COA6

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the cytochrome c oxidase subunit 6B family. The encoded protein associates with cytochrome c oxidase may act has an cytochrome c oxidase mitochondrial respiratory complex VI assembly factor. Mutations in this gene may be associated with fatal infantile cardiomyopathy. Alternate splicing results in multiple transcript variants. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA deamination (GO:0045006)5.46653140
2proteasome assembly (GO:0043248)5.25422772
3mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.13942736
4ribosomal small subunit assembly (GO:0000028)4.84681592
5ATP synthesis coupled proton transport (GO:0015986)4.78105521
6energy coupled proton transport, down electrochemical gradient (GO:0015985)4.78105521
7mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.71603320
8ribosomal small subunit biogenesis (GO:0042274)4.61165268
9viral transcription (GO:0019083)4.50863896
10respiratory electron transport chain (GO:0022904)4.40511818
11translational termination (GO:0006415)4.39313929
12L-methionine biosynthetic process from methylthioadenosine (GO:0019509)4.31833201
13mitochondrial respiratory chain complex I assembly (GO:0032981)4.31657872
14NADH dehydrogenase complex assembly (GO:0010257)4.31657872
15mitochondrial respiratory chain complex I biogenesis (GO:0097031)4.31657872
16electron transport chain (GO:0022900)4.29072371
17exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 4.22167877
18cotranslational protein targeting to membrane (GO:0006613)4.20327803
19protein neddylation (GO:0045116)4.20016504
20amino acid salvage (GO:0043102)4.19839113
21L-methionine salvage (GO:0071267)4.19839113
22L-methionine biosynthetic process (GO:0071265)4.19839113
23SRP-dependent cotranslational protein targeting to membrane (GO:0006614)4.19803704
24chaperone-mediated protein transport (GO:0072321)4.19703263
25nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)4.15900983
26protein targeting to ER (GO:0045047)4.14080595
27chromatin remodeling at centromere (GO:0031055)4.14060294
28protein complex biogenesis (GO:0070271)4.10642593
29protein localization to endoplasmic reticulum (GO:0070972)4.07666485
30CENP-A containing nucleosome assembly (GO:0034080)4.07659002
31GTP biosynthetic process (GO:0006183)4.00369728
32translational elongation (GO:0006414)3.93472727
33mitochondrial respiratory chain complex assembly (GO:0033108)3.90116696
34establishment of protein localization to endoplasmic reticulum (GO:0072599)3.90106878
35erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.73873151
36L-phenylalanine metabolic process (GO:0006558)3.73873151
37establishment of protein localization to mitochondrial membrane (GO:0090151)3.73806741
38maturation of SSU-rRNA (GO:0030490)3.69244048
39rRNA processing (GO:0006364)3.67753888
40ATP biosynthetic process (GO:0006754)3.67559884
41guanosine-containing compound biosynthetic process (GO:1901070)3.65414965
42respiratory chain complex IV assembly (GO:0008535)3.64792336
43ribosomal large subunit biogenesis (GO:0042273)3.64200462
44regulation of mitochondrial translation (GO:0070129)3.62955041
45L-phenylalanine catabolic process (GO:0006559)3.62004755
46erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)3.62004755
47translation (GO:0006412)3.61677257
48transcription elongation from RNA polymerase III promoter (GO:0006385)3.61542292
49termination of RNA polymerase III transcription (GO:0006386)3.61542292
50spliceosomal snRNP assembly (GO:0000387)3.59711896
51water-soluble vitamin biosynthetic process (GO:0042364)3.58810390
52inner mitochondrial membrane organization (GO:0007007)3.57158531
53oxidative phosphorylation (GO:0006119)3.56486562
54regulation of cellular amino acid metabolic process (GO:0006521)3.56281379
55negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.55809739
56protein targeting to mitochondrion (GO:0006626)3.55008733
57rRNA metabolic process (GO:0016072)3.54818796
58viral life cycle (GO:0019058)3.53998594
59UTP biosynthetic process (GO:0006228)3.53331593
60DNA damage response, detection of DNA damage (GO:0042769)3.52483114
61establishment of protein localization to mitochondrion (GO:0072655)3.50499728
62protein deneddylation (GO:0000338)3.42899235
63translational initiation (GO:0006413)3.40138813
64cellular protein complex disassembly (GO:0043624)3.40126049
65metallo-sulfur cluster assembly (GO:0031163)3.40105446
66iron-sulfur cluster assembly (GO:0016226)3.40105446
67histone exchange (GO:0043486)3.37915279
68UTP metabolic process (GO:0046051)3.37433457
69pseudouridine synthesis (GO:0001522)3.37096657
70aldehyde catabolic process (GO:0046185)3.37005824
71serine family amino acid biosynthetic process (GO:0009070)3.34529616
72purine nucleobase biosynthetic process (GO:0009113)3.33774509
737-methylguanosine mRNA capping (GO:0006370)3.32236214
74intracellular protein transmembrane import (GO:0044743)3.29192466
75positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.29131079
76CTP metabolic process (GO:0046036)3.28116010
77CTP biosynthetic process (GO:0006241)3.28116010
78ribonucleoside triphosphate biosynthetic process (GO:0009201)3.27875639
797-methylguanosine RNA capping (GO:0009452)3.27702600
80RNA capping (GO:0036260)3.27702600
81mitochondrial transport (GO:0006839)3.27212286
82rRNA methylation (GO:0031167)3.27158751
83positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.27060543
84protein localization to mitochondrion (GO:0070585)3.26508814
85pyrimidine deoxyribonucleotide catabolic process (GO:0009223)3.25849982
86* hydrogen ion transmembrane transport (GO:1902600)3.25340019
87negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.25336183
88negative regulation of ligase activity (GO:0051352)3.25336183
89RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.25258700
90tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.25258700
91protein complex disassembly (GO:0043241)3.25214197
92cellular component biogenesis (GO:0044085)3.24333907
93cullin deneddylation (GO:0010388)3.24205423
94deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.23180225
95L-serine metabolic process (GO:0006563)3.22913742
96nuclear-transcribed mRNA catabolic process (GO:0000956)3.18671299
97maturation of 5.8S rRNA (GO:0000460)3.18328285
98methionine biosynthetic process (GO:0009086)3.17534730
99antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.17503267
100regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.16394522
101DNA replication checkpoint (GO:0000076)3.15653166
102macromolecular complex disassembly (GO:0032984)3.15620120
103positive regulation of ligase activity (GO:0051351)3.15277252
104GDP-mannose metabolic process (GO:0019673)3.14558174
105methionine metabolic process (GO:0006555)3.13172297
106signal transduction involved in DNA damage checkpoint (GO:0072422)3.12713846
107signal transduction involved in DNA integrity checkpoint (GO:0072401)3.12713846
108ribosome biogenesis (GO:0042254)3.12494269
109sulfur amino acid biosynthetic process (GO:0000097)3.11487135
110DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.11256813
111ribonucleoprotein complex biogenesis (GO:0022613)3.10843710
112nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184)3.10608167
113protein targeting to membrane (GO:0006612)3.10583630
114histone mRNA metabolic process (GO:0008334)3.10027145
115nucleobase biosynthetic process (GO:0046112)3.08963624
116signal transduction involved in cell cycle checkpoint (GO:0072395)3.07534938
117purine nucleoside triphosphate biosynthetic process (GO:0009145)3.06650021
118purine ribonucleoside monophosphate biosynthetic process (GO:0009168)3.04588591
119purine nucleoside monophosphate biosynthetic process (GO:0009127)3.04588591
120DNA replication-independent nucleosome organization (GO:0034724)3.04016677
121intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.03572611
122signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.03572611
123purine ribonucleoside triphosphate biosynthetic process (GO:0009206)3.03344587
124pyrimidine nucleoside triphosphate metabolic process (GO:0009147)3.01958950
125aromatic amino acid family catabolic process (GO:0009074)3.01843942
126cytochrome complex assembly (GO:0017004)3.01566243
127signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.01045232
128signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.01045232
129signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.01045232
130anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.00745744
131peptidyl-histidine modification (GO:0018202)2.99207799
132protein-cofactor linkage (GO:0018065)2.98793567
133pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)2.98438292
134rRNA modification (GO:0000154)2.95263781
135glycine metabolic process (GO:0006544)2.95107262
136antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.92480440
137deoxyribonucleoside triphosphate metabolic process (GO:0009200)2.92159793
138pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.91860352

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.60513822
2GABP_17652178_ChIP-ChIP_JURKAT_Human4.11457486
3JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.93420172
4SOX9_22984422_ChIP-ChIP_TESTIS_Rat3.90799303
5MYC_18555785_ChIP-Seq_MESCs_Mouse3.88053415
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.84728180
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.74005355
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.73204398
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.73103800
10ETS1_20019798_ChIP-Seq_JURKAT_Human3.54639696
11CREB1_15753290_ChIP-ChIP_HEK293T_Human3.31234282
12CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human3.26944125
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.02031413
14MYC_18358816_ChIP-ChIP_MESCs_Mouse3.00165494
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.90548580
16ESR1_17901129_ChIP-ChIP_LIVER_Mouse2.80544760
17VDR_23849224_ChIP-Seq_CD4+_Human2.67916138
18CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.66780824
19SRF_21415370_ChIP-Seq_HL-1_Mouse2.60723640
20PDX1_19855005_ChIP-ChIP_MIN6_Mouse2.54059480
21CEBPA_23403033_ChIP-Seq_LIVER_Mouse2.53760446
22MYC_19030024_ChIP-ChIP_MESCs_Mouse2.53050030
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.49214126
24E2F1_18555785_ChIP-Seq_MESCs_Mouse2.43317713
25DCP1A_22483619_ChIP-Seq_HELA_Human2.32737748
26MYC_19079543_ChIP-ChIP_MESCs_Mouse2.26989225
27THAP11_20581084_ChIP-Seq_MESCs_Mouse2.17155128
28XRN2_22483619_ChIP-Seq_HELA_Human2.15956599
29CEBPB_23403033_ChIP-Seq_LIVER_Mouse2.13210672
30* EGR1_23403033_ChIP-Seq_LIVER_Mouse2.11013446
31FOXP3_21729870_ChIP-Seq_TREG_Human2.08827976
32GABP_19822575_ChIP-Seq_HepG2_Human1.95491770
33YY1_21170310_ChIP-Seq_MESCs_Mouse1.93827435
34* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.89355675
35FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.88775318
36NELFA_20434984_ChIP-Seq_ESCs_Mouse1.86145118
37CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.84548931
38SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.83869665
39ELK1_19687146_ChIP-ChIP_HELA_Human1.81486761
40E2F7_22180533_ChIP-Seq_HELA_Human1.79629201
41FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.79600318
42HOXB4_20404135_ChIP-ChIP_EML_Mouse1.73833562
43ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.73697547
44TTF2_22483619_ChIP-Seq_HELA_Human1.69816900
45PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.64286799
46PPARG_19300518_ChIP-PET_3T3-L1_Mouse1.62340157
47TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.62252947
48ERG_20887958_ChIP-Seq_HPC-7_Mouse1.57647891
49E2F4_17652178_ChIP-ChIP_JURKAT_Human1.55951053
50RXR_22158963_ChIP-Seq_LIVER_Mouse1.52103705
51FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.51370690
52PPARA_22158963_ChIP-Seq_LIVER_Mouse1.47878516
53HNF4A_19761587_ChIP-ChIP_CACO-2_Human1.47464511
54FOXM1_23109430_ChIP-Seq_U2OS_Human1.43426643
55POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.41354727
56E2F1_21310950_ChIP-Seq_MCF-7_Human1.39690944
57ZFX_18555785_ChIP-Seq_MESCs_Mouse1.36661663
58MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.32377746
59NOTCH1_21737748_ChIP-Seq_TLL_Human1.30659175
60MYCN_18555785_ChIP-Seq_MESCs_Mouse1.26262709
61EWS_26573619_Chip-Seq_HEK293_Human1.25972347
62ELK1_22589737_ChIP-Seq_MCF10A_Human1.25792651
63BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.25559490
64MYC_18940864_ChIP-ChIP_HL60_Human1.20784599
65POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.19064616
66NANOG_18555785_ChIP-Seq_MESCs_Mouse1.16548005
67SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.15581615
68ESRRB_18555785_ChIP-Seq_MESCs_Mouse1.12960543
69MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.12279817
70CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human1.09533716
71MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.09152255
72ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09012362
73CTCF_18555785_ChIP-Seq_MESCs_Mouse1.08220417
74NANOG_16153702_ChIP-ChIP_HESCs_Human1.07543903
75YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.06268665
76AR_21909140_ChIP-Seq_LNCAP_Human1.05817258
77TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.03619640
78ZNF274_21170338_ChIP-Seq_K562_Hela1.03122621
79HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.02873317
80CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.01938362
81VDR_22108803_ChIP-Seq_LS180_Human1.01149044
82SOX2_18555785_ChIP-Seq_MESCs_Mouse1.00394325
83FUS_26573619_Chip-Seq_HEK293_Human0.99560644
84IRF1_19129219_ChIP-ChIP_H3396_Human0.99503167
85DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.99452995
86FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.98743472
87SOX2_16153702_ChIP-ChIP_HESCs_Human0.97580151
88TP63_19390658_ChIP-ChIP_HaCaT_Human0.94962237
89SRY_22984422_ChIP-ChIP_TESTIS_Rat0.94922756
90POU5F1_16153702_ChIP-ChIP_HESCs_Human0.93760304
91SPI1_22096565_ChIP-ChIP_GC-B_Mouse0.93195610
92PADI4_21655091_ChIP-ChIP_MCF-7_Human0.92784989
93CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.92017741
94GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.90809361
95STAT3_1855785_ChIP-Seq_MESCs_Mouse0.90809270
96TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.90456666
97KDM5A_27292631_Chip-Seq_BREAST_Human0.85607271
98IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.85120331
99SPI1_23547873_ChIP-Seq_NB4_Human0.84918220
100SOX17_20123909_ChIP-Seq_XEN_Mouse0.80079740
101RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.79466218
102KDM5B_21448134_ChIP-Seq_MESCs_Mouse0.77913286
103HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.77891183
104POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.77698037
105FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.77369780
106EBNA2_21746931_ChIP-Seq_IB4-LCL_Human0.77048266
107E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.76061106
108TP53_22573176_ChIP-Seq_HFKS_Human0.75496663
109TBX5_21415370_ChIP-Seq_HL-1_Mouse0.74444647
110KAP1_22055183_ChIP-Seq_ESCs_Mouse0.73873484
111SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.72689402
112SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.72378460
113NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.71685992
114LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.71577537
115GATA1_22383799_ChIP-Seq_G1ME_Mouse0.70902258
116KLF4_19030024_ChIP-ChIP_MESCs_Mouse0.70686132
117SIN3A_21632747_ChIP-Seq_MESCs_Mouse0.70214422
118TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.68443670
119CIITA_25753668_ChIP-Seq_RAJI_Human0.68369048
120MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.66106080
121FOXP1_21924763_ChIP-Seq_HESCs_Human0.65435054
122ELF5_23300383_ChIP-Seq_T47D_Human0.65044623

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003806_abnormal_nucleotide_metabolis5.45343975
2MP0005360_urolithiasis4.05336501
3MP0002139_abnormal_hepatobiliary_system4.05266386
4MP0005085_abnormal_gallbladder_physiolo3.69388240
5MP0009379_abnormal_foot_pigmentation3.53485023
6MP0008875_abnormal_xenobiotic_pharmacok3.30490612
7MP0005365_abnormal_bile_salt3.27606112
8MP0003186_abnormal_redox_activity3.02513458
9MP0004147_increased_porphyrin_level2.94324399
10MP0006036_abnormal_mitochondrial_physio2.92742379
11MP0005332_abnormal_amino_acid2.68633883
12MP0000372_irregular_coat_pigmentation2.61478779
13MP0003195_calcinosis2.53664806
14MP0005083_abnormal_biliary_tract2.48233774
15MP0003693_abnormal_embryo_hatching2.43641971
16MP0001529_abnormal_vocalization2.40418283
17MP0002132_abnormal_respiratory_system2.28091466
18MP0001764_abnormal_homeostasis2.24607464
19MP0003941_abnormal_skin_development2.14259521
20MP0006035_abnormal_mitochondrial_morpho2.13632525
21MP0003718_maternal_effect2.01744519
22MP0004957_abnormal_blastocyst_morpholog2.00864999
23MP0002277_abnormal_respiratory_mucosa2.00586204
24MP0009697_abnormal_copulation1.95466881
25MP0001666_abnormal_nutrient_absorption1.81462604
26MP0005636_abnormal_mineral_homeostasis1.79634117
27MP0001293_anophthalmia1.77107983
28MP0003656_abnormal_erythrocyte_physiolo1.75323946
29MP0005084_abnormal_gallbladder_morpholo1.73707497
30MP0009840_abnormal_foam_cell1.73204063
31MP0006072_abnormal_retinal_apoptosis1.65405174
32MP0005451_abnormal_body_composition1.63690367
33MP0004142_abnormal_muscle_tone1.60949156
34MP0008932_abnormal_embryonic_tissue1.60631018
35MP0005075_abnormal_melanosome_morpholog1.56994695
36MP0003136_yellow_coat_color1.55627267
37MP0005408_hypopigmentation1.51437141
38MP0005584_abnormal_enzyme/coenzyme_acti1.46660427
39MP0004019_abnormal_vitamin_homeostasis1.46089900
40MP0002638_abnormal_pupillary_reflex1.43781216
41MP0003724_increased_susceptibility_to1.42346532
42MP0004381_abnormal_hair_follicle1.42272267
43MP0001905_abnormal_dopamine_level1.37167539
44MP0010329_abnormal_lipoprotein_level1.34130173
45MP0001485_abnormal_pinna_reflex1.33618681
46MP0000049_abnormal_middle_ear1.32100047
47MP0008789_abnormal_olfactory_epithelium1.29551546
48MP0009643_abnormal_urine_homeostasis1.27858885
49MP0003111_abnormal_nucleus_morphology1.27420805
50MP0000631_abnormal_neuroendocrine_gland1.26493156
51MP0010030_abnormal_orbit_morphology1.25796642
52MP0009785_altered_susceptibility_to1.25179624
53MP0008058_abnormal_DNA_repair1.24027478
54MP0005319_abnormal_enzyme/_coenzyme1.22811885
55MP0010094_abnormal_chromosome_stability1.21197668
56MP0002210_abnormal_sex_determination1.17730797
57MP0005379_endocrine/exocrine_gland_phen1.17144383
58MP0002102_abnormal_ear_morphology1.16695528
59MP0003077_abnormal_cell_cycle1.15670319
60MP0003786_premature_aging1.15552145
61MP0003567_abnormal_fetal_cardiomyocyte1.12495337
62MP0002876_abnormal_thyroid_physiology1.11687127
63MP0004145_abnormal_muscle_electrophysio1.11001417
64MP0001986_abnormal_taste_sensitivity1.10762740
65MP0002095_abnormal_skin_pigmentation1.08807306
66MP0001188_hyperpigmentation1.07098232
67MP0001919_abnormal_reproductive_system1.04878437
68MP0003646_muscle_fatigue1.04513610
69MP0003011_delayed_dark_adaptation1.03002524
70MP0008469_abnormal_protein_level0.99241994
71MP0002396_abnormal_hematopoietic_system0.99112959
72MP0001145_abnormal_male_reproductive0.97976136
73MP0001853_heart_inflammation0.97639876
74MP0005174_abnormal_tail_pigmentation0.97433657
75MP0001929_abnormal_gametogenesis0.97031950
76MP0000358_abnormal_cell_content/0.96854590
77MP0009333_abnormal_splenocyte_physiolog0.95686582
78MP0002163_abnormal_gland_morphology0.95386877
79MP0005253_abnormal_eye_physiology0.94197182
80MP0000653_abnormal_sex_gland0.94102300
81MP0002118_abnormal_lipid_homeostasis0.93231266
82MP0008260_abnormal_autophagy0.92807364
83MP0002653_abnormal_ependyma_morphology0.92464595
84MP0008995_early_reproductive_senescence0.91853765
85MP0005646_abnormal_pituitary_gland0.91600955
86MP0002090_abnormal_vision0.91139659
87MP0006292_abnormal_olfactory_placode0.90949371
88MP0000350_abnormal_cell_proliferation0.89234091
89MP0009046_muscle_twitch0.89194600
90MP0003123_paternal_imprinting0.88167314
91MP0001697_abnormal_embryo_size0.87706498
92MP0003868_abnormal_feces_composition0.87214320
93MP0004215_abnormal_myocardial_fiber0.87144498
94MP0000609_abnormal_liver_physiology0.85972257
95MP0002234_abnormal_pharynx_morphology0.85939469
96MP0002837_dystrophic_cardiac_calcinosis0.85793995
97MP0005266_abnormal_metabolism0.85773742
98MP0005376_homeostasis/metabolism_phenot0.85189160
99MP0003937_abnormal_limbs/digits/tail_de0.84647535
100MP0006276_abnormal_autonomic_nervous0.83574417
101MP0008007_abnormal_cellular_replicative0.83486913
102MP0005410_abnormal_fertilization0.83176954
103MP0003880_abnormal_central_pattern0.82983160
104MP0005551_abnormal_eye_electrophysiolog0.82413707
105MP0001286_abnormal_eye_development0.79614613
106MP0004043_abnormal_pH_regulation0.79333109
107MP0005671_abnormal_response_to0.79001642
108MP0005220_abnormal_exocrine_pancreas0.78265418
109MP0001881_abnormal_mammary_gland0.78017503
110MP0003191_abnormal_cellular_cholesterol0.77536677
111MP0000313_abnormal_cell_death0.76747694
112MP0001324_abnormal_eye_pigmentation0.76600260
113MP0003315_abnormal_perineum_morphology0.76468665
114MP0003137_abnormal_impulse_conducting0.76466693
115MP0004133_heterotaxia0.76412949
116MP0000598_abnormal_liver_morphology0.76038236
117MP0002233_abnormal_nose_morphology0.75415312
118MP0000689_abnormal_spleen_morphology0.75093736
119MP0008877_abnormal_DNA_methylation0.74639888
120MP0002697_abnormal_eye_size0.73934158
121MP0001542_abnormal_bone_strength0.73289266
122MP0008057_abnormal_DNA_replication0.72461708
123MP0009764_decreased_sensitivity_to0.72445800
124MP0003938_abnormal_ear_development0.71632618
125MP0000490_abnormal_crypts_of0.71203810
126MP0009642_abnormal_blood_homeostasis0.68791999
127MP0001730_embryonic_growth_arrest0.68436490
128MP0005025_abnormal_response_to0.67929515
129MP0009765_abnormal_xenobiotic_induced0.67533545
130MP0000749_muscle_degeneration0.66587523
131MP0009250_abnormal_appendicular_skeleto0.65726509
132MP0008872_abnormal_physiological_respon0.64046093
133MP0005394_taste/olfaction_phenotype0.63718275
134MP0005499_abnormal_olfactory_system0.63718275
135MP0010386_abnormal_urinary_bladder0.63692958
136MP0001119_abnormal_female_reproductive0.63228054
137MP0001756_abnormal_urination0.62842323
138MP0002160_abnormal_reproductive_system0.62576837
139MP0000647_abnormal_sebaceous_gland0.62030432
140MP0003763_abnormal_thymus_physiology0.61245643
141MP0002148_abnormal_hypersensitivity_rea0.60465153
142MP0002019_abnormal_tumor_incidence0.59289108
143MP0008873_increased_physiological_sensi0.59082433
144MP0009763_increased_sensitivity_to0.58795978
145MP0003638_abnormal_response/metabolism_0.58597736
146MP0002722_abnormal_immune_system0.57860294
147MP0002736_abnormal_nociception_after0.57753643
148MP0005395_other_phenotype0.55446687
149MP0004782_abnormal_surfactant_physiolog0.54879047
150MP0000681_abnormal_thyroid_gland0.52988312
151MP0005409_darkened_coat_color0.51682059
152MP0005389_reproductive_system_phenotype0.51068046
153MP0001984_abnormal_olfaction0.51057432
154MP0002938_white_spotting0.50762225
155MP0001845_abnormal_inflammatory_respons0.50395433

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)4.92479686
2Mitochondrial inheritance (HP:0001427)4.73406000
3Abnormal mitochondria in muscle tissue (HP:0008316)4.63448776
4Acute encephalopathy (HP:0006846)4.58144611
5Hepatocellular necrosis (HP:0001404)4.49736096
63-Methylglutaconic aciduria (HP:0003535)4.44393079
7Hepatic necrosis (HP:0002605)4.42155302
8Abnormal activity of mitochondrial respiratory chain (HP:0011922)4.38084594
9Decreased activity of mitochondrial respiratory chain (HP:0008972)4.38084594
10Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)4.35485778
11Increased hepatocellular lipid droplets (HP:0006565)4.33626141
12Increased CSF lactate (HP:0002490)4.23528294
13Lipid accumulation in hepatocytes (HP:0006561)4.23174614
14Abnormality of aromatic amino acid family metabolism (HP:0004338)4.12959420
15Progressive macrocephaly (HP:0004481)4.00116999
16Muscle abnormality related to mitochondrial dysfunction (HP:0003800)3.99913458
17Renal Fanconi syndrome (HP:0001994)3.87386219
18Cerebral edema (HP:0002181)3.85713020
19Increased intramyocellular lipid droplets (HP:0012240)3.80723382
20Abnormality of cells of the erythroid lineage (HP:0012130)3.80292069
21Increased serum lactate (HP:0002151)3.70158935
22Abnormal number of erythroid precursors (HP:0012131)3.57926171
23Lactic acidosis (HP:0003128)3.51541168
24Increased muscle lipid content (HP:0009058)3.46943514
25Increased serum pyruvate (HP:0003542)3.13030877
26Abnormality of glycolysis (HP:0004366)3.13030877
27Macrocytic anemia (HP:0001972)3.12637637
28Exercise intolerance (HP:0003546)3.11657371
29Exertional dyspnea (HP:0002875)3.09992094
30Hypobetalipoproteinemia (HP:0003563)3.08879924
31Lethargy (HP:0001254)3.07241434
32Respiratory failure (HP:0002878)2.98629760
33Abnormality of urine glucose concentration (HP:0011016)2.88153055
34Glycosuria (HP:0003076)2.88153055
35Reticulocytopenia (HP:0001896)2.82551401
36Abnormality of renal resorption (HP:0011038)2.81886886
37Respiratory difficulties (HP:0002880)2.81068221
38Abnormality of dicarboxylic acid metabolism (HP:0010995)2.71325942
39Dicarboxylic aciduria (HP:0003215)2.71325942
40Methylmalonic acidemia (HP:0002912)2.71230824
41Hyperglycinemia (HP:0002154)2.67438827
42Generalized aminoaciduria (HP:0002909)2.64964917
43CNS demyelination (HP:0007305)2.63921362
44Congenital, generalized hypertrichosis (HP:0004540)2.63641138
45Prolonged partial thromboplastin time (HP:0003645)2.60752512
46Leukodystrophy (HP:0002415)2.59866739
47Abnormality of the heme biosynthetic pathway (HP:0010472)2.53821923
48Abnormality of monocarboxylic acid metabolism (HP:0010996)2.50888920
49Hyperammonemia (HP:0001987)2.50608453
50Abnormality of fatty-acid metabolism (HP:0004359)2.49266339
51Abnormality of glycine metabolism (HP:0010895)2.46319746
52Abnormality of serine family amino acid metabolism (HP:0010894)2.46319746
53Hyperphosphaturia (HP:0003109)2.46155361
54Abnormality of serum amino acid levels (HP:0003112)2.45438765
55Type I transferrin isoform profile (HP:0003642)2.42813519
56Hyperglycinuria (HP:0003108)2.37652298
57Intrahepatic cholestasis (HP:0001406)2.34471745
58Optic disc pallor (HP:0000543)2.34079214
59Cerebral hypomyelination (HP:0006808)2.26693738
60Delayed CNS myelination (HP:0002188)2.25953016
61Abnormality of methionine metabolism (HP:0010901)2.22760528
62Microvesicular hepatic steatosis (HP:0001414)2.22721712
63Hyperlipoproteinemia (HP:0010980)2.19859878
64Pallor (HP:0000980)2.19684165
65Abnormality of pyrimidine metabolism (HP:0004353)2.19587409
66Aplasia/Hypoplasia of the sacrum (HP:0008517)2.19206816
67Nausea (HP:0002018)2.18920246
68Reduced antithrombin III activity (HP:0001976)2.17441285
69Septo-optic dysplasia (HP:0100842)2.17370888
70Abnormality of aspartate family amino acid metabolism (HP:0010899)2.15172132
71Meckel diverticulum (HP:0002245)2.14824627
72Vomiting (HP:0002013)2.13742033
73Abnormality of the anterior horn cell (HP:0006802)2.11139324
74Degeneration of anterior horn cells (HP:0002398)2.11139324
75Cleft eyelid (HP:0000625)2.11022681
76Aplastic anemia (HP:0001915)2.09878040
77Methylmalonic aciduria (HP:0012120)2.08739277
78Colon cancer (HP:0003003)2.08609603
79Pancreatic fibrosis (HP:0100732)2.07495108
80Pancreatic cysts (HP:0001737)2.04374612
81Microretrognathia (HP:0000308)2.02942406
82Oral leukoplakia (HP:0002745)2.02228731
83Abnormality of the ileum (HP:0001549)2.01624213
84Ketosis (HP:0001946)2.01006759
85Metabolic acidosis (HP:0001942)2.00805068
86Aplasia/hypoplasia of the uterus (HP:0008684)1.99437088
87Absent thumb (HP:0009777)1.99086486
88Megaloblastic anemia (HP:0001889)1.98888115
89Brushfield spots (HP:0001088)1.98742307
90Abnormal pupillary function (HP:0007686)1.98588863
91X-linked dominant inheritance (HP:0001423)1.98240569
92Hypoglycemic coma (HP:0001325)1.96656295
93Emotional lability (HP:0000712)1.96252064
94Abnormality of long-chain fatty-acid metabolism (HP:0010964)1.96138130
95Abnormality of the pons (HP:0007361)1.96075804
96Aplasia/Hypoplasia of the uvula (HP:0010293)1.94224692
97Abnormality of alanine metabolism (HP:0010916)1.93967782
98Hyperalaninemia (HP:0003348)1.93967782
99Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.93967782
100Congenital nonbullous ichthyosiform erythroderma (HP:0007479)1.93564581
101Pancytopenia (HP:0001876)1.93384039
102Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.92825626
103Abnormal protein glycosylation (HP:0012346)1.92825626
104Abnormality of the preputium (HP:0100587)1.92544756
105Progressive external ophthalmoplegia (HP:0000590)1.92371660
106Pendular nystagmus (HP:0012043)1.92293977
107Hypoplasia of the pons (HP:0012110)1.92098707
108Abnormality of midbrain morphology (HP:0002418)1.90817418
109Molar tooth sign on MRI (HP:0002419)1.90817418
110Xanthomatosis (HP:0000991)1.89685535
111Sparse eyelashes (HP:0000653)1.85873418
112Hyperbilirubinemia (HP:0002904)1.85194300
113True hermaphroditism (HP:0010459)1.83899159
114Rough bone trabeculation (HP:0100670)1.82408835
115Delayed myelination (HP:0012448)1.81786930
116Petechiae (HP:0000967)1.80984761
117Proximal tubulopathy (HP:0000114)1.79868997
118Birth length less than 3rd percentile (HP:0003561)1.79416980
119Triphalangeal thumb (HP:0001199)1.79363182
120Abnormal urine phosphate concentration (HP:0012599)1.78636471
121Abnormality of chromosome stability (HP:0003220)1.77581449
122Renal tubular dysfunction (HP:0000124)1.77281477
123Secondary amenorrhea (HP:0000869)1.77143668
124Blindness (HP:0000618)1.76963002
125Sclerocornea (HP:0000647)1.76509450
126Abnormality of secondary sexual hair (HP:0009888)1.75291919
127Abnormality of the axillary hair (HP:0100134)1.75291919
128Abnormal protein N-linked glycosylation (HP:0012347)1.74595221
129Abnormal glycosylation (HP:0012345)1.74595221
130Testicular atrophy (HP:0000029)1.71630541
131Homocystinuria (HP:0002156)1.71257484
132Abnormality of homocysteine metabolism (HP:0010919)1.71257484
133Severe visual impairment (HP:0001141)1.64904915
134Chromosomal breakage induced by crosslinking agents (HP:0003221)1.63925312
135Abnormal lung lobation (HP:0002101)1.62672697

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.95501034
2STK164.65958239
3NME24.51908078
4VRK23.99593130
5BCKDK3.76811624
6WEE12.78354854
7NME12.76364645
8EIF2AK12.65005501
9NEK12.32917735
10VRK12.11080492
11EIF2AK31.87969833
12TIE11.79842185
13TLK11.79457608
14ARAF1.78936047
15PIM21.75606209
16NUAK11.73784639
17CDK81.73181020
18KDR1.61739561
19TESK21.61273639
20TSSK61.59380111
21MAP3K121.58036736
22IRAK11.55471472
23CCNB11.54323290
24IRAK41.54037628
25PDK21.52597725
26DYRK31.52123351
27TRIM281.50428704
28PLK41.49809211
29BRAF1.47569105
30IRAK31.46105777
31TAF11.42130893
32MAP4K21.41176809
33MST41.38328836
34SRPK11.36312972
35ACVR1B1.30778111
36CASK1.27027626
37BRSK21.23300267
38MYLK1.18618716
39TEC1.11069761
40ABL21.08059374
41CDK191.07596872
42MAPKAPK51.03268157
43OXSR11.01138850
44CHEK20.99908920
45AURKA0.97576826
46STK40.92767859
47IRAK20.88377347
48MAPK150.84439151
49INSRR0.84057487
50WNK40.81878443
51CSNK1G20.81529035
52MKNK10.79202091
53PLK10.76676456
54RPS6KA50.76549062
55CSNK2A10.75878693
56LIMK10.75627781
57CSNK1G30.73647377
58MAP3K110.72671553
59PINK10.72305042
60PBK0.70273730
61DYRK20.69105972
62RPS6KA40.68948688
63MAP2K70.67811655
64ADRBK20.66644370
65CDC70.66576245
66CAMK2G0.66372303
67CSNK2A20.65665362
68ZAK0.64235177
69FLT30.62931377
70STK390.62761611
71AURKB0.62170364
72MUSK0.61498879
73STK30.59410316
74PASK0.58049313
75STK240.57479979
76KIT0.57087683
77MAPKAPK30.56358359
78CDK30.56011867
79CHEK10.55645719
80TESK10.52874343
81ATM0.52821621
82CSNK1G10.52074685
83MAP4K10.52059506
84OBSCN0.51962504
85PRKCG0.51073526
86CSNK1E0.50378445
87DAPK30.49929554
88GRK70.49890257
89TXK0.49299895
90AKT30.48751180
91RPS6KB20.48332069
92PLK20.48172655
93CSNK1A1L0.47691848
94EIF2AK20.47422930
95ZAP700.46909963
96CAMK2B0.46491525
97PLK30.46424236
98BCR0.45235108
99MAP3K90.44634960
100MKNK20.43686722
101ILK0.43522654
102BMPR1B0.43442225
103MAPK40.42763781
104NEK20.42691728
105BTK0.42514035
106CSNK1A10.41887633
107DAPK10.40458344
108CDK70.40418007
109MAP2K60.39791208
110GRK10.39601007
111TNIK0.39115367
112NEK90.38927974
113LYN0.38808267
114PNCK0.37652917
115PAK10.37546195
116GRK50.36875171
117PIK3CG0.36478975
118TGFBR10.36458186
119ERBB30.36010777
120BRSK10.34685781
121CAMKK20.34282797
122WNK30.34025883
123MAP3K40.33699494
124PAK40.31016094
125ATR0.30754039
126ALK0.30727840
127MAP3K80.30657340
128TTK0.30404034
129PRKCI0.30085632
130BMPR20.29645164
131FRK0.29196675
132CDK10.28302787
133AKT20.25923180
134CDK20.24308201
135ERBB40.23523004

Predicted pathways (KEGG)

RankGene SetZ-score
1Ribosome_Homo sapiens_hsa030103.92167116
2Proteasome_Homo sapiens_hsa030503.49958123
3Oxidative phosphorylation_Homo sapiens_hsa001903.41206786
4Parkinsons disease_Homo sapiens_hsa050122.96611670
5RNA polymerase_Homo sapiens_hsa030202.80060046
6Protein export_Homo sapiens_hsa030602.63217783
7Huntingtons disease_Homo sapiens_hsa050162.17895248
8Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001302.15156703
9Folate biosynthesis_Homo sapiens_hsa007902.12101899
10DNA replication_Homo sapiens_hsa030302.11811053
11Pyrimidine metabolism_Homo sapiens_hsa002402.08091187
12Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.03073076
13Alzheimers disease_Homo sapiens_hsa050101.97981374
14Primary bile acid biosynthesis_Homo sapiens_hsa001201.96691597
15Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.90933017
16Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.88483520
17Sulfur metabolism_Homo sapiens_hsa009201.66650584
18Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.64818946
19Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.64178760
20Mismatch repair_Homo sapiens_hsa034301.62839271
21Peroxisome_Homo sapiens_hsa041461.59674030
22Fatty acid elongation_Homo sapiens_hsa000621.58213463
23Sulfur relay system_Homo sapiens_hsa041221.51322027
24Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.51264537
25Vitamin B6 metabolism_Homo sapiens_hsa007501.49960721
26Drug metabolism - other enzymes_Homo sapiens_hsa009831.49168989
27Cysteine and methionine metabolism_Homo sapiens_hsa002701.48094491
28Nucleotide excision repair_Homo sapiens_hsa034201.44842190
29Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.41831990
30Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.34160491
31Glutathione metabolism_Homo sapiens_hsa004801.33906344
32Homologous recombination_Homo sapiens_hsa034401.32793642
33Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.29750144
34Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.29549981
35Base excision repair_Homo sapiens_hsa034101.29464142
36Propanoate metabolism_Homo sapiens_hsa006401.25303487
37Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.22600354
38Pyruvate metabolism_Homo sapiens_hsa006201.22451263
39Spliceosome_Homo sapiens_hsa030401.20405736
40One carbon pool by folate_Homo sapiens_hsa006701.18039499
41Butanoate metabolism_Homo sapiens_hsa006501.17629670
422-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.17145766
43Purine metabolism_Homo sapiens_hsa002301.14983719
44Chemical carcinogenesis_Homo sapiens_hsa052041.14904369
45Carbon metabolism_Homo sapiens_hsa012001.13233834
46Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.12044283
47Pentose and glucuronate interconversions_Homo sapiens_hsa000401.11392929
48Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.09979566
49Fatty acid degradation_Homo sapiens_hsa000711.07435907
50Biosynthesis of amino acids_Homo sapiens_hsa012301.07188154
51Arginine and proline metabolism_Homo sapiens_hsa003301.05671831
52Cyanoamino acid metabolism_Homo sapiens_hsa004601.04873702
53Histidine metabolism_Homo sapiens_hsa003401.04450425
54Tryptophan metabolism_Homo sapiens_hsa003801.01240384
55Metabolic pathways_Homo sapiens_hsa011000.99643879
56Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.99470336
57Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.98652608
58beta-Alanine metabolism_Homo sapiens_hsa004100.98009499
59Pentose phosphate pathway_Homo sapiens_hsa000300.96666595
60Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.96533591
61Phenylalanine metabolism_Homo sapiens_hsa003600.96160512
62RNA transport_Homo sapiens_hsa030130.94302636
63Basal transcription factors_Homo sapiens_hsa030220.93725087
64Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.93352284
65Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.92501018
66Selenocompound metabolism_Homo sapiens_hsa004500.91831387
67Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.88598640
68Caffeine metabolism_Homo sapiens_hsa002320.86639679
69Steroid hormone biosynthesis_Homo sapiens_hsa001400.82226370
70Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.81874695
71Tyrosine metabolism_Homo sapiens_hsa003500.81419883
72Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.79505667
73Cardiac muscle contraction_Homo sapiens_hsa042600.78859954
74Arginine biosynthesis_Homo sapiens_hsa002200.77870502
75RNA degradation_Homo sapiens_hsa030180.72573554
76Non-homologous end-joining_Homo sapiens_hsa034500.68381043
77SNARE interactions in vesicular transport_Homo sapiens_hsa041300.68255078
78Steroid biosynthesis_Homo sapiens_hsa001000.67962617
79Fructose and mannose metabolism_Homo sapiens_hsa000510.66991027
80Fatty acid metabolism_Homo sapiens_hsa012120.66538611
81Retinol metabolism_Homo sapiens_hsa008300.61690884
82Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.58638244
83Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.57544968
84Complement and coagulation cascades_Homo sapiens_hsa046100.57369184
85Regulation of autophagy_Homo sapiens_hsa041400.55926856
86Galactose metabolism_Homo sapiens_hsa000520.52285498
87PPAR signaling pathway_Homo sapiens_hsa033200.49337041
88Maturity onset diabetes of the young_Homo sapiens_hsa049500.44636235
89Arachidonic acid metabolism_Homo sapiens_hsa005900.44162954
90mRNA surveillance pathway_Homo sapiens_hsa030150.43532914
91p53 signaling pathway_Homo sapiens_hsa041150.41277942
92Phototransduction_Homo sapiens_hsa047440.40052996
93Collecting duct acid secretion_Homo sapiens_hsa049660.39561188
94Nitrogen metabolism_Homo sapiens_hsa009100.38089804
95Starch and sucrose metabolism_Homo sapiens_hsa005000.37552114
96Vitamin digestion and absorption_Homo sapiens_hsa049770.37222659
97Fanconi anemia pathway_Homo sapiens_hsa034600.35398383
98Cell cycle_Homo sapiens_hsa041100.34906261
99Oocyte meiosis_Homo sapiens_hsa041140.34467013
100Other glycan degradation_Homo sapiens_hsa005110.31606366
101Fat digestion and absorption_Homo sapiens_hsa049750.29619523
102Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.29277259
103Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.28148416
104Systemic lupus erythematosus_Homo sapiens_hsa053220.26308225
105Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.23901495
106Epstein-Barr virus infection_Homo sapiens_hsa051690.20763680
107Linoleic acid metabolism_Homo sapiens_hsa005910.17644149
108Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.17091745
109N-Glycan biosynthesis_Homo sapiens_hsa005100.15367233
110Primary immunodeficiency_Homo sapiens_hsa053400.13369420
111Basal cell carcinoma_Homo sapiens_hsa052170.07544131

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