CNPY2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1ribosomal small subunit assembly (GO:0000028)6.35272761
2SRP-dependent cotranslational protein targeting to membrane (GO:0006614)5.71868364
3cotranslational protein targeting to membrane (GO:0006613)5.61882083
4protein targeting to ER (GO:0045047)5.58823759
5viral transcription (GO:0019083)5.51867022
6translational termination (GO:0006415)5.34468557
7protein localization to endoplasmic reticulum (GO:0070972)5.32726230
8establishment of protein localization to endoplasmic reticulum (GO:0072599)5.29061178
9ribosomal small subunit biogenesis (GO:0042274)5.02683195
10chaperone-mediated protein transport (GO:0072321)4.97856528
11translational elongation (GO:0006414)4.69470521
12signal peptide processing (GO:0006465)4.65595104
13mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.53355975
14DNA deamination (GO:0045006)4.47621834
15mitochondrial respiratory chain complex assembly (GO:0033108)4.37513489
16establishment of protein localization to mitochondrial membrane (GO:0090151)4.32598428
17respiratory electron transport chain (GO:0022904)4.22779212
18electron transport chain (GO:0022900)4.20050566
19viral life cycle (GO:0019058)4.18858877
20Golgi transport vesicle coating (GO:0048200)4.13267985
21COPI coating of Golgi vesicle (GO:0048205)4.13267985
22cellular protein complex disassembly (GO:0043624)3.98859949
23translational initiation (GO:0006413)3.98840105
24nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.98200250
25cytochrome complex assembly (GO:0017004)3.93088051
26pseudouridine synthesis (GO:0001522)3.90424810
27translation (GO:0006412)3.90372146
28protein deneddylation (GO:0000338)3.89737518
29maturation of SSU-rRNA (GO:0030490)3.88624047
30water-soluble vitamin biosynthetic process (GO:0042364)3.79615418
31maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.79176135
32tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.73820830
33RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.73820830
34protein retention in ER lumen (GO:0006621)3.68689017
35protein targeting to membrane (GO:0006612)3.65966280
36mannosylation (GO:0097502)3.64775221
37proteasome assembly (GO:0043248)3.64322136
38L-phenylalanine metabolic process (GO:0006558)3.59666063
39erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.59666063
40rRNA modification (GO:0000154)3.48668345
41protein neddylation (GO:0045116)3.46473645
42protein targeting to mitochondrion (GO:0006626)3.46074642
43formation of translation preinitiation complex (GO:0001731)3.45909478
44erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.43524507
45L-phenylalanine catabolic process (GO:0006559)3.43524507
46aldehyde catabolic process (GO:0046185)3.42851932
47protein complex disassembly (GO:0043241)3.42449885
48peptidyl-histidine modification (GO:0018202)3.41549462
49ribosomal large subunit biogenesis (GO:0042273)3.36195542
50pteridine-containing compound biosynthetic process (GO:0042559)3.34021770
51pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.29497558
52establishment of protein localization to mitochondrion (GO:0072655)3.25443554
53macromolecular complex disassembly (GO:0032984)3.23883463
54protein-cofactor linkage (GO:0018065)3.21274718
55purine nucleoside triphosphate biosynthetic process (GO:0009145)3.16209045
56deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.15471097
57purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.15371050
58proline biosynthetic process (GO:0006561)3.14384011
59protein localization to mitochondrion (GO:0070585)3.12297412
60nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.10576809
61ATP biosynthetic process (GO:0006754)3.09729410
62tRNA processing (GO:0008033)3.09182428
63mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.08787113
64nucleoside transmembrane transport (GO:1901642)3.02496956
65exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.01837696
66antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.00610138
67base-excision repair, AP site formation (GO:0006285)3.00340114
68maturation of 5.8S rRNA (GO:0000460)2.97826770
69L-methionine biosynthetic process from methylthioadenosine (GO:0019509)2.93724431
70nuclear-transcribed mRNA catabolic process (GO:0000956)2.93027438
71hydrogen ion transmembrane transport (GO:1902600)2.92587519
72ATP synthesis coupled proton transport (GO:0015986)2.91421664
73energy coupled proton transport, down electrochemical gradient (GO:0015985)2.91421664
74protein maturation by protein folding (GO:0022417)2.90689646
75UTP biosynthetic process (GO:0006228)2.90379578
76ribonucleoside triphosphate biosynthetic process (GO:0009201)2.89928999
77branched-chain amino acid catabolic process (GO:0009083)2.88995227
78tRNA metabolic process (GO:0006399)2.88101399
79dolichol-linked oligosaccharide biosynthetic process (GO:0006488)2.87587973
80platelet dense granule organization (GO:0060155)2.86683156
81behavioral response to nicotine (GO:0035095)2.84802139
82negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)2.84534000
83glyoxylate metabolic process (GO:0046487)2.83856412
84antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.82902799
85mitochondrial transport (GO:0006839)2.81710261
86ubiquinone biosynthetic process (GO:0006744)2.81637778
87GDP-mannose metabolic process (GO:0019673)2.81382488
88preassembly of GPI anchor in ER membrane (GO:0016254)2.81351633
89rRNA processing (GO:0006364)2.80098717
90cellular ketone body metabolic process (GO:0046950)2.79790594
91serine family amino acid biosynthetic process (GO:0009070)2.79678259
92regulation of cellular amine metabolic process (GO:0033238)2.79395382
93anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.79342709
94UTP metabolic process (GO:0046051)2.78509258
95folic acid-containing compound biosynthetic process (GO:0009396)2.77978954
96pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.77895330
97mRNA catabolic process (GO:0006402)2.76091610
98oxidative phosphorylation (GO:0006119)2.75959271
99CTP biosynthetic process (GO:0006241)2.75894516
100CTP metabolic process (GO:0046036)2.75894516
101ribonucleoprotein complex biogenesis (GO:0022613)2.74325704
102regulation of cellular amino acid metabolic process (GO:0006521)2.73835094
103rRNA metabolic process (GO:0016072)2.73780259
104positive regulation of ubiquitin-protein transferase activity (GO:0051443)2.73434762
105proline metabolic process (GO:0006560)2.69447847
106L-methionine salvage (GO:0071267)2.69310109
107L-methionine biosynthetic process (GO:0071265)2.69310109
108amino acid salvage (GO:0043102)2.69310109
109DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:002.65756567
110nucleoside salvage (GO:0043174)2.65053448
111sulfur amino acid catabolic process (GO:0000098)2.64725199
112establishment of integrated proviral latency (GO:0075713)2.63890511
113aromatic amino acid family catabolic process (GO:0009074)2.60308838
114intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)2.59041223
115signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)2.59041223
116COPII vesicle coating (GO:0048208)2.58758555
117glycine metabolic process (GO:0006544)2.57427072
118respiratory chain complex IV assembly (GO:0008535)2.57407802
119negative regulation of ubiquitin-protein transferase activity (GO:0051444)2.56892585
120negative regulation of ligase activity (GO:0051352)2.56892585
121positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)2.56444603
122signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)2.56182768
123signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)2.56182768
124signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)2.56182768
125antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.56126103
126RNA catabolic process (GO:0006401)2.54617675
127tetrahydrofolate metabolic process (GO:0046653)2.54156893
128exocrine pancreas development (GO:0031017)2.50446385
129cellular component biogenesis (GO:0044085)2.49840996
130establishment of protein localization to membrane (GO:0090150)2.49594458
131protein targeting (GO:0006605)2.49131042
132GTP biosynthetic process (GO:0006183)2.49016150
133mitochondrial respiratory chain complex I assembly (GO:0032981)2.47985332
134NADH dehydrogenase complex assembly (GO:0010257)2.47985332
135mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.47985332
136metallo-sulfur cluster assembly (GO:0031163)2.47633961
137iron-sulfur cluster assembly (GO:0016226)2.47633961
138signal transduction involved in DNA integrity checkpoint (GO:0072401)2.46900563
139signal transduction involved in DNA damage checkpoint (GO:0072422)2.46900563
140intestinal cholesterol absorption (GO:0030299)2.46117060
141L-serine metabolic process (GO:0006563)2.45637038
142regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)2.45489721
143protein complex biogenesis (GO:0070271)2.43933022
144regulation of mitochondrial translation (GO:0070129)2.43729901
145signal transduction involved in cell cycle checkpoint (GO:0072395)2.43025271
146nucleobase-containing small molecule interconversion (GO:0015949)2.42118953
147cullin deneddylation (GO:0010388)2.42116792
148transcription elongation from RNA polymerase III promoter (GO:0006385)2.41965061
149termination of RNA polymerase III transcription (GO:0006386)2.41965061
150guanosine-containing compound biosynthetic process (GO:1901070)2.40193757
151response to interferon-beta (GO:0035456)2.38624393
152sulfur amino acid biosynthetic process (GO:0000097)2.37691428

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1MYC_18555785_ChIP-Seq_MESCs_Mouse4.00382202
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.94674783
3EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.70727007
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.67809357
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.66830236
6ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.47767823
7EST1_17652178_ChIP-ChIP_JURKAT_Human3.33190465
8JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.28009507
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.97895019
10* ETS1_20019798_ChIP-Seq_JURKAT_Human2.95518152
11ELF1_17652178_ChIP-ChIP_JURKAT_Human2.92421011
12CREB1_15753290_ChIP-ChIP_HEK293T_Human2.85077520
13MYC_18358816_ChIP-ChIP_MESCs_Mouse2.83045882
14CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.67443995
15E2F7_22180533_ChIP-Seq_HELA_Human2.66324577
16HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.53760778
17MYC_19030024_ChIP-ChIP_MESCs_Mouse2.45792326
18E2F1_18555785_ChIP-Seq_MESCs_Mouse2.38704858
19MYC_19079543_ChIP-ChIP_MESCs_Mouse2.37958993
20CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.32021550
21TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.30607236
22PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.25556129
23DCP1A_22483619_ChIP-Seq_HELA_Human2.22303195
24* XRN2_22483619_ChIP-Seq_HELA_Human2.21820709
25HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.18270090
26RXR_22158963_ChIP-Seq_LIVER_Mouse2.18161017
27EGR1_23403033_ChIP-Seq_LIVER_Mouse2.17915021
28CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.17866414
29SRF_21415370_ChIP-Seq_HL-1_Mouse2.12208741
30ZNF274_21170338_ChIP-Seq_K562_Hela2.09163510
31VDR_23849224_ChIP-Seq_CD4+_Human2.06045366
32PPARG_19300518_ChIP-PET_3T3-L1_Mouse2.05341901
33PPARA_22158963_ChIP-Seq_LIVER_Mouse2.01944610
34NELFA_20434984_ChIP-Seq_ESCs_Mouse1.99780244
35MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.95533756
36TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.89055038
37GABP_19822575_ChIP-Seq_HepG2_Human1.86885955
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.86415027
39* CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.82836338
40TTF2_22483619_ChIP-Seq_HELA_Human1.75330613
41FOXP3_21729870_ChIP-Seq_TREG_Human1.75314348
42ELK1_19687146_ChIP-ChIP_HELA_Human1.73010054
43FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.71868249
44HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.71161031
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.67179577
46FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.67003768
47ZFX_18555785_ChIP-Seq_MESCs_Mouse1.65922226
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.65842452
49FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.65042261
50HOXB4_20404135_ChIP-ChIP_EML_Mouse1.63742573
51FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.61781501
52PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.54687846
53YY1_21170310_ChIP-Seq_MESCs_Mouse1.49150089
54ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.46913194
55DMRT1_21621532_ChIP-ChIP_FETAL_Ovary1.40689742
56CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.39337040
57ELK1_22589737_ChIP-Seq_MCF10A_Human1.38318272
58MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.30583212
59SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.29824617
60CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.29374444
61HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.27541714
62E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.26214350
63LXR_22158963_ChIP-Seq_LIVER_Mouse1.25603934
64MYCN_18555785_ChIP-Seq_MESCs_Mouse1.25334698
65TP53_22573176_ChIP-Seq_HFKS_Human1.23919674
66POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.21900480
67BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.21396254
68E2F4_17652178_ChIP-ChIP_JURKAT_Human1.18175700
69EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.17868179
70NANOG_18555785_ChIP-Seq_MESCs_Mouse1.15408031
71VDR_22108803_ChIP-Seq_LS180_Human1.15204510
72CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.11459352
73HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.11431044
74CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.11270703
75STAT3_1855785_ChIP-Seq_MESCs_Mouse1.11057196
76NOTCH1_21737748_ChIP-Seq_TLL_Human1.10456916
77* TFEB_21752829_ChIP-Seq_HELA_Human1.09324532
78FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.08759524
79FOXP1_21924763_ChIP-Seq_HESCs_Human1.07825046
80TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06506010
81PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse1.06409107
82POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.04403367
83GFI1B_20887958_ChIP-Seq_HPC-7_Mouse1.04075330
84STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.03605094
85SOX17_20123909_ChIP-Seq_XEN_Mouse1.02896667
86* FOXA1_27270436_Chip-Seq_PROSTATE_Human1.01551266
87* FOXA1_25329375_ChIP-Seq_VCAP_Human1.01551266
88* AR_20517297_ChIP-Seq_VCAP_Human1.01105903
89TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.00179195
90KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.00153029
91CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human0.99827562
92EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.99522990
93CTCF_18555785_ChIP-Seq_MESCs_Mouse0.99227478
94SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.97802511
95IRF8_22096565_ChIP-ChIP_GC-B_Human0.96672145
96ERA_21632823_ChIP-Seq_H3396_Human0.96429713
97CIITA_25753668_ChIP-Seq_RAJI_Human0.96022025
98POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93420973
99YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse0.92889871
100* SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.92773531
101IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.92754895
102SOX2_18692474_ChIP-Seq_MEFs_Mouse0.92701671
103PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92666693
104AR_21909140_ChIP-Seq_LNCAP_Human0.91823392
105* E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.91582844
106RBPJ_21746931_ChIP-Seq_IB4-LCL_Human0.91341165
107* GATA3_21878914_ChIP-Seq_MCF-7_Human0.90590740
108SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.90037796
109ASH2L_23239880_ChIP-Seq_MESCs_Mouse0.88944207
110RARG_19884340_ChIP-ChIP_MEFs_Mouse0.88805558
111SRY_22984422_ChIP-ChIP_TESTIS_Rat0.88700895
112* NCOR_22424771_ChIP-Seq_293T_Human0.87365743
113OCT4_18692474_ChIP-Seq_MEFs_Mouse0.87340843
114ESRRB_18555785_ChIP-Seq_MESCs_Mouse0.86850827
115IRF1_19129219_ChIP-ChIP_H3396_Human0.86276153
116SOX2_18555785_ChIP-Seq_MESCs_Mouse0.85708288
117SPI1_23547873_ChIP-Seq_NB4_Human0.85267148
118EWS_26573619_Chip-Seq_HEK293_Human0.85242735
119TBX5_21415370_ChIP-Seq_HL-1_Mouse0.84660381
120TAF2_19829295_ChIP-Seq_ESCs_Human0.84646146
121NR4A2_19515692_ChIP-ChIP_MN9D_Mouse0.84293435
122* KDM5A_27292631_Chip-Seq_BREAST_Human0.84278934
123MYC_18940864_ChIP-ChIP_HL60_Human0.84140331
124P53_21459846_ChIP-Seq_SAOS-2_Human0.82622012
125IGF1R_20145208_ChIP-Seq_DFB_Human0.81734435
126HTT_18923047_ChIP-ChIP_STHdh_Human0.81007361
127HOXB7_26014856_ChIP-Seq_BT474_Human0.79738540
128SOX2_16153702_ChIP-ChIP_HESCs_Human0.79569421
129E2F1_21310950_ChIP-Seq_MCF-7_Human0.79508970
130MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.79484989
131CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.78951435

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system4.21805317
2MP0003806_abnormal_nucleotide_metabolis3.93719941
3MP0005365_abnormal_bile_salt3.42360983
4MP0005085_abnormal_gallbladder_physiolo3.03954365
5MP0005360_urolithiasis3.02272153
6MP0005083_abnormal_biliary_tract2.92192567
7MP0003186_abnormal_redox_activity2.85376787
8MP0003195_calcinosis2.76882941
9MP0005220_abnormal_exocrine_pancreas2.52820958
10MP0001666_abnormal_nutrient_absorption2.51555691
11MP0009379_abnormal_foot_pigmentation2.46800733
12MP0002876_abnormal_thyroid_physiology2.38693057
13MP0006292_abnormal_olfactory_placode2.38056510
14MP0000372_irregular_coat_pigmentation2.36102896
15MP0008875_abnormal_xenobiotic_pharmacok2.30787344
16MP0002163_abnormal_gland_morphology2.28613525
17MP0002102_abnormal_ear_morphology2.27831328
18MP0002837_dystrophic_cardiac_calcinosis2.17283047
19MP0002653_abnormal_ependyma_morphology2.11582363
20MP0003693_abnormal_embryo_hatching2.07745375
21MP0008438_abnormal_cutaneous_collagen2.03464942
22MP0003718_maternal_effect2.03314482
23MP0006054_spinal_hemorrhage2.02655846
24MP0004147_increased_porphyrin_level2.02141454
25MP0005084_abnormal_gallbladder_morpholo1.93822548
26MP0005551_abnormal_eye_electrophysiolog1.90370593
27MP0006072_abnormal_retinal_apoptosis1.87774771
28MP0002160_abnormal_reproductive_system1.85334577
29MP0008877_abnormal_DNA_methylation1.83127547
30MP0002736_abnormal_nociception_after1.82909578
31MP0003786_premature_aging1.80996858
32MP0008789_abnormal_olfactory_epithelium1.80609843
33MP0005332_abnormal_amino_acid1.80424467
34MP0001529_abnormal_vocalization1.75563360
35MP0005408_hypopigmentation1.75051749
36MP0001968_abnormal_touch/_nociception1.69578875
37MP0001905_abnormal_dopamine_level1.67022267
38MP0009840_abnormal_foam_cell1.66228186
39MP0001764_abnormal_homeostasis1.65681082
40MP0004957_abnormal_blastocyst_morpholog1.63482819
41MP0005503_abnormal_tendon_morphology1.60913387
42MP0010030_abnormal_orbit_morphology1.56535912
43MP0003011_delayed_dark_adaptation1.54253432
44MP0008872_abnormal_physiological_respon1.54209802
45MP0003252_abnormal_bile_duct1.52831934
46MP0005645_abnormal_hypothalamus_physiol1.52301651
47MP0010094_abnormal_chromosome_stability1.51111617
48MP0005646_abnormal_pituitary_gland1.48538062
49MP0003868_abnormal_feces_composition1.47557571
50MP0009643_abnormal_urine_homeostasis1.45452377
51MP0005389_reproductive_system_phenotype1.45274160
52MP0002938_white_spotting1.44494870
53MP0006035_abnormal_mitochondrial_morpho1.43199166
54MP0005253_abnormal_eye_physiology1.40819245
55MP0000678_abnormal_parathyroid_gland1.37352207
56MP0009046_muscle_twitch1.35726940
57MP0010329_abnormal_lipoprotein_level1.35178778
58MP0003787_abnormal_imprinting1.30343901
59MP0003122_maternal_imprinting1.30053764
60MP0005319_abnormal_enzyme/_coenzyme1.28078338
61MP0001984_abnormal_olfaction1.27346542
62MP0005499_abnormal_olfactory_system1.27279734
63MP0005394_taste/olfaction_phenotype1.27279734
64MP0009697_abnormal_copulation1.24140178
65MP0004142_abnormal_muscle_tone1.21409179
66MP0005410_abnormal_fertilization1.20482756
67MP0004019_abnormal_vitamin_homeostasis1.19764170
68MP0001944_abnormal_pancreas_morphology1.19522664
69MP0005636_abnormal_mineral_homeostasis1.19109576
70MP0003111_abnormal_nucleus_morphology1.12361489
71MP0005058_abnormal_lysosome_morphology1.10295770
72MP0003121_genomic_imprinting1.08665147
73MP0000613_abnormal_salivary_gland1.07716923
74MP0006036_abnormal_mitochondrial_physio1.05795407
75MP0002132_abnormal_respiratory_system1.05570562
76MP0002693_abnormal_pancreas_physiology1.05544142
77MP0000598_abnormal_liver_morphology1.05375591
78MP0008007_abnormal_cellular_replicative1.05105725
79MP0003191_abnormal_cellular_cholesterol1.04743209
80MP0003123_paternal_imprinting1.04309850
81MP0004782_abnormal_surfactant_physiolog1.03166334
82MP0002638_abnormal_pupillary_reflex1.02234217
83MP0000609_abnormal_liver_physiology1.02071878
84MP0006276_abnormal_autonomic_nervous1.01709533
85MP0002254_reproductive_system_inflammat0.99583932
86MP0008058_abnormal_DNA_repair0.99108338
87MP0005379_endocrine/exocrine_gland_phen0.98469365
88MP0000049_abnormal_middle_ear0.96724208
89MP0002138_abnormal_hepatobiliary_system0.93566386
90MP0000490_abnormal_crypts_of0.93506968
91MP0008469_abnormal_protein_level0.93130224
92MP0001986_abnormal_taste_sensitivity0.91390551
93MP0003724_increased_susceptibility_to0.91227400
94MP0008932_abnormal_embryonic_tissue0.90805594
95MP0004133_heterotaxia0.90559565
96MP0001919_abnormal_reproductive_system0.90364726
97MP0002210_abnormal_sex_determination0.89531770
98MP0001929_abnormal_gametogenesis0.89287644
99MP0000681_abnormal_thyroid_gland0.88033774
100MP0001542_abnormal_bone_strength0.86264524
101MP0003077_abnormal_cell_cycle0.85417626
102MP0003942_abnormal_urinary_system0.84713013
103MP0008995_early_reproductive_senescence0.83709804
104MP0003436_decreased_susceptibility_to0.82692638
105MP0002234_abnormal_pharynx_morphology0.82680157
106MP0002095_abnormal_skin_pigmentation0.81636695
107MP0010386_abnormal_urinary_bladder0.81495560
108MP0001756_abnormal_urination0.81280672
109MP0000631_abnormal_neuroendocrine_gland0.80853534
110MP0001485_abnormal_pinna_reflex0.80273460
111MP0001853_heart_inflammation0.80269533
112MP0005023_abnormal_wound_healing0.80203765
113MP0000653_abnormal_sex_gland0.79789071
114MP0005376_homeostasis/metabolism_phenot0.79227856
115MP0004264_abnormal_extraembryonic_tissu0.79174821
116MP0005275_abnormal_skin_tensile0.79138646
117MP0003137_abnormal_impulse_conducting0.78674044
118MP0002295_abnormal_pulmonary_circulatio0.78572296
119MP0003959_abnormal_lean_body0.78041300
120MP0001145_abnormal_male_reproductive0.77938965
121MP0000858_altered_metastatic_potential0.77906767
122MP0000163_abnormal_cartilage_morphology0.77269515
123MP0002909_abnormal_adrenal_gland0.77017321
124MP0000647_abnormal_sebaceous_gland0.76996125
125MP0010368_abnormal_lymphatic_system0.76689211
126MP0002118_abnormal_lipid_homeostasis0.75348690
127MP0003136_yellow_coat_color0.75321452
128MP0002090_abnormal_vision0.74845384
129MP0009745_abnormal_behavioral_response0.74114468
130MP0003279_aneurysm0.74108001
131MP0003698_abnormal_male_reproductive0.74045031
132MP0004043_abnormal_pH_regulation0.73576180
133MP0001293_anophthalmia0.73355884
134MP0005075_abnormal_melanosome_morpholog0.72580771
135MP0003878_abnormal_ear_physiology0.72189533
136MP0005377_hearing/vestibular/ear_phenot0.72189533
137MP0005195_abnormal_posterior_eye0.71797596
138MP0003638_abnormal_response/metabolism_0.71022820
139MP0009053_abnormal_anal_canal0.70251305
140MP0000358_abnormal_cell_content/0.68859069
141MP0002282_abnormal_trachea_morphology0.68629403
142MP0001270_distended_abdomen0.68076761
143MP0005508_abnormal_skeleton_morphology0.66808667
144MP0000538_abnormal_urinary_bladder0.66597694
145MP0009642_abnormal_blood_homeostasis0.65836834
146MP0009763_increased_sensitivity_to0.65039792
147MP0005584_abnormal_enzyme/coenzyme_acti0.64606922
148MP0001243_abnormal_dermal_layer0.64305189
149MP0003119_abnormal_digestive_system0.62872061
150MP0009384_cardiac_valve_regurgitation0.62805534
151MP0002060_abnormal_skin_morphology0.62454422
152MP0001835_abnormal_antigen_presentation0.62447521
153MP0009765_abnormal_xenobiotic_induced0.61931928
154MP0005390_skeleton_phenotype0.61924460
155MP0005164_abnormal_response_to0.61909788
156MP0001533_abnormal_skeleton_physiology0.61822391
157MP0009333_abnormal_splenocyte_physiolog0.61286556
158MP0002135_abnormal_kidney_morphology0.61243054
159MP0009785_altered_susceptibility_to0.60816797
160MP0004272_abnormal_basement_membrane0.60457232
161MP0003795_abnormal_bone_structure0.59870715

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of aromatic amino acid family metabolism (HP:0004338)4.73521252
2Abnormality of cells of the erythroid lineage (HP:0012130)4.07086441
3Abnormal number of erythroid precursors (HP:0012131)3.84458854
4Reticulocytopenia (HP:0001896)3.70246271
5Abnormality of the intrinsic pathway (HP:0010989)3.36683347
6Hepatic necrosis (HP:0002605)3.29125581
7Hypoglycemic coma (HP:0001325)3.26652666
8Prolonged partial thromboplastin time (HP:0003645)3.25440695
9Type I transferrin isoform profile (HP:0003642)3.20380397
10Abnormality of monocarboxylic acid metabolism (HP:0010996)3.20112208
11Macrocytic anemia (HP:0001972)3.14024122
12Abnormality of alanine metabolism (HP:0010916)3.03550260
13Hyperalaninemia (HP:0003348)3.03550260
14Abnormality of pyruvate family amino acid metabolism (HP:0010915)3.03550260
15Intrahepatic cholestasis (HP:0001406)2.99668081
16Reduced antithrombin III activity (HP:0001976)2.96830571
17Pancreatic cysts (HP:0001737)2.96501590
18Hepatocellular necrosis (HP:0001404)2.96349423
19Mitochondrial inheritance (HP:0001427)2.94625897
20Lipid accumulation in hepatocytes (HP:0006561)2.92072136
21Acute encephalopathy (HP:0006846)2.87931401
22Acute necrotizing encephalopathy (HP:0006965)2.83023736
23Abnormality of midbrain morphology (HP:0002418)2.82537155
24Molar tooth sign on MRI (HP:0002419)2.82537155
25Generalized aminoaciduria (HP:0002909)2.82529760
26Hypobetalipoproteinemia (HP:0003563)2.81906263
27Pancreatic fibrosis (HP:0100732)2.75870711
28Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.75718414
29Decreased activity of mitochondrial respiratory chain (HP:0008972)2.75718414
30Renal Fanconi syndrome (HP:0001994)2.73733172
31Aplastic anemia (HP:0001915)2.73094790
32Aplasia/Hypoplasia of the sacrum (HP:0008517)2.70249131
33Increased hepatocellular lipid droplets (HP:0006565)2.69459309
34Respiratory failure (HP:0002878)2.67311155
35Abnormality of long-chain fatty-acid metabolism (HP:0010964)2.67018102
36Abnormal mitochondria in muscle tissue (HP:0008316)2.65146034
37Beaking of vertebral bodies (HP:0004568)2.61873470
38Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.58836227
39Abnormal protein N-linked glycosylation (HP:0012347)2.58836227
40Abnormal protein glycosylation (HP:0012346)2.58836227
41Abnormal glycosylation (HP:0012345)2.58836227
42Fat malabsorption (HP:0002630)2.58700385
43Abnormality of the common coagulation pathway (HP:0010990)2.58241099
44Methylmalonic aciduria (HP:0012120)2.56768631
45Abnormal hemoglobin (HP:0011902)2.56049551
46Increased CSF lactate (HP:0002490)2.54996928
47Vacuolated lymphocytes (HP:0001922)2.53897159
48Pallor (HP:0000980)2.52987312
49Delayed CNS myelination (HP:0002188)2.50324380
50Optic disc pallor (HP:0000543)2.50311226
51Cerebral edema (HP:0002181)2.49180021
52Abnormality of urine glucose concentration (HP:0011016)2.48576940
53Glycosuria (HP:0003076)2.48576940
54Late onset (HP:0003584)2.47064657
55Increased intramyocellular lipid droplets (HP:0012240)2.45078696
56Opisthotonus (HP:0002179)2.45044466
57Increased muscle lipid content (HP:0009058)2.43904516
58Hypoglycemic seizures (HP:0002173)2.42032347
59Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.40262206
60Poor head control (HP:0002421)2.39370983
61Steatorrhea (HP:0002570)2.37139057
62Abnormality of fatty-acid metabolism (HP:0004359)2.36960697
63Decreased electroretinogram (ERG) amplitude (HP:0000654)2.32589307
64Medial flaring of the eyebrow (HP:0010747)2.31978127
65Microretrognathia (HP:0000308)2.31908869
66Increased serum pyruvate (HP:0003542)2.29573782
67True hermaphroditism (HP:0010459)2.29561626
68Abnormality of serum amino acid levels (HP:0003112)2.28235490
69Multiple enchondromatosis (HP:0005701)2.26290289
70CNS demyelination (HP:0007305)2.24921242
71Abnormal tarsal ossification (HP:0008369)2.22479859
72Ketosis (HP:0001946)2.22033488
73Increased serum lactate (HP:0002151)2.21959942
74Ketoacidosis (HP:0001993)2.21327826
75Redundant skin (HP:0001582)2.20096597
76Biconcave vertebral bodies (HP:0004586)2.19331893
77Symptomatic seizures (HP:0011145)2.18272454
78Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.18029703
79Type II lissencephaly (HP:0007260)2.18005044
80Methylmalonic acidemia (HP:0002912)2.17398385
81Lethargy (HP:0001254)2.16608279
82Abnormality of dicarboxylic acid metabolism (HP:0010995)2.16416248
83Dicarboxylic aciduria (HP:0003215)2.16416248
84Hyperphosphaturia (HP:0003109)2.16167321
85Oral leukoplakia (HP:0002745)2.15943598
86Exertional dyspnea (HP:0002875)2.15312905
87Abnormal cartilage morphology (HP:0002763)2.15287225
88Bile duct proliferation (HP:0001408)2.10786417
89Abnormal biliary tract physiology (HP:0012439)2.10786417
90Lactic acidosis (HP:0003128)2.10416003
91Leukodystrophy (HP:0002415)2.10333481
92Thrombocytosis (HP:0001894)2.08158561
93Abnormality of glycolysis (HP:0004366)2.06986036
94Abnormality of pyrimidine metabolism (HP:0004353)2.06684112
95Nausea (HP:0002018)2.06513594
96Abnormality of serine family amino acid metabolism (HP:0010894)2.06194422
97Abnormality of glycine metabolism (HP:0010895)2.06194422
98Congenital stationary night blindness (HP:0007642)2.03101880
99Hyperglycinemia (HP:0002154)2.02536995
100Abnormality of the anterior horn cell (HP:0006802)2.01994631
101Degeneration of anterior horn cells (HP:0002398)2.01994631
102Progressive macrocephaly (HP:0004481)2.01971741
103Cerebral hypomyelination (HP:0006808)2.01586833
10411 pairs of ribs (HP:0000878)2.00519228
105Deep venous thrombosis (HP:0002625)2.00124994
106Hyperammonemia (HP:0001987)1.99963433
107Conjugated hyperbilirubinemia (HP:0002908)1.98449985
108Nephronophthisis (HP:0000090)1.98374277
109Sclerocornea (HP:0000647)1.97624461
110Vertebral compression fractures (HP:0002953)1.95702187
111Aplasia/hypoplasia of the uterus (HP:0008684)1.94079519
112Xanthomatosis (HP:0000991)1.93317002
113Testicular atrophy (HP:0000029)1.90206320
114Abolished electroretinogram (ERG) (HP:0000550)1.90179349
115Abnormality of methionine metabolism (HP:0010901)1.89683210
116Pendular nystagmus (HP:0012043)1.89521153
117Hyperbilirubinemia (HP:0002904)1.88967961
118Exercise intolerance (HP:0003546)1.87069080
119Congenital primary aphakia (HP:0007707)1.86604235
120Microvesicular hepatic steatosis (HP:0001414)1.86476198
121Abnormal pancreas size (HP:0012094)1.85791416
122Protrusio acetabuli (HP:0003179)1.85661995
123Abnormality of the labia minora (HP:0012880)1.84995764
124Trismus (HP:0000211)1.84654745
125Colon cancer (HP:0003003)1.83247321
126Abnormality of renal resorption (HP:0011038)1.83044790
127Hyperinsulinemic hypoglycemia (HP:0000825)1.82677574
128Abnormality of the renal cortex (HP:0011035)1.81902349
129Proximal tubulopathy (HP:0000114)1.79291746
130Rough bone trabeculation (HP:0100670)1.79180310
131Abnormality of aspartate family amino acid metabolism (HP:0010899)1.78368503
1323-Methylglutaconic aciduria (HP:0003535)1.78215799
133Brushfield spots (HP:0001088)1.77459124
134Hyperglycinuria (HP:0003108)1.77425782
135Gait imbalance (HP:0002141)1.77206340
136Pancytopenia (HP:0001876)1.77163460
137Absent thumb (HP:0009777)1.76986502
138Renal cortical cysts (HP:0000803)1.76459506
139Abnormality of endocrine pancreas physiology (HP:0012093)1.75770885
140Large for gestational age (HP:0001520)1.72958745
141Blindness (HP:0000618)1.72946223
142Respiratory difficulties (HP:0002880)1.71952566
143X-linked dominant inheritance (HP:0001423)1.69778377
144Emotional lability (HP:0000712)1.68821823
145Adrenal hypoplasia (HP:0000835)1.67268456
146Retinal dysplasia (HP:0007973)1.66672163
147Nephrogenic diabetes insipidus (HP:0009806)1.66296920
148Progressive microcephaly (HP:0000253)1.66237592
149Severe muscular hypotonia (HP:0006829)1.66126265

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.37509940
2NME23.93772748
3STK163.79907573
4VRK23.31616600
5PASK3.05333534
6EIF2AK32.89190802
7MAP4K22.79955723
8BUB12.70208943
9ERN12.66419607
10FLT32.17013407
11ADRBK22.16242298
12VRK12.10260077
13PIM22.06435238
14PDK22.04312745
15NUAK11.99640048
16BRSK21.89524622
17TGFBR11.89417403
18EIF2AK11.89373319
19WEE11.89070196
20PBK1.67223971
21CSNK1G31.62809828
22KDR1.60733839
23PIK3CG1.59529365
24SRPK11.58908700
25CDK81.58228602
26TLK11.56083851
27IRAK31.50375643
28MAPK151.44976279
29CSNK1G11.42795896
30RPS6KB21.40535320
31IRAK41.38805444
32NEK11.36800509
33PINK11.36595338
34SCYL21.34558013
35TAOK31.33993238
36TESK21.31633999
37RPS6KA41.29422888
38TESK11.26426460
39PAK41.21579791
40CSNK1A1L1.21513664
41NME11.20586869
42CSNK1G21.19409492
43EPHA21.19006558
44ABL21.17917248
45MAP3K31.13491622
46DYRK31.09289931
47ACVR1B1.03783376
48MAP3K121.02880795
49INSRR1.02457983
50MAP3K111.01625100
51IRAK11.00652488
52MYLK1.00172230
53LRRK21.00147861
54MST40.99008884
55MAP2K20.98394679
56PLK30.96919908
57CDK70.96241734
58NLK0.96122046
59DAPK10.95400114
60MAP2K70.94789561
61CDK190.94410743
62TRIM280.94289555
63TEC0.93185596
64BMPR1B0.92025975
65OXSR10.90377977
66MAPKAPK30.89724121
67PLK40.89391164
68BTK0.88381958
69PHKG20.88370384
70PHKG10.88370384
71AURKB0.86435124
72MAP2K30.85217038
73PIK3CA0.81180008
74TBK10.80027154
75MST1R0.79960576
76ZAP700.78525706
77IRAK20.77332819
78CHEK20.77009897
79TYK20.76413705
80LIMK10.73305369
81SIK10.73293495
82EPHB20.72297438
83BRAF0.72214680
84CSNK2A10.71707609
85STK390.71054633
86DYRK20.70689259
87MET0.70604443
88AURKA0.68908239
89NEK90.67782811
90PLK20.67037685
91PRKG20.66734286
92MAPKAPK50.66465902
93PRKCG0.65605388
94PAK30.65123294
95PLK10.64700312
96CSNK1A10.64178480
97DYRK1B0.63642821
98TXK0.63597278
99TSSK60.61771711
100KIT0.61489373
101ILK0.61108020
102PRKCI0.60042485
103ZAK0.59068859
104MAP2K60.58989412
105MKNK10.57630750
106CSNK2A20.57252435
107ARAF0.56421353
108TTK0.56009509
109YES10.55765904
110WNK30.55663624
111TAOK20.54528212
112IKBKB0.54340427
113ADRBK10.53748942
114RPS6KA50.51350031
115BRSK10.51136245
116DAPK30.51109295
117PRKCE0.50011164
118CDC70.48150837
119BLK0.46653762
120CAMK2D0.46201079
121ATR0.46119535
122MAP3K80.45718639
123EIF2AK20.43369543
124PTK60.42617968
125MKNK20.41592094
126ATM0.40264006
127ERBB30.39587249
128WNK40.38401836
129CSNK1E0.38153691
130FRK0.37149516
131PAK20.36582568
132MUSK0.36105314
133PAK10.35985082
134PIM10.35953116
135TGFBR20.35273102
136LYN0.34986172
137JAK30.34234286
138PRKACA0.34169510
139CAMK2G0.33548959
140TNIK0.33443754
141AKT20.33332102
142FER0.33289264
143TIE10.32420913
144MAP3K40.32278334
145GRK10.30986345

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030104.16247550
2Protein export_Homo sapiens_hsa030604.09767946
3Proteasome_Homo sapiens_hsa030502.88532071
4Maturity onset diabetes of the young_Homo sapiens_hsa049502.58921506
5Folate biosynthesis_Homo sapiens_hsa007902.37526972
6DNA replication_Homo sapiens_hsa030302.12076057
7Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.07792539
8Ascorbate and aldarate metabolism_Homo sapiens_hsa000532.06676428
9RNA polymerase_Homo sapiens_hsa030201.95245960
10Sulfur metabolism_Homo sapiens_hsa009201.90909627
11Drug metabolism - other enzymes_Homo sapiens_hsa009831.85710805
12Pentose and glucuronate interconversions_Homo sapiens_hsa000401.84457678
13Primary bile acid biosynthesis_Homo sapiens_hsa001201.83277019
14Pyrimidine metabolism_Homo sapiens_hsa002401.82045800
15Oxidative phosphorylation_Homo sapiens_hsa001901.80439318
16Mismatch repair_Homo sapiens_hsa034301.73398806
17One carbon pool by folate_Homo sapiens_hsa006701.73337802
18Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.66303934
19Parkinsons disease_Homo sapiens_hsa050121.52768424
20Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.48431588
21Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.47759788
22Selenocompound metabolism_Homo sapiens_hsa004501.47257932
23Chemical carcinogenesis_Homo sapiens_hsa052041.45349563
24Spliceosome_Homo sapiens_hsa030401.45111065
25Base excision repair_Homo sapiens_hsa034101.43563556
26Glutathione metabolism_Homo sapiens_hsa004801.39847831
27Sulfur relay system_Homo sapiens_hsa041221.39786318
28Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.38327291
29Peroxisome_Homo sapiens_hsa041461.38125143
30Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.37937544
31Protein processing in endoplasmic reticulum_Homo sapiens_hsa041411.34994150
32Homologous recombination_Homo sapiens_hsa034401.33244416
33Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.30949192
34Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.30715658
35Fanconi anemia pathway_Homo sapiens_hsa034601.27207816
36Tryptophan metabolism_Homo sapiens_hsa003801.25116388
37Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.24686480
38Nucleotide excision repair_Homo sapiens_hsa034201.24118642
39N-Glycan biosynthesis_Homo sapiens_hsa005101.22811324
40Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.15207112
41Cyanoamino acid metabolism_Homo sapiens_hsa004601.14484283
42Fatty acid degradation_Homo sapiens_hsa000711.14141140
43Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.13627771
44Cardiac muscle contraction_Homo sapiens_hsa042601.11080432
45Fat digestion and absorption_Homo sapiens_hsa049751.09413076
46Histidine metabolism_Homo sapiens_hsa003401.09191737
47Nitrogen metabolism_Homo sapiens_hsa009101.08929715
48Cysteine and methionine metabolism_Homo sapiens_hsa002701.08257808
49Complement and coagulation cascades_Homo sapiens_hsa046101.06870980
50Huntingtons disease_Homo sapiens_hsa050161.04661391
51Steroid hormone biosynthesis_Homo sapiens_hsa001401.04484230
52Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.03916483
53Other glycan degradation_Homo sapiens_hsa005111.03469211
54Retinol metabolism_Homo sapiens_hsa008301.01039460
55Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.00048862
56Phototransduction_Homo sapiens_hsa047440.97638117
57Caffeine metabolism_Homo sapiens_hsa002320.96499971
58Galactose metabolism_Homo sapiens_hsa000520.95970357
59Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030080.95111300
60Phenylalanine metabolism_Homo sapiens_hsa003600.95082950
61Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.94494965
62Arginine and proline metabolism_Homo sapiens_hsa003300.94343431
63Alzheimers disease_Homo sapiens_hsa050100.92135054
64alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.91727887
65Tyrosine metabolism_Homo sapiens_hsa003500.91688885
66Propanoate metabolism_Homo sapiens_hsa006400.90572647
67Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.86462198
68Biosynthesis of amino acids_Homo sapiens_hsa012300.83456314
69Fatty acid elongation_Homo sapiens_hsa000620.83446459
70beta-Alanine metabolism_Homo sapiens_hsa004100.83424467
71Pyruvate metabolism_Homo sapiens_hsa006200.83132804
72Starch and sucrose metabolism_Homo sapiens_hsa005000.82792705
73Steroid biosynthesis_Homo sapiens_hsa001000.82268181
74Metabolic pathways_Homo sapiens_hsa011000.78440625
75RNA transport_Homo sapiens_hsa030130.78380669
76Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.78312072
77Vitamin B6 metabolism_Homo sapiens_hsa007500.78168817
78Non-homologous end-joining_Homo sapiens_hsa034500.74585821
79Ether lipid metabolism_Homo sapiens_hsa005650.74143112
80Carbon metabolism_Homo sapiens_hsa012000.72881900
81Purine metabolism_Homo sapiens_hsa002300.70585639
82Arachidonic acid metabolism_Homo sapiens_hsa005900.69559739
832-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.69196534
84Pentose phosphate pathway_Homo sapiens_hsa000300.67143565
85Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.65765868
86Collecting duct acid secretion_Homo sapiens_hsa049660.65231242
87Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.64547661
88Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.63019424
89Butanoate metabolism_Homo sapiens_hsa006500.62779391
90RNA degradation_Homo sapiens_hsa030180.61015580
91SNARE interactions in vesicular transport_Homo sapiens_hsa041300.60263924
92Legionellosis_Homo sapiens_hsa051340.58837341
93Arginine biosynthesis_Homo sapiens_hsa002200.57129588
94Protein digestion and absorption_Homo sapiens_hsa049740.56153351
95Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.54908680
96Vibrio cholerae infection_Homo sapiens_hsa051100.53323159
97Glycosaminoglycan degradation_Homo sapiens_hsa005310.52619076
98Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.51861975
99Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.50957527
100Fatty acid metabolism_Homo sapiens_hsa012120.50498744
101Basal transcription factors_Homo sapiens_hsa030220.50017576
102Regulation of autophagy_Homo sapiens_hsa041400.48227176
103Staphylococcus aureus infection_Homo sapiens_hsa051500.47085885
104Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.46800879
105Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.45707416
106Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.45591862
107Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.41589485
108Vitamin digestion and absorption_Homo sapiens_hsa049770.40244854
109Linoleic acid metabolism_Homo sapiens_hsa005910.39880674
110Fructose and mannose metabolism_Homo sapiens_hsa000510.39079291
111Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.38241458
112Systemic lupus erythematosus_Homo sapiens_hsa053220.37766673
113PPAR signaling pathway_Homo sapiens_hsa033200.36740139
114Cell cycle_Homo sapiens_hsa041100.35737566
115Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.33765233
116Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.33615780
117Mineral absorption_Homo sapiens_hsa049780.31607094

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