CNFN

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1keratinocyte differentiation (GO:0030216)9.17001039
2intermediate filament organization (GO:0045109)8.80319849
3hemidesmosome assembly (GO:0031581)8.38527119
4multicellular organismal water homeostasis (GO:0050891)8.32699522
5epidermis development (GO:0008544)7.15995036
6epidermal cell differentiation (GO:0009913)7.15543673
7skin morphogenesis (GO:0043589)7.00558095
8water homeostasis (GO:0030104)6.92350424
9bundle of His cell to Purkinje myocyte communication (GO:0086069)6.45425725
10negative regulation of interleukin-17 production (GO:0032700)5.74670166
11long-chain fatty acid biosynthetic process (GO:0042759)5.60584945
12intermediate filament cytoskeleton organization (GO:0045104)5.52673776
13negative regulation of interferon-gamma production (GO:0032689)5.49101099
14regulation of natural killer cell differentiation (GO:0032823)5.46153090
15intermediate filament-based process (GO:0045103)5.37614942
16adhesion of symbiont to host cell (GO:0044650)5.23415868
17virion attachment to host cell (GO:0019062)5.23415868
18ectoderm development (GO:0007398)5.20833078
19cell wall macromolecule metabolic process (GO:0044036)4.95059730
20cell wall macromolecule catabolic process (GO:0016998)4.95059730
21gap junction assembly (GO:0016264)4.60767105
22keratinocyte proliferation (GO:0043616)4.44457967
23hair follicle morphogenesis (GO:0031069)4.39717738
24fatty acid elongation (GO:0030497)4.36630832
25apical protein localization (GO:0045176)4.35508645
26adhesion of symbiont to host (GO:0044406)4.34182861
27hair cell differentiation (GO:0035315)4.24086031
28antimicrobial humoral response (GO:0019730)4.03673451
29keratinocyte development (GO:0003334)4.00210743
30linoleic acid metabolic process (GO:0043651)3.99612259
31sequestering of metal ion (GO:0051238)3.99020799
32regulation of keratinocyte differentiation (GO:0045616)3.71133757
33detection of external biotic stimulus (GO:0098581)3.65210120
34negative regulation of bone mineralization (GO:0030502)3.64275377
35phosphatidylinositol acyl-chain remodeling (GO:0036149)3.58653175
36regulation of ruffle assembly (GO:1900027)3.49960616
37lipoxygenase pathway (GO:0019372)3.42939068
38epithelium development (GO:0060429)3.37233864
39citrulline biosynthetic process (GO:0019240)3.37123663
40hair cycle process (GO:0022405)3.36861565
41molting cycle process (GO:0022404)3.36861565
42negative regulation of keratinocyte proliferation (GO:0010839)3.35243926
43atrioventricular valve morphogenesis (GO:0003181)3.33614239
44defense response to fungus (GO:0050832)3.29048703
45skin development (GO:0043588)3.28353178
46regulation of interleukin-17 production (GO:0032660)3.24462827
47phosphatidylserine acyl-chain remodeling (GO:0036150)3.19001559
48negative regulation of biomineral tissue development (GO:0070168)3.18897667
49detection of biotic stimulus (GO:0009595)3.16700050
50regulation of T cell chemotaxis (GO:0010819)3.16437722
51positive regulation of T cell chemotaxis (GO:0010820)3.16437722
52regulation of natural killer cell activation (GO:0032814)3.13954314
53transepithelial transport (GO:0070633)3.08758932
54planar cell polarity pathway involved in neural tube closure (GO:0090179)3.06264641
55ceramide biosynthetic process (GO:0046513)3.05979492
56asymmetric protein localization (GO:0008105)3.03222465
57intestinal epithelial cell development (GO:0060576)3.01576128
58* keratinization (GO:0031424)20.5293563
59localization within membrane (GO:0051668)2.97452049
60cell-substrate junction assembly (GO:0007044)2.91429628
61detection of bacterium (GO:0016045)2.90351868
62glucosamine-containing compound catabolic process (GO:1901072)2.88580735
63phosphatidylserine metabolic process (GO:0006658)2.86890177
64negative regulation of homotypic cell-cell adhesion (GO:0034111)2.86487976
65vitamin A metabolic process (GO:0006776)2.86038329
66regulation of transforming growth factor beta1 production (GO:0032908)2.85755734
67regulation of epidermis development (GO:0045682)2.83891157
68regulation of epidermal cell differentiation (GO:0045604)2.83549493
69negative regulation of cytokine-mediated signaling pathway (GO:0001960)2.80729270
70ventricular cardiac muscle cell action potential (GO:0086005)2.80720728
71positive regulation of p38MAPK cascade (GO:1900745)2.79997559
72positive regulation of monocyte chemotaxis (GO:0090026)2.79848958
73negative regulation of cell fate specification (GO:0009996)2.79829054
74positive regulation of epidermis development (GO:0045684)2.79695960
75surfactant homeostasis (GO:0043129)2.78260378
76regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)2.77747883
77sphingoid metabolic process (GO:0046519)2.77145891
78phosphatidylglycerol acyl-chain remodeling (GO:0036148)2.76108786
79regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.74461960
80establishment of tissue polarity (GO:0007164)2.74250199
81establishment of planar polarity (GO:0001736)2.74250199
82defense response to Gram-negative bacterium (GO:0050829)2.74054177
83long-chain fatty-acyl-CoA metabolic process (GO:0035336)2.73348498
84membrane raft organization (GO:0031579)2.71824829
85negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)2.70489707
86phosphatidylethanolamine acyl-chain remodeling (GO:0036152)2.67117680
87sphingosine metabolic process (GO:0006670)2.66572213
88actin-myosin filament sliding (GO:0033275)2.65961184
89muscle filament sliding (GO:0030049)2.65961184
90eyelid development in camera-type eye (GO:0061029)2.65078593
91tooth mineralization (GO:0034505)2.64998953
92negative regulation of response to cytokine stimulus (GO:0060761)2.64213277
93regulation of axon regeneration (GO:0048679)2.63479843
94regulation of neuron projection regeneration (GO:0070570)2.63479843
95hair follicle development (GO:0001942)2.62949860
96chemical homeostasis within a tissue (GO:0048875)2.62602189
97regulation of T cell migration (GO:2000404)2.62112634
98superoxide anion generation (GO:0042554)2.58119892
99lymph vessel development (GO:0001945)2.57008765
100positive regulation of hair cycle (GO:0042635)2.50379857
101positive regulation of hair follicle development (GO:0051798)2.50379857
102regulation of skeletal muscle contraction (GO:0014819)2.50349040
103positive regulation of granulocyte chemotaxis (GO:0071624)2.48531277
104detection of other organism (GO:0098543)2.46295375
105lateral sprouting from an epithelium (GO:0060601)2.44619511
106positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745)2.44527346
107regulation of cell proliferation involved in kidney development (GO:1901722)2.43970325
108positive regulation of glomerulus development (GO:0090193)2.43583508
109positive regulation of endothelial cell differentiation (GO:0045603)2.43058283
110phospholipid catabolic process (GO:0009395)2.39816267
111regulation of skeletal muscle cell differentiation (GO:2001014)2.38765777
112positive regulation of epidermal cell differentiation (GO:0045606)2.38559721
113alditol phosphate metabolic process (GO:0052646)2.37943860
114regulation of hair cycle (GO:0042634)2.37350334
115diol metabolic process (GO:0034311)2.35683065
116epithelial cell-cell adhesion (GO:0090136)2.34757236
117regulation of hair follicle development (GO:0051797)2.34679318
118phospholipid efflux (GO:0033700)2.34443087
119polarized epithelial cell differentiation (GO:0030859)2.34436775
120phosphatidylcholine acyl-chain remodeling (GO:0036151)2.33313105
121regulation of cholesterol homeostasis (GO:2000188)2.31877891
122fatty-acyl-CoA metabolic process (GO:0035337)2.31207904
123regulation of cardioblast differentiation (GO:0051890)2.31019492
124response to phenylpropanoid (GO:0080184)2.29605849
125fibrinolysis (GO:0042730)2.28291748
126O-glycan processing (GO:0016266)2.27759819
127regulation of monocyte chemotaxis (GO:0090025)2.26887314
128wound healing (GO:0042060)2.26653222
129negative regulation of cell fate commitment (GO:0010454)2.26348640
130actin-mediated cell contraction (GO:0070252)2.25550586
131response to UV-B (GO:0010224)2.24693791
132regulation of heart rate by cardiac conduction (GO:0086091)2.24433276
133positive regulation of extrinsic apoptotic signaling pathway via death domain receptors (GO:1902043)2.23840142
134regulation of protein localization to cell surface (GO:2000008)2.23240748
135epithelial cell differentiation (GO:0030855)2.22285744
136plasma membrane repair (GO:0001778)2.21780335
137response to fungus (GO:0009620)2.21256504
138non-canonical Wnt signaling pathway (GO:0035567)2.19920537
139positive regulation of cholesterol efflux (GO:0010875)2.19700220
140negative regulation of cell-cell adhesion (GO:0022408)2.19496174
141negative regulation of stress fiber assembly (GO:0051497)2.18468405
142long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)2.17538368
143molting cycle (GO:0042303)19.4192343
144hair cycle (GO:0042633)19.4192343
145establishment of skin barrier (GO:0061436)14.2351960
146desmosome organization (GO:0002934)13.1393987
147regulation of water loss via skin (GO:0033561)12.4411980
148peptide cross-linking (GO:0018149)10.5865279

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse4.17912982
2P63_26484246_Chip-Seq_KERATINOCYTES_Human3.51863119
3ZNF652_21678463_ChIP-ChIP_ZR75-1_Human2.85573575
4ESR1_21235772_ChIP-Seq_MCF-7_Human2.54386972
5ESR1_20079471_ChIP-ChIP_T-47D_Human2.49385029
6CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.48508508
7SMAD4_19686287_ChIP-ChIP_HaCaT_Human2.39681678
8SOX9_24532713_ChIP-Seq_HFSC_Mouse2.30775415
9CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human2.21874013
10TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.08241313
11TP63_17297297_ChIP-ChIP_HaCaT_Human14.8306160
12SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.97009058
13SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.97009058
14ESR2_21235772_ChIP-Seq_MCF-7_Human1.96434154
15PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.94939893
16TRIM28_21343339_ChIP-Seq_HEK293_Human1.89257105
17VDR_22108803_ChIP-Seq_LS180_Human1.73009477
18FOXO3_23340844_ChIP-Seq_DLD1_Human1.64851366
19RARG_19884340_ChIP-ChIP_MEFs_Mouse1.61618401
20CTCF_20526341_ChIP-Seq_ESCs_Human1.58311702
21FOXM1_26456572_ChIP-Seq_MCF-7_Human1.57487165
22ZNF263_19887448_ChIP-Seq_K562_Human1.55108841
23GATA6_21074721_ChIP-Seq_CACO-2_Mouse1.55054504
24PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.53597238
25EGR1_19032775_ChIP-ChIP_M12_Human1.51853436
26HTT_18923047_ChIP-ChIP_STHdh_Human1.49975274
27ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.46628710
28RACK7_27058665_Chip-Seq_MCF-7_Human1.45182564
29TP63_22573176_ChIP-Seq_HFKS_Human1.42600852
30* CTCF_27219007_Chip-Seq_Bcells_Human1.40917236
31BMI1_19503595_ChIP-Seq_MEFsC_Mouse1.37264494
32TP63_23658742_ChIP-Seq_EP156T_Human1.37209261
33GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human1.37205339
34GATA6_21074721_ChIP-Seq_CACO-2_Human1.35995524
35ERG_20517297_ChIP-Seq_VCAP_Human1.35219371
36SOX2_27498859_Chip-Seq_STOMACH_Mouse1.34988959
37FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.34286854
38* ATF3_27146783_Chip-Seq_COLON_Human1.32572899
39SOX2_20726797_ChIP-Seq_SW620_Human1.32079814
40P63_20808887_ChIP-Seq_KERATINOCYTES_Human1.26656921
41GATA3_24758297_ChIP-Seq_MCF-7_Human1.26114761
42TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.25831781
43DNAJC2_21179169_ChIP-ChIP_NT2_Human1.24645403
44YY1_22570637_ChIP-Seq_MALME-3M_Human1.23010445
45KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.22875124
46KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.22643903
47HIF1A_21447827_ChIP-Seq_MCF-7_Human1.21414857
48ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.21075460
49UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.20439257
50NANOG_20526341_ChIP-Seq_ESCs_Human1.20019429
51PPAR_26484153_Chip-Seq_NCI-H1993_Human1.19304054
52LXR_22292898_ChIP-Seq_THP-1_Human1.19020631
53* E2F1_20622854_ChIP-Seq_HELA_Human1.16289347
54SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.16274507
55KLF5_25053715_ChIP-Seq_YYC3_Human1.16004816
56CJUN_26792858_Chip-Seq_BT549_Human1.15121299
57TP53_20018659_ChIP-ChIP_R1E_Mouse1.14601065
58RUNX1_27514584_Chip-Seq_MCF-7_Human1.13319930
59CSB_26484114_Chip-Seq_FIBROBLAST_Human1.13317233
60CEBPB_22108803_ChIP-Seq_LS180_Human1.12984273
61BCOR_27268052_Chip-Seq_Bcells_Human1.12735717
62TAF2_19829295_ChIP-Seq_ESCs_Human1.09934127
63AR_21572438_ChIP-Seq_LNCaP_Human1.09813477
64RXR_22108803_ChIP-Seq_LS180_Human1.09693618
65TCF4_18268006_ChIP-ChIP_LS174T_Human1.09651675
66HNFA_21074721_ChIP-Seq_CACO-2_Human1.08797454
67SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.07680959
68GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.07334447
69UBF1/2_26484160_Chip-Seq_HMECs_Human1.06565378
70TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human1.05846731
71CEBPA_26348894_ChIP-Seq_LIVER_Mouse1.02745593
72VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.01729999
73ZNF217_24962896_ChIP-Seq_MCF-7_Human1.01288635
74TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.01190463
75TP53_18474530_ChIP-ChIP_U2OS_Human1.01107969
76JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.00454530
77DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.00229323
78* SUZ12_27294783_Chip-Seq_ESCs_Mouse0.99315104
79* SA1_27219007_Chip-Seq_ERYTHROID_Human0.99091530
80BCL6_27268052_Chip-Seq_Bcells_Human0.98197663
81FOXH1_21741376_ChIP-Seq_EPCs_Human0.97532524
82CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse0.96971539
83TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human0.95717954
84FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.95675353
85JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94979743
86STAT6_21828071_ChIP-Seq_BEAS2B_Human0.94724628
87P53_21459846_ChIP-Seq_SAOS-2_Human0.94298624
88FOXA1_25552417_ChIP-Seq_VCAP_Human0.93365195
89AR_20517297_ChIP-Seq_VCAP_Human0.92205068
90CDX2_20551321_ChIP-Seq_CACO-2_Human0.90994253
91GATA4_25053715_ChIP-Seq_YYC3_Human0.90388137
92CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.90254537
93AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.88039617
94* P68_20966046_ChIP-Seq_HELA_Human0.86543703
95MNX1_26342078_ChIP-Seq_MIN6-4N_Mouse0.85774271
96SMC4_20622854_ChIP-Seq_HELA_Human0.85715809
97ELF5_23300383_ChIP-Seq_T47D_Human0.85572197
98CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.85480009
99NCOR_22424771_ChIP-Seq_293T_Human0.84847601
100BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.84161674
101TP63_19390658_ChIP-ChIP_HaCaT_Human0.84110787
102SMAD3_21741376_ChIP-Seq_HESCs_Human0.83952878
103AHR_22903824_ChIP-Seq_MCF-7_Human0.83447650
104FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.83172513
105JARID2_20075857_ChIP-Seq_MESCs_Mouse0.80461154
106STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse0.80458048
107EZH2_27294783_Chip-Seq_ESCs_Mouse0.79998325
108AR_25329375_ChIP-Seq_VCAP_Human0.79949026
109PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.79850478
110NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.79067593
111RAC3_21632823_ChIP-Seq_H3396_Human0.78589929
112P300_27058665_Chip-Seq_ZR-75-30cells_Human0.78009362
113RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.77239982
114RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.77088804
115RBPJ_21746931_ChIP-Seq_IB4_Human0.76339986
116FOXH1_21741376_ChIP-Seq_ESCs_Human0.75989155
117RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.75850606
118EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.75509290
119GATA6_25053715_ChIP-Seq_YYC3_Human0.75214481
120FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.75166056
121ERG_21242973_ChIP-ChIP_JURKAT_Human0.75134120
122SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.74601056
123ERA_21632823_ChIP-Seq_H3396_Human0.72968805
124JARID1B-DAIN_22020125_ChIP-Seq_ESCs_Mouse0.72214859
125CDX2_19796622_ChIP-Seq_MESCs_Mouse0.71991935
126ELF1_20517297_ChIP-Seq_JURKAT_Human0.71348129
127ARNT_22903824_ChIP-Seq_MCF-7_Human0.69504582
128CLOCK_20551151_ChIP-Seq_293T_Human0.68935501
129SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.67954663
130STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse0.66694713
131SA1_27219007_Chip-Seq_Bcells_Human0.66682009
132EZH2_27304074_Chip-Seq_ESCs_Mouse0.64171789
133RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.63883803
134SPI1_20517297_ChIP-Seq_HL60_Human0.63504141
135TBX20_22328084_ChIP-Seq_HEART_Mouse0.63412461

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002796_impaired_skin_barrier8.27148508
2MP0005275_abnormal_skin_tensile6.65876545
3MP0000579_abnormal_nail_morphology6.16964634
4MP0010234_abnormal_vibrissa_follicle5.77279039
5MP0005501_abnormal_skin_physiology5.13119129
6MP0002098_abnormal_vibrissa_morphology3.74644560
7MP0000647_abnormal_sebaceous_gland3.69003774
8MP0010678_abnormal_skin_adnexa3.34108005
9MP0000383_abnormal_hair_follicle3.28640890
10MP0001216_abnormal_epidermal_layer3.24085808
11MP0003941_abnormal_skin_development3.23664148
12MP0004381_abnormal_hair_follicle3.10480081
13MP0010771_integument_phenotype2.95859901
14MP0002060_abnormal_skin_morphology2.95473273
15MP0003705_abnormal_hypodermis_morpholog2.83348599
16MP0000377_abnormal_hair_follicle2.81379788
17MP0004947_skin_inflammation2.80221907
18MP0000467_abnormal_esophagus_morphology2.77548900
19MP0003878_abnormal_ear_physiology2.62007080
20MP0005377_hearing/vestibular/ear_phenot2.62007080
21MP0003453_abnormal_keratinocyte_physiol2.56727093
22MP0002254_reproductive_system_inflammat2.53185847
23MP0005451_abnormal_body_composition2.49975664
24MP0000427_abnormal_hair_cycle2.43207615
25MP0004043_abnormal_pH_regulation2.33935769
26MP0000762_abnormal_tongue_morphology2.20458892
27MP0002234_abnormal_pharynx_morphology1.80126280
28MP0001243_abnormal_dermal_layer1.75881923
29MP0009931_abnormal_skin_appearance1.71243367
30MP0003191_abnormal_cellular_cholesterol1.66068155
31MP0000367_abnormal_coat/_hair1.65218016
32MP0004185_abnormal_adipocyte_glucose1.50987859
33MP0003566_abnormal_cell_adhesion1.48202307
34MP0001191_abnormal_skin_condition1.47790639
35MP0005409_darkened_coat_color1.07434401
36MP0001851_eye_inflammation0.98966876
37MP0002138_abnormal_hepatobiliary_system0.96704364
38MP0001346_abnormal_lacrimal_gland0.86739923
39MP0000465_gastrointestinal_hemorrhage0.86046748
40MP0009053_abnormal_anal_canal0.84855822
41MP0002095_abnormal_skin_pigmentation0.74683306
42MP0001340_abnormal_eyelid_morphology0.73212014
43MP0005023_abnormal_wound_healing0.72833825
44MP0003950_abnormal_plasma_membrane0.72507742
45MP0000566_synostosis0.69494024
46MP0004782_abnormal_surfactant_physiolog0.66930579
47MP0001784_abnormal_fluid_regulation0.65886494
48MP0005503_abnormal_tendon_morphology0.65881759
49MP0009333_abnormal_splenocyte_physiolog0.64481502
50MP0003755_abnormal_palate_morphology0.63772104
51MP0008004_abnormal_stomach_pH0.63226003
52MP0001849_ear_inflammation0.62618940
53MP0000751_myopathy0.61207170
54MP0001485_abnormal_pinna_reflex0.60995317
55MP0008438_abnormal_cutaneous_collagen0.60505018
56MP0009780_abnormal_chondrocyte_physiolo0.59367325
57MP0000749_muscle_degeneration0.57884177
58MP0002282_abnormal_trachea_morphology0.57548547
59MP0003315_abnormal_perineum_morphology0.55156321
60MP0001188_hyperpigmentation0.53537318
61MP0010030_abnormal_orbit_morphology0.52942891
62MP0003011_delayed_dark_adaptation0.50390856
63MP0002877_abnormal_melanocyte_morpholog0.49646665
64MP0005666_abnormal_adipose_tissue0.49020263
65MP0002177_abnormal_outer_ear0.44818413
66MP0010352_gastrointestinal_tract_polyps0.44661259
67MP0002249_abnormal_larynx_morphology0.43224169
68MP0004264_abnormal_extraembryonic_tissu0.42686752
69MP0000747_muscle_weakness0.41076852
70MP0000627_abnormal_mammary_gland0.40939694
71MP0002009_preneoplasia0.38580704
72MP0002111_abnormal_tail_morphology0.37702485
73MP0000750_abnormal_muscle_regeneration0.36038896
74MP0005375_adipose_tissue_phenotype0.35426796
75MP0004197_abnormal_fetal_growth/weight/0.34509966
76MP0006054_spinal_hemorrhage0.32592407
77MP0003638_abnormal_response/metabolism_0.31266771
78MP0000003_abnormal_adipose_tissue0.31156246
79MP0004272_abnormal_basement_membrane0.30758248
80MP0005670_abnormal_white_adipose0.29648842
81MP0001765_abnormal_ion_homeostasis0.29254149
82MP0000759_abnormal_skeletal_muscle0.27812208
83MP0000733_abnormal_muscle_development0.27343122
84MP0000678_abnormal_parathyroid_gland0.26956340
85MP0010368_abnormal_lymphatic_system0.26644663
86MP0003385_abnormal_body_wall0.25953971
87MP0009672_abnormal_birth_weight0.25940540
88MP0005076_abnormal_cell_differentiation0.24870904
89MP0008961_abnormal_basal_metabolism0.24841748
90MP0005508_abnormal_skeleton_morphology0.23701525
91MP0004087_abnormal_muscle_fiber0.23447073
92MP0009379_abnormal_foot_pigmentation0.22896128
93MP0001502_abnormal_circadian_rhythm0.22071283
94MP0005620_abnormal_muscle_contractility0.21912857
95MP0002166_altered_tumor_susceptibility0.21837801
96MP0009115_abnormal_fat_cell0.21448454
97MP0000371_diluted_coat_color0.20752893
98MP0001756_abnormal_urination0.20650871
99MP0001186_pigmentation_phenotype0.19960550
100MP0000470_abnormal_stomach_morphology0.19721190
101MP0002697_abnormal_eye_size0.19370769
102MP0003763_abnormal_thymus_physiology0.19349666
103MP0005330_cardiomyopathy0.18886596
104MP0002896_abnormal_bone_mineralization0.18571501
105MP0004019_abnormal_vitamin_homeostasis0.18059827
106MP0001299_abnormal_eye_distance/0.17712290
107MP0000432_abnormal_head_morphology0.17703930
108MP0002106_abnormal_muscle_physiology0.17558508
109MP0004885_abnormal_endolymph0.16657884
110MP0003329_amyloid_beta_deposits0.16232734
111MP0005193_abnormal_anterior_eye0.16149339
112MP0003937_abnormal_limbs/digits/tail_de0.15685258
113MP0005636_abnormal_mineral_homeostasis0.15410583
114MP0000013_abnormal_adipose_tissue0.15328694
115MP0005499_abnormal_olfactory_system0.14933712
116MP0005394_taste/olfaction_phenotype0.14933712
117MP0009250_abnormal_appendicular_skeleto0.14642804
118MP0002233_abnormal_nose_morphology0.14562003
119MP0002006_tumorigenesis0.14188710
120MP0000538_abnormal_urinary_bladder0.14163851
121MP0000049_abnormal_middle_ear0.14098302
122MP0002837_dystrophic_cardiac_calcinosis0.14022241
123MP0001177_atelectasis0.13284270
124MP0001879_abnormal_lymphatic_vessel0.13278838
125MP0001286_abnormal_eye_development0.13134429
126MP0003436_decreased_susceptibility_to0.12788983
127MP0002972_abnormal_cardiac_muscle0.12552381
128MP0008789_abnormal_olfactory_epithelium0.12258943
129MP0009384_cardiac_valve_regurgitation0.12242803
130MP0003567_abnormal_fetal_cardiomyocyte0.12004613
131MP0005365_abnormal_bile_salt0.11403163
132MP0002075_abnormal_coat/hair_pigmentati0.11400441
133MP0005388_respiratory_system_phenotype0.09747649
134MP0002133_abnormal_respiratory_system0.09747649
135MP0001853_heart_inflammation0.09525309
136MP0002081_perinatal_lethality0.09135664
137MP0003828_pulmonary_edema0.08737818
138MP0003806_abnormal_nucleotide_metabolis0.07974899

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of nail color (HP:0100643)9.92271313
2Hypotrichosis (HP:0001006)9.27920216
3Increased IgE level (HP:0003212)8.93206841
4Woolly hair (HP:0002224)7.26569660
5Palmoplantar hyperkeratosis (HP:0000972)6.47312167
6Onycholysis (HP:0001806)6.42872645
7Plantar hyperkeratosis (HP:0007556)6.36126193
8Thick nail (HP:0001805)6.28758825
9Congenital ichthyosiform erythroderma (HP:0007431)6.11076010
10Palmar hyperkeratosis (HP:0010765)6.10507693
11Oral leukoplakia (HP:0002745)6.07622855
12Pustule (HP:0200039)5.79842195
13Pili torti (HP:0003777)5.58559941
14Congenital nonbullous ichthyosiform erythroderma (HP:0007479)5.53125358
15Fragile nails (HP:0001808)5.50433460
16Right ventricular cardiomyopathy (HP:0011663)5.30699141
17Erythroderma (HP:0001019)5.21382591
18Abnormality of secondary sexual hair (HP:0009888)5.01094279
19Abnormality of the axillary hair (HP:0100134)5.01094279
20Nail dystrophy (HP:0008404)4.91668814
21Erythema (HP:0010783)4.78979324
22Alopecia of scalp (HP:0002293)4.66457685
23Brittle hair (HP:0002299)4.51964745
24Milia (HP:0001056)4.25230847
25Follicular hyperkeratosis (HP:0007502)4.17734564
26Conjunctival hamartoma (HP:0100780)4.01967625
27Abnormal blistering of the skin (HP:0008066)3.95937501
28Gangrene (HP:0100758)3.83806657
29Absent eyelashes (HP:0000561)3.73309510
30Ectropion (HP:0000656)3.68920989
31Abnormality of hair growth rate (HP:0011363)3.66006414
32Slow-growing hair (HP:0002217)3.66006414
33Absent hair (HP:0002298)3.63604405
34Furrowed tongue (HP:0000221)3.54290066
35Corneal erosion (HP:0200020)3.52189854
36Abnormal hair laboratory examination (HP:0003328)3.47252452
37Palmoplantar keratoderma (HP:0000982)3.40290064
38Parakeratosis (HP:0001036)3.36544680
39Hyporeflexia of lower limbs (HP:0002600)3.31466478
40Hypohidrosis (HP:0000966)3.21386207
41Amniotic constriction ring (HP:0009775)3.08762183
42Abnormality of placental membranes (HP:0011409)3.08762183
43Villous atrophy (HP:0011473)3.05123942
44Abnormality of small intestinal villus morphology (HP:0011472)3.05123942
45Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.94354643
46Sparse eyelashes (HP:0000653)2.93703802
47Ridged nail (HP:0001807)2.93664300
48Lip pit (HP:0100267)2.91387440
49Muscle fiber inclusion bodies (HP:0100299)2.90139584
50Autoamputation (HP:0001218)2.89832557
51Pruritus (HP:0000989)2.89513660
52Distal arthrogryposis (HP:0005684)2.83596295
53Round ear (HP:0100830)2.78330090
54Natal tooth (HP:0000695)2.77661920
55Nemaline bodies (HP:0003798)2.74668136
56Distal lower limb muscle weakness (HP:0009053)2.73504148
57Type 1 muscle fiber predominance (HP:0003803)2.73248478
58Curly hair (HP:0002212)2.72219576
59Advanced eruption of teeth (HP:0006288)2.66775298
60Hypergammaglobulinemia (HP:0010702)2.63767111
61Urticaria (HP:0001025)2.56056719
62Ventricular tachycardia (HP:0004756)2.55100175
63Increased connective tissue (HP:0009025)2.55091510
64Hamartoma of the eye (HP:0010568)2.51096441
65Hyperactive renin-angiotensin system (HP:0000841)2.49501277
66Myopathic facies (HP:0002058)2.38148531
67Fatigable weakness (HP:0003473)2.37471996
68Abnormality of the neuromuscular junction (HP:0003398)2.37471996
69Laryngomalacia (HP:0001601)2.33469100
70Lack of skin elasticity (HP:0100679)2.30874685
71Ulnar deviation of the wrist (HP:0003049)2.29412105
72Acanthosis nigricans (HP:0000956)2.27405839
73Exercise-induced myalgia (HP:0003738)2.27382266
74Neck muscle weakness (HP:0000467)2.19162792
75Corneal dystrophy (HP:0001131)2.17534962
76Atrophic scars (HP:0001075)2.15315852
77Calcaneovalgus deformity (HP:0001848)2.10612209
78Hypoplastic labia majora (HP:0000059)2.10580942
79Muscle fiber splitting (HP:0003555)2.07401829
80Hyperhidrosis (HP:0000975)2.03535972
81Fine hair (HP:0002213)2.03281239
82Anonychia (HP:0001798)2.02675120
83Areflexia of lower limbs (HP:0002522)2.01378031
84Sparse scalp hair (HP:0002209)1.98141996
85Concave nail (HP:0001598)1.97908897
86Multifactorial inheritance (HP:0001426)1.95287552
87Absent phalangeal crease (HP:0006109)1.94889547
88Hyperkalemia (HP:0002153)1.92875654
89Abnormality of the labia majora (HP:0012881)1.92098532
90Deformed tarsal bones (HP:0008119)1.87433085
91Recurrent corneal erosions (HP:0000495)1.82373505
92Distal lower limb amyotrophy (HP:0008944)1.78827411
93Achilles tendon contracture (HP:0001771)1.75607282
94Dehydration (HP:0001944)1.74950090
95Difficulty running (HP:0009046)1.74932485
96Oligodontia (HP:0000677)1.72309856
97Blepharitis (HP:0000498)1.71381170
98Sepsis (HP:0100806)1.71249314
99Chronic bronchitis (HP:0004469)1.70603731
100Aplasia cutis congenita (HP:0001057)1.70043105
101Congenital, generalized hypertrichosis (HP:0004540)1.69607874
102Amelogenesis imperfecta (HP:0000705)1.69153865
103Sudden death (HP:0001699)1.68131067
104Malignant hyperthermia (HP:0002047)1.67959612
105Preauricular skin tag (HP:0000384)1.67505894
106Ventricular fibrillation (HP:0001663)1.66103926
107Paralysis (HP:0003470)1.65109172
108Unilateral renal agenesis (HP:0000122)1.64907955
109Exercise-induced muscle cramps (HP:0003710)1.63774401
110Carious teeth (HP:0000670)1.63742977
111Eczematoid dermatitis (HP:0000976)1.63144955
112Split foot (HP:0001839)1.62550584
113Seborrheic dermatitis (HP:0001051)1.60758123
114Abnormality of the Achilles tendon (HP:0005109)1.59987713
115Papilloma (HP:0012740)1.59237171
116Verrucae (HP:0200043)1.59237171
117Abnormality of the fingernails (HP:0001231)1.58556036
118Abnormal finger flexion creases (HP:0006143)1.56801213
119Abnormality of skeletal muscle fiber size (HP:0012084)1.56763549
120Labial hypoplasia (HP:0000066)1.56461348
121Melanocytic nevus (HP:0000995)1.56163192
122Skin ulcer (HP:0200042)1.54967619
123Nasal polyposis (HP:0100582)1.50952763
124Dry skin (HP:0000958)1.49602056
125Dry hair (HP:0011359)1.48540930
126Increased variability in muscle fiber diameter (HP:0003557)1.48363000
127Hypoplastic female external genitalia (HP:0012815)1.47275793
128Hypoplastic toenails (HP:0001800)1.47082989
129Skin tags (HP:0010609)1.46218800
130Abnormality of the salivary glands (HP:0010286)1.45919573
131Recurrent bacterial skin infections (HP:0005406)1.45066434
132Decreased circulating renin level (HP:0003351)1.44676289
133Keratoconjunctivitis sicca (HP:0001097)1.44475687
134Skin pits (HP:0100276)1.43597173
135Asthma (HP:0002099)1.37142658
136Cystic hygroma (HP:0000476)1.34425014
137Hypokalemic alkalosis (HP:0001949)1.31904340
138Abnormality of chloride homeostasis (HP:0011422)1.31442571
139Keratoconjunctivitis (HP:0001096)1.28236204

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAPKAPK34.88020836
2TTN4.08573110
3FER3.78560124
4MAP3K33.73979343
5PIK3CG3.64006481
6TGFBR13.56084109
7ERN13.33575997
8MST1R2.89241895
9EPHA22.74577825
10CAMK1D2.72280067
11WNK12.60603972
12TAOK12.42693132
13CAMK1G2.28796908
14SGK4942.27556205
15SGK2232.27556205
16MAP3K112.18375317
17EPHB22.15683144
18RPS6KB22.15593107
19OBSCN2.15305976
20MAP3K22.15133909
21TRIB32.10854901
22MAP3K61.99791399
23MST41.98152970
24MAP2K31.91303985
25TAF11.77313120
26VRK21.77083213
27LATS11.76082637
28MAP2K61.74647130
29NME11.73637626
30STK391.70012814
31MAP3K121.69551815
32SGK21.69451615
33FGFR11.63427591
34BCR1.61035646
35WNK41.52527441
36IRAK11.49892559
37SGK31.49584120
38EPHB11.48170263
39EEF2K1.43569377
40RIPK11.42194573
41GRK61.31571584
42PIM21.30628613
43FGFR41.30091905
44MAP3K11.27201217
45MAP3K71.25210849
46MARK21.24912734
47BLK1.20500419
48TRPM71.20122990
49LRRK21.14814014
50EPHA31.12871713
51DMPK1.11630295
52PHKG21.08745434
53PHKG11.08745434
54LATS21.05625830
55PTK61.05620721
56TGFBR20.98279260
57STK240.97819413
58RPS6KA40.96007900
59MAPKAPK20.94428686
60DYRK1B0.90847046
61MET0.89633441
62CDK60.86460328
63FGFR30.84883538
64MAPKAPK50.84258180
65NLK0.83574050
66MAP2K40.83198319
67ERBB30.83001501
68MAP2K10.82904864
69TESK10.82198772
70IRAK20.79919837
71DDR20.79306067
72FGFR20.74215472
73MAP3K90.74035230
74IKBKB0.69726439
75STK160.69155735
76PRKD10.67851146
77ABL20.67113643
78TYK20.65178232
79MAPK120.64558448
80NEK10.63069813
81AKT30.62653329
82RPS6KB10.62071519
83MAP3K50.61900322
84PTK20.61469244
85BMX0.61447884
86NTRK20.56913189
87MAPK70.56406661
88CDK90.54589474
89PRKAA20.54327166
90TAOK20.54275244
91AKT20.53811343
92IKBKE0.53763172
93PDGFRB0.52729889
94STK100.52142192
95NUAK10.52057638
96AURKB0.51893674
97BCKDK0.51530692
98CSNK1A1L0.51347072
99LIMK10.51332184
100CDK120.51063081
101PDGFRA0.49656444
102GRK50.47735167
103SGK10.47542109
104ILK0.45733642
105ADRBK10.44526273
106MTOR0.44363264
107TYRO30.42421969
108PRKCI0.41785887
109IRAK40.40089749
110RPS6KA10.39188475
111PKN20.37852143
112HIPK20.37414657
113SIK10.36952180
114FGR0.36846652
115KSR20.36816588
116STK40.36546408
117PAK30.36324867
118ROCK10.35298757
119MAPK110.35182841
120CHUK0.34643272
121STK30.34142431
122DYRK20.33646686
123OXSR10.33207953
124MAP2K20.32384796
125PRKCE0.32122379
126TIE10.31836774
127MELK0.31057746
128MAPK40.30885575
129FLT30.30623036
130ITK0.30444826
131CSK0.30092323
132ERBB40.29856721
133STK38L0.29436177
134WNK30.29032366
135GSK3A0.28516866
136ATM0.28352041
137CDK70.27089705
138CSNK1E0.25964060
139NME20.25929308
140JAK10.24361450
141HCK0.24152192
142ERBB20.24081945
143JAK20.23323739
144PIK3CA0.23183007
145PDK20.23178475
146BMPR1B0.22918365
147STK110.21575113
148PBK0.21299050
149AURKA0.21216043
150CDK30.20986963
151CSNK1D0.20303495
152ROCK20.19652805
153RET0.19356417
154PKN10.19130953
155TBK10.18593731
156STK380.17277745
157SRC0.16063256

Predicted pathways (KEGG)

RankGene SetZ-score
1Linoleic acid metabolism_Homo sapiens_hsa005913.85755591
2alpha-Linolenic acid metabolism_Homo sapiens_hsa005923.81760918
3Fatty acid elongation_Homo sapiens_hsa000623.10837068
4Circadian rhythm_Homo sapiens_hsa047102.93464451
5Cyanoamino acid metabolism_Homo sapiens_hsa004602.88790740
6Arachidonic acid metabolism_Homo sapiens_hsa005902.85168752
7Fat digestion and absorption_Homo sapiens_hsa049752.80684204
8Phenylalanine metabolism_Homo sapiens_hsa003602.31847972
9Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.25806533
10Ether lipid metabolism_Homo sapiens_hsa005652.16453833
11Sphingolipid metabolism_Homo sapiens_hsa006002.15945258
12Histidine metabolism_Homo sapiens_hsa003401.92803886
13VEGF signaling pathway_Homo sapiens_hsa043701.73627889
14Basal cell carcinoma_Homo sapiens_hsa052171.59815944
15Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.58804441
16ECM-receptor interaction_Homo sapiens_hsa045121.52508949
17Tight junction_Homo sapiens_hsa045301.48350251
18GnRH signaling pathway_Homo sapiens_hsa049121.46173176
19Oxidative phosphorylation_Homo sapiens_hsa001901.42285439
20Salivary secretion_Homo sapiens_hsa049701.38505585
21Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.33151721
22Adherens junction_Homo sapiens_hsa045201.29343342
23Proteoglycans in cancer_Homo sapiens_hsa052051.23320962
24Bladder cancer_Homo sapiens_hsa052191.21843445
25Staphylococcus aureus infection_Homo sapiens_hsa051501.20469926
26Tyrosine metabolism_Homo sapiens_hsa003501.15230988
27Melanogenesis_Homo sapiens_hsa049161.14103549
28Phototransduction_Homo sapiens_hsa047441.14025102
29Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.13602437
30Vascular smooth muscle contraction_Homo sapiens_hsa042701.13510471
31Collecting duct acid secretion_Homo sapiens_hsa049661.13473032
32Axon guidance_Homo sapiens_hsa043601.09242323
33Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.08870269
34Pertussis_Homo sapiens_hsa051331.07637981
35Sulfur metabolism_Homo sapiens_hsa009201.03159322
36Hippo signaling pathway_Homo sapiens_hsa043901.02924247
37Amoebiasis_Homo sapiens_hsa051461.01577915
38Ribosome_Homo sapiens_hsa030101.00393205
39Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.00083077
40Choline metabolism in cancer_Homo sapiens_hsa052310.98884783
41Hedgehog signaling pathway_Homo sapiens_hsa043400.98706931
42Leukocyte transendothelial migration_Homo sapiens_hsa046700.96571535
43ABC transporters_Homo sapiens_hsa020100.95190836
44Notch signaling pathway_Homo sapiens_hsa043300.94743991
45Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.93794654
46Retinol metabolism_Homo sapiens_hsa008300.91064725
47Renin secretion_Homo sapiens_hsa049240.90542784
48Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.89845001
49Parkinsons disease_Homo sapiens_hsa050120.89337404
50Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.89261690
51Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.89134081
52Steroid hormone biosynthesis_Homo sapiens_hsa001400.86823479
53Alzheimers disease_Homo sapiens_hsa050100.86597569
54Caffeine metabolism_Homo sapiens_hsa002320.85031213
55Long-term depression_Homo sapiens_hsa047300.84253016
56Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.83632254
57Ras signaling pathway_Homo sapiens_hsa040140.83308397
58Sphingolipid signaling pathway_Homo sapiens_hsa040710.82078781
59Glioma_Homo sapiens_hsa052140.80035435
60Huntingtons disease_Homo sapiens_hsa050160.79926244
61Pancreatic secretion_Homo sapiens_hsa049720.79181667
62Acute myeloid leukemia_Homo sapiens_hsa052210.78893458
63Steroid biosynthesis_Homo sapiens_hsa001000.78014471
64Glutathione metabolism_Homo sapiens_hsa004800.77882557
65Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.77082553
66Dilated cardiomyopathy_Homo sapiens_hsa054140.76502637
67Chemical carcinogenesis_Homo sapiens_hsa052040.75756934
68Gastric acid secretion_Homo sapiens_hsa049710.75447736
69Platelet activation_Homo sapiens_hsa046110.73290968
70Oxytocin signaling pathway_Homo sapiens_hsa049210.73251690
71Toxoplasmosis_Homo sapiens_hsa051450.73205597
72beta-Alanine metabolism_Homo sapiens_hsa004100.73136229
73Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.73057548
74Focal adhesion_Homo sapiens_hsa045100.72652174
75Glycerophospholipid metabolism_Homo sapiens_hsa005640.68446246
76Arginine biosynthesis_Homo sapiens_hsa002200.68325155
77Glycerolipid metabolism_Homo sapiens_hsa005610.66526507
78PPAR signaling pathway_Homo sapiens_hsa033200.64401041
79Protein digestion and absorption_Homo sapiens_hsa049740.64380475
80Hepatitis C_Homo sapiens_hsa051600.63412141
81Thyroid cancer_Homo sapiens_hsa052160.62630600
82Insulin resistance_Homo sapiens_hsa049310.61787714
83Vibrio cholerae infection_Homo sapiens_hsa051100.61102681
84AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.61075136
85Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.60219721
86Rap1 signaling pathway_Homo sapiens_hsa040150.57430124
87Serotonergic synapse_Homo sapiens_hsa047260.56126905
88Salmonella infection_Homo sapiens_hsa051320.54148107
89MicroRNAs in cancer_Homo sapiens_hsa052060.52883996
90Olfactory transduction_Homo sapiens_hsa047400.52617468
91TGF-beta signaling pathway_Homo sapiens_hsa043500.52515710
92Estrogen signaling pathway_Homo sapiens_hsa049150.52500487
93p53 signaling pathway_Homo sapiens_hsa041150.51895347
94Mineral absorption_Homo sapiens_hsa049780.51621836
95Long-term potentiation_Homo sapiens_hsa047200.51433196
96Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.51174661
97Dorso-ventral axis formation_Homo sapiens_hsa043200.50606858
98Tuberculosis_Homo sapiens_hsa051520.49229478
99Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.48751335
100Phosphatidylinositol signaling system_Homo sapiens_hsa040700.48539139
101Malaria_Homo sapiens_hsa051440.46260600
102Wnt signaling pathway_Homo sapiens_hsa043100.45895123
103MAPK signaling pathway_Homo sapiens_hsa040100.45220413
104Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.45023836
105NOD-like receptor signaling pathway_Homo sapiens_hsa046210.45013689
106Proteasome_Homo sapiens_hsa030500.43625441
107Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.42707998
108TNF signaling pathway_Homo sapiens_hsa046680.42533632
109Glucagon signaling pathway_Homo sapiens_hsa049220.41861721
110Regulation of actin cytoskeleton_Homo sapiens_hsa048100.40829867
111ErbB signaling pathway_Homo sapiens_hsa040120.40753639
112Calcium signaling pathway_Homo sapiens_hsa040200.40576629
113Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.40128918
114Adipocytokine signaling pathway_Homo sapiens_hsa049200.39939635
115Fatty acid biosynthesis_Homo sapiens_hsa000610.38803933
116Insulin signaling pathway_Homo sapiens_hsa049100.38262105
117Ovarian steroidogenesis_Homo sapiens_hsa049130.37890748
118Melanoma_Homo sapiens_hsa052180.37242374
119Jak-STAT signaling pathway_Homo sapiens_hsa046300.36821908
120Endocytosis_Homo sapiens_hsa041440.36635821
121RNA polymerase_Homo sapiens_hsa030200.34930539
122Renal cell carcinoma_Homo sapiens_hsa052110.34669284
123Glutamatergic synapse_Homo sapiens_hsa047240.34173556
124Phospholipase D signaling pathway_Homo sapiens_hsa040720.33852095
125Neurotrophin signaling pathway_Homo sapiens_hsa047220.32959777
126Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.28938829
127Sulfur relay system_Homo sapiens_hsa041220.26284939
128Oocyte meiosis_Homo sapiens_hsa041140.21957346
129Influenza A_Homo sapiens_hsa051640.21731889
130Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.21456123
131Arginine and proline metabolism_Homo sapiens_hsa003300.21111429
132Galactose metabolism_Homo sapiens_hsa000520.18628307
133Inositol phosphate metabolism_Homo sapiens_hsa005620.16931967

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