CNP

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1fatty acid elongation (GO:0030497)7.84885495
2ensheathment of neurons (GO:0007272)7.64828951
3axon ensheathment (GO:0008366)7.64828951
4myelination (GO:0042552)7.57526872
5synaptic vesicle maturation (GO:0016188)7.23791360
6synaptic vesicle docking involved in exocytosis (GO:0016081)7.22586176
7glutamate secretion (GO:0014047)6.50580553
8long-chain fatty acid biosynthetic process (GO:0042759)6.22361599
9myelin maintenance (GO:0043217)5.97108204
10synaptic vesicle exocytosis (GO:0016079)5.95776341
11cellular potassium ion homeostasis (GO:0030007)5.94677017
12regulation of short-term neuronal synaptic plasticity (GO:0048172)5.65407894
13regulation of synaptic vesicle exocytosis (GO:2000300)5.51189006
14sodium ion export (GO:0071436)5.35639395
15locomotory exploration behavior (GO:0035641)5.27723961
16membrane depolarization during cardiac muscle cell action potential (GO:0086012)5.24996519
17positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.19695381
18negative regulation of neurotransmitter secretion (GO:0046929)5.17714374
19creatine metabolic process (GO:0006600)4.91069509
20neurotransmitter secretion (GO:0007269)4.82043734
21cholesterol biosynthetic process (GO:0006695)4.77566538
22regulation of synaptic vesicle transport (GO:1902803)4.74121569
23positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.68649078
24regulation of neuronal synaptic plasticity (GO:0048168)4.67420569
25negative regulation of neurotransmitter transport (GO:0051589)4.63514020
26postsynaptic membrane organization (GO:0001941)4.58735521
27regulation of collateral sprouting (GO:0048670)4.55899804
28potassium ion homeostasis (GO:0055075)4.50993243
29peptidyl-tyrosine autophosphorylation (GO:0038083)4.44690453
30establishment of mitochondrion localization (GO:0051654)4.41808500
31astrocyte development (GO:0014002)4.28017446
32potassium ion import (GO:0010107)4.25920670
33* oligodendrocyte differentiation (GO:0048709)4.25656810
34ionotropic glutamate receptor signaling pathway (GO:0035235)4.24563499
35negative regulation of synaptic transmission, GABAergic (GO:0032229)4.24169878
36negative regulation of protein localization to cell surface (GO:2000009)4.22993741
37glycerophospholipid catabolic process (GO:0046475)4.18976375
38apical protein localization (GO:0045176)4.15646961
39sterol biosynthetic process (GO:0016126)4.15103058
40photoreceptor cell differentiation (GO:0046530)4.13720640
41eye photoreceptor cell differentiation (GO:0001754)4.13720640
42asymmetric protein localization (GO:0008105)4.12228041
43peripheral nervous system axon ensheathment (GO:0032292)4.12112749
44myelination in peripheral nervous system (GO:0022011)4.12112749
45L-amino acid import (GO:0043092)4.06968144
46regulation of long-term neuronal synaptic plasticity (GO:0048169)4.06227211
47vocalization behavior (GO:0071625)4.00468710
48response to redox state (GO:0051775)3.99101572
49long-chain fatty-acyl-CoA biosynthetic process (GO:0035338)3.97680904
50exploration behavior (GO:0035640)3.95741606
51cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.94571410
52neurotransmitter transport (GO:0006836)3.92489736
53positive regulation of synapse maturation (GO:0090129)3.92257418
54response to methylmercury (GO:0051597)3.91836719
55* substantia nigra development (GO:0021762)3.89196863
56positive regulation of oligodendrocyte differentiation (GO:0048714)3.87819785
57presynaptic membrane organization (GO:0097090)3.86389119
58negative regulation of peptidyl-threonine phosphorylation (GO:0010801)3.84894878
59regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.81963813
60virion attachment to host cell (GO:0019062)3.80477167
61adhesion of symbiont to host cell (GO:0044650)3.80477167
62synaptic transmission, glutamatergic (GO:0035249)3.77389147
63regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act3.71769526
64isoprenoid biosynthetic process (GO:0008299)3.68837965
65long-chain fatty-acyl-CoA metabolic process (GO:0035336)3.68412524
66regulation of synaptic plasticity (GO:0048167)3.63650324
67response to lipoprotein particle (GO:0055094)3.62593564
68acidic amino acid transport (GO:0015800)3.62076767
69amyloid precursor protein metabolic process (GO:0042982)3.58591079
70neurotransmitter-gated ion channel clustering (GO:0072578)3.57805363
71import into cell (GO:0098657)3.57591452
72regulation of neurotransmitter levels (GO:0001505)3.56990277
73positive regulation of membrane potential (GO:0045838)3.55238388
74regulation of neurotransmitter secretion (GO:0046928)3.55233228
75regulation of excitatory postsynaptic membrane potential (GO:0060079)3.52494250
76presynaptic membrane assembly (GO:0097105)3.52344977
77membrane tubulation (GO:0097320)3.50191984
78regulation of glutamate receptor signaling pathway (GO:1900449)3.50007270
79regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.49543034
80negative regulation of axonogenesis (GO:0050771)3.49538108
81long-term synaptic potentiation (GO:0060291)3.47870698
82regulation of synapse structural plasticity (GO:0051823)3.47601543
83glutamate receptor signaling pathway (GO:0007215)3.44282492
84neuromuscular process controlling posture (GO:0050884)3.44091029
85regulation of neurotransmitter transport (GO:0051588)3.44033466
86fatty-acyl-CoA biosynthetic process (GO:0046949)3.43036355
87neuromuscular process controlling balance (GO:0050885)3.42491791
88neuron-neuron synaptic transmission (GO:0007270)3.41484869
89dendritic spine morphogenesis (GO:0060997)3.40258704
90cellular sodium ion homeostasis (GO:0006883)3.38929637
91protein palmitoylation (GO:0018345)3.38802956
92adult walking behavior (GO:0007628)3.38702890
93positive regulation of neurotransmitter secretion (GO:0001956)3.37113118
94positive regulation of neurotransmitter transport (GO:0051590)3.36938882
95astrocyte differentiation (GO:0048708)3.36488793
96gamma-aminobutyric acid transport (GO:0015812)3.34327770
97positive regulation of dendritic spine development (GO:0060999)3.33082840
98cellular response to epinephrine stimulus (GO:0071872)3.32503979
99cell communication by electrical coupling (GO:0010644)3.30989526
100regulation of postsynaptic membrane potential (GO:0060078)3.27511992
101regulation of dendritic spine development (GO:0060998)3.26696604
102regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.24851896
103transmission of nerve impulse (GO:0019226)3.24781581
104negative regulation of dendrite morphogenesis (GO:0050774)3.24197124
105L-glutamate transport (GO:0015813)3.23211650
106synaptic vesicle endocytosis (GO:0048488)3.21887903
107fatty-acyl-CoA metabolic process (GO:0035337)3.21113074
108regulation of dendritic spine morphogenesis (GO:0061001)3.19534956
109protein localization to synapse (GO:0035418)3.15949360
110regulation of vesicle fusion (GO:0031338)3.13604038
111GPI anchor biosynthetic process (GO:0006506)3.11771369
112proline transport (GO:0015824)3.10394702
113cerebellar Purkinje cell layer development (GO:0021680)3.10058279
114negative regulation of JUN kinase activity (GO:0043508)3.05621865
115auditory behavior (GO:0031223)3.04878644
116regulation of voltage-gated calcium channel activity (GO:1901385)3.04583329
117amino acid import (GO:0043090)3.04053610
118glycosylceramide metabolic process (GO:0006677)3.03517769
119regulation of ARF protein signal transduction (GO:0032012)3.03042608
120peripheral nervous system development (GO:0007422)3.02604547
121glial cell development (GO:0021782)3.00978141
122regulation of synaptic transmission (GO:0050804)3.00832601
123GPI anchor metabolic process (GO:0006505)3.00400376
124positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.00142924
125very long-chain fatty acid metabolic process (GO:0000038)2.99330848
126dendritic spine organization (GO:0097061)2.98391520
127long-term memory (GO:0007616)2.98312364
128neuron remodeling (GO:0016322)2.97883632
129limb bud formation (GO:0060174)2.97565298
130regulation of synapse maturation (GO:0090128)2.97162592
131axon development (GO:0061564)2.96135534
132peptidyl-cysteine modification (GO:0018198)2.95497750
133glycosphingolipid biosynthetic process (GO:0006688)2.95136272
134negative regulation of axon extension (GO:0030517)2.93654464
135enteric nervous system development (GO:0048484)2.92882572
136neuronal ion channel clustering (GO:0045161)2.92398503
137regulation of neurotransmitter uptake (GO:0051580)2.91142114
138response to epinephrine (GO:0071871)2.89498156
139neuron cell-cell adhesion (GO:0007158)2.89334243
140positive regulation of glial cell differentiation (GO:0045687)2.88790882
141magnesium ion transport (GO:0015693)2.88415985
142gamma-aminobutyric acid signaling pathway (GO:0007214)2.88303530
143detection of calcium ion (GO:0005513)2.87428421
144cellular response to monoamine stimulus (GO:0071868)2.86954239
145cellular response to catecholamine stimulus (GO:0071870)2.86954239
146regulation of synaptic transmission, glutamatergic (GO:0051966)2.86153150
147positive regulation of gliogenesis (GO:0014015)2.85980042
148membrane depolarization (GO:0051899)2.84797779
149response to auditory stimulus (GO:0010996)2.84534052
150nucleotide transmembrane transport (GO:1901679)2.81144647
151positive regulation of action potential (GO:0045760)2.79312492
152glycine transport (GO:0015816)2.77905552
153negative regulation of execution phase of apoptosis (GO:1900118)2.77552828
154cerebral cortex radially oriented cell migration (GO:0021799)2.76519405
155leukocyte migration involved in inflammatory response (GO:0002523)2.75844115
156response to hepatocyte growth factor (GO:0035728)2.74781748
157cellular response to hepatocyte growth factor stimulus (GO:0035729)2.74781748
158thioester biosynthetic process (GO:0035384)2.74644898
159acyl-CoA biosynthetic process (GO:0071616)2.74644898
160adhesion of symbiont to host (GO:0044406)2.74175886
161neuronal action potential propagation (GO:0019227)2.72848894
162regulation of lipoprotein metabolic process (GO:0050746)2.71245675
163response to lead ion (GO:0010288)2.68359503
164amyloid precursor protein catabolic process (GO:0042987)2.66277144
165preassembly of GPI anchor in ER membrane (GO:0016254)2.64871169
166nerve growth factor signaling pathway (GO:0038180)2.63787181
167iron coordination entity transport (GO:1901678)2.60560025
168response to catecholamine (GO:0071869)2.60169888
169response to monoamine (GO:0071867)2.60169888
170* neural nucleus development (GO:0048857)2.56692767
171regulation of interleukin-13 production (GO:0032656)2.56169955
172glutathione biosynthetic process (GO:0006750)2.53485383
173cerebellar granule cell differentiation (GO:0021707)2.53323288
174neurotransmitter uptake (GO:0001504)2.52462270
175positive regulation of pseudopodium assembly (GO:0031274)2.51117068
176protein localization to endosome (GO:0036010)2.50993955
177positive regulation of actin filament depolymerization (GO:0030836)2.49033725
178central nervous system myelination (GO:0022010)12.0849614
179axon ensheathment in central nervous system (GO:0032291)12.0849614

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.93810121
2GBX2_23144817_ChIP-Seq_PC3_Human3.05717162
3* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.81597509
4EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.66878061
5VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human2.55378101
6SOX9_22984422_ChIP-ChIP_TESTIS_Rat2.51023546
7THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse2.49174585
8CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.42959480
9SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.38652899
10SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.37065414
11E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse2.22567692
12JARID2_20064375_ChIP-Seq_MESCs_Mouse2.20393125
13EZH2_22144423_ChIP-Seq_EOC_Human2.17595708
14MTF2_20144788_ChIP-Seq_MESCs_Mouse2.12175180
15AR_21572438_ChIP-Seq_LNCaP_Human2.07714771
16TAF15_26573619_Chip-Seq_HEK293_Human2.07503827
17OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse2.06892794
18EZH2_27304074_Chip-Seq_ESCs_Mouse2.06276005
19RNF2_18974828_ChIP-Seq_MESCs_Mouse2.04995414
20EZH2_18974828_ChIP-Seq_MESCs_Mouse2.04995414
21IKZF1_21737484_ChIP-ChIP_HCT116_Human2.03529461
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.00845949
23TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.97323063
24SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.94342347
25EZH2_27294783_Chip-Seq_ESCs_Mouse1.91198324
26SUZ12_27294783_Chip-Seq_ESCs_Mouse1.91176532
27DROSHA_22980978_ChIP-Seq_HELA_Human1.90877220
28SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.83030908
29SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.80329898
30EED_16625203_ChIP-ChIP_MESCs_Mouse1.80062200
31JARID2_20075857_ChIP-Seq_MESCs_Mouse1.74308250
32DNAJC2_21179169_ChIP-ChIP_NT2_Human1.71968230
33RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.71383017
34ER_23166858_ChIP-Seq_MCF-7_Human1.66429760
35RNF2_27304074_Chip-Seq_ESCs_Mouse1.65494931
36RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.61331367
37ZFP57_27257070_Chip-Seq_ESCs_Mouse1.59348858
38CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.51364732
39ZFP281_18757296_ChIP-ChIP_E14_Mouse1.50684416
40CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.50675881
41KDM2B_26808549_Chip-Seq_K562_Human1.48782822
42CDX2_19796622_ChIP-Seq_MESCs_Mouse1.47155915
43* RARB_27405468_Chip-Seq_BRAIN_Mouse1.46781657
44RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.45543892
45TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.40766432
46SMAD3_21741376_ChIP-Seq_EPCs_Human1.40410293
47CTBP1_25329375_ChIP-Seq_LNCAP_Human1.40245453
48PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.39896139
49* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.39539490
50* TET1_21490601_ChIP-Seq_MESCs_Mouse1.35708845
51* TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.34489154
52PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.32936216
53CBX2_27304074_Chip-Seq_ESCs_Mouse1.32650150
54EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.32527631
55VDR_22108803_ChIP-Seq_LS180_Human1.29789343
56ERG_21242973_ChIP-ChIP_JURKAT_Human1.27154294
57REST_21632747_ChIP-Seq_MESCs_Mouse1.26729622
58ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.26136158
59TRIM28_21343339_ChIP-Seq_HEK293_Human1.25646418
60SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.25629160
61ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.25545706
62WT1_19549856_ChIP-ChIP_CCG9911_Human1.24473760
63WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.22974953
64PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.22733293
65P53_22127205_ChIP-Seq_FIBROBLAST_Human1.22377568
66SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.21420905
67* ZFP281_27345836_Chip-Seq_ESCs_Mouse1.19797999
68EOMES_21245162_ChIP-Seq_HESCs_Human1.18675848
69POU3F2_20337985_ChIP-ChIP_501MEL_Human1.17161705
70SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.16309122
71GATA1_26923725_Chip-Seq_HPCs_Mouse1.15321147
72NRF2_20460467_ChIP-Seq_MEFs_Mouse1.15074124
73NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.15074124
74SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.14440064
75CTNNB1_20460455_ChIP-Seq_HCT116_Human1.13656341
76REST_18959480_ChIP-ChIP_MESCs_Mouse1.13274138
77P300_19829295_ChIP-Seq_ESCs_Human1.11868978
78PIAS1_25552417_ChIP-Seq_VCAP_Human1.11582879
79AR_19668381_ChIP-Seq_PC3_Human1.10833530
80CTBP2_25329375_ChIP-Seq_LNCAP_Human1.10049404
81WT1_25993318_ChIP-Seq_PODOCYTE_Human1.09097308
82LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse1.08975987
83NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human1.08612114
84STAT3_23295773_ChIP-Seq_U87_Human1.08419185
85LXR_22292898_ChIP-Seq_THP-1_Human1.07129841
86TAL1_26923725_Chip-Seq_HPCs_Mouse1.06502287
87CTCF_27219007_Chip-Seq_Bcells_Human1.05911732
88SOX2_21211035_ChIP-Seq_LN229_Gbm1.05142197
89BMI1_23680149_ChIP-Seq_NPCS_Mouse1.02090809
90PPARD_23208498_ChIP-Seq_MDA-MB-231_Human1.01605162
91FUS_26573619_Chip-Seq_HEK293_Human1.01545119
92EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.01375375
93CMYC_18555785_Chip-Seq_ESCs_Mouse0.99067236
94HTT_18923047_ChIP-ChIP_STHdh_Human0.98894223
95LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97559139
96EP300_21415370_ChIP-Seq_HL-1_Mouse0.97448315
97MITF_21258399_ChIP-Seq_MELANOMA_Human0.96729059
98TCF4_23295773_ChIP-Seq_U87_Human0.95126733
99PRDM14_20953172_ChIP-Seq_ESCs_Human0.95085987
100TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.94608184
101YAP1_20516196_ChIP-Seq_MESCs_Mouse0.94507466
102PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93546200
103CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human0.92789520
104GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse0.92541178
105P300_18555785_Chip-Seq_ESCs_Mouse0.92260231
106GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.91206944
107* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.90884249
108SUZ12_18555785_Chip-Seq_ESCs_Mouse0.90808163
109TOP2B_26459242_ChIP-Seq_MCF-7_Human0.90755257
110AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.90026150
111GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.89691561
112NANOG_18555785_Chip-Seq_ESCs_Mouse0.89295741
113SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse0.88572378
114OLIG2_26023283_ChIP-Seq_AINV15_Mouse0.87693032
115EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse0.87374533
116MYC_19915707_ChIP-ChIP_AK7_Human0.87301498
117SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.86634588
118ESR2_21235772_ChIP-Seq_MCF-7_Human0.86631415
119RING1B_27294783_Chip-Seq_NPCs_Mouse0.85972698
120SMARCD1_25818293_ChIP-Seq_ESCs_Mouse0.85642304
121MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.85307882
122MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.85289842
123TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.84797020
124SMAD4_21799915_ChIP-Seq_A2780_Human0.84756252
125TP53_23651856_ChIP-Seq_MEFs_Mouse0.84678935
126TBL1_22424771_ChIP-Seq_293T_Human0.84494314
127RNF2_27304074_Chip-Seq_NSC_Mouse0.84433033
128NR3C1_23031785_ChIP-Seq_PC12_Mouse0.84094496
129* OCT4_19829295_ChIP-Seq_ESCs_Human0.84038437
130RING1B_27294783_Chip-Seq_ESCs_Mouse0.83587544
131SMAD4_21741376_ChIP-Seq_HESCs_Human0.83357434
132SMAD4_21741376_ChIP-Seq_ESCs_Human0.83054931
133ARNT_22903824_ChIP-Seq_MCF-7_Human0.82625695
134* SMAD3_21741376_ChIP-Seq_ESCs_Human0.82469875
135MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.82354641
136NR3C1_21868756_ChIP-Seq_MCF10A_Human0.82249363
137ESR1_22446102_ChIP-Seq_UTERUS_Mouse0.81981310
138DPY_21335234_ChIP-Seq_ESCs_Mouse0.81918447
139SMAD_19615063_ChIP-ChIP_OVARY_Human0.80571980
140SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.80024777
141SOX9_26525672_Chip-Seq_HEART_Mouse0.79903952
142KDM2B_26808549_Chip-Seq_SUP-B15_Human0.78705446
143DMRT1_23473982_ChIP-Seq_TESTES_Mouse0.76800196
144GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.76692253
145SMC4_20622854_ChIP-Seq_HELA_Human0.75841552

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1* MP0000920_abnormal_myelination5.86496007
2MP0003880_abnormal_central_pattern4.18877445
3MP0003690_abnormal_glial_cell3.50848792
4MP0003950_abnormal_plasma_membrane3.37635947
5MP0004270_analgesia3.30479109
6MP0004885_abnormal_endolymph3.10269665
7MP0005171_absent_coat_pigmentation3.07297780
8MP0001529_abnormal_vocalization2.88360509
9MP0003329_amyloid_beta_deposits2.86472021
10MP0004742_abnormal_vestibular_system2.68924901
11MP0001905_abnormal_dopamine_level2.60387161
12MP0004142_abnormal_muscle_tone2.56641466
13MP0001486_abnormal_startle_reflex2.56429557
14* MP0002272_abnormal_nervous_system2.55642561
15MP0004859_abnormal_synaptic_plasticity2.50328464
16* MP0003634_abnormal_glial_cell2.48845893
17MP0003136_yellow_coat_color2.41352840
18MP0009780_abnormal_chondrocyte_physiolo2.35326659
19* MP0002064_seizures2.26863972
20MP0001485_abnormal_pinna_reflex2.15768186
21MP0005409_darkened_coat_color1.94872016
22MP0003632_abnormal_nervous_system1.92931001
23MP0005451_abnormal_body_composition1.92757903
24MP0004381_abnormal_hair_follicle1.91229178
25MP0009745_abnormal_behavioral_response1.90854879
26* MP0000778_abnormal_nervous_system1.89215320
27* MP0002229_neurodegeneration1.88022857
28MP0003635_abnormal_synaptic_transmissio1.87781489
29MP0009046_muscle_twitch1.84388992
30MP0005423_abnormal_somatic_nervous1.80534896
31MP0005410_abnormal_fertilization1.80010466
32MP0002734_abnormal_mechanical_nocicepti1.77528448
33MP0003879_abnormal_hair_cell1.76064598
34MP0010678_abnormal_skin_adnexa1.67522253
35MP0000462_abnormal_digestive_system1.62870148
36MP0001984_abnormal_olfaction1.61628305
37MP0000383_abnormal_hair_follicle1.61020694
38MP0003787_abnormal_imprinting1.55252653
39MP0008569_lethality_at_weaning1.53326034
40MP0000604_amyloidosis1.51022913
41MP0003631_nervous_system_phenotype1.49009404
42MP0004134_abnormal_chest_morphology1.46938342
43MP0002572_abnormal_emotion/affect_behav1.41862953
44* MP0002882_abnormal_neuron_morphology1.41602700
45MP0001440_abnormal_grooming_behavior1.38873483
46* MP0000955_abnormal_spinal_cord1.38794995
47MP0005167_abnormal_blood-brain_barrier1.36438247
48MP0002063_abnormal_learning/memory/cond1.35190546
49MP0004043_abnormal_pH_regulation1.34710366
50MP0008260_abnormal_autophagy1.33760489
51* MP0002066_abnormal_motor_capabilities/c1.32575131
52MP0001970_abnormal_pain_threshold1.30342031
53MP0003633_abnormal_nervous_system1.28829084
54MP0003123_paternal_imprinting1.27515531
55MP0005551_abnormal_eye_electrophysiolog1.27492036
56MP0003806_abnormal_nucleotide_metabolis1.26754486
57MP0002067_abnormal_sensory_capabilities1.23181850
58MP0004147_increased_porphyrin_level1.22447121
59MP0005386_behavior/neurological_phenoty1.22200916
60MP0004924_abnormal_behavior1.22200916
61MP0001346_abnormal_lacrimal_gland1.22179954
62MP0001963_abnormal_hearing_physiology1.21676081
63MP0001299_abnormal_eye_distance/1.20648189
64MP0003075_altered_response_to1.20471053
65MP0005623_abnormal_meninges_morphology1.16775336
66MP0002733_abnormal_thermal_nociception1.13221725
67MP0003122_maternal_imprinting1.12762313
68MP0003172_abnormal_lysosome_physiology1.10803557
69* MP0002752_abnormal_somatic_nervous1.08810012
70MP0003283_abnormal_digestive_organ1.04313679
71MP0002909_abnormal_adrenal_gland1.02831571
72MP0005058_abnormal_lysosome_morphology1.00602366
73MP0002638_abnormal_pupillary_reflex0.99461389
74MP0005408_hypopigmentation0.96701203
75MP0001177_atelectasis0.95241672
76MP0001968_abnormal_touch/_nociception0.91520799
77MP0004145_abnormal_muscle_electrophysio0.90449027
78MP0001986_abnormal_taste_sensitivity0.88690586
79MP0005195_abnormal_posterior_eye0.88675620
80MP0001851_eye_inflammation0.87600240
81MP0003195_calcinosis0.86290967
82MP0000647_abnormal_sebaceous_gland0.85948658
83MP0000566_synostosis0.84898312
84MP0001661_extended_life_span0.82664178
85MP0002822_catalepsy0.82115747
86MP0000762_abnormal_tongue_morphology0.82057673
87* MP0002152_abnormal_brain_morphology0.81875107
88MP0003938_abnormal_ear_development0.78696906
89MP0006276_abnormal_autonomic_nervous0.77809644
90MP0009840_abnormal_foam_cell0.77724150
91MP0000015_abnormal_ear_pigmentation0.75793060
92MP0008874_decreased_physiological_sensi0.74967186
93MP0000467_abnormal_esophagus_morphology0.74411692
94MP0006082_CNS_inflammation0.73404863
95MP0000026_abnormal_inner_ear0.72468727
96MP0001502_abnormal_circadian_rhythm0.72422178
97MP0002736_abnormal_nociception_after0.72128271
98MP0004811_abnormal_neuron_physiology0.70948745
99MP0002735_abnormal_chemical_nociception0.70910370
100MP0000579_abnormal_nail_morphology0.70819120
101MP0005174_abnormal_tail_pigmentation0.70388755
102MP0002295_abnormal_pulmonary_circulatio0.70256538
103MP0001501_abnormal_sleep_pattern0.68251081
104MP0005645_abnormal_hypothalamus_physiol0.66151285
105MP0001348_abnormal_lacrimal_gland0.66145106
106MP0002069_abnormal_eating/drinking_beha0.66125911
107MP0003937_abnormal_limbs/digits/tail_de0.65582893
108MP0002184_abnormal_innervation0.65301738
109MP0002090_abnormal_vision0.65165353
110MP0002557_abnormal_social/conspecific_i0.64983882
111MP0010386_abnormal_urinary_bladder0.64483383
112MP0008438_abnormal_cutaneous_collagen0.64351682
113MP0005253_abnormal_eye_physiology0.63792643
114MP0005535_abnormal_body_temperature0.63540576
115MP0000372_irregular_coat_pigmentation0.62499724
116MP0000639_abnormal_adrenal_gland0.61860298
117MP0000569_abnormal_digit_pigmentation0.61444332
118MP0002089_abnormal_postnatal_growth/wei0.60802520
119MP0000003_abnormal_adipose_tissue0.60720512
120MP0005646_abnormal_pituitary_gland0.58900735
121* MP0000747_muscle_weakness0.58377893
122MP0002133_abnormal_respiratory_system0.56137788
123MP0005388_respiratory_system_phenotype0.56137788
124MP0003045_fibrosis0.48080122
125* MP0010769_abnormal_survival0.47860820
126MP0005166_decreased_susceptibility_to0.47731622
127MP0003956_abnormal_body_size0.46216796
128* MP0002082_postnatal_lethality0.46088684
129* MP0010770_preweaning_lethality0.46088684
130MP0004510_myositis0.45604168

Predicted human phenotypes

RankGene SetZ-score
1Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)6.57445467
2Degeneration of the lateral corticospinal tracts (HP:0002314)6.57445467
3Neurofibrillary tangles (HP:0002185)6.10452061
4Focal motor seizures (HP:0011153)6.01551826
5Cerebral hypomyelination (HP:0006808)5.50776324
6Sensory axonal neuropathy (HP:0003390)5.38126897
7Peripheral hypomyelination (HP:0007182)5.22131617
8Focal seizures (HP:0007359)5.18844030
9Abnormality of the corticospinal tract (HP:0002492)4.90215206
10Parakeratosis (HP:0001036)4.63555443
11Febrile seizures (HP:0002373)4.32429815
12Onion bulb formation (HP:0003383)4.31659755
13Cerebral inclusion bodies (HP:0100314)4.31640572
14Diplopia (HP:0000651)4.30765913
15Abnormality of binocular vision (HP:0011514)4.30765913
16Abnormal auditory evoked potentials (HP:0006958)4.24132303
17Epileptic encephalopathy (HP:0200134)4.17677288
18Supranuclear gaze palsy (HP:0000605)3.85558901
19Spastic gait (HP:0002064)3.78665785
20Alacrima (HP:0000522)3.73706708
21Congenital nonbullous ichthyosiform erythroderma (HP:0007479)3.68611301
22Generalized tonic-clonic seizures (HP:0002069)3.59552541
23Intention tremor (HP:0002080)3.57853855
24Abnormal eating behavior (HP:0100738)3.44028002
25Leukodystrophy (HP:0002415)3.42216436
26Dysmetria (HP:0001310)3.42038948
27Termporal pattern (HP:0011008)3.38403421
28Insidious onset (HP:0003587)3.38403421
29Mutism (HP:0002300)3.33464075
30CNS hypomyelination (HP:0003429)3.27480816
31Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)3.22144405
32Torticollis (HP:0000473)3.18731450
33Hemiparesis (HP:0001269)3.14337933
34Slow saccadic eye movements (HP:0000514)3.12980029
35Ankle clonus (HP:0011448)3.12042673
36Spastic paraparesis (HP:0002313)3.10759244
37Visual hallucinations (HP:0002367)3.09494200
38Segmental peripheral demyelination/remyelination (HP:0003481)3.05208105
39Akinesia (HP:0002304)3.04678042
40Myokymia (HP:0002411)3.02957731
41Decreased lacrimation (HP:0000633)2.97313887
42Truncal ataxia (HP:0002078)2.94699426
43Scanning speech (HP:0002168)2.92466498
44Papilledema (HP:0001085)2.89003651
45Postural instability (HP:0002172)2.88385351
46Obstructive sleep apnea (HP:0002870)2.85918858
47Premature skin wrinkling (HP:0100678)2.82543857
48Delusions (HP:0000746)2.81506693
49Abnormality of glycolysis (HP:0004366)2.80395596
50Increased serum pyruvate (HP:0003542)2.80395596
51Morphological abnormality of the inner ear (HP:0011390)2.79002988
52Tetraplegia (HP:0002445)2.77909108
53Focal dystonia (HP:0004373)2.75610155
54Hypoplastic pelvis (HP:0008839)2.74507434
55Dialeptic seizures (HP:0011146)2.72561221
56Urinary bladder sphincter dysfunction (HP:0002839)2.71052833
57Progressive cerebellar ataxia (HP:0002073)2.69098488
58Retinal dysplasia (HP:0007973)2.68707774
59Absence seizures (HP:0002121)2.68678215
60Apathy (HP:0000741)2.66833431
61Neuronal loss in central nervous system (HP:0002529)2.66748015
62Craniofacial dystonia (HP:0012179)2.64121953
63Hemiplegia (HP:0002301)2.62635609
64Annular pancreas (HP:0001734)2.61772252
65Congenital ichthyosiform erythroderma (HP:0007431)2.61483014
66Epileptiform EEG discharges (HP:0011182)2.60091159
67Rigidity (HP:0002063)2.57496402
68Depression (HP:0000716)2.56570117
69Insomnia (HP:0100785)2.56374489
70Stridor (HP:0010307)2.52923246
71Clumsiness (HP:0002312)2.52235297
72Thickened helices (HP:0000391)2.51600296
73Paraparesis (HP:0002385)2.50611204
74Anxiety (HP:0000739)2.50391455
75White forelock (HP:0002211)2.48185391
76Absent septum pellucidum (HP:0001331)2.45751196
77Pheochromocytoma (HP:0002666)2.45514939
78Heterochromia iridis (HP:0001100)2.43876368
79Dysdiadochokinesis (HP:0002075)2.43140045
80Bradykinesia (HP:0002067)2.43023206
81Anteriorly placed anus (HP:0001545)2.42568113
82Poor speech (HP:0002465)2.42460245
83Diminished motivation (HP:0000745)2.41532288
84Status epilepticus (HP:0002133)2.40596976
85Patchy hypopigmentation of hair (HP:0011365)2.39952789
86Sleep apnea (HP:0010535)2.39079497
87Increased circulating renin level (HP:0000848)2.34350671
88EEG with generalized epileptiform discharges (HP:0011198)2.34088984
89Ocular albinism (HP:0001107)2.31984817
90Cerebral hemorrhage (HP:0001342)2.30176641
91Foot dorsiflexor weakness (HP:0009027)2.27074469
92Spastic tetraparesis (HP:0001285)2.22935379
93Split foot (HP:0001839)2.21918701
94Iris hypopigmentation (HP:0007730)2.20823963
95Autoamputation (HP:0001218)2.20738245
96Lower limb muscle weakness (HP:0007340)2.20125368
97Hypsarrhythmia (HP:0002521)2.19487235
98Megalencephaly (HP:0001355)2.19161210
99Axonal loss (HP:0003447)2.18218772
100Hepatosplenomegaly (HP:0001433)2.15079547
101Impaired vibration sensation in the lower limbs (HP:0002166)2.14292586
102Hypoplasia of the iris (HP:0007676)2.12607196
103Action tremor (HP:0002345)2.11816278
104Decreased motor nerve conduction velocity (HP:0003431)2.10897576
105Neuroendocrine neoplasm (HP:0100634)2.10647877
106Poor eye contact (HP:0000817)2.10496754
107Amblyopia (HP:0000646)2.09670228
108Bowel incontinence (HP:0002607)2.08504784
109Aplasia involving bones of the extremities (HP:0009825)2.08383137
110Aplasia involving bones of the upper limbs (HP:0009823)2.08383137
111Aplasia of the phalanges of the hand (HP:0009802)2.08383137
112Rapidly progressive (HP:0003678)2.07487311
113Choreoathetosis (HP:0001266)2.05830174
114Abnormality of the septum pellucidum (HP:0007375)2.05517859
115Muscle fiber splitting (HP:0003555)2.05055885
116Abnormality of the foot musculature (HP:0001436)2.04103162
117Coronal craniosynostosis (HP:0004440)2.04026091
118Hypomagnesemia (HP:0002917)2.02897380
119Infantile muscular hypotonia (HP:0008947)2.02884399
120Limb dystonia (HP:0002451)2.01846021
121Abnormality of the periventricular white matter (HP:0002518)2.01290372
122Esophageal atresia (HP:0002032)1.98894508
123Peripheral demyelination (HP:0011096)1.98270312
124Clonus (HP:0002169)1.97675462
125Distal sensory impairment (HP:0002936)1.97255722
126Abnormality of the phalanges of the 2nd finger (HP:0009541)1.95476763
127Metabolic alkalosis (HP:0200114)1.95259043
128Abnormal large intestine physiology (HP:0012700)1.93021107
129Urinary incontinence (HP:0000020)1.92504149
130Postural tremor (HP:0002174)1.92252399
131Turricephaly (HP:0000262)1.90606931
132Polyphagia (HP:0002591)1.90543225
133Impaired smooth pursuit (HP:0007772)1.89973936
134Methylmalonic acidemia (HP:0002912)1.89947531
135Memory impairment (HP:0002354)1.86725152
136Gowers sign (HP:0003391)1.86196480
137Hammertoe (HP:0001765)1.86140187
138Blue irides (HP:0000635)1.84330281
139Atonic seizures (HP:0010819)1.83266823
140Partial agenesis of the corpus callosum (HP:0001338)1.82423772
141Abnormality of the salivary glands (HP:0010286)1.81782931
142Morphological abnormality of the pyramidal tract (HP:0002062)1.81381477
143Cupped ear (HP:0000378)1.79605467
144Partial duplication of thumb phalanx (HP:0009944)1.79189578
145Hypokalemic alkalosis (HP:0001949)1.79008812
146Urinary urgency (HP:0000012)1.78616127
147Synostosis involving the elbow (HP:0003938)1.78554292
148Humeroradial synostosis (HP:0003041)1.78554292
149Abnormality of the lower motor neuron (HP:0002366)1.78290942
150Abnormality of ocular smooth pursuit (HP:0000617)1.76429007
151Generalized myoclonic seizures (HP:0002123)1.75594453
152Paraplegia (HP:0010550)1.73390446
153Absent speech (HP:0001344)1.73165407
154Bundle branch block (HP:0011710)1.73092307
155Diminished movement (HP:0002374)1.71168298
156Renal Fanconi syndrome (HP:0001994)1.70467943
157Erythroderma (HP:0001019)1.68800569
158Abnormality of saccadic eye movements (HP:0000570)1.66927948
159Septo-optic dysplasia (HP:0100842)1.64652515

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK395.95739120
2OXSR14.36817176
3NTRK34.10974937
4PRPF4B3.84756431
5EPHB13.31040406
6DAPK23.20054025
7PKN13.01851111
8BCR2.91253213
9CDK192.62176273
10MINK12.29519944
11WNK42.26771756
12TNIK2.20963851
13FGFR22.16381715
14MET2.14463113
15LIMK12.12447138
16MAPKAPK52.11466153
17UHMK12.10746249
18PLK22.06919687
19CSNK1G32.00836734
20PBK1.95688025
21CSNK1A1L1.93076825
22NEK61.87253879
23WNK11.85566268
24TESK21.80047132
25CAMKK11.73178977
26RIPK11.68453957
27ROCK21.65080046
28CAMK2B1.60027463
29ICK1.54263416
30CSNK1G11.52702739
31CSNK1G21.51758769
32CLK11.47696245
33NTRK11.44684304
34GRK51.41179125
35SGK2231.38360130
36SGK4941.38360130
37TYRO31.32903414
38CAMK2D1.31386636
39DAPK11.29916318
40PAK61.29507582
41PNCK1.29420839
42EPHA41.26465288
43PRKCG1.23307788
44LATS21.22495198
45FGR1.21912829
46MST41.19783492
47CASK1.11544553
48CAMK11.10789963
49ALK1.08225648
50CAMK2G1.07262032
51PINK11.04702323
52MAP3K131.01192115
53DYRK20.93328124
54MARK10.91378919
55CDK140.91370279
56BRSK10.88616286
57PRKCQ0.85360808
58LMTK20.84161601
59CDK50.83021709
60MARK20.82429045
61SIK20.79480768
62ARAF0.79450365
63PRKD10.78918095
64CDK150.78585899
65DDR20.77861783
66CAMK2A0.76265539
67TESK10.75553769
68SGK20.74310489
69CDK180.73675958
70IRAK20.73369025
71CDK11A0.70728220
72SGK30.70664091
73STK380.69809824
74PAK30.68013081
75KSR20.67825010
76SGK10.67461667
77PDPK10.66824359
78MAPK120.65261749
79MAPK150.63362268
80PHKG10.63200030
81PHKG20.63200030
82MAPK130.61321985
83PRKCE0.60451315
84FYN0.59983158
85PRKCH0.57560345
86MAP3K40.56748215
87TNK20.56656786
88TRPM70.55828580
89FES0.52640858
90MUSK0.52017030
91PTK20.51352836
92CAMKK20.50826610
93NTRK20.49449702
94* RPS6KA30.47739830
95ERBB40.47483047
96FRK0.46935946
97CSNK1D0.45756983
98CSNK1A10.45303325
99DAPK30.43682841
100PRKG10.41924894
101PAK10.40985576
102ITK0.40214327
103BMPR1B0.39068800
104GSK3A0.38629099
105PRKD30.38230386
106BRAF0.38060658
107PDK10.36983213
108FER0.36866171
109STK110.35537464
110RIPK40.35443770
111IRAK10.35336287
112MAP3K20.34948021
113MAP3K110.34554506
114CCNB10.34465020
115FGFR30.34340110
116RPS6KA50.34299197
117PRKACB0.33977326
118PRKCA0.33500932
119PDK20.33068325
120MAP2K20.31842557
121CAMK40.31407651
122MAP3K90.31278115
123JAK10.30264253
124ROCK10.29185815
125PDGFRB0.27406102
126INSR0.27397026
127MAPK70.24984428
128PRKACA0.24582174
129MAPK100.23771084
130DMPK0.23603440
131BMX0.22906929
132ADRBK20.21723319
133ILK0.20785765
134BMPR20.20067324
135CSK0.19872198
136GRK70.19868156
137PRKCZ0.19342086
138SRC0.18660927
139DYRK1A0.17678482

Predicted pathways (KEGG)

RankGene SetZ-score
1Terpenoid backbone biosynthesis_Homo sapiens_hsa009005.64203060
2Steroid biosynthesis_Homo sapiens_hsa001004.67303169
3Fatty acid elongation_Homo sapiens_hsa000624.44860219
4Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.44390604
5Ether lipid metabolism_Homo sapiens_hsa005652.98641267
6Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005632.97918862
7Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049642.79959301
8Insulin secretion_Homo sapiens_hsa049112.71084835
9Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.55961453
10Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.50699345
11Vitamin B6 metabolism_Homo sapiens_hsa007502.35807902
12Taurine and hypotaurine metabolism_Homo sapiens_hsa004302.10390839
13Sulfur metabolism_Homo sapiens_hsa009202.01515972
14Axon guidance_Homo sapiens_hsa043601.98417827
15Oxidative phosphorylation_Homo sapiens_hsa001901.78607353
16Nitrogen metabolism_Homo sapiens_hsa009101.74024353
17Sphingolipid metabolism_Homo sapiens_hsa006001.71130999
18Protein export_Homo sapiens_hsa030601.62417485
19Aldosterone synthesis and secretion_Homo sapiens_hsa049251.60580204
20Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.55028603
21Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.48979114
22Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.44874221
23Linoleic acid metabolism_Homo sapiens_hsa005911.39824549
24GABAergic synapse_Homo sapiens_hsa047271.37170507
25beta-Alanine metabolism_Homo sapiens_hsa004101.35320802
26Calcium signaling pathway_Homo sapiens_hsa040201.33766974
27Glutamatergic synapse_Homo sapiens_hsa047241.32927533
28Butanoate metabolism_Homo sapiens_hsa006501.32257025
29Histidine metabolism_Homo sapiens_hsa003401.31509544
30alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.28129248
31Oxytocin signaling pathway_Homo sapiens_hsa049211.28033149
32Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.26717969
33Serotonergic synapse_Homo sapiens_hsa047261.24738232
34Parkinsons disease_Homo sapiens_hsa050121.24212046
35Alzheimers disease_Homo sapiens_hsa050101.22195601
36Renal cell carcinoma_Homo sapiens_hsa052111.14514853
37SNARE interactions in vesicular transport_Homo sapiens_hsa041301.12505017
38Arginine and proline metabolism_Homo sapiens_hsa003301.10717323
39Morphine addiction_Homo sapiens_hsa050321.08923772
40Bile secretion_Homo sapiens_hsa049761.06549376
41Long-term depression_Homo sapiens_hsa047301.05010525
42Estrogen signaling pathway_Homo sapiens_hsa049151.02739599
43Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.02678364
44Vibrio cholerae infection_Homo sapiens_hsa051101.01909182
45Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.00318908
46Melanogenesis_Homo sapiens_hsa049160.98715694
47Collecting duct acid secretion_Homo sapiens_hsa049660.98628340
48Thyroid hormone synthesis_Homo sapiens_hsa049180.97598576
49GnRH signaling pathway_Homo sapiens_hsa049120.97382235
50Sphingolipid signaling pathway_Homo sapiens_hsa040710.97210973
51Tight junction_Homo sapiens_hsa045300.95436197
52Glioma_Homo sapiens_hsa052140.95413424
53cGMP-PKG signaling pathway_Homo sapiens_hsa040220.92962426
54Endocytosis_Homo sapiens_hsa041440.91466564
55Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.86593327
56Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.85641377
57Phospholipase D signaling pathway_Homo sapiens_hsa040720.85078283
58Cocaine addiction_Homo sapiens_hsa050300.81289493
59Synaptic vesicle cycle_Homo sapiens_hsa047210.80156044
60Oocyte meiosis_Homo sapiens_hsa041140.78995663
61Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.77958474
62Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.77832642
63Inositol phosphate metabolism_Homo sapiens_hsa005620.76392315
64Circadian entrainment_Homo sapiens_hsa047130.75994085
65Lysosome_Homo sapiens_hsa041420.75483194
66Fatty acid metabolism_Homo sapiens_hsa012120.74714629
67Ras signaling pathway_Homo sapiens_hsa040140.73991154
68Rheumatoid arthritis_Homo sapiens_hsa053230.71341293
69Glutathione metabolism_Homo sapiens_hsa004800.68704079
70Arachidonic acid metabolism_Homo sapiens_hsa005900.66959819
71Glycerophospholipid metabolism_Homo sapiens_hsa005640.66424170
72Cholinergic synapse_Homo sapiens_hsa047250.66367425
73Vascular smooth muscle contraction_Homo sapiens_hsa042700.66300177
74Type II diabetes mellitus_Homo sapiens_hsa049300.65784011
75Carbohydrate digestion and absorption_Homo sapiens_hsa049730.65595733
76Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.65515746
77Rap1 signaling pathway_Homo sapiens_hsa040150.63243309
78ErbB signaling pathway_Homo sapiens_hsa040120.63215748
79Salivary secretion_Homo sapiens_hsa049700.62618750
80Dopaminergic synapse_Homo sapiens_hsa047280.61807440
81Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.60901547
82Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59847250
83Cardiac muscle contraction_Homo sapiens_hsa042600.59696142
84Nicotine addiction_Homo sapiens_hsa050330.59275170
85Gastric acid secretion_Homo sapiens_hsa049710.57542624
86Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.57503480
87Gap junction_Homo sapiens_hsa045400.54349276
88Phagosome_Homo sapiens_hsa041450.53790839
89Folate biosynthesis_Homo sapiens_hsa007900.53715370
90Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.53112201
91Ovarian steroidogenesis_Homo sapiens_hsa049130.53024995
92Phototransduction_Homo sapiens_hsa047440.52922590
93Autoimmune thyroid disease_Homo sapiens_hsa053200.51176533
94Huntingtons disease_Homo sapiens_hsa050160.50992821
95Dorso-ventral axis formation_Homo sapiens_hsa043200.49330173
96Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.47202940
97Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.46823533
98Neurotrophin signaling pathway_Homo sapiens_hsa047220.46510331
99Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.46463254
100Pancreatic secretion_Homo sapiens_hsa049720.46361587
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.46297442
102Propanoate metabolism_Homo sapiens_hsa006400.46039087
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45557335
104Fatty acid biosynthesis_Homo sapiens_hsa000610.44996169
105Mineral absorption_Homo sapiens_hsa049780.44992519
106Glucagon signaling pathway_Homo sapiens_hsa049220.44977217
107Steroid hormone biosynthesis_Homo sapiens_hsa001400.44419892
108Circadian rhythm_Homo sapiens_hsa047100.43183537
109Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.41759918
110Peroxisome_Homo sapiens_hsa041460.39813330
111Malaria_Homo sapiens_hsa051440.37575845
112VEGF signaling pathway_Homo sapiens_hsa043700.36617451
113Choline metabolism in cancer_Homo sapiens_hsa052310.36370999
114Arginine biosynthesis_Homo sapiens_hsa002200.35852802
115Renin secretion_Homo sapiens_hsa049240.35131165
116Metabolic pathways_Homo sapiens_hsa011000.34642690
117Hedgehog signaling pathway_Homo sapiens_hsa043400.33938905
118Phosphatidylinositol signaling system_Homo sapiens_hsa040700.33488095
119Chemokine signaling pathway_Homo sapiens_hsa040620.33276674
120cAMP signaling pathway_Homo sapiens_hsa040240.32987752
121Prion diseases_Homo sapiens_hsa050200.32552529
122Regulation of autophagy_Homo sapiens_hsa041400.31375688
123ABC transporters_Homo sapiens_hsa020100.30952873
124Amphetamine addiction_Homo sapiens_hsa050310.30760068
125Alcoholism_Homo sapiens_hsa050340.30445171
126mTOR signaling pathway_Homo sapiens_hsa041500.28421823
127Olfactory transduction_Homo sapiens_hsa047400.28193323
128Hippo signaling pathway_Homo sapiens_hsa043900.27706118
129Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.27689255
130Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.27604034
131Long-term potentiation_Homo sapiens_hsa047200.27337449
132Taste transduction_Homo sapiens_hsa047420.26978849
133MAPK signaling pathway_Homo sapiens_hsa040100.26401779
134Wnt signaling pathway_Homo sapiens_hsa043100.25744133
135Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.25540327
136Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.25493464

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