

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.76177918 |
| 2 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 6.56358964 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 6.38449565 |
| 4 | cytidine metabolic process (GO:0046087) | 5.73212783 |
| 5 | cytidine catabolic process (GO:0006216) | 5.73212783 |
| 6 | cytidine deamination (GO:0009972) | 5.73212783 |
| 7 | sequestering of actin monomers (GO:0042989) | 5.68533221 |
| 8 | actin nucleation (GO:0045010) | 5.39162376 |
| 9 | proteasome assembly (GO:0043248) | 5.14391956 |
| 10 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 5.09201476 |
| 11 | negative regulation of stress fiber assembly (GO:0051497) | 4.51209708 |
| 12 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.31473825 |
| 13 | negative regulation of phagocytosis (GO:0050765) | 4.24655593 |
| 14 | cytolysis (GO:0019835) | 3.98648855 |
| 15 | response to interferon-beta (GO:0035456) | 3.91894854 |
| 16 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.85967873 |
| 17 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 3.84011315 |
| 18 | regulation of natural killer cell mediated immunity (GO:0002715) | 3.84011315 |
| 19 | positive regulation of natural killer cell mediated immunity (GO:0002717) | 3.82604783 |
| 20 | ATP synthesis coupled proton transport (GO:0015986) | 3.72887162 |
| 21 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.72887162 |
| 22 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 3.69534468 |
| 23 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.69054626 |
| 24 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.67098748 |
| 25 | cellular response to interferon-beta (GO:0035458) | 3.60529466 |
| 26 | T cell receptor signaling pathway (GO:0050852) | 3.58592677 |
| 27 | protein deneddylation (GO:0000338) | 3.57095493 |
| 28 | negative T cell selection (GO:0043383) | 3.55254086 |
| 29 | positive regulation of natural killer cell mediated cytotoxicity (GO:0045954) | 3.54150037 |
| 30 | positive regulation of lamellipodium assembly (GO:0010592) | 3.53450827 |
| 31 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.53415843 |
| 32 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.51680725 |
| 33 | negative regulation of cell killing (GO:0031342) | 3.50135693 |
| 34 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 3.50135693 |
| 35 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.48177341 |
| 36 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.47402065 |
| 37 | B cell mediated immunity (GO:0019724) | 3.46395102 |
| 38 | protein neddylation (GO:0045116) | 3.44628900 |
| 39 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 3.35383036 |
| 40 | regulation of B cell receptor signaling pathway (GO:0050855) | 3.35281284 |
| 41 | negative regulation of T cell apoptotic process (GO:0070233) | 3.35056361 |
| 42 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.34952851 |
| 43 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.34952851 |
| 44 | negative regulation of actin filament bundle assembly (GO:0032232) | 3.34358563 |
| 45 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.28244707 |
| 46 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.28244707 |
| 47 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.28244707 |
| 48 | mannosylation (GO:0097502) | 3.28165367 |
| 49 | positive regulation of gamma-delta T cell activation (GO:0046645) | 3.27760440 |
| 50 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.26745157 |
| 51 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.26745157 |
| 52 | negative thymic T cell selection (GO:0045060) | 3.26676608 |
| 53 | mitochondrial calcium ion transport (GO:0006851) | 3.26509618 |
| 54 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.26137209 |
| 55 | antigen processing and presentation via MHC class Ib (GO:0002475) | 3.23569686 |
| 56 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.23477082 |
| 57 | cullin deneddylation (GO:0010388) | 3.20398204 |
| 58 | interferon-gamma production (GO:0032609) | 3.16238514 |
| 59 | antigen receptor-mediated signaling pathway (GO:0050851) | 3.13416558 |
| 60 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.07124228 |
| 61 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.07124228 |
| 62 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.06464725 |
| 63 | negative regulation of ligase activity (GO:0051352) | 3.06464725 |
| 64 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.06385797 |
| 65 | regulation of isotype switching to IgG isotypes (GO:0048302) | 3.05746334 |
| 66 | regulation of T cell receptor signaling pathway (GO:0050856) | 3.03995005 |
| 67 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.03933310 |
| 68 | positive regulation of cell killing (GO:0031343) | 3.03571018 |
| 69 | immunoglobulin mediated immune response (GO:0016064) | 2.97851907 |
| 70 | regulation of T cell tolerance induction (GO:0002664) | 2.97485705 |
| 71 | xenobiotic catabolic process (GO:0042178) | 2.97083743 |
| 72 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 2.94824787 |
| 73 | positive regulation of T cell cytokine production (GO:0002726) | 2.94283521 |
| 74 | purine deoxyribonucleotide catabolic process (GO:0009155) | 2.92579420 |
| 75 | piRNA metabolic process (GO:0034587) | 2.92322064 |
| 76 | regulation of cell killing (GO:0031341) | 2.90317983 |
| 77 | chaperone-mediated protein transport (GO:0072321) | 2.88914872 |
| 78 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.87945381 |
| 79 | anterograde synaptic vesicle transport (GO:0048490) | 2.87281554 |
| 80 | respiratory electron transport chain (GO:0022904) | 2.86986998 |
| 81 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.84857714 |
| 82 | positive thymic T cell selection (GO:0045059) | 2.84577782 |
| 83 | T cell migration (GO:0072678) | 2.83724061 |
| 84 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 2.82247384 |
| 85 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.80943560 |
| 86 | negative regulation of viral genome replication (GO:0045071) | 2.80113497 |
| 87 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.79338243 |
| 88 | electron transport chain (GO:0022900) | 2.78623891 |
| 89 | positive regulation of tolerance induction (GO:0002645) | 2.78174927 |
| 90 | vitamin transmembrane transport (GO:0035461) | 2.77855072 |
| 91 | leukocyte aggregation (GO:0070486) | 2.77840792 |
| 92 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.77767428 |
| 93 | estrogen biosynthetic process (GO:0006703) | 2.77510587 |
| 94 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.75875820 |
| 95 | regulation of antigen receptor-mediated signaling pathway (GO:0050854) | 2.75826743 |
| 96 | cellular defense response (GO:0006968) | 2.72194504 |
| 97 | positive regulation of lamellipodium organization (GO:1902745) | 2.70501330 |
| 98 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.70131126 |
| 99 | regulation of gamma-delta T cell differentiation (GO:0045586) | 2.69825369 |
| 100 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.69046738 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 5.68909495 |
| 2 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 4.58308904 |
| 3 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 3.93493702 |
| 4 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.88385287 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.65858134 |
| 6 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 3.17133672 |
| 7 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.08746793 |
| 8 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.07319182 |
| 9 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.94606095 |
| 10 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.94510178 |
| 11 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.82942896 |
| 12 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 2.78147949 |
| 13 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.69118545 |
| 14 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.63000106 |
| 15 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.62939801 |
| 16 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.59411740 |
| 17 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.44219918 |
| 18 | MYB_26560356_Chip-Seq_TH2_Human | 2.23252662 |
| 19 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.21730533 |
| 20 | VDR_22108803_ChIP-Seq_LS180_Human | 2.11094305 |
| 21 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.08596210 |
| 22 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.05632299 |
| 23 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.00226109 |
| 24 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 2.00020283 |
| 25 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.99512350 |
| 26 | GATA3_26560356_Chip-Seq_TH2_Human | 1.96692817 |
| 27 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.93535414 |
| 28 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.87119268 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.83898645 |
| 30 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.83097743 |
| 31 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.80219962 |
| 32 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.78622150 |
| 33 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.75238037 |
| 34 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74372187 |
| 35 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.72926522 |
| 36 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.72163141 |
| 37 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.63166768 |
| 38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.62014699 |
| 39 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.60858620 |
| 40 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.59374283 |
| 41 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.58664612 |
| 42 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.50921772 |
| 43 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.48878504 |
| 44 | UTX_26944678_Chip-Seq_JUKART_Human | 1.45504982 |
| 45 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.44205515 |
| 46 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.43397642 |
| 47 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.41552117 |
| 48 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.37496655 |
| 49 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.32076565 |
| 50 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.29392081 |
| 51 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.27893251 |
| 52 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.25041285 |
| 53 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.22316815 |
| 54 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.20524829 |
| 55 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.20451193 |
| 56 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.20065460 |
| 57 | MYB_26560356_Chip-Seq_TH1_Human | 1.19725788 |
| 58 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.16081585 |
| 59 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.15569277 |
| 60 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13806340 |
| 61 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.12559715 |
| 62 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.09985621 |
| 63 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.09877874 |
| 64 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 1.08805612 |
| 65 | BCL6_27268052_Chip-Seq_Bcells_Human | 1.08316153 |
| 66 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.08216519 |
| 67 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.07176709 |
| 68 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.06235404 |
| 69 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.05602771 |
| 70 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.04743029 |
| 71 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.04740483 |
| 72 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.03312770 |
| 73 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.02768638 |
| 74 | RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.00617780 |
| 75 | P300_27268052_Chip-Seq_Bcells_Human | 1.00066516 |
| 76 | MAF_26560356_Chip-Seq_TH2_Human | 0.99240035 |
| 77 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.98860327 |
| 78 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 0.98630284 |
| 79 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.97996903 |
| 80 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 0.96223636 |
| 81 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.94634060 |
| 82 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 0.93549514 |
| 83 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.93454765 |
| 84 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.93299796 |
| 85 | MAF_26560356_Chip-Seq_TH1_Human | 0.93110022 |
| 86 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.91804245 |
| 87 | AR_20517297_ChIP-Seq_VCAP_Human | 0.91433190 |
| 88 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.88903931 |
| 89 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.88220163 |
| 90 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 0.87924680 |
| 91 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.87122062 |
| 92 | ERA_21632823_ChIP-Seq_H3396_Human | 0.86716505 |
| 93 | SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.86568478 |
| 94 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.86128117 |
| 95 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 0.84949326 |
| 96 | MEIS1_20887958_ChIP-Seq_HPC-7_Mouse | 0.83060673 |
| 97 | OCT4_20526341_ChIP-Seq_ESCs_Human | 0.82253875 |
| 98 | PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.82243141 |
| 99 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.82223670 |
| 100 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.81973590 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 5.31314173 |
| 2 | MP0009785_altered_susceptibility_to | 3.28670056 |
| 3 | MP0001835_abnormal_antigen_presentation | 3.14168991 |
| 4 | MP0003724_increased_susceptibility_to | 2.92799560 |
| 5 | MP0003252_abnormal_bile_duct | 2.78956691 |
| 6 | MP0003763_abnormal_thymus_physiology | 2.68202781 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.59186639 |
| 8 | MP0005025_abnormal_response_to | 2.55749955 |
| 9 | MP0005387_immune_system_phenotype | 2.46272824 |
| 10 | MP0001790_abnormal_immune_system | 2.46272824 |
| 11 | MP0008004_abnormal_stomach_pH | 2.45392506 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 2.38735637 |
| 13 | MP0000685_abnormal_immune_system | 2.33666227 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.33182072 |
| 15 | MP0001800_abnormal_humoral_immune | 2.29870082 |
| 16 | MP0001819_abnormal_immune_cell | 2.29291802 |
| 17 | MP0002723_abnormal_immune_serum | 2.26364462 |
| 18 | MP0009764_decreased_sensitivity_to | 2.14288334 |
| 19 | MP0002138_abnormal_hepatobiliary_system | 2.14212443 |
| 20 | MP0002419_abnormal_innate_immunity | 2.14181751 |
| 21 | MP0003436_decreased_susceptibility_to | 2.13561599 |
| 22 | MP0002452_abnormal_antigen_presenting | 2.09775663 |
| 23 | MP0009333_abnormal_splenocyte_physiolog | 2.05487886 |
| 24 | MP0003011_delayed_dark_adaptation | 2.02405635 |
| 25 | MP0002148_abnormal_hypersensitivity_rea | 2.02058133 |
| 26 | MP0008877_abnormal_DNA_methylation | 1.99989904 |
| 27 | MP0003693_abnormal_embryo_hatching | 1.98424517 |
| 28 | MP0006082_CNS_inflammation | 1.93494845 |
| 29 | MP0005084_abnormal_gallbladder_morpholo | 1.76816588 |
| 30 | MP0002166_altered_tumor_susceptibility | 1.74685729 |
| 31 | MP0008260_abnormal_autophagy | 1.73194090 |
| 32 | MP0000716_abnormal_immune_system | 1.70844350 |
| 33 | MP0003172_abnormal_lysosome_physiology | 1.70302016 |
| 34 | MP0002405_respiratory_system_inflammati | 1.66617259 |
| 35 | MP0002398_abnormal_bone_marrow | 1.65531700 |
| 36 | MP0001845_abnormal_inflammatory_respons | 1.62247812 |
| 37 | MP0002277_abnormal_respiratory_mucosa | 1.55491687 |
| 38 | MP0010155_abnormal_intestine_physiology | 1.50670928 |
| 39 | MP0000689_abnormal_spleen_morphology | 1.50204231 |
| 40 | MP0008058_abnormal_DNA_repair | 1.49485388 |
| 41 | MP0002102_abnormal_ear_morphology | 1.47537014 |
| 42 | MP0000703_abnormal_thymus_morphology | 1.42076090 |
| 43 | MP0001533_abnormal_skeleton_physiology | 1.39811958 |
| 44 | MP0002722_abnormal_immune_system | 1.39178870 |
| 45 | MP0002429_abnormal_blood_cell | 1.34399159 |
| 46 | MP0008469_abnormal_protein_level | 1.33572750 |
| 47 | MP0002876_abnormal_thyroid_physiology | 1.30693024 |
| 48 | MP0005075_abnormal_melanosome_morpholog | 1.29700779 |
| 49 | MP0000465_gastrointestinal_hemorrhage | 1.27779555 |
| 50 | MP0002132_abnormal_respiratory_system | 1.25734081 |
| 51 | MP0005646_abnormal_pituitary_gland | 1.24826020 |
| 52 | MP0001501_abnormal_sleep_pattern | 1.23438804 |
| 53 | MP0001986_abnormal_taste_sensitivity | 1.20793536 |
| 54 | MP0000015_abnormal_ear_pigmentation | 1.20261195 |
| 55 | MP0003880_abnormal_central_pattern | 1.20230361 |
| 56 | MP0003878_abnormal_ear_physiology | 1.18701516 |
| 57 | MP0005377_hearing/vestibular/ear_phenot | 1.18701516 |
| 58 | MP0005085_abnormal_gallbladder_physiolo | 1.18588793 |
| 59 | MP0006072_abnormal_retinal_apoptosis | 1.18082548 |
| 60 | MP0004947_skin_inflammation | 1.17494817 |
| 61 | MP0009763_increased_sensitivity_to | 1.15865321 |
| 62 | MP0002006_tumorigenesis | 1.15763063 |
| 63 | MP0004147_increased_porphyrin_level | 1.14780652 |
| 64 | MP0002653_abnormal_ependyma_morphology | 1.10241557 |
| 65 | MP0001905_abnormal_dopamine_level | 1.08929592 |
| 66 | MP0003866_abnormal_defecation | 1.08700255 |
| 67 | MP0005464_abnormal_platelet_physiology | 1.08064087 |
| 68 | MP0002928_abnormal_bile_duct | 1.04491265 |
| 69 | MP0005645_abnormal_hypothalamus_physiol | 1.03847319 |
| 70 | MP0002736_abnormal_nociception_after | 1.02972597 |
| 71 | MP0004381_abnormal_hair_follicle | 1.00447925 |
| 72 | MP0009765_abnormal_xenobiotic_induced | 0.99875767 |
| 73 | MP0005365_abnormal_bile_salt | 0.99307531 |
| 74 | MP0003045_fibrosis | 0.97782081 |
| 75 | MP0005083_abnormal_biliary_tract | 0.96510329 |
| 76 | MP0001727_abnormal_embryo_implantation | 0.94261101 |
| 77 | MP0008872_abnormal_physiological_respon | 0.92917313 |
| 78 | MP0005379_endocrine/exocrine_gland_phen | 0.91970155 |
| 79 | MP0003448_altered_tumor_morphology | 0.90051732 |
| 80 | MP0002822_catalepsy | 0.89837908 |
| 81 | MP0003806_abnormal_nucleotide_metabolis | 0.89383810 |
| 82 | MP0003786_premature_aging | 0.87703851 |
| 83 | MP0004957_abnormal_blastocyst_morpholog | 0.79606034 |
| 84 | MP0005319_abnormal_enzyme/_coenzyme | 0.78925303 |
| 85 | MP0003075_altered_response_to | 0.78656764 |
| 86 | MP0008995_early_reproductive_senescence | 0.78104313 |
| 87 | MP0002254_reproductive_system_inflammat | 0.76124520 |
| 88 | MP0005636_abnormal_mineral_homeostasis | 0.75760916 |
| 89 | MP0001348_abnormal_lacrimal_gland | 0.74399532 |
| 90 | MP0002163_abnormal_gland_morphology | 0.73378087 |
| 91 | MP0002095_abnormal_skin_pigmentation | 0.72298102 |
| 92 | MP0003950_abnormal_plasma_membrane | 0.70904659 |
| 93 | MP0002837_dystrophic_cardiac_calcinosis | 0.68426209 |
| 94 | MP0003638_abnormal_response/metabolism_ | 0.68008556 |
| 95 | MP0000490_abnormal_crypts_of | 0.67510928 |
| 96 | MP0001346_abnormal_lacrimal_gland | 0.67099164 |
| 97 | MP0001919_abnormal_reproductive_system | 0.65643698 |
| 98 | MP0002019_abnormal_tumor_incidence | 0.64529647 |
| 99 | MP0001542_abnormal_bone_strength | 0.63087158 |
| 100 | MP0000569_abnormal_digit_pigmentation | 0.62912667 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Increased IgM level (HP:0003496) | 6.45314190 |
| 2 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.87626342 |
| 3 | IgG deficiency (HP:0004315) | 4.53694962 |
| 4 | Aplastic anemia (HP:0001915) | 4.07361685 |
| 5 | Eosinophilia (HP:0001880) | 3.82164946 |
| 6 | Abnormality of T cell number (HP:0011839) | 3.61557151 |
| 7 | 3-Methylglutaconic aciduria (HP:0003535) | 3.48928561 |
| 8 | Encephalitis (HP:0002383) | 3.44863745 |
| 9 | Generalized aminoaciduria (HP:0002909) | 3.43948193 |
| 10 | Myositis (HP:0100614) | 3.41095363 |
| 11 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 3.35134291 |
| 12 | T lymphocytopenia (HP:0005403) | 3.23835780 |
| 13 | Abnormality of eosinophils (HP:0001879) | 3.19613439 |
| 14 | Stomatitis (HP:0010280) | 3.08233627 |
| 15 | Bile duct proliferation (HP:0001408) | 3.07567294 |
| 16 | Abnormal biliary tract physiology (HP:0012439) | 3.07567294 |
| 17 | Abnormality of T cells (HP:0002843) | 2.96371940 |
| 18 | Retrobulbar optic neuritis (HP:0100654) | 2.92485581 |
| 19 | Optic neuritis (HP:0100653) | 2.92485581 |
| 20 | Increased intramyocellular lipid droplets (HP:0012240) | 2.92116546 |
| 21 | Mitochondrial inheritance (HP:0001427) | 2.91103336 |
| 22 | Granulocytopenia (HP:0001913) | 2.90483793 |
| 23 | Methylmalonic acidemia (HP:0002912) | 2.87963466 |
| 24 | Hypergammaglobulinemia (HP:0010702) | 2.87553465 |
| 25 | Abnormality of B cell number (HP:0010975) | 2.84510196 |
| 26 | Hepatocellular necrosis (HP:0001404) | 2.83838675 |
| 27 | Lipid accumulation in hepatocytes (HP:0006561) | 2.80678830 |
| 28 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.76860007 |
| 29 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.76860007 |
| 30 | Increased muscle lipid content (HP:0009058) | 2.74268202 |
| 31 | Hepatic necrosis (HP:0002605) | 2.66902460 |
| 32 | Increased hepatocellular lipid droplets (HP:0006565) | 2.65313501 |
| 33 | Autoimmune hemolytic anemia (HP:0001890) | 2.64886741 |
| 34 | Cerebral palsy (HP:0100021) | 2.64041744 |
| 35 | Exertional dyspnea (HP:0002875) | 2.62777222 |
| 36 | IgM deficiency (HP:0002850) | 2.59753000 |
| 37 | Orchitis (HP:0100796) | 2.59151172 |
| 38 | Keratoconjunctivitis sicca (HP:0001097) | 2.57958177 |
| 39 | Abnormality of T cell physiology (HP:0011840) | 2.53952270 |
| 40 | Autoimmune thrombocytopenia (HP:0001973) | 2.51466187 |
| 41 | Anorexia (HP:0002039) | 2.50770391 |
| 42 | Amyotrophic lateral sclerosis (HP:0007354) | 2.49354904 |
| 43 | B lymphocytopenia (HP:0010976) | 2.46867655 |
| 44 | Keratoconjunctivitis (HP:0001096) | 2.46782087 |
| 45 | Chronic diarrhea (HP:0002028) | 2.46115637 |
| 46 | Leukocytosis (HP:0001974) | 2.45046962 |
| 47 | Meningitis (HP:0001287) | 2.42866516 |
| 48 | Hypoproteinemia (HP:0003075) | 2.42628778 |
| 49 | Acute necrotizing encephalopathy (HP:0006965) | 2.42603445 |
| 50 | Severe combined immunodeficiency (HP:0004430) | 2.41825671 |
| 51 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.37273336 |
| 52 | Abnormality of macrophages (HP:0004311) | 2.35100976 |
| 53 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.34990386 |
| 54 | Recurrent cutaneous fungal infections (HP:0011370) | 2.34477537 |
| 55 | Chronic mucocutaneous candidiasis (HP:0002728) | 2.34477537 |
| 56 | Type I transferrin isoform profile (HP:0003642) | 2.33473601 |
| 57 | Abnormality of the aortic arch (HP:0012303) | 2.32810331 |
| 58 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.30321450 |
| 59 | Increased CSF lactate (HP:0002490) | 2.29176534 |
| 60 | Renal Fanconi syndrome (HP:0001994) | 2.25722161 |
| 61 | Recurrent fungal infections (HP:0002841) | 2.19354664 |
| 62 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.18280993 |
| 63 | Dicarboxylic aciduria (HP:0003215) | 2.18280993 |
| 64 | Pustule (HP:0200039) | 2.15032350 |
| 65 | Acute hepatic failure (HP:0006554) | 2.14789271 |
| 66 | Carpal bone hypoplasia (HP:0001498) | 2.11774824 |
| 67 | Facial diplegia (HP:0001349) | 2.10634620 |
| 68 | Pancytopenia (HP:0001876) | 2.08239237 |
| 69 | Methylmalonic aciduria (HP:0012120) | 2.07834317 |
| 70 | Petechiae (HP:0000967) | 2.07736447 |
| 71 | Gangrene (HP:0100758) | 2.07233368 |
| 72 | Aplasia/hypoplasia of the uterus (HP:0008684) | 2.07131189 |
| 73 | Cellular immunodeficiency (HP:0005374) | 2.05129963 |
| 74 | Hypoplasia of the thymus (HP:0000778) | 2.04498534 |
| 75 | Vasculitis (HP:0002633) | 2.03980347 |
| 76 | Hemoptysis (HP:0002105) | 2.03644145 |
| 77 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.02611428 |
| 78 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.02013091 |
| 79 | Lymphoma (HP:0002665) | 1.99814827 |
| 80 | Reduced antithrombin III activity (HP:0001976) | 1.99063546 |
| 81 | Pancreatic cysts (HP:0001737) | 1.98375872 |
| 82 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.97860426 |
| 83 | Neutropenia (HP:0001875) | 1.96648957 |
| 84 | Pulmonary infiltrates (HP:0002113) | 1.96391833 |
| 85 | Keratoconus (HP:0000563) | 1.94021021 |
| 86 | Increased corneal curvature (HP:0100692) | 1.94021021 |
| 87 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.93983725 |
| 88 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.93983725 |
| 89 | Abnormal protein glycosylation (HP:0012346) | 1.93983725 |
| 90 | Abnormal glycosylation (HP:0012345) | 1.93983725 |
| 91 | Abnormal albumin level (HP:0012116) | 1.93768310 |
| 92 | Hypoalbuminemia (HP:0003073) | 1.93768310 |
| 93 | Lymphopenia (HP:0001888) | 1.93494005 |
| 94 | Abolished electroretinogram (ERG) (HP:0000550) | 1.92315438 |
| 95 | Combined immunodeficiency (HP:0005387) | 1.91513642 |
| 96 | Joint swelling (HP:0001386) | 1.91070734 |
| 97 | Chest pain (HP:0100749) | 1.89524257 |
| 98 | Hypochromic anemia (HP:0001931) | 1.88787785 |
| 99 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.88768815 |
| 100 | Severe visual impairment (HP:0001141) | 1.87948965 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 6.85054244 |
| 2 | KDR | 4.58626941 |
| 3 | MAP3K12 | 3.85535526 |
| 4 | TXK | 3.46154255 |
| 5 | TESK1 | 2.91634061 |
| 6 | MAP4K2 | 2.80645574 |
| 7 | LIMK1 | 2.34628076 |
| 8 | MAP4K1 | 2.29747126 |
| 9 | VRK2 | 2.20272569 |
| 10 | TNK2 | 2.18503972 |
| 11 | TLK1 | 2.14344279 |
| 12 | CDK19 | 2.13179034 |
| 13 | GRK6 | 2.08541273 |
| 14 | NUAK1 | 1.95554426 |
| 15 | SIK2 | 1.84903304 |
| 16 | BCKDK | 1.84674647 |
| 17 | SRPK1 | 1.70917353 |
| 18 | MAP3K11 | 1.67494648 |
| 19 | RPS6KA4 | 1.57543647 |
| 20 | TRIM28 | 1.52912130 |
| 21 | BLK | 1.50663657 |
| 22 | ZAP70 | 1.48611974 |
| 23 | MYLK | 1.46289295 |
| 24 | SIK3 | 1.43948138 |
| 25 | MST4 | 1.39530199 |
| 26 | TBK1 | 1.37429120 |
| 27 | BCR | 1.35897564 |
| 28 | OXSR1 | 1.34221639 |
| 29 | MAP3K14 | 1.20131312 |
| 30 | IRAK4 | 1.16456383 |
| 31 | MAP2K6 | 1.13144659 |
| 32 | CCNB1 | 1.13078899 |
| 33 | TSSK6 | 1.11519991 |
| 34 | SCYL2 | 1.10728907 |
| 35 | IKBKB | 1.05523949 |
| 36 | ITK | 1.03946206 |
| 37 | MAPKAPK3 | 1.03832382 |
| 38 | DAPK1 | 0.97471777 |
| 39 | IKBKE | 0.97262725 |
| 40 | BTK | 0.96902407 |
| 41 | STK39 | 0.94153829 |
| 42 | SYK | 0.92765104 |
| 43 | BUB1 | 0.90745874 |
| 44 | ADRBK2 | 0.90601721 |
| 45 | FES | 0.90528572 |
| 46 | GRK7 | 0.85185243 |
| 47 | LCK | 0.82669873 |
| 48 | ACVR1B | 0.82326749 |
| 49 | EIF2AK3 | 0.81247412 |
| 50 | VRK1 | 0.80065806 |
| 51 | TEC | 0.79785530 |
| 52 | CSK | 0.78710231 |
| 53 | RAF1 | 0.73339023 |
| 54 | LYN | 0.70719096 |
| 55 | MARK3 | 0.69385771 |
| 56 | KSR1 | 0.66202066 |
| 57 | PAK6 | 0.62799162 |
| 58 | ILK | 0.62027538 |
| 59 | NEK2 | 0.59533284 |
| 60 | TAOK3 | 0.58973043 |
| 61 | CLK1 | 0.58559416 |
| 62 | NEK1 | 0.56118099 |
| 63 | GRK1 | 0.54524338 |
| 64 | PRKCQ | 0.53794199 |
| 65 | CSF1R | 0.52166612 |
| 66 | MAPK13 | 0.52008758 |
| 67 | MAP3K13 | 0.49559244 |
| 68 | PIM1 | 0.48239215 |
| 69 | FGR | 0.48202484 |
| 70 | STK10 | 0.46520525 |
| 71 | ATR | 0.44170610 |
| 72 | PAK3 | 0.43724700 |
| 73 | JAK3 | 0.40217796 |
| 74 | RPS6KA5 | 0.39292798 |
| 75 | PAK1 | 0.38828417 |
| 76 | ERBB3 | 0.37704152 |
| 77 | MAP2K7 | 0.37389434 |
| 78 | ROCK1 | 0.35258291 |
| 79 | WNK4 | 0.34834240 |
| 80 | MAPKAPK2 | 0.33267072 |
| 81 | HCK | 0.33234528 |
| 82 | PAK4 | 0.33145373 |
| 83 | CHUK | 0.31906929 |
| 84 | WNK3 | 0.31724024 |
| 85 | GRK5 | 0.31582739 |
| 86 | ZAK | 0.30286697 |
| 87 | TRPM7 | 0.29405397 |
| 88 | STK24 | 0.28911177 |
| 89 | TAOK1 | 0.26057721 |
| 90 | STK38L | 0.25934901 |
| 91 | IGF1R | 0.24886035 |
| 92 | BRSK2 | 0.24121536 |
| 93 | CSNK2A1 | 0.23400271 |
| 94 | ABL1 | 0.21315786 |
| 95 | PRKCI | 0.20103801 |
| 96 | AURKB | 0.19658380 |
| 97 | INSR | 0.19348769 |
| 98 | PLK4 | 0.19160030 |
| 99 | STK16 | 0.18458847 |
| 100 | MAPKAPK5 | 0.17503401 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.91604010 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.09244705 |
| 3 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.45238146 |
| 4 | Antigen processing and presentation_Homo sapiens_hsa04612 | 3.18407561 |
| 5 | Allograft rejection_Homo sapiens_hsa05330 | 3.01894499 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.96630806 |
| 7 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.86044004 |
| 8 | Parkinsons disease_Homo sapiens_hsa05012 | 2.55374580 |
| 9 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 2.41632430 |
| 10 | Asthma_Homo sapiens_hsa05310 | 2.25976630 |
| 11 | Protein export_Homo sapiens_hsa03060 | 2.09705700 |
| 12 | Shigellosis_Homo sapiens_hsa05131 | 2.08933422 |
| 13 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.03233011 |
| 14 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.99706349 |
| 15 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.82850015 |
| 16 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.76090695 |
| 17 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.73568859 |
| 18 | Viral myocarditis_Homo sapiens_hsa05416 | 1.69587345 |
| 19 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.68458607 |
| 20 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.64105355 |
| 21 | Huntingtons disease_Homo sapiens_hsa05016 | 1.60565051 |
| 22 | Alzheimers disease_Homo sapiens_hsa05010 | 1.57247428 |
| 23 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.56915674 |
| 24 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.53264382 |
| 25 | RNA polymerase_Homo sapiens_hsa03020 | 1.50533778 |
| 26 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.42222309 |
| 27 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.41610616 |
| 28 | Leishmaniasis_Homo sapiens_hsa05140 | 1.26029285 |
| 29 | Measles_Homo sapiens_hsa05162 | 1.23719204 |
| 30 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 1.19803213 |
| 31 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.19261669 |
| 32 | Salmonella infection_Homo sapiens_hsa05132 | 1.06500422 |
| 33 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.06139182 |
| 34 | Peroxisome_Homo sapiens_hsa04146 | 1.04731186 |
| 35 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.03965956 |
| 36 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.03677963 |
| 37 | Ribosome_Homo sapiens_hsa03010 | 1.02710310 |
| 38 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.01608928 |
| 39 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.93765527 |
| 40 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.92912074 |
| 41 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.89203182 |
| 42 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.85856736 |
| 43 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.85324731 |
| 44 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.79404191 |
| 45 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.78345637 |
| 46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.78142015 |
| 47 | Legionellosis_Homo sapiens_hsa05134 | 0.77551034 |
| 48 | Phototransduction_Homo sapiens_hsa04744 | 0.74238367 |
| 49 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.73788923 |
| 50 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.73681725 |
| 51 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.72464260 |
| 52 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.72453859 |
| 53 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.72004151 |
| 54 | Retinol metabolism_Homo sapiens_hsa00830 | 0.70311180 |
| 55 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.68245309 |
| 56 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.67917275 |
| 57 | Phagosome_Homo sapiens_hsa04145 | 0.66285615 |
| 58 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.64932823 |
| 59 | Pertussis_Homo sapiens_hsa05133 | 0.63468373 |
| 60 | Homologous recombination_Homo sapiens_hsa03440 | 0.63316054 |
| 61 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.63278213 |
| 62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.62561405 |
| 63 | Tuberculosis_Homo sapiens_hsa05152 | 0.61785840 |
| 64 | Purine metabolism_Homo sapiens_hsa00230 | 0.60195844 |
| 65 | Osteoclast differentiation_Homo sapiens_hsa04380 | 0.59563365 |
| 66 | Sulfur relay system_Homo sapiens_hsa04122 | 0.59493204 |
| 67 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.59033909 |
| 68 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.56361846 |
| 69 | Basal transcription factors_Homo sapiens_hsa03022 | 0.55994759 |
| 70 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.55229707 |
| 71 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.54543330 |
| 72 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.52312356 |
| 73 | Spliceosome_Homo sapiens_hsa03040 | 0.51808001 |
| 74 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.50682143 |
| 75 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.50408102 |
| 76 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.50168157 |
| 77 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50011632 |
| 78 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.48941781 |
| 79 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.48775587 |
| 80 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.47783497 |
| 81 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.46553639 |
| 82 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.46143459 |
| 83 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.45477538 |
| 84 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.45094321 |
| 85 | Influenza A_Homo sapiens_hsa05164 | 0.44398901 |
| 86 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.44080125 |
| 87 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.44031508 |
| 88 | Malaria_Homo sapiens_hsa05144 | 0.41145574 |
| 89 | Apoptosis_Homo sapiens_hsa04210 | 0.39808080 |
| 90 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.35091362 |
| 91 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.34173990 |
| 92 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.33999691 |
| 93 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.32509633 |
| 94 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.30701220 |
| 95 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 0.30424482 |
| 96 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.30363828 |
| 97 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.26785613 |
| 98 | RNA degradation_Homo sapiens_hsa03018 | 0.26428139 |
| 99 | Metabolic pathways_Homo sapiens_hsa01100 | 0.25815932 |
| 100 | RNA transport_Homo sapiens_hsa03013 | 0.23158009 |

