CNPPD1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.05205344
2antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.05205344
3antigen processing and presentation of endogenous antigen (GO:0019883)4.66797932
4positive regulation of gamma-delta T cell activation (GO:0046645)4.58727566
5detection of bacterium (GO:0016045)4.27576042
6detection of other organism (GO:0098543)4.19268519
7neutrophil activation involved in immune response (GO:0002283)4.12601470
8antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.92891758
9regulation of gamma-delta T cell differentiation (GO:0045586)3.67149696
10response to peptidoglycan (GO:0032494)3.65180388
11regulation of gamma-delta T cell activation (GO:0046643)3.49011698
12macrophage activation involved in immune response (GO:0002281)3.33190151
13regulation of mast cell degranulation (GO:0043304)3.31801110
14detection of external biotic stimulus (GO:0098581)3.26483463
15positive thymic T cell selection (GO:0045059)3.25958448
16B cell receptor signaling pathway (GO:0050853)3.25452813
17leukocyte aggregation (GO:0070486)3.24040524
18protoporphyrinogen IX metabolic process (GO:0046501)3.19903241
19T cell migration (GO:0072678)3.16432793
20positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.13754295
21Arp2/3 complex-mediated actin nucleation (GO:0034314)3.09362596
22positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.05044795
23regulation of antigen processing and presentation of peptide antigen (GO:0002583)3.04793525
24antigen processing and presentation via MHC class Ib (GO:0002475)3.04593927
25regulation of dendritic cell antigen processing and presentation (GO:0002604)3.04236544
263-UTR-mediated mRNA stabilization (GO:0070935)3.03322966
27modulation by virus of host process (GO:0019054)3.03304317
28respiratory burst (GO:0045730)3.01801826
29negative T cell selection (GO:0043383)2.98319449
30cellular response to virus (GO:0098586)2.97874218
31regulation of leukocyte degranulation (GO:0043300)2.96902717
32oxygen transport (GO:0015671)2.96408433
33fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)2.96029918
34regulation of myeloid leukocyte mediated immunity (GO:0002886)2.95502550
35modulation by symbiont of host cellular process (GO:0044068)2.95257817
36negative thymic T cell selection (GO:0045060)2.94674673
37positive regulation of B cell differentiation (GO:0045579)2.94430799
38regulation of antigen processing and presentation (GO:0002577)2.91754192
39regulation of mast cell activation involved in immune response (GO:0033006)2.91397474
40response to muramyl dipeptide (GO:0032495)2.90321259
41negative regulation of interleukin-12 production (GO:0032695)2.90060756
42detection of biotic stimulus (GO:0009595)2.86966053
43neutrophil activation (GO:0042119)2.84740342
44granulocyte activation (GO:0036230)2.82357551
45negative regulation of lymphocyte mediated immunity (GO:0002707)2.79777926
46negative regulation of leukocyte mediated immunity (GO:0002704)2.78487658
47negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)2.76593644
48cysteine metabolic process (GO:0006534)2.75537014
49B cell mediated immunity (GO:0019724)2.73907835
50hemoglobin metabolic process (GO:0020027)2.73574805
51interferon-gamma-mediated signaling pathway (GO:0060333)2.73429605
52regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.73354311
53thymic T cell selection (GO:0045061)2.72843203
54regulation of response to interferon-gamma (GO:0060330)2.72630268
55positive regulation of humoral immune response (GO:0002922)2.72376427
56modulation by symbiont of host defense response (GO:0052031)2.72144667
57modulation by organism of immune response of other organism involved in symbiotic interaction (GO:002.72144667
58modulation by organism of defense response of other organism involved in symbiotic interaction (GO:02.72144667
59positive regulation by organism of defense response of other organism involved in symbiotic interact2.72144667
60modulation by symbiont of host immune response (GO:0052553)2.72144667
61positive regulation by symbiont of host defense response (GO:0052509)2.72144667
62germinal center formation (GO:0002467)2.70724306
63cellular extravasation (GO:0045123)2.70471680
64regulation of T-helper 2 cell differentiation (GO:0045628)2.69738816
65myeloid cell activation involved in immune response (GO:0002275)2.69336920
66response to host immune response (GO:0052572)2.68270178
67response to immune response of other organism involved in symbiotic interaction (GO:0052564)2.68270178
68regulation of B cell differentiation (GO:0045577)2.67698318
69urea cycle (GO:0000050)2.67214934
70urea metabolic process (GO:0019627)2.67214934
71immunoglobulin mediated immune response (GO:0016064)2.65304898
72regulation of type I interferon-mediated signaling pathway (GO:0060338)2.64922760
73negative regulation of erythrocyte differentiation (GO:0045647)2.64480235
74regulation of B cell receptor signaling pathway (GO:0050855)2.64399348
75regulation of interferon-gamma-mediated signaling pathway (GO:0060334)2.64185812
76citrulline biosynthetic process (GO:0019240)2.63786804
77hepatocyte apoptotic process (GO:0097284)2.63524225
78positive regulation of Cdc42 GTPase activity (GO:0043089)2.62246411
79lipopolysaccharide-mediated signaling pathway (GO:0031663)2.61227360
80L-phenylalanine catabolic process (GO:0006559)2.61139708
81erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.61139708
82indole-containing compound catabolic process (GO:0042436)2.59701509
83indolalkylamine catabolic process (GO:0046218)2.59701509
84tryptophan catabolic process (GO:0006569)2.59701509
85plasma lipoprotein particle assembly (GO:0034377)2.58248797
86aromatic amino acid family catabolic process (GO:0009074)2.58042230
87positive regulation of type 2 immune response (GO:0002830)2.57437588
88NIK/NF-kappaB signaling (GO:0038061)2.56926747
89protein-lipid complex assembly (GO:0065005)2.56834110
90barbed-end actin filament capping (GO:0051016)2.55792754
91negative regulation of innate immune response (GO:0045824)2.55783025
92L-phenylalanine metabolic process (GO:0006558)2.55706310
93erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)2.55706310
94mannose metabolic process (GO:0006013)2.55701883
95amino sugar catabolic process (GO:0046348)2.55250769
96regulation of necroptotic process (GO:0060544)2.54816404
97defense response to protozoan (GO:0042832)2.53864496
98response to interleukin-15 (GO:0070672)2.52185897
99positive regulation of Rap GTPase activity (GO:0032854)2.50896538
100gas transport (GO:0015669)2.50498410
101response to type I interferon (GO:0034340)2.49687154
102response to host (GO:0075136)2.49066691
103response to host defenses (GO:0052200)2.49066691
104response to defenses of other organism involved in symbiotic interaction (GO:0052173)2.49066691
105amyloid precursor protein catabolic process (GO:0042987)2.48899642
106phospholipid efflux (GO:0033700)2.48789321
107positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)2.48143109
108megakaryocyte development (GO:0035855)2.47744358
109regulation of regulated secretory pathway (GO:1903305)2.47527508
110JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.47139528
111alpha-linolenic acid metabolic process (GO:0036109)2.46136654
112leukocyte degranulation (GO:0043299)2.46099629
113negative regulation of nitric oxide biosynthetic process (GO:0045019)2.46081200
114positive regulation of antigen processing and presentation (GO:0002579)2.45954220
115regulation of interferon-beta biosynthetic process (GO:0045357)2.45617433
116positive T cell selection (GO:0043368)2.44443444
117negative regulation of cytokine production involved in immune response (GO:0002719)2.44407958
118erythrocyte development (GO:0048821)2.44174844
119heme metabolic process (GO:0042168)2.42450601
120peptidyl-glutamic acid carboxylation (GO:0017187)2.42114392
121protein carboxylation (GO:0018214)2.42114392
122nitrogen cycle metabolic process (GO:0071941)2.41039965
123regulation of platelet aggregation (GO:0090330)2.40967069
124macrophage activation (GO:0042116)2.40750398
125tryptophan metabolic process (GO:0006568)2.39599719
126heme biosynthetic process (GO:0006783)2.39481855
127protoporphyrinogen IX biosynthetic process (GO:0006782)2.39168035
128cellular response to type I interferon (GO:0071357)2.39130483
129type I interferon signaling pathway (GO:0060337)2.39130483
130porphyrin-containing compound metabolic process (GO:0006778)2.38721010
131positive regulation of granulocyte differentiation (GO:0030854)2.38267400
132triglyceride-rich lipoprotein particle remodeling (GO:0034370)2.38022004
133T cell selection (GO:0045058)2.37661835
134regulation of cholesterol storage (GO:0010885)2.37192534
135tolerance induction (GO:0002507)2.33917644
136negative regulation of fibrinolysis (GO:0051918)2.33722068
137kynurenine metabolic process (GO:0070189)2.33296115
138valine metabolic process (GO:0006573)2.32460384
139regulation of T cell tolerance induction (GO:0002664)2.31739032
140regulation of superoxide anion generation (GO:0032928)2.31617682
141natural killer cell mediated immunity (GO:0002228)2.31279847
142natural killer cell mediated cytotoxicity (GO:0042267)2.31279847
143porphyrin-containing compound biosynthetic process (GO:0006779)2.30810697
144complement activation, alternative pathway (GO:0006957)2.30771434
145negative regulation of lipid storage (GO:0010888)2.30524649
146negative regulation of cell killing (GO:0031342)2.30149818
147negative regulation of leukocyte mediated cytotoxicity (GO:0001911)2.30149818
148leukocyte cell-cell adhesion (GO:0007159)2.29013616
149lymphocyte costimulation (GO:0031294)2.28142338
150regulation of humoral immune response (GO:0002920)2.28024084
151T cell costimulation (GO:0031295)2.27660616
152positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.27423916
153pentose-phosphate shunt (GO:0006098)2.26834373
154regulation of erythrocyte differentiation (GO:0045646)2.26116311
155positive regulation of erythrocyte differentiation (GO:0045648)2.24440788
156regulation of RIG-I signaling pathway (GO:0039535)2.23822821
157interferon-gamma production (GO:0032609)2.23587796
158positive regulation of lipoprotein lipase activity (GO:0051006)2.22882810

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.75003445
2IRF8_22096565_ChIP-ChIP_GC-B_Human3.59326901
3RXR_22158963_ChIP-Seq_LIVER_Mouse2.91838530
4MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.81785041
5PPARA_22158963_ChIP-Seq_LIVER_Mouse2.81753959
6IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.79366186
7STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.78460858
8IRF1_21803131_ChIP-Seq_MONOCYTES_Human2.70885143
9IRF8_21731497_ChIP-ChIP_J774_Mouse2.68186620
10LXR_22292898_ChIP-Seq_THP-1_Human2.42576811
11MYC_22102868_ChIP-Seq_BL_Human2.40014925
12FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.35415943
13GATA1_22025678_ChIP-Seq_K562_Human2.28250064
14EGR1_23403033_ChIP-Seq_LIVER_Mouse2.27617979
15NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse2.26656460
16SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse2.25396924
17SCL_19346495_ChIP-Seq_HPC-7_Human2.22782841
18SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.22750465
19VDR_21846776_ChIP-Seq_THP-1_Human2.18387082
20MYB_21317192_ChIP-Seq_ERMYB_Mouse2.15224983
21MAF_26560356_Chip-Seq_TH1_Human2.14971941
22IRF8_27001747_Chip-Seq_BMDM_Mouse2.08423394
23RUNX1_20887958_ChIP-Seq_HPC-7_Mouse2.08396526
24LXR_22158963_ChIP-Seq_LIVER_Mouse2.07567949
25* CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.99940753
26FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.92617701
27UTX_26944678_Chip-Seq_JUKART_Human1.92539625
28SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.89846935
29STAT4_19710469_ChIP-ChIP_TH1__Mouse1.89111423
30BRD4_27068464_Chip-Seq_AML-cells_Mouse1.89077845
31MYB_26560356_Chip-Seq_TH2_Human1.88704522
32NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.83414172
33ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.82901974
34NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.80108491
35MYB_26560356_Chip-Seq_TH1_Human1.79859745
36BP1_19119308_ChIP-ChIP_Hs578T_Human1.77600490
37RUNX1_22412390_ChIP-Seq_EML_Mouse1.74999654
38STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.71994264
39RUNX_20019798_ChIP-Seq_JUKART_Human1.69112542
40RACK7_27058665_Chip-Seq_MCF-7_Human1.68262884
41E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.68122503
42FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.67125496
43VDR_24763502_ChIP-Seq_THP-1_Human1.66725598
44TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.65776741
45GATA1_22383799_ChIP-Seq_G1ME_Mouse1.65543905
46TCF7_22412390_ChIP-Seq_EML_Mouse1.65401262
47* SPI1_23547873_ChIP-Seq_NB4_Human1.64503639
48MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.64313684
49* CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.62750086
50STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.62033926
51GATA1_19941827_ChIP-Seq_MEL_Mouse1.61918526
52CTCF_27219007_Chip-Seq_ERYTHROID_Human1.61323357
53RARG_19884340_ChIP-ChIP_MEFs_Mouse1.61259821
54MAF_26560356_Chip-Seq_TH2_Human1.59726213
55PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.59238098
56RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.57885208
57GATA2_22383799_ChIP-Seq_G1ME_Mouse1.55237039
58TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.53566145
59ELK3_25401928_ChIP-Seq_HUVEC_Human1.51730197
60EGR1_19374776_ChIP-ChIP_THP-1_Human1.49143437
61BCL6_27268052_Chip-Seq_Bcells_Human1.47899361
62FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.47660352
63SA1_27219007_Chip-Seq_ERYTHROID_Human1.44285880
64GATA1_19941826_ChIP-Seq_K562_Human1.43206787
65ELF1_20517297_ChIP-Seq_JURKAT_Human1.42191050
66VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.41821720
67BCOR_27268052_Chip-Seq_Bcells_Human1.40990934
68TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.40358576
69EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.38662708
70KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.38376812
71P68_20966046_ChIP-Seq_HELA_Human1.37911376
72GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.37513209
73STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.36381962
74STAT6_21828071_ChIP-Seq_BEAS2B_Human1.36074185
75KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.35555103
76TET1_21451524_ChIP-Seq_MESCs_Mouse1.33318062
77TP63_17297297_ChIP-ChIP_HaCaT_Human1.32229825
78GATA3_27048872_Chip-Seq_THYMUS_Human1.31822269
79TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.31263199
80Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.30191481
81SRY_22984422_ChIP-ChIP_TESTIS_Rat1.28414169
82SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.27090897
83KDM2B_26808549_Chip-Seq_K562_Human1.26920054
84CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.23969852
85LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.23614744
86KDM2B_26808549_Chip-Seq_JURKAT_Human1.23530590
87TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.23222543
88THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.22836104
89ELF1_17652178_ChIP-ChIP_JURKAT_Human1.21188058
90PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.20745819
91KDM2B_26808549_Chip-Seq_DND41_Human1.18355009
92DNAJC2_21179169_ChIP-ChIP_NT2_Human1.16844390
93GATA2_19941826_ChIP-Seq_K562_Human1.13977720
94LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.12254049
95PU_27001747_Chip-Seq_BMDM_Mouse1.11704560
96SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.11527995
97CTCF_21964334_ChIP-Seq_BJAB-B_Human1.08173149
98CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse1.08056370
99CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.06889034
100FOXM1_23109430_ChIP-Seq_U2OS_Human1.05838388
101CTCF_26484167_Chip-Seq_Bcells_Mouse1.05735468
102SMC4_20622854_ChIP-Seq_HELA_Human1.05006753
103EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.04796611
104SPI1_23127762_ChIP-Seq_K562_Human1.04218728
105GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.03501815
106SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.03029722
107PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.02998081
108CTCF_21964334_Chip-Seq_Bcells_Human1.02650992
109SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.02333355
110NOTCH1_21737748_ChIP-Seq_TLL_Human1.02052784
111NCOR1_26117541_ChIP-Seq_K562_Human1.02024260
112TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.01135612
113ZNF263_19887448_ChIP-Seq_K562_Human1.00771957
114CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.00698118
115ERG_20887958_ChIP-Seq_HPC-7_Mouse1.00590235
116KDM2B_26808549_Chip-Seq_SUP-B15_Human1.00564603
117KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.97606106
118PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse0.96489265
119TFEB_21752829_ChIP-Seq_HELA_Human0.94434561
120TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.94090976
121PU.1_20513432_ChIP-Seq_Bcells_Mouse0.93713375
122HOXB4_20404135_ChIP-ChIP_EML_Mouse0.93584520
123GATA2_21666600_ChIP-Seq_HMVEC_Human0.92898548
124ATF3_27146783_Chip-Seq_COLON_Human0.92168759
125CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse0.91347127
126CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.90138187
127FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human0.89215564
128SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.89193049
129FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.88652775

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005360_urolithiasis3.15065130
2MP0003656_abnormal_erythrocyte_physiolo2.83985200
3MP0002139_abnormal_hepatobiliary_system2.72827258
4MP0009840_abnormal_foam_cell2.69732125
5MP0001835_abnormal_antigen_presentation2.57027925
6MP0000685_abnormal_immune_system2.45462519
7MP0003436_decreased_susceptibility_to2.39715639
8MP0005671_abnormal_response_to2.39644646
9MP0003191_abnormal_cellular_cholesterol2.36664326
10MP0005365_abnormal_bile_salt2.33783313
11MP0003763_abnormal_thymus_physiology2.24210082
12MP0009785_altered_susceptibility_to2.22557306
13MP0003724_increased_susceptibility_to2.19446082
14MP0001800_abnormal_humoral_immune2.11882848
15MP0005464_abnormal_platelet_physiology2.07734916
16MP0001790_abnormal_immune_system2.03457056
17MP0005387_immune_system_phenotype2.03457056
18MP0009333_abnormal_splenocyte_physiolog1.97123149
19MP0005025_abnormal_response_to1.96989627
20MP0006082_CNS_inflammation1.93439940
21MP0005085_abnormal_gallbladder_physiolo1.91799934
22MP0002452_abnormal_antigen_presenting1.90300582
23MP0005000_abnormal_immune_tolerance1.90057510
24MP0002723_abnormal_immune_serum1.86866344
25MP0002420_abnormal_adaptive_immunity1.83073290
26MP0001819_abnormal_immune_cell1.81762571
27MP0003303_peritoneal_inflammation1.81112217
28MP0005058_abnormal_lysosome_morphology1.80796924
29MP0002419_abnormal_innate_immunity1.80744586
30MP0002166_altered_tumor_susceptibility1.76170441
31MP0002398_abnormal_bone_marrow1.75833454
32MP0008875_abnormal_xenobiotic_pharmacok1.74321541
33MP0005397_hematopoietic_system_phenotyp1.68001222
34MP0001545_abnormal_hematopoietic_system1.68001222
35MP0004947_skin_inflammation1.67187003
36MP0003300_gastrointestinal_ulcer1.66778845
37MP0005451_abnormal_body_composition1.66587041
38MP0002405_respiratory_system_inflammati1.63334880
39MP0005083_abnormal_biliary_tract1.61579779
40MP0000689_abnormal_spleen_morphology1.57229472
41MP0000716_abnormal_immune_system1.57143710
42MP0010155_abnormal_intestine_physiology1.49747036
43MP0002722_abnormal_immune_system1.49122388
44MP0001845_abnormal_inflammatory_respons1.47237358
45MP0003252_abnormal_bile_duct1.45938802
46MP0000609_abnormal_liver_physiology1.44324387
47MP0000465_gastrointestinal_hemorrhage1.43759582
48MP0008469_abnormal_protein_level1.41741897
49MP0009764_decreased_sensitivity_to1.40309364
50MP0002429_abnormal_blood_cell1.40302282
51MP0004510_myositis1.39403254
52MP0002148_abnormal_hypersensitivity_rea1.39104502
53MP0001873_stomach_inflammation1.38841653
54MP0005310_abnormal_salivary_gland1.38637136
55MP0010329_abnormal_lipoprotein_level1.38554229
56MP0003075_altered_response_to1.33990575
57MP0002138_abnormal_hepatobiliary_system1.33011662
58MP0003183_abnormal_peptide_metabolism1.32590941
59MP0001533_abnormal_skeleton_physiology1.27061925
60MP0002006_tumorigenesis1.23969766
61MP0005075_abnormal_melanosome_morpholog1.22833360
62MP0000858_altered_metastatic_potential1.19807954
63MP0002396_abnormal_hematopoietic_system1.19378442
64MP0003828_pulmonary_edema1.19266408
65MP0002998_abnormal_bone_remodeling1.13878058
66MP0002132_abnormal_respiratory_system1.12421700
67MP0002933_joint_inflammation1.11270813
68MP0000490_abnormal_crypts_of1.10490256
69MP0001666_abnormal_nutrient_absorption1.10027244
70MP0000703_abnormal_thymus_morphology1.08650660
71MP0000015_abnormal_ear_pigmentation1.06157937
72MP0009278_abnormal_bone_marrow1.05356096
73MP0003453_abnormal_keratinocyte_physiol1.05185298
74MP0009763_increased_sensitivity_to1.02501216
75MP0001853_heart_inflammation0.99342483
76MP0005166_decreased_susceptibility_to0.97877717
77MP0004808_abnormal_hematopoietic_stem0.97841485
78MP0003448_altered_tumor_morphology0.97401900
79MP0009643_abnormal_urine_homeostasis0.96837459
80MP0000604_amyloidosis0.96738815
81MP0001849_ear_inflammation0.96212180
82MP0000343_altered_response_to0.95635074
83MP0003705_abnormal_hypodermis_morpholog0.93086850
84MP0001663_abnormal_digestive_system0.92808424
85MP0000598_abnormal_liver_morphology0.92131219
86MP0008260_abnormal_autophagy0.91787519
87MP0002822_catalepsy0.90595149
88MP0005636_abnormal_mineral_homeostasis0.89891229
89MP0002136_abnormal_kidney_physiology0.89233180
90MP0003186_abnormal_redox_activity0.89101778
91MP0005332_abnormal_amino_acid0.88316504
92MP0005319_abnormal_enzyme/_coenzyme0.88023933
93MP0002019_abnormal_tumor_incidence0.86703585
94MP0003693_abnormal_embryo_hatching0.85612271
95MP0006054_spinal_hemorrhage0.83801747
96MP0008874_decreased_physiological_sensi0.83220211
97MP0005023_abnormal_wound_healing0.82218242
98MP0002118_abnormal_lipid_homeostasis0.82137021
99MP0003329_amyloid_beta_deposits0.81016287
100MP0008004_abnormal_stomach_pH0.80850177
101MP0005666_abnormal_adipose_tissue0.80652392
102MP0004381_abnormal_hair_follicle0.80529672
103MP0003866_abnormal_defecation0.79971236
104MP0005584_abnormal_enzyme/coenzyme_acti0.77605570
105MP0004858_abnormal_nervous_system0.77592759
106MP0003172_abnormal_lysosome_physiology0.75343459
107MP0000249_abnormal_blood_vessel0.74775158
108MP0005408_hypopigmentation0.73092677
109MP0005390_skeleton_phenotype0.72203607
110MP0003011_delayed_dark_adaptation0.72107541
111MP0003566_abnormal_cell_adhesion0.71725688
112MP0009765_abnormal_xenobiotic_induced0.71231529
113MP0004147_increased_porphyrin_level0.71006881
114MP0001851_eye_inflammation0.70826704
115MP0003690_abnormal_glial_cell0.70531593
116MP0003795_abnormal_bone_structure0.69609569
117MP0001243_abnormal_dermal_layer0.69607395
118MP0004019_abnormal_vitamin_homeostasis0.69492244
119MP0001764_abnormal_homeostasis0.69436067
120MP0003806_abnormal_nucleotide_metabolis0.67054360
121MP0009931_abnormal_skin_appearance0.66575487
122MP0003879_abnormal_hair_cell0.66447267
123MP0003221_abnormal_cardiomyocyte_apopto0.66233335
124MP0005381_digestive/alimentary_phenotyp0.62509473
125MP0005670_abnormal_white_adipose0.60705427
126MP0005076_abnormal_cell_differentiation0.59216832

Predicted human phenotypes

RankGene SetZ-score
1Eczematoid dermatitis (HP:0000976)3.80346050
2Recurrent abscess formation (HP:0002722)3.63716679
3Recurrent bacterial skin infections (HP:0005406)3.58917855
4Autoimmune thrombocytopenia (HP:0001973)3.46868476
5Petechiae (HP:0000967)3.42057166
6Poikilocytosis (HP:0004447)3.36221778
7Recurrent fungal infections (HP:0002841)3.35965731
8Recurrent gram-negative bacterial infections (HP:0005420)3.28862743
9Pustule (HP:0200039)3.25013228
10Nasal polyposis (HP:0100582)3.23793372
11Mediastinal lymphadenopathy (HP:0100721)3.23221455
12Myocardial infarction (HP:0001658)3.18030136
13Deep venous thrombosis (HP:0002625)3.17417666
14Recurrent bronchitis (HP:0002837)3.14116995
15Chronic otitis media (HP:0000389)3.07865345
16Orchitis (HP:0100796)3.07773336
17Hypochromic microcytic anemia (HP:0004840)3.06769067
18Abnormal platelet function (HP:0011869)3.02585312
19Impaired platelet aggregation (HP:0003540)3.02585312
20Recurrent viral infections (HP:0004429)3.02398186
21Abnormality of the nasal mucosa (HP:0000433)3.00111529
22Recurrent skin infections (HP:0001581)2.99865121
23Xanthomatosis (HP:0000991)2.93662282
24Gingival bleeding (HP:0000225)2.93173873
25Abnormality of liposaccharide metabolism (HP:0010968)2.92618244
26Abnormality of glycosphingolipid metabolism (HP:0004343)2.92618244
27Abnormality of glycolipid metabolism (HP:0010969)2.92618244
28Vacuolated lymphocytes (HP:0001922)2.87032008
29Prolonged bleeding time (HP:0003010)2.86999968
30Combined immunodeficiency (HP:0005387)2.86732627
31Increased cerebral lipofuscin (HP:0011813)2.84122750
32Epistaxis (HP:0000421)2.84014354
33Abnormality of aromatic amino acid family metabolism (HP:0004338)2.82939765
34Recurrent cutaneous fungal infections (HP:0011370)2.81768516
35Chronic mucocutaneous candidiasis (HP:0002728)2.81768516
36Abnormality of macrophages (HP:0004311)2.80780512
37Joint hemorrhage (HP:0005261)2.76862322
38Severe combined immunodeficiency (HP:0004430)2.73911689
39Hypochromic anemia (HP:0001931)2.73518544
40Tetraparesis (HP:0002273)2.71207480
41Hyperlipoproteinemia (HP:0010980)2.70536565
42Acanthocytosis (HP:0001927)2.69185924
43Polycythemia (HP:0001901)2.66835425
44T lymphocytopenia (HP:0005403)2.66427589
45Abnormality of T cell number (HP:0011839)2.61637858
46Hypertensive crisis (HP:0100735)2.59518940
47Optic neuritis (HP:0100653)2.58196403
48Retrobulbar optic neuritis (HP:0100654)2.58196403
49Gastrointestinal stroma tumor (HP:0100723)2.55648203
50Panhypogammaglobulinemia (HP:0003139)2.54596726
51Myositis (HP:0100614)2.52067780
52Systemic lupus erythematosus (HP:0002725)2.51292735
53Increased serum ferritin (HP:0003281)2.50763928
54Abnormality of T cells (HP:0002843)2.50526994
55Gingivitis (HP:0000230)2.50422164
56Elevated erythrocyte sedimentation rate (HP:0003565)2.50073757
57IgM deficiency (HP:0002850)2.49088449
58Encephalitis (HP:0002383)2.48989925
59Microcytic anemia (HP:0001935)2.47829562
60Spontaneous hematomas (HP:0007420)2.47698633
61Complement deficiency (HP:0004431)2.46954982
62Leukocytosis (HP:0001974)2.46635538
63Prolonged partial thromboplastin time (HP:0003645)2.46005152
64Abnormality of monocarboxylic acid metabolism (HP:0010996)2.45144085
65Loss of speech (HP:0002371)2.43394436
66Increased neuronal autofluorescent lipopigment (HP:0002074)2.41734663
67Interstitial pulmonary disease (HP:0006530)2.41522693
68Gastrointestinal infarctions (HP:0005244)2.40316410
69Abnormal delayed hypersensitivity skin test (HP:0002963)2.39569044
70Chest pain (HP:0100749)2.39477744
71Cholecystitis (HP:0001082)2.37333916
72Abnormal gallbladder physiology (HP:0012438)2.37333916
73Purpura (HP:0000979)2.36741156
74Agammaglobulinemia (HP:0004432)2.35853422
75Abnormality of iron homeostasis (HP:0011031)2.35359252
76Increased IgM level (HP:0003496)2.33306576
77Abnormality of T cell physiology (HP:0011840)2.33290261
78Abnormality of the heme biosynthetic pathway (HP:0010472)2.30682134
79Osteomyelitis (HP:0002754)2.30419651
80Menorrhagia (HP:0000132)2.29887714
81Cellulitis (HP:0100658)2.29777112
82Pulmonary infiltrates (HP:0002113)2.29499484
83Inflammation of the large intestine (HP:0002037)2.29063080
84Increased IgE level (HP:0003212)2.29049263
85Abnormality of complement system (HP:0005339)2.28816033
86Dysostosis multiplex (HP:0000943)2.28660386
87Hepatosplenomegaly (HP:0001433)2.25487183
88Gastrointestinal inflammation (HP:0004386)2.25394190
89Thrombocytosis (HP:0001894)2.24805929
90Vasculitis (HP:0002633)2.23471310
91Amyloidosis (HP:0011034)2.23125874
92Meningitis (HP:0001287)2.22691099
93Stomatitis (HP:0010280)2.22079458
94Abnormality of the common coagulation pathway (HP:0010990)2.20293742
95Colitis (HP:0002583)2.19506358
96Hyperbilirubinemia (HP:0002904)2.15895705
97Abnormal platelet volume (HP:0011876)2.13998814
98Thoracic kyphosis (HP:0002942)2.12924707
99IgG deficiency (HP:0004315)2.12739713
100Hemorrhage of the eye (HP:0011885)2.12658183
101Abnormal hemoglobin (HP:0011902)2.12568735
102Obstructive lung disease (HP:0006536)2.11897949
103Chronic obstructive pulmonary disease (HP:0006510)2.11897949
104Hypergammaglobulinemia (HP:0010702)2.10834300
105Abnormality of transition element cation homeostasis (HP:0011030)2.09923070
106Intracellular accumulation of autofluorescent lipopigment storage material (HP:0003204)2.09689471
107Cholelithiasis (HP:0001081)2.08478056
108Reticulocytosis (HP:0001923)2.07447592
109Glomerulonephritis (HP:0000099)2.07001326
110Abnormality of eosinophils (HP:0001879)2.06723336
111Lymphopenia (HP:0001888)2.06087013
112Urticaria (HP:0001025)2.05639485
113Intrahepatic cholestasis (HP:0001406)2.05416694
114Eosinophilia (HP:0001880)2.03216746
115Fatigue (HP:0012378)2.02990685
116Abnormality of the fingertips (HP:0001211)2.02327470
117Segmental peripheral demyelination/remyelination (HP:0003481)2.01099378
118Papilloma (HP:0012740)2.00218259
119Verrucae (HP:0200043)2.00218259
120Sepsis (HP:0100806)1.99511183
121Abnormality of sulfur amino acid metabolism (HP:0004339)1.99115899
122Keratoconjunctivitis sicca (HP:0001097)1.99072989
123Abnormality of glutamine family amino acid metabolism (HP:0010902)1.97958647
124Granulocytopenia (HP:0001913)1.97943171
125Thyroiditis (HP:0100646)1.97390236
126Recurrent sinusitis (HP:0011108)1.97011629
127Abnormality of mucopolysaccharide metabolism (HP:0011020)1.96864875
128Abnormality of polysaccharide metabolism (HP:0011012)1.96864875
129Abnormality of glycosaminoglycan metabolism (HP:0004371)1.96864875
130Episodic fever (HP:0001954)1.96558888
131Abnormality of cells of the lymphoid lineage (HP:0012140)1.96226865
132Periodontitis (HP:0000704)1.96005474
133Mitral stenosis (HP:0001718)1.95563429
134Urinary glycosaminoglycan excretion (HP:0003541)1.95140897
135Mucopolysacchariduria (HP:0008155)1.95140897
136Restrictive lung disease (HP:0002091)1.94400707
137Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.94204895
138Slow saccadic eye movements (HP:0000514)1.90409541
139Hypertriglyceridemia (HP:0002155)1.86734517
140Skin rash (HP:0000988)1.84795213
141Emphysema (HP:0002097)1.84533396
142Hemoptysis (HP:0002105)1.83319468
143Neuronal loss in central nervous system (HP:0002529)1.82896703
144Increased connective tissue (HP:0009025)1.81458009
145Vertebral compression fractures (HP:0002953)1.80638976
146Distal lower limb muscle weakness (HP:0009053)1.78615551

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K13.77532562
2PRPF4B3.37698944
3ERN13.14312221
4RIPK42.95986936
5TAOK32.85263645
6TYK22.50453252
7EEF2K2.42034490
8TBK12.41817149
9ZAP702.34442266
10FGFR42.30882923
11IKBKE2.30602367
12TXK2.28617601
13TAOK22.24770402
14NME22.10576934
15STK102.09374695
16BLK2.08020435
17TRIB32.07328449
18EIF2AK12.03491723
19IRAK41.94974229
20JAK31.93899120
21TGFBR21.82240886
22SMG11.75547263
23TNK21.71398974
24BTK1.69779185
25JAK11.60724449
26MAP3K141.59371584
27MAP3K101.58626403
28NLK1.51972541
29TESK21.46956866
30EPHB11.46136500
31PIM21.44778539
32IRAK31.44345645
33IKBKB1.44189826
34MAP3K11.42493123
35RPS6KA41.42284433
36TEC1.36927481
37FES1.36720366
38PIM11.34136526
39LRRK21.34015810
40ITK1.29410125
41KDR1.28307166
42SIK11.24895310
43TESK11.24589661
44SYK1.24533495
45GRK61.22948140
46HCK1.21339802
47KIT1.20331365
48EPHA31.15925390
49JAK21.15659424
50MARK21.10451025
51MAP3K61.08565325
52PKN21.07876644
53CSK1.03470291
54NEK91.02426452
55KSR21.01546192
56RIPK11.01320317
57LCK1.00418461
58ARAF0.97864550
59CHUK0.96402372
60FGR0.96073557
61ICK0.94992420
62DYRK1B0.93508505
63MAPK120.93000148
64CSF1R0.91932106
65TAOK10.91487228
66MAPK110.90399040
67BUB10.90143051
68MAPKAPK30.89287900
69MAP2K30.88089378
70BCKDK0.87731206
71STK40.86248348
72LYN0.83890907
73STK30.83666387
74MATK0.82952373
75MAP3K30.82237621
76CDK60.79582392
77NEK20.78802644
78PDPK10.76085149
79RPS6KL10.73095730
80RPS6KC10.73095730
81IRAK20.72667618
82CDK90.72605702
83CDC42BPA0.71632490
84PRKD20.70047030
85RPS6KA20.69690723
86FGFR30.69413450
87MOS0.66470151
88PDK10.66259317
89CDK40.65514729
90PTK60.64646800
91LATS10.64012310
92IRAK10.63243193
93MST40.61835273
94TRPM70.61725728
95STK240.61112232
96ABL10.60410879
97DYRK30.58860567
98MAPK40.55724274
99TTN0.55164154
100MAP2K20.55161524
101MAPK70.55156709
102MARK30.54269327
103HIPK20.50928067
104MAP3K130.49609541
105MAPKAPK20.49352722
106CDK120.49112455
107FLT30.48457612
108ACVR1B0.47527585
109ABL20.47308091
110SIK20.46782178
111FYN0.45518510
112MAP2K60.44759523
113MAP3K80.44322373
114PRKAA20.42060898
115CLK10.40877802
116PRKCQ0.39435250
117BRAF0.38084682
118TLK10.37573267
119MAP3K50.37493387
120TIE10.37431456
121CAMKK10.37357816
122SIK30.37046021
123PRKD10.36027058
124MAP3K70.34839114
125SGK30.34410973
126RPS6KA60.33764460
127STK380.33293318
128BMPR20.32841588
129ERBB40.32397650
130MAP3K110.31758523
131BMX0.31480707
132PAK40.30766997
133RET0.30261866
134RPS6KB20.27839234
135PDGFRB0.27197378

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053402.65830337
2Primary bile acid biosynthesis_Homo sapiens_hsa001202.43999199
3Staphylococcus aureus infection_Homo sapiens_hsa051502.34125861
4Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.28133467
5Autoimmune thyroid disease_Homo sapiens_hsa053202.25581276
6Caffeine metabolism_Homo sapiens_hsa002322.05684813
7Complement and coagulation cascades_Homo sapiens_hsa046101.87347162
8Vitamin B6 metabolism_Homo sapiens_hsa007501.77938865
9Leishmaniasis_Homo sapiens_hsa051401.76249223
10Intestinal immune network for IgA production_Homo sapiens_hsa046721.74845568
11NF-kappa B signaling pathway_Homo sapiens_hsa040641.73144280
12Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.73059054
13Measles_Homo sapiens_hsa051621.68550516
14Asthma_Homo sapiens_hsa053101.66957020
15Sulfur relay system_Homo sapiens_hsa041221.64634341
16Pentose and glucuronate interconversions_Homo sapiens_hsa000401.63793066
17Antigen processing and presentation_Homo sapiens_hsa046121.61056739
18Non-small cell lung cancer_Homo sapiens_hsa052231.50309446
19Type I diabetes mellitus_Homo sapiens_hsa049401.50185773
20B cell receptor signaling pathway_Homo sapiens_hsa046621.50162345
21Other glycan degradation_Homo sapiens_hsa005111.46601078
22Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.45573067
23Osteoclast differentiation_Homo sapiens_hsa043801.45465354
24Hematopoietic cell lineage_Homo sapiens_hsa046401.36131667
25ABC transporters_Homo sapiens_hsa020101.35231855
26Folate biosynthesis_Homo sapiens_hsa007901.35139203
27Histidine metabolism_Homo sapiens_hsa003401.31894881
28Phagosome_Homo sapiens_hsa041451.30022624
29Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.25651670
30Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.25433238
31Tryptophan metabolism_Homo sapiens_hsa003801.24664093
32Jak-STAT signaling pathway_Homo sapiens_hsa046301.24030993
33Pentose phosphate pathway_Homo sapiens_hsa000301.23293187
34T cell receptor signaling pathway_Homo sapiens_hsa046601.22663954
35Fatty acid degradation_Homo sapiens_hsa000711.21848004
36Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.20235209
37Herpes simplex infection_Homo sapiens_hsa051681.18776302
38Peroxisome_Homo sapiens_hsa041461.16372020
39VEGF signaling pathway_Homo sapiens_hsa043701.15467873
40Apoptosis_Homo sapiens_hsa042101.14788029
41RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.14317187
42Lysosome_Homo sapiens_hsa041421.12936478
43Toll-like receptor signaling pathway_Homo sapiens_hsa046201.12665052
44Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.12572746
45Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.11799398
46Arginine biosynthesis_Homo sapiens_hsa002201.10025350
47Graft-versus-host disease_Homo sapiens_hsa053321.09902292
48Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050141.08471634
49Rheumatoid arthritis_Homo sapiens_hsa053231.05559133
50Drug metabolism - other enzymes_Homo sapiens_hsa009831.05447498
51Acute myeloid leukemia_Homo sapiens_hsa052211.03857826
52Glycosaminoglycan degradation_Homo sapiens_hsa005311.03561178
53Toxoplasmosis_Homo sapiens_hsa051451.03335086
54Pancreatic cancer_Homo sapiens_hsa052121.02754967
55Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.02714713
56PPAR signaling pathway_Homo sapiens_hsa033201.01969617
57Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.01537388
58Malaria_Homo sapiens_hsa051441.00857127
59Influenza A_Homo sapiens_hsa051640.99865596
60Fructose and mannose metabolism_Homo sapiens_hsa000510.97990396
61Salmonella infection_Homo sapiens_hsa051320.96978683
62Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.94725993
63Chronic myeloid leukemia_Homo sapiens_hsa052200.94567326
64Selenocompound metabolism_Homo sapiens_hsa004500.91153341
65Retinol metabolism_Homo sapiens_hsa008300.90845720
66Neurotrophin signaling pathway_Homo sapiens_hsa047220.90006812
67beta-Alanine metabolism_Homo sapiens_hsa004100.89612359
68Endocytosis_Homo sapiens_hsa041440.89393055
69Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.88800398
70Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.86645178
71Hepatitis B_Homo sapiens_hsa051610.85365171
72Tuberculosis_Homo sapiens_hsa051520.85152168
73Pertussis_Homo sapiens_hsa051330.84627287
74Endometrial cancer_Homo sapiens_hsa052130.84136382
75NOD-like receptor signaling pathway_Homo sapiens_hsa046210.84132474
76Vitamin digestion and absorption_Homo sapiens_hsa049770.83894183
77Chemical carcinogenesis_Homo sapiens_hsa052040.83710113
78Shigellosis_Homo sapiens_hsa051310.83216820
79Legionellosis_Homo sapiens_hsa051340.83104938
80Renal cell carcinoma_Homo sapiens_hsa052110.82874355
81Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.81579429
82Hepatitis C_Homo sapiens_hsa051600.80332272
83Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.79585235
84Epstein-Barr virus infection_Homo sapiens_hsa051690.77160653
85TNF signaling pathway_Homo sapiens_hsa046680.73721020
86p53 signaling pathway_Homo sapiens_hsa041150.71235446
87Steroid hormone biosynthesis_Homo sapiens_hsa001400.71136262
88Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.71130827
89Allograft rejection_Homo sapiens_hsa053300.71109620
90Lysine degradation_Homo sapiens_hsa003100.70839660
91Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.70774143
92Leukocyte transendothelial migration_Homo sapiens_hsa046700.69589622
93Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.68819649
94Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.68784853
95African trypanosomiasis_Homo sapiens_hsa051430.68664288
96HTLV-I infection_Homo sapiens_hsa051660.64924689
97Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64653309
98Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.64485147
99Adipocytokine signaling pathway_Homo sapiens_hsa049200.64048447
100Viral myocarditis_Homo sapiens_hsa054160.64037396
101Sphingolipid signaling pathway_Homo sapiens_hsa040710.63185915
102Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.62990631
103Chemokine signaling pathway_Homo sapiens_hsa040620.62720627
104Galactose metabolism_Homo sapiens_hsa000520.62150664
105Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.60642685
106Carbohydrate digestion and absorption_Homo sapiens_hsa049730.60156455
107SNARE interactions in vesicular transport_Homo sapiens_hsa041300.59636822
108Insulin resistance_Homo sapiens_hsa049310.59588005
109Prion diseases_Homo sapiens_hsa050200.59223523
110Glycerolipid metabolism_Homo sapiens_hsa005610.59129761
111Phospholipase D signaling pathway_Homo sapiens_hsa040720.58612210
112Prolactin signaling pathway_Homo sapiens_hsa049170.58564400
113Phosphatidylinositol signaling system_Homo sapiens_hsa040700.58426829
114mTOR signaling pathway_Homo sapiens_hsa041500.58267798
115Insulin signaling pathway_Homo sapiens_hsa049100.58153943
116Cyanoamino acid metabolism_Homo sapiens_hsa004600.58034926
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.55442762
118Small cell lung cancer_Homo sapiens_hsa052220.55215687
119Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.54703706
120Choline metabolism in cancer_Homo sapiens_hsa052310.53788339
121Inositol phosphate metabolism_Homo sapiens_hsa005620.52808225
122HIF-1 signaling pathway_Homo sapiens_hsa040660.52574727
123Fatty acid metabolism_Homo sapiens_hsa012120.52404246
124Fat digestion and absorption_Homo sapiens_hsa049750.51912745
125Central carbon metabolism in cancer_Homo sapiens_hsa052300.51749835
126Nitrogen metabolism_Homo sapiens_hsa009100.51576802
127Longevity regulating pathway - mammal_Homo sapiens_hsa042110.49720042
128Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.49710172
129Platelet activation_Homo sapiens_hsa046110.49344028
130Bladder cancer_Homo sapiens_hsa052190.49191230
131Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.48240120
132GnRH signaling pathway_Homo sapiens_hsa049120.47071252
133Collecting duct acid secretion_Homo sapiens_hsa049660.46494962
134Notch signaling pathway_Homo sapiens_hsa043300.45165622
135AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.45108575
136Viral carcinogenesis_Homo sapiens_hsa052030.44244064
137Amoebiasis_Homo sapiens_hsa051460.43924863
138FoxO signaling pathway_Homo sapiens_hsa040680.43251689
139Transcriptional misregulation in cancer_Homo sapiens_hsa052020.42824993
140Starch and sucrose metabolism_Homo sapiens_hsa005000.41268001
141Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.40692467

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