell selection (GO:0045061)2.65826819
82regulation of interferon-beta biosynthetic process (GO:0045357)2.65069692
83spliceosomal tri-snRNP complex assembly (GO:0000244)2.65035294
84T cell selection (GO:0045058)2.64747313
85signal complex assembly (GO:0007172)2.63666349
86Golgi transport vesicle coating (GO:0048200)2.61972246
87COPI coating of Golgi vesicle (GO:0048205)2.61972246
88retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.60848868
89regulation of NFAT protein import into nucleus (GO:0051532)2.60541108
90regulation of early endosome to late endosome transport (GO:2000641)2.59849197
91chaperone mediated protein folding requiring cofactor (GO:0051085)2.56913572
92positive T cell selection (GO:0043368)2.56868319
93positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.55741096
94negative regulation of interleukin-12 production (GO:0032695)2.55632827
95glutamate secretion (GO:0014047)2.53132981
96focal adhesion assembly (GO:0048041)2.52043326
97cell-substrate adherens junction assembly (GO:0007045)2.52043326
98detection of external biotic stimulus (GO:0098581)2.51818375
99response to host immune response (GO:0052572)2.51012357
100response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.51012357
101regulation of B cell differentiation (GO:0045577)2.50822043
102substrate-dependent cell migration (GO:0006929)2.49435540
103macrophage activation involved in immune response (GO:0002281)2.49263699
104modulation by virus of host process (GO:0019054)2.49240711
105response to interleukin-15 (GO:0070672)2.48803071
106myeloid dendritic cell differentiation (GO:0043011)2.48368457
107negative regulation of toll-like receptor signaling pathway (GO:0034122)2.48240304
108modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.47795945
109positive regulation by organism of defense response of other organism involved in symbiotic interact2.47795945
110modulation by symbiont of host immune response (GO:0052553)2.47795945
111positive regulation by symbiont of host defense response (GO:0052509)2.47795945
112modulation by symbiont of host defense response (GO:0052031)2.47795945
113modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.47795945
114negative regulation of viral release from host cell (GO:1902187)2.47534265
115negative regulation of necroptotic process (GO:0060546)2.47050352
116neurotransmitter secretion (GO:0007269)2.46803188
117positive regulation of natural killer cell differentiation (GO:0032825)2.46166595
118mitotic chromosome condensation (GO:0007076)2.45107331
119detection of molecule of bacterial origin (GO:0032490)2.45070544
120regulation of synaptic vesicle exocytosis (GO:2000300)2.43790993
121pore complex assembly (GO:0046931)2.42873498
122regulation of glucose import in response to insulin stimulus (GO:2001273)2.42411094
123RNA stabilization (GO:0043489)2.42007725
124mRNA stabilization (GO:0048255)2.42007725
125positive regulation of type 2 immune response (GO:0002830)2.41807947
126nuclear pore organization (GO:0006999)2.40375005
127epithelial cell differentiation involved in prostate gland development (GO:0060742)2.40099778
128cellular sodium ion homeostasis (GO:0006883)2.40096862
129adherens junction assembly (GO:0034333)2.39748407
130leukocyte aggregation (GO:0070486)2.39472752
131stress fiber assembly (GO:0043149)2.39316983
132immunoglobulin mediated immune response (GO:0016064)2.38934357
133potassium ion import (GO:0010107)2.37896130
134negative regulation of T cell mediated immunity (GO:0002710)2.37545306
135activation of MAPKKK activity (GO:0000185)2.36934825
136cerebellar Purkinje cell layer development (GO:0021680)2.35549363
137histone H3-K9 demethylation (GO:0033169)2.33932857
138histone lysine demethylation (GO:0070076)2.33000017
139regulation of T-helper 2 cell differentiation (GO:0045628)2.32536110
140cellular response to interferon-gamma (GO:0071346)2.31112348
141regulation of cellular amide metabolic process (GO:0034248)2.30731714
142regulation of synapse structural plasticity (GO:0051823)2.29854770
143regulation of fatty acid beta-oxidation (GO:0031998)2.29749213
144regulation of clathrin-mediated endocytosis (GO:2000369)2.29733840
145positive regulation of type I interferon-mediated signaling pathway (GO:0060340)2.28937462
146G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)2.28351976
147positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)2.27358027
148macroautophagy (GO:0016236)2.26522888
149regulation of response to interferon-gamma (GO:0060330)2.26022414
150positive regulation of nitric-oxide synthase activity (GO:0051000)2.25782998
151positive regulation of vesicle fusion (GO:0031340)2.25253959
152negative regulation of cell size (GO:0045792)2.24041580
153T cell migration (GO:0072678)2.24039324
154growth hormone receptor signaling pathway (GO:0060396)2.22548373

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1IRF8_22096565_ChIP-ChIP_GC-B_Human4.57931155
2EGR1_19374776_ChIP-ChIP_THP-1_Human4.02317395
3NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.49458887
4STAT6_20620947_ChIP-Seq_CD4_POS_T_Human3.35233895
5MYC_22102868_ChIP-Seq_BL_Human3.31009650
6IRF8_21731497_ChIP-ChIP_J774_Mouse2.82570731
7IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.67053570
8VDR_21846776_ChIP-Seq_THP-1_Human2.50280110
9KDM2B_26808549_Chip-Seq_DND41_Human2.43255164
10FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.38930383
11MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.36847565
12TCF7_22412390_ChIP-Seq_EML_Mouse2.34012522
13KDM2B_26808549_Chip-Seq_SUP-B15_Human2.31895151
14THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.19694869
15KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.17203550
16MAF_26560356_Chip-Seq_TH1_Human2.16269188
17IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.15347502
18E2F7_22180533_ChIP-Seq_HELA_Human2.14776545
19TP63_17297297_ChIP-ChIP_HaCaT_Human2.13788981
20IRF8_27001747_Chip-Seq_BMDM_Mouse2.08158889
21E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human2.07253050
22KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.00669450
23SPI1_23127762_ChIP-Seq_K562_Human1.99861499
24NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.97360856
25UTX_26944678_Chip-Seq_JUKART_Human1.92591061
26NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.89622243
27LXR_22292898_ChIP-Seq_THP-1_Human1.89175927
28EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.85582916
29SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.82618062
30VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.80306289
31STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.80287958
32GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.79405411
33GATA1_19941827_ChIP-Seq_MEL_Mouse1.75513607
34IKZF1_21737484_ChIP-ChIP_HCT116_Human1.74336383
35FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.74205553
36FOXM1_23109430_ChIP-Seq_U2OS_Human1.71641768
37GATA1_22025678_ChIP-Seq_K562_Human1.68300158
38MYB_21317192_ChIP-Seq_ERMYB_Mouse1.68173340
39BRD4_27068464_Chip-Seq_AML-cells_Mouse1.63203224
40CIITA_25753668_ChIP-Seq_RAJI_Human1.60995636
41EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.59793241
42ELK3_25401928_ChIP-Seq_HUVEC_Human1.58991846
43RUNX_20019798_ChIP-Seq_JUKART_Human1.58097237
44RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.55628967
45VDR_24763502_ChIP-Seq_THP-1_Human1.55236528
46TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.54778651
47DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.53897591
48ZFP281_18757296_ChIP-ChIP_E14_Mouse1.52583296
49MYB_26560356_Chip-Seq_TH1_Human1.52144008
50KDM2B_26808549_Chip-Seq_K562_Human1.52131418
51EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.50951212
52MYB_26560356_Chip-Seq_TH2_Human1.49656989
53KDM2B_26808549_Chip-Seq_JURKAT_Human1.49621989
54ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.49217096
55STAT4_19710469_ChIP-ChIP_TH1__Mouse1.49198934
56RARG_19884340_ChIP-ChIP_MEFs_Mouse1.46630595
57SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.46154353
58MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.45339117
59BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.45096430
60STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.42369350
61RARB_27405468_Chip-Seq_BRAIN_Mouse1.42317861
62GATA3_27048872_Chip-Seq_THYMUS_Human1.40363741
63DNAJC2_21179169_ChIP-ChIP_NT2_Human1.36733239
64GATA1_19941826_ChIP-Seq_K562_Human1.36336154
65KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.35517183
66ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.35090883
67MAF_26560356_Chip-Seq_TH2_Human1.34669881
68GATA1_22383799_ChIP-Seq_G1ME_Mouse1.33252101
69RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.31269521
70DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.30849846
71PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.30140886
72CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.25109623
73TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.22672674
74TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.21833094
75SPI1_23547873_ChIP-Seq_NB4_Human1.21275314
76MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.21120743
77TFAP2A_17053090_ChIP-ChIP_MCF-7_Human1.18295681
78CLOCK_20551151_ChIP-Seq_293T_Human1.17905535
79RUNX1_22412390_ChIP-Seq_EML_Mouse1.17792557
80PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.17287100
81ZFP281_27345836_Chip-Seq_ESCs_Mouse1.16867986
82SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.16833361
83SCL_19346495_ChIP-Seq_HPC-7_Human1.16308990
84TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.16298047
85P300_27058665_Chip-Seq_ZR-75-30cells_Human1.15780058
86SMC4_20622854_ChIP-Seq_HELA_Human1.15616642
87ZNF263_19887448_ChIP-Seq_K562_Human1.14954553
88ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.14754155
89PPARA_22158963_ChIP-Seq_LIVER_Mouse1.13777312
90DROSHA_22980978_ChIP-Seq_HELA_Human1.12908014
91NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.11908888
92FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.11582312
93GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.10826051
94BP1_19119308_ChIP-ChIP_Hs578T_Human1.10327900
95BCL6_27268052_Chip-Seq_Bcells_Human1.09872700
96GATA2_22383799_ChIP-Seq_G1ME_Mouse1.08959428
97P68_20966046_ChIP-Seq_HELA_Human1.08907459
98HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.08584474
99TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.07427426
100UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.07118755
101TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06835576
102TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse1.06569486
103WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.06568830
104KLF4_18555785_ChIP-Seq_MESCs_Mouse1.06365738
105NCOR1_26117541_ChIP-Seq_K562_Human1.05906964
106CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.04892946
107SA1_27219007_Chip-Seq_ERYTHROID_Human1.04435635
108CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.04367845
109PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.04258525
110KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.02868568
111MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.02767316
112ELF1_20517297_ChIP-Seq_JURKAT_Human1.02747590
113RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.02394971
114CREB1_26743006_Chip-Seq_LNCaP_Human1.02269032
115RACK7_27058665_Chip-Seq_MCF-7_Human1.02216959
116SOX11_23321250_ChIP-ChIP_Z138-A519-JVM2_Human1.01870592
117RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.01742904
118KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.99863877
119PU.1_20513432_ChIP-Seq_Bcells_Mouse0.99533525
120ESR2_21235772_ChIP-Seq_MCF-7_Human0.98931921
121RXR_22158963_ChIP-Seq_LIVER_Mouse0.98107365
122STAT6_21828071_ChIP-Seq_BEAS2B_Human0.97988571
123ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.93366530
124BCOR_27268052_Chip-Seq_Bcells_Human0.93018924
125PU_27001747_Chip-Seq_BMDM_Mouse0.93018307
126GATA2_19941826_ChIP-Seq_K562_Human0.92021105
127SPI1_20517297_ChIP-Seq_HL60_Human0.91837212
128CTCF_27219007_Chip-Seq_ERYTHROID_Human0.91619514

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003303_peritoneal_inflammation3.56481034
2MP0004859_abnormal_synaptic_plasticity3.47550231
3MP0005451_abnormal_body_composition3.17620213
4MP0000569_abnormal_digit_pigmentation3.11208083
5MP0001835_abnormal_antigen_presentation2.97992340
6MP0003300_gastrointestinal_ulcer2.72255308
7MP0003183_abnormal_peptide_metabolism2.58159713
8MP0004510_myositis2.55840973
9MP0000685_abnormal_immune_system2.55473589
10MP0008260_abnormal_autophagy2.48410622
11MP0003172_abnormal_lysosome_physiology2.35355441
12MP0001790_abnormal_immune_system2.33235836
13MP0005387_immune_system_phenotype2.33235836
14MP0003436_decreased_susceptibility_to2.24098772
15MP0001800_abnormal_humoral_immune2.13890063
16MP0008961_abnormal_basal_metabolism2.07795655
17MP0002166_altered_tumor_susceptibility1.96515181
18MP0002909_abnormal_adrenal_gland1.96126132
19MP0003191_abnormal_cellular_cholesterol1.92122546
20MP0003705_abnormal_hypodermis_morpholog1.88324847
21MP0003724_increased_susceptibility_to1.79962696
22MP0002452_abnormal_antigen_presenting1.78103605
23MP0005076_abnormal_cell_differentiation1.76384190
24MP0009840_abnormal_foam_cell1.74515884
25MP0000604_amyloidosis1.72105004
26MP0009278_abnormal_bone_marrow1.70713116
27MP0002090_abnormal_vision1.70369015
28MP0005671_abnormal_response_to1.70216022
29MP0002877_abnormal_melanocyte_morpholog1.68115938
30MP0005000_abnormal_immune_tolerance1.65719321
31MP0002398_abnormal_bone_marrow1.64922473
32MP0002723_abnormal_immune_serum1.62761418
33MP0002420_abnormal_adaptive_immunity1.60846719
34MP0001819_abnormal_immune_cell1.60742190
35MP0009785_altered_susceptibility_to1.60729624
36MP0002419_abnormal_innate_immunity1.60099477
37MP0002006_tumorigenesis1.59613409
38MP0009333_abnormal_splenocyte_physiolog1.57751638
39MP0005025_abnormal_response_to1.51004231
40MP0004185_abnormal_adipocyte_glucose1.50244521
41MP0005058_abnormal_lysosome_morphology1.48640265
42MP0003453_abnormal_keratinocyte_physiol1.48410108
43MP0009780_abnormal_chondrocyte_physiolo1.47223005
44MP0004947_skin_inflammation1.45817521
45MP0003635_abnormal_synaptic_transmissio1.43033442
46MP0004808_abnormal_hematopoietic_stem1.42145907
47MP0004130_abnormal_muscle_cell1.40682781
48MP0003763_abnormal_thymus_physiology1.40461444
49MP0000716_abnormal_immune_system1.39818676
50MP0008438_abnormal_cutaneous_collagen1.38997721
51MP0005464_abnormal_platelet_physiology1.38166133
52MP0001849_ear_inflammation1.34824179
53MP0003075_altered_response_to1.31965112
54MP0006082_CNS_inflammation1.30883275
55MP0004858_abnormal_nervous_system1.30597224
56MP0010352_gastrointestinal_tract_polyps1.30258444
57MP0010307_abnormal_tumor_latency1.29879877
58MP0003329_amyloid_beta_deposits1.29533524
59MP0003221_abnormal_cardiomyocyte_apopto1.25619152
60MP0002822_catalepsy1.24749810
61MP0003045_fibrosis1.23765121
62MP0000689_abnormal_spleen_morphology1.22997203
63MP0003091_abnormal_cell_migration1.22227772
64MP0002837_dystrophic_cardiac_calcinosis1.21210320
65MP0002429_abnormal_blood_cell1.16662714
66MP0002722_abnormal_immune_system1.14823518
67MP0005167_abnormal_blood-brain_barrier1.14309647
68MP0002998_abnormal_bone_remodeling1.12294186
69MP0001845_abnormal_inflammatory_respons1.10940887
70MP0005666_abnormal_adipose_tissue1.10608319
71MP0002063_abnormal_learning/memory/cond1.07347259
72MP0000703_abnormal_thymus_morphology1.06956016
73MP0010234_abnormal_vibrissa_follicle1.06589575
74MP0001533_abnormal_skeleton_physiology1.06440085
75MP0001545_abnormal_hematopoietic_system1.06217510
76MP0005397_hematopoietic_system_phenotyp1.06217510
77MP0004084_abnormal_cardiac_muscle1.04758788
78MP0002064_seizures1.04758701
79MP0005166_decreased_susceptibility_to1.04470653
80MP0008569_lethality_at_weaning1.02486080
81MP0002138_abnormal_hepatobiliary_system1.01971634
82MP0004811_abnormal_neuron_physiology1.01680470
83MP0003111_abnormal_nucleus_morphology1.01140746
84MP0003690_abnormal_glial_cell0.99674199
85MP0001915_intracranial_hemorrhage0.99222715
86MP0001730_embryonic_growth_arrest0.98830620
87MP0000371_diluted_coat_color0.98604365
88MP0002009_preneoplasia0.97156439
89MP0003566_abnormal_cell_adhesion0.96572251
90MP0003828_pulmonary_edema0.95521507
91MP0000858_altered_metastatic_potential0.95291736
92MP0005310_abnormal_salivary_gland0.95157211
93MP0003448_altered_tumor_morphology0.94324383
94MP0000013_abnormal_adipose_tissue0.94140201
95MP0005023_abnormal_wound_healing0.94004042
96MP0002148_abnormal_hypersensitivity_rea0.92174286
97MP0000609_abnormal_liver_physiology0.91858905
98MP0001851_eye_inflammation0.91536000
99MP0008874_decreased_physiological_sensi0.90704322
100MP0005375_adipose_tissue_phenotype0.90336736
101MP0010329_abnormal_lipoprotein_level0.89567104
102MP0000350_abnormal_cell_proliferation0.89156613
103MP0008469_abnormal_protein_level0.88255972
104MP0009046_muscle_twitch0.88029345
105MP0002405_respiratory_system_inflammati0.87223638
106MP0003866_abnormal_defecation0.87071484
107MP0005551_abnormal_eye_electrophysiolog0.86773499
108MP0000733_abnormal_muscle_development0.86205791
109MP0003633_abnormal_nervous_system0.85629041
110MP0003656_abnormal_erythrocyte_physiolo0.84354097
111MP0010155_abnormal_intestine_physiology0.84110987
112MP0001853_heart_inflammation0.83174153
113MP0009745_abnormal_behavioral_response0.82963892
114MP0000751_myopathy0.81868095
115MP0008057_abnormal_DNA_replication0.80794086
116MP0001873_stomach_inflammation0.80012959
117MP0000490_abnormal_crypts_of0.79354329
118MP0005257_abnormal_intraocular_pressure0.78843004
119MP0000747_muscle_weakness0.78216898
120MP0005409_darkened_coat_color0.77635088
121MP0004264_abnormal_extraembryonic_tissu0.77110596
122MP0000003_abnormal_adipose_tissue0.77070043
123MP0005584_abnormal_enzyme/coenzyme_acti0.76770733
124MP0003077_abnormal_cell_cycle0.75951824
125MP0001348_abnormal_lacrimal_gland0.75715946
126MP0000313_abnormal_cell_death0.75664077
127MP0009764_decreased_sensitivity_to0.73650467
128MP0001502_abnormal_circadian_rhythm0.70518016
129MP0002078_abnormal_glucose_homeostasis0.69684177
130MP0005621_abnormal_cell_physiology0.68975577
131MP0002396_abnormal_hematopoietic_system0.67030866
132MP0000358_abnormal_cell_content/0.66501310
133MP0001501_abnormal_sleep_pattern0.66393341
134MP0004233_abnormal_muscle_weight0.65793361

Predicted human phenotypes

RankGene SetZ-score
1Central scotoma (HP:0000603)3.60600205
2Elevated erythrocyte sedimentation rate (HP:0003565)3.58335318
3Hyperacusis (HP:0010780)3.00518314
4Fatigue (HP:0012378)2.96142923
5Visual hallucinations (HP:0002367)2.90175561
6Recurrent viral infections (HP:0004429)2.88607501
7Abnormal delayed hypersensitivity skin test (HP:0002963)2.87040821
8Peritonitis (HP:0002586)2.80271646
9Abnormality of the lower motor neuron (HP:0002366)2.79716470
10Hand muscle atrophy (HP:0009130)2.74468140
11Increased cerebral lipofuscin (HP:0011813)2.73032335
12Gastrointestinal stroma tumor (HP:0100723)2.71624937
13Colitis (HP:0002583)2.69996549
14Chronic otitis media (HP:0000389)2.66657127
15Abnormality of macrophages (HP:0004311)2.62561836
16Papilledema (HP:0001085)2.58766297
17Distal upper limb amyotrophy (HP:0007149)2.51173336
18Upper limb amyotrophy (HP:0009129)2.51173336
19Interstitial pulmonary disease (HP:0006530)2.46616455
20Progressive cerebellar ataxia (HP:0002073)2.45319113
21Scotoma (HP:0000575)2.44730155
22Polycythemia (HP:0001901)2.41478198
23Eczematoid dermatitis (HP:0000976)2.40798866
24Recurrent fungal infections (HP:0002841)2.39024297
25Insomnia (HP:0100785)2.35864650
26Recurrent gram-negative bacterial infections (HP:0005420)2.35702007
27Increased connective tissue (HP:0009025)2.34895323
28Hemiplegia (HP:0002301)2.32983339
29Cerebral aneurysm (HP:0004944)2.32092591
30Autoimmune thrombocytopenia (HP:0001973)2.31459574
31Recurrent bronchitis (HP:0002837)2.30526360
32Centrally nucleated skeletal muscle fibers (HP:0003687)2.29932715
33Supranuclear gaze palsy (HP:0000605)2.28331970
34Increased IgE level (HP:0003212)2.26621459
35Cellulitis (HP:0100658)2.25850204
36Protrusio acetabuli (HP:0003179)2.25390666
37Recurrent abscess formation (HP:0002722)2.23808773
38Dysmetric saccades (HP:0000641)2.23448876
39Cholecystitis (HP:0001082)2.22954730
40Abnormal gallbladder physiology (HP:0012438)2.22954730
41Pointed chin (HP:0000307)2.19849564
42Frequent falls (HP:0002359)2.18610141
43Gastrointestinal inflammation (HP:0004386)2.18318883
44Gastrointestinal infarctions (HP:0005244)2.16335261
45Vertebral compression fractures (HP:0002953)2.16181443
46Orchitis (HP:0100796)2.16064856
47Recurrent bacterial skin infections (HP:0005406)2.15349460
48Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.15007815
49Distal lower limb amyotrophy (HP:0008944)2.14916532
50Depression (HP:0000716)2.12887588
51Global brain atrophy (HP:0002283)2.09428180
52Nasal polyposis (HP:0100582)2.08181900
53Agammaglobulinemia (HP:0004432)2.07417737
54Mitral stenosis (HP:0001718)2.07369803
55Striae distensae (HP:0001065)2.07072329
56Myokymia (HP:0002411)2.05964311
57Mediastinal lymphadenopathy (HP:0100721)2.03149737
58Macroorchidism (HP:0000053)2.01893072
59Elfin facies (HP:0004428)2.01747641
60Emphysema (HP:0002097)2.00760923
61Meningitis (HP:0001287)2.00274829
62Inflammation of the large intestine (HP:0002037)1.99969282
63Flat acetabular roof (HP:0003180)1.99692220
64Thin bony cortex (HP:0002753)1.99392427
65Increased neuronal autofluorescent lipopigment (HP:0002074)1.99093802
66Broad face (HP:0000283)1.98721613
67Deep palmar crease (HP:0006191)1.98637137
68Abnormality of the periventricular white matter (HP:0002518)1.97071226
69Slow saccadic eye movements (HP:0000514)1.96929170
70Optic neuritis (HP:0100653)1.95795960
71Retrobulbar optic neuritis (HP:0100654)1.95795960
72T lymphocytopenia (HP:0005403)1.95755329
73Chronic mucocutaneous candidiasis (HP:0002728)1.95118529
74Recurrent cutaneous fungal infections (HP:0011370)1.95118529
75Abnormality of T cell number (HP:0011839)1.93829107
76Long toe (HP:0010511)1.93373514
77Reticulocytosis (HP:0001923)1.93032058
78Periodontitis (HP:0000704)1.93022163
79Abnormality of the fingertips (HP:0001211)1.92486775
80Verrucae (HP:0200043)1.92345524
81Papilloma (HP:0012740)1.92345524
82Vasculitis (HP:0002633)1.92067824
83Postural instability (HP:0002172)1.91122156
84Abnormality of the nasal mucosa (HP:0000433)1.90788372
85Hypergammaglobulinemia (HP:0010702)1.90673690
86Segmental peripheral demyelination/remyelination (HP:0003481)1.89019194
87Pelvic girdle muscle weakness (HP:0003749)1.87627088
88Metaphyseal cupping (HP:0003021)1.87058430
89Resting tremor (HP:0002322)1.86598835
90Deep venous thrombosis (HP:0002625)1.86099310
91Spontaneous hematomas (HP:0007420)1.84725879
92Subacute progressive viral hepatitis (HP:0006572)1.84361681
93Loss of speech (HP:0002371)1.84022161
94Disproportionate tall stature (HP:0001519)1.83551260
95Asymmetry of the thorax (HP:0001555)1.82112029
96Ankyloglossia (HP:0010296)1.82093011
97Abnormality of the peritoneum (HP:0002585)1.81563801
98Hypertensive crisis (HP:0100735)1.80656475
99Generalized hyperpigmentation (HP:0007440)1.80086291
100Cerebral inclusion bodies (HP:0100314)1.79931377
101Chronic obstructive pulmonary disease (HP:0006510)1.79338385
102Obstructive lung disease (HP:0006536)1.79338385
103Impaired smooth pursuit (HP:0007772)1.78914492
104Hemorrhage of the eye (HP:0011885)1.78108575
105Myositis (HP:0100614)1.77456608
106Aortic aneurysm (HP:0004942)1.76882482
107Neuronal loss in central nervous system (HP:0002529)1.76800125
108Premature rupture of membranes (HP:0001788)1.75252172
109Recurrent skin infections (HP:0001581)1.74689381
110Aneurysm (HP:0002617)1.74152899
111Osteomyelitis (HP:0002754)1.74116525
112Myocardial infarction (HP:0001658)1.74046813
113Arterial thrombosis (HP:0004420)1.73428491
114Long palpebral fissure (HP:0000637)1.73358151
115Abnormality of the thoracic spine (HP:0100711)1.73098771
116Abnormality of mucopolysaccharide metabolism (HP:0011020)1.72930470
117Abnormality of polysaccharide metabolism (HP:0011012)1.72930470
118Abnormality of glycosaminoglycan metabolism (HP:0004371)1.72930470
119Chest pain (HP:0100749)1.72856044
120Achilles tendon contracture (HP:0001771)1.72764708
121Hypercortisolism (HP:0001578)1.72384435
122Persistence of primary teeth (HP:0006335)1.72256809
123Abnormality of oral frenula (HP:0000190)1.72201539
124Increased variability in muscle fiber diameter (HP:0003557)1.71922106
125Urinary glycosaminoglycan excretion (HP:0003541)1.71677484
126Mucopolysacchariduria (HP:0008155)1.71677484
127Abnormality of T cells (HP:0002843)1.70986526
128IgA deficiency (HP:0002720)1.70252463
129Renovascular hypertension (HP:0100817)1.69928365
130Obstructive sleep apnea (HP:0002870)1.68250266
131Syringomyelia (HP:0003396)1.67719180
132Spinal cord lesions (HP:0100561)1.67719180
133Dilatation of the ascending aorta (HP:0005111)1.67479893
134Dysostosis multiplex (HP:0000943)1.67148714
135Viral hepatitis (HP:0006562)1.67011233
136Gingivitis (HP:0000230)1.66316891
137Urinary bladder sphincter dysfunction (HP:0002839)1.65531794
138Abnormality of skeletal muscle fiber size (HP:0012084)1.64972842
139Panhypogammaglobulinemia (HP:0003139)1.64229063
140Tetraplegia (HP:0002445)1.63766303
141Polygenic inheritance (HP:0010982)1.63497246
142Abnormality of ocular smooth pursuit (HP:0000617)1.63323863
143Hematochezia (HP:0002573)1.63293284
144Ankle clonus (HP:0011448)1.63059237
145Hepatitis (HP:0012115)1.62829856
146Generalized tonic-clonic seizures (HP:0002069)1.62680689
147Focal seizures (HP:0007359)1.62382865
148Posterior subcapsular cataract (HP:0007787)1.61339415
149Lymphopenia (HP:0001888)1.61119717
150Abnormality of cells of the lymphoid lineage (HP:0012140)1.60720491
151Dislocated radial head (HP:0003083)1.58477707
152Progressive external ophthalmoplegia (HP:0000590)1.57421741
153Abnormality of the Achilles tendon (HP:0005109)1.55259669
154Peripheral hypomyelination (HP:0007182)1.54970821
155Ulnar bowing (HP:0003031)1.54801885
156Restrictive lung disease (HP:0002091)1.54313966
157Decreased motor nerve conduction velocity (HP:0003431)1.54300366
158Neurofibrillary tangles (HP:0002185)1.52857171
159Personality changes (HP:0000751)1.51846436
160Abnormality of liposaccharide metabolism (HP:0010968)1.51543467
161Abnormality of glycosphingolipid metabolism (HP:0004343)1.51543467
162Abnormality of glycolipid metabolism (HP:0010969)1.51543467

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB34.09571788
2PRPF4B4.00794048
3MAP3K133.17023895
4MAP3K93.16893917
5PKN22.76529636
6SMG12.73140803
7ICK2.54315415
8TYK22.53869394
9MAP4K12.37791266
10JAK12.34726433
11IRAK32.11424344
12RIPK12.03504276
13KSR22.01024736
14ERN11.98009204
15MAP2K31.96843241
16MAP3K101.95022481
17FGFR41.94433559
18RIPK41.84377571
19JAK31.76274305
20TBK11.62031354
21TTN1.60313303
22NEK91.58828470
23ALK1.54687617
24EEF2K1.53946660
25CAMKK11.53280646
26SCYL21.51527677
27SIK21.49910390
28PTK61.42896077
29IRAK41.41113112
30TAOK21.28683156
31JAK21.28490259
32SIK11.26947147
33PRKD31.26617652
34NEK11.26223701
35DAPK21.24447586
36PAK61.24444788
37FES1.23468257
38LMTK21.19755187
39PRKCH1.19733423
40NTRK31.13913772
41SGK31.12875302
42MAP3K71.11615740
43MAP3K141.10222232
44LRRK21.07642137
45SYK1.06766899
46STK381.01945069
47ZAP700.99700570
48IKBKE0.98936418
49TAOK30.98912090
50MAPK110.97985605
51ARAF0.97675898
52MAP3K60.96855279
53MARK20.96064632
54CAMK1G0.93136117
55FGFR30.92726802
56RET0.89931306
57KSR10.89578776
58PDGFRA0.88475724
59DAPK10.86859465
60CAMK1D0.86826719
61HCK0.86443825
62CSF1R0.85243793
63PDK10.85152442
64STK100.84904326
65BMX0.84440817
66FLT30.84022585
67NME20.83509970
68MAP3K30.81380533
69NEK20.80341423
70KIT0.79804279
71CSK0.77852546
72CDK60.74916681
73BTK0.74475059
74CDC42BPA0.74379985
75GRK60.74321290
76TAOK10.74136798
77MARK30.72910487
78TLK10.70776666
79SIK30.70363955
80MINK10.70333170
81MAP3K110.67211598
82TESK20.66658678
83MOS0.65594584
84MAP3K10.64680333
85BLK0.64567702
86BRSK10.64337473
87IRAK20.63730789
88DDR20.62689503
89STK110.62452473
90FGR0.61657097
91RAF10.58823736
92HIPK20.58253499
93NTRK10.57974208
94MAP3K80.56199541
95RPS6KA20.56062870
96MAP3K40.55338193
97CLK10.55275551
98RPS6KA40.55129712
99CDK40.54860330
100PRKD20.54465103
101RPS6KB20.53732217
102PDPK10.53083367
103EPHA30.52547356
104PAK40.51601487
105CDK120.49305987
106RPS6KC10.48996082
107RPS6KL10.48996082
108LCK0.48960134
109BRAF0.48642268
110SGK20.48001448
111MTOR0.47750451
112MATK0.46595745
113MAPK120.44813959
114NTRK20.44636561
115LATS20.44582192
116MELK0.44481236
117EPHB10.44400111
118CDK50.44226178
119CAMKK20.43596935
120TYRO30.43315303
121MAP3K20.43228061
122ITK0.42787384
123PHKG10.41841957
124PHKG20.41841957
125MAP3K50.41520555
126MAPK70.41107281
127BRD40.40133614
128TNK20.39487683
129FYN0.38924643
130CDK70.38757647
131BMPR20.38406997
132LYN0.36366601
133PDGFRB0.36057206

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.26448830
2Butirosin and neomycin biosynthesis_Homo sapiens_hsa005242.23700038
3Other glycan degradation_Homo sapiens_hsa005111.99029178
4B cell receptor signaling pathway_Homo sapiens_hsa046621.95441234
5Synaptic vesicle cycle_Homo sapiens_hsa047211.82373244
6Type II diabetes mellitus_Homo sapiens_hsa049301.70261237
7Nitrogen metabolism_Homo sapiens_hsa009101.64000329
8Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.62706269
9Osteoclast differentiation_Homo sapiens_hsa043801.52745556
10Leishmaniasis_Homo sapiens_hsa051401.45370909
11Neurotrophin signaling pathway_Homo sapiens_hsa047221.36354750
12Antigen processing and presentation_Homo sapiens_hsa046121.35102770
13Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.34374448
14Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.33905868
15Toll-like receptor signaling pathway_Homo sapiens_hsa046201.32333659
16Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.28890642
17Primary immunodeficiency_Homo sapiens_hsa053401.27986000
18Chronic myeloid leukemia_Homo sapiens_hsa052201.26762085
19Glioma_Homo sapiens_hsa052141.24959010
20Bladder cancer_Homo sapiens_hsa052191.24516207
21mTOR signaling pathway_Homo sapiens_hsa041501.22285846
22Viral carcinogenesis_Homo sapiens_hsa052031.18253878
23Aldosterone synthesis and secretion_Homo sapiens_hsa049251.16436212
24Type I diabetes mellitus_Homo sapiens_hsa049401.16309198
25Insulin resistance_Homo sapiens_hsa049311.16302863
26Allograft rejection_Homo sapiens_hsa053301.15946482
27Olfactory transduction_Homo sapiens_hsa047401.14022185
28GABAergic synapse_Homo sapiens_hsa047271.13679121
29Insulin secretion_Homo sapiens_hsa049111.13144230
30Chemokine signaling pathway_Homo sapiens_hsa040621.12587935
31Central carbon metabolism in cancer_Homo sapiens_hsa052301.12430928
32Non-small cell lung cancer_Homo sapiens_hsa052231.11941210
33Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.11406442
34Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.10418446
35Notch signaling pathway_Homo sapiens_hsa043301.10187937
36Circadian entrainment_Homo sapiens_hsa047131.09770901
37Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.09255498
38Long-term potentiation_Homo sapiens_hsa047201.08858244
39Thyroid cancer_Homo sapiens_hsa052161.08249181
40Tuberculosis_Homo sapiens_hsa051521.07038721
41Carbohydrate digestion and absorption_Homo sapiens_hsa049731.04259035
42Acute myeloid leukemia_Homo sapiens_hsa052211.04179719
43TNF signaling pathway_Homo sapiens_hsa046681.04132163
44Estrogen signaling pathway_Homo sapiens_hsa049151.03896954
45Measles_Homo sapiens_hsa051621.03876065
46Malaria_Homo sapiens_hsa051441.02787134
47ErbB signaling pathway_Homo sapiens_hsa040121.02411574
48Prolactin signaling pathway_Homo sapiens_hsa049171.02147048
49Hepatitis B_Homo sapiens_hsa051611.01987313
50Thyroid hormone signaling pathway_Homo sapiens_hsa049191.00818990
51Cholinergic synapse_Homo sapiens_hsa047250.99970197
52Autoimmune thyroid disease_Homo sapiens_hsa053200.99876607
53Small cell lung cancer_Homo sapiens_hsa052220.99257273
54NF-kappa B signaling pathway_Homo sapiens_hsa040640.98608814
55Shigellosis_Homo sapiens_hsa051310.98171536
56Adipocytokine signaling pathway_Homo sapiens_hsa049200.97909220
57Prostate cancer_Homo sapiens_hsa052150.96149840
58VEGF signaling pathway_Homo sapiens_hsa043700.95848948
59Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.95156762
60Toxoplasmosis_Homo sapiens_hsa051450.94158790
61HTLV-I infection_Homo sapiens_hsa051660.92808036
62Insulin signaling pathway_Homo sapiens_hsa049100.92480755
63Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.91938892
64Morphine addiction_Homo sapiens_hsa050320.91853083
65Graft-versus-host disease_Homo sapiens_hsa053320.91795692
66Leukocyte transendothelial migration_Homo sapiens_hsa046700.91133997
67T cell receptor signaling pathway_Homo sapiens_hsa046600.90993695
68Influenza A_Homo sapiens_hsa051640.90871568
69Dorso-ventral axis formation_Homo sapiens_hsa043200.90082777
70Apoptosis_Homo sapiens_hsa042100.89497876
71Pancreatic cancer_Homo sapiens_hsa052120.89371329
72Glucagon signaling pathway_Homo sapiens_hsa049220.89013838
73HIF-1 signaling pathway_Homo sapiens_hsa040660.88849908
74Phosphatidylinositol signaling system_Homo sapiens_hsa040700.88575237
75Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.88276140
76RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.87989818
77Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.87727985
78Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.85857120
79Epstein-Barr virus infection_Homo sapiens_hsa051690.85463738
80Lysosome_Homo sapiens_hsa041420.85313667
81Arginine biosynthesis_Homo sapiens_hsa002200.83520768
82Pentose phosphate pathway_Homo sapiens_hsa000300.83083431
83Staphylococcus aureus infection_Homo sapiens_hsa051500.82878366
84Inositol phosphate metabolism_Homo sapiens_hsa005620.82608739
85MicroRNAs in cancer_Homo sapiens_hsa052060.79122529
86Legionellosis_Homo sapiens_hsa051340.78657617
87Amoebiasis_Homo sapiens_hsa051460.78427061
88Oxytocin signaling pathway_Homo sapiens_hsa049210.78066398
89Choline metabolism in cancer_Homo sapiens_hsa052310.76108429
90Proteoglycans in cancer_Homo sapiens_hsa052050.76099155
91Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.75889806
92AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.75473407
93Salmonella infection_Homo sapiens_hsa051320.74842841
94Sphingolipid signaling pathway_Homo sapiens_hsa040710.73764350
95Longevity regulating pathway - mammal_Homo sapiens_hsa042110.73152139
96Endometrial cancer_Homo sapiens_hsa052130.72832709
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.72363752
98African trypanosomiasis_Homo sapiens_hsa051430.72279897
99Dopaminergic synapse_Homo sapiens_hsa047280.71629331
100Pertussis_Homo sapiens_hsa051330.71090800
101Gastric acid secretion_Homo sapiens_hsa049710.70497520
102GnRH signaling pathway_Homo sapiens_hsa049120.69829288
103FoxO signaling pathway_Homo sapiens_hsa040680.69535745
104Herpes simplex infection_Homo sapiens_hsa051680.69317872
105Fructose and mannose metabolism_Homo sapiens_hsa000510.69150119
106Intestinal immune network for IgA production_Homo sapiens_hsa046720.68573281
107Colorectal cancer_Homo sapiens_hsa052100.68324096
108Renin secretion_Homo sapiens_hsa049240.68270955
109Platelet activation_Homo sapiens_hsa046110.68213075
110Viral myocarditis_Homo sapiens_hsa054160.67854249
111Focal adhesion_Homo sapiens_hsa045100.66459718
112Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.65522370
113Prion diseases_Homo sapiens_hsa050200.64623765
114Phospholipase D signaling pathway_Homo sapiens_hsa040720.64478451
115cGMP-PKG signaling pathway_Homo sapiens_hsa040220.62924321
116Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.62889399
117Amphetamine addiction_Homo sapiens_hsa050310.61435540
118Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.60879151
119Renal cell carcinoma_Homo sapiens_hsa052110.60616818
120Salivary secretion_Homo sapiens_hsa049700.59308383
121Endocytosis_Homo sapiens_hsa041440.59191884
122Nicotine addiction_Homo sapiens_hsa050330.58660851
1232-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.58521968
124Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.57783232
125Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.56958825
126MAPK signaling pathway_Homo sapiens_hsa040100.56456384
127Adherens junction_Homo sapiens_hsa045200.56146788
128Jak-STAT signaling pathway_Homo sapiens_hsa046300.55762850
129Lysine degradation_Homo sapiens_hsa003100.55726824
130Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.55562696
131Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.55020549
132Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.54760316
133Dilated cardiomyopathy_Homo sapiens_hsa054140.54670666
134Hepatitis C_Homo sapiens_hsa051600.54615134
135NOD-like receptor signaling pathway_Homo sapiens_hsa046210.53196586
136Hematopoietic cell lineage_Homo sapiens_hsa046400.52731580

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