CNTN6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is a member of the immunoglobulin superfamily. It is a glycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein that functions as a cell adhesion molecule. It may play a role in the formation of axon connections in the developing nervous system. Alternative splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1neuron cell-cell adhesion (GO:0007158)6.05601520
2vocalization behavior (GO:0071625)6.00795657
3regulation of short-term neuronal synaptic plasticity (GO:0048172)5.44476326
4regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.42525062
5locomotory exploration behavior (GO:0035641)5.39740244
6synaptic vesicle exocytosis (GO:0016079)5.36096843
7positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.30012274
8neurotransmitter-gated ion channel clustering (GO:0072578)5.09010169
9regulation of glutamate receptor signaling pathway (GO:1900449)5.04561563
10regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)4.94601740
11cerebellar granule cell differentiation (GO:0021707)4.78974995
12neuronal action potential propagation (GO:0019227)4.76955722
13regulation of synaptic vesicle exocytosis (GO:2000300)4.74284288
14neurotransmitter secretion (GO:0007269)4.68436381
15protein localization to synapse (GO:0035418)4.66147606
16positive regulation of calcium ion-dependent exocytosis (GO:0045956)4.65161212
17glutamate secretion (GO:0014047)4.64606591
18ionotropic glutamate receptor signaling pathway (GO:0035235)4.61998461
19presynaptic membrane assembly (GO:0097105)4.61624233
20synaptic vesicle docking involved in exocytosis (GO:0016081)4.59367279
21postsynaptic membrane organization (GO:0001941)4.56173964
22synaptic vesicle maturation (GO:0016188)4.51932078
23glutamate receptor signaling pathway (GO:0007215)4.48550897
24exploration behavior (GO:0035640)4.40344755
25synaptic transmission, glutamatergic (GO:0035249)4.33449551
26gamma-aminobutyric acid transport (GO:0015812)4.32485925
27neuron-neuron synaptic transmission (GO:0007270)4.31233300
28presynaptic membrane organization (GO:0097090)4.25771967
29pyrimidine nucleobase catabolic process (GO:0006208)4.24514566
30gamma-aminobutyric acid signaling pathway (GO:0007214)4.22054268
31regulation of synaptic vesicle transport (GO:1902803)4.09034242
32regulation of inhibitory postsynaptic membrane potential (GO:0060080)4.08766403
33G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.99566207
34membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.98522525
35positive regulation of synapse maturation (GO:0090129)3.90894579
36long-term synaptic potentiation (GO:0060291)3.89130066
37cerebellar Purkinje cell differentiation (GO:0021702)3.87827210
38regulation of synaptic transmission, glutamatergic (GO:0051966)3.87182092
39negative regulation of synaptic transmission, GABAergic (GO:0032229)3.86193434
40regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.76836801
41negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.74382768
42positive regulation of synapse assembly (GO:0051965)3.74279492
43neurotransmitter transport (GO:0006836)3.73625699
44layer formation in cerebral cortex (GO:0021819)3.72460900
45positive regulation of membrane potential (GO:0045838)3.72316618
46retinal ganglion cell axon guidance (GO:0031290)3.71385341
47neuron recognition (GO:0008038)3.68132019
48transmission of nerve impulse (GO:0019226)3.65146567
49short-term memory (GO:0007614)3.64321938
50long-term memory (GO:0007616)3.60858647
51regulation of excitatory postsynaptic membrane potential (GO:0060079)3.59382732
52response to histamine (GO:0034776)3.58079926
53positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.54778455
54positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.54513558
55regulation of long-term neuronal synaptic plasticity (GO:0048169)3.51188536
56regulation of postsynaptic membrane potential (GO:0060078)3.48452327
57regulation of neurotransmitter levels (GO:0001505)3.46601158
58gonadal mesoderm development (GO:0007506)3.45949010
59neuronal stem cell maintenance (GO:0097150)3.45240560
60neuromuscular process controlling posture (GO:0050884)3.44856425
61startle response (GO:0001964)3.43974153
62proline transport (GO:0015824)3.43401183
63regulation of synapse structural plasticity (GO:0051823)3.42205534
64positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.39065666
65behavioral response to nicotine (GO:0035095)3.38578599
66regulation of neuronal synaptic plasticity (GO:0048168)3.35242233
67serotonin metabolic process (GO:0042428)3.34656793
68synapse assembly (GO:0007416)3.32156807
69cell differentiation in hindbrain (GO:0021533)3.32098945
70axonal fasciculation (GO:0007413)3.31726286
71regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.31304693
72mechanosensory behavior (GO:0007638)3.30683218
73nucleobase catabolic process (GO:0046113)3.29794186
74regulation of neurotransmitter secretion (GO:0046928)3.29376771
75membrane hyperpolarization (GO:0060081)3.28306988
76regulation of synapse maturation (GO:0090128)3.26940946
77spinal cord association neuron differentiation (GO:0021527)3.24963867
78neurofilament cytoskeleton organization (GO:0060052)3.23931098
79epithelial cilium movement (GO:0003351)3.23927905
80dendritic spine morphogenesis (GO:0060997)3.22180384
81regulation of female receptivity (GO:0045924)3.18914506
82response to pheromone (GO:0019236)3.18808670
83regulation of synaptic plasticity (GO:0048167)3.17859915
84positive regulation of synaptic transmission (GO:0050806)3.15936689
85paraxial mesoderm development (GO:0048339)3.15513070
86ATP hydrolysis coupled proton transport (GO:0015991)3.15283437
87energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988)3.15283437
88auditory behavior (GO:0031223)3.14966210
89activation of protein kinase A activity (GO:0034199)3.14857387
90adult walking behavior (GO:0007628)3.13221776
91female mating behavior (GO:0060180)3.12059273
92membrane depolarization (GO:0051899)3.10462125
93regulation of neurotransmitter transport (GO:0051588)3.09692977
94transferrin transport (GO:0033572)3.09292363
95membrane depolarization during action potential (GO:0086010)3.08750157
96synaptic vesicle endocytosis (GO:0048488)3.08371513
97negative regulation of cytosolic calcium ion concentration (GO:0051481)3.07867191
98positive regulation of gastrulation (GO:2000543)3.07593212
99cellular potassium ion homeostasis (GO:0030007)3.07538012
100somite development (GO:0061053)3.04691977
101microtubule depolymerization (GO:0007019)3.04424301
102synaptic transmission (GO:0007268)3.02948965
103learning (GO:0007612)3.02502210
104positive regulation of synaptic transmission, GABAergic (GO:0032230)3.01951959
105behavioral response to cocaine (GO:0048148)3.01008110
106regulation of glutamate secretion (GO:0014048)3.00143792
107regulation of synaptic transmission (GO:0050804)2.98170412
108intraspecies interaction between organisms (GO:0051703)2.98071918
109social behavior (GO:0035176)2.98071918
110synapse organization (GO:0050808)2.97806194
111regulation of synapse assembly (GO:0051963)2.97772657
112striatum development (GO:0021756)2.96666878
113retinal cone cell development (GO:0046549)2.96220087
114regulation of synaptic transmission, GABAergic (GO:0032228)2.95653566
115regulation of respiratory system process (GO:0044065)2.95226286
116positive regulation of neurotransmitter transport (GO:0051590)2.94843189
117retina layer formation (GO:0010842)2.91855144
118behavioral fear response (GO:0001662)2.91791591
119behavioral defense response (GO:0002209)2.91791591
120thalamus development (GO:0021794)2.91230758
121sequestering of actin monomers (GO:0042989)2.83605888
122positive regulation of phosphoprotein phosphatase activity (GO:0032516)2.83572470
123central nervous system projection neuron axonogenesis (GO:0021952)2.82643540
124primary amino compound metabolic process (GO:1901160)2.81898477
125dopamine biosynthetic process (GO:0042416)2.80216298
126substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.79901896
127substrate-independent telencephalic tangential migration (GO:0021826)2.79901896
128cilium movement (GO:0003341)2.78751273
129epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)2.78508774
130limb bud formation (GO:0060174)2.76339939
131regulation of timing of cell differentiation (GO:0048505)2.68221264
132somite rostral/caudal axis specification (GO:0032525)2.67892887
133behavioral response to ethanol (GO:0048149)2.65669677
134suckling behavior (GO:0001967)2.64624480
135regulation of development, heterochronic (GO:0040034)2.60577522
136sodium ion export (GO:0071436)2.59708108
137nonmotile primary cilium assembly (GO:0035058)2.57843516
138response to auditory stimulus (GO:0010996)2.54538932
139inner ear receptor stereocilium organization (GO:0060122)2.54024686
140left/right axis specification (GO:0070986)2.51392245
141neuron fate determination (GO:0048664)2.51220007
142positive regulation of dendritic spine morphogenesis (GO:0061003)2.50617459
143prepulse inhibition (GO:0060134)2.50581547
144neuron migration (GO:0001764)2.50430020
145adult behavior (GO:0030534)2.48917512
146adult feeding behavior (GO:0008343)2.48529895
147central nervous system neuron development (GO:0021954)2.47370320
148cellular sodium ion homeostasis (GO:0006883)2.46019123
149positive regulation of action potential (GO:0045760)2.45978177
150cochlea development (GO:0090102)2.45941203

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.63481109
2GBX2_23144817_ChIP-Seq_PC3_Human4.31497904
3SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.99343190
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.94838093
5JARID2_20064375_ChIP-Seq_MESCs_Mouse2.93998788
6REST_21632747_ChIP-Seq_MESCs_Mouse2.63786892
7GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.54772435
8TAF15_26573619_Chip-Seq_HEK293_Human2.53692322
9SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.52442313
10EZH2_27304074_Chip-Seq_ESCs_Mouse2.51936084
11EZH2_18974828_ChIP-Seq_MESCs_Mouse2.49663782
12RNF2_18974828_ChIP-Seq_MESCs_Mouse2.49663782
13HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse2.47727366
14JARID2_20075857_ChIP-Seq_MESCs_Mouse2.40683797
15SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.37812451
16SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.33078990
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.31316054
18* CTBP2_25329375_ChIP-Seq_LNCAP_Human2.31210635
19SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.29868362
20NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.28200741
21AR_21572438_ChIP-Seq_LNCaP_Human2.27689618
22EED_16625203_ChIP-ChIP_MESCs_Mouse2.24337351
23RBPJ_22232070_ChIP-Seq_NCS_Mouse2.18979046
24* REST_18959480_ChIP-ChIP_MESCs_Mouse2.15824692
25ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.11995382
26CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons2.07020801
27ZFP57_27257070_Chip-Seq_ESCs_Mouse2.05993803
28EZH2_27294783_Chip-Seq_ESCs_Mouse2.05585152
29RNF2_27304074_Chip-Seq_ESCs_Mouse2.01958524
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.97852014
31CTBP1_25329375_ChIP-Seq_LNCAP_Human1.95011838
32DROSHA_22980978_ChIP-Seq_HELA_Human1.94455054
33* SMAD4_21799915_ChIP-Seq_A2780_Human1.93407942
34* RARB_27405468_Chip-Seq_BRAIN_Mouse1.91419079
35IKZF1_21737484_ChIP-ChIP_HCT116_Human1.90597972
36GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.84544927
37TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.82376055
38* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.77622926
39PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.70504416
40P300_19829295_ChIP-Seq_ESCs_Human1.69398204
41* CBX2_27304074_Chip-Seq_ESCs_Mouse1.63442628
42POU3F2_20337985_ChIP-ChIP_501MEL_Human1.60916032
43EWS_26573619_Chip-Seq_HEK293_Human1.60238585
44BMI1_23680149_ChIP-Seq_NPCS_Mouse1.60154615
45ZNF274_21170338_ChIP-Seq_K562_Hela1.60033369
46PIAS1_25552417_ChIP-Seq_VCAP_Human1.49874444
47MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.49120922
48RNF2_27304074_Chip-Seq_NSC_Mouse1.48049281
49SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.47851111
50TOP2B_26459242_ChIP-Seq_MCF-7_Human1.45970782
51* SOX2_21211035_ChIP-Seq_LN229_Gbm1.44493664
52MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.44140988
53* AR_25329375_ChIP-Seq_VCAP_Human1.43973655
54SMAD3_21741376_ChIP-Seq_EPCs_Human1.41606893
55IGF1R_20145208_ChIP-Seq_DFB_Human1.41258298
56FUS_26573619_Chip-Seq_HEK293_Human1.39440321
57* STAT3_23295773_ChIP-Seq_U87_Human1.39268666
58SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.37103503
59* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.36791847
60PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.31846596
61RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.30913426
62CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.30314358
63ERG_21242973_ChIP-ChIP_JURKAT_Human1.29564858
64POU5F1_16153702_ChIP-ChIP_HESCs_Human1.28228094
65* ER_23166858_ChIP-Seq_MCF-7_Human1.24005712
66AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.23611624
67* TCF4_23295773_ChIP-Seq_U87_Human1.23525514
68CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.23400514
69NR3C1_23031785_ChIP-Seq_PC12_Mouse1.21962057
70TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.21810535
71KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.20662386
72EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.18561224
73STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16329987
74AR_19668381_ChIP-Seq_PC3_Human1.16328170
75BCAT_22108803_ChIP-Seq_LS180_Human1.15761075
76MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse1.15402776
77RUNX2_22187159_ChIP-Seq_PCA_Human1.15293625
78UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.14318507
79SMAD_19615063_ChIP-ChIP_OVARY_Human1.13466867
80ARNT_22903824_ChIP-Seq_MCF-7_Human1.12877211
81RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.08782324
82RING1B_27294783_Chip-Seq_ESCs_Mouse1.07839529
83* YAP1_20516196_ChIP-Seq_MESCs_Mouse1.06533296
84TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.05914952
85AHR_22903824_ChIP-Seq_MCF-7_Human1.05673452
86POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.05597875
87TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.05597875
88JUN_21703547_ChIP-Seq_K562_Human1.04795247
89ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.03679621
90* TAL1_26923725_Chip-Seq_HPCs_Mouse1.03434167
91P53_22127205_ChIP-Seq_FIBROBLAST_Human1.02160225
92VDR_22108803_ChIP-Seq_LS180_Human1.01053475
93LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.00666318
94NANOG_18555785_Chip-Seq_ESCs_Mouse1.00380111
95TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.99689020
96CEBPB_26923725_Chip-Seq_MESODERM_Mouse0.98850009
97TP53_18474530_ChIP-ChIP_U2OS_Human0.98350448
98KLF5_20875108_ChIP-Seq_MESCs_Mouse0.98308584
99SMAD3_21741376_ChIP-Seq_ESCs_Human0.98199649
100LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.98108614
101CBP_20019798_ChIP-Seq_JUKART_Human0.97731355
102IRF4_20064451_ChIP-Seq_CD4+T_Mouse0.97731355
103PRDM14_20953172_ChIP-Seq_ESCs_Human0.97005026
104TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.96726203
105EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse0.96169043
106TP53_20018659_ChIP-ChIP_R1E_Mouse0.95596469
107CDX2_19796622_ChIP-Seq_MESCs_Mouse0.95180731
108RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.94518266
109CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.94274231
110NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93336470
111KDM2B_26808549_Chip-Seq_REH_Human0.93265332
112PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.93153268
113FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse0.92581769
114ZNF217_24962896_ChIP-Seq_MCF-7_Human0.92136938
115DNAJC2_21179169_ChIP-ChIP_NT2_Human0.90065860
116* MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.89897746
117TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.88398449
118SOX9_26525672_Chip-Seq_HEART_Mouse0.88195871
119RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.87612543
120FLI1_27457419_Chip-Seq_LIVER_Mouse0.87580322

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity5.04557315
2MP0003880_abnormal_central_pattern4.44204589
3MP0003635_abnormal_synaptic_transmissio3.98667734
4MP0009046_muscle_twitch3.82951791
5MP0009745_abnormal_behavioral_response3.43150784
6MP0001968_abnormal_touch/_nociception3.27365656
7MP0002064_seizures3.25157722
8MP0002063_abnormal_learning/memory/cond3.17649114
9MP0004270_analgesia3.16648942
10MP0002572_abnormal_emotion/affect_behav2.91965461
11MP0002736_abnormal_nociception_after2.88130735
12MP0002272_abnormal_nervous_system2.76301538
13MP0003136_yellow_coat_color2.73042959
14MP0002734_abnormal_mechanical_nocicepti2.70447398
15MP0005423_abnormal_somatic_nervous2.65333191
16MP0001486_abnormal_startle_reflex2.50367664
17MP0001501_abnormal_sleep_pattern2.40525764
18MP0001440_abnormal_grooming_behavior2.39364924
19MP0003122_maternal_imprinting2.36924003
20MP0002735_abnormal_chemical_nociception2.33347243
21MP0002067_abnormal_sensory_capabilities2.31925626
22MP0003787_abnormal_imprinting2.15157045
23MP0005645_abnormal_hypothalamus_physiol2.09640042
24MP0000566_synostosis2.07319868
25MP0003890_abnormal_embryonic-extraembry2.05859962
26MP0002184_abnormal_innervation2.02054447
27MP0006292_abnormal_olfactory_placode2.01590165
28MP0004142_abnormal_muscle_tone2.00871996
29MP0005646_abnormal_pituitary_gland1.98429837
30MP0001984_abnormal_olfaction1.97098104
31MP0008569_lethality_at_weaning1.96364373
32MP0002733_abnormal_thermal_nociception1.96036035
33MP0009780_abnormal_chondrocyte_physiolo1.94719272
34MP0001970_abnormal_pain_threshold1.94711448
35MP0001529_abnormal_vocalization1.93821645
36MP0006276_abnormal_autonomic_nervous1.93315704
37MP0002822_catalepsy1.91875933
38MP0002557_abnormal_social/conspecific_i1.91339844
39MP0005386_behavior/neurological_phenoty1.87568636
40MP0004924_abnormal_behavior1.87568636
41MP0002938_white_spotting1.83310780
42MP0000778_abnormal_nervous_system1.75473370
43MP0003879_abnormal_hair_cell1.63134743
44MP0009379_abnormal_foot_pigmentation1.56417178
45MP0003329_amyloid_beta_deposits1.48378663
46MP0000955_abnormal_spinal_cord1.47857049
47MP0004811_abnormal_neuron_physiology1.47323687
48* MP0002066_abnormal_motor_capabilities/c1.46925611
49MP0004145_abnormal_muscle_electrophysio1.42279398
50MP0002234_abnormal_pharynx_morphology1.36826926
51MP0001502_abnormal_circadian_rhythm1.36557041
52MP0002837_dystrophic_cardiac_calcinosis1.36036646
53* MP0002882_abnormal_neuron_morphology1.34417689
54MP0008789_abnormal_olfactory_epithelium1.33965194
55MP0002751_abnormal_autonomic_nervous1.32508704
56MP0004742_abnormal_vestibular_system1.29714572
57MP0004133_heterotaxia1.28666298
58MP0001188_hyperpigmentation1.24524535
59MP0001485_abnormal_pinna_reflex1.23277894
60MP0004858_abnormal_nervous_system1.21651502
61MP0005253_abnormal_eye_physiology1.20781461
62MP0003119_abnormal_digestive_system1.18463684
63MP0000049_abnormal_middle_ear1.16091659
64MP0001986_abnormal_taste_sensitivity1.14851779
65MP0001293_anophthalmia1.13378918
66MP0000751_myopathy1.10534110
67MP0008877_abnormal_DNA_methylation1.10385850
68* MP0002152_abnormal_brain_morphology1.09583859
69MP0010030_abnormal_orbit_morphology1.08794509
70MP0003938_abnormal_ear_development1.08003153
71MP0002909_abnormal_adrenal_gland1.06599320
72MP0004885_abnormal_endolymph1.06035038
73MP0003121_genomic_imprinting1.05774982
74MP0001905_abnormal_dopamine_level1.03918397
75MP0005551_abnormal_eye_electrophysiolog1.00790843
76MP0003385_abnormal_body_wall1.00256419
77MP0003633_abnormal_nervous_system0.99804408
78MP0002233_abnormal_nose_morphology0.98235462
79MP0000631_abnormal_neuroendocrine_gland0.97451532
80MP0003631_nervous_system_phenotype0.96831522
81MP0002095_abnormal_skin_pigmentation0.96594779
82MP0002876_abnormal_thyroid_physiology0.95918947
83MP0000013_abnormal_adipose_tissue0.94094838
84MP0001286_abnormal_eye_development0.93994548
85MP0003183_abnormal_peptide_metabolism0.93626272
86MP0005377_hearing/vestibular/ear_phenot0.93566229
87MP0003878_abnormal_ear_physiology0.93566229
88MP0010386_abnormal_urinary_bladder0.92436109
89MP0002229_neurodegeneration0.92251341
90MP0005248_abnormal_Harderian_gland0.92035579
91MP0001963_abnormal_hearing_physiology0.91536266
92MP0002069_abnormal_eating/drinking_beha0.91269383
93MP0008872_abnormal_physiological_respon0.90236863
94MP0004147_increased_porphyrin_level0.89343682
95MP0004215_abnormal_myocardial_fiber0.89201647
96MP0003123_paternal_imprinting0.87789208
97MP0000534_abnormal_ureter_morphology0.87624176
98MP0003632_abnormal_nervous_system0.87374864
99MP0003283_abnormal_digestive_organ0.85957774
100MP0003646_muscle_fatigue0.85719131
101MP0004085_abnormal_heartbeat0.84025900
102MP0003937_abnormal_limbs/digits/tail_de0.80938814
103MP0003942_abnormal_urinary_system0.80622407
104MP0005394_taste/olfaction_phenotype0.80029235
105MP0005499_abnormal_olfactory_system0.80029235
106MP0002752_abnormal_somatic_nervous0.79991826
107MP0005391_vision/eye_phenotype0.77458105
108MP0002928_abnormal_bile_duct0.76648623
109MP0005195_abnormal_posterior_eye0.76557742
110MP0002102_abnormal_ear_morphology0.75268846
111MP0005171_absent_coat_pigmentation0.72713287
112MP0003634_abnormal_glial_cell0.71969824
113MP0008874_decreased_physiological_sensi0.69478854
114MP0001177_atelectasis0.68980792
115MP0005535_abnormal_body_temperature0.65309025
116MP0000026_abnormal_inner_ear0.64093778
117MP0002638_abnormal_pupillary_reflex0.63746128
118MP0003137_abnormal_impulse_conducting0.62608960
119MP0001943_abnormal_respiration0.61522433
120MP0001664_abnormal_digestion0.61388051
121MP0004484_altered_response_of0.60690901
122MP0002332_abnormal_exercise_endurance0.58062745
123MP0004233_abnormal_muscle_weight0.57530733
124MP0010770_preweaning_lethality0.56758872
125MP0002082_postnatal_lethality0.56758872
126MP0002653_abnormal_ependyma_morphology0.56068618
127MP0000604_amyloidosis0.55927160
128MP0001299_abnormal_eye_distance/0.55910977
129MP0010769_abnormal_survival0.54721505
130MP0000569_abnormal_digit_pigmentation0.53883416
131MP0006072_abnormal_retinal_apoptosis0.53689358
132MP0003861_abnormal_nervous_system0.52080629
133MP0010768_mortality/aging0.51409157

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)8.01581695
2Atonic seizures (HP:0010819)5.98653715
3Focal seizures (HP:0007359)5.68350990
4Febrile seizures (HP:0002373)5.23666082
5Myokymia (HP:0002411)5.15533027
6Epileptic encephalopathy (HP:0200134)5.12974108
7Progressive cerebellar ataxia (HP:0002073)4.74233087
8Visual hallucinations (HP:0002367)4.67291670
9Absence seizures (HP:0002121)4.58772345
10Hyperventilation (HP:0002883)4.33179223
11Dialeptic seizures (HP:0011146)4.16466787
12Broad-based gait (HP:0002136)3.83176467
13Generalized tonic-clonic seizures (HP:0002069)3.80681423
14Gaze-evoked nystagmus (HP:0000640)3.72033977
15Polyphagia (HP:0002591)3.60650861
16Abnormality of binocular vision (HP:0011514)3.46304523
17Diplopia (HP:0000651)3.46304523
18Abnormal eating behavior (HP:0100738)3.38368509
19Ulnar claw (HP:0001178)3.35112183
20Action tremor (HP:0002345)3.28827393
21Dysdiadochokinesis (HP:0002075)3.14121400
22Progressive inability to walk (HP:0002505)3.12341370
23Gait imbalance (HP:0002141)3.06383326
24Truncal ataxia (HP:0002078)3.03399279
25Poor eye contact (HP:0000817)3.00780825
26Impaired vibration sensation in the lower limbs (HP:0002166)3.00126590
27Fetal akinesia sequence (HP:0001989)2.96961206
28Abnormal hair whorl (HP:0010721)2.88766959
29Scanning speech (HP:0002168)2.87943285
30Impaired social interactions (HP:0000735)2.83913122
31Abnormal social behavior (HP:0012433)2.83913122
32Failure to thrive in infancy (HP:0001531)2.80220323
33Congenital sensorineural hearing impairment (HP:0008527)2.78676602
34Impaired smooth pursuit (HP:0007772)2.76443344
35Dysmetric saccades (HP:0000641)2.76404241
36Excessive salivation (HP:0003781)2.76080767
37Drooling (HP:0002307)2.76080767
38Dysmetria (HP:0001310)2.69242426
39Genetic anticipation (HP:0003743)2.68426863
40Epileptiform EEG discharges (HP:0011182)2.67871404
41Mutism (HP:0002300)2.67796066
42Pheochromocytoma (HP:0002666)2.67505626
43Poor suck (HP:0002033)2.66999693
44Anxiety (HP:0000739)2.65431420
45Hemiparesis (HP:0001269)2.63698944
46Ankle clonus (HP:0011448)2.62592357
47Congenital primary aphakia (HP:0007707)2.60982801
48EEG with generalized epileptiform discharges (HP:0011198)2.57739390
49Abnormality of ocular smooth pursuit (HP:0000617)2.57244065
50Depression (HP:0000716)2.56159420
51Specific learning disability (HP:0001328)2.54145335
52Limb dystonia (HP:0002451)2.53040293
53Amblyopia (HP:0000646)2.52392038
54Absent speech (HP:0001344)2.50210438
55Hypsarrhythmia (HP:0002521)2.47958926
56Pancreatic fibrosis (HP:0100732)2.46551495
57Medial flaring of the eyebrow (HP:0010747)2.46284939
58Pancreatic cysts (HP:0001737)2.46106704
59Abnormality of the labia minora (HP:0012880)2.45588844
60Inability to walk (HP:0002540)2.45256566
61Neuroendocrine neoplasm (HP:0100634)2.43983218
62Status epilepticus (HP:0002133)2.42131519
63Abnormality of the corticospinal tract (HP:0002492)2.40475353
64Nephrogenic diabetes insipidus (HP:0009806)2.37625158
65True hermaphroditism (HP:0010459)2.35790156
66Supranuclear gaze palsy (HP:0000605)2.33764027
67Type II lissencephaly (HP:0007260)2.29460003
68Cutaneous finger syndactyly (HP:0010554)2.28272546
69Hemiplegia (HP:0002301)2.24798849
70Urinary bladder sphincter dysfunction (HP:0002839)2.24201309
71Colon cancer (HP:0003003)2.23682503
72Narrow nasal bridge (HP:0000446)2.22656898
73Anterior segment dysgenesis (HP:0007700)2.21498469
74Akinesia (HP:0002304)2.21464013
75Blue irides (HP:0000635)2.19971903
76Neuronal loss in central nervous system (HP:0002529)2.16529780
77Spastic gait (HP:0002064)2.14930167
78Esotropia (HP:0000565)2.13779206
79Hyperthyroidism (HP:0000836)2.13158940
80Generalized myoclonic seizures (HP:0002123)2.11257835
81Impaired vibratory sensation (HP:0002495)2.10945440
82Renal hypoplasia (HP:0000089)2.08818861
83Abnormality of the lower motor neuron (HP:0002366)2.08184675
84Congenital, generalized hypertrichosis (HP:0004540)2.07969463
85Abnormality of midbrain morphology (HP:0002418)2.07627990
86Molar tooth sign on MRI (HP:0002419)2.07627990
87Agitation (HP:0000713)2.06833566
88Heterochromia iridis (HP:0001100)2.06555492
89Amyotrophic lateral sclerosis (HP:0007354)2.06399836
90Oligomenorrhea (HP:0000876)2.05243724
91Cerebellar dysplasia (HP:0007033)2.05171706
92Protruding tongue (HP:0010808)2.04650958
93Urinary urgency (HP:0000012)2.03528589
94Optic nerve hypoplasia (HP:0000609)2.03196046
95Abnormality of the renal medulla (HP:0100957)2.00805408
96Pendular nystagmus (HP:0012043)1.98996581
97Midline defect of the nose (HP:0004122)1.98350059
98Gait ataxia (HP:0002066)1.97975323
99Genital tract atresia (HP:0001827)1.96513096
100Intention tremor (HP:0002080)1.96216651
101Bradykinesia (HP:0002067)1.94795401
102Nephronophthisis (HP:0000090)1.94553693
103Poor coordination (HP:0002370)1.94452922
104Degeneration of the lateral corticospinal tracts (HP:0002314)1.94247085
105Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.94247085
106Lissencephaly (HP:0001339)1.93750767
107Acute necrotizing encephalopathy (HP:0006965)1.92807893
108Sleep apnea (HP:0010535)1.92044484
109Abnormal mitochondria in muscle tissue (HP:0008316)1.91816281
110Torticollis (HP:0000473)1.91787278
111Generalized hypotonia (HP:0001290)1.91428170
112Psychosis (HP:0000709)1.91421256
113Vaginal atresia (HP:0000148)1.90934017
114Postural tremor (HP:0002174)1.90682195
115Postural instability (HP:0002172)1.88059775
116Rib fusion (HP:0000902)1.87924643
117Septo-optic dysplasia (HP:0100842)1.87250520
118Hypoventilation (HP:0002791)1.86937605
119Incomplete penetrance (HP:0003829)1.86645009
120Aplasia/Hypoplasia of the tibia (HP:0005772)1.86172696
121Abnormality of saccadic eye movements (HP:0000570)1.84400012
122Cutaneous syndactyly (HP:0012725)1.83537388
123Tented upper lip vermilion (HP:0010804)1.83449009
124Severe Myopia (HP:0011003)1.82727967
125Focal dystonia (HP:0004373)1.82350026
126Neoplasm of the peripheral nervous system (HP:0100007)1.81078191
127Stereotypic behavior (HP:0000733)1.81037725
128Anophthalmia (HP:0000528)1.79694229
129Abnormal ciliary motility (HP:0012262)1.79350671
130Hemivertebrae (HP:0002937)1.78720387
131Dynein arm defect of respiratory motile cilia (HP:0012255)1.76853529
132Absent/shortened dynein arms (HP:0200106)1.76853529
133Aqueductal stenosis (HP:0002410)1.75246434
134Hypoplasia of the iris (HP:0007676)1.74658269
135Tracheomalacia (HP:0002779)1.73476595
136Morphological abnormality of the pyramidal tract (HP:0002062)1.70727599
137Prominent supraorbital ridges (HP:0000336)1.70620550
138Postaxial hand polydactyly (HP:0001162)1.69370621
139Decreased circulating renin level (HP:0003351)1.69219139
140Chorioretinal atrophy (HP:0000533)1.68516105
141Abnormal respiratory motile cilium physiology (HP:0012261)1.68189523
142Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.67444365
143Hyperglycinemia (HP:0002154)1.67022405
144Morphological abnormality of the middle ear (HP:0008609)1.60794367
145Anencephaly (HP:0002323)1.60129000
146Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.59638037
147Vitreoretinal degeneration (HP:0000655)1.58725248
148Cystic liver disease (HP:0006706)1.58631373
149Patchy hypopigmentation of hair (HP:0011365)1.58258699
150Amelogenesis imperfecta (HP:0000705)1.57561211
151Decreased number of large peripheral myelinated nerve fibers (HP:0003387)1.57260689
152Aplasia/Hypoplasia of the tongue (HP:0010295)1.57189552
153Meningocele (HP:0002435)1.56601348
154Broad foot (HP:0001769)1.56459923
155Hypothermia (HP:0002045)1.55392386
156Oligodactyly (hands) (HP:0001180)1.55141901

Predicted kinase interactions (KEA)

RankGene SetZ-score
1CASK4.79912303
2NTRK34.38942469
3MAP3K43.80172578
4MARK13.54217078
5MAP3K123.53836254
6MAP2K73.36498544
7LATS13.17249644
8STK38L3.15291593
9MAP3K92.91004861
10MAP2K42.48898166
11MINK12.40478865
12NTRK22.25675996
13FRK2.13932256
14CDK192.01916695
15EPHA41.86980979
16INSRR1.84310393
17BMPR1B1.82851149
18DAPK21.73420792
19PLK21.71502755
20PNCK1.65007690
21MAPK131.63123524
22PAK61.51861001
23EPHB21.47275364
24TRIM281.45979079
25KSR11.45928334
26DAPK11.43910031
27MAP4K21.43334850
28CAMKK21.42272565
29PRKCG1.39714145
30PRPF4B1.37317804
31TNIK1.37244461
32AKT31.34757787
33ZAK1.33678130
34FGFR21.33349282
35CDK51.27736153
36TIE11.25068989
37GRK51.24985082
38WEE11.24068964
39KSR21.20432142
40OXSR11.19918090
41CAMKK11.17043338
42MKNK11.15721535
43STK391.15217718
44TSSK61.14315910
45RIPK41.13581510
46PHKG11.09776160
47PHKG21.09776160
48CSNK1A1L1.08738528
49CSNK1G31.05789862
50SGK21.04495352
51CAMK2A1.04155403
52ARAF1.01359375
53SGK2230.98933114
54SGK4940.98933114
55SIK30.97933501
56STK380.95319290
57LATS20.95294817
58CSNK1G10.94049913
59NTRK10.93289669
60MKNK20.92832396
61CDK30.92794476
62CCNB10.92239603
63ERBB20.89910999
64PDK30.88893052
65PDK40.88893052
66CDK180.88872358
67GRK70.83991219
68MAP3K60.83703296
69SIK20.83618169
70CDK150.83486798
71ERBB30.82634699
72UHMK10.82396466
73FES0.79396466
74CDK140.77739265
75ADRBK20.77147978
76CAMK2B0.74128064
77ERBB40.73778010
78CSNK1G20.71790090
79NME10.71156089
80PRKCE0.70175476
81CDK11A0.69786193
82WNK30.69595273
83TAOK10.68218109
84MAPK150.68024453
85BRAF0.67831305
86SGK30.67443182
87SGK10.66794477
88DYRK1A0.66116324
89TAOK30.65737732
90TAF10.64688361
91TGFBR10.63847109
92WNK10.63494391
93BMPR20.63220178
94DYRK1B0.63211042
95PAK30.62816339
96STK110.62439463
97NEK10.59616795
98CAMK2G0.57994855
99BCR0.56611788
100TYRO30.56007308
101VRK10.55910510
102NEK60.55412049
103CAMK10.54885572
104DYRK30.53814420
105ADRBK10.53766419
106PRKACB0.52828073
107RAF10.50314028
108MARK20.49874249
109STK160.49530147
110PRKCH0.48980288
111RET0.48536928
112PLK30.47838463
113TNK20.47796311
114CSNK1A10.47243684
115RPS6KA30.46130104
116STK30.45379955
117CAMK1G0.45274066
118CAMK2D0.44986598
119TTK0.44572441
120PRKD30.41976214
121CSNK1D0.41534722
122PRKCZ0.41382062
123BUB10.40903489
124ROCK20.40652354
125RPS6KA40.39197237
126MAPK120.38816621
127PINK10.38716616
128AURKA0.38351299
129DYRK20.38159305
130MAP3K20.37443869
131CSNK1E0.36896098
132PTK2B0.35831752
133PRKG10.35164639
134PRKACA0.35156320
135PKN10.35003710
136FYN0.34958343
137PDK20.34604367
138PDK10.34038917
139RPS6KA20.33742605
140CHEK20.33458479

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050334.59472640
2Synaptic vesicle cycle_Homo sapiens_hsa047213.83652112
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.98152215
4GABAergic synapse_Homo sapiens_hsa047272.90030155
5Collecting duct acid secretion_Homo sapiens_hsa049662.73878405
6Morphine addiction_Homo sapiens_hsa050322.66984762
7Circadian entrainment_Homo sapiens_hsa047132.56264541
8Glutamatergic synapse_Homo sapiens_hsa047242.55746275
9Olfactory transduction_Homo sapiens_hsa047402.49637920
10Long-term potentiation_Homo sapiens_hsa047202.42139851
11Amphetamine addiction_Homo sapiens_hsa050312.22061883
12Dopaminergic synapse_Homo sapiens_hsa047282.08187942
13Long-term depression_Homo sapiens_hsa047302.07024927
14Taste transduction_Homo sapiens_hsa047422.02472447
15Salivary secretion_Homo sapiens_hsa049701.93366234
16Insulin secretion_Homo sapiens_hsa049111.80080860
17Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.74872080
18Serotonergic synapse_Homo sapiens_hsa047261.73706102
19Vibrio cholerae infection_Homo sapiens_hsa051101.67136118
20Cholinergic synapse_Homo sapiens_hsa047251.66196038
21Nitrogen metabolism_Homo sapiens_hsa009101.64367183
22Gastric acid secretion_Homo sapiens_hsa049711.63414581
23Renin secretion_Homo sapiens_hsa049241.54506796
24Aldosterone synthesis and secretion_Homo sapiens_hsa049251.48034183
25Calcium signaling pathway_Homo sapiens_hsa040201.45850327
26Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.45501978
27Oxidative phosphorylation_Homo sapiens_hsa001901.44519848
28Cocaine addiction_Homo sapiens_hsa050301.42986424
29Taurine and hypotaurine metabolism_Homo sapiens_hsa004301.40839291
30Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.39832152
31Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.37616207
32Oxytocin signaling pathway_Homo sapiens_hsa049211.36930308
33Hedgehog signaling pathway_Homo sapiens_hsa043401.34359306
34Basal cell carcinoma_Homo sapiens_hsa052171.29332077
35Gap junction_Homo sapiens_hsa045401.28908122
36Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051201.28110379
37GnRH signaling pathway_Homo sapiens_hsa049121.22632703
38Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.21806650
39Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.18863004
40Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.13502765
41Cardiac muscle contraction_Homo sapiens_hsa042601.13207152
42Protein export_Homo sapiens_hsa030601.12473493
43Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.10128867
44cAMP signaling pathway_Homo sapiens_hsa040241.05581008
45Type II diabetes mellitus_Homo sapiens_hsa049301.05124532
46Axon guidance_Homo sapiens_hsa043601.04782423
47Estrogen signaling pathway_Homo sapiens_hsa049151.02127353
48Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.98640499
49Phosphatidylinositol signaling system_Homo sapiens_hsa040700.98265262
50Alzheimers disease_Homo sapiens_hsa050100.98043933
51Parkinsons disease_Homo sapiens_hsa050120.93638126
52Steroid biosynthesis_Homo sapiens_hsa001000.93616888
53Tryptophan metabolism_Homo sapiens_hsa003800.91703727
54Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.91285281
55Propanoate metabolism_Homo sapiens_hsa006400.90758835
56Hippo signaling pathway_Homo sapiens_hsa043900.89634133
57ErbB signaling pathway_Homo sapiens_hsa040120.89184404
58cGMP-PKG signaling pathway_Homo sapiens_hsa040220.84720484
59Phototransduction_Homo sapiens_hsa047440.83836726
60Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.83091120
61Melanogenesis_Homo sapiens_hsa049160.82089849
62Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.81437941
63Oocyte meiosis_Homo sapiens_hsa041140.80744645
64Histidine metabolism_Homo sapiens_hsa003400.79299521
65Vascular smooth muscle contraction_Homo sapiens_hsa042700.79080467
66Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.78945299
67Glioma_Homo sapiens_hsa052140.77088621
68Maturity onset diabetes of the young_Homo sapiens_hsa049500.76629317
69Basal transcription factors_Homo sapiens_hsa030220.76242587
70Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71102237
71Huntingtons disease_Homo sapiens_hsa050160.70351244
72Fanconi anemia pathway_Homo sapiens_hsa034600.68595836
73Rheumatoid arthritis_Homo sapiens_hsa053230.68188456
74Dilated cardiomyopathy_Homo sapiens_hsa054140.65190093
75Thyroid hormone synthesis_Homo sapiens_hsa049180.64280844
76Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.63822834
77Type I diabetes mellitus_Homo sapiens_hsa049400.62859373
78Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.61922589
79Pancreatic secretion_Homo sapiens_hsa049720.61362166
80MAPK signaling pathway_Homo sapiens_hsa040100.61020751
81ECM-receptor interaction_Homo sapiens_hsa045120.53590911
82Dorso-ventral axis formation_Homo sapiens_hsa043200.53179565
83TGF-beta signaling pathway_Homo sapiens_hsa043500.52951372
84Phagosome_Homo sapiens_hsa041450.52534295
85Phospholipase D signaling pathway_Homo sapiens_hsa040720.52473716
86Choline metabolism in cancer_Homo sapiens_hsa052310.52434623
87beta-Alanine metabolism_Homo sapiens_hsa004100.51007852
88Folate biosynthesis_Homo sapiens_hsa007900.50979562
89Phenylalanine metabolism_Homo sapiens_hsa003600.50640378
90Cysteine and methionine metabolism_Homo sapiens_hsa002700.50390049
91Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.49411670
92Ovarian steroidogenesis_Homo sapiens_hsa049130.48843239
93Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.47595604
94Alcoholism_Homo sapiens_hsa050340.47254722
95Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.47189335
96Ras signaling pathway_Homo sapiens_hsa040140.46465412
97Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.45922957
98Glucagon signaling pathway_Homo sapiens_hsa049220.45282928
99Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.45007472
100Ether lipid metabolism_Homo sapiens_hsa005650.44962089
101Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.44680793
102Inositol phosphate metabolism_Homo sapiens_hsa005620.44609641
103Butanoate metabolism_Homo sapiens_hsa006500.44525036
104Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.43917792
105Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.43320896
106Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.41869569
107RNA degradation_Homo sapiens_hsa030180.40443708
108Pyruvate metabolism_Homo sapiens_hsa006200.39918274
109ABC transporters_Homo sapiens_hsa020100.37689894
110Peroxisome_Homo sapiens_hsa041460.36712597
111Circadian rhythm_Homo sapiens_hsa047100.36144606
112Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.36009535
113Renal cell carcinoma_Homo sapiens_hsa052110.35206916
114Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.33732245
115Primary bile acid biosynthesis_Homo sapiens_hsa001200.33302664
1162-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.33205946
117Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.32854105
118Rap1 signaling pathway_Homo sapiens_hsa040150.30857423
119Neurotrophin signaling pathway_Homo sapiens_hsa047220.30529494
120Melanoma_Homo sapiens_hsa052180.29783911
121Sphingolipid signaling pathway_Homo sapiens_hsa040710.29504357
122Wnt signaling pathway_Homo sapiens_hsa043100.29200942
123Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.28849475
124Endometrial cancer_Homo sapiens_hsa052130.28586003
125Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.28525776
126Thyroid hormone signaling pathway_Homo sapiens_hsa049190.28365604
127Bile secretion_Homo sapiens_hsa049760.27520177
128Carbohydrate digestion and absorption_Homo sapiens_hsa049730.27438094
129Prion diseases_Homo sapiens_hsa050200.27169055
130Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.26763767
131Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.26573622

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