COA7

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1proteasome assembly (GO:0043248)5.30722737
2termination of RNA polymerase III transcription (GO:0006386)4.68975555
3transcription elongation from RNA polymerase III promoter (GO:0006385)4.68975555
4purine nucleobase biosynthetic process (GO:0009113)4.51266192
5DNA deamination (GO:0045006)4.47956903
6rRNA modification (GO:0000154)4.22587381
7spliceosomal snRNP assembly (GO:0000387)4.21368641
8nucleobase biosynthetic process (GO:0046112)4.18828485
9regulation of mitochondrial translation (GO:0070129)4.15649840
10transcription elongation from RNA polymerase I promoter (GO:0006362)4.10788335
117-methylguanosine mRNA capping (GO:0006370)4.09711148
127-methylguanosine RNA capping (GO:0009452)4.08507648
13RNA capping (GO:0036260)4.08507648
14termination of RNA polymerase I transcription (GO:0006363)4.05338245
15maturation of SSU-rRNA (GO:0030490)3.93061601
16ribosome biogenesis (GO:0042254)3.85284890
17negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.83165565
18transcription from RNA polymerase I promoter (GO:0006360)3.81349724
19spliceosomal complex assembly (GO:0000245)3.72537586
20cullin deneddylation (GO:0010388)3.70991552
21positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.69300288
22ribosomal large subunit biogenesis (GO:0042273)3.68447500
23deoxyribonucleoside monophosphate metabolic process (GO:0009162)3.68441758
24mitochondrial RNA metabolic process (GO:0000959)3.67969158
25DNA replication checkpoint (GO:0000076)3.67045777
26nuclear pore complex assembly (GO:0051292)3.66993589
27transcription-coupled nucleotide-excision repair (GO:0006283)3.66837902
28nuclear pore organization (GO:0006999)3.64977330
29regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.63604743
30anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.63172688
31ribonucleoprotein complex biogenesis (GO:0022613)3.60560413
32mitotic metaphase plate congression (GO:0007080)3.57669112
33kinetochore assembly (GO:0051382)3.55409300
34DNA unwinding involved in DNA replication (GO:0006268)3.52814916
35telomere maintenance via semi-conservative replication (GO:0032201)3.47730645
36regulation of nuclear cell cycle DNA replication (GO:0033262)3.45944246
37negative regulation of ligase activity (GO:0051352)3.45658775
38negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.45658775
39protein deneddylation (GO:0000338)3.45025789
40pseudouridine synthesis (GO:0001522)3.44311053
41mitochondrial ATP synthesis coupled proton transport (GO:0042776)3.43961478
42rRNA methylation (GO:0031167)3.42786344
43DNA strand elongation involved in DNA replication (GO:0006271)3.41758091
44regulation of centriole replication (GO:0046599)3.39994669
45transcription initiation from RNA polymerase I promoter (GO:0006361)3.39169489
46DNA strand elongation (GO:0022616)3.37862178
47DNA damage response, detection of DNA damage (GO:0042769)3.36391302
48L-methionine biosynthetic process (GO:0071265)3.36114184
49amino acid salvage (GO:0043102)3.36114184
50L-methionine salvage (GO:0071267)3.36114184
51CENP-A containing nucleosome assembly (GO:0034080)3.35908916
52L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.35510629
53DNA replication initiation (GO:0006270)3.34517208
54somatic diversification of immune receptors via somatic mutation (GO:0002566)3.34205977
55somatic hypermutation of immunoglobulin genes (GO:0016446)3.34205977
56maturation of 5.8S rRNA (GO:0000460)3.32924626
57cellular component biogenesis (GO:0044085)3.32459557
58rRNA processing (GO:0006364)3.31181472
59replication fork processing (GO:0031297)3.30585780
60viral mRNA export from host cell nucleus (GO:0046784)3.29729196
61protein localization to kinetochore (GO:0034501)3.29712998
62folic acid-containing compound biosynthetic process (GO:0009396)3.29366425
63mitotic sister chromatid segregation (GO:0000070)3.29022076
64ribosome assembly (GO:0042255)3.28378430
65regulation of cellular amino acid metabolic process (GO:0006521)3.26406439
66positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.26064259
67chromatin remodeling at centromere (GO:0031055)3.25866296
68signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.25843862
69signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.25843862
70signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.25843862
71tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.25050629
72RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.25050629
73kinetochore organization (GO:0051383)3.23526467
74regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.22797708
75DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.22306327
76mitochondrial respiratory chain complex I biogenesis (GO:0097031)3.22090000
77mitochondrial respiratory chain complex I assembly (GO:0032981)3.22090000
78NADH dehydrogenase complex assembly (GO:0010257)3.22090000
79telomere maintenance via recombination (GO:0000722)3.20390531
80signal transduction involved in DNA damage checkpoint (GO:0072422)3.19126925
81signal transduction involved in DNA integrity checkpoint (GO:0072401)3.19126925
82rRNA metabolic process (GO:0016072)3.19095667
83ATP synthesis coupled proton transport (GO:0015986)3.19038307
84energy coupled proton transport, down electrochemical gradient (GO:0015985)3.19038307
85signal transduction involved in cell cycle checkpoint (GO:0072395)3.18830649
86signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.18730369
87intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.18730369
88regulation of translational fidelity (GO:0006450)3.18537816
89tRNA methylation (GO:0030488)3.16864857
90single strand break repair (GO:0000012)3.15121409
91protein complex biogenesis (GO:0070271)3.13705110
92exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.13686665
93establishment of protein localization to mitochondrial membrane (GO:0090151)3.13119312
94sister chromatid segregation (GO:0000819)3.12883485
95DNA replication-dependent nucleosome organization (GO:0034723)3.11647789
96DNA replication-dependent nucleosome assembly (GO:0006335)3.11647789
97deoxyribonucleotide biosynthetic process (GO:0009263)3.11533281
98establishment of integrated proviral latency (GO:0075713)3.09858577
99nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.09710984
100positive regulation of ligase activity (GO:0051351)3.09641274
101telomere maintenance via telomere lengthening (GO:0010833)3.06813544
102peptidyl-histidine modification (GO:0018202)3.06107746
103protein K6-linked ubiquitination (GO:0085020)3.04063073
104mitochondrial DNA replication (GO:0006264)3.03668114
105DNA-templated transcription, elongation (GO:0006354)3.03491116
106DNA-templated transcription, termination (GO:0006353)3.03432842
107transcription elongation from RNA polymerase II promoter (GO:0006368)3.02949486
108guanosine-containing compound biosynthetic process (GO:1901070)3.02405538
109respiratory chain complex IV assembly (GO:0008535)3.02372022
110DNA-dependent DNA replication (GO:0006261)3.01348196
111protein localization to chromosome, centromeric region (GO:0071459)3.00826180
112L-serine metabolic process (GO:0006563)3.00725271
113mitochondrial respiratory chain complex assembly (GO:0033108)3.00450522
114IMP biosynthetic process (GO:0006188)2.99844591
115regulation of centrosome cycle (GO:0046605)2.98855931
116meiotic chromosome segregation (GO:0045132)2.97042489
117metaphase plate congression (GO:0051310)2.96442932
118tRNA modification (GO:0006400)2.96387679
119transcription from mitochondrial promoter (GO:0006390)2.96033871
120amino acid activation (GO:0043038)2.95077120
121tRNA aminoacylation (GO:0043039)2.95077120
122regulation of posttranscriptional gene silencing (GO:0060147)2.95048405
123regulation of gene silencing by miRNA (GO:0060964)2.95048405
124regulation of gene silencing by RNA (GO:0060966)2.95048405
125GTP biosynthetic process (GO:0006183)2.94399684
126formation of translation preinitiation complex (GO:0001731)2.93869582
127mitotic sister chromatid cohesion (GO:0007064)2.93217236
128ubiquinone biosynthetic process (GO:0006744)2.92817510
129quinone biosynthetic process (GO:1901663)2.92817510
130mitotic recombination (GO:0006312)2.91517616
131maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)2.88989725
132tRNA aminoacylation for protein translation (GO:0006418)2.88759897
133pore complex assembly (GO:0046931)2.86534037
134mitotic nuclear envelope disassembly (GO:0007077)2.83854535
135negative regulation of DNA-dependent DNA replication (GO:2000104)2.82542056
136tRNA metabolic process (GO:0006399)2.80180343
137regulation of DNA endoreduplication (GO:0032875)2.77141822
138double-strand break repair via nonhomologous end joining (GO:0006303)2.75792415
139non-recombinational repair (GO:0000726)2.75792415
140histone exchange (GO:0043486)2.75685802
141tetrahydrofolate metabolic process (GO:0046653)2.74419980
142behavioral response to nicotine (GO:0035095)2.73883037
143regulation of mitotic spindle checkpoint (GO:1903504)2.72715975
144regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.72715975
145tRNA processing (GO:0008033)2.72076489
146ncRNA metabolic process (GO:0034660)2.69970839
147ncRNA processing (GO:0034470)2.69620382
148nucleotide-excision repair, DNA gap filling (GO:0006297)2.69575890
149pteridine-containing compound biosynthetic process (GO:0042559)2.67019561
150recombinational repair (GO:0000725)2.65845997
151double-strand break repair via homologous recombination (GO:0000724)2.65567112
152regulation of centrosome duplication (GO:0010824)2.64664093
153methionine biosynthetic process (GO:0009086)2.63806158
154DNA replication-independent nucleosome organization (GO:0034724)2.63430566
155DNA replication-independent nucleosome assembly (GO:0006336)2.63430566
156aspartate family amino acid biosynthetic process (GO:0009067)2.63355749
157IMP metabolic process (GO:0046040)2.63178161
158translesion synthesis (GO:0019985)2.60593211
159positive regulation of chromosome segregation (GO:0051984)2.58600792
160water-soluble vitamin biosynthetic process (GO:0042364)2.57386349
161nuclear envelope disassembly (GO:0051081)2.57118511
162membrane disassembly (GO:0030397)2.57118511

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.24567043
2KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human4.84104561
3MYC_18555785_ChIP-Seq_MESCs_Mouse4.25377150
4JARID1A_20064375_ChIP-Seq_MESCs_Mouse4.12524640
5GABP_17652178_ChIP-ChIP_JURKAT_Human3.86979367
6EST1_17652178_ChIP-ChIP_JURKAT_Human3.80329341
7E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse3.75303050
8ETS1_20019798_ChIP-Seq_JURKAT_Human3.57167526
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.38508570
10CREB1_15753290_ChIP-ChIP_HEK293T_Human3.21479573
11MYC_18358816_ChIP-ChIP_MESCs_Mouse3.10681539
12HCFC1_20581084_ChIP-Seq_MESCs_Mouse3.10452603
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.90230799
14MYC_19030024_ChIP-ChIP_MESCs_Mouse2.89161366
15HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.88406612
16MYC_19079543_ChIP-ChIP_MESCs_Mouse2.80397001
17CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.71355347
18ELF1_17652178_ChIP-ChIP_JURKAT_Human2.68702082
19EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.66701061
20CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human2.60477109
21FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.58927732
22THAP11_20581084_ChIP-Seq_MESCs_Mouse2.42102992
23VDR_23849224_ChIP-Seq_CD4+_Human2.41161651
24YY1_21170310_ChIP-Seq_MESCs_Mouse2.39541661
25DCP1A_22483619_ChIP-Seq_HELA_Human2.36469300
26SALL1_21062744_ChIP-ChIP_HESCs_Human2.32537510
27E2F1_18555785_ChIP-Seq_MESCs_Mouse2.30592510
28SRF_21415370_ChIP-Seq_HL-1_Mouse2.24775136
29NELFA_20434984_ChIP-Seq_ESCs_Mouse2.23211425
30ZNF274_21170338_ChIP-Seq_K562_Hela2.22049599
31MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.21952266
32XRN2_22483619_ChIP-Seq_HELA_Human2.17903858
33FOXP3_21729870_ChIP-Seq_TREG_Human2.16160337
34FOXM1_23109430_ChIP-Seq_U2OS_Human2.12226237
35YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.10908272
36MYCN_21190229_ChIP-Seq_SHEP-21N_Human2.07102922
37GABP_19822575_ChIP-Seq_HepG2_Human1.99794356
38ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.99365712
39TTF2_22483619_ChIP-Seq_HELA_Human1.97013903
40MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.96774273
41PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.92301721
42FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.83678333
43POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.82162856
44NANOG_18555785_ChIP-Seq_MESCs_Mouse1.80980914
45ELK1_19687146_ChIP-ChIP_HELA_Human1.76748330
46MYCN_18555785_ChIP-Seq_MESCs_Mouse1.73333873
47PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.72262195
48POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.68055533
49SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.64601362
50EWS_26573619_Chip-Seq_HEK293_Human1.64265523
51HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.55673310
52FUS_26573619_Chip-Seq_HEK293_Human1.54398176
53NOTCH1_21737748_ChIP-Seq_TLL_Human1.52334680
54IRF1_19129219_ChIP-ChIP_H3396_Human1.50296829
55RBPJ_22232070_ChIP-Seq_NCS_Mouse1.46559131
56TP63_19390658_ChIP-ChIP_HaCaT_Human1.44892163
57NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.44149346
58SOX2_18555785_ChIP-Seq_MESCs_Mouse1.39977707
59PADI4_21655091_ChIP-ChIP_MCF-7_Human1.37909072
60MYC_18940864_ChIP-ChIP_HL60_Human1.36433995
61CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.35361143
62KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.35247828
63ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.34526129
64VDR_22108803_ChIP-Seq_LS180_Human1.33444241
65CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.32846353
66HOXB4_20404135_ChIP-ChIP_EML_Mouse1.32214079
67CIITA_25753668_ChIP-Seq_RAJI_Human1.27607380
68BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.22677832
69KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.22582991
70NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.22304113
71E2F1_21310950_ChIP-Seq_MCF-7_Human1.17962617
72AR_21909140_ChIP-Seq_LNCAP_Human1.14575046
73IGF1R_20145208_ChIP-Seq_DFB_Human1.13133734
74SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.12813866
75FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.10680017
76KDM5A_27292631_Chip-Seq_BREAST_Human1.09507591
77SIN3A_21632747_ChIP-Seq_MESCs_Mouse1.09088328
78GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.09009276
79ZFX_18555785_ChIP-Seq_MESCs_Mouse1.08930281
80CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.08356466
81ESR1_15608294_ChIP-ChIP_MCF-7_Human1.07121833
82CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.06981671
83NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.04639516
84ELK1_22589737_ChIP-Seq_MCF10A_Human1.03163691
85CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.99959401
86ERG_20887958_ChIP-Seq_HPC-7_Mouse0.96946876
87SOX17_20123909_ChIP-Seq_XEN_Mouse0.96460212
88POU5F1_16153702_ChIP-ChIP_HESCs_Human0.94731942
89POU5F1_18700969_ChIP-ChIP_MESCs_Mouse0.93610511
90KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.92975029
91KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.92975029
92KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.92975029
93SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.90857009
94POU3F2_20337985_ChIP-ChIP_501MEL_Human0.88534963
95KAP1_22055183_ChIP-Seq_ESCs_Mouse0.88183470
96SFPI1_20887958_ChIP-Seq_HPC-7_Mouse0.85458455
97TAL1_20887958_ChIP-Seq_HPC-7_Mouse0.85307004
98EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.84798687
99SOX2_18692474_ChIP-Seq_MEFs_Mouse0.84200494
100CTBP2_25329375_ChIP-Seq_LNCAP_Human0.84143016
101E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.82518497
102ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.81586623
103CNOT3_19339689_ChIP-ChIP_MESCs_Mouse0.80244437
104NANOG_16153702_ChIP-ChIP_HESCs_Human0.80220107
105FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.79858790
106TP53_22573176_ChIP-Seq_HFKS_Human0.78922798
107ZFP57_27257070_Chip-Seq_ESCs_Mouse0.78754660
108FLI1_27457419_Chip-Seq_LIVER_Mouse0.78722139
109SOX2_16153702_ChIP-ChIP_HESCs_Human0.78580872
110TAF15_26573619_Chip-Seq_HEK293_Human0.77498173
111GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.75413864
112CTBP1_25329375_ChIP-Seq_LNCAP_Human0.74905896
113SIN3B_21632747_ChIP-Seq_MESCs_Mouse0.74658559
114STAT3_1855785_ChIP-Seq_MESCs_Mouse0.74649364
115MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human0.74414891
116TCF3_18692474_ChIP-Seq_MEFs_Mouse0.73906719
117DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.73584558
118OCT4_18692474_ChIP-Seq_MEFs_Mouse0.73527269
119POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.72647959
120PCGF2_27294783_Chip-Seq_ESCs_Mouse0.71353717
121EGR1_23403033_ChIP-Seq_LIVER_Mouse0.69346109
122ER_23166858_ChIP-Seq_MCF-7_Human0.68536715
123CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.67938034
124CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse0.67861923
125TFEB_21752829_ChIP-Seq_HELA_Human0.67817051
126SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.66403676
127PRDM5_23873026_ChIP-Seq_MEFs_Mouse0.66197666

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.59878516
2MP0008058_abnormal_DNA_repair3.79183540
3MP0003111_abnormal_nucleus_morphology3.62457923
4MP0008057_abnormal_DNA_replication3.44377033
5MP0010094_abnormal_chromosome_stability3.33761060
6MP0004957_abnormal_blastocyst_morpholog3.22198883
7MP0006292_abnormal_olfactory_placode3.21098375
8MP0003718_maternal_effect2.91644194
9MP0003077_abnormal_cell_cycle2.79835928
10MP0008932_abnormal_embryonic_tissue2.52890043
11MP0003136_yellow_coat_color2.45210891
12MP0004133_heterotaxia2.28470735
13MP0009697_abnormal_copulation2.27897716
14MP0001188_hyperpigmentation2.23299516
15MP0003786_premature_aging2.17849663
16MP0003806_abnormal_nucleotide_metabolis2.17451641
17MP0009379_abnormal_foot_pigmentation2.07987962
18MP0002638_abnormal_pupillary_reflex2.04375989
19MP0002132_abnormal_respiratory_system2.02085456
20MP0002102_abnormal_ear_morphology2.00349256
21MP0003315_abnormal_perineum_morphology1.97380806
22MP0008007_abnormal_cellular_replicative1.96061785
23MP0008877_abnormal_DNA_methylation1.85610282
24MP0003941_abnormal_skin_development1.75665140
25MP0008260_abnormal_autophagy1.71967820
26MP0006035_abnormal_mitochondrial_morpho1.64064812
27MP0000566_synostosis1.63431471
28MP0001529_abnormal_vocalization1.61906767
29MP0003890_abnormal_embryonic-extraembry1.55270297
30MP0004147_increased_porphyrin_level1.50829280
31MP0001764_abnormal_homeostasis1.48251540
32MP0002234_abnormal_pharynx_morphology1.47211139
33MP0003123_paternal_imprinting1.45414995
34MP0003186_abnormal_redox_activity1.43221965
35MP0004233_abnormal_muscle_weight1.42757606
36MP0006036_abnormal_mitochondrial_physio1.39966266
37MP0003011_delayed_dark_adaptation1.32599514
38MP0002938_white_spotting1.32277199
39MP0010030_abnormal_orbit_morphology1.30963726
40MP0003119_abnormal_digestive_system1.25588461
41MP0002163_abnormal_gland_morphology1.24657023
42MP0002084_abnormal_developmental_patter1.21250904
43MP0001730_embryonic_growth_arrest1.18129059
44MP0002277_abnormal_respiratory_mucosa1.17946025
45MP0009046_muscle_twitch1.17836362
46MP0004381_abnormal_hair_follicle1.17617011
47MP0002653_abnormal_ependyma_morphology1.16910581
48MP0009672_abnormal_birth_weight1.16060364
49MP0002210_abnormal_sex_determination1.16021411
50MP0002160_abnormal_reproductive_system1.15933212
51MP0010307_abnormal_tumor_latency1.10880826
52MP0005451_abnormal_body_composition1.10858264
53MP0000015_abnormal_ear_pigmentation1.10130094
54MP0005389_reproductive_system_phenotype1.08653092
55MP0004197_abnormal_fetal_growth/weight/1.07617233
56MP0008789_abnormal_olfactory_epithelium1.06262332
57MP0001661_extended_life_span1.05341163
58MP0000427_abnormal_hair_cycle1.05034013
59MP0001286_abnormal_eye_development1.03885371
60MP0000647_abnormal_sebaceous_gland1.03603326
61MP0002736_abnormal_nociception_after1.02988292
62MP0000049_abnormal_middle_ear1.02826637
63MP0005187_abnormal_penis_morphology1.01847041
64MP0002697_abnormal_eye_size1.01358363
65MP0000358_abnormal_cell_content/1.00357369
66MP0005380_embryogenesis_phenotype0.99517451
67MP0001672_abnormal_embryogenesis/_devel0.99517451
68MP0002837_dystrophic_cardiac_calcinosis0.99487813
69MP0005085_abnormal_gallbladder_physiolo0.99279611
70MP0000631_abnormal_neuroendocrine_gland0.99046765
71MP0000569_abnormal_digit_pigmentation0.99023470
72MP0003121_genomic_imprinting0.98728366
73MP0001119_abnormal_female_reproductive0.97362176
74MP0008995_early_reproductive_senescence0.96631599
75MP0006072_abnormal_retinal_apoptosis0.96556406
76MP0001919_abnormal_reproductive_system0.96512516
77MP0004145_abnormal_muscle_electrophysio0.96173887
78MP0000350_abnormal_cell_proliferation0.95519373
79MP0005075_abnormal_melanosome_morpholog0.94772739
80MP0002751_abnormal_autonomic_nervous0.94424209
81MP0001145_abnormal_male_reproductive0.93739829
82MP0002127_abnormal_cardiovascular_syste0.93256755
83MP0003938_abnormal_ear_development0.91880459
84MP0002085_abnormal_embryonic_tissue0.91318122
85MP0003646_muscle_fatigue0.90836376
86MP0001697_abnormal_embryo_size0.90349784
87MP0005551_abnormal_eye_electrophysiolog0.90216960
88MP0006276_abnormal_autonomic_nervous0.88608491
89MP0000026_abnormal_inner_ear0.88570166
90MP0005645_abnormal_hypothalamus_physiol0.87458446
91MP0000313_abnormal_cell_death0.86680299
92MP0001986_abnormal_taste_sensitivity0.85692400
93MP0003861_abnormal_nervous_system0.85532882
94MP0005332_abnormal_amino_acid0.84048297
95MP0003698_abnormal_male_reproductive0.83206478
96MP0004019_abnormal_vitamin_homeostasis0.82774591
97MP0000653_abnormal_sex_gland0.82658464
98MP0001293_anophthalmia0.82030874
99MP0005394_taste/olfaction_phenotype0.81256403
100MP0005499_abnormal_olfactory_system0.81256403
101MP0005266_abnormal_metabolism0.80596410
102MP0000372_irregular_coat_pigmentation0.80251220
103MP0002139_abnormal_hepatobiliary_system0.80145026
104MP0001968_abnormal_touch/_nociception0.79996276
105MP0001727_abnormal_embryo_implantation0.78662649
106MP0005409_darkened_coat_color0.78641655
107MP0002184_abnormal_innervation0.78197909
108MP0002080_prenatal_lethality0.78026194
109MP0000678_abnormal_parathyroid_gland0.77430109
110MP0004142_abnormal_muscle_tone0.77032707
111MP0001929_abnormal_gametogenesis0.76069461
112MP0003755_abnormal_palate_morphology0.75857283
113MP0005395_other_phenotype0.75835505
114MP0003984_embryonic_growth_retardation0.75633759
115MP0005253_abnormal_eye_physiology0.74707608
116MP0005171_absent_coat_pigmentation0.73549254
117MP0002088_abnormal_embryonic_growth/wei0.73032167
118MP0003195_calcinosis0.72966125
119MP0002233_abnormal_nose_morphology0.72863696
120MP0001905_abnormal_dopamine_level0.72163327
121MP0002249_abnormal_larynx_morphology0.71335025
122MP0009703_decreased_birth_body0.69265638
123MP0009745_abnormal_behavioral_response0.69086598
124MP0005379_endocrine/exocrine_gland_phen0.69081535
125MP0003937_abnormal_limbs/digits/tail_de0.68897531
126MP0005670_abnormal_white_adipose0.68478794
127MP0008770_decreased_survivor_rate0.67778732
128MP0003880_abnormal_central_pattern0.66912367
129MP0003950_abnormal_plasma_membrane0.66305663
130MP0004742_abnormal_vestibular_system0.65914671
131MP0005391_vision/eye_phenotype0.65819403
132MP0002111_abnormal_tail_morphology0.65631038
133MP0003567_abnormal_fetal_cardiomyocyte0.65274224
134MP0005365_abnormal_bile_salt0.64320137
135MP0008872_abnormal_physiological_respon0.63520490
136MP0004043_abnormal_pH_regulation0.63264357
137MP0003943_abnormal_hepatobiliary_system0.63090687

Predicted human phenotypes

RankGene SetZ-score
1Acute necrotizing encephalopathy (HP:0006965)3.96083563
2Birth length less than 3rd percentile (HP:0003561)3.64583389
3Abnormal mitochondria in muscle tissue (HP:0008316)3.56189597
4Chromosomal breakage induced by crosslinking agents (HP:0003221)3.54517001
5Mitochondrial inheritance (HP:0001427)3.52669368
6Cerebral hypomyelination (HP:0006808)3.40233405
7Breast hypoplasia (HP:0003187)3.37904403
8Acute encephalopathy (HP:0006846)3.31640097
9Increased CSF lactate (HP:0002490)3.31349119
10Increased serum pyruvate (HP:0003542)3.14542723
11Abnormality of glycolysis (HP:0004366)3.14542723
123-Methylglutaconic aciduria (HP:0003535)3.13839927
13Oral leukoplakia (HP:0002745)3.11501665
14Hepatocellular necrosis (HP:0001404)3.10953960
15Abnormality of the preputium (HP:0100587)3.10297846
16Microvesicular hepatic steatosis (HP:0001414)3.09865065
17Increased serum lactate (HP:0002151)3.08536253
18Meckel diverticulum (HP:0002245)3.05368528
19Progressive macrocephaly (HP:0004481)3.04563354
20Chromsome breakage (HP:0040012)3.04482807
21Reticulocytopenia (HP:0001896)3.00544309
22Hepatic necrosis (HP:0002605)2.96251968
23Abnormality of the ileum (HP:0001549)2.92388990
24Rough bone trabeculation (HP:0100670)2.91727066
25Aplasia/Hypoplasia of the sacrum (HP:0008517)2.78735898
26Aplasia/Hypoplasia of the uvula (HP:0010293)2.77614969
27Increased hepatocellular lipid droplets (HP:0006565)2.77298296
28Muscle abnormality related to mitochondrial dysfunction (HP:0003800)2.75944494
29Abnormality of alanine metabolism (HP:0010916)2.75726924
30Hyperalaninemia (HP:0003348)2.75726924
31Abnormality of pyruvate family amino acid metabolism (HP:0010915)2.75726924
32Hypoplasia of the pons (HP:0012110)2.69639424
33Abnormality of the pons (HP:0007361)2.68962838
34Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)2.66772279
35Absent radius (HP:0003974)2.66376268
36Duplicated collecting system (HP:0000081)2.65243473
37Cerebral edema (HP:0002181)2.64952745
38Lipid accumulation in hepatocytes (HP:0006561)2.63864085
39Patellar aplasia (HP:0006443)2.55190283
40Lactic acidosis (HP:0003128)2.54653560
41Horseshoe kidney (HP:0000085)2.54148140
42Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.50437793
43Decreased activity of mitochondrial respiratory chain (HP:0008972)2.50437793
44Aplasia/Hypoplasia of the patella (HP:0006498)2.49415820
45Aplasia involving forearm bones (HP:0009822)2.48851603
46Absent forearm bone (HP:0003953)2.48851603
47Carpal bone hypoplasia (HP:0001498)2.47863935
48Progressive external ophthalmoplegia (HP:0000590)2.45776626
49Abnormality of pyrimidine metabolism (HP:0004353)2.45080688
50Exercise intolerance (HP:0003546)2.41041410
51Abnormality of the renal collecting system (HP:0004742)2.38219723
52Renal Fanconi syndrome (HP:0001994)2.35508237
53Bone marrow hypocellularity (HP:0005528)2.34748291
54Triphalangeal thumb (HP:0001199)2.33960841
55Aplasia/Hypoplasia involving the musculature (HP:0001460)2.33056410
56Abnormality of chromosome stability (HP:0003220)2.31000709
57Absent thumb (HP:0009777)2.30067524
58Abnormality of the carotid arteries (HP:0005344)2.29599013
59Abnormal trabecular bone morphology (HP:0100671)2.28084135
60Hyperglycinemia (HP:0002154)2.25606570
61Supernumerary spleens (HP:0009799)2.22669644
62Degeneration of anterior horn cells (HP:0002398)2.18383990
63Abnormality of the anterior horn cell (HP:0006802)2.18383990
64Respiratory failure (HP:0002878)2.17437629
65Premature graying of hair (HP:0002216)2.16948318
66Type II lissencephaly (HP:0007260)2.16649109
67Renal cortical cysts (HP:0000803)2.13858310
68Lethargy (HP:0001254)2.13742581
69Sloping forehead (HP:0000340)2.13085297
70Secondary amenorrhea (HP:0000869)2.12525133
71Aplasia/hypoplasia of the uterus (HP:0008684)2.12008955
72Abnormality of serum amino acid levels (HP:0003112)2.11367735
73Abnormal number of erythroid precursors (HP:0012131)2.10826523
74Impulsivity (HP:0100710)2.09834112
75Pancreatic cysts (HP:0001737)2.09135312
76Abnormality of midbrain morphology (HP:0002418)2.09008640
77Molar tooth sign on MRI (HP:0002419)2.09008640
78Partial agenesis of the corpus callosum (HP:0001338)2.08095646
79Optic disc pallor (HP:0000543)2.07552427
80Cellular immunodeficiency (HP:0005374)2.06456264
81Macrocytic anemia (HP:0001972)2.05948425
82Pendular nystagmus (HP:0012043)2.05804454
83Progressive muscle weakness (HP:0003323)2.05532309
84Pancytopenia (HP:0001876)2.04209691
85Colon cancer (HP:0003003)2.03846186
86Hyperglycinuria (HP:0003108)2.03357619
87Reduced antithrombin III activity (HP:0001976)1.99387215
88Volvulus (HP:0002580)1.99198406
89Premature ovarian failure (HP:0008209)1.98701638
90Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.98466936
91Abnormality of cells of the erythroid lineage (HP:0012130)1.98258874
92Unsteady gait (HP:0002317)1.97894275
93CNS demyelination (HP:0007305)1.97079972
94Duodenal stenosis (HP:0100867)1.96345771
95Small intestinal stenosis (HP:0012848)1.96345771
96Abnormality of the labia minora (HP:0012880)1.96325226
97Abnormal protein glycosylation (HP:0012346)1.92118746
98Abnormal glycosylation (HP:0012345)1.92118746
99Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.92118746
100Abnormal protein N-linked glycosylation (HP:0012347)1.92118746
101Progressive inability to walk (HP:0002505)1.91936114
102Ectopic kidney (HP:0000086)1.89844077
103Cerebellar dysplasia (HP:0007033)1.89662573
104Pancreatic fibrosis (HP:0100732)1.89469974
105Facial cleft (HP:0002006)1.88566342
106Abnormality of the duodenum (HP:0002246)1.87126328
107Respiratory difficulties (HP:0002880)1.86507509
108Ureteral duplication (HP:0000073)1.86137430
109Protruding tongue (HP:0010808)1.85915061
110Abnormality of DNA repair (HP:0003254)1.85844621
111Prolonged neonatal jaundice (HP:0006579)1.85665655
112True hermaphroditism (HP:0010459)1.85591590
113Exertional dyspnea (HP:0002875)1.84997007
114Type I transferrin isoform profile (HP:0003642)1.84572916
115Abnormality of homocysteine metabolism (HP:0010919)1.84488034
116Homocystinuria (HP:0002156)1.84488034
117Megaloblastic anemia (HP:0001889)1.83719748
118Abnormality of the renal cortex (HP:0011035)1.81491756
119Abnormal lung lobation (HP:0002101)1.80589829
120Aplastic anemia (HP:0001915)1.80577695
121Increased intramyocellular lipid droplets (HP:0012240)1.80089289
122Sparse eyelashes (HP:0000653)1.79982207
123Increased nuchal translucency (HP:0010880)1.78508048
124Abnormal respiratory motile cilium morphology (HP:0005938)1.77509621
125Abnormal respiratory epithelium morphology (HP:0012253)1.77509621
126Cleft eyelid (HP:0000625)1.77216679
127Lissencephaly (HP:0001339)1.75896274
128Septo-optic dysplasia (HP:0100842)1.75751766
129Glycosuria (HP:0003076)1.75230012
130Small hand (HP:0200055)1.68869259
131Short thumb (HP:0009778)1.67279061
132Methylmalonic acidemia (HP:0002912)1.64912025
133Glioma (HP:0009733)1.63938695
134Aplasia/Hypoplasia of the tibia (HP:0005772)1.63787956
135Retinal dysplasia (HP:0007973)1.63528712
136Sclerocornea (HP:0000647)1.62404561
137Methylmalonic aciduria (HP:0012120)1.62309052
138Multiple enchondromatosis (HP:0005701)1.61362481
139Clubbing of toes (HP:0100760)1.61280503
140Nephronophthisis (HP:0000090)1.58317179
141Inability to walk (HP:0002540)1.57305024
142Bilateral microphthalmos (HP:0007633)1.56528545
143Abnormality of methionine metabolism (HP:0010901)1.55775930
144Ependymoma (HP:0002888)1.54357795
145Dandy-Walker malformation (HP:0001305)1.53685901
146Septate vagina (HP:0001153)1.51836348
147Congenital stationary night blindness (HP:0007642)1.50984382
148Abnormal number of incisors (HP:0011064)1.50962300

Predicted kinase interactions (KEA)

RankGene SetZ-score
1STK164.87058357
2BUB14.83313337
3SRPK13.42644358
4EIF2AK13.42211662
5WEE13.03116745
6MKNK22.51975594
7TLK12.46067360
8FRK2.45916516
9PLK42.35294395
10ZAK2.32007762
11MKNK12.09591522
12VRK12.02673620
13EIF2AK31.95876818
14TSSK61.95195644
15AKT31.93168700
16PBK1.85126097
17NME21.80722066
18PNCK1.66948171
19IRAK31.66842842
20BCKDK1.66357763
21NME11.64753081
22TTK1.62857877
23PLK11.60165962
24EIF2AK21.55211977
25CASK1.52911387
26DYRK31.52798817
27PLK31.47517769
28WNK41.43785106
29WNK31.43717872
30CDC71.43310493
31TESK21.35412844
32AURKA1.33149185
33PASK1.30139490
34BRSK21.29654736
35TAF11.24933014
36MAP4K21.24537094
37STK38L1.22935657
38VRK21.22779871
39CDK71.19597245
40EPHA21.19273548
41MAP3K41.15055853
42CSNK1G11.13543739
43BRAF1.11741770
44DYRK21.11012063
45AURKB1.07587715
46CCNB11.03459902
47CSNK1G31.02605473
48YES11.02235093
49PINK11.00958186
50ACVR1B0.99626002
51INSRR0.98769463
52SIK30.96721185
53CDK80.95187265
54CSNK1G20.94047565
55CHEK20.93469099
56ATR0.91888758
57BRSK10.90631951
58LATS10.90601880
59CSNK1A1L0.89429219
60STK390.87254913
61PHKG10.86010975
62PHKG20.86010975
63MAP2K70.84331496
64BCR0.82775946
65TAOK20.82636380
66BMPR20.81845889
67BRD40.81351845
68MST40.80965482
69IRAK40.80888113
70TNIK0.80444210
71TGFBR10.80105211
72PRKCI0.77368282
73EEF2K0.75641587
74NEK20.75514714
75ALK0.75310043
76CAMK1D0.75192921
77NEK10.73232376
78GRK10.72582465
79CSNK2A10.72175924
80IRAK20.71433137
81RPS6KB20.71056363
82TRIM280.70531881
83OBSCN0.69236993
84NUAK10.67063872
85CAMK1G0.66224357
86STK30.64898840
87BMPR1B0.63847496
88CHEK10.63405907
89OXSR10.62848866
90NEK60.60868602
91ADRBK20.60778765
92CSNK2A20.59327234
93PRPF4B0.58611473
94LATS20.57927827
95CDK30.56698182
96MARK10.55774324
97BLK0.54645617
98ERBB40.54578581
99DYRK1A0.52914997
100CDK120.52333144
101STK40.51350796
102PRKDC0.50260489
103MAPKAPK50.49896414
104PIM20.49638623
105KDR0.49562831
106ERBB30.48155866
107GRK70.46363911
108RPS6KA50.45951361
109ABL20.45564135
110ATM0.45215910
111MAP3K120.44991520
112CAMK2B0.42452451
113LIMK10.42114594
114CDK20.41967448
115CDK10.41716021
116NEK90.40574753
117AKT20.39475206
118PRKCG0.37628873
119MAP3K110.37588690
120MAP3K90.36717460
121CSNK1A10.35435964
122MAPK140.34915268
123CSNK1E0.34837524
124MAPK130.34696230
125UHMK10.34474375
126MYLK0.34376346
127PAK10.32432188
128PLK20.31352415
129RPS6KA40.27107396
130MELK0.26961649
131CAMK2G0.26856966
132TXK0.24735965
133PDK20.24438481
134CDK40.24166278
135IRAK10.23876711
136CAMK2D0.22209049

Predicted pathways (KEGG)

RankGene SetZ-score
1RNA polymerase_Homo sapiens_hsa030204.26613757
2Proteasome_Homo sapiens_hsa030504.01764452
3DNA replication_Homo sapiens_hsa030303.28172504
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.27959847
5Mismatch repair_Homo sapiens_hsa034303.26480765
6Ribosome_Homo sapiens_hsa030103.18091217
7Homologous recombination_Homo sapiens_hsa034402.81679581
8Pyrimidine metabolism_Homo sapiens_hsa002402.75611782
9Spliceosome_Homo sapiens_hsa030402.63715266
10Nucleotide excision repair_Homo sapiens_hsa034202.51492578
11Oxidative phosphorylation_Homo sapiens_hsa001902.48507112
12Fanconi anemia pathway_Homo sapiens_hsa034602.46078372
13One carbon pool by folate_Homo sapiens_hsa006702.26572274
14RNA transport_Homo sapiens_hsa030132.26505074
15Base excision repair_Homo sapiens_hsa034102.26297009
16Parkinsons disease_Homo sapiens_hsa050122.11387366
17Basal transcription factors_Homo sapiens_hsa030222.08965613
18Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009702.08358490
19Huntingtons disease_Homo sapiens_hsa050161.86170507
20Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.82526652
21Vitamin B6 metabolism_Homo sapiens_hsa007501.81251988
22Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.76727248
23Non-homologous end-joining_Homo sapiens_hsa034501.65869070
24Purine metabolism_Homo sapiens_hsa002301.64116418
25Cell cycle_Homo sapiens_hsa041101.61845883
26RNA degradation_Homo sapiens_hsa030181.59261837
27Protein export_Homo sapiens_hsa030601.46471957
28Folate biosynthesis_Homo sapiens_hsa007901.38510343
29Drug metabolism - other enzymes_Homo sapiens_hsa009831.31100751
30Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004001.29759967
31Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.28586374
32Alzheimers disease_Homo sapiens_hsa050101.28051515
33Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.27497253
34Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.16722077
35Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.11008546
36Regulation of autophagy_Homo sapiens_hsa041401.10929347
37mRNA surveillance pathway_Homo sapiens_hsa030151.10507129
38Cysteine and methionine metabolism_Homo sapiens_hsa002701.06121169
39Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.03345879
40Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.02517246
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.00619096
42Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007601.00200600
43Nicotine addiction_Homo sapiens_hsa050330.89779787
44Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.89677415
45Nitrogen metabolism_Homo sapiens_hsa009100.84412187
46Sulfur relay system_Homo sapiens_hsa041220.84334985
47Lysine degradation_Homo sapiens_hsa003100.82908487
48Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.80960818
49Arginine and proline metabolism_Homo sapiens_hsa003300.80044108
50Epstein-Barr virus infection_Homo sapiens_hsa051690.79878209
51Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.79277207
52Metabolic pathways_Homo sapiens_hsa011000.79038193
53Glutathione metabolism_Homo sapiens_hsa004800.76558324
54Biosynthesis of amino acids_Homo sapiens_hsa012300.75678760
55p53 signaling pathway_Homo sapiens_hsa041150.75168262
56Arginine biosynthesis_Homo sapiens_hsa002200.75140122
57Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.74507512
58Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.73277999
59Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.73241433
60Selenocompound metabolism_Homo sapiens_hsa004500.68230502
61Steroid biosynthesis_Homo sapiens_hsa001000.67989349
62Fatty acid elongation_Homo sapiens_hsa000620.65561653
63Synthesis and degradation of ketone bodies_Homo sapiens_hsa000720.64953100
64Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.63395660
65Cardiac muscle contraction_Homo sapiens_hsa042600.63069762
66N-Glycan biosynthesis_Homo sapiens_hsa005100.61972093
67Maturity onset diabetes of the young_Homo sapiens_hsa049500.61169750
68Retinol metabolism_Homo sapiens_hsa008300.61090397
69Carbon metabolism_Homo sapiens_hsa012000.60907043
70Arachidonic acid metabolism_Homo sapiens_hsa005900.60259080
71Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.59580339
72Sulfur metabolism_Homo sapiens_hsa009200.57744203
73Phenylalanine metabolism_Homo sapiens_hsa003600.55346666
74Cyanoamino acid metabolism_Homo sapiens_hsa004600.54873344
75Peroxisome_Homo sapiens_hsa041460.54022445
76Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.53665377
77Steroid hormone biosynthesis_Homo sapiens_hsa001400.52941098
78Phototransduction_Homo sapiens_hsa047440.52558580
79beta-Alanine metabolism_Homo sapiens_hsa004100.52414453
80Fatty acid metabolism_Homo sapiens_hsa012120.52069294
81Fructose and mannose metabolism_Homo sapiens_hsa000510.51683721
82Taste transduction_Homo sapiens_hsa047420.49105050
83Vitamin digestion and absorption_Homo sapiens_hsa049770.47435096
84Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.46443357
85Fatty acid biosynthesis_Homo sapiens_hsa000610.45473434
86Propanoate metabolism_Homo sapiens_hsa006400.45287222
87Tyrosine metabolism_Homo sapiens_hsa003500.44581419
88Tryptophan metabolism_Homo sapiens_hsa003800.44004285
89Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.40864602
90Systemic lupus erythematosus_Homo sapiens_hsa053220.38420480
91Pentose phosphate pathway_Homo sapiens_hsa000300.38032714
92Butanoate metabolism_Homo sapiens_hsa006500.37278286
93Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.36720953
94Hippo signaling pathway_Homo sapiens_hsa043900.36319849
95Ether lipid metabolism_Homo sapiens_hsa005650.35742686
96Oocyte meiosis_Homo sapiens_hsa041140.35729904
97Chemical carcinogenesis_Homo sapiens_hsa052040.35278486
98Linoleic acid metabolism_Homo sapiens_hsa005910.34603758
99Caffeine metabolism_Homo sapiens_hsa002320.34509662
100Primary bile acid biosynthesis_Homo sapiens_hsa001200.31165862
101Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29976221
102Pyruvate metabolism_Homo sapiens_hsa006200.29522615
103TGF-beta signaling pathway_Homo sapiens_hsa043500.27762604
104Galactose metabolism_Homo sapiens_hsa000520.27044850
105Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.22437264
106Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.21435614
107Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.20299489
108Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.18899242
109Olfactory transduction_Homo sapiens_hsa047400.16608806
110Collecting duct acid secretion_Homo sapiens_hsa049660.16568172
111Herpes simplex infection_Homo sapiens_hsa051680.15916473
112Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.14747740
113Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.13460890
114Fatty acid degradation_Homo sapiens_hsa000710.13005831
115Histidine metabolism_Homo sapiens_hsa003400.12025932
116Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.11900481
117Glycerophospholipid metabolism_Homo sapiens_hsa005640.11356387
118alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.10408433
119Basal cell carcinoma_Homo sapiens_hsa052170.09524475
120Autoimmune thyroid disease_Homo sapiens_hsa053200.09157086
121Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.08059031
122Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.07269515

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