CNTNAP1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of short-term neuronal synaptic plasticity (GO:0048172)6.27133696
2synaptic vesicle maturation (GO:0016188)6.21297266
3locomotory exploration behavior (GO:0035641)6.09107735
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.90693456
5positive regulation of calcium ion-dependent exocytosis (GO:0045956)5.69838226
6vocalization behavior (GO:0071625)5.44459794
7synaptic vesicle exocytosis (GO:0016079)5.26009260
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act5.18941191
9glutamate secretion (GO:0014047)5.07177247
10regulation of synaptic vesicle exocytosis (GO:2000300)5.00995895
11synaptic vesicle docking involved in exocytosis (GO:0016081)4.95862697
12ionotropic glutamate receptor signaling pathway (GO:0035235)4.90588592
13regulation of glutamate receptor signaling pathway (GO:1900449)4.89396096
14neurotransmitter secretion (GO:0007269)4.73389492
15regulation of long-term neuronal synaptic plasticity (GO:0048169)4.67031087
16regulation of neuronal synaptic plasticity (GO:0048168)4.65255554
17cellular potassium ion homeostasis (GO:0030007)4.56373568
18exploration behavior (GO:0035640)4.51025855
19gamma-aminobutyric acid transport (GO:0015812)4.50408219
20regulation of synapse structural plasticity (GO:0051823)4.50132865
21regulation of synaptic vesicle transport (GO:1902803)4.49149673
22sodium ion export (GO:0071436)4.39861203
23protein localization to synapse (GO:0035418)4.38470607
24membrane depolarization during cardiac muscle cell action potential (GO:0086012)4.36075026
25synaptic transmission, glutamatergic (GO:0035249)4.35089692
26glutamate receptor signaling pathway (GO:0007215)4.33987279
27amino acid import (GO:0043090)4.26164491
28long-term memory (GO:0007616)4.25110985
29neuron-neuron synaptic transmission (GO:0007270)4.15167437
30neurotransmitter-gated ion channel clustering (GO:0072578)4.06895148
31layer formation in cerebral cortex (GO:0021819)4.05788133
32* neuronal action potential propagation (GO:0019227)4.04046799
33dendritic spine morphogenesis (GO:0060997)4.00587082
34regulation of excitatory postsynaptic membrane potential (GO:0060079)3.93428725
35positive regulation of membrane potential (GO:0045838)3.90968287
36cerebellar Purkinje cell differentiation (GO:0021702)3.90300078
37regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.88321698
38cytoskeletal anchoring at plasma membrane (GO:0007016)3.85422483
39glycine transport (GO:0015816)3.85369986
40postsynaptic membrane organization (GO:0001941)3.83747341
41neurotransmitter transport (GO:0006836)3.81211391
42prepulse inhibition (GO:0060134)3.78258987
43neuron cell-cell adhesion (GO:0007158)3.77318756
44proline transport (GO:0015824)3.76313879
45regulation of postsynaptic membrane potential (GO:0060078)3.72860086
46* neuromuscular process controlling balance (GO:0050885)3.70098478
47cell communication by electrical coupling involved in cardiac conduction (GO:0086064)3.69194169
48positive regulation of dendritic spine development (GO:0060999)3.68090361
49activation of protein kinase A activity (GO:0034199)3.67631381
50transmission of nerve impulse (GO:0019226)3.67513953
51regulation of synapse maturation (GO:0090128)3.65592691
52regulation of synaptic plasticity (GO:0048167)3.64133139
53regulation of dendritic spine morphogenesis (GO:0061001)3.63424344
54positive regulation of synaptic transmission, dopaminergic (GO:0032226)3.63370775
55regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.59266562
56regulation of neurotransmitter levels (GO:0001505)3.58951316
57positive regulation of synapse maturation (GO:0090129)3.54144557
58auditory behavior (GO:0031223)3.52250950
59positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.51756239
60negative regulation of dendrite morphogenesis (GO:0050774)3.51491572
61G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.47972965
62regulation of synaptic transmission, glutamatergic (GO:0051966)3.47766021
63central nervous system myelination (GO:0022010)3.45909990
64axon ensheathment in central nervous system (GO:0032291)3.45909990
65membrane depolarization during action potential (GO:0086010)3.45718687
66gamma-aminobutyric acid signaling pathway (GO:0007214)3.44619676
67regulation of neurotransmitter secretion (GO:0046928)3.43767455
68cell communication by electrical coupling (GO:0010644)3.42015648
69synaptic vesicle endocytosis (GO:0048488)3.40999505
70positive regulation of synaptic transmission, GABAergic (GO:0032230)3.40388222
71long-term synaptic potentiation (GO:0060291)3.38422059
72positive regulation of dendritic spine morphogenesis (GO:0061003)3.37541291
73response to auditory stimulus (GO:0010996)3.37382311
74membrane hyperpolarization (GO:0060081)3.33906851
75neuronal ion channel clustering (GO:0045161)3.33553552
76membrane depolarization (GO:0051899)3.31238107
77positive regulation of neurotransmitter transport (GO:0051590)3.29468831
78L-amino acid import (GO:0043092)3.29365439
79regulation of vesicle fusion (GO:0031338)3.28786813
80regulation of neurotransmitter transport (GO:0051588)3.27678956
81regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)3.27450179
82potassium ion import (GO:0010107)3.27029269
83positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.26403693
84negative regulation of synaptic transmission, GABAergic (GO:0032229)3.22539584
85regulation of ARF protein signal transduction (GO:0032012)3.20728514
86cerebellar Purkinje cell layer development (GO:0021680)3.17551642
87cerebellar granule cell differentiation (GO:0021707)3.17051882
88positive regulation of neurotransmitter secretion (GO:0001956)3.15923200
89negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.15607411
90adult walking behavior (GO:0007628)3.13586745
91regulation of voltage-gated calcium channel activity (GO:1901385)3.12185605
92cellular sodium ion homeostasis (GO:0006883)3.08915666
93potassium ion homeostasis (GO:0055075)3.07096083
94G-protein coupled acetylcholine receptor signaling pathway (GO:0007213)3.07086792
95neuron recognition (GO:0008038)3.06818854
96mating behavior (GO:0007617)3.06014965
97learning (GO:0007612)3.05778165
98* neuromuscular process (GO:0050905)3.04005907
99positive regulation of synaptic transmission (GO:0050806)3.03769706
100regulation of synaptic transmission (GO:0050804)3.02583972
101synaptic transmission (GO:0007268)3.00970853
102vesicle docking involved in exocytosis (GO:0006904)3.00945405
103long term synaptic depression (GO:0060292)3.00834016
104behavioral fear response (GO:0001662)3.00803401
105behavioral defense response (GO:0002209)3.00803401
106vesicle transport along microtubule (GO:0047496)2.99315396
107dendritic spine organization (GO:0097061)2.99237222
108behavioral response to cocaine (GO:0048148)2.98659624
109* neuromuscular process controlling posture (GO:0050884)2.98655128
110dendrite morphogenesis (GO:0048813)2.98048739
111regulation of dendritic spine development (GO:0060998)2.97302938
112positive regulation of dendrite development (GO:1900006)2.95785874
113positive regulation of fibroblast migration (GO:0010763)2.95679249
114acidic amino acid transport (GO:0015800)2.92659229
115cell migration in hindbrain (GO:0021535)2.80554493
116regulation of respiratory gaseous exchange by neurological system process (GO:0002087)2.77123133
117cell differentiation in hindbrain (GO:0021533)2.76022898
118vesicle docking (GO:0048278)2.74167506
119response to gravity (GO:0009629)2.70033229
120regulation of dendrite morphogenesis (GO:0048814)2.68663122
121dicarboxylic acid transport (GO:0006835)2.68328296
122neuromuscular synaptic transmission (GO:0007274)2.67123025
123establishment of synaptic vesicle localization (GO:0097480)2.60410491

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human5.82426755
2SUZ12_18555785_ChIP-Seq_MESCs_Mouse3.15430125
3* SUZ12_18692474_ChIP-Seq_MESCs_Mouse3.10290749
4JARID2_20064375_ChIP-Seq_MESCs_Mouse3.05598577
5GBX2_23144817_ChIP-Seq_PC3_Human2.99739728
6* RARB_27405468_Chip-Seq_BRAIN_Mouse2.91321789
7DROSHA_22980978_ChIP-Seq_HELA_Human2.86103456
8* RNF2_18974828_ChIP-Seq_MESCs_Mouse2.81954227
9* EZH2_18974828_ChIP-Seq_MESCs_Mouse2.81954227
10REST_21632747_ChIP-Seq_MESCs_Mouse2.77427665
11JARID2_20075857_ChIP-Seq_MESCs_Mouse2.71567237
12* MTF2_20144788_ChIP-Seq_MESCs_Mouse2.61927836
13* SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.58636370
14* SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.56987959
15IKZF1_21737484_ChIP-ChIP_HCT116_Human2.51001454
16* SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.45905432
17* SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.45313183
18MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human2.40959457
19EZH2_27304074_Chip-Seq_ESCs_Mouse2.36632322
20PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse2.36219202
21* SUZ12_27294783_Chip-Seq_ESCs_Mouse2.30364015
22REST_18959480_ChIP-ChIP_MESCs_Mouse2.29952862
23EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.29374316
24* EZH2_27294783_Chip-Seq_ESCs_Mouse2.28928452
25RNF2_27304074_Chip-Seq_ESCs_Mouse2.22284332
26* EED_16625203_ChIP-ChIP_MESCs_Mouse2.15225809
27TRIM28_21343339_ChIP-Seq_HEK293_Human2.07065470
28ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.89159303
29CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.87532738
30AR_21572438_ChIP-Seq_LNCaP_Human1.80048482
31ERG_21242973_ChIP-ChIP_JURKAT_Human1.77262643
32RARG_19884340_ChIP-ChIP_MEFs_Mouse1.76625835
33LXR_22292898_ChIP-Seq_THP-1_Human1.74764306
34NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.72834576
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.56956770
36ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.55203254
37GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51143542
38SMAD4_21799915_ChIP-Seq_A2780_Human1.49429320
39CTBP2_25329375_ChIP-Seq_LNCAP_Human1.43284200
40DNAJC2_21179169_ChIP-ChIP_NT2_Human1.41647355
41EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.40628629
42RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.40390779
43SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.38962450
44KDM2B_26808549_Chip-Seq_K562_Human1.35028064
45SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.34960890
46RING1B_27294783_Chip-Seq_ESCs_Mouse1.33954720
47ESR2_21235772_ChIP-Seq_MCF-7_Human1.32081540
48OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.29198506
49* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.29071673
50CTBP1_25329375_ChIP-Seq_LNCAP_Human1.28157141
51AR_19668381_ChIP-Seq_PC3_Human1.24535989
52* WT1_25993318_ChIP-Seq_PODOCYTE_Human1.24150588
53TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.24078586
54SOX2_21211035_ChIP-Seq_LN229_Gbm1.23915654
55SMAD_19615063_ChIP-ChIP_OVARY_Human1.23535863
56TAF15_26573619_Chip-Seq_HEK293_Human1.23338109
57* EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.21542540
58SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.20577821
59ZNF274_21170338_ChIP-Seq_K562_Hela1.20311086
60TP53_20018659_ChIP-ChIP_R1E_Mouse1.19532806
61UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.19253836
62NR3C1_23031785_ChIP-Seq_PC12_Mouse1.18992458
63PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.18538221
64TP53_23651856_ChIP-Seq_MEFs_Mouse1.17452654
65* ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.16843316
66KDM2B_26808549_Chip-Seq_DND41_Human1.16040668
67ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.14889711
68STAT3_23295773_ChIP-Seq_U87_Human1.14840877
69WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.14516742
70GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.13649804
71RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.13645044
72* PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.13411529
73ZFP281_18757296_ChIP-ChIP_E14_Mouse1.12141540
74AR_25329375_ChIP-Seq_VCAP_Human1.09998191
75RING1B_27294783_Chip-Seq_NPCs_Mouse1.09396425
76SMAD3_21741376_ChIP-Seq_EPCs_Human1.09294751
77CTNNB1_20460455_ChIP-Seq_HCT116_Human1.07237676
78KDM2B_26808549_Chip-Seq_JURKAT_Human1.06935970
79TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.06804729
80CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.06049674
81* RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.05699512
82ZNF217_24962896_ChIP-Seq_MCF-7_Human1.05554496
83P53_22127205_ChIP-Seq_FIBROBLAST_Human1.05352672
84PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.04465014
85SMC4_20622854_ChIP-Seq_HELA_Human1.04364193
86SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03081970
87P300_19829295_ChIP-Seq_ESCs_Human1.02590370
88TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human1.00763721
89NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.00367708
90CDX2_19796622_ChIP-Seq_MESCs_Mouse1.00002726
91MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.99662950
92TCF4_23295773_ChIP-Seq_U87_Human0.99080892
93GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97247872
94RCOR2_21632747_ChIP-Seq_MESCs_Mouse0.96217596
95SMAD3_21741376_ChIP-Seq_HESCs_Human0.95741821
96YAP1_20516196_ChIP-Seq_MESCs_Mouse0.95457919
97ARNT_22903824_ChIP-Seq_MCF-7_Human0.94773379
98AHR_22903824_ChIP-Seq_MCF-7_Human0.94421040
99TP53_16413492_ChIP-PET_HCT116_Human0.94293532
100TOP2B_26459242_ChIP-Seq_MCF-7_Human0.93946959
101P300_27058665_Chip-Seq_ZR-75-30cells_Human0.93907379
102CREB1_26743006_Chip-Seq_LNCaP_Human0.93687930
103ZFP57_27257070_Chip-Seq_ESCs_Mouse0.93428474
104THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.93291773
105RXR_22108803_ChIP-Seq_LS180_Human0.92605909
106EP300_21415370_ChIP-Seq_HL-1_Mouse0.92327447
107PIAS1_25552417_ChIP-Seq_VCAP_Human0.92166047
108* TET1_21490601_ChIP-Seq_MESCs_Mouse0.91824569
109SMAD3_21741376_ChIP-Seq_ESCs_Human0.91657720
110* ZFP281_27345836_Chip-Seq_ESCs_Mouse0.91174646
111OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.90755303
112CTCF_27219007_Chip-Seq_Bcells_Human0.90626228
113SMAD4_21741376_ChIP-Seq_HESCs_Human0.90571540
114CBX2_27304074_Chip-Seq_ESCs_Mouse0.90386673
115GATA1_26923725_Chip-Seq_HPCs_Mouse0.90338173
116SRY_22984422_ChIP-ChIP_TESTIS_Rat0.89775665
117TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.89330651
118SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.89030930
119SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.87689743
120VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human0.87176051
121MYC_19915707_ChIP-ChIP_AK7_Human0.87115050
122KDM2B_26808549_Chip-Seq_SIL-ALL_Human0.86864090
123PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse0.86317203
124DPY_21335234_ChIP-Seq_ESCs_Mouse0.85905062
125NR3C1_21868756_ChIP-Seq_MCF10A_Human0.85195204
126SMC1_22415368_ChIP-Seq_MEFs_Mouse0.84933608
127RUNX2_22187159_ChIP-Seq_PCA_Human0.84509893
128BMI1_23680149_ChIP-Seq_NPCS_Mouse0.84505443
129ELK3_25401928_ChIP-Seq_HUVEC_Human0.84314750
130OCT4_19829295_ChIP-Seq_ESCs_Human0.83378378
131AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.83248769
132TP53_22127205_ChIP-Seq_IMR90_Human0.82664891
133RNF2_27304074_Chip-Seq_NSC_Mouse0.81926985
134PRDM14_20953172_ChIP-Seq_ESCs_Human0.81580084
135TET1_21451524_ChIP-Seq_MESCs_Mouse0.80881202
136RUNX1_26923725_Chip-Seq_HPCs_Mouse0.80682214
137* KLF4_19829295_ChIP-Seq_ESCs_Human0.80625017
138TFAP2A_17053090_ChIP-ChIP_MCF-7_Human0.80588738
139KDM2B_26808549_Chip-Seq_SUP-B15_Human0.80218646
140SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.77415381
141NFIB_24661679_ChIP-Seq_LUNG_Mouse0.77326689

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0004859_abnormal_synaptic_plasticity6.98326128
2MP0003880_abnormal_central_pattern4.64521817
3MP0003635_abnormal_synaptic_transmissio4.37938728
4MP0002822_catalepsy3.74750592
5MP0009745_abnormal_behavioral_response3.63154188
6MP0004270_analgesia3.61566093
7* MP0009046_muscle_twitch3.42518644
8MP0002064_seizures3.37690710
9MP0002063_abnormal_learning/memory/cond3.37604800
10MP0008438_abnormal_cutaneous_collagen3.15562301
11MP0001968_abnormal_touch/_nociception2.96044043
12MP0005423_abnormal_somatic_nervous2.94078411
13MP0002572_abnormal_emotion/affect_behav2.81621168
14* MP0002272_abnormal_nervous_system2.80054617
15MP0001486_abnormal_startle_reflex2.71807504
16MP0002734_abnormal_mechanical_nocicepti2.62253078
17MP0001501_abnormal_sleep_pattern2.51949407
18MP0002736_abnormal_nociception_after2.21026255
19* MP0008569_lethality_at_weaning2.16357163
20MP0001348_abnormal_lacrimal_gland2.13860657
21MP0002735_abnormal_chemical_nociception2.08751234
22MP0001440_abnormal_grooming_behavior2.06230790
23MP0002067_abnormal_sensory_capabilities2.02576191
24MP0003705_abnormal_hypodermis_morpholog2.02037374
25MP0001970_abnormal_pain_threshold1.96539526
26MP0002733_abnormal_thermal_nociception1.96164980
27MP0002909_abnormal_adrenal_gland1.90892233
28MP0003329_amyloid_beta_deposits1.88799728
29MP0001958_emphysema1.80139326
30MP0004858_abnormal_nervous_system1.78522176
31MP0002184_abnormal_innervation1.77193359
32MP0003279_aneurysm1.76827681
33MP0004811_abnormal_neuron_physiology1.76601505
34MP0005386_behavior/neurological_phenoty1.75470690
35MP0004924_abnormal_behavior1.75470690
36MP0005503_abnormal_tendon_morphology1.71531939
37MP0002557_abnormal_social/conspecific_i1.70529465
38MP0009780_abnormal_chondrocyte_physiolo1.70055554
39MP0005646_abnormal_pituitary_gland1.64998096
40MP0003879_abnormal_hair_cell1.61010946
41MP0004885_abnormal_endolymph1.57639906
42MP0000955_abnormal_spinal_cord1.54697754
43MP0003633_abnormal_nervous_system1.48672648
44* MP0002066_abnormal_motor_capabilities/c1.45913554
45MP0004142_abnormal_muscle_tone1.41418395
46MP0000778_abnormal_nervous_system1.40020233
47MP0001984_abnormal_olfaction1.36717013
48* MP0002882_abnormal_neuron_morphology1.35603593
49MP0003787_abnormal_imprinting1.28917665
50MP0001502_abnormal_circadian_rhythm1.25041899
51MP0003631_nervous_system_phenotype1.24905023
52MP0008872_abnormal_physiological_respon1.23360644
53MP0001529_abnormal_vocalization1.22958050
54MP0006276_abnormal_autonomic_nervous1.21797299
55MP0004145_abnormal_muscle_electrophysio1.20558322
56MP0003690_abnormal_glial_cell1.14897604
57MP0005645_abnormal_hypothalamus_physiol1.14768808
58MP0003123_paternal_imprinting1.14024284
59MP0003075_altered_response_to1.13253752
60MP0005257_abnormal_intraocular_pressure1.07953129
61MP0003283_abnormal_digestive_organ1.06879662
62MP0008874_decreased_physiological_sensi1.05745055
63MP0002229_neurodegeneration1.03394072
64MP0000751_myopathy1.03039342
65MP0001177_atelectasis1.02951128
66* MP0002152_abnormal_brain_morphology1.01745991
67MP0001905_abnormal_dopamine_level1.01009035
68MP0004272_abnormal_basement_membrane1.00021324
69MP0005275_abnormal_skin_tensile0.98502748
70MP0008961_abnormal_basal_metabolism0.97425466
71MP0000569_abnormal_digit_pigmentation0.97060649
72MP0003632_abnormal_nervous_system0.94269120
73MP0005167_abnormal_blood-brain_barrier0.94022155
74MP0000013_abnormal_adipose_tissue0.92870422
75MP0001346_abnormal_lacrimal_gland0.91651870
76MP0004742_abnormal_vestibular_system0.89606799
77* MP0002069_abnormal_eating/drinking_beha0.89049593
78MP0005535_abnormal_body_temperature0.88537241
79MP0000604_amyloidosis0.86559143
80* MP0000920_abnormal_myelination0.86171532
81MP0002295_abnormal_pulmonary_circulatio0.86169355
82MP0004085_abnormal_heartbeat0.85989979
83MP0003634_abnormal_glial_cell0.83289170
84MP0000534_abnormal_ureter_morphology0.82783902
85MP0003122_maternal_imprinting0.82707610
86MP0002089_abnormal_postnatal_growth/wei0.81584970
87* MP0005551_abnormal_eye_electrophysiolog0.80249518
88MP0002090_abnormal_vision0.79997175
89MP0005171_absent_coat_pigmentation0.79723573
90MP0001188_hyperpigmentation0.79275274
91MP0003091_abnormal_cell_migration0.77879067
92MP0004510_myositis0.75812414
93MP0010368_abnormal_lymphatic_system0.75234862
94MP0001849_ear_inflammation0.75117431
95MP0003385_abnormal_body_wall0.74957140
96MP0010386_abnormal_urinary_bladder0.73620330
97MP0004215_abnormal_myocardial_fiber0.71957250
98MP0001963_abnormal_hearing_physiology0.70727002
99MP0009384_cardiac_valve_regurgitation0.70644011
100MP0005499_abnormal_olfactory_system0.70452213
101MP0005394_taste/olfaction_phenotype0.70452213
102MP0003137_abnormal_impulse_conducting0.69932670
103MP0001485_abnormal_pinna_reflex0.68116740
104MP0005409_darkened_coat_color0.66376012
105MP0002249_abnormal_larynx_morphology0.66075672
106MP0004043_abnormal_pH_regulation0.65822677
107MP0002752_abnormal_somatic_nervous0.65387458
108MP0005623_abnormal_meninges_morphology0.65255880
109MP0003566_abnormal_cell_adhesion0.64923602
110MP0010234_abnormal_vibrissa_follicle0.64543881
111MP0005388_respiratory_system_phenotype0.64513087
112MP0002133_abnormal_respiratory_system0.64513087
113MP0005508_abnormal_skeleton_morphology0.64155152
114MP0004484_altered_response_of0.63582782
115MP0004233_abnormal_muscle_weight0.62181283
116MP0000747_muscle_weakness0.59832851
117MP0000003_abnormal_adipose_tissue0.59087786
118MP0003172_abnormal_lysosome_physiology0.58877632
119MP0005595_abnormal_vascular_smooth0.58754369
120MP0001299_abnormal_eye_distance/0.56556056
121MP0003045_fibrosis0.55499262
122MP0003861_abnormal_nervous_system0.54029324
123MP0002896_abnormal_bone_mineralization0.54005732
124MP0000631_abnormal_neuroendocrine_gland0.53204284
125MP0001664_abnormal_digestion0.52002065
126MP0002638_abnormal_pupillary_reflex0.51797505
127* MP0010769_abnormal_survival0.51621602
128MP0001943_abnormal_respiration0.51546076
129* MP0010768_mortality/aging0.48142749
130* MP0003956_abnormal_body_size0.48118880

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)7.93906738
2Myokymia (HP:0002411)7.74080860
3Focal seizures (HP:0007359)6.05400290
4Visual hallucinations (HP:0002367)5.52372440
5Action tremor (HP:0002345)5.13579075
6Progressive cerebellar ataxia (HP:0002073)4.83002400
7Atonic seizures (HP:0010819)4.62365483
8Febrile seizures (HP:0002373)4.54881441
9Protrusio acetabuli (HP:0003179)4.41108164
10Epileptic encephalopathy (HP:0200134)4.38853034
11Premature rupture of membranes (HP:0001788)4.19857355
12Absence seizures (HP:0002121)4.17866594
13Generalized tonic-clonic seizures (HP:0002069)3.99904035
14Gaze-evoked nystagmus (HP:0000640)3.94966012
15Dysdiadochokinesis (HP:0002075)3.79863151
16Dialeptic seizures (HP:0011146)3.75591894
17Supranuclear gaze palsy (HP:0000605)3.70641825
18Ankle clonus (HP:0011448)3.62544354
19Poor eye contact (HP:0000817)3.59348972
20Depression (HP:0000716)3.51770447
21Impaired vibration sensation in the lower limbs (HP:0002166)3.51584200
22Dysmetria (HP:0001310)3.50592853
23Broad-based gait (HP:0002136)3.49700770
24Impaired social interactions (HP:0000735)3.33941875
25Abnormal social behavior (HP:0012433)3.33941875
26Postural instability (HP:0002172)3.31406724
27Scanning speech (HP:0002168)3.29221179
28Hemiplegia (HP:0002301)3.27083124
29Anxiety (HP:0000739)3.27075905
30Urinary bladder sphincter dysfunction (HP:0002839)3.25109045
31Truncal ataxia (HP:0002078)3.22936224
32Impaired smooth pursuit (HP:0007772)3.19536694
33Intention tremor (HP:0002080)3.17148090
34Annular pancreas (HP:0001734)3.13292890
35Dysmetric saccades (HP:0000641)3.12899724
36Shallow orbits (HP:0000586)3.12132166
37Ventricular fibrillation (HP:0001663)3.10715960
38Abnormality of the lower motor neuron (HP:0002366)3.08854832
39Abnormal eating behavior (HP:0100738)3.02764011
40Genetic anticipation (HP:0003743)3.00500693
41Torticollis (HP:0000473)2.91648420
42Mutism (HP:0002300)2.90850747
43Vascular tortuosity (HP:0004948)2.88273245
44Papilledema (HP:0001085)2.86850289
45Abnormality of ocular smooth pursuit (HP:0000617)2.82781935
46Bladder diverticulum (HP:0000015)2.79123964
47Hemiparesis (HP:0001269)2.79036167
48Urinary urgency (HP:0000012)2.78156026
49Arterial tortuosity (HP:0005116)2.75469488
50Spastic gait (HP:0002064)2.72432608
51Cerebral aneurysm (HP:0004944)2.71427529
52Status epilepticus (HP:0002133)2.69051934
53Focal dystonia (HP:0004373)2.67174281
54Bowel diverticulosis (HP:0005222)2.64817114
55Abnormality of binocular vision (HP:0011514)2.63394320
56Diplopia (HP:0000651)2.63394320
57Aortic dissection (HP:0002647)2.61194744
58Upper limb amyotrophy (HP:0009129)2.61105386
59Distal upper limb amyotrophy (HP:0007149)2.61105386
60Amblyopia (HP:0000646)2.54692556
61Stereotypic behavior (HP:0000733)2.54399960
62Bradykinesia (HP:0002067)2.52427613
63Pointed chin (HP:0000307)2.47920408
64Broad metatarsal (HP:0001783)2.46319453
65Progressive inability to walk (HP:0002505)2.45949946
66Hyperacusis (HP:0010780)2.44805675
67Hand muscle atrophy (HP:0009130)2.41419731
68Impaired vibratory sensation (HP:0002495)2.41118019
69Mild short stature (HP:0003502)2.39246987
70Bundle branch block (HP:0011710)2.38855760
71Craniofacial dystonia (HP:0012179)2.38062661
72Neurofibrillary tangles (HP:0002185)2.35634353
73Hypoventilation (HP:0002791)2.33829487
74Cerebral hypomyelination (HP:0006808)2.32692990
75Aortic aneurysm (HP:0004942)2.32165957
76Turricephaly (HP:0000262)2.31259539
77Megalencephaly (HP:0001355)2.30181985
78Abnormality of saccadic eye movements (HP:0000570)2.29808608
79Tetraplegia (HP:0002445)2.28839182
80Hyperventilation (HP:0002883)2.27994562
81Wormian bones (HP:0002645)2.27282623
82Ankle contracture (HP:0006466)2.23122655
83Insomnia (HP:0100785)2.22541148
84Resting tremor (HP:0002322)2.22444813
85Sleep apnea (HP:0010535)2.20473013
86Cerebral inclusion bodies (HP:0100314)2.17909897
87Excessive salivation (HP:0003781)2.17282225
88Drooling (HP:0002307)2.17282225
89Bronchomalacia (HP:0002780)2.17115822
90Abnormality of dentin (HP:0010299)2.16642077
91Clonus (HP:0002169)2.16604286
92Neuronal loss in central nervous system (HP:0002529)2.15847613
93Lower limb muscle weakness (HP:0007340)2.14994658
94Fetal akinesia sequence (HP:0001989)2.12348998
95Termporal pattern (HP:0011008)2.11858070
96Insidious onset (HP:0003587)2.11858070
97Incomplete penetrance (HP:0003829)2.09181842
98Neonatal short-limb short stature (HP:0008921)2.08863594
99Apathy (HP:0000741)2.06895753
100Gait ataxia (HP:0002066)2.06392589
101Mitral regurgitation (HP:0001653)2.02452609
102Abnormality of the corticospinal tract (HP:0002492)2.02248951
103Abnormal EKG (HP:0003115)2.02117428
104Epileptiform EEG discharges (HP:0011182)2.02087271
105Pheochromocytoma (HP:0002666)1.99223866
106Lower limb asymmetry (HP:0100559)1.99210830
107Atrophic scars (HP:0001075)1.98320363
108EEG with generalized epileptiform discharges (HP:0011198)1.97221232
109Generalized myoclonic seizures (HP:0002123)1.97175441
110Renal duplication (HP:0000075)1.96665284
111Akinesia (HP:0002304)1.95469588
112Delusions (HP:0000746)1.94995890
113Absent speech (HP:0001344)1.93814493
114Spinal rigidity (HP:0003306)1.93783967
115Ankyloglossia (HP:0010296)1.93445900
116Lower limb amyotrophy (HP:0007210)1.93444941
117Fragile skin (HP:0001030)1.93138969
118Hyperextensible skin (HP:0000974)1.92772197
119Postural tremor (HP:0002174)1.92649628
120Genu recurvatum (HP:0002816)1.92379809
121Peripheral hypomyelination (HP:0007182)1.92213264
122Overgrowth (HP:0001548)1.92112578
123Soft skin (HP:0000977)1.90451413
124Agitation (HP:0000713)1.89859569
125Rigidity (HP:0002063)1.87746862
126Hypsarrhythmia (HP:0002521)1.87304991
127Prolonged QT interval (HP:0001657)1.85087892
128Psychosis (HP:0000709)1.84871464
129Cervical subluxation (HP:0003308)1.84526978
130Biconcave vertebral bodies (HP:0004586)1.82496168
131Type 1 muscle fiber predominance (HP:0003803)1.81481535
132Aplasia involving bones of the extremities (HP:0009825)1.81099438
133Aplasia involving bones of the upper limbs (HP:0009823)1.81099438
134Aplasia of the phalanges of the hand (HP:0009802)1.81099438
135Diminished motivation (HP:0000745)1.80762547
136Obstructive sleep apnea (HP:0002870)1.80667037
137Spinal canal stenosis (HP:0003416)1.80578807
138Dilatation of the ascending aorta (HP:0005111)1.79440144
139Rapidly progressive (HP:0003678)1.78029402
140Abnormality of the periventricular white matter (HP:0002518)1.76925364
141Limb ataxia (HP:0002070)1.74810266
142Horizontal nystagmus (HP:0000666)1.71675552
143Limb dystonia (HP:0002451)1.68596804

Predicted kinase interactions (KEA)

RankGene SetZ-score
1EPHA44.74212322
2NTRK34.61519998
3MAP3K93.93363185
4MAP3K42.77384370
5MINK12.65456009
6DAPK22.64921023
7PRKD32.48059747
8PAK62.45128537
9KSR22.37769174
10CAMKK12.31307103
11RIPK42.24959233
12MAP2K72.13437590
13NTRK22.06947007
14NTRK12.00818130
15STK381.93313299
16MARK11.90263750
17MAP2K41.86183571
18PDGFRA1.85887454
19CDK51.56622080
20MAP3K121.53483636
21CAMKK21.52211299
22MAP3K131.50430598
23FES1.42515023
24TNIK1.42382151
25KSR11.40698332
26DAPK11.39161249
27ARAF1.38869672
28PRPF4B1.36560329
29TYRO31.32116767
30TRIB31.28615171
31SIK21.28106268
32TAOK11.26097490
33GRK51.25545081
34CDK191.23527408
35MAP3K21.21431632
36PRKCG1.17784217
37PINK11.17364736
38RIPK11.13046933
39PRKCH1.10466128
40LIMK11.08747755
41UHMK11.08423792
42CAMK11.08130014
43PTK21.03401010
44WNK11.02598757
45SGK4941.02439422
46SGK2231.02439422
47STK111.02128902
48LMTK21.00023115
49PLK20.98408180
50MAPK130.97513133
51DDR20.97408525
52ICK0.94847494
53PNCK0.94509932
54MAPK120.92889238
55ALK0.92724501
56RET0.90049542
57TNK20.89956234
58CDK150.88474069
59CDK180.87373804
60SGK20.87299063
61CAMK2A0.87095770
62SGK30.86516768
63RAF10.85708403
64PAK20.85535806
65TESK10.84505576
66LATS20.82857240
67CDK140.80279410
68FGFR20.79542917
69PDK10.78796082
70CDK11A0.76737142
71BMPR20.75164725
72PHKG20.75088549
73PHKG10.75088549
74PDPK10.74372827
75CAMK2B0.72726771
76SGK10.72492213
77PTK2B0.71163907
78TTN0.71110353
79MAP3K10.70104986
80MARK20.69258373
81CDC42BPA0.66847424
82EEF2K0.66538968
83NEK60.65585636
84OXSR10.65583420
85MOS0.63206371
86NEK10.61863504
87CASK0.61567734
88RPS6KA20.61376188
89BRAF0.59483928
90PAK30.59156955
91DYRK1A0.58710346
92CAMK40.57602411
93RPS6KA30.57051328
94FGFR40.55962720
95ROCK10.55887043
96BRSK10.54262745
97CAMK1G0.53824819
98CAMK2G0.53566355
99MAP3K70.53320684
100MAPK100.52909576
101PKN10.50312005
102FYN0.47829277
103CAMK2D0.47613993
104PRKG20.46685981
105PRKCZ0.45655359
106PDGFRB0.40870851
107MAP2K10.40055412
108SCYL20.39409582
109MAPKAPK50.39328705
110SRC0.38613027
111DMPK0.38502957
112MAPK70.38464382
113DAPK30.37974223
114SMG10.37865214
115FER0.37799649
116MYLK0.37377937
117PRKD20.36965915
118PRKCE0.36911513
119ROCK20.35808061
120CSNK1G20.34788336
121PRKCB0.33642245
122MAP3K110.31727511
123JAK10.31473756
124PRKCA0.31059161
125BMX0.29185907
126MAPK80.27163215

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.63006854
2Synaptic vesicle cycle_Homo sapiens_hsa047213.16370403
3Olfactory transduction_Homo sapiens_hsa047402.84159625
4GABAergic synapse_Homo sapiens_hsa047272.73447190
5Circadian entrainment_Homo sapiens_hsa047132.69618370
6Long-term potentiation_Homo sapiens_hsa047202.67123894
7Glutamatergic synapse_Homo sapiens_hsa047242.65850303
8Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.60339178
9Morphine addiction_Homo sapiens_hsa050322.51867579
10Amphetamine addiction_Homo sapiens_hsa050312.41729060
11Salivary secretion_Homo sapiens_hsa049702.27191767
12Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049612.26074802
13Dopaminergic synapse_Homo sapiens_hsa047282.07936939
14Gastric acid secretion_Homo sapiens_hsa049711.99908508
15Insulin secretion_Homo sapiens_hsa049111.98430885
16Aldosterone synthesis and secretion_Homo sapiens_hsa049251.92863696
17Cholinergic synapse_Homo sapiens_hsa047251.92119974
18Taste transduction_Homo sapiens_hsa047421.75574427
19Nitrogen metabolism_Homo sapiens_hsa009101.74742989
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.73668401
21Long-term depression_Homo sapiens_hsa047301.72096000
22Oxytocin signaling pathway_Homo sapiens_hsa049211.66802832
23Cocaine addiction_Homo sapiens_hsa050301.65932989
24Calcium signaling pathway_Homo sapiens_hsa040201.63370579
25Renin secretion_Homo sapiens_hsa049241.62200642
26Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.53531021
27Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.50368854
28GnRH signaling pathway_Homo sapiens_hsa049121.48934640
29Serotonergic synapse_Homo sapiens_hsa047261.46732965
30Vitamin B6 metabolism_Homo sapiens_hsa007501.39781315
31cAMP signaling pathway_Homo sapiens_hsa040241.34097331
32Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.33260020
33Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.32484835
34Gap junction_Homo sapiens_hsa045401.30346949
35Phosphatidylinositol signaling system_Homo sapiens_hsa040701.28170085
36Type II diabetes mellitus_Homo sapiens_hsa049301.26056772
37Estrogen signaling pathway_Homo sapiens_hsa049151.14338663
38ECM-receptor interaction_Homo sapiens_hsa045121.09878100
39Glioma_Homo sapiens_hsa052141.08250595
40cGMP-PKG signaling pathway_Homo sapiens_hsa040221.03859441
41Collecting duct acid secretion_Homo sapiens_hsa049661.02660848
42Pancreatic secretion_Homo sapiens_hsa049720.99077723
43Phospholipase D signaling pathway_Homo sapiens_hsa040720.95964559
44Melanogenesis_Homo sapiens_hsa049160.95455481
45Cardiac muscle contraction_Homo sapiens_hsa042600.94503404
46ErbB signaling pathway_Homo sapiens_hsa040120.93912706
47Vascular smooth muscle contraction_Homo sapiens_hsa042700.93514495
48Focal adhesion_Homo sapiens_hsa045100.92155822
49Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.91594545
50Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.90845262
51Thyroid hormone synthesis_Homo sapiens_hsa049180.89385212
52Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.88827586
53Dorso-ventral axis formation_Homo sapiens_hsa043200.87553301
54Oocyte meiosis_Homo sapiens_hsa041140.84727111
55Axon guidance_Homo sapiens_hsa043600.82385583
56Dilated cardiomyopathy_Homo sapiens_hsa054140.78990697
57Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.75915927
58Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.75560826
59Carbohydrate digestion and absorption_Homo sapiens_hsa049730.74272009
60Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.73690380
61Choline metabolism in cancer_Homo sapiens_hsa052310.73610238
62Bile secretion_Homo sapiens_hsa049760.70339064
63MAPK signaling pathway_Homo sapiens_hsa040100.69856801
64Phototransduction_Homo sapiens_hsa047440.68972223
65Protein digestion and absorption_Homo sapiens_hsa049740.68391647
66AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.68127803
67Proteoglycans in cancer_Homo sapiens_hsa052050.64252321
68VEGF signaling pathway_Homo sapiens_hsa043700.63349640
69Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.63154192
70Glycosaminoglycan degradation_Homo sapiens_hsa005310.62091920
71Inositol phosphate metabolism_Homo sapiens_hsa005620.61647284
72Neurotrophin signaling pathway_Homo sapiens_hsa047220.61595327
73Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.61218468
74Thyroid hormone signaling pathway_Homo sapiens_hsa049190.59616831
75Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58326526
76Hippo signaling pathway_Homo sapiens_hsa043900.57985008
77Vibrio cholerae infection_Homo sapiens_hsa051100.57686841
78Rap1 signaling pathway_Homo sapiens_hsa040150.57264018
79Amoebiasis_Homo sapiens_hsa051460.57136878
80mTOR signaling pathway_Homo sapiens_hsa041500.56757354
81Glucagon signaling pathway_Homo sapiens_hsa049220.54170722
82Central carbon metabolism in cancer_Homo sapiens_hsa052300.53462131
83Sphingolipid signaling pathway_Homo sapiens_hsa040710.52005447
84Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.51870805
85Endocytosis_Homo sapiens_hsa041440.51595545
86Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.50802779
87Ras signaling pathway_Homo sapiens_hsa040140.50116681
88Type I diabetes mellitus_Homo sapiens_hsa049400.49728042
89Longevity regulating pathway - mammal_Homo sapiens_hsa042110.47240099
90Non-small cell lung cancer_Homo sapiens_hsa052230.46937902
91Circadian rhythm_Homo sapiens_hsa047100.46761893
92Regulation of actin cytoskeleton_Homo sapiens_hsa048100.45627657
93Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.45391474
94Alcoholism_Homo sapiens_hsa050340.43578196
95Ovarian steroidogenesis_Homo sapiens_hsa049130.42234595
96HIF-1 signaling pathway_Homo sapiens_hsa040660.41979758
97Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.41489783
98Chemokine signaling pathway_Homo sapiens_hsa040620.39330137
99Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.38737341
100Tight junction_Homo sapiens_hsa045300.38613545
101Arginine biosynthesis_Homo sapiens_hsa002200.38162324
102Chronic myeloid leukemia_Homo sapiens_hsa052200.37167609
103Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.36417474
104SNARE interactions in vesicular transport_Homo sapiens_hsa041300.35911174
105AMPK signaling pathway_Homo sapiens_hsa041520.35854333
106Insulin signaling pathway_Homo sapiens_hsa049100.34957162
107Glycerophospholipid metabolism_Homo sapiens_hsa005640.34840221
108Prion diseases_Homo sapiens_hsa050200.33752283
109Endometrial cancer_Homo sapiens_hsa052130.33484752
110African trypanosomiasis_Homo sapiens_hsa051430.32930834
111Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.32555378
112Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.32154409
113Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.31310866
114Renal cell carcinoma_Homo sapiens_hsa052110.30711132
115Wnt signaling pathway_Homo sapiens_hsa043100.30004511
116Platelet activation_Homo sapiens_hsa046110.26872527
117Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.26184372
118* Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.24905854

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