Rank | Gene Set | Z-score |
---|---|---|
1 | glomerular basement membrane development (GO:0032836) | 5.17863563 |
2 | glomerular visceral epithelial cell development (GO:0072015) | 4.60206316 |
3 | collagen fibril organization (GO:0030199) | 4.43434160 |
4 | lateral sprouting from an epithelium (GO:0060601) | 4.42173172 |
5 | protein heterotrimerization (GO:0070208) | 4.41456266 |
6 | cell adhesion mediated by integrin (GO:0033627) | 4.31003898 |
7 | glomerular epithelial cell development (GO:0072310) | 4.30001757 |
8 | epithelial cell-cell adhesion (GO:0090136) | 4.21272939 |
9 | plasma membrane repair (GO:0001778) | 4.13554969 |
10 | notochord development (GO:0030903) | 3.96746016 |
11 | chondrocyte proliferation (GO:0035988) | 3.94114779 |
12 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.91551582 |
13 | endodermal cell differentiation (GO:0035987) | 3.90552864 |
14 | cardiac myofibril assembly (GO:0055003) | 3.89668345 |
15 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.85591681 |
16 | axon extension involved in axon guidance (GO:0048846) | 3.85591681 |
17 | basement membrane organization (GO:0071711) | 3.85085692 |
18 | kidney mesenchyme development (GO:0072074) | 3.75269525 |
19 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 3.60771745 |
20 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 3.59222427 |
21 | hippo signaling (GO:0035329) | 3.57322214 |
22 | wound healing, spreading of epidermal cells (GO:0035313) | 3.54374142 |
23 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.52852840 |
24 | convergent extension (GO:0060026) | 3.52095611 |
25 | regulation of establishment of planar polarity (GO:0090175) | 3.49491605 |
26 | vascular endothelial growth factor signaling pathway (GO:0038084) | 3.42918734 |
27 | sarcomere organization (GO:0045214) | 3.42417769 |
28 | wound healing, spreading of cells (GO:0044319) | 3.41020823 |
29 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.40161915 |
30 | regulation of transforming growth factor beta2 production (GO:0032909) | 3.37919885 |
31 | renal filtration (GO:0097205) | 3.37423691 |
32 | * collagen metabolic process (GO:0032963) | 3.37281273 |
33 | pattern specification involved in kidney development (GO:0061004) | 3.35115221 |
34 | cell migration involved in sprouting angiogenesis (GO:0002042) | 3.33301269 |
35 | non-canonical Wnt signaling pathway (GO:0035567) | 3.32582875 |
36 | * collagen catabolic process (GO:0030574) | 3.30143499 |
37 | limb bud formation (GO:0060174) | 3.29152081 |
38 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.28715922 |
39 | hemidesmosome assembly (GO:0031581) | 3.28149289 |
40 | skin morphogenesis (GO:0043589) | 3.25975488 |
41 | embryonic foregut morphogenesis (GO:0048617) | 3.25699614 |
42 | * multicellular organismal macromolecule metabolic process (GO:0044259) | 3.23648120 |
43 | endocardial cushion development (GO:0003197) | 3.21367305 |
44 | atrioventricular valve morphogenesis (GO:0003181) | 3.21279524 |
45 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.20162711 |
46 | branching involved in salivary gland morphogenesis (GO:0060445) | 3.19536968 |
47 | regulation of cardioblast differentiation (GO:0051890) | 3.19329561 |
48 | bone trabecula formation (GO:0060346) | 3.15920640 |
49 | regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095) | 3.15860643 |
50 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.15645118 |
51 | apical protein localization (GO:0045176) | 3.14432938 |
52 | cell surface receptor signaling pathway involved in heart development (GO:0061311) | 3.13706984 |
53 | regulation of non-canonical Wnt signaling pathway (GO:2000050) | 3.13477717 |
54 | epoxygenase P450 pathway (GO:0019373) | 3.12522969 |
55 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.12270273 |
56 | * multicellular organismal catabolic process (GO:0044243) | 3.10633767 |
57 | lymph vessel development (GO:0001945) | 3.09871063 |
58 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 3.06483777 |
59 | myofibril assembly (GO:0030239) | 3.06060614 |
60 | * multicellular organismal metabolic process (GO:0044236) | 3.05565862 |
61 | negative regulation of fatty acid transport (GO:2000192) | 3.05053601 |
62 | metanephric mesenchyme development (GO:0072075) | 3.00340734 |
63 | mesenchymal cell proliferation (GO:0010463) | 3.00242295 |
64 | atrial septum morphogenesis (GO:0060413) | 2.98727911 |
65 | * extracellular matrix disassembly (GO:0022617) | 2.97915775 |
66 | gap junction assembly (GO:0016264) | 2.97787009 |
67 | negative regulation of cardiac muscle cell apoptotic process (GO:0010667) | 2.97439532 |
68 | regulation of hippo signaling (GO:0035330) | 2.96883996 |
69 | mesodermal cell differentiation (GO:0048333) | 2.94481372 |
70 | regulation of branching involved in prostate gland morphogenesis (GO:0060687) | 2.94033065 |
71 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 2.93702134 |
72 | cell-substrate junction assembly (GO:0007044) | 2.93628475 |
73 | stress fiber assembly (GO:0043149) | 2.91664864 |
74 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.90822159 |
75 | polarized epithelial cell differentiation (GO:0030859) | 2.86727755 |
76 | endothelial cell morphogenesis (GO:0001886) | 2.86475325 |
77 | craniofacial suture morphogenesis (GO:0097094) | 2.84779593 |
78 | establishment of apical/basal cell polarity (GO:0035089) | 2.84731899 |
79 | endothelial cell chemotaxis (GO:0035767) | 2.84574102 |
80 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.84419929 |
81 | glomerular filtration (GO:0003094) | 2.83986918 |
82 | actomyosin structure organization (GO:0031032) | 2.83711134 |
83 | dorsal/ventral axis specification (GO:0009950) | 2.83149470 |
84 | lung-associated mesenchyme development (GO:0060484) | 2.80502537 |
85 | negative regulation of axon guidance (GO:1902668) | 2.80148624 |
86 | cellular response to vitamin (GO:0071295) | 2.79481615 |
87 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 2.77044814 |
88 | lymphangiogenesis (GO:0001946) | 2.76996900 |
89 | apoptotic cell clearance (GO:0043277) | 2.76690671 |
90 | artery development (GO:0060840) | 2.76553646 |
91 | negative chemotaxis (GO:0050919) | 2.75805543 |
92 | cell proliferation involved in metanephros development (GO:0072203) | 2.75236510 |
93 | embryonic retina morphogenesis in camera-type eye (GO:0060059) | 2.72242659 |
94 | camera-type eye morphogenesis (GO:0048593) | 2.71931702 |
95 | mesenchymal-epithelial cell signaling (GO:0060638) | 2.71927778 |
96 | midgut development (GO:0007494) | 2.71773316 |
97 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.70902980 |
98 | adherens junction assembly (GO:0034333) | 2.70071443 |
99 | protein localization to cell surface (GO:0034394) | 2.69657050 |
100 | positive regulation of extracellular matrix organization (GO:1903055) | 2.69247058 |
101 | regulation of heart morphogenesis (GO:2000826) | 2.68893754 |
102 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.68450275 |
103 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.68411060 |
104 | asymmetric protein localization (GO:0008105) | 2.68381793 |
105 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 2.68375086 |
106 | negative regulation of axon extension involved in axon guidance (GO:0048843) | 2.67785778 |
107 | axis elongation (GO:0003401) | 2.67182672 |
108 | tongue development (GO:0043586) | 2.67010521 |
109 | cellular response to vitamin D (GO:0071305) | 2.66806106 |
110 | mesenchyme morphogenesis (GO:0072132) | 2.65470813 |
111 | negative regulation of striated muscle cell apoptotic process (GO:0010664) | 2.63965924 |
112 | trabecula formation (GO:0060343) | 2.63902627 |
113 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.63772084 |
114 | desmosome organization (GO:0002934) | 2.62984162 |
115 | cardiac muscle cell proliferation (GO:0060038) | 2.62521190 |
116 | presynaptic membrane assembly (GO:0097105) | 2.62165200 |
117 | prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis (GO:006052 | 2.61798255 |
118 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.60527664 |
119 | mesenchyme development (GO:0060485) | 2.60224805 |
120 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.59636756 |
121 | paraxial mesoderm development (GO:0048339) | 2.59414065 |
122 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.59135120 |
123 | blood vessel endothelial cell migration (GO:0043534) | 2.59124842 |
124 | cochlea morphogenesis (GO:0090103) | 2.58762489 |
125 | radial glial cell differentiation (GO:0060019) | 2.58753871 |
126 | heart trabecula formation (GO:0060347) | 2.58255778 |
127 | positive regulation of catenin import into nucleus (GO:0035413) | 2.56419755 |
128 | fibroblast migration (GO:0010761) | 2.56134373 |
129 | regulation of tight junction assembly (GO:2000810) | 2.55364026 |
130 | * extracellular matrix organization (GO:0030198) | 2.54388383 |
131 | establishment of monopolar cell polarity (GO:0061162) | 2.54082514 |
132 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.54082514 |
133 | * extracellular structure organization (GO:0043062) | 2.53260689 |
134 | positive regulation of mesenchymal cell proliferation (GO:0002053) | 2.53238949 |
135 | glomerulus development (GO:0032835) | 2.53121300 |
136 | negative regulation of cell fate specification (GO:0009996) | 2.52667334 |
137 | heart morphogenesis (GO:0003007) | 2.51836753 |
138 | lens fiber cell development (GO:0070307) | 2.51335668 |
139 | otic vesicle formation (GO:0030916) | 2.51168591 |
140 | positive regulation of canonical Wnt signaling pathway (GO:0090263) | 2.50670877 |
141 | germ cell migration (GO:0008354) | 2.49955236 |
142 | morphogenesis of an epithelial sheet (GO:0002011) | 2.49555233 |
143 | negative regulation of potassium ion transmembrane transporter activity (GO:1901017) | 2.49094545 |
144 | regulation of axon guidance (GO:1902667) | 2.48673141 |
145 | establishment of planar polarity (GO:0001736) | 2.48517822 |
146 | establishment of tissue polarity (GO:0007164) | 2.48517822 |
147 | omega-hydroxylase P450 pathway (GO:0097267) | 2.47835852 |
148 | endocardial cushion morphogenesis (GO:0003203) | 2.42934562 |
149 | positive regulation of smoothened signaling pathway (GO:0045880) | 2.40399568 |
150 | neuronal stem cell maintenance (GO:0097150) | 2.39971231 |
151 | establishment of nucleus localization (GO:0040023) | 2.38998367 |
152 | negative regulation of cartilage development (GO:0061037) | 2.37704582 |
153 | myoblast fusion (GO:0007520) | 2.36182366 |
154 | digestive tract morphogenesis (GO:0048546) | 2.35029731 |
155 | cranial suture morphogenesis (GO:0060363) | 2.34999067 |
156 | post-anal tail morphogenesis (GO:0036342) | 2.33504126 |
157 | mesenchymal cell differentiation (GO:0048762) | 2.33035537 |
158 | renal system development (GO:0072001) | 2.32344846 |
159 | gastrulation with mouth forming second (GO:0001702) | 2.31530681 |
160 | neural crest cell development (GO:0014032) | 2.30077144 |
161 | muscle cell proliferation (GO:0033002) | 2.27659673 |
162 | genitalia morphogenesis (GO:0035112) | 2.27640550 |
163 | outflow tract septum morphogenesis (GO:0003148) | 2.27172903 |
164 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 2.26605546 |
165 | positive regulation of cardiac muscle tissue development (GO:0055025) | 2.26500200 |
166 | midbrain development (GO:0030901) | 2.26310283 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 5.56969991 |
2 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 5.17895028 |
3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.82760848 |
4 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 3.37782008 |
5 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 3.04762002 |
6 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.97317189 |
7 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.93406841 |
8 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 2.40741117 |
9 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 2.40187313 |
10 | EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.37252729 |
11 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.24212718 |
12 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.20268839 |
13 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 2.19517811 |
14 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.16433367 |
15 | CJUN_26792858_Chip-Seq_BT549_Human | 2.14521701 |
16 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.13423695 |
17 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.99655873 |
18 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.96670222 |
19 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.93013966 |
20 | * WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.92457775 |
21 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.88174437 |
22 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.85394611 |
23 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.78112549 |
24 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.76965448 |
25 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 1.75794792 |
26 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.73913614 |
27 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.73165777 |
28 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.70069036 |
29 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.67423863 |
30 | TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.67212302 |
31 | TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.67212302 |
32 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.62205682 |
33 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.60935465 |
34 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.60094276 |
35 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.60094276 |
36 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.60089540 |
37 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.58630722 |
38 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.56397534 |
39 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.55350811 |
40 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.54859188 |
41 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.54859188 |
42 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.54038374 |
43 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.53020085 |
44 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.53020085 |
45 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.52790546 |
46 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.51188437 |
47 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.49758341 |
48 | TP53_16413492_ChIP-PET_HCT116_Human | 1.49390290 |
49 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.48808992 |
50 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.46009222 |
51 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.43852821 |
52 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.42431049 |
53 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.41035305 |
54 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 1.40330783 |
55 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.40160720 |
56 | * YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.38457798 |
57 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.38218768 |
58 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.38137747 |
59 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.38099610 |
60 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.37900852 |
61 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.37823245 |
62 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.36896335 |
63 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.36441859 |
64 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.35408189 |
65 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.34534232 |
66 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.34279613 |
67 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.33901971 |
68 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.33316820 |
69 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.32977813 |
70 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.32384038 |
71 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.32326011 |
72 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.30962433 |
73 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.30746325 |
74 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.29125750 |
75 | SOX2_20726797_ChIP-Seq_SW620_Human | 1.28710208 |
76 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.27832244 |
77 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.27381303 |
78 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.26927635 |
79 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.26672171 |
80 | SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.26034414 |
81 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.25888334 |
82 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.25688258 |
83 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.25186773 |
84 | FUS_26573619_Chip-Seq_HEK293_Human | 1.24176551 |
85 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.23339833 |
86 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.23234374 |
87 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.22527437 |
88 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.22474359 |
89 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.22421738 |
90 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.22067995 |
91 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.21449394 |
92 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.21418481 |
93 | JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.21229272 |
94 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.20705637 |
95 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.20695519 |
96 | DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.19921073 |
97 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.19670825 |
98 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.19364051 |
99 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.18273235 |
100 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.18250088 |
101 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.16918397 |
102 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.15690071 |
103 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.15129813 |
104 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.14783898 |
105 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.14507383 |
106 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.11564472 |
107 | TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.10211305 |
108 | SOX9_26525672_Chip-Seq_HEART_Mouse | 1.10083991 |
109 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.09631331 |
110 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.08791136 |
111 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.08722201 |
112 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.08346605 |
113 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.08309114 |
114 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.08283196 |
115 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.08283196 |
116 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.08283196 |
117 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.08051438 |
118 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.07600213 |
119 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.07394578 |
120 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 1.06943060 |
121 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.06751411 |
122 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.06322717 |
123 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.05652533 |
124 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.05256067 |
125 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.04999003 |
126 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.04906934 |
127 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.04608262 |
128 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 1.03765810 |
129 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.03230344 |
130 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.03143670 |
131 | JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.02936903 |
132 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.02854241 |
133 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.02774271 |
134 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.02419905 |
135 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.01834426 |
136 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.01755384 |
137 | LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.01708332 |
138 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.01675839 |
139 | ATF3_27146783_Chip-Seq_COLON_Human | 1.01484531 |
140 | KDM2B_26808549_Chip-Seq_K562_Human | 1.00474727 |
141 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.00409402 |
142 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.00107429 |
143 | * TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.99408471 |
144 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 0.98667791 |
145 | RXR_22108803_ChIP-Seq_LS180_Human | 0.98626905 |
146 | KLF5_25053715_ChIP-Seq_YYC3_Human | 0.97783817 |
147 | SMAD3_21741376_ChIP-Seq_HESCs_Human | 0.97736742 |
148 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 0.96909807 |
149 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 0.96353677 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 5.67691151 |
2 | MP0000566_synostosis | 4.54694590 |
3 | MP0005275_abnormal_skin_tensile | 3.84724163 |
4 | MP0004272_abnormal_basement_membrane | 3.68113072 |
5 | MP0005623_abnormal_meninges_morphology | 3.67495376 |
6 | MP0005503_abnormal_tendon_morphology | 3.45984980 |
7 | MP0000579_abnormal_nail_morphology | 3.34110726 |
8 | MP0003705_abnormal_hypodermis_morpholog | 3.22240259 |
9 | MP0003279_aneurysm | 2.95769142 |
10 | MP0001958_emphysema | 2.82665833 |
11 | MP0004084_abnormal_cardiac_muscle | 2.78913648 |
12 | MP0009384_cardiac_valve_regurgitation | 2.64191519 |
13 | MP0003566_abnormal_cell_adhesion | 2.14506835 |
14 | MP0006054_spinal_hemorrhage | 2.08973690 |
15 | MP0000751_myopathy | 1.82400919 |
16 | MP0003385_abnormal_body_wall | 1.80241580 |
17 | MP0003941_abnormal_skin_development | 1.78611789 |
18 | MP0003122_maternal_imprinting | 1.74158628 |
19 | MP0010352_gastrointestinal_tract_polyps | 1.70905869 |
20 | MP0000534_abnormal_ureter_morphology | 1.70844941 |
21 | MP0006138_congestive_heart_failure | 1.68593117 |
22 | MP0010368_abnormal_lymphatic_system | 1.67658949 |
23 | MP0000537_abnormal_urethra_morphology | 1.65508471 |
24 | MP0002938_white_spotting | 1.64941746 |
25 | MP0001293_anophthalmia | 1.63691899 |
26 | MP0005330_cardiomyopathy | 1.63164904 |
27 | MP0005508_abnormal_skeleton_morphology | 1.60196407 |
28 | MP0001879_abnormal_lymphatic_vessel | 1.58854017 |
29 | MP0010030_abnormal_orbit_morphology | 1.57894898 |
30 | MP0003091_abnormal_cell_migration | 1.57652059 |
31 | MP0003942_abnormal_urinary_system | 1.56910172 |
32 | MP0002295_abnormal_pulmonary_circulatio | 1.55908345 |
33 | MP0005257_abnormal_intraocular_pressure | 1.55690905 |
34 | MP0004036_abnormal_muscle_relaxation | 1.54657668 |
35 | MP0002060_abnormal_skin_morphology | 1.54128098 |
36 | MP0001346_abnormal_lacrimal_gland | 1.52873284 |
37 | MP0000767_abnormal_smooth_muscle | 1.50967762 |
38 | MP0000778_abnormal_nervous_system | 1.47950604 |
39 | MP0008775_abnormal_heart_ventricle | 1.47271046 |
40 | MP0002837_dystrophic_cardiac_calcinosis | 1.45877089 |
41 | MP0000733_abnormal_muscle_development | 1.44133516 |
42 | MP0003136_yellow_coat_color | 1.44096491 |
43 | MP0002972_abnormal_cardiac_muscle | 1.42020509 |
44 | MP0010630_abnormal_cardiac_muscle | 1.41329398 |
45 | MP0006292_abnormal_olfactory_placode | 1.40744656 |
46 | MP0000750_abnormal_muscle_regeneration | 1.39820417 |
47 | MP0004087_abnormal_muscle_fiber | 1.39011880 |
48 | MP0010234_abnormal_vibrissa_follicle | 1.38214917 |
49 | MP0002108_abnormal_muscle_morphology | 1.38025946 |
50 | MP0000462_abnormal_digestive_system | 1.37525968 |
51 | MP0003828_pulmonary_edema | 1.37309244 |
52 | MP0004215_abnormal_myocardial_fiber | 1.36720821 |
53 | MP0003115_abnormal_respiratory_system | 1.36093844 |
54 | MP0009250_abnormal_appendicular_skeleto | 1.35238728 |
55 | MP0000049_abnormal_middle_ear | 1.32624018 |
56 | MP0005023_abnormal_wound_healing | 1.32519587 |
57 | MP0002697_abnormal_eye_size | 1.31901996 |
58 | MP0001286_abnormal_eye_development | 1.29787989 |
59 | MP0002282_abnormal_trachea_morphology | 1.26242389 |
60 | MP0003119_abnormal_digestive_system | 1.25221892 |
61 | MP0008789_abnormal_olfactory_epithelium | 1.24977091 |
62 | MP0002896_abnormal_bone_mineralization | 1.24366838 |
63 | MP0003890_abnormal_embryonic-extraembry | 1.24338714 |
64 | MP0003938_abnormal_ear_development | 1.23480640 |
65 | MP0001544_abnormal_cardiovascular_syste | 1.23325616 |
66 | MP0005385_cardiovascular_system_phenoty | 1.23325616 |
67 | MP0009053_abnormal_anal_canal | 1.22725312 |
68 | MP0005620_abnormal_muscle_contractility | 1.19836082 |
69 | MP0000428_abnormal_craniofacial_morphol | 1.14556427 |
70 | MP0002128_abnormal_blood_circulation | 1.13291722 |
71 | MP0003045_fibrosis | 1.12371515 |
72 | MP0002084_abnormal_developmental_patter | 1.12026009 |
73 | MP0001849_ear_inflammation | 1.11736938 |
74 | MP0000749_muscle_degeneration | 1.11624238 |
75 | MP0003567_abnormal_fetal_cardiomyocyte | 1.10159828 |
76 | MP0003283_abnormal_digestive_organ | 1.08607297 |
77 | MP0001177_atelectasis | 1.08536043 |
78 | MP0004858_abnormal_nervous_system | 1.07862436 |
79 | MP0004233_abnormal_muscle_weight | 1.05086800 |
80 | MP0002111_abnormal_tail_morphology | 1.05059808 |
81 | MP0005394_taste/olfaction_phenotype | 1.04383015 |
82 | MP0005499_abnormal_olfactory_system | 1.04383015 |
83 | MP0001299_abnormal_eye_distance/ | 1.04363404 |
84 | MP0002932_abnormal_joint_morphology | 1.01726653 |
85 | MP0000762_abnormal_tongue_morphology | 1.01623002 |
86 | MP0005409_darkened_coat_color | 1.01159459 |
87 | MP0003861_abnormal_nervous_system | 1.00884801 |
88 | MP0000383_abnormal_hair_follicle | 1.00438495 |
89 | MP0004130_abnormal_muscle_cell | 0.99834918 |
90 | MP0010678_abnormal_skin_adnexa | 0.98491404 |
91 | MP0005193_abnormal_anterior_eye | 0.97645827 |
92 | MP0002168_other_aberrant_phenotype | 0.97556207 |
93 | MP0002925_abnormal_cardiovascular_devel | 0.96867245 |
94 | MP0002234_abnormal_pharynx_morphology | 0.96774466 |
95 | MP0000013_abnormal_adipose_tissue | 0.96037757 |
96 | MP0009780_abnormal_chondrocyte_physiolo | 0.95807635 |
97 | MP0005197_abnormal_uvea_morphology | 0.95797113 |
98 | * MP0001614_abnormal_blood_vessel | 0.95541633 |
99 | MP0000163_abnormal_cartilage_morphology | 0.95388408 |
100 | MP0003300_gastrointestinal_ulcer | 0.95134166 |
101 | MP0002085_abnormal_embryonic_tissue | 0.94795792 |
102 | MP0002249_abnormal_larynx_morphology | 0.93258647 |
103 | MP0003315_abnormal_perineum_morphology | 0.92792771 |
104 | MP0002098_abnormal_vibrissa_morphology | 0.92397805 |
105 | MP0003935_abnormal_craniofacial_develop | 0.92387321 |
106 | MP0004484_altered_response_of | 0.91915309 |
107 | MP0002109_abnormal_limb_morphology | 0.90790936 |
108 | MP0005076_abnormal_cell_differentiation | 0.89838739 |
109 | MP0000467_abnormal_esophagus_morphology | 0.89706463 |
110 | MP0000266_abnormal_heart_morphology | 0.88373699 |
111 | MP0004133_heterotaxia | 0.86898893 |
112 | MP0009703_decreased_birth_body | 0.86599188 |
113 | MP0002233_abnormal_nose_morphology | 0.86388821 |
114 | MP0000003_abnormal_adipose_tissue | 0.85843318 |
115 | MP0003755_abnormal_palate_morphology | 0.84464957 |
116 | MP0002115_abnormal_skeleton_extremities | 0.84270629 |
117 | MP0005171_absent_coat_pigmentation | 0.83479588 |
118 | MP0002877_abnormal_melanocyte_morpholog | 0.83112537 |
119 | MP0002133_abnormal_respiratory_system | 0.82569542 |
120 | MP0005388_respiratory_system_phenotype | 0.82569542 |
121 | MP0000432_abnormal_head_morphology | 0.82525075 |
122 | MP0009672_abnormal_birth_weight | 0.82400621 |
123 | MP0001915_intracranial_hemorrhage | 0.81683769 |
124 | MP0003950_abnormal_plasma_membrane | 0.80775755 |
125 | MP0003937_abnormal_limbs/digits/tail_de | 0.79968300 |
126 | MP0003137_abnormal_impulse_conducting | 0.79157856 |
127 | MP0003984_embryonic_growth_retardation | 0.78108966 |
128 | MP0005369_muscle_phenotype | 0.77623050 |
129 | MP0000026_abnormal_inner_ear | 0.77615696 |
130 | MP0002088_abnormal_embryonic_growth/wei | 0.77413493 |
131 | MP0000516_abnormal_urinary_system | 0.77370988 |
132 | MP0005367_renal/urinary_system_phenotyp | 0.77370988 |
133 | MP0002092_abnormal_eye_morphology | 0.77076998 |
134 | MP0005248_abnormal_Harderian_gland | 0.76409602 |
135 | MP0005595_abnormal_vascular_smooth | 0.76340249 |
136 | MP0005391_vision/eye_phenotype | 0.76042156 |
137 | MP0002114_abnormal_axial_skeleton | 0.74478498 |
138 | MP0002089_abnormal_postnatal_growth/wei | 0.74270613 |
139 | MP0002116_abnormal_craniofacial_bone | 0.73431443 |
140 | MP0005380_embryogenesis_phenotype | 0.72923657 |
141 | MP0001672_abnormal_embryogenesis/_devel | 0.72923657 |
142 | MP0001340_abnormal_eyelid_morphology | 0.72562055 |
143 | MP0002081_perinatal_lethality | 0.69499686 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Protrusio acetabuli (HP:0003179) | 6.05844744 |
2 | Premature rupture of membranes (HP:0001788) | 5.98082165 |
3 | Ankle contracture (HP:0006466) | 4.87274262 |
4 | Shallow orbits (HP:0000586) | 4.46166251 |
5 | Broad metatarsal (HP:0001783) | 4.46122962 |
6 | Atrophic scars (HP:0001075) | 4.39447958 |
7 | Aortic dissection (HP:0002647) | 4.28112674 |
8 | Cerebral aneurysm (HP:0004944) | 4.12965645 |
9 | Bladder diverticulum (HP:0000015) | 3.80083645 |
10 | Aortic aneurysm (HP:0004942) | 3.78836614 |
11 | Soft skin (HP:0000977) | 3.56766778 |
12 | Follicular hyperkeratosis (HP:0007502) | 3.31376452 |
13 | Fragile skin (HP:0001030) | 3.27066354 |
14 | Right ventricular cardiomyopathy (HP:0011663) | 3.10415811 |
15 | Increased connective tissue (HP:0009025) | 3.09099960 |
16 | Type 1 muscle fiber predominance (HP:0003803) | 3.04556660 |
17 | Mitral valve prolapse (HP:0001634) | 2.96843839 |
18 | Neonatal short-limb short stature (HP:0008921) | 2.96274567 |
19 | Dilatation of the ascending aorta (HP:0005111) | 2.94821802 |
20 | Cutaneous finger syndactyly (HP:0010554) | 2.92687654 |
21 | Peritonitis (HP:0002586) | 2.89790071 |
22 | Vitreoretinal degeneration (HP:0000655) | 2.87639321 |
23 | Abnormality of dentin (HP:0010299) | 2.84614933 |
24 | Cervical subluxation (HP:0003308) | 2.78374775 |
25 | Muscle fiber splitting (HP:0003555) | 2.78242162 |
26 | Partial duplication of thumb phalanx (HP:0009944) | 2.76963094 |
27 | Spinal rigidity (HP:0003306) | 2.74128899 |
28 | Sudden death (HP:0001699) | 2.73807961 |
29 | Aneurysm (HP:0002617) | 2.69701880 |
30 | Mesangial abnormality (HP:0001966) | 2.69047381 |
31 | Hypoplasia of the iris (HP:0007676) | 2.67569359 |
32 | Buphthalmos (HP:0000557) | 2.67072250 |
33 | Cutaneous syndactyly (HP:0012725) | 2.63738872 |
34 | Vascular tortuosity (HP:0004948) | 2.57375976 |
35 | Wrist flexion contracture (HP:0001239) | 2.56270390 |
36 | Wormian bones (HP:0002645) | 2.55702580 |
37 | Partial duplication of the phalanx of hand (HP:0009999) | 2.54033512 |
38 | Hyporeflexia of lower limbs (HP:0002600) | 2.52900415 |
39 | Increased variability in muscle fiber diameter (HP:0003557) | 2.51026568 |
40 | Blue sclerae (HP:0000592) | 2.50544952 |
41 | Ventricular tachycardia (HP:0004756) | 2.46390570 |
42 | Overgrowth (HP:0001548) | 2.44923149 |
43 | Asymmetry of the thorax (HP:0001555) | 2.41589521 |
44 | Preaxial foot polydactyly (HP:0001841) | 2.41399495 |
45 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.38314480 |
46 | Abnormality of the ischium (HP:0003174) | 2.37122756 |
47 | Scapular winging (HP:0003691) | 2.35885198 |
48 | Hyperextensible skin (HP:0000974) | 2.35676130 |
49 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 2.35189568 |
50 | Genu recurvatum (HP:0002816) | 2.30290880 |
51 | Lipoatrophy (HP:0100578) | 2.30056875 |
52 | Bowel diverticulosis (HP:0005222) | 2.29875946 |
53 | Subacute progressive viral hepatitis (HP:0006572) | 2.26599700 |
54 | Lymphangioma (HP:0100764) | 2.26207716 |
55 | Midline defect of the nose (HP:0004122) | 2.24766026 |
56 | Arterial tortuosity (HP:0005116) | 2.22853255 |
57 | Pterygium (HP:0001059) | 2.19258280 |
58 | Broad thumb (HP:0011304) | 2.18039741 |
59 | Mitral regurgitation (HP:0001653) | 2.15129262 |
60 | Camptodactyly of toe (HP:0001836) | 2.13283574 |
61 | Thin bony cortex (HP:0002753) | 2.12644985 |
62 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.12240150 |
63 | Turricephaly (HP:0000262) | 2.11869917 |
64 | Trigonocephaly (HP:0000243) | 2.10617169 |
65 | Focal segmental glomerulosclerosis (HP:0000097) | 2.10316796 |
66 | Deviation of the hallux (HP:0010051) | 2.08934543 |
67 | Wide anterior fontanel (HP:0000260) | 2.08596486 |
68 | Abnormality of the calf musculature (HP:0001430) | 2.07847814 |
69 | Atrial fibrillation (HP:0005110) | 2.05721026 |
70 | Knee flexion contracture (HP:0006380) | 2.04540900 |
71 | Elbow flexion contracture (HP:0002987) | 2.04534638 |
72 | Short hallux (HP:0010109) | 2.03711951 |
73 | Coronal craniosynostosis (HP:0004440) | 2.03493998 |
74 | Missing ribs (HP:0000921) | 2.02579335 |
75 | Vertebral arch anomaly (HP:0008438) | 2.02100344 |
76 | Broad toe (HP:0001837) | 2.00444793 |
77 | Nuclear cataract (HP:0100018) | 1.99274064 |
78 | Broad ribs (HP:0000885) | 1.98423808 |
79 | Alacrima (HP:0000522) | 1.98356753 |
80 | Difficulty climbing stairs (HP:0003551) | 1.97836059 |
81 | Natal tooth (HP:0000695) | 1.97672506 |
82 | Osteolytic defects of the hand bones (HP:0009699) | 1.97242054 |
83 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 1.97242054 |
84 | Abnormality of the calcaneus (HP:0008364) | 1.97108685 |
85 | Supraventricular arrhythmia (HP:0005115) | 1.97016086 |
86 | Hallux valgus (HP:0001822) | 1.97009048 |
87 | Ectopia lentis (HP:0001083) | 1.96463643 |
88 | Broad finger (HP:0001500) | 1.96450153 |
89 | Bifid tongue (HP:0010297) | 1.95839499 |
90 | Broad palm (HP:0001169) | 1.94922099 |
91 | Fragile nails (HP:0001808) | 1.94889501 |
92 | Subaortic stenosis (HP:0001682) | 1.94465319 |
93 | Abnormality of the left ventricular outflow tract (HP:0011103) | 1.94465319 |
94 | Limited hip movement (HP:0008800) | 1.94315572 |
95 | Joint laxity (HP:0001388) | 1.94293639 |
96 | Infantile muscular hypotonia (HP:0008947) | 1.94160008 |
97 | Rectal prolapse (HP:0002035) | 1.94044848 |
98 | Broad phalanges of the hand (HP:0009768) | 1.93692936 |
99 | Abnormality of the lacrimal duct (HP:0011481) | 1.92824715 |
100 | Synostosis of carpal bones (HP:0005048) | 1.92751455 |
101 | Hip contracture (HP:0003273) | 1.91988805 |
102 | Primary atrial arrhythmia (HP:0001692) | 1.91375935 |
103 | Milia (HP:0001056) | 1.91308200 |
104 | Limited elbow extension (HP:0001377) | 1.91218144 |
105 | Biconcave vertebral bodies (HP:0004586) | 1.89387607 |
106 | Vertebral clefting (HP:0008428) | 1.89021764 |
107 | Tracheomalacia (HP:0002779) | 1.88933328 |
108 | High anterior hairline (HP:0009890) | 1.88361055 |
109 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.88085601 |
110 | Vertebral hypoplasia (HP:0008417) | 1.88085601 |
111 | Broad phalanx (HP:0006009) | 1.87735867 |
112 | Hepatoblastoma (HP:0002884) | 1.87679008 |
113 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.87125652 |
114 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.86717608 |
115 | Short 4th metacarpal (HP:0010044) | 1.86717608 |
116 | Myelomeningocele (HP:0002475) | 1.85326507 |
117 | Bronchomalacia (HP:0002780) | 1.85132451 |
118 | Mixed hearing impairment (HP:0000410) | 1.84677168 |
119 | Abnormality of cochlea (HP:0000375) | 1.83920042 |
120 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 1.83227621 |
121 | Thin ribs (HP:0000883) | 1.82923991 |
122 | Pulmonary artery stenosis (HP:0004415) | 1.82475345 |
123 | Short nail (HP:0001799) | 1.82212159 |
124 | Mesomelia (HP:0003027) | 1.81962408 |
125 | Aplasia involving bones of the upper limbs (HP:0009823) | 1.81534776 |
126 | Aplasia of the phalanges of the hand (HP:0009802) | 1.81534776 |
127 | Aplasia involving bones of the extremities (HP:0009825) | 1.81534776 |
128 | Hypoplastic labia majora (HP:0000059) | 1.81517422 |
129 | Hypoplastic ischia (HP:0003175) | 1.81495760 |
130 | Congenital glaucoma (HP:0001087) | 1.81012487 |
131 | Esophageal atresia (HP:0002032) | 1.80966280 |
132 | Decreased lacrimation (HP:0000633) | 1.80321079 |
133 | Abnormality of the anterior chamber (HP:0000593) | 1.80188088 |
134 | 11 pairs of ribs (HP:0000878) | 1.79571597 |
135 | Supraventricular tachycardia (HP:0004755) | 1.79229916 |
136 | Flat acetabular roof (HP:0003180) | 1.79196518 |
137 | Venous abnormality (HP:0002624) | 1.78938173 |
138 | Tibial bowing (HP:0002982) | 1.78641122 |
139 | Duplication of thumb phalanx (HP:0009942) | 1.77648153 |
140 | Abnormality of the nasolacrimal system (HP:0000614) | 1.77235675 |
141 | Long toe (HP:0010511) | 1.76717767 |
142 | Abnormality of the dental root (HP:0006486) | 1.76704424 |
143 | Taurodontia (HP:0000679) | 1.76704424 |
144 | Abnormality of permanent molar morphology (HP:0011071) | 1.76704424 |
145 | Renal duplication (HP:0000075) | 1.76290616 |
146 | Venous insufficiency (HP:0005293) | 1.75611414 |
147 | Broad hallux (HP:0010055) | 1.75258332 |
148 | Choanal stenosis (HP:0000452) | 1.74817813 |
149 | Abnormality of the 4th metacarpal (HP:0010012) | 1.74387497 |
150 | Omphalocele (HP:0001539) | 1.72664984 |
151 | Exostoses (HP:0100777) | 1.71924419 |
152 | Advanced eruption of teeth (HP:0006288) | 1.71070506 |
153 | Tarsal synostosis (HP:0008368) | 1.70979145 |
154 | Ulnar bowing (HP:0003031) | 1.70634361 |
155 | Broad long bones (HP:0005622) | 1.69888658 |
156 | Morphological abnormality of the middle ear (HP:0008609) | 1.69603557 |
157 | Abnormality of incisor morphology (HP:0011063) | 1.68936243 |
158 | Abnormality of molar (HP:0011077) | 1.67802881 |
159 | Abnormality of molar morphology (HP:0011070) | 1.67802881 |
160 | Anophthalmia (HP:0000528) | 1.64534645 |
161 | Abnormality of the pubic bones (HP:0003172) | 1.63489692 |
162 | Abnormality of the aortic arch (HP:0012303) | 1.63320551 |
163 | Renal hypoplasia (HP:0000089) | 1.62815133 |
164 | Split foot (HP:0001839) | 1.62752254 |
165 | Fibular hypoplasia (HP:0003038) | 1.60616695 |
166 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.58920701 |
167 | Abnormality of the labia majora (HP:0012881) | 1.58440952 |
168 | Hypoplastic pelvis (HP:0008839) | 1.57845567 |
169 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.56608975 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TTN | 4.63835097 |
2 | TRIB3 | 3.82655798 |
3 | PKN2 | 3.20733750 |
4 | DDR2 | 3.10114794 |
5 | EPHB2 | 2.97459399 |
6 | PDGFRA | 2.93396653 |
7 | PNCK | 2.70947810 |
8 | LATS1 | 2.66602130 |
9 | MYLK | 2.59204197 |
10 | EPHA4 | 2.37629812 |
11 | SIK1 | 2.31805524 |
12 | DMPK | 2.26869238 |
13 | PAK3 | 2.03496759 |
14 | RIPK1 | 2.03296856 |
15 | PAK2 | 2.01689496 |
16 | PTK6 | 1.93827610 |
17 | LMTK2 | 1.90117926 |
18 | FER | 1.88161716 |
19 | CAMK1G | 1.84970626 |
20 | CASK | 1.74442473 |
21 | PIK3CA | 1.69111722 |
22 | LATS2 | 1.66364198 |
23 | LRRK2 | 1.59381618 |
24 | ROCK1 | 1.57263474 |
25 | TGFBR2 | 1.56070248 |
26 | EPHA3 | 1.55948224 |
27 | TRPM7 | 1.55916851 |
28 | CAMK1D | 1.53144237 |
29 | PTK2 | 1.53025970 |
30 | PAK4 | 1.52800886 |
31 | TYRO3 | 1.50333558 |
32 | EPHA2 | 1.49625968 |
33 | MKNK1 | 1.46179795 |
34 | BMX | 1.32932684 |
35 | MAPK15 | 1.30814025 |
36 | WNK4 | 1.26845095 |
37 | BRD4 | 1.23044672 |
38 | CDK12 | 1.21802605 |
39 | STK38L | 1.20066191 |
40 | PDGFRB | 1.15028738 |
41 | ILK | 1.13633498 |
42 | ERN1 | 1.10946222 |
43 | MET | 1.10865156 |
44 | TIE1 | 1.09784586 |
45 | AKT3 | 1.09297446 |
46 | ROCK2 | 1.08075725 |
47 | WEE1 | 1.07032265 |
48 | FGFR1 | 1.06088702 |
49 | PBK | 1.01325899 |
50 | BCR | 0.97693146 |
51 | NTRK2 | 0.96961836 |
52 | EPHB1 | 0.95970388 |
53 | MTOR | 0.95738305 |
54 | STK3 | 0.92591405 |
55 | PRKD1 | 0.91980376 |
56 | PTK2B | 0.91276553 |
57 | FRK | 0.89651661 |
58 | MKNK2 | 0.87551934 |
59 | EEF2K | 0.85459901 |
60 | TESK1 | 0.85348569 |
61 | BRSK2 | 0.82851636 |
62 | CDC42BPA | 0.82290154 |
63 | STK10 | 0.81888793 |
64 | PDK3 | 0.81543813 |
65 | PDK4 | 0.81543813 |
66 | PHKG2 | 0.80955404 |
67 | PHKG1 | 0.80955404 |
68 | LIMK1 | 0.79723164 |
69 | FGFR2 | 0.78774284 |
70 | KSR1 | 0.77246284 |
71 | ERBB3 | 0.76290780 |
72 | NEK1 | 0.72881156 |
73 | MARK1 | 0.71865715 |
74 | OBSCN | 0.70251000 |
75 | DAPK3 | 0.70126789 |
76 | TTK | 0.70024032 |
77 | PDK2 | 0.69825738 |
78 | RET | 0.68484864 |
79 | TNIK | 0.64006047 |
80 | MAP2K1 | 0.63431207 |
81 | DYRK1B | 0.62129754 |
82 | WNK1 | 0.61706304 |
83 | NEK9 | 0.60626191 |
84 | MAPKAPK5 | 0.60316618 |
85 | MAP3K10 | 0.60163435 |
86 | SGK494 | 0.60132681 |
87 | SGK223 | 0.60132681 |
88 | NTRK1 | 0.60042442 |
89 | TSSK6 | 0.57343471 |
90 | STK39 | 0.57211205 |
91 | ERBB2 | 0.55978311 |
92 | MAP3K3 | 0.55847763 |
93 | RPS6KA2 | 0.55385252 |
94 | ZAK | 0.53443543 |
95 | PLK2 | 0.52810822 |
96 | MST1R | 0.50694751 |
97 | INSR | 0.49835628 |
98 | NEK2 | 0.49495270 |
99 | PRKCE | 0.49273234 |
100 | CDK6 | 0.49247108 |
101 | STK38 | 0.48211796 |
102 | PLK4 | 0.48207820 |
103 | ICK | 0.47555520 |
104 | SGK2 | 0.47319407 |
105 | MAP3K7 | 0.47176408 |
106 | PRKCH | 0.46950790 |
107 | SRC | 0.46336920 |
108 | FGFR3 | 0.46255172 |
109 | GSK3A | 0.45208565 |
110 | FLT3 | 0.44070831 |
111 | CDK3 | 0.43637777 |
112 | MAP3K2 | 0.43633340 |
113 | BRSK1 | 0.42525734 |
114 | MAP3K4 | 0.41525907 |
115 | SRPK1 | 0.40478528 |
116 | NEK6 | 0.40372733 |
117 | ERBB4 | 0.40314147 |
118 | STK24 | 0.40193363 |
119 | NTRK3 | 0.39968326 |
120 | MELK | 0.39438406 |
121 | PRKD2 | 0.38346011 |
122 | NUAK1 | 0.37963622 |
123 | RPS6KL1 | 0.37793500 |
124 | RPS6KC1 | 0.37793500 |
125 | PRKAA2 | 0.37491244 |
126 | FGFR4 | 0.36386290 |
127 | SGK3 | 0.36356549 |
128 | MARK2 | 0.36159811 |
129 | MAPK10 | 0.35998185 |
130 | TGFBR1 | 0.35975513 |
131 | RPS6KB2 | 0.35963176 |
132 | RPS6KB1 | 0.34801859 |
133 | MOS | 0.34586398 |
134 | IGF1R | 0.34319272 |
135 | SCYL2 | 0.33786867 |
136 | MAP2K2 | 0.33776458 |
137 | CAMK2D | 0.33586979 |
138 | PAK6 | 0.33316746 |
139 | PRKD3 | 0.33202065 |
140 | UHMK1 | 0.32176210 |
141 | ADRBK1 | 0.32114627 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * ECM-receptor interaction_Homo sapiens_hsa04512 | 4.08969874 |
2 | * Focal adhesion_Homo sapiens_hsa04510 | 3.06958221 |
3 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.86001040 |
4 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 2.85894214 |
5 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.76589820 |
6 | Adherens junction_Homo sapiens_hsa04520 | 2.48664205 |
7 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 2.38516847 |
8 | * Protein digestion and absorption_Homo sapiens_hsa04974 | 2.19147602 |
9 | * Amoebiasis_Homo sapiens_hsa05146 | 2.18953887 |
10 | * Small cell lung cancer_Homo sapiens_hsa05222 | 2.14738213 |
11 | Hippo signaling pathway_Homo sapiens_hsa04390 | 2.10406172 |
12 | Basal cell carcinoma_Homo sapiens_hsa05217 | 2.02825193 |
13 | * AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.95733598 |
14 | Bladder cancer_Homo sapiens_hsa05219 | 1.91506874 |
15 | Tight junction_Homo sapiens_hsa04530 | 1.81203962 |
16 | Viral myocarditis_Homo sapiens_hsa05416 | 1.74258085 |
17 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.71365950 |
18 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.67825378 |
19 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.67821126 |
20 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.56819490 |
21 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.48937926 |
22 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.40918639 |
23 | * PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.33480261 |
24 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.32496195 |
25 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.32189082 |
26 | Axon guidance_Homo sapiens_hsa04360 | 1.24714558 |
27 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.23833009 |
28 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.18026442 |
29 | Melanoma_Homo sapiens_hsa05218 | 1.16726896 |
30 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.16064780 |
31 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.15343613 |
32 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.13438607 |
33 | * Pathways in cancer_Homo sapiens_hsa05200 | 1.09037053 |
34 | Melanogenesis_Homo sapiens_hsa04916 | 1.04951204 |
35 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.03794272 |
36 | Prostate cancer_Homo sapiens_hsa05215 | 1.03755631 |
37 | Endometrial cancer_Homo sapiens_hsa05213 | 1.02963939 |
38 | Glioma_Homo sapiens_hsa05214 | 1.02535444 |
39 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.01158208 |
40 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.00402822 |
41 | Malaria_Homo sapiens_hsa05144 | 0.99544108 |
42 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.96796007 |
43 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.96278952 |
44 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.96052757 |
45 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.94594137 |
46 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.94279373 |
47 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.91864788 |
48 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.90432114 |
49 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.88014265 |
50 | Platelet activation_Homo sapiens_hsa04611 | 0.87877676 |
51 | Insulin resistance_Homo sapiens_hsa04931 | 0.84027950 |
52 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.83821625 |
53 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.82982250 |
54 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.82969271 |
55 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.81619375 |
56 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.81416397 |
57 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.80263960 |
58 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.78538023 |
59 | HTLV-I infection_Homo sapiens_hsa05166 | 0.77265231 |
60 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.76589816 |
61 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.75978218 |
62 | Lysine degradation_Homo sapiens_hsa00310 | 0.75640649 |
63 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.70804992 |
64 | Prion diseases_Homo sapiens_hsa05020 | 0.70584015 |
65 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.70150779 |
66 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.68852796 |
67 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.68132429 |
68 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.68017802 |
69 | Gap junction_Homo sapiens_hsa04540 | 0.67353034 |
70 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.67308801 |
71 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.66680039 |
72 | Cell cycle_Homo sapiens_hsa04110 | 0.65153988 |
73 | Colorectal cancer_Homo sapiens_hsa05210 | 0.65130975 |
74 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.64182087 |
75 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.64005808 |
76 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.62868293 |
77 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.62766504 |
78 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.60962698 |
79 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.60832749 |
80 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.60263647 |
81 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.59619919 |
82 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.59488627 |
83 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.58981363 |
84 | Renin secretion_Homo sapiens_hsa04924 | 0.58806986 |
85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.58176989 |
86 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.57669137 |
87 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.55969829 |
88 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.55895169 |
89 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.55539438 |
90 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.55502871 |
91 | Bile secretion_Homo sapiens_hsa04976 | 0.55149538 |
92 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.55137950 |
93 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.55132048 |
94 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.54473480 |
95 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.54358008 |
96 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.53193034 |
97 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.52513535 |
98 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.51788552 |
99 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.51416140 |
100 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.51092511 |
101 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.49817191 |
102 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.49314234 |
103 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.48801911 |
104 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.48636259 |
105 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.48256679 |
106 | Thyroid cancer_Homo sapiens_hsa05216 | 0.47899679 |
107 | Circadian rhythm_Homo sapiens_hsa04710 | 0.46714035 |
108 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.46495035 |
109 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.46315498 |
110 | Cocaine addiction_Homo sapiens_hsa05030 | 0.45780248 |
111 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.45570365 |
112 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.45247056 |
113 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.44423743 |
114 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.43909213 |
115 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.43847241 |
116 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.43587746 |
117 | Endocytosis_Homo sapiens_hsa04144 | 0.42706925 |
118 | TNF signaling pathway_Homo sapiens_hsa04668 | 0.42466624 |
119 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.41315462 |
120 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.41002451 |
121 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.40617631 |
122 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.40230113 |
123 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.39975054 |
124 | Mineral absorption_Homo sapiens_hsa04978 | 0.38575056 |
125 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.36535980 |
126 | ABC transporters_Homo sapiens_hsa02010 | 0.34320293 |
127 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.34067604 |
128 | Histidine metabolism_Homo sapiens_hsa00340 | 0.33900509 |
129 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.32047678 |