Rank | Gene Set | Z-score |
---|---|---|
1 | * cartilage condensation (GO:0001502) | 9.70019357 |
2 | * cell aggregation (GO:0098743) | 9.70019357 |
3 | notochord development (GO:0030903) | 8.87571095 |
4 | limb bud formation (GO:0060174) | 8.84980124 |
5 | * chondrocyte development (GO:0002063) | 8.60298390 |
6 | positive regulation of extracellular matrix organization (GO:1903055) | 8.06166731 |
7 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 8.02272935 |
8 | * collagen fibril organization (GO:0030199) | 7.21354461 |
9 | cartilage development (GO:0051216) | 6.49492559 |
10 | embryonic skeletal joint morphogenesis (GO:0060272) | 6.45028935 |
11 | chondroitin sulfate biosynthetic process (GO:0030206) | 6.06285009 |
12 | sphingomyelin metabolic process (GO:0006684) | 5.98458639 |
13 | replacement ossification (GO:0036075) | 5.98075134 |
14 | endochondral ossification (GO:0001958) | 5.98075134 |
15 | chondrocyte differentiation (GO:0002062) | 5.49803362 |
16 | protein retention in ER lumen (GO:0006621) | 5.40286186 |
17 | endothelial cell morphogenesis (GO:0001886) | 5.37405927 |
18 | nucleotide-sugar biosynthetic process (GO:0009226) | 5.36871287 |
19 | regulation of extracellular matrix disassembly (GO:0010715) | 5.19788141 |
20 | * collagen catabolic process (GO:0030574) | 5.16062078 |
21 | positive regulation of chondrocyte differentiation (GO:0032332) | 5.13921140 |
22 | * proteoglycan metabolic process (GO:0006029) | 5.13884792 |
23 | keratan sulfate biosynthetic process (GO:0018146) | 5.13198749 |
24 | protein heterotrimerization (GO:0070208) | 5.12426339 |
25 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 5.04717241 |
26 | skeletal system development (GO:0001501) | 5.01201478 |
27 | * collagen metabolic process (GO:0032963) | 4.95802976 |
28 | peptidyl-proline hydroxylation (GO:0019511) | 4.89165651 |
29 | regulation of extracellular matrix organization (GO:1903053) | 4.71384244 |
30 | * multicellular organismal catabolic process (GO:0044243) | 4.70780453 |
31 | cellular glucuronidation (GO:0052695) | 4.70232834 |
32 | * multicellular organismal macromolecule metabolic process (GO:0044259) | 4.62527356 |
33 | positive regulation of cartilage development (GO:0061036) | 4.58659201 |
34 | iron ion import (GO:0097286) | 4.56011973 |
35 | negative regulation of gluconeogenesis (GO:0045721) | 4.50669747 |
36 | * multicellular organismal metabolic process (GO:0044236) | 4.39999088 |
37 | hypotonic response (GO:0006971) | 4.33961091 |
38 | lipopolysaccharide biosynthetic process (GO:0009103) | 4.29023895 |
39 | cellular response to BMP stimulus (GO:0071773) | 4.26809702 |
40 | response to BMP (GO:0071772) | 4.26809702 |
41 | short-term memory (GO:0007614) | 4.24426615 |
42 | endocardial cushion morphogenesis (GO:0003203) | 4.23031682 |
43 | regulation of plasminogen activation (GO:0010755) | 4.20878588 |
44 | glucuronate metabolic process (GO:0019585) | 4.19503284 |
45 | uronic acid metabolic process (GO:0006063) | 4.19503284 |
46 | keratan sulfate metabolic process (GO:0042339) | 4.16105512 |
47 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 4.09347122 |
48 | chondrocyte proliferation (GO:0035988) | 4.08224085 |
49 | * extracellular matrix disassembly (GO:0022617) | 4.08100046 |
50 | metanephric mesenchyme development (GO:0072075) | 4.06116843 |
51 | glycosaminoglycan biosynthetic process (GO:0006024) | 4.04883430 |
52 | negative regulation of smooth muscle cell differentiation (GO:0051151) | 4.03091272 |
53 | cell migration involved in heart development (GO:0060973) | 4.00527678 |
54 | regulation of chondrocyte differentiation (GO:0032330) | 3.99574402 |
55 | aminoglycan biosynthetic process (GO:0006023) | 3.99419877 |
56 | basement membrane organization (GO:0071711) | 3.96320649 |
57 | extracellular fibril organization (GO:0043206) | 3.92961105 |
58 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 3.89284854 |
59 | protein hydroxylation (GO:0018126) | 3.86910922 |
60 | kidney mesenchyme development (GO:0072074) | 3.86499305 |
61 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.86120034 |
62 | * endodermal cell differentiation (GO:0035987) | 3.86003570 |
63 | response to gravity (GO:0009629) | 3.84535552 |
64 | chondroitin sulfate metabolic process (GO:0030204) | 3.79814040 |
65 | regulation of establishment of planar polarity (GO:0090175) | 3.76018899 |
66 | bone trabecula formation (GO:0060346) | 3.75313018 |
67 | regulation of cartilage development (GO:0061035) | 3.73852320 |
68 | UDP-N-acetylglucosamine metabolic process (GO:0006047) | 3.71389112 |
69 | myelin assembly (GO:0032288) | 3.71233284 |
70 | axon extension involved in axon guidance (GO:0048846) | 3.71166690 |
71 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.71166690 |
72 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 3.68134057 |
73 | establishment of tissue polarity (GO:0007164) | 3.68020028 |
74 | establishment of planar polarity (GO:0001736) | 3.68020028 |
75 | positive regulation of hormone biosynthetic process (GO:0046886) | 3.65371695 |
76 | ossification (GO:0001503) | 3.65254207 |
77 | glycosaminoglycan catabolic process (GO:0006027) | 3.64231304 |
78 | paraxial mesoderm development (GO:0048339) | 3.62037749 |
79 | lipopolysaccharide metabolic process (GO:0008653) | 3.57812462 |
80 | COPII vesicle coating (GO:0048208) | 3.56798844 |
81 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.56021672 |
82 | cochlea morphogenesis (GO:0090103) | 3.51945733 |
83 | skin morphogenesis (GO:0043589) | 3.49545385 |
84 | outer ear morphogenesis (GO:0042473) | 3.47567463 |
85 | * extracellular matrix organization (GO:0030198) | 3.46025849 |
86 | * extracellular structure organization (GO:0043062) | 3.45204069 |
87 | mesenchyme morphogenesis (GO:0072132) | 3.43763343 |
88 | aminoglycan catabolic process (GO:0006026) | 3.41427103 |
89 | sulfur compound catabolic process (GO:0044273) | 3.41033134 |
90 | mesenchymal-epithelial cell signaling (GO:0060638) | 3.39248151 |
91 | lateral sprouting from an epithelium (GO:0060601) | 3.38962851 |
92 | camera-type eye morphogenesis (GO:0048593) | 3.38478334 |
93 | * glycoprotein metabolic process (GO:0009100) | 3.33506634 |
94 | negative regulation of cartilage development (GO:0061037) | 3.29841420 |
95 | convergent extension (GO:0060026) | 3.29490029 |
96 | proteoglycan biosynthetic process (GO:0030166) | 3.27613698 |
97 | regulation of bone mineralization (GO:0030500) | 3.27609554 |
98 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.26964421 |
99 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.26706943 |
100 | negative regulation of embryonic development (GO:0045992) | 3.23101294 |
101 | non-canonical Wnt signaling pathway (GO:0035567) | 3.22951402 |
102 | embryonic viscerocranium morphogenesis (GO:0048703) | 3.22515324 |
103 | Golgi transport vesicle coating (GO:0048200) | 3.22377783 |
104 | COPI coating of Golgi vesicle (GO:0048205) | 3.22377783 |
105 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.21658555 |
106 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.13652788 |
107 | wound healing, spreading of epidermal cells (GO:0035313) | 3.13569165 |
108 | negative regulation of mesenchymal cell apoptotic process (GO:2001054) | 3.10695624 |
109 | craniofacial suture morphogenesis (GO:0097094) | 3.10552955 |
110 | regulation of integrin-mediated signaling pathway (GO:2001044) | 3.09148625 |
111 | mucopolysaccharide metabolic process (GO:1903510) | 3.07718609 |
112 | otic vesicle formation (GO:0030916) | 3.07501124 |
113 | regulation of cell maturation (GO:1903429) | 3.07399827 |
114 | fibril organization (GO:0097435) | 3.07322748 |
115 | negative chemotaxis (GO:0050919) | 3.05048171 |
116 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 3.02966089 |
117 | glomerular basement membrane development (GO:0032836) | 3.02078917 |
118 | regulation of axon extension involved in axon guidance (GO:0048841) | 3.01276443 |
119 | regulation of biomineral tissue development (GO:0070167) | 3.00176999 |
120 | nucleotide-sugar metabolic process (GO:0009225) | 2.99669685 |
121 | negative regulation of glycogen biosynthetic process (GO:0045719) | 2.99533810 |
122 | regulation of steroid hormone biosynthetic process (GO:0090030) | 2.95873096 |
123 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.93988549 |
124 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 2.93827133 |
125 | cell adhesion mediated by integrin (GO:0033627) | 2.92259413 |
126 | negative regulation of endothelial cell proliferation (GO:0001937) | 2.91899574 |
127 | bone development (GO:0060348) | 2.91793956 |
128 | regulation of axon guidance (GO:1902667) | 2.91708634 |
129 | regulation of cardioblast differentiation (GO:0051890) | 2.91599866 |
130 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.91330141 |
131 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.91104633 |
132 | regulation of response to osmotic stress (GO:0047484) | 2.90938545 |
133 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.89492807 |
134 | * connective tissue development (GO:0061448) | 2.89210368 |
135 | presynaptic membrane assembly (GO:0097105) | 2.88244191 |
136 | radial glial cell differentiation (GO:0060019) | 2.87625653 |
137 | epithelial to mesenchymal transition (GO:0001837) | 2.86725009 |
138 | positive regulation of stem cell differentiation (GO:2000738) | 2.86679493 |
139 | positive regulation of extrinsic apoptotic signaling pathway in absence of ligand (GO:2001241) | 2.85756769 |
140 | positive regulation of male gonad development (GO:2000020) | 2.83887458 |
141 | pericardium development (GO:0060039) | 2.83182528 |
142 | dermatan sulfate biosynthetic process (GO:0030208) | 2.82654458 |
143 | positive regulation of osteoblast proliferation (GO:0033690) | 2.82282041 |
144 | eye morphogenesis (GO:0048592) | 2.81535647 |
145 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 2.80677361 |
146 | negative regulation of axon guidance (GO:1902668) | 2.80527007 |
147 | negative regulation of glycogen metabolic process (GO:0070874) | 2.79651836 |
148 | positive regulation of smoothened signaling pathway (GO:0045880) | 2.78888243 |
149 | axon extension (GO:0048675) | 2.76441640 |
150 | artery development (GO:0060840) | 2.73873802 |
151 | wound healing, spreading of cells (GO:0044319) | 2.73642476 |
152 | myoblast fusion (GO:0007520) | 2.73005290 |
153 | dermatan sulfate metabolic process (GO:0030205) | 2.71093504 |
154 | tooth mineralization (GO:0034505) | 2.68205933 |
155 | axonal fasciculation (GO:0007413) | 2.67554564 |
156 | substrate-dependent cell migration (GO:0006929) | 2.65539381 |
157 | embryonic cranial skeleton morphogenesis (GO:0048701) | 2.64624184 |
158 | positive regulation of mesenchymal cell proliferation (GO:0002053) | 2.64613113 |
159 | hippo signaling (GO:0035329) | 2.64309955 |
160 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 2.63799786 |
161 | Notch signaling involved in heart development (GO:0061314) | 2.62840511 |
162 | neuron recognition (GO:0008038) | 2.61083446 |
163 | neural crest cell development (GO:0014032) | 2.60485488 |
164 | protein localization to cell surface (GO:0034394) | 2.58813588 |
165 | cellular response to amino acid stimulus (GO:0071230) | 2.58128064 |
166 | cerebral cortex radially oriented cell migration (GO:0021799) | 2.53926295 |
167 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 2.52185588 |
168 | face morphogenesis (GO:0060325) | 2.51436744 |
169 | postsynaptic membrane organization (GO:0001941) | 2.50276793 |
170 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 2.50102583 |
171 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.49667767 |
172 | presynaptic membrane organization (GO:0097090) | 2.49381514 |
173 | regulation of mesenchymal cell proliferation (GO:0010464) | 2.48740018 |
174 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 13.8549886 |
175 | keratan sulfate catabolic process (GO:0042340) | 10.8588396 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 8.49338264 |
2 | AR_21572438_ChIP-Seq_LNCaP_Human | 5.39161862 |
3 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.78549910 |
4 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.84467863 |
5 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 3.46395201 |
6 | GATA1_22025678_ChIP-Seq_K562_Human | 3.34377475 |
7 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.96861043 |
8 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.87706864 |
9 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.62939887 |
10 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 2.60289135 |
11 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.55590672 |
12 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 2.35801967 |
13 | CJUN_26792858_Chip-Seq_BT549_Human | 2.23392893 |
14 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.22157324 |
15 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.19328001 |
16 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.16089949 |
17 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.05872674 |
18 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.00683657 |
19 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.97058653 |
20 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 1.93889374 |
21 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.92023999 |
22 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.88610261 |
23 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.87814253 |
24 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.78551814 |
25 | * ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.76188900 |
26 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.75508609 |
27 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.71238929 |
28 | TP53_16413492_ChIP-PET_HCT116_Human | 1.71024313 |
29 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.69384263 |
30 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.68314388 |
31 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.64418658 |
32 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.64414166 |
33 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.64414166 |
34 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.56516998 |
35 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.56516998 |
36 | RXR_22108803_ChIP-Seq_LS180_Human | 1.56426830 |
37 | * HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.56185601 |
38 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.55655166 |
39 | * ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.55333551 |
40 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.52249982 |
41 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.51189421 |
42 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.51070566 |
43 | * CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.48769953 |
44 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.48644370 |
45 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.45976679 |
46 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.45375540 |
47 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.42930994 |
48 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.42535728 |
49 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.41936765 |
50 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.41190051 |
51 | * KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.39628690 |
52 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.39563494 |
53 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.38102071 |
54 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.37612350 |
55 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.37274776 |
56 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.37092421 |
57 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.35187853 |
58 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.31913381 |
59 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.31665172 |
60 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.30256355 |
61 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.29909586 |
62 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.29885461 |
63 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.28826445 |
64 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.28797824 |
65 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.27754389 |
66 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.25925769 |
67 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.25842064 |
68 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.25189519 |
69 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.24711475 |
70 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.24517201 |
71 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.23779454 |
72 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.22719312 |
73 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.22643173 |
74 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.21893288 |
75 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.20783274 |
76 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.20783274 |
77 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.19895934 |
78 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.19777272 |
79 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.19716384 |
80 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.18779812 |
81 | * RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.18661968 |
82 | FUS_26573619_Chip-Seq_HEK293_Human | 1.18163284 |
83 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.16362928 |
84 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.15459075 |
85 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.13855528 |
86 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.13172585 |
87 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.12881829 |
88 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.12585240 |
89 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.12107147 |
90 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.11847178 |
91 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.10759996 |
92 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 1.10730846 |
93 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.10612053 |
94 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.10428247 |
95 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10366904 |
96 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.09640642 |
97 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.09351537 |
98 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08179853 |
99 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.07802113 |
100 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.07559402 |
101 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.07559402 |
102 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.06425134 |
103 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.06397558 |
104 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.06378803 |
105 | EWS_26573619_Chip-Seq_HEK293_Human | 1.04871487 |
106 | * SOX9_26525672_Chip-Seq_HEART_Mouse | 1.04703528 |
107 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04042402 |
108 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.03610229 |
109 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.03600850 |
110 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.03298496 |
111 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.02835446 |
112 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.02363094 |
113 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.02265500 |
114 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 1.02245209 |
115 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.01380957 |
116 | CEBPB_26923725_Chip-Seq_MESODERM_Mouse | 1.01208847 |
117 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.01202399 |
118 | * SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.01183439 |
119 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 0.99976935 |
120 | * KDM2B_26808549_Chip-Seq_REH_Human | 0.98722297 |
121 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 0.97649541 |
122 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.97514845 |
123 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.97396831 |
124 | AR_25329375_ChIP-Seq_VCAP_Human | 0.95970251 |
125 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.95180670 |
126 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.94979436 |
127 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.94180300 |
128 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.93968686 |
129 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 0.93370852 |
130 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.93315155 |
131 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.92897518 |
132 | * CTBP2_25329375_ChIP-Seq_LNCAP_Human | 0.92144179 |
133 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.91280370 |
134 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.90445254 |
135 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 0.90290423 |
136 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 0.90213209 |
137 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.88169212 |
138 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.85923528 |
139 | * NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.85400420 |
140 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 0.85280770 |
141 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.84837511 |
142 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.84781886 |
143 | TP63_23658742_ChIP-Seq_EP156T_Human | 0.84628011 |
144 | P300_19829295_ChIP-Seq_ESCs_Human | 0.82871834 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0004134_abnormal_chest_morphology | 6.02929562 |
2 | MP0002933_joint_inflammation | 5.77410113 |
3 | MP0005503_abnormal_tendon_morphology | 5.20522241 |
4 | MP0009250_abnormal_appendicular_skeleto | 4.22966170 |
5 | * MP0002282_abnormal_trachea_morphology | 4.12665435 |
6 | * MP0000163_abnormal_cartilage_morphology | 3.93813666 |
7 | MP0003646_muscle_fatigue | 3.56283971 |
8 | MP0005257_abnormal_intraocular_pressure | 3.49798595 |
9 | MP0009780_abnormal_chondrocyte_physiolo | 3.33483899 |
10 | * MP0002115_abnormal_skeleton_extremities | 3.31812851 |
11 | MP0008438_abnormal_cutaneous_collagen | 3.11613497 |
12 | MP0001299_abnormal_eye_distance/ | 2.82200777 |
13 | MP0003123_paternal_imprinting | 2.80682479 |
14 | MP0002089_abnormal_postnatal_growth/wei | 2.77546032 |
15 | * MP0002113_abnormal_skeleton_development | 2.76675667 |
16 | MP0005508_abnormal_skeleton_morphology | 2.63863777 |
17 | MP0005171_absent_coat_pigmentation | 2.58383874 |
18 | MP0005390_skeleton_phenotype | 2.42207727 |
19 | MP0001533_abnormal_skeleton_physiology | 2.33925754 |
20 | MP0009384_cardiac_valve_regurgitation | 2.32397346 |
21 | MP0005275_abnormal_skin_tensile | 2.31180864 |
22 | * MP0002896_abnormal_bone_mineralization | 2.24227666 |
23 | MP0001270_distended_abdomen | 2.21338133 |
24 | MP0001542_abnormal_bone_strength | 2.17438127 |
25 | MP0002909_abnormal_adrenal_gland | 2.15607868 |
26 | * MP0002109_abnormal_limb_morphology | 2.14584451 |
27 | MP0004272_abnormal_basement_membrane | 1.87165024 |
28 | MP0003283_abnormal_digestive_organ | 1.83614586 |
29 | MP0003279_aneurysm | 1.78048744 |
30 | * MP0003795_abnormal_bone_structure | 1.76945037 |
31 | MP0010368_abnormal_lymphatic_system | 1.76238137 |
32 | MP0000537_abnormal_urethra_morphology | 1.74912391 |
33 | * MP0000762_abnormal_tongue_morphology | 1.74106713 |
34 | MP0000049_abnormal_middle_ear | 1.69043200 |
35 | MP0000751_myopathy | 1.66226108 |
36 | * MP0002116_abnormal_craniofacial_bone | 1.62281665 |
37 | MP0002108_abnormal_muscle_morphology | 1.61768447 |
38 | MP0002938_white_spotting | 1.59225025 |
39 | * MP0003755_abnormal_palate_morphology | 1.58222957 |
40 | MP0003787_abnormal_imprinting | 1.55172511 |
41 | MP0002163_abnormal_gland_morphology | 1.54686614 |
42 | MP0003705_abnormal_hypodermis_morpholog | 1.47052465 |
43 | MP0003656_abnormal_erythrocyte_physiolo | 1.46066569 |
44 | MP0003136_yellow_coat_color | 1.43852338 |
45 | MP0000778_abnormal_nervous_system | 1.42821659 |
46 | MP0002233_abnormal_nose_morphology | 1.39613435 |
47 | MP0008004_abnormal_stomach_pH | 1.37253188 |
48 | MP0002249_abnormal_larynx_morphology | 1.35036131 |
49 | MP0003937_abnormal_limbs/digits/tail_de | 1.31387081 |
50 | MP0010030_abnormal_orbit_morphology | 1.29808009 |
51 | MP0002998_abnormal_bone_remodeling | 1.28370190 |
52 | * MP0000432_abnormal_head_morphology | 1.28204604 |
53 | MP0002697_abnormal_eye_size | 1.26401036 |
54 | MP0005023_abnormal_wound_healing | 1.26074777 |
55 | MP0002111_abnormal_tail_morphology | 1.25521685 |
56 | MP0003566_abnormal_cell_adhesion | 1.21122047 |
57 | MP0003385_abnormal_body_wall | 1.19755741 |
58 | MP0000767_abnormal_smooth_muscle | 1.15670811 |
59 | * MP0002114_abnormal_axial_skeleton | 1.11008387 |
60 | MP0005197_abnormal_uvea_morphology | 1.09479348 |
61 | MP0001958_emphysema | 1.07937790 |
62 | MP0000569_abnormal_digit_pigmentation | 1.07778400 |
63 | MP0003122_maternal_imprinting | 1.07662411 |
64 | MP0001879_abnormal_lymphatic_vessel | 1.06525197 |
65 | MP0005187_abnormal_penis_morphology | 1.05733343 |
66 | MP0004197_abnormal_fetal_growth/weight/ | 1.05364253 |
67 | MP0003121_genomic_imprinting | 1.05076475 |
68 | MP0003091_abnormal_cell_migration | 1.04583414 |
69 | MP0000343_altered_response_to | 1.03386984 |
70 | MP0001663_abnormal_digestive_system | 1.03366791 |
71 | MP0004858_abnormal_nervous_system | 1.03364399 |
72 | MP0005381_digestive/alimentary_phenotyp | 1.03047266 |
73 | MP0003942_abnormal_urinary_system | 1.01652786 |
74 | MP0002932_abnormal_joint_morphology | 1.01597053 |
75 | MP0001293_anophthalmia | 1.01502348 |
76 | * MP0003935_abnormal_craniofacial_develop | 1.00305923 |
77 | MP0004885_abnormal_endolymph | 0.97015349 |
78 | MP0004859_abnormal_synaptic_plasticity | 0.97013337 |
79 | MP0003436_decreased_susceptibility_to | 0.96764084 |
80 | MP0002092_abnormal_eye_morphology | 0.96307425 |
81 | MP0002102_abnormal_ear_morphology | 0.93741640 |
82 | MP0005164_abnormal_response_to | 0.91680615 |
83 | MP0004484_altered_response_of | 0.90311799 |
84 | MP0004084_abnormal_cardiac_muscle | 0.87919928 |
85 | MP0000733_abnormal_muscle_development | 0.84328548 |
86 | MP0002177_abnormal_outer_ear | 0.83461378 |
87 | MP0000428_abnormal_craniofacial_morphol | 0.82901310 |
88 | MP0001849_ear_inflammation | 0.82841907 |
89 | MP0001963_abnormal_hearing_physiology | 0.81340097 |
90 | MP0000013_abnormal_adipose_tissue | 0.80624367 |
91 | MP0000749_muscle_degeneration | 0.77468839 |
92 | MP0005408_hypopigmentation | 0.77354864 |
93 | MP0009697_abnormal_copulation | 0.76429434 |
94 | MP0003195_calcinosis | 0.76103094 |
95 | MP0003878_abnormal_ear_physiology | 0.73531829 |
96 | MP0005377_hearing/vestibular/ear_phenot | 0.73531829 |
97 | MP0000566_synostosis | 0.72374957 |
98 | MP0002877_abnormal_melanocyte_morpholog | 0.72205934 |
99 | MP0005623_abnormal_meninges_morphology | 0.71445357 |
100 | MP0000372_irregular_coat_pigmentation | 0.70915197 |
101 | MP0001243_abnormal_dermal_layer | 0.68665650 |
102 | MP0005391_vision/eye_phenotype | 0.68298697 |
103 | MP0003861_abnormal_nervous_system | 0.67403011 |
104 | MP0001177_atelectasis | 0.67094221 |
105 | MP0006292_abnormal_olfactory_placode | 0.67059924 |
106 | MP0005595_abnormal_vascular_smooth | 0.66796935 |
107 | MP0003115_abnormal_respiratory_system | 0.66769737 |
108 | MP0002128_abnormal_blood_circulation | 0.65233053 |
109 | MP0001286_abnormal_eye_development | 0.64758134 |
110 | MP0001915_intracranial_hemorrhage | 0.64453146 |
111 | MP0002060_abnormal_skin_morphology | 0.64396044 |
112 | MP0005248_abnormal_Harderian_gland | 0.63989735 |
113 | MP0000462_abnormal_digestive_system | 0.62948354 |
114 | * MP0002081_perinatal_lethality | 0.61792978 |
115 | MP0000955_abnormal_spinal_cord | 0.60965100 |
116 | MP0005076_abnormal_cell_differentiation | 0.60062486 |
117 | MP0003941_abnormal_skin_development | 0.58869233 |
118 | MP0005379_endocrine/exocrine_gland_phen | 0.57440023 |
119 | MP0000534_abnormal_ureter_morphology | 0.56966963 |
120 | MP0000465_gastrointestinal_hemorrhage | 0.54629882 |
121 | MP0003119_abnormal_digestive_system | 0.48129081 |
122 | MP0000026_abnormal_inner_ear | 0.47381955 |
123 | MP0006054_spinal_hemorrhage | 0.46681440 |
124 | MP0002295_abnormal_pulmonary_circulatio | 0.45983077 |
125 | * MP0001943_abnormal_respiration | 0.44965749 |
126 | MP0001340_abnormal_eyelid_morphology | 0.44556978 |
127 | MP0002735_abnormal_chemical_nociception | 0.44191453 |
128 | MP0008775_abnormal_heart_ventricle | 0.44122355 |
129 | MP0009053_abnormal_anal_canal | 0.42932107 |
130 | MP0000516_abnormal_urinary_system | 0.42293930 |
131 | MP0005367_renal/urinary_system_phenotyp | 0.42293930 |
132 | MP0005166_decreased_susceptibility_to | 0.41047998 |
133 | MP0003448_altered_tumor_morphology | 0.39326886 |
134 | MP0005193_abnormal_anterior_eye | 0.38533877 |
135 | MP0002234_abnormal_pharynx_morphology | 0.36431669 |
136 | MP0001175_abnormal_lung_morphology | 0.35582796 |
137 | MP0003950_abnormal_plasma_membrane | 0.32650735 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Irregular epiphyses (HP:0010582) | 8.81073902 |
2 | Small epiphyses (HP:0010585) | 7.08117981 |
3 | Abnormal tarsal ossification (HP:0008369) | 6.47906091 |
4 | * Vitreoretinal degeneration (HP:0000655) | 6.43804888 |
5 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 6.31762348 |
6 | Protrusio acetabuli (HP:0003179) | 6.21128487 |
7 | Flat capital femoral epiphysis (HP:0003370) | 6.00896953 |
8 | Aortic dissection (HP:0002647) | 5.89365652 |
9 | Flat acetabular roof (HP:0003180) | 5.66701579 |
10 | Delayed epiphyseal ossification (HP:0002663) | 5.56377130 |
11 | Genu varum (HP:0002970) | 5.53396242 |
12 | Soft skin (HP:0000977) | 5.35899792 |
13 | * Cupped ribs (HP:0000887) | 5.28228244 |
14 | * Hypoplastic ischia (HP:0003175) | 5.20099373 |
15 | Atrophic scars (HP:0001075) | 4.94734853 |
16 | Neonatal short-limb short stature (HP:0008921) | 4.92579167 |
17 | Metaphyseal cupping (HP:0003021) | 4.92432911 |
18 | Flattened epiphyses (HP:0003071) | 4.88603075 |
19 | Abnormal foot bone ossification (HP:0010675) | 4.82632090 |
20 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 4.67257176 |
21 | Absent epiphyses (HP:0010577) | 4.67257176 |
22 | Abnormality of the vertebral endplates (HP:0005106) | 4.64296428 |
23 | * Abnormality of the ischium (HP:0003174) | 4.57535047 |
24 | Mild short stature (HP:0003502) | 4.55901545 |
25 | Bladder diverticulum (HP:0000015) | 4.36552432 |
26 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 4.35278665 |
27 | Abnormality of dentin (HP:0010299) | 4.26530812 |
28 | Genu recurvatum (HP:0002816) | 4.22781501 |
29 | * Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 4.21022762 |
30 | * Abnormality of femoral epiphyses (HP:0006499) | 4.21022762 |
31 | Peritonitis (HP:0002586) | 4.18891849 |
32 | Vascular tortuosity (HP:0004948) | 4.11756351 |
33 | Short femoral neck (HP:0100864) | 4.09691074 |
34 | Metaphyseal dysplasia (HP:0100255) | 4.02756689 |
35 | Abnormality of the femoral head (HP:0003368) | 4.01840611 |
36 | * Osteoarthritis (HP:0002758) | 3.96952898 |
37 | Irregular vertebral endplates (HP:0003301) | 3.95459573 |
38 | Arterial tortuosity (HP:0005116) | 3.84867653 |
39 | Metaphyseal irregularity (HP:0003025) | 3.83820917 |
40 | Fragile skin (HP:0001030) | 3.77020926 |
41 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 3.74868056 |
42 | Abnormality of the pubic bones (HP:0003172) | 3.67024175 |
43 | Aortic aneurysm (HP:0004942) | 3.63445434 |
44 | Coxa vara (HP:0002812) | 3.58029786 |
45 | Mitral valve prolapse (HP:0001634) | 3.54053539 |
46 | Cervical subluxation (HP:0003308) | 3.43675464 |
47 | Enlarged epiphyses (HP:0010580) | 3.42048748 |
48 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 3.41008735 |
49 | Abnormal vertebral ossification (HP:0100569) | 3.38535378 |
50 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 3.35834907 |
51 | Abnormality of carpal bone ossification (HP:0006257) | 3.34628284 |
52 | Infantile muscular hypotonia (HP:0008947) | 3.32280739 |
53 | Morphological abnormality of the middle ear (HP:0008609) | 3.31405403 |
54 | * Wide anterior fontanel (HP:0000260) | 3.23454813 |
55 | Bowel diverticulosis (HP:0005222) | 3.17491016 |
56 | Shallow orbits (HP:0000586) | 3.15527080 |
57 | Thoracolumbar scoliosis (HP:0002944) | 3.13410256 |
58 | Barrel-shaped chest (HP:0001552) | 3.11360575 |
59 | Waddling gait (HP:0002515) | 3.10156824 |
60 | Limited elbow extension (HP:0001377) | 3.09418433 |
61 | Beaking of vertebral bodies (HP:0004568) | 3.06289746 |
62 | * Platyspondyly (HP:0000926) | 3.04929200 |
63 | Vertebral clefting (HP:0008428) | 3.03324647 |
64 | Hyperextensible skin (HP:0000974) | 2.98938879 |
65 | Ovoid vertebral bodies (HP:0003300) | 2.97746413 |
66 | Biconcave vertebral bodies (HP:0004586) | 2.96306635 |
67 | Aplasia/hypoplasia of the femur (HP:0005613) | 2.94684425 |
68 | Wormian bones (HP:0002645) | 2.87717704 |
69 | Spondylolisthesis (HP:0003302) | 2.87603739 |
70 | Exostoses (HP:0100777) | 2.87238143 |
71 | Dilatation of the ascending aorta (HP:0005111) | 2.87176322 |
72 | Blue sclerae (HP:0000592) | 2.86067426 |
73 | Broad metatarsal (HP:0001783) | 2.86057817 |
74 | Limited hip movement (HP:0008800) | 2.83676247 |
75 | Cerebral aneurysm (HP:0004944) | 2.81590931 |
76 | Breech presentation (HP:0001623) | 2.78998355 |
77 | Abnormal hand bone ossification (HP:0010660) | 2.74202967 |
78 | Glossoptosis (HP:0000162) | 2.70321879 |
79 | Hip contracture (HP:0003273) | 2.68005927 |
80 | Hypoplasia of the iris (HP:0007676) | 2.65903363 |
81 | Lumbar hyperlordosis (HP:0002938) | 2.65724400 |
82 | Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 2.65532838 |
83 | Abnormal ossification of hand bones (HP:0005921) | 2.65457270 |
84 | Abnormal delivery (HP:0001787) | 2.65003952 |
85 | Carpal bone hypoplasia (HP:0001498) | 2.62716495 |
86 | Hypoplasia of the odontoid process (HP:0003311) | 2.61750650 |
87 | Spinal cord compression (HP:0002176) | 2.55540929 |
88 | Tibial bowing (HP:0002982) | 2.52168060 |
89 | Mesomelia (HP:0003027) | 2.51592197 |
90 | Ankle contracture (HP:0006466) | 2.48901132 |
91 | Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376) | 2.48467048 |
92 | Hypoplastic pelvis (HP:0008839) | 2.43332521 |
93 | Abnormality of the lumbar spine (HP:0100712) | 2.42068115 |
94 | Aortic regurgitation (HP:0001659) | 2.41677357 |
95 | Calcaneovalgus deformity (HP:0001848) | 2.41548180 |
96 | Follicular hyperkeratosis (HP:0007502) | 2.40471752 |
97 | Joint laxity (HP:0001388) | 2.38252348 |
98 | Abnormality of the 2nd finger (HP:0004100) | 2.37755507 |
99 | * Arthropathy (HP:0003040) | 2.35047346 |
100 | * Protuberant abdomen (HP:0001538) | 2.33532633 |
101 | Decreased skull ossification (HP:0004331) | 2.31209155 |
102 | Deformed tarsal bones (HP:0008119) | 2.29367480 |
103 | Abnormality of the acetabulum (HP:0003170) | 2.28647826 |
104 | Disproportionate short-trunk short stature (HP:0003521) | 2.27808016 |
105 | Abnormality of the phalanges of the 5th finger (HP:0004213) | 2.24976094 |
106 | Mitral regurgitation (HP:0001653) | 2.24791287 |
107 | * Ectopia lentis (HP:0001083) | 2.24486911 |
108 | Coronal craniosynostosis (HP:0004440) | 2.23652109 |
109 | Short middle phalanx of finger (HP:0005819) | 2.22770270 |
110 | Short 4th metacarpal (HP:0010044) | 2.21937313 |
111 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 2.21937313 |
112 | Abnormality of the odontoid process (HP:0003310) | 2.18671326 |
113 | Overgrowth (HP:0001548) | 2.18219552 |
114 | Mixed hearing impairment (HP:0000410) | 2.18194673 |
115 | Femoral bowing (HP:0002980) | 2.18187205 |
116 | * Micromelia (HP:0002983) | 2.16025830 |
117 | Relative macrocephaly (HP:0004482) | 2.12666970 |
118 | Flared metaphyses (HP:0003015) | 2.10255617 |
119 | Increased corneal curvature (HP:0100692) | 2.09236178 |
120 | Keratoconus (HP:0000563) | 2.09236178 |
121 | Deviation of the hallux (HP:0010051) | 2.08415978 |
122 | Abnormality of the calcaneus (HP:0008364) | 2.08410377 |
123 | Abnormality of skull ossification (HP:0002703) | 2.08009064 |
124 | Severe Myopia (HP:0011003) | 2.07162578 |
125 | Cone-shaped epiphyses of the phalanges of the hand (HP:0010230) | 2.01986740 |
126 | * Absent frontal sinuses (HP:0002688) | 2.01745804 |
127 | * Abnormality of the vitreous humor (HP:0004327) | 2.01227295 |
128 | Nonimmune hydrops fetalis (HP:0001790) | 2.00744085 |
129 | Epiphyseal dysplasia (HP:0002656) | 10.5941330 |
130 | Hallux valgus (HP:0001822) | 1.98233799 |
131 | Broad thumb (HP:0011304) | 1.98089686 |
132 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.97103576 |
133 | * Stillbirth (HP:0003826) | 1.95279035 |
134 | Inguinal hernia (HP:0000023) | 1.94938323 |
135 | Type 1 muscle fiber predominance (HP:0003803) | 1.94724807 |
136 | Turricephaly (HP:0000262) | 1.91013521 |
137 | Joint stiffness (HP:0001387) | 1.90259135 |
138 | Broad ribs (HP:0000885) | 1.89975066 |
139 | Aplasia/Hypoplasia of the middle phalanges of the hand (HP:0009843) | 1.84654661 |
140 | Venous insufficiency (HP:0005293) | 1.84414896 |
141 | Abnormality of the middle phalanges of the hand (HP:0009833) | 1.83574002 |
142 | Broad phalanges of the hand (HP:0009768) | 1.80811577 |
143 | Tracheomalacia (HP:0002779) | 1.79915463 |
144 | Delayed gross motor development (HP:0002194) | 1.79889174 |
145 | Abnormal cartilage morphology (HP:0002763) | 1.79451244 |
146 | Partial duplication of the phalanx of hand (HP:0009999) | 1.79126402 |
147 | Cutaneous finger syndactyly (HP:0010554) | 1.78878548 |
148 | Abnormality of the epiphyses of the phalanges of the hand (HP:0005920) | 1.78124276 |
149 | Renal duplication (HP:0000075) | 1.77671670 |
150 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.76472095 |
151 | * Broad phalanx (HP:0006009) | 1.75729232 |
152 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 1.74945318 |
153 | * Genu valgum (HP:0002857) | 1.74791445 |
154 | Abnormality of the wing of the ilium (HP:0011867) | 1.74394959 |
155 | Broad finger (HP:0001500) | 1.74340576 |
156 | * Thin ribs (HP:0000883) | 1.73918842 |
157 | * Broad long bones (HP:0005622) | 1.71930517 |
158 | * Ulnar bowing (HP:0003031) | 1.69548826 |
159 | Premature rupture of membranes (HP:0001788) | 1.69308910 |
160 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.68021683 |
161 | Osteolytic defects of the hand bones (HP:0009699) | 1.68021683 |
162 | Short 5th finger (HP:0009237) | 1.67999667 |
163 | Camptodactyly of toe (HP:0001836) | 1.67376446 |
164 | Spinal rigidity (HP:0003306) | 1.66628320 |
165 | Hypoplastic iliac wings (HP:0002866) | 1.66186349 |
166 | Bifid tongue (HP:0010297) | 1.65224796 |
167 | Vertebral arch anomaly (HP:0008438) | 1.64092127 |
168 | * Hypoplastic ilia (HP:0000946) | 1.62707399 |
169 | Disproportionate tall stature (HP:0001519) | 1.62289959 |
170 | Cutaneous syndactyly (HP:0012725) | 1.62217523 |
171 | Renovascular hypertension (HP:0100817) | 1.60031232 |
172 | Delayed cranial suture closure (HP:0000270) | 1.59760518 |
173 | Mitral stenosis (HP:0001718) | 1.59545878 |
174 | Abnormality of the 4th metacarpal (HP:0010012) | 1.57777422 |
175 | Pulmonary artery stenosis (HP:0004415) | 1.56149959 |
176 | Syringomyelia (HP:0003396) | 1.53687943 |
177 | Spinal cord lesions (HP:0100561) | 1.53687943 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DDR2 | 8.91211264 |
2 | MAP3K3 | 6.88827034 |
3 | STK38L | 4.46827397 |
4 | STK24 | 4.05462538 |
5 | NME1 | 3.92428735 |
6 | PRKG2 | 3.58530204 |
7 | TNIK | 3.57503505 |
8 | NTRK1 | 3.47323782 |
9 | PDGFRA | 3.35791109 |
10 | ERBB3 | 2.62429590 |
11 | MST4 | 2.53483847 |
12 | MARK1 | 2.34904744 |
13 | MYLK | 2.19574182 |
14 | CASK | 2.16752043 |
15 | PNCK | 2.08618572 |
16 | PRKD3 | 2.06359479 |
17 | PLK2 | 2.01191802 |
18 | LATS1 | 1.96601249 |
19 | SIK1 | 1.65291386 |
20 | TRPM7 | 1.61291622 |
21 | STK3 | 1.58595739 |
22 | NUAK1 | 1.57704763 |
23 | MKNK2 | 1.54432355 |
24 | DYRK1A | 1.50204323 |
25 | FLT3 | 1.41526978 |
26 | NTRK2 | 1.39846761 |
27 | MOS | 1.28779197 |
28 | FGFR2 | 1.27312686 |
29 | CAMK1G | 1.19567493 |
30 | PAK6 | 1.14587763 |
31 | TAOK1 | 1.13465270 |
32 | EPHB2 | 1.11863528 |
33 | PIM2 | 1.09710496 |
34 | TYRO3 | 1.08300473 |
35 | NEK6 | 1.08270964 |
36 | PIK3CA | 1.07530188 |
37 | EIF2AK3 | 1.07466738 |
38 | ROCK1 | 1.01005341 |
39 | PAK4 | 1.00791841 |
40 | MAPK7 | 0.98711509 |
41 | PDK2 | 0.97674013 |
42 | MAPK12 | 0.97185220 |
43 | EPHA2 | 0.95671378 |
44 | WEE1 | 0.95275479 |
45 | DMPK | 0.94847765 |
46 | MKNK1 | 0.93259776 |
47 | NME2 | 0.92069469 |
48 | MET | 0.91929780 |
49 | CSNK1G2 | 0.91364308 |
50 | MAP3K10 | 0.91326628 |
51 | CAMKK2 | 0.90878769 |
52 | BMPR1B | 0.84546694 |
53 | TIE1 | 0.84167705 |
54 | GSK3A | 0.79862573 |
55 | MAP3K6 | 0.74855275 |
56 | BRD4 | 0.74267717 |
57 | AKT3 | 0.72365609 |
58 | PIK3CG | 0.69773593 |
59 | RIPK1 | 0.69352709 |
60 | TRIB3 | 0.68873535 |
61 | MAPK4 | 0.66064327 |
62 | NEK2 | 0.62438043 |
63 | ERBB2 | 0.60488036 |
64 | BCR | 0.58618137 |
65 | FGFR1 | 0.57445230 |
66 | STK38 | 0.55371045 |
67 | CDK6 | 0.54962184 |
68 | PLK3 | 0.54295190 |
69 | LIMK1 | 0.54195344 |
70 | WNK4 | 0.53563095 |
71 | EIF2AK1 | 0.53206129 |
72 | TAOK2 | 0.52963743 |
73 | TGFBR1 | 0.52203587 |
74 | CDK18 | 0.47948426 |
75 | LATS2 | 0.46287370 |
76 | DYRK2 | 0.46262178 |
77 | MAPK15 | 0.46141414 |
78 | CDK15 | 0.46071046 |
79 | WNK1 | 0.45160027 |
80 | CDK11A | 0.44762297 |
81 | MAP2K3 | 0.43891182 |
82 | CDK3 | 0.43536645 |
83 | LMTK2 | 0.43381042 |
84 | EPHA3 | 0.42953765 |
85 | FGFR3 | 0.42784591 |
86 | PRKCH | 0.42552611 |
87 | DYRK1B | 0.41304065 |
88 | CDC42BPA | 0.40154647 |
89 | MAP3K4 | 0.39516141 |
90 | MINK1 | 0.39187537 |
91 | CDK14 | 0.39168554 |
92 | NLK | 0.38763705 |
93 | PBK | 0.38127580 |
94 | UHMK1 | 0.37792565 |
95 | MAP3K11 | 0.37509239 |
96 | YES1 | 0.37470340 |
97 | CDK12 | 0.36363032 |
98 | STK39 | 0.36356570 |
99 | EPHA4 | 0.35933277 |
100 | SRC | 0.35806673 |
101 | MUSK | 0.35514345 |
102 | EIF2AK2 | 0.35352491 |
103 | PTK2B | 0.34854624 |
104 | RPS6KA2 | 0.34348290 |
105 | FER | 0.33567023 |
106 | CAMKK1 | 0.33302991 |
107 | PAK3 | 0.32479750 |
108 | PRKG1 | 0.31854062 |
109 | KSR1 | 0.31835698 |
110 | PKN2 | 0.29785922 |
111 | PTK2 | 0.29619436 |
112 | PRKD2 | 0.28210043 |
113 | PDGFRB | 0.27535047 |
114 | ERBB4 | 0.27449898 |
115 | TGFBR2 | 0.26988404 |
116 | PRKACG | 0.26221459 |
117 | CSNK1A1L | 0.25825384 |
118 | PRKCE | 0.25381164 |
119 | TTN | 0.25144394 |
120 | CSNK1G1 | 0.25017972 |
121 | RPS6KB1 | 0.24986034 |
122 | TESK1 | 0.24872667 |
123 | IGF1R | 0.24558815 |
124 | CSF1R | 0.23459807 |
125 | BMX | 0.23323186 |
126 | BRSK2 | 0.23290139 |
127 | ADRBK1 | 0.22653480 |
128 | MAPK10 | 0.21468063 |
129 | ABL1 | 0.20788332 |
130 | SGK1 | 0.20342158 |
131 | PRKCD | 0.20330076 |
132 | MAPK1 | 0.19589159 |
133 | PIM1 | 0.19574658 |
134 | MAPK3 | 0.19477986 |
135 | PAK2 | 0.19356020 |
136 | PRKCI | 0.16960116 |
137 | INSR | 0.16565315 |
138 | ROCK2 | 0.14436823 |
139 | MAP3K5 | 0.13069587 |
140 | NEK9 | 0.12806430 |
141 | PRKACA | 0.12176744 |
142 | BMPR2 | 0.11704602 |
143 | SIK3 | 0.10533773 |
144 | CHUK | 0.09181734 |
145 | IKBKB | 0.08726134 |
146 | MTOR | 0.08709936 |
147 | AKT1 | 0.08405640 |
148 | PRKCG | 0.08250899 |
149 | PRKCA | 0.07850917 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 7.48860772 |
2 | ECM-receptor interaction_Homo sapiens_hsa04512 | 6.72148421 |
3 | * Protein digestion and absorption_Homo sapiens_hsa04974 | 5.35874720 |
4 | Focal adhesion_Homo sapiens_hsa04510 | 2.63885179 |
5 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.50322638 |
6 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 2.45890094 |
7 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 2.38769951 |
8 | Sulfur metabolism_Homo sapiens_hsa00920 | 2.26851233 |
9 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.92465295 |
10 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.86892200 |
11 | Malaria_Homo sapiens_hsa05144 | 1.81287936 |
12 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.78148734 |
13 | Olfactory transduction_Homo sapiens_hsa04740 | 1.72397807 |
14 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.54935578 |
15 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 1.46918971 |
16 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.38822403 |
17 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.36708458 |
18 | Protein export_Homo sapiens_hsa03060 | 1.36565069 |
19 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.36485700 |
20 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.35241217 |
21 | Other glycan degradation_Homo sapiens_hsa00511 | 1.31922174 |
22 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.31809723 |
23 | Tight junction_Homo sapiens_hsa04530 | 1.27777193 |
24 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.27278056 |
25 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.25417834 |
26 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.20795562 |
27 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.17403869 |
28 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.16645641 |
29 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 1.05238099 |
30 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.04769119 |
31 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.01792775 |
32 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.00822149 |
33 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.97881037 |
34 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.97231902 |
35 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.95168902 |
36 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.86299875 |
37 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.84619882 |
38 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 0.81744560 |
39 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.78596729 |
40 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.78052482 |
41 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.77880078 |
42 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.75019838 |
43 | Endometrial cancer_Homo sapiens_hsa05213 | 0.74991518 |
44 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.74634754 |
45 | Phagosome_Homo sapiens_hsa04145 | 0.74592612 |
46 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.74485543 |
47 | Long-term depression_Homo sapiens_hsa04730 | 0.71576581 |
48 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.71137986 |
49 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.68229550 |
50 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.66580526 |
51 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.64998979 |
52 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.62677024 |
53 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.62092875 |
54 | Salivary secretion_Homo sapiens_hsa04970 | 0.61500974 |
55 | Adherens junction_Homo sapiens_hsa04520 | 0.60847530 |
56 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.58926357 |
57 | Gap junction_Homo sapiens_hsa04540 | 0.58698100 |
58 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.58563979 |
59 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.58309545 |
60 | Melanogenesis_Homo sapiens_hsa04916 | 0.57016721 |
61 | Bladder cancer_Homo sapiens_hsa05219 | 0.56606569 |
62 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 0.54684867 |
63 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.54571809 |
64 | Amoebiasis_Homo sapiens_hsa05146 | 0.54436946 |
65 | Nicotine addiction_Homo sapiens_hsa05033 | 0.53701602 |
66 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.53423508 |
67 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.53121300 |
68 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.51907263 |
69 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.51333236 |
70 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.49865920 |
71 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.49449420 |
72 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.49340638 |
73 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.48693559 |
74 | Circadian entrainment_Homo sapiens_hsa04713 | 0.48037049 |
75 | Galactose metabolism_Homo sapiens_hsa00052 | 0.47987451 |
76 | Lysine degradation_Homo sapiens_hsa00310 | 0.46665832 |
77 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.46600811 |
78 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.46481857 |
79 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.46479713 |
80 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.46022090 |
81 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.46003598 |
82 | Axon guidance_Homo sapiens_hsa04360 | 0.45966288 |
83 | Prostate cancer_Homo sapiens_hsa05215 | 0.43300774 |
84 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.43247823 |
85 | Circadian rhythm_Homo sapiens_hsa04710 | 0.41197627 |
86 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.41060502 |
87 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.40599630 |
88 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.39392718 |
89 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.36867881 |
90 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.36439189 |
91 | Platelet activation_Homo sapiens_hsa04611 | 0.36005830 |
92 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.35655027 |
93 | Cocaine addiction_Homo sapiens_hsa05030 | 0.35544873 |
94 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.34972117 |
95 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.34861730 |
96 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.34696954 |
97 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.34495245 |
98 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.33167605 |
99 | Prion diseases_Homo sapiens_hsa05020 | 0.32565938 |
100 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.31915731 |
101 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.31843214 |
102 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.31448795 |
103 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.30527183 |
104 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.30521969 |
105 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.30136359 |
106 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.30135699 |
107 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.30031844 |
108 | Melanoma_Homo sapiens_hsa05218 | 0.29662698 |
109 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.29592336 |
110 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.29497836 |
111 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.29367729 |
112 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.28957980 |
113 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.28928272 |
114 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.28434380 |
115 | HTLV-I infection_Homo sapiens_hsa05166 | 0.28256698 |
116 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.28077161 |
117 | Glioma_Homo sapiens_hsa05214 | 0.27793271 |
118 | Thyroid cancer_Homo sapiens_hsa05216 | 0.27723834 |
119 | Hepatitis B_Homo sapiens_hsa05161 | 0.27669152 |
120 | Pathways in cancer_Homo sapiens_hsa05200 | 0.27517513 |
121 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.27220456 |
122 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.27110990 |
123 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.26015996 |
124 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.25739330 |
125 | Taste transduction_Homo sapiens_hsa04742 | 0.24938272 |
126 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.24570930 |
127 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.24048516 |
128 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.22159713 |
129 | Renin secretion_Homo sapiens_hsa04924 | 0.20999532 |
130 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.19343707 |
131 | Colorectal cancer_Homo sapiens_hsa05210 | 0.19294244 |
132 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.18325046 |
133 | Insulin resistance_Homo sapiens_hsa04931 | 0.18176554 |
134 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.17662819 |
135 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.17164684 |