CNOT10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)5.29281652
2DNA replication initiation (GO:0006270)4.89172309
3DNA strand elongation involved in DNA replication (GO:0006271)4.83517031
4DNA strand elongation (GO:0022616)4.59275728
5telomere maintenance via semi-conservative replication (GO:0032201)4.55706603
6protein localization to kinetochore (GO:0034501)4.35721212
7nuclear pore organization (GO:0006999)4.30677609
8synapsis (GO:0007129)4.26091293
9DNA double-strand break processing (GO:0000729)4.25275650
10nucleobase biosynthetic process (GO:0046112)4.18497262
11mitotic metaphase plate congression (GO:0007080)4.11186314
12regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.10216251
13mitotic nuclear envelope disassembly (GO:0007077)4.00428528
14IMP biosynthetic process (GO:0006188)3.99006431
15telomere maintenance via recombination (GO:0000722)3.96719833
16mitotic recombination (GO:0006312)3.88061089
17protein localization to chromosome, centromeric region (GO:0071459)3.80686217
18regulation of centriole replication (GO:0046599)3.79886981
19telomere maintenance via telomere lengthening (GO:0010833)3.78319470
20purine nucleobase biosynthetic process (GO:0009113)3.77561471
21nucleotide-excision repair, DNA gap filling (GO:0006297)3.75493881
22replication fork processing (GO:0031297)3.74885102
23DNA replication-dependent nucleosome organization (GO:0034723)3.73903051
24DNA replication-dependent nucleosome assembly (GO:0006335)3.73903051
25membrane disassembly (GO:0030397)3.71031155
26nuclear envelope disassembly (GO:0051081)3.71031155
27somatic diversification of immune receptors via somatic mutation (GO:0002566)3.70890943
28somatic hypermutation of immunoglobulin genes (GO:0016446)3.70890943
29DNA replication checkpoint (GO:0000076)3.69655655
30nuclear pore complex assembly (GO:0051292)3.69309627
31metaphase plate congression (GO:0051310)3.66820075
32proteasome assembly (GO:0043248)3.65456440
33kinetochore organization (GO:0051383)3.64229438
34folic acid-containing compound biosynthetic process (GO:0009396)3.63846165
35mitotic sister chromatid segregation (GO:0000070)3.55103393
36negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.54907178
37translesion synthesis (GO:0019985)3.53719815
38DNA duplex unwinding (GO:0032508)3.47230326
39DNA geometric change (GO:0032392)3.44656619
40DNA catabolic process, exonucleolytic (GO:0000738)3.43847024
41formation of translation preinitiation complex (GO:0001731)3.42194987
42meiotic chromosome segregation (GO:0045132)3.39872299
43ribosome biogenesis (GO:0042254)3.39865637
44kinetochore assembly (GO:0051382)3.39252749
45chromatin remodeling at centromere (GO:0031055)3.38527308
46mitochondrial respiratory chain complex I assembly (GO:0032981)3.36674343
47NADH dehydrogenase complex assembly (GO:0010257)3.36674343
48mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.36674343
49postreplication repair (GO:0006301)3.35956155
50regulation of mitotic spindle checkpoint (GO:1903504)3.35668137
51regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.35668137
52mitotic chromosome condensation (GO:0007076)3.35291048
53histone H2A acetylation (GO:0043968)3.32895460
54attachment of spindle microtubules to kinetochore (GO:0008608)3.30545929
55regulation of helicase activity (GO:0051095)3.30249462
56IMP metabolic process (GO:0046040)3.28895946
57sister chromatid segregation (GO:0000819)3.27465331
58intra-S DNA damage checkpoint (GO:0031573)3.26709534
59CENP-A containing nucleosome assembly (GO:0034080)3.25888286
60maturation of 5.8S rRNA (GO:0000460)3.22634840
61mismatch repair (GO:0006298)3.20567242
62establishment of chromosome localization (GO:0051303)3.19340636
63negative regulation of mRNA processing (GO:0050686)3.19209904
64maturation of SSU-rRNA (GO:0030490)3.17967347
65resolution of meiotic recombination intermediates (GO:0000712)3.17667167
66transcription-coupled nucleotide-excision repair (GO:0006283)3.17523988
67DNA replication-independent nucleosome assembly (GO:0006336)3.16702791
68DNA replication-independent nucleosome organization (GO:0034724)3.16702791
69negative regulation of DNA-dependent DNA replication (GO:2000104)3.16558216
70centriole replication (GO:0007099)3.15766558
71negative regulation of chromosome segregation (GO:0051985)3.14399463
72mitotic sister chromatid cohesion (GO:0007064)3.13614314
73regulation of DNA endoreduplication (GO:0032875)3.11795460
74regulation of gene silencing by RNA (GO:0060966)3.10562176
75regulation of posttranscriptional gene silencing (GO:0060147)3.10562176
76regulation of gene silencing by miRNA (GO:0060964)3.10562176
77negative regulation of mitotic sister chromatid segregation (GO:0033048)3.09863779
78negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.09863779
79negative regulation of sister chromatid segregation (GO:0033046)3.09863779
80negative regulation of mitotic sister chromatid separation (GO:2000816)3.09863779
81recombinational repair (GO:0000725)3.09093765
82negative regulation of RNA splicing (GO:0033119)3.07726781
83double-strand break repair via nonhomologous end joining (GO:0006303)3.07508733
84non-recombinational repair (GO:0000726)3.07508733
85mitotic spindle assembly checkpoint (GO:0007094)3.06539032
86double-strand break repair via homologous recombination (GO:0000724)3.06457039
87pseudouridine synthesis (GO:0001522)3.04913374
88DNA ligation (GO:0006266)3.04804696
89protein localization to chromosome (GO:0034502)3.04504090
90spindle assembly checkpoint (GO:0071173)3.04153504
91spindle checkpoint (GO:0031577)3.03348187
92snRNA processing (GO:0016180)3.02985062
93heterochromatin organization (GO:0070828)3.02693448
94negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.98590059
95regulation of chromosome segregation (GO:0051983)2.98529770
96reciprocal DNA recombination (GO:0035825)2.96124792
97reciprocal meiotic recombination (GO:0007131)2.96124792
98histone exchange (GO:0043486)2.96001505
99spliceosomal snRNP assembly (GO:0000387)2.95703413
100mitotic spindle checkpoint (GO:0071174)2.95692526
101establishment of integrated proviral latency (GO:0075713)2.95658281
102regulation of spindle organization (GO:0090224)2.95411567
103regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.95342440
104peptidyl-arginine omega-N-methylation (GO:0035247)2.94939030
105RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)2.94181755
106telomere maintenance (GO:0000723)2.94096560
107telomere organization (GO:0032200)2.94090685
108mitochondrial respiratory chain complex assembly (GO:0033108)2.93412188
109DNA conformation change (GO:0071103)2.93385562
110nuclear envelope organization (GO:0006998)2.92478868
111regulation of attachment of spindle microtubules to kinetochore (GO:0051988)2.92420635
112mRNA splicing, via spliceosome (GO:0000398)2.91492881
113RNA splicing, via transesterification reactions with bulged adenosine as nucleophile (GO:0000377)2.91492881
114negative regulation of histone methylation (GO:0031061)2.91462690
115protein K6-linked ubiquitination (GO:0085020)2.91282443
116regulation of centrosome duplication (GO:0010824)2.91158002
117DNA synthesis involved in DNA repair (GO:0000731)2.90018649
118RNA splicing, via transesterification reactions (GO:0000375)2.89582087
119exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 2.89323894
120regulation of nuclear cell cycle DNA replication (GO:0033262)2.89033904
121protein complex biogenesis (GO:0070271)2.88975817
122base-excision repair (GO:0006284)2.87470908
123nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)2.87366187
124negative regulation of mRNA metabolic process (GO:1903312)2.87308363
125mitochondrial calcium ion transport (GO:0006851)2.87187907
126maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.86358073
127regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.86151807
128regulation of centrosome cycle (GO:0046605)2.86113711
129ribosome assembly (GO:0042255)2.85698599
130ribonucleoprotein complex biogenesis (GO:0022613)2.84510914
131regulation of histone H3-K9 methylation (GO:0051570)2.84123188
132spliceosomal complex assembly (GO:0000245)2.83961517
133ribosomal small subunit assembly (GO:0000028)2.82732914
134mitochondrial RNA metabolic process (GO:0000959)2.81113071
135regulation of sister chromatid segregation (GO:0033045)2.80380993
136regulation of mitotic sister chromatid separation (GO:0010965)2.80380993
137regulation of mitotic sister chromatid segregation (GO:0033047)2.80380993
138snRNA metabolic process (GO:0016073)2.80351877
139chromosome organization involved in meiosis (GO:0070192)2.79749375
140regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.79442792
141regulation of mitotic metaphase/anaphase transition (GO:0030071)2.78734772
142protein complex localization (GO:0031503)2.77381998

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human9.82726464
2FOXM1_23109430_ChIP-Seq_U2OS_Human4.34589772
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.06978506
4E2F4_17652178_ChIP-ChIP_JURKAT_Human3.78952963
5* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.26749220
6FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human3.13340427
7* MYC_19079543_ChIP-ChIP_MESCs_Mouse3.09718221
8MYC_19030024_ChIP-ChIP_MESCs_Mouse2.78554219
9KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human2.76665736
10* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.67568368
11HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.62310701
12JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.51325735
13EST1_17652178_ChIP-ChIP_JURKAT_Human2.50782674
14ETS1_20019798_ChIP-Seq_JURKAT_Human2.47237568
15MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.42357800
16NELFA_20434984_ChIP-Seq_ESCs_Mouse2.29870966
17XRN2_22483619_ChIP-Seq_HELA_Human2.29199822
18CREB1_15753290_ChIP-ChIP_HEK293T_Human2.25577770
19* GABP_17652178_ChIP-ChIP_JURKAT_Human2.19263057
20* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.13048138
21RBPJ_22232070_ChIP-Seq_NCS_Mouse2.08812347
22* MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.06863185
23CIITA_25753668_ChIP-Seq_RAJI_Human2.05520850
24* E2F1_21310950_ChIP-Seq_MCF-7_Human2.05254529
25CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.99809839
26THAP11_20581084_ChIP-Seq_MESCs_Mouse1.95457294
27AR_21909140_ChIP-Seq_LNCAP_Human1.94916551
28EWS_26573619_Chip-Seq_HEK293_Human1.94877752
29* POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.94744773
30IGF1R_20145208_ChIP-Seq_DFB_Human1.93353949
31EGR1_19374776_ChIP-ChIP_THP-1_Human1.93212465
32MYCN_18555785_ChIP-Seq_MESCs_Mouse1.92793607
33* VDR_23849224_ChIP-Seq_CD4+_Human1.92165893
34* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.89858642
35E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.89600977
36ZNF274_21170338_ChIP-Seq_K562_Hela1.88494279
37VDR_22108803_ChIP-Seq_LS180_Human1.85353534
38* YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.82961939
39* FOXP3_21729870_ChIP-Seq_TREG_Human1.82601427
40* GABP_19822575_ChIP-Seq_HepG2_Human1.81104363
41* NANOG_18555785_ChIP-Seq_MESCs_Mouse1.76637218
42TTF2_22483619_ChIP-Seq_HELA_Human1.72281057
43PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.67415635
44ZFX_18555785_ChIP-Seq_MESCs_Mouse1.67191339
45ELF1_17652178_ChIP-ChIP_JURKAT_Human1.67128629
46NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.66750925
47DCP1A_22483619_ChIP-Seq_HELA_Human1.65614391
48SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.64937329
49CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.64287956
50ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.63476055
51HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.62032182
52MYC_22102868_ChIP-Seq_BL_Human1.61747642
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.61177191
54* SOX2_18555785_ChIP-Seq_MESCs_Mouse1.59515727
55HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human1.49692359
56POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.48994685
57FUS_26573619_Chip-Seq_HEK293_Human1.48859080
58KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.45207810
59KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.45207810
60KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.45207810
61IRF1_19129219_ChIP-ChIP_H3396_Human1.45206279
62KDM5A_27292631_Chip-Seq_BREAST_Human1.42759454
63SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.38857471
64POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.37014099
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.35880789
66POU3F2_20337985_ChIP-ChIP_501MEL_Human1.35326715
67ESR1_15608294_ChIP-ChIP_MCF-7_Human1.35028789
68NOTCH1_21737748_ChIP-Seq_TLL_Human1.34364015
69TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.32222116
70FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.32183603
71* CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.29838909
72ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.29588683
73KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.27116812
74TP63_19390658_ChIP-ChIP_HaCaT_Human1.27020277
75* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.22032100
76* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.20854575
77* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.19975836
78E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.18934679
79TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.15615747
80MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.15228614
81NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.15053045
82STAT3_1855785_ChIP-Seq_MESCs_Mouse1.14939146
83PADI4_21655091_ChIP-ChIP_MCF-7_Human1.14835015
84DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.13968346
85TFEB_21752829_ChIP-Seq_HELA_Human1.13130135
86DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.12998529
87ELK1_19687146_ChIP-ChIP_HELA_Human1.12720120
88* NANOG_21062744_ChIP-ChIP_HESCs_Human1.10141969
89PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.07593255
90PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.06403212
91HOXB4_20404135_ChIP-ChIP_EML_Mouse1.04006134
92SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.03686813
93CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.03171174
94TCF3_18692474_ChIP-Seq_MEFs_Mouse1.00776002
95CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.00482399
96* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.00216841
97TAF15_26573619_Chip-Seq_HEK293_Human0.98266510
98TP53_22573176_ChIP-Seq_HFKS_Human0.96899263
99* SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.96276518
100MYC_18940864_ChIP-ChIP_HL60_Human0.95818883
101TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse0.94463626
102KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.94025336
103ERG_20887958_ChIP-Seq_HPC-7_Mouse0.93866710
104SRF_21415370_ChIP-Seq_HL-1_Mouse0.93849170
105TCF3_18692474_ChIP-Seq_MESCs_Mouse0.90105685
106FLI1_27457419_Chip-Seq_LIVER_Mouse0.89364449
107CEBPA_23403033_ChIP-Seq_LIVER_Mouse0.89139138
108EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.88200015
109SALL1_21062744_ChIP-ChIP_HESCs_Human0.88194232
110SOX2_16153702_ChIP-ChIP_HESCs_Human0.87739390
111VDR_21846776_ChIP-Seq_THP-1_Human0.85136738
112NANOG_16153702_ChIP-ChIP_HESCs_Human0.85057734
113ER_23166858_ChIP-Seq_MCF-7_Human0.83988738
114ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.83913909
115POU5F1_16153702_ChIP-ChIP_HESCs_Human0.83548943
116ASXL1_24218140_ChIP-Seq_BMDM_Mouse0.82514926
117* SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.82060558
118MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.81910354
119BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.81783150
120PKCTHETA_26484144_Chip-Seq_BREAST_Human0.81519969
121SOX2_18692474_ChIP-Seq_MEFs_Mouse0.81076335
122* SOX2_18692474_ChIP-Seq_MESCs_Mouse0.80509147
123CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.77856857
124GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.74742126
125GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.73164229
126CHD7_19251738_ChIP-ChIP_MESCs_Mouse0.72304191
127RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.71712097
128HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.71696198
129GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.69037890
130P300_19829295_ChIP-Seq_ESCs_Human0.68386530

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.85884189
2MP0010094_abnormal_chromosome_stability4.71971492
3MP0003111_abnormal_nucleus_morphology4.01852508
4MP0004957_abnormal_blastocyst_morpholog3.98579565
5MP0008057_abnormal_DNA_replication3.92882149
6MP0008058_abnormal_DNA_repair3.75576122
7MP0003077_abnormal_cell_cycle3.60469037
8MP0008877_abnormal_DNA_methylation3.09194409
9MP0008007_abnormal_cellular_replicative2.92995401
10MP0003123_paternal_imprinting2.77682741
11MP0008932_abnormal_embryonic_tissue2.36495165
12MP0002009_preneoplasia2.35479775
13MP0001730_embryonic_growth_arrest2.33513416
14MP0000350_abnormal_cell_proliferation2.23402741
15MP0009697_abnormal_copulation2.17109495
16MP0010352_gastrointestinal_tract_polyps2.06254161
17MP0003786_premature_aging2.04370261
18MP0002653_abnormal_ependyma_morphology2.03564624
19MP0003283_abnormal_digestive_organ1.93574656
20MP0003136_yellow_coat_color1.84689657
21MP0003121_genomic_imprinting1.82088983
22MP0002085_abnormal_embryonic_tissue1.81981691
23MP0001672_abnormal_embryogenesis/_devel1.81551064
24MP0005380_embryogenesis_phenotype1.81551064
25MP0001697_abnormal_embryo_size1.80198831
26MP0010307_abnormal_tumor_latency1.77360647
27MP0004197_abnormal_fetal_growth/weight/1.73886439
28MP0002084_abnormal_developmental_patter1.73419435
29MP0003119_abnormal_digestive_system1.73122079
30MP0000372_irregular_coat_pigmentation1.72791410
31MP0002210_abnormal_sex_determination1.65636169
32MP0006035_abnormal_mitochondrial_morpho1.63908229
33MP0002080_prenatal_lethality1.63481307
34MP0003890_abnormal_embryonic-extraembry1.63102661
35MP0001293_anophthalmia1.62078286
36MP0002160_abnormal_reproductive_system1.60859015
37MP0003806_abnormal_nucleotide_metabolis1.60121570
38MP0003984_embryonic_growth_retardation1.55375842
39MP0002088_abnormal_embryonic_growth/wei1.53938849
40MP0002396_abnormal_hematopoietic_system1.50783711
41MP0005253_abnormal_eye_physiology1.50458676
42MP0004133_heterotaxia1.48971338
43MP0002938_white_spotting1.47056703
44MP0006292_abnormal_olfactory_placode1.43522321
45MP0001145_abnormal_male_reproductive1.41690578
46MP0006036_abnormal_mitochondrial_physio1.41685460
47MP0003787_abnormal_imprinting1.40403493
48MP0001929_abnormal_gametogenesis1.35148137
49MP0000313_abnormal_cell_death1.29974030
50MP0002086_abnormal_extraembryonic_tissu1.29004700
51MP0003186_abnormal_redox_activity1.28070593
52MP0001764_abnormal_homeostasis1.27546140
53MP0001529_abnormal_vocalization1.26030301
54MP0004808_abnormal_hematopoietic_stem1.23658297
55MP0003646_muscle_fatigue1.22727973
56MP0008789_abnormal_olfactory_epithelium1.20017895
57MP0003941_abnormal_skin_development1.19348249
58MP0000653_abnormal_sex_gland1.16168217
59MP0000678_abnormal_parathyroid_gland1.11195663
60MP0005389_reproductive_system_phenotype1.09605793
61MP0010030_abnormal_orbit_morphology1.07600343
62MP0002095_abnormal_skin_pigmentation1.06643614
63MP0006072_abnormal_retinal_apoptosis1.06505205
64MP0009053_abnormal_anal_canal1.06237986
65MP0005551_abnormal_eye_electrophysiolog1.05139722
66MP0002249_abnormal_larynx_morphology1.04758620
67MP0006276_abnormal_autonomic_nervous1.04503695
68MP0003122_maternal_imprinting1.03730462
69MP0005076_abnormal_cell_differentiation1.01970146
70MP0002019_abnormal_tumor_incidence1.01486834
71MP0003567_abnormal_fetal_cardiomyocyte1.01306668
72MP0003115_abnormal_respiratory_system1.01178987
73MP0000490_abnormal_crypts_of1.00087684
74MP0000427_abnormal_hair_cycle0.99331287
75MP0000049_abnormal_middle_ear0.97036159
76MP0000428_abnormal_craniofacial_morphol0.96981129
77MP0003698_abnormal_male_reproductive0.95073526
78MP0005174_abnormal_tail_pigmentation0.94688252
79MP0000537_abnormal_urethra_morphology0.94663569
80MP0002111_abnormal_tail_morphology0.94351812
81MP0009672_abnormal_birth_weight0.94158754
82MP0000703_abnormal_thymus_morphology0.91539599
83MP0005367_renal/urinary_system_phenotyp0.90999563
84MP0000516_abnormal_urinary_system0.90999563
85MP0003861_abnormal_nervous_system0.90575628
86MP0009703_decreased_birth_body0.89577998
87MP0002638_abnormal_pupillary_reflex0.88861625
88MP0008995_early_reproductive_senescence0.88231553
89MP0000015_abnormal_ear_pigmentation0.87588810
90MP0000371_diluted_coat_color0.84989658
91MP0004147_increased_porphyrin_level0.84745546
92MP0004043_abnormal_pH_regulation0.83845570
93MP0002837_dystrophic_cardiac_calcinosis0.82724358
94MP0003315_abnormal_perineum_morphology0.82262502
95MP0000631_abnormal_neuroendocrine_gland0.81791273
96MP0000647_abnormal_sebaceous_gland0.81497806
97MP0002092_abnormal_eye_morphology0.80797460
98MP0005499_abnormal_olfactory_system0.80548193
99MP0005394_taste/olfaction_phenotype0.80548193
100MP0002697_abnormal_eye_size0.80452446
101MP0002102_abnormal_ear_morphology0.80069092
102MP0005645_abnormal_hypothalamus_physiol0.79759194
103MP0003935_abnormal_craniofacial_develop0.79366029
104MP0001661_extended_life_span0.78279786
105MP0000358_abnormal_cell_content/0.78102935
106MP0002114_abnormal_axial_skeleton0.77081344
107MP0003195_calcinosis0.76939862
108MP0001119_abnormal_female_reproductive0.76820263
109MP0005384_cellular_phenotype0.76306641
110MP0002234_abnormal_pharynx_morphology0.76107266
111MP0003937_abnormal_limbs/digits/tail_de0.75215177
112MP0000569_abnormal_digit_pigmentation0.74532319
113MP0009278_abnormal_bone_marrow0.73996256
114MP0002877_abnormal_melanocyte_morpholog0.73953077
115MP0002075_abnormal_coat/hair_pigmentati0.73523651
116MP0003763_abnormal_thymus_physiology0.73482935
117MP0002751_abnormal_autonomic_nervous0.73474031
118MP0005410_abnormal_fertilization0.73425723
119MP0001286_abnormal_eye_development0.72861573
120MP0005075_abnormal_melanosome_morpholog0.71961564
121MP0003385_abnormal_body_wall0.71415450
122MP0003943_abnormal_hepatobiliary_system0.71013029
123MP0005084_abnormal_gallbladder_morpholo0.70668588
124MP0001727_abnormal_embryo_implantation0.70358482
125MP0002161_abnormal_fertility/fecundity0.70231924
126MP0003718_maternal_effect0.70123346
127MP0000432_abnormal_head_morphology0.69582282
128MP0002116_abnormal_craniofacial_bone0.69010346
129MP0000534_abnormal_ureter_morphology0.68410239
130MP0004264_abnormal_extraembryonic_tissu0.68069673
131MP0002233_abnormal_nose_morphology0.67247840
132MP0004233_abnormal_muscle_weight0.66571465
133MP0001919_abnormal_reproductive_system0.66448545
134MP0005171_absent_coat_pigmentation0.66048048
135MP0005621_abnormal_cell_physiology0.65463467
136MP0005391_vision/eye_phenotype0.65050411
137MP0002163_abnormal_gland_morphology0.64515325
138MP0001324_abnormal_eye_pigmentation0.64336834
139MP0003942_abnormal_urinary_system0.64276555
140MP0003755_abnormal_palate_morphology0.63989377
141MP0003699_abnormal_female_reproductive0.62758609

Predicted human phenotypes

RankGene SetZ-score
1Ependymoma (HP:0002888)4.27455608
2Birth length less than 3rd percentile (HP:0003561)3.81720782
3Selective tooth agenesis (HP:0001592)3.74986463
4Medulloblastoma (HP:0002885)3.56849542
5Colon cancer (HP:0003003)3.48995237
6Pancreatic cysts (HP:0001737)3.09456888
7Breast hypoplasia (HP:0003187)3.02796509
8Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.96367223
9Abnormality of alanine metabolism (HP:0010916)2.96367223
10Hyperalaninemia (HP:0003348)2.96367223
11Supernumerary spleens (HP:0009799)2.96302620
12Chromsome breakage (HP:0040012)2.95797304
1311 pairs of ribs (HP:0000878)2.93624259
14Meckel diverticulum (HP:0002245)2.89733072
15Abnormality of the labia minora (HP:0012880)2.89059000
16Chromosomal breakage induced by crosslinking agents (HP:0003221)2.88355572
17Astrocytoma (HP:0009592)2.87253469
18Abnormality of the astrocytes (HP:0100707)2.87253469
19Abnormality of DNA repair (HP:0003254)2.86870578
20Abnormality of the anterior horn cell (HP:0006802)2.81626069
21Degeneration of anterior horn cells (HP:0002398)2.81626069
22Abnormality of the ileum (HP:0001549)2.80560400
23Reticulocytopenia (HP:0001896)2.78965045
24Missing ribs (HP:0000921)2.76784887
25Abnormality of chromosome stability (HP:0003220)2.75763571
26Patellar aplasia (HP:0006443)2.72234566
27Oral leukoplakia (HP:0002745)2.70582834
28Rhabdomyosarcoma (HP:0002859)2.69396014
29Pancreatic fibrosis (HP:0100732)2.69355808
30Abnormal number of incisors (HP:0011064)2.68045648
31Aplasia/Hypoplasia of the uvula (HP:0010293)2.67749131
32Nephroblastoma (Wilms tumor) (HP:0002667)2.66899513
33Aplasia/Hypoplasia of the patella (HP:0006498)2.51478317
34Abnormality of the preputium (HP:0100587)2.51008858
35Duodenal stenosis (HP:0100867)2.47844766
36Small intestinal stenosis (HP:0012848)2.47844766
37Neoplasm of the pancreas (HP:0002894)2.47421608
38Embryonal renal neoplasm (HP:0011794)2.46815446
39Absent radius (HP:0003974)2.45769351
40Esophageal atresia (HP:0002032)2.45311376
41Cerebral hypomyelination (HP:0006808)2.42988073
42True hermaphroditism (HP:0010459)2.41630344
43Impulsivity (HP:0100710)2.41608792
44Facial cleft (HP:0002006)2.40877492
45Agnosia (HP:0010524)2.39760912
46Acute encephalopathy (HP:0006846)2.38218000
47Abnormality of midbrain morphology (HP:0002418)2.38159442
48Molar tooth sign on MRI (HP:0002419)2.38159442
49Glioma (HP:0009733)2.36748491
50Type I transferrin isoform profile (HP:0003642)2.35981073
51Lipid accumulation in hepatocytes (HP:0006561)2.34213613
52Hypoplasia of the pons (HP:0012110)2.34067034
53Nephronophthisis (HP:0000090)2.32922616
54Abnormality of the duodenum (HP:0002246)2.32552214
55Increased CSF lactate (HP:0002490)2.32506711
56Aplastic anemia (HP:0001915)2.30100237
57Aplasia/Hypoplasia of the sternum (HP:0006714)2.29698030
58Sloping forehead (HP:0000340)2.25953827
59Renal cortical cysts (HP:0000803)2.25914671
60Aplasia involving forearm bones (HP:0009822)2.25898690
61Absent forearm bone (HP:0003953)2.25898690
62Abnormal lung lobation (HP:0002101)2.25776622
63Increased hepatocellular lipid droplets (HP:0006565)2.24122849
64Biliary tract neoplasm (HP:0100574)2.22556134
65Microretrognathia (HP:0000308)2.22099493
66Intestinal atresia (HP:0011100)2.21568914
67Increased nuchal translucency (HP:0010880)2.21249918
68Neoplasm of the oral cavity (HP:0100649)2.20524855
69Ectopic kidney (HP:0000086)2.20510542
70Abnormal protein glycosylation (HP:0012346)2.19704744
71Abnormal glycosylation (HP:0012345)2.19704744
72Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.19704744
73Abnormal protein N-linked glycosylation (HP:0012347)2.19704744
74Acute necrotizing encephalopathy (HP:0006965)2.19697867
75Carpal bone hypoplasia (HP:0001498)2.19387281
76Bone marrow hypocellularity (HP:0005528)2.19267567
77Neoplasm of striated muscle (HP:0009728)2.18593805
78Homocystinuria (HP:0002156)2.18474986
79Abnormality of homocysteine metabolism (HP:0010919)2.18474986
80Rough bone trabeculation (HP:0100670)2.17956326
81Absent thumb (HP:0009777)2.17333482
82Abnormality of the renal cortex (HP:0011035)2.17282207
83Abnormality of the pons (HP:0007361)2.15607066
84Myelodysplasia (HP:0002863)2.14757422
85Volvulus (HP:0002580)2.12151836
86Cafe-au-lait spot (HP:0000957)2.11856301
87Proximal placement of thumb (HP:0009623)2.11233162
88Basal cell carcinoma (HP:0002671)2.08985049
89Abnormality of serum amino acid levels (HP:0003112)2.08743799
90Pancreatic islet-cell hyperplasia (HP:0004510)2.06924355
91Horseshoe kidney (HP:0000085)2.06734951
92Gastrointestinal atresia (HP:0002589)2.06303259
93Medial flaring of the eyebrow (HP:0010747)2.05169874
94Increased serum lactate (HP:0002151)2.05111082
95Increased serum pyruvate (HP:0003542)2.04283255
96Mitochondrial inheritance (HP:0001427)2.02640598
97Broad distal phalanx of finger (HP:0009836)2.02533377
98Abnormal mitochondria in muscle tissue (HP:0008316)2.01949171
99Cortical dysplasia (HP:0002539)2.01816595
100Poikiloderma (HP:0001029)2.01136234
101Prominent metopic ridge (HP:0005487)2.00995059
102Deviation of the thumb (HP:0009603)2.00130969
103Neuroendocrine neoplasm (HP:0100634)1.99175897
104Tracheoesophageal fistula (HP:0002575)1.97916236
105Pheochromocytoma (HP:0002666)1.97084711
106Sclerocornea (HP:0000647)1.95843556
107Neoplasm of the colon (HP:0100273)1.95478882
108Abnormality of the renal medulla (HP:0100957)1.95089745
109High pitched voice (HP:0001620)1.94431800
110Aplasia/Hypoplasia of the spleen (HP:0010451)1.93982629
111Asplenia (HP:0001746)1.92514265
112Cellular immunodeficiency (HP:0005374)1.91818260
113Cerebral edema (HP:0002181)1.90762583
114Abnormality of the metopic suture (HP:0005556)1.90239470
115Pendular nystagmus (HP:0012043)1.90207812
116Abnormality of glycolysis (HP:0004366)1.90047009
117Abnormality of the carotid arteries (HP:0005344)1.89201462
118Hepatic necrosis (HP:0002605)1.89177848
119Prominent nose (HP:0000448)1.89174897
120Hyperglycinemia (HP:0002154)1.88610235
121Clubbing of toes (HP:0100760)1.87855005
122Atresia of the external auditory canal (HP:0000413)1.87485840
123Neoplasm of the rectum (HP:0100743)1.87345301
124Trismus (HP:0000211)1.87147374
125Hepatocellular necrosis (HP:0001404)1.87004881
126Triphalangeal thumb (HP:0001199)1.86981871
127Lactic acidosis (HP:0003128)1.85703616
128Premature graying of hair (HP:0002216)1.83807353
129Ovarian neoplasm (HP:0100615)1.83700321
130Preaxial hand polydactyly (HP:0001177)1.83536931
131Renal duplication (HP:0000075)1.82419927
132Type II lissencephaly (HP:0007260)1.82262707
133Postaxial foot polydactyly (HP:0001830)1.82028155
134Chronic hepatic failure (HP:0100626)1.81251290
135Retinal dysplasia (HP:0007973)1.80241734
136Adenoma sebaceum (HP:0009720)1.80086367
137Angiofibromas (HP:0010615)1.80086367
138Duplicated collecting system (HP:0000081)1.79895082
139Abnormal number of erythroid precursors (HP:0012131)1.79451004
140Rib fusion (HP:0000902)1.78240615
141Abnormality of cells of the erythroid lineage (HP:0012130)1.78142162
142Pelvic girdle muscle weakness (HP:0003749)1.77307690
143Chronic bronchitis (HP:0004469)1.76960267
144Methylmalonic acidemia (HP:0002912)1.76205095
145Abnormality of abdominal situs (HP:0011620)1.75034446
146Abdominal situs inversus (HP:0003363)1.75034446
147Deep palmar crease (HP:0006191)1.74692327
148Shoulder girdle muscle weakness (HP:0003547)1.73619321
149Spinal muscular atrophy (HP:0007269)1.73418080
150Lissencephaly (HP:0001339)1.73412882
151Progressive macrocephaly (HP:0004481)1.73411072
152Hyperglycinuria (HP:0003108)1.72980364
153Freckling (HP:0001480)1.72966663
154Abnormality of the renal collecting system (HP:0004742)1.72570593
155Abnormality of methionine metabolism (HP:0010901)1.68863520
156Dandy-Walker malformation (HP:0001305)1.68402517
157Inability to walk (HP:0002540)1.67294193
158Anencephaly (HP:0002323)1.66559226
159Absent rod-and cone-mediated responses on ERG (HP:0007688)1.64496647
160Aganglionic megacolon (HP:0002251)1.64439527
161Pancytopenia (HP:0001876)1.64055023
162Abnormality of serine family amino acid metabolism (HP:0010894)1.63724513
163Abnormality of glycine metabolism (HP:0010895)1.63724513
164Aplasia/Hypoplasia of the tongue (HP:0010295)1.63601003
165Tubulointerstitial nephritis (HP:0001970)1.63577104
166Multicystic kidney dysplasia (HP:0000003)1.63498279
167Congenital primary aphakia (HP:0007707)1.62920252

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CDC75.00380627
2BUB14.86735709
3WEE14.19615663
4PASK2.88974178
5NEK22.84958967
6TTK2.82218674
7TSSK62.60136914
8VRK22.51999160
9SRPK12.45702193
10BMPR1B2.43722684
11NEK12.30307710
12MST42.29597416
13NUAK12.26907899
14CDK122.24775979
15TRIM282.21145568
16STK162.12966098
17EEF2K2.02776055
18ATR2.02301772
19PLK11.99631795
20EIF2AK11.96339828
21MAP3K101.90184037
22ACVR1B1.89460957
23TLK11.80993499
24PBK1.79554647
25CDK71.79079126
26BRD41.76808261
27MKNK11.76006307
28CCNB11.73674347
29BCR1.70278149
30RPS6KB21.70023940
31CHEK21.62564892
32AURKA1.56901145
33MKNK21.53995936
34STK31.50868423
35BRSK21.50621572
36AURKB1.50613979
37CHEK11.43339735
38PNCK1.43221624
39TGFBR11.42532845
40PLK31.41651079
41VRK11.35505451
42MAP4K21.29301257
43BRSK11.25783847
44FRK1.24999386
45FLT31.24914678
46CDK41.23886323
47AKT31.23248474
48DYRK31.20844211
49BRAF1.19166032
50EIF2AK21.16518389
51RPS6KA41.15466748
52MAP3K81.12749513
53ERBB31.12711859
54SIK31.11629763
55PKN21.07783645
56TAF11.06932308
57CDK21.04689871
58ATM1.02544138
59CLK11.02304845
60PINK11.00447122
61EIF2AK30.99167819
62MAP3K40.98614724
63TNIK0.96769996
64CDK80.94512027
65WNK40.91605374
66SCYL20.90192079
67CSNK1G30.88130911
68PRKCI0.86870129
69CSNK1G10.85586157
70EPHA20.85583999
71PLK40.83219426
72BCKDK0.83073713
73CDK10.82771912
74NME20.79843078
75ALK0.79717140
76MELK0.79181098
77MAPK150.77342581
78STK38L0.76650011
79PDK40.76039649
80PDK30.76039649
81CSNK1A1L0.75265985
82CSNK1G20.75107355
83KSR10.74540939
84CDK30.72819468
85CSNK2A20.71212826
86MAPK130.70124825
87TESK20.69878320
88PAK40.69679999
89ADRBK20.65917245
90GRK10.65820210
91MAP2K70.65714972
92PLK20.65293621
93MAP2K20.63697148
94MAPKAPK30.61484624
95CSNK2A10.59932407
96TEC0.59897056
97OXSR10.59841221
98PRKDC0.59743868
99MTOR0.59286223
100MUSK0.58943275
101INSRR0.58047974
102TAOK30.58036029
103STK100.57612322
104MARK30.56651047
105CSNK1E0.56435993
106STK390.55921372
107STK40.54593613
108DYRK20.48327848
109PAK10.46551940
110NME10.42368414
111PIM10.41608789
112MAPK140.40171846
113CSNK1D0.38531516
114MAP4K10.37877469
115UHMK10.37364675
116LATS10.36941290
117GSK3B0.33744418
118CDK11A0.33316398
119RPS6KB10.31570763
120MAPKAPK50.31305984
121RAF10.30978812
122CDK180.30660571
123CDK150.30273032
124MAP3K30.29690822
125PDGFRA0.29388038
126ZAK0.29044986
127PAK20.28746046
128YES10.28307418
129CSNK1A10.27152218
130MAPK10.25456483
131MAP3K20.25347042
132MAP2K30.23801551
133FGFR10.23697545
134NEK60.23664177
135DAPK10.23304136
136RPS6KA50.22813086
137MAPK90.22693222
138DYRK1B0.21972594
139PDK20.21049608
140WNK30.20910798

Predicted pathways (KEGG)

RankGene SetZ-score
1DNA replication_Homo sapiens_hsa030305.33755889
2Mismatch repair_Homo sapiens_hsa034304.84719917
3Spliceosome_Homo sapiens_hsa030403.46099524
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.43650579
5Base excision repair_Homo sapiens_hsa034103.28132802
6Nucleotide excision repair_Homo sapiens_hsa034203.26385969
7Homologous recombination_Homo sapiens_hsa034403.22665224
8RNA transport_Homo sapiens_hsa030133.13945620
9Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009703.02096472
10Cell cycle_Homo sapiens_hsa041102.93025070
11Fanconi anemia pathway_Homo sapiens_hsa034602.69050005
12One carbon pool by folate_Homo sapiens_hsa006702.66682105
13RNA polymerase_Homo sapiens_hsa030202.66616257
14Non-homologous end-joining_Homo sapiens_hsa034502.33439196
15Ribosome_Homo sapiens_hsa030102.27407295
16Pyrimidine metabolism_Homo sapiens_hsa002402.26009937
17Basal transcription factors_Homo sapiens_hsa030222.12495513
18mRNA surveillance pathway_Homo sapiens_hsa030152.05938690
19* RNA degradation_Homo sapiens_hsa030182.00678645
20Propanoate metabolism_Homo sapiens_hsa006401.99603245
21Proteasome_Homo sapiens_hsa030501.79734832
22Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.63571047
23Oxidative phosphorylation_Homo sapiens_hsa001901.57275266
24Parkinsons disease_Homo sapiens_hsa050121.56516400
25Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.56020144
26Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.48374042
27Oocyte meiosis_Homo sapiens_hsa041141.40965624
28Fatty acid elongation_Homo sapiens_hsa000621.34547569
29Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.31712157
30p53 signaling pathway_Homo sapiens_hsa041151.30938591
31Purine metabolism_Homo sapiens_hsa002301.28318306
32Sulfur relay system_Homo sapiens_hsa041221.24048285
33Butanoate metabolism_Homo sapiens_hsa006501.22845472
34Steroid biosynthesis_Homo sapiens_hsa001001.13834675
35Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.11992290
36Selenocompound metabolism_Homo sapiens_hsa004501.07164137
37Epstein-Barr virus infection_Homo sapiens_hsa051690.97395272
38Folate biosynthesis_Homo sapiens_hsa007900.95871434
39Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.93431835
40Systemic lupus erythematosus_Homo sapiens_hsa053220.91066812
41Thyroid cancer_Homo sapiens_hsa052160.88410572
42Viral carcinogenesis_Homo sapiens_hsa052030.83948637
43Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.83795315
44Biosynthesis of amino acids_Homo sapiens_hsa012300.83186149
45Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.82672515
46HTLV-I infection_Homo sapiens_hsa051660.82460335
47Maturity onset diabetes of the young_Homo sapiens_hsa049500.79976964
48Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.79158547
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.76921126
50Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.76337910
51Phototransduction_Homo sapiens_hsa047440.75668281
52Cyanoamino acid metabolism_Homo sapiens_hsa004600.74667639
53Alcoholism_Homo sapiens_hsa050340.74200588
54Peroxisome_Homo sapiens_hsa041460.72834172
55Basal cell carcinoma_Homo sapiens_hsa052170.71220680
56Nitrogen metabolism_Homo sapiens_hsa009100.70465585
57Hippo signaling pathway_Homo sapiens_hsa043900.70332307
58MicroRNAs in cancer_Homo sapiens_hsa052060.70015931
59Notch signaling pathway_Homo sapiens_hsa043300.69521144
60Vitamin digestion and absorption_Homo sapiens_hsa049770.68449639
61Protein export_Homo sapiens_hsa030600.67861085
62Alzheimers disease_Homo sapiens_hsa050100.66601425
63Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.66380517
64Cysteine and methionine metabolism_Homo sapiens_hsa002700.66215584
65Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.66035665
66Colorectal cancer_Homo sapiens_hsa052100.65690450
67N-Glycan biosynthesis_Homo sapiens_hsa005100.61743362
68Drug metabolism - other enzymes_Homo sapiens_hsa009830.59625572
69Fatty acid metabolism_Homo sapiens_hsa012120.59210594
70Herpes simplex infection_Homo sapiens_hsa051680.57623714
71Tryptophan metabolism_Homo sapiens_hsa003800.56355952
72Sulfur metabolism_Homo sapiens_hsa009200.54586660
73Hedgehog signaling pathway_Homo sapiens_hsa043400.53695142
74Central carbon metabolism in cancer_Homo sapiens_hsa052300.53542198
75Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49263587
76Lysine degradation_Homo sapiens_hsa003100.48047890
77Bladder cancer_Homo sapiens_hsa052190.47865346
78Pentose phosphate pathway_Homo sapiens_hsa000300.47324534
79Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.47021936
80Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.45304070
81alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.42785116
82Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42501334
83Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.42124132
84TGF-beta signaling pathway_Homo sapiens_hsa043500.42030485
85Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41439217
86Linoleic acid metabolism_Homo sapiens_hsa005910.40834946
87Carbon metabolism_Homo sapiens_hsa012000.40290648
88Caffeine metabolism_Homo sapiens_hsa002320.39730616
89mTOR signaling pathway_Homo sapiens_hsa041500.38232644
90Fructose and mannose metabolism_Homo sapiens_hsa000510.38075454
91Regulation of autophagy_Homo sapiens_hsa041400.37807065
92Wnt signaling pathway_Homo sapiens_hsa043100.37115437
93Primary bile acid biosynthesis_Homo sapiens_hsa001200.36299687
94Small cell lung cancer_Homo sapiens_hsa052220.35496032
95Primary immunodeficiency_Homo sapiens_hsa053400.35072224
96Olfactory transduction_Homo sapiens_hsa047400.34239626
97Antigen processing and presentation_Homo sapiens_hsa046120.32988628
982-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.32013041
99Prostate cancer_Homo sapiens_hsa052150.31182827
100Thyroid hormone signaling pathway_Homo sapiens_hsa049190.30799105
101Pathways in cancer_Homo sapiens_hsa052000.28846530
102Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.28830218
103Chronic myeloid leukemia_Homo sapiens_hsa052200.28741667
104Fatty acid degradation_Homo sapiens_hsa000710.28315390
105Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.27873735
106beta-Alanine metabolism_Homo sapiens_hsa004100.27196984
107Tight junction_Homo sapiens_hsa045300.26346043
108Non-small cell lung cancer_Homo sapiens_hsa052230.24144905
109Melanoma_Homo sapiens_hsa052180.22292227
110Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.20906927
111Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.20886488
112SNARE interactions in vesicular transport_Homo sapiens_hsa041300.19683765
113Galactose metabolism_Homo sapiens_hsa000520.19058067
114Arginine and proline metabolism_Homo sapiens_hsa003300.18665207
115Glutathione metabolism_Homo sapiens_hsa004800.18519389
116Vitamin B6 metabolism_Homo sapiens_hsa007500.18218538
117Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.18018370
118Gap junction_Homo sapiens_hsa045400.17910554
119Adherens junction_Homo sapiens_hsa045200.17521106
120Steroid hormone biosynthesis_Homo sapiens_hsa001400.16260881
121Hepatitis B_Homo sapiens_hsa051610.15511171
122Huntingtons disease_Homo sapiens_hsa050160.14959427
123Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.14355910
124HIF-1 signaling pathway_Homo sapiens_hsa040660.14355632
125Retinol metabolism_Homo sapiens_hsa008300.13649061
126Ether lipid metabolism_Homo sapiens_hsa005650.13340212
127Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.13219194
128Fat digestion and absorption_Homo sapiens_hsa049750.12275557
129Glucagon signaling pathway_Homo sapiens_hsa049220.11413565
130Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.09812284
131Acute myeloid leukemia_Homo sapiens_hsa052210.09627586
132Long-term potentiation_Homo sapiens_hsa047200.08987923
133Apoptosis_Homo sapiens_hsa042100.08385440
134Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.08238182
135Endometrial cancer_Homo sapiens_hsa052130.08172556
136Pyruvate metabolism_Homo sapiens_hsa006200.07727247
137Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.07571607
138Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.07251293
139Metabolic pathways_Homo sapiens_hsa011000.06511980
140Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.06227840
141Neurotrophin signaling pathway_Homo sapiens_hsa047220.04502889
142Glioma_Homo sapiens_hsa052140.04381481
143AMPK signaling pathway_Homo sapiens_hsa041520.04169827

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