

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | DNA deamination (GO:0045006) | 6.32884061 |
| 2 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 5.93926781 |
| 3 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 5.71516153 |
| 4 | cytidine metabolic process (GO:0046087) | 5.68274238 |
| 5 | cytidine catabolic process (GO:0006216) | 5.68274238 |
| 6 | cytidine deamination (GO:0009972) | 5.68274238 |
| 7 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 5.51933368 |
| 8 | actin nucleation (GO:0045010) | 5.25937594 |
| 9 | sequestering of actin monomers (GO:0042989) | 5.01422263 |
| 10 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.80235909 |
| 11 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 4.63709668 |
| 12 | ATP synthesis coupled proton transport (GO:0015986) | 4.63709668 |
| 13 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.55366647 |
| 14 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.49891291 |
| 15 | proteasome assembly (GO:0043248) | 4.49556662 |
| 16 | regulation of T cell tolerance induction (GO:0002664) | 4.37634370 |
| 17 | regulation of cellular amino acid metabolic process (GO:0006521) | 4.25635848 |
| 18 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 4.14858549 |
| 19 | respiratory electron transport chain (GO:0022904) | 4.13570562 |
| 20 | platelet dense granule organization (GO:0060155) | 4.13035061 |
| 21 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 4.07441360 |
| 22 | electron transport chain (GO:0022900) | 4.03089160 |
| 23 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.97749241 |
| 24 | regulation of tolerance induction (GO:0002643) | 3.88654883 |
| 25 | positive regulation of tolerance induction (GO:0002645) | 3.87007352 |
| 26 | positive regulation of interleukin-8 secretion (GO:2000484) | 3.84107330 |
| 27 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.80413547 |
| 28 | immunoglobulin mediated immune response (GO:0016064) | 3.72583001 |
| 29 | regulation of interleukin-8 secretion (GO:2000482) | 3.71433658 |
| 30 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.69552166 |
| 31 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.67915747 |
| 32 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.67915747 |
| 33 | cytolysis (GO:0019835) | 3.67513043 |
| 34 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.63453593 |
| 35 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.63453593 |
| 36 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.63453593 |
| 37 | positive thymic T cell selection (GO:0045059) | 3.62499800 |
| 38 | positive regulation of interleukin-2 biosynthetic process (GO:0045086) | 3.61238362 |
| 39 | positive T cell selection (GO:0043368) | 3.59920720 |
| 40 | negative regulation of ligase activity (GO:0051352) | 3.53720296 |
| 41 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.53720296 |
| 42 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.46010474 |
| 43 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.46010474 |
| 44 | T cell costimulation (GO:0031295) | 3.44099297 |
| 45 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.43831609 |
| 46 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.42144064 |
| 47 | T cell migration (GO:0072678) | 3.40661998 |
| 48 | lymphocyte costimulation (GO:0031294) | 3.40299022 |
| 49 | respiratory chain complex IV assembly (GO:0008535) | 3.35463057 |
| 50 | protein neddylation (GO:0045116) | 3.33069966 |
| 51 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 3.30856489 |
| 52 | positive regulation of lamellipodium assembly (GO:0010592) | 3.29417155 |
| 53 | B cell mediated immunity (GO:0019724) | 3.27409404 |
| 54 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 3.25470640 |
| 55 | deoxyribonucleoside triphosphate metabolic process (GO:0009200) | 3.22161673 |
| 56 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.19944686 |
| 57 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.19103094 |
| 58 | T cell receptor signaling pathway (GO:0050852) | 3.18796075 |
| 59 | GPI anchor biosynthetic process (GO:0006506) | 3.15142865 |
| 60 | positive regulation of calcium-mediated signaling (GO:0050850) | 3.14584279 |
| 61 | purine deoxyribonucleotide catabolic process (GO:0009155) | 3.12524548 |
| 62 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.12388599 |
| 63 | positive regulation of interleukin-4 production (GO:0032753) | 3.10385415 |
| 64 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.08303762 |
| 65 | positive regulation of monocyte chemotaxis (GO:0090026) | 3.06631405 |
| 66 | negative regulation of T cell apoptotic process (GO:0070233) | 3.06464408 |
| 67 | regulation of cellular amine metabolic process (GO:0033238) | 3.05839568 |
| 68 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.03796408 |
| 69 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 3.02906339 |
| 70 | cellular response to interleukin-15 (GO:0071350) | 3.02302010 |
| 71 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 3.02118021 |
| 72 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.99620972 |
| 73 | negative T cell selection (GO:0043383) | 2.99503412 |
| 74 | mast cell activation (GO:0045576) | 2.98956445 |
| 75 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.95102809 |
| 76 | positive regulation of ligase activity (GO:0051351) | 2.93418165 |
| 77 | GPI anchor metabolic process (GO:0006505) | 2.87707825 |
| 78 | response to interferon-beta (GO:0035456) | 2.85937106 |
| 79 | pyrimidine nucleoside catabolic process (GO:0046135) | 2.85438779 |
| 80 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 2.84904579 |
| 81 | negative regulation of stress fiber assembly (GO:0051497) | 2.84857333 |
| 82 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.84166595 |
| 83 | production of molecular mediator involved in inflammatory response (GO:0002532) | 2.83774247 |
| 84 | cytochrome complex assembly (GO:0017004) | 2.83608536 |
| 85 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 2.82795223 |
| 86 | termination of RNA polymerase III transcription (GO:0006386) | 2.82795223 |
| 87 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.82271752 |
| 88 | positive regulation of cell cycle arrest (GO:0071158) | 2.80238541 |
| 89 | regulation of regulatory T cell differentiation (GO:0045589) | 2.80051697 |
| 90 | regulation of interleukin-2 biosynthetic process (GO:0045076) | 2.75940435 |
| 91 | hydrogen ion transmembrane transport (GO:1902600) | 2.74504377 |
| 92 | cell wall macromolecule metabolic process (GO:0044036) | 2.72986504 |
| 93 | deoxyribonucleotide catabolic process (GO:0009264) | 2.70104351 |
| 94 | regulation of leukocyte mediated cytotoxicity (GO:0001910) | 2.67808783 |
| 95 | ribosomal small subunit assembly (GO:0000028) | 2.66883243 |
| 96 | antigen receptor-mediated signaling pathway (GO:0050851) | 2.65428877 |
| 97 | regulation of cellular respiration (GO:0043457) | 2.65095972 |
| 98 | positive regulation of cell killing (GO:0031343) | 2.63478847 |
| 99 | positive regulation of inflammatory response to antigenic stimulus (GO:0002863) | 2.63387714 |
| 100 | positive regulation of lamellipodium organization (GO:1902745) | 2.62805092 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 5.98542529 |
| 2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.70791048 |
| 3 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 3.88959852 |
| 4 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.52107799 |
| 5 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.29506725 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.99439136 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.99272587 |
| 8 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.93510212 |
| 9 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.93156137 |
| 10 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.83444193 |
| 11 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.77027375 |
| 12 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.75709354 |
| 13 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.73451433 |
| 14 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 2.61867922 |
| 15 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 2.53922787 |
| 16 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.50918390 |
| 17 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 2.41694416 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.16695309 |
| 19 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.11585612 |
| 20 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 2.06594552 |
| 21 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.99570972 |
| 22 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.97457366 |
| 23 | MYB_26560356_Chip-Seq_TH2_Human | 1.95167506 |
| 24 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.75481279 |
| 25 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.69330648 |
| 26 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.69189045 |
| 27 | GATA3_26560356_Chip-Seq_TH2_Human | 1.66944511 |
| 28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.65647853 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.62306524 |
| 30 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.58821020 |
| 31 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.53411233 |
| 32 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.50982012 |
| 33 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.50047000 |
| 34 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.48399620 |
| 35 | EWS_26573619_Chip-Seq_HEK293_Human | 1.46842927 |
| 36 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.41980810 |
| 37 | AR_20517297_ChIP-Seq_VCAP_Human | 1.39021969 |
| 38 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.35768287 |
| 39 | PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 1.34136864 |
| 40 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.32665066 |
| 41 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.31798022 |
| 42 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.31074694 |
| 43 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.30335354 |
| 44 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.28072908 |
| 45 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.25915470 |
| 46 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.25915470 |
| 47 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.25667533 |
| 48 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.25533272 |
| 49 | RUNX_20019798_ChIP-Seq_JUKART_Human | 1.25067722 |
| 50 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.24549476 |
| 51 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.24031176 |
| 52 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.23493896 |
| 53 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.22441078 |
| 54 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.20775580 |
| 55 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.20775580 |
| 56 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.19744023 |
| 57 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.17933537 |
| 58 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.15615321 |
| 59 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.15615321 |
| 60 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.14798072 |
| 61 | ERG_20517297_ChIP-Seq_VCAP_Human | 1.14466296 |
| 62 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.13444561 |
| 63 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 1.13434172 |
| 64 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.13432942 |
| 65 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.11399797 |
| 66 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.10783027 |
| 67 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.10534834 |
| 68 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.08716320 |
| 69 | MYB_26560356_Chip-Seq_TH1_Human | 1.07835696 |
| 70 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.07141874 |
| 71 | NCOR_22424771_ChIP-Seq_293T_Human | 1.06998922 |
| 72 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 1.06937955 |
| 73 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 1.04061926 |
| 74 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 1.03210390 |
| 75 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.02163832 |
| 76 | GATA3_26560356_Chip-Seq_TH1_Human | 1.01840011 |
| 77 | TAF2_19829295_ChIP-Seq_ESCs_Human | 1.01044913 |
| 78 | P300_19829295_ChIP-Seq_ESCs_Human | 1.00725634 |
| 79 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.00115188 |
| 80 | MYC_19829295_ChIP-Seq_ESCs_Human | 0.99730697 |
| 81 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.98868341 |
| 82 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.98690414 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.97078763 |
| 84 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96712827 |
| 85 | GATA6_21074721_ChIP-Seq_CACO-2_Mouse | 0.95822721 |
| 86 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.93483139 |
| 87 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 0.93437505 |
| 88 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.93234948 |
| 89 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.93044584 |
| 90 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.92645328 |
| 91 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.92217037 |
| 92 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.91669569 |
| 93 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90782110 |
| 94 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 0.90698465 |
| 95 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.89639177 |
| 96 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.89458800 |
| 97 | FUS_26573619_Chip-Seq_HEK293_Human | 0.88309817 |
| 98 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.86871955 |
| 99 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.86337050 |
| 100 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 0.86145520 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0005671_abnormal_response_to | 6.01672584 |
| 2 | MP0001835_abnormal_antigen_presentation | 4.51982578 |
| 3 | MP0002166_altered_tumor_susceptibility | 3.59585501 |
| 4 | MP0009785_altered_susceptibility_to | 3.22333195 |
| 5 | MP0009333_abnormal_splenocyte_physiolog | 3.17483316 |
| 6 | MP0002006_tumorigenesis | 2.87205579 |
| 7 | MP0005000_abnormal_immune_tolerance | 2.62578325 |
| 8 | MP0003806_abnormal_nucleotide_metabolis | 2.61005958 |
| 9 | MP0006072_abnormal_retinal_apoptosis | 2.32057523 |
| 10 | MP0001800_abnormal_humoral_immune | 2.21164686 |
| 11 | MP0002102_abnormal_ear_morphology | 2.15361479 |
| 12 | MP0005025_abnormal_response_to | 2.08333415 |
| 13 | MP0002723_abnormal_immune_serum | 2.04681626 |
| 14 | MP0003763_abnormal_thymus_physiology | 2.03903170 |
| 15 | MP0002420_abnormal_adaptive_immunity | 2.02911622 |
| 16 | MP0001819_abnormal_immune_cell | 1.99084642 |
| 17 | MP0009764_decreased_sensitivity_to | 1.98424227 |
| 18 | MP0003866_abnormal_defecation | 1.94808235 |
| 19 | MP0006082_CNS_inflammation | 1.91926036 |
| 20 | MP0003195_calcinosis | 1.91494800 |
| 21 | MP0008872_abnormal_physiological_respon | 1.86375680 |
| 22 | MP0002452_abnormal_antigen_presenting | 1.85244095 |
| 23 | MP0005646_abnormal_pituitary_gland | 1.82520927 |
| 24 | MP0002148_abnormal_hypersensitivity_rea | 1.77840109 |
| 25 | MP0001905_abnormal_dopamine_level | 1.75545970 |
| 26 | MP0001919_abnormal_reproductive_system | 1.69594594 |
| 27 | MP0010155_abnormal_intestine_physiology | 1.64236761 |
| 28 | MP0003724_increased_susceptibility_to | 1.58471753 |
| 29 | MP0009379_abnormal_foot_pigmentation | 1.56233453 |
| 30 | MP0003787_abnormal_imprinting | 1.53370438 |
| 31 | MP0001845_abnormal_inflammatory_respons | 1.49518888 |
| 32 | MP0000716_abnormal_immune_system | 1.44866231 |
| 33 | MP0005387_immune_system_phenotype | 1.41255595 |
| 34 | MP0001790_abnormal_immune_system | 1.41255595 |
| 35 | MP0001529_abnormal_vocalization | 1.40941466 |
| 36 | MP0002419_abnormal_innate_immunity | 1.39879362 |
| 37 | MP0005464_abnormal_platelet_physiology | 1.36908135 |
| 38 | MP0005645_abnormal_hypothalamus_physiol | 1.32668347 |
| 39 | MP0003646_muscle_fatigue | 1.32397724 |
| 40 | MP0002398_abnormal_bone_marrow | 1.31851057 |
| 41 | MP0005253_abnormal_eye_physiology | 1.31844042 |
| 42 | MP0000372_irregular_coat_pigmentation | 1.29856007 |
| 43 | MP0000685_abnormal_immune_system | 1.28911216 |
| 44 | MP0005389_reproductive_system_phenotype | 1.26500168 |
| 45 | MP0001765_abnormal_ion_homeostasis | 1.26078751 |
| 46 | MP0003436_decreased_susceptibility_to | 1.25248523 |
| 47 | MP0005551_abnormal_eye_electrophysiolog | 1.22696054 |
| 48 | MP0004147_increased_porphyrin_level | 1.21832733 |
| 49 | MP0001873_stomach_inflammation | 1.21296655 |
| 50 | MP0008877_abnormal_DNA_methylation | 1.20373815 |
| 51 | MP0009697_abnormal_copulation | 1.19468913 |
| 52 | MP0008995_early_reproductive_senescence | 1.17857695 |
| 53 | MP0006036_abnormal_mitochondrial_physio | 1.16675712 |
| 54 | MP0004145_abnormal_muscle_electrophysio | 1.16657002 |
| 55 | MP0003448_altered_tumor_morphology | 1.13132789 |
| 56 | MP0003880_abnormal_central_pattern | 1.12484628 |
| 57 | MP0005636_abnormal_mineral_homeostasis | 1.09800678 |
| 58 | MP0009763_increased_sensitivity_to | 1.08177046 |
| 59 | MP0002837_dystrophic_cardiac_calcinosis | 1.07943644 |
| 60 | MP0002405_respiratory_system_inflammati | 1.07525261 |
| 61 | MP0005367_renal/urinary_system_phenotyp | 1.05787696 |
| 62 | MP0000516_abnormal_urinary_system | 1.05787696 |
| 63 | MP0001764_abnormal_homeostasis | 1.05656521 |
| 64 | MP0008875_abnormal_xenobiotic_pharmacok | 1.05492146 |
| 65 | MP0008469_abnormal_protein_level | 1.04972146 |
| 66 | MP0002429_abnormal_blood_cell | 1.04816369 |
| 67 | MP0000689_abnormal_spleen_morphology | 1.04147056 |
| 68 | MP0005166_decreased_susceptibility_to | 1.01735785 |
| 69 | MP0005075_abnormal_melanosome_morpholog | 0.99756133 |
| 70 | MP0002138_abnormal_hepatobiliary_system | 0.99624554 |
| 71 | MP0002722_abnormal_immune_system | 0.99275684 |
| 72 | MP0002163_abnormal_gland_morphology | 0.97390641 |
| 73 | MP0002822_catalepsy | 0.89792779 |
| 74 | MP0000639_abnormal_adrenal_gland | 0.88016164 |
| 75 | MP0002933_joint_inflammation | 0.86408245 |
| 76 | MP0003786_premature_aging | 0.84823873 |
| 77 | MP0002277_abnormal_respiratory_mucosa | 0.84695351 |
| 78 | MP0000858_altered_metastatic_potential | 0.83830976 |
| 79 | MP0000703_abnormal_thymus_morphology | 0.83043768 |
| 80 | MP0005084_abnormal_gallbladder_morpholo | 0.80913197 |
| 81 | MP0001968_abnormal_touch/_nociception | 0.75899477 |
| 82 | MP0001661_extended_life_span | 0.75836278 |
| 83 | MP0002095_abnormal_skin_pigmentation | 0.73510122 |
| 84 | MP0004947_skin_inflammation | 0.73366731 |
| 85 | MP0003638_abnormal_response/metabolism_ | 0.73069092 |
| 86 | MP0003075_altered_response_to | 0.73056835 |
| 87 | MP0010386_abnormal_urinary_bladder | 0.72969391 |
| 88 | MP0005085_abnormal_gallbladder_physiolo | 0.72708636 |
| 89 | MP0006276_abnormal_autonomic_nervous | 0.68906376 |
| 90 | MP0001485_abnormal_pinna_reflex | 0.68815021 |
| 91 | MP0001970_abnormal_pain_threshold | 0.68124600 |
| 92 | MP0009745_abnormal_behavioral_response | 0.65704986 |
| 93 | MP0001119_abnormal_female_reproductive | 0.64329667 |
| 94 | MP0003252_abnormal_bile_duct | 0.63036464 |
| 95 | MP0002019_abnormal_tumor_incidence | 0.62898881 |
| 96 | MP0002693_abnormal_pancreas_physiology | 0.62143981 |
| 97 | MP0002272_abnormal_nervous_system | 0.59051977 |
| 98 | MP0003137_abnormal_impulse_conducting | 0.58104107 |
| 99 | MP0001486_abnormal_startle_reflex | 0.57615721 |
| 100 | MP0009046_muscle_twitch | 0.57348157 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Mitochondrial inheritance (HP:0001427) | 4.66715440 |
| 2 | Acute necrotizing encephalopathy (HP:0006965) | 4.45658848 |
| 3 | Aplastic anemia (HP:0001915) | 4.32353331 |
| 4 | Hepatocellular necrosis (HP:0001404) | 4.30525494 |
| 5 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.01051594 |
| 6 | Progressive macrocephaly (HP:0004481) | 3.87238673 |
| 7 | Increased CSF lactate (HP:0002490) | 3.81132727 |
| 8 | Hepatic necrosis (HP:0002605) | 3.80907199 |
| 9 | T lymphocytopenia (HP:0005403) | 3.79610925 |
| 10 | Hypoproteinemia (HP:0003075) | 3.74021819 |
| 11 | Severe combined immunodeficiency (HP:0004430) | 3.66416993 |
| 12 | Acute encephalopathy (HP:0006846) | 3.58280442 |
| 13 | Abnormality of T cell number (HP:0011839) | 3.54261282 |
| 14 | Elevated erythrocyte sedimentation rate (HP:0003565) | 3.46500574 |
| 15 | Increased hepatocellular lipid droplets (HP:0006565) | 3.24590887 |
| 16 | IgG deficiency (HP:0004315) | 3.22758074 |
| 17 | Congenital, generalized hypertrichosis (HP:0004540) | 3.20911173 |
| 18 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.15278897 |
| 19 | Cerebral edema (HP:0002181) | 3.14498004 |
| 20 | Type I transferrin isoform profile (HP:0003642) | 3.05019774 |
| 21 | Abnormality of the prostate (HP:0008775) | 3.01921723 |
| 22 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.00054260 |
| 23 | Thyroiditis (HP:0100646) | 2.99319393 |
| 24 | Lipid accumulation in hepatocytes (HP:0006561) | 2.90439529 |
| 25 | Increased intramyocellular lipid droplets (HP:0012240) | 2.86251610 |
| 26 | Hypothermia (HP:0002045) | 2.83019959 |
| 27 | Renal Fanconi syndrome (HP:0001994) | 2.81933301 |
| 28 | Combined immunodeficiency (HP:0005387) | 2.74269568 |
| 29 | Abnormality of eosinophils (HP:0001879) | 2.73983326 |
| 30 | Attenuation of retinal blood vessels (HP:0007843) | 2.73553997 |
| 31 | Abolished electroretinogram (ERG) (HP:0000550) | 2.73255097 |
| 32 | Exertional dyspnea (HP:0002875) | 2.72926799 |
| 33 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.66321394 |
| 34 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.66321394 |
| 35 | B lymphocytopenia (HP:0010976) | 2.60153451 |
| 36 | Severe visual impairment (HP:0001141) | 2.55983527 |
| 37 | Abnormality of B cell number (HP:0010975) | 2.55548823 |
| 38 | Decreased central vision (HP:0007663) | 2.51807428 |
| 39 | Pancreatic cysts (HP:0001737) | 2.50579671 |
| 40 | Tetany (HP:0001281) | 2.48897588 |
| 41 | Eosinophilia (HP:0001880) | 2.46981199 |
| 42 | Lactic acidosis (HP:0003128) | 2.43396785 |
| 43 | Increased serum lactate (HP:0002151) | 2.41701840 |
| 44 | Optic disc pallor (HP:0000543) | 2.38170063 |
| 45 | Increased muscle lipid content (HP:0009058) | 2.37208228 |
| 46 | Autoimmune hemolytic anemia (HP:0001890) | 2.36646137 |
| 47 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.35364525 |
| 48 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.35364525 |
| 49 | Abnormal protein glycosylation (HP:0012346) | 2.35364525 |
| 50 | Abnormal glycosylation (HP:0012345) | 2.35364525 |
| 51 | Abnormal albumin level (HP:0012116) | 2.34391677 |
| 52 | Hypoalbuminemia (HP:0003073) | 2.34391677 |
| 53 | Generalized aminoaciduria (HP:0002909) | 2.33942852 |
| 54 | Alveolar cell carcinoma (HP:0006519) | 2.33347854 |
| 55 | Congenital stationary night blindness (HP:0007642) | 2.33289431 |
| 56 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.33192869 |
| 57 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.28473058 |
| 58 | Microretrognathia (HP:0000308) | 2.22372129 |
| 59 | Abnormality of T cells (HP:0002843) | 2.18310886 |
| 60 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.16620045 |
| 61 | Leukocytosis (HP:0001974) | 2.15372831 |
| 62 | Chronic diarrhea (HP:0002028) | 2.12474825 |
| 63 | Leukodystrophy (HP:0002415) | 2.12330217 |
| 64 | Increased IgM level (HP:0003496) | 2.11323726 |
| 65 | Neoplasm of the tracheobronchial system (HP:0100552) | 2.07633366 |
| 66 | Respiratory failure (HP:0002878) | 2.05974411 |
| 67 | True hermaphroditism (HP:0010459) | 2.03256347 |
| 68 | Exercise intolerance (HP:0003546) | 1.97401831 |
| 69 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 1.93502959 |
| 70 | Radial bowing (HP:0002986) | 1.93201839 |
| 71 | Hypomagnesemia (HP:0002917) | 1.93009419 |
| 72 | 3-Methylglutaconic aciduria (HP:0003535) | 1.91907010 |
| 73 | Split foot (HP:0001839) | 1.90257458 |
| 74 | Reduced antithrombin III activity (HP:0001976) | 1.89281257 |
| 75 | Pustule (HP:0200039) | 1.88989965 |
| 76 | Short tibia (HP:0005736) | 1.88012726 |
| 77 | Encephalitis (HP:0002383) | 1.87161631 |
| 78 | Granulocytopenia (HP:0001913) | 1.86984414 |
| 79 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.85710483 |
| 80 | Abnormality of alanine metabolism (HP:0010916) | 1.85710483 |
| 81 | Hyperalaninemia (HP:0003348) | 1.85710483 |
| 82 | Conjunctival hamartoma (HP:0100780) | 1.84184410 |
| 83 | Abnormality of the middle phalanx of the 5th finger (HP:0004219) | 1.83186164 |
| 84 | Abnormality of the axillary hair (HP:0100134) | 1.83046685 |
| 85 | Abnormality of secondary sexual hair (HP:0009888) | 1.83046685 |
| 86 | Keratoconjunctivitis (HP:0001096) | 1.82954668 |
| 87 | Lethargy (HP:0001254) | 1.81010760 |
| 88 | Myositis (HP:0100614) | 1.79967277 |
| 89 | Respiratory difficulties (HP:0002880) | 1.78061865 |
| 90 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.76036007 |
| 91 | Stomatitis (HP:0010280) | 1.73529014 |
| 92 | Recurrent abscess formation (HP:0002722) | 1.72363812 |
| 93 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.71693366 |
| 94 | Pancreatic fibrosis (HP:0100732) | 1.71338033 |
| 95 | Abnormal drinking behavior (HP:0030082) | 1.71129234 |
| 96 | Polydipsia (HP:0001959) | 1.71129234 |
| 97 | Abnormality of midbrain morphology (HP:0002418) | 1.71083189 |
| 98 | Molar tooth sign on MRI (HP:0002419) | 1.71083189 |
| 99 | Cerebral palsy (HP:0100021) | 1.69967309 |
| 100 | Abnormality of magnesium homeostasis (HP:0004921) | 1.69177119 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDR | 5.20686884 |
| 2 | TESK2 | 4.36127400 |
| 3 | BCKDK | 4.26521742 |
| 4 | MAP3K12 | 4.17448186 |
| 5 | TESK1 | 2.55791605 |
| 6 | TXK | 2.40428797 |
| 7 | TAOK3 | 2.38124613 |
| 8 | MYLK | 2.36307877 |
| 9 | BMPR2 | 2.25061332 |
| 10 | TLK1 | 2.12197520 |
| 11 | MAP4K1 | 2.10145450 |
| 12 | LIMK1 | 2.07348142 |
| 13 | GRK6 | 2.04115496 |
| 14 | MST4 | 1.88714287 |
| 15 | ERBB3 | 1.70486697 |
| 16 | STK16 | 1.69046263 |
| 17 | VRK2 | 1.66527515 |
| 18 | ZAK | 1.64759778 |
| 19 | TEC | 1.64280916 |
| 20 | ITK | 1.63202932 |
| 21 | CDK19 | 1.58774302 |
| 22 | NUAK1 | 1.54591046 |
| 23 | RPS6KA4 | 1.48114159 |
| 24 | CSF1R | 1.39951629 |
| 25 | VRK1 | 1.38518705 |
| 26 | MAP4K2 | 1.37278327 |
| 27 | RIPK4 | 1.32037729 |
| 28 | PIK3CG | 1.27285322 |
| 29 | SYK | 1.25299112 |
| 30 | ADRBK2 | 1.24237578 |
| 31 | DAPK1 | 1.23710445 |
| 32 | BTK | 1.23148144 |
| 33 | CSNK1G3 | 1.14375997 |
| 34 | BUB1 | 1.11675564 |
| 35 | TNK2 | 1.10010142 |
| 36 | ILK | 1.05709166 |
| 37 | GRK1 | 1.05033338 |
| 38 | LCK | 0.98931572 |
| 39 | CSNK1G2 | 0.98049982 |
| 40 | TRPM7 | 0.98019277 |
| 41 | EIF2AK3 | 0.97271776 |
| 42 | LYN | 0.97215836 |
| 43 | FRK | 0.94946058 |
| 44 | CSNK1A1L | 0.93397345 |
| 45 | TIE1 | 0.93313725 |
| 46 | RPS6KA5 | 0.93240330 |
| 47 | PRKCQ | 0.89459116 |
| 48 | INSRR | 0.89234628 |
| 49 | KIT | 0.85399287 |
| 50 | BCR | 0.85075337 |
| 51 | DAPK3 | 0.83032963 |
| 52 | CSNK1G1 | 0.80410019 |
| 53 | GRK7 | 0.77249572 |
| 54 | SCYL2 | 0.76635698 |
| 55 | TRIM28 | 0.76613268 |
| 56 | ZAP70 | 0.74271434 |
| 57 | IKBKE | 0.73879222 |
| 58 | IKBKB | 0.73218509 |
| 59 | WNK3 | 0.73168060 |
| 60 | PRKCE | 0.69515966 |
| 61 | OBSCN | 0.67388470 |
| 62 | ROCK1 | 0.66041386 |
| 63 | FES | 0.65676585 |
| 64 | MUSK | 0.62558754 |
| 65 | MAPK13 | 0.61457771 |
| 66 | CAMKK2 | 0.57026250 |
| 67 | IGF1R | 0.56350131 |
| 68 | CLK1 | 0.56082963 |
| 69 | DYRK2 | 0.55696990 |
| 70 | PKN1 | 0.53307415 |
| 71 | PRKG2 | 0.50805265 |
| 72 | EGFR | 0.50793233 |
| 73 | JAK3 | 0.50661715 |
| 74 | OXSR1 | 0.50357630 |
| 75 | CSK | 0.49515937 |
| 76 | NME2 | 0.47745184 |
| 77 | ABL1 | 0.42523989 |
| 78 | HCK | 0.41878150 |
| 79 | ADRBK1 | 0.41027292 |
| 80 | PAK1 | 0.40836686 |
| 81 | PIM1 | 0.40590256 |
| 82 | PAK4 | 0.38303294 |
| 83 | PRKACA | 0.38133333 |
| 84 | PRKCA | 0.37197575 |
| 85 | PIK3CA | 0.36827822 |
| 86 | TBK1 | 0.36178040 |
| 87 | INSR | 0.32311692 |
| 88 | FLT3 | 0.31938239 |
| 89 | PLK4 | 0.30599494 |
| 90 | CDK8 | 0.29984634 |
| 91 | FYN | 0.29791309 |
| 92 | PRKG1 | 0.28709534 |
| 93 | CSNK2A1 | 0.27975657 |
| 94 | CAMK2G | 0.27622134 |
| 95 | ABL2 | 0.27355839 |
| 96 | SRPK1 | 0.27323033 |
| 97 | AURKB | 0.27199993 |
| 98 | MAP2K7 | 0.26113557 |
| 99 | CSNK2A2 | 0.25934052 |
| 100 | SIK3 | 0.25207875 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.72585334 |
| 2 | Graft-versus-host disease_Homo sapiens_hsa05332 | 4.04281556 |
| 3 | Allograft rejection_Homo sapiens_hsa05330 | 3.85359945 |
| 4 | Asthma_Homo sapiens_hsa05310 | 3.77690726 |
| 5 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 3.74774906 |
| 6 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.49524606 |
| 7 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 3.30330199 |
| 8 | Primary immunodeficiency_Homo sapiens_hsa05340 | 3.01872968 |
| 9 | Antigen processing and presentation_Homo sapiens_hsa04612 | 2.86857901 |
| 10 | Parkinsons disease_Homo sapiens_hsa05012 | 2.83705240 |
| 11 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 2.64227201 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.47262666 |
| 13 | RNA polymerase_Homo sapiens_hsa03020 | 2.23318057 |
| 14 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 2.04297219 |
| 15 | Viral myocarditis_Homo sapiens_hsa05416 | 2.00127306 |
| 16 | Alzheimers disease_Homo sapiens_hsa05010 | 1.92410380 |
| 17 | Ribosome_Homo sapiens_hsa03010 | 1.92032669 |
| 18 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.87335573 |
| 19 | Huntingtons disease_Homo sapiens_hsa05016 | 1.76915093 |
| 20 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.71965621 |
| 21 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.69572738 |
| 22 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.67367402 |
| 23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.53822470 |
| 24 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.43264910 |
| 25 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.42016572 |
| 26 | Phototransduction_Homo sapiens_hsa04744 | 1.41203328 |
| 27 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 1.29449446 |
| 28 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.16956095 |
| 29 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 1.14491430 |
| 30 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 1.10770205 |
| 31 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 1.01537316 |
| 32 | Leishmaniasis_Homo sapiens_hsa05140 | 0.96964672 |
| 33 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 0.93914134 |
| 34 | Salmonella infection_Homo sapiens_hsa05132 | 0.75523485 |
| 35 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.74587600 |
| 36 | Shigellosis_Homo sapiens_hsa05131 | 0.74085634 |
| 37 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.71106191 |
| 38 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.70033798 |
| 39 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.69295934 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 0.69147589 |
| 41 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.68063571 |
| 42 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.67226869 |
| 43 | Measles_Homo sapiens_hsa05162 | 0.65905434 |
| 44 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.63603469 |
| 45 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63069830 |
| 46 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.62716538 |
| 47 | Homologous recombination_Homo sapiens_hsa03440 | 0.61898311 |
| 48 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.61848575 |
| 49 | Purine metabolism_Homo sapiens_hsa00230 | 0.61694436 |
| 50 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.60777142 |
| 51 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.60434273 |
| 52 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.60123539 |
| 53 | Spliceosome_Homo sapiens_hsa03040 | 0.56324448 |
| 54 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56038988 |
| 55 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.54568062 |
| 56 | Peroxisome_Homo sapiens_hsa04146 | 0.51907284 |
| 57 | Phagosome_Homo sapiens_hsa04145 | 0.51409492 |
| 58 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.51384460 |
| 59 | Tuberculosis_Homo sapiens_hsa05152 | 0.50455500 |
| 60 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.50141414 |
| 61 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.50135654 |
| 62 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.48487374 |
| 63 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.48175698 |
| 64 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.46565017 |
| 65 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.46412767 |
| 66 | DNA replication_Homo sapiens_hsa03030 | 0.46125628 |
| 67 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.44680063 |
| 68 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.44348204 |
| 69 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.43240342 |
| 70 | Pertussis_Homo sapiens_hsa05133 | 0.42662001 |
| 71 | Mismatch repair_Homo sapiens_hsa03430 | 0.42124815 |
| 72 | Malaria_Homo sapiens_hsa05144 | 0.39994688 |
| 73 | Legionellosis_Homo sapiens_hsa05134 | 0.39035090 |
| 74 | Retinol metabolism_Homo sapiens_hsa00830 | 0.38845708 |
| 75 | Influenza A_Homo sapiens_hsa05164 | 0.37107810 |
| 76 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.37004703 |
| 77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.36176396 |
| 78 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 0.32595860 |
| 79 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.31164420 |
| 80 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.30141674 |
| 81 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.29081042 |
| 82 | Taste transduction_Homo sapiens_hsa04742 | 0.23292152 |
| 83 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.22105982 |
| 84 | Metabolic pathways_Homo sapiens_hsa01100 | 0.21998622 |
| 85 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.21000105 |
| 86 | HTLV-I infection_Homo sapiens_hsa05166 | 0.19306555 |
| 87 | Nicotine addiction_Homo sapiens_hsa05033 | 0.16859231 |
| 88 | Base excision repair_Homo sapiens_hsa03410 | 0.15983100 |
| 89 | Salivary secretion_Homo sapiens_hsa04970 | 0.15792441 |
| 90 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.15356561 |
| 91 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.15123860 |
| 92 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.13387980 |
| 93 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.12154247 |
| 94 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.11553485 |
| 95 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 0.09793837 |
| 96 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.09632696 |
| 97 | RNA transport_Homo sapiens_hsa03013 | 0.09020890 |
| 98 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.08488156 |
| 99 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.07649267 |
| 100 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.06432800 |

