COLGALT2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1postsynaptic membrane organization (GO:0001941)7.19711350
2presynaptic membrane assembly (GO:0097105)5.97238985
3cellular potassium ion homeostasis (GO:0030007)5.73179657
4presynaptic membrane organization (GO:0097090)5.69025021
5L-amino acid import (GO:0043092)5.19126326
6sodium ion export (GO:0071436)5.11753381
7membrane depolarization during cardiac muscle cell action potential (GO:0086012)5.10854720
8neuron cell-cell adhesion (GO:0007158)4.88094363
9synaptic vesicle maturation (GO:0016188)4.76380871
10amino acid import (GO:0043090)4.73496910
11potassium ion homeostasis (GO:0055075)4.62909165
12glomerular visceral epithelial cell development (GO:0072015)4.37901225
13regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.33545911
14neuronal action potential propagation (GO:0019227)4.27757802
15auditory behavior (GO:0031223)4.27040100
16locomotory exploration behavior (GO:0035641)4.27009904
17neuronal ion channel clustering (GO:0045161)4.25825679
18neurotransmitter uptake (GO:0001504)4.24871572
19synaptic vesicle docking involved in exocytosis (GO:0016081)4.18712706
20mechanosensory behavior (GO:0007638)4.14459337
21regulation of synaptic vesicle exocytosis (GO:2000300)4.13530640
22vocalization behavior (GO:0071625)4.13073887
23positive regulation of excitatory postsynaptic membrane potential (GO:2000463)4.03725981
24cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.02716975
25neurotransmitter-gated ion channel clustering (GO:0072578)3.99334950
26ionotropic glutamate receptor signaling pathway (GO:0035235)3.98007665
27glomerular epithelial cell development (GO:0072310)3.96093201
28protein localization to synapse (GO:0035418)3.94722710
29cell aggregation (GO:0098743)3.91565265
30cartilage condensation (GO:0001502)3.91565265
31regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.91127303
32endocardial cushion morphogenesis (GO:0003203)3.88709016
33astrocyte differentiation (GO:0048708)3.76204211
34glomerular basement membrane development (GO:0032836)3.75481331
35regulation of short-term neuronal synaptic plasticity (GO:0048172)3.70018517
36positive regulation of potassium ion transmembrane transporter activity (GO:1901018)3.67423369
37glutamate secretion (GO:0014047)3.65945208
38synaptic vesicle exocytosis (GO:0016079)3.63538593
39acidic amino acid transport (GO:0015800)3.61640354
40regulation of synaptic vesicle transport (GO:1902803)3.60716765
41cell communication by electrical coupling (GO:0010644)3.54155958
42positive regulation of synaptic transmission, glutamatergic (GO:0051968)3.52663888
43regulation of somitogenesis (GO:0014807)3.51687337
44regulation of glutamate receptor signaling pathway (GO:1900449)3.50447863
45regulation of cardiac muscle cell contraction (GO:0086004)3.49767593
46glomerulus development (GO:0032835)3.45841635
47neuron recognition (GO:0008038)3.45690888
48synaptic transmission, glutamatergic (GO:0035249)3.43219411
49exploration behavior (GO:0035640)3.41963474
50regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.39270932
51regulation of synapse structural plasticity (GO:0051823)3.35164220
52L-glutamate transport (GO:0015813)3.32322489
53regulation of neuronal synaptic plasticity (GO:0048168)3.27448067
54response to auditory stimulus (GO:0010996)3.26202407
55cerebellar Purkinje cell layer development (GO:0021680)3.23257912
56axonal fasciculation (GO:0007413)3.23253350
57lymph vessel development (GO:0001945)3.22465219
58glutamate receptor signaling pathway (GO:0007215)3.21243164
59auditory receptor cell differentiation (GO:0042491)3.19418235
60cerebellar granule cell differentiation (GO:0021707)3.18588771
61membrane assembly (GO:0071709)3.17021917
62regulation of cell communication by electrical coupling (GO:0010649)3.15393129
63regulation of respiratory system process (GO:0044065)3.13869137
64chondrocyte development (GO:0002063)3.09869059
65regulation of synaptic transmission, glutamatergic (GO:0051966)3.08808160
66myelination (GO:0042552)3.08148561
67establishment of mitochondrion localization (GO:0051654)3.06026734
68positive regulation of dendritic spine development (GO:0060999)3.05274161
69astrocyte development (GO:0014002)3.03049323
70regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO3.01486045
71axon ensheathment in central nervous system (GO:0032291)3.01131450
72central nervous system myelination (GO:0022010)3.01131450
73dendrite morphogenesis (GO:0048813)3.00860047
74positive regulation of inositol phosphate biosynthetic process (GO:0060732)3.00553854
75negative regulation of synaptic transmission, GABAergic (GO:0032229)2.99480522
76negative regulation of homotypic cell-cell adhesion (GO:0034111)2.99268290
77negative regulation of synaptic transmission, glutamatergic (GO:0051967)2.98911923
78photoreceptor cell differentiation (GO:0046530)2.98271090
79eye photoreceptor cell differentiation (GO:0001754)2.98271090
80regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)2.98208704
81regulation of actin filament-based movement (GO:1903115)2.98061839
82cartilage development involved in endochondral bone morphogenesis (GO:0060351)2.97677671
83ensheathment of neurons (GO:0007272)2.97632385
84axon ensheathment (GO:0008366)2.97632385
85positive regulation of synapse maturation (GO:0090129)2.97325564
86vascular endothelial growth factor signaling pathway (GO:0038084)2.95928768
87regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)2.93123302
88regulation of voltage-gated calcium channel activity (GO:1901385)2.92532484
89transmission of nerve impulse (GO:0019226)2.92446348
90neuromuscular process controlling balance (GO:0050885)2.91075488
91positive regulation of potassium ion transmembrane transport (GO:1901381)2.90954968
92neurotransmitter secretion (GO:0007269)2.87839336
93neuron-neuron synaptic transmission (GO:0007270)2.87687324
94membrane depolarization during action potential (GO:0086010)2.87130431
95negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.85503512
96cerebral cortex radially oriented cell migration (GO:0021799)2.85420950
97synapse assembly (GO:0007416)2.84433995
98suckling behavior (GO:0001967)2.83563144
99mesenchyme morphogenesis (GO:0072132)2.82827075
100endothelial cell morphogenesis (GO:0001886)2.82475741
101regulation of relaxation of muscle (GO:1901077)2.81991353
102negative regulation of cytosolic calcium ion concentration (GO:0051481)2.81926420
103peptidyl-tyrosine autophosphorylation (GO:0038083)2.81337202
104regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.80711873
105endothelium development (GO:0003158)2.75751162
106negative regulation of platelet activation (GO:0010544)2.75653292
107regulation of long-term neuronal synaptic plasticity (GO:0048169)2.74872867
108positive regulation of calcium ion-dependent exocytosis (GO:0045956)2.74622708
109pyrimidine nucleobase catabolic process (GO:0006208)2.73323173
110chondroitin sulfate catabolic process (GO:0030207)2.71274091
111negative regulation of neurotransmitter transport (GO:0051589)2.69681800
112regulation of dendritic spine morphogenesis (GO:0061001)2.69601453
113oligodendrocyte differentiation (GO:0048709)2.69445758
114retinal ganglion cell axon guidance (GO:0031290)2.69160185
115cell communication involved in cardiac conduction (GO:0086065)2.67694896
116regulation of beta-amyloid formation (GO:1902003)2.66710708
117endothelial cell differentiation (GO:0045446)2.64813938
118neurotransmitter transport (GO:0006836)2.64787588
119limb bud formation (GO:0060174)2.64771415
120lateral sprouting from an epithelium (GO:0060601)2.59529251
121negative regulation of catenin import into nucleus (GO:0035414)2.56897443
122coronary vasculature morphogenesis (GO:0060977)2.56065976
123negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.53763890
124heart valve formation (GO:0003188)2.50408169
125retina vasculature morphogenesis in camera-type eye (GO:0061299)2.50403892
126detection of temperature stimulus (GO:0016048)2.50214239
127type B pancreatic cell proliferation (GO:0044342)2.49450270
128regulation of axon extension involved in axon guidance (GO:0048841)2.44930864
129collagen fibril organization (GO:0030199)2.44459719
130regulation of axon guidance (GO:1902667)2.42194502
131cellular response to vascular endothelial growth factor stimulus (GO:0035924)2.41625975
132cellular sodium ion homeostasis (GO:0006883)2.40164370
133positive regulation of alcohol biosynthetic process (GO:1902932)2.38003106
134Notch signaling involved in heart development (GO:0061314)2.37661744
135negative regulation of Rho protein signal transduction (GO:0035024)2.35632491
136cell migration involved in sprouting angiogenesis (GO:0002042)2.35327047
137negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067)2.33455769
138peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.32999897
139innervation (GO:0060384)2.32226250
140notochord development (GO:0030903)2.31645436
141blood vessel maturation (GO:0001955)2.28936463
142enteric nervous system development (GO:0048484)2.28403378
143cardiac muscle cell proliferation (GO:0060038)2.27752235
144dermatan sulfate biosynthetic process (GO:0030208)2.23966676
145regulation of extracellular matrix disassembly (GO:0010715)2.22873744
146heart valve morphogenesis (GO:0003179)2.22460632
147mechanoreceptor differentiation (GO:0042490)2.21108312
148sensory perception of sound (GO:0007605)2.20978316
149collagen catabolic process (GO:0030574)2.20776274
150vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.20723210
151sensory perception of mechanical stimulus (GO:0050954)2.19924641
152neuron remodeling (GO:0016322)2.19521266
153negative regulation of astrocyte differentiation (GO:0048712)2.19275718
154inner ear receptor cell differentiation (GO:0060113)2.18875558
155negative regulation of axon guidance (GO:1902668)2.17804980
156regulation of steroid hormone biosynthetic process (GO:0090030)2.17218845
157negative regulation of axon extension involved in axon guidance (GO:0048843)2.16945690
158positive regulation of focal adhesion assembly (GO:0051894)2.16652077
159positive regulation of cell junction assembly (GO:1901890)2.16652077
160collagen metabolic process (GO:0032963)2.16231998
161regulation of plasminogen activation (GO:0010755)2.15714956
162positive regulation of axon extension (GO:0045773)2.15213573
163detection of temperature stimulus involved in sensory perception of pain (GO:0050965)2.15112252
164detection of temperature stimulus involved in sensory perception (GO:0050961)2.15112252
165positive regulation of protein kinase C signaling (GO:0090037)2.15010450
166multicellular organismal macromolecule metabolic process (GO:0044259)2.14451963
167cellular response to sterol (GO:0036315)2.13687806
168heart trabecula formation (GO:0060347)2.13243220
169gap junction assembly (GO:0016264)2.12909438
170myelination in peripheral nervous system (GO:0022011)2.12839478
171peripheral nervous system axon ensheathment (GO:0032292)2.12839478
172keratan sulfate catabolic process (GO:0042340)2.11826604
173multicellular organismal catabolic process (GO:0044243)2.11784153
174regulation of endothelial cell differentiation (GO:0045601)2.10947662
175chondrocyte differentiation (GO:0002062)2.10560913
176C4-dicarboxylate transport (GO:0015740)2.09625970
177dermatan sulfate metabolic process (GO:0030205)2.09560617
178potassium ion import (GO:0010107)2.09472720
179dopamine biosynthetic process (GO:0042416)2.09262655
180cellular response to cholesterol (GO:0071397)2.08493211
181glycoprotein catabolic process (GO:0006516)2.07362045
182renal filtration (GO:0097205)2.05652207
183fatty acid elongation (GO:0030497)2.05351316
184regulation of skeletal muscle cell differentiation (GO:2001014)2.05098247
185regulation of inositol phosphate biosynthetic process (GO:0010919)2.04797074
186regulation of alkaline phosphatase activity (GO:0010692)2.04728528
187glomerular filtration (GO:0003094)2.04169235
188neuron maturation (GO:0042551)2.03533389
189regulation of vasculogenesis (GO:2001212)2.03334638
190alanine transport (GO:0032328)2.02991681
191positive regulation of adherens junction organization (GO:1903393)2.02797052
192multicellular organismal metabolic process (GO:0044236)2.02647365

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human3.93537164
2NR4A2_19515692_ChIP-ChIP_MN9D_Mouse3.29785869
3CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons3.20061691
4SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.56144318
5REST_21632747_ChIP-Seq_MESCs_Mouse2.49734512
6SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.40173716
7SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.38535352
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.35267233
9RNF2_18974828_ChIP-Seq_MESCs_Mouse2.35267233
10EED_16625203_ChIP-ChIP_MESCs_Mouse2.34594020
11JARID2_20064375_ChIP-Seq_MESCs_Mouse2.30527473
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.29982826
13EZH2_22144423_ChIP-Seq_EOC_Human2.28971051
14AR_21572438_ChIP-Seq_LNCaP_Human2.20738882
15SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.18125224
16RARB_27405468_Chip-Seq_BRAIN_Mouse2.14485723
17REST_18959480_ChIP-ChIP_MESCs_Mouse2.14446460
18MTF2_20144788_ChIP-Seq_MESCs_Mouse2.11092101
19JARID2_20075857_ChIP-Seq_MESCs_Mouse2.06620640
20EZH2_27304074_Chip-Seq_ESCs_Mouse1.99833955
21CDX2_19796622_ChIP-Seq_MESCs_Mouse1.98793957
22SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.92597417
23GBX2_23144817_ChIP-Seq_PC3_Human1.91063239
24EP300_21415370_ChIP-Seq_HL-1_Mouse1.90512807
25EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.88363324
26RNF2_27304074_Chip-Seq_ESCs_Mouse1.80928927
27ESR2_21235772_ChIP-Seq_MCF-7_Human1.80456920
28ZNF217_24962896_ChIP-Seq_MCF-7_Human1.78496529
29EZH2_27294783_Chip-Seq_ESCs_Mouse1.76219840
30SUZ12_27294783_Chip-Seq_ESCs_Mouse1.76209413
31ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.74088290
32PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.73306956
33WT1_19549856_ChIP-ChIP_CCG9911_Human1.66804759
34TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.63988311
35SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.59381687
36PIAS1_25552417_ChIP-Seq_VCAP_Human1.54730904
37RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.48534728
38SMAD_19615063_ChIP-ChIP_OVARY_Human1.47213479
39ESR1_20079471_ChIP-ChIP_T-47D_Human1.44314189
40CLOCK_20551151_ChIP-Seq_293T_Human1.44304678
41RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.43202371
42AHR_22903824_ChIP-Seq_MCF-7_Human1.41979481
43SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.41679964
44TP63_17297297_ChIP-ChIP_HaCaT_Human1.39013964
45NR3C1_23031785_ChIP-Seq_PC12_Mouse1.37980740
46PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.37583958
47OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.34700302
48CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.34318750
49OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.33245797
50ERG_21242973_ChIP-ChIP_JURKAT_Human1.32079758
51WT1_25993318_ChIP-Seq_PODOCYTE_Human1.31159464
52ARNT_22903824_ChIP-Seq_MCF-7_Human1.29941703
53HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.29761236
54RNF2_27304074_Chip-Seq_NSC_Mouse1.28607264
55ESR1_21235772_ChIP-Seq_MCF-7_Human1.26792706
56SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.25407624
57RING1B_27294783_Chip-Seq_ESCs_Mouse1.25229521
58SOX9_26525672_Chip-Seq_HEART_Mouse1.24643272
59TP53_18474530_ChIP-ChIP_U2OS_Human1.23545678
60ZFP281_18757296_ChIP-ChIP_E14_Mouse1.20800757
61SMAD3_21741376_ChIP-Seq_EPCs_Human1.20502849
62CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19638099
63PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.19166928
64TAF15_26573619_Chip-Seq_HEK293_Human1.18471569
65SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.18299654
66CJUN_26792858_Chip-Seq_BT549_Human1.18189729
67AR_19668381_ChIP-Seq_PC3_Human1.18124062
68SMAD4_21799915_ChIP-Seq_A2780_Human1.17999524
69AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.17757963
70RCOR3_21632747_ChIP-Seq_MESCs_Mouse1.17698510
71NRF2_20460467_ChIP-Seq_MEFs_Mouse1.17476013
72NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.17476013
73RBPJ_22232070_ChIP-Seq_NCS_Mouse1.16867121
74E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.14466767
75EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.14363796
76P300_19829295_ChIP-Seq_ESCs_Human1.14325149
77CBX2_27304074_Chip-Seq_ESCs_Mouse1.13649558
78WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.13566226
79NR3C1_21868756_ChIP-Seq_MCF10A_Human1.12861153
80SMAD3_21741376_ChIP-Seq_ESCs_Human1.10588582
81BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.10499655
82PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.10337760
83DROSHA_22980978_ChIP-Seq_HELA_Human1.09144480
84TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.08875702
85CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.08823386
86SOX2_21211035_ChIP-Seq_LN229_Gbm1.08793202
87BCAT_22108803_ChIP-Seq_LS180_Human1.08156468
88CTBP1_25329375_ChIP-Seq_LNCAP_Human1.07814945
89RING1B_27294783_Chip-Seq_NPCs_Mouse1.06854314
90TOP2B_26459242_ChIP-Seq_MCF-7_Human1.06329299
91CTBP2_25329375_ChIP-Seq_LNCAP_Human1.06258096
92CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse1.04869925
93TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.04582187
94KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.04032752
95CTNNB1_20460455_ChIP-Seq_HCT116_Human1.03302960
96DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03129443
97TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.03120080
98GATA1_26923725_Chip-Seq_HPCs_Mouse1.02398968
99RARG_19884340_ChIP-ChIP_MEFs_Mouse1.02196398
100MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.99517616
101ZFP57_27257070_Chip-Seq_ESCs_Mouse0.99209986
102TP53_20018659_ChIP-ChIP_R1E_Mouse0.98813785
103TCF4_23295773_ChIP-Seq_U87_Human0.98669758
104TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98452889
105POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.98452889
106GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.98426204
107UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.96388833
108P53_22127205_ChIP-Seq_FIBROBLAST_Human0.96336559
109RXR_22108803_ChIP-Seq_LS180_Human0.95518243
110FOXO3_23340844_ChIP-Seq_DLD1_Human0.95472036
111GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.94470800
112TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.94150313
113SMAD4_21741376_ChIP-Seq_HESCs_Human0.94062858
114ISL1_27105846_Chip-Seq_CPCs_Mouse0.93720044
115TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.93204416
116AR_25329375_ChIP-Seq_VCAP_Human0.93019980
117TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.92953942
118STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse0.91391362
119TCF4_18268006_ChIP-ChIP_LS174T_Human0.91173566
120SMAD3_21741376_ChIP-Seq_HESCs_Human0.91101783
121MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human0.90171904
122STAT3_23295773_ChIP-Seq_U87_Human0.90102177
123ZFP322A_24550733_ChIP-Seq_MESCs_Mouse0.90011095
124THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.89911866
125KDM2B_26808549_Chip-Seq_K562_Human0.89775743
126EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human0.89547210
127FOXM1_26456572_ChIP-Seq_MCF-7_Human0.89368997
128JUN_21703547_ChIP-Seq_K562_Human0.89224742
129MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.87190556
130SOX2_20726797_ChIP-Seq_SW620_Human0.87021868
131TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.86665333
132TCF3_18467660_ChIP-ChIP_MESCs_Mouse0.85267278
133LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.84387877
134YAP1_20516196_ChIP-Seq_MESCs_Mouse0.84093481

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern4.71664826
2MP0005423_abnormal_somatic_nervous4.22817061
3MP0003879_abnormal_hair_cell3.05363106
4MP0004272_abnormal_basement_membrane2.69990170
5MP0001984_abnormal_olfaction2.56322753
6MP0003878_abnormal_ear_physiology2.51795054
7MP0005377_hearing/vestibular/ear_phenot2.51795054
8MP0001485_abnormal_pinna_reflex2.51713330
9MP0009780_abnormal_chondrocyte_physiolo2.46434960
10MP0002063_abnormal_learning/memory/cond2.42593203
11MP0004134_abnormal_chest_morphology2.39229525
12MP0010368_abnormal_lymphatic_system2.38462654
13MP0001963_abnormal_hearing_physiology2.36803856
14MP0002735_abnormal_chemical_nociception2.34020726
15MP0004858_abnormal_nervous_system2.32323046
16MP0009745_abnormal_behavioral_response2.28635321
17MP0000026_abnormal_inner_ear2.14573716
18MP0001879_abnormal_lymphatic_vessel2.10374333
19MP0002282_abnormal_trachea_morphology2.09845739
20MP0005623_abnormal_meninges_morphology2.07061234
21MP0005503_abnormal_tendon_morphology2.01503094
22MP0009250_abnormal_appendicular_skeleto2.01011286
23MP0004084_abnormal_cardiac_muscle2.00245553
24MP0002572_abnormal_emotion/affect_behav1.98266063
25MP0002653_abnormal_ependyma_morphology1.96155815
26MP0003136_yellow_coat_color1.95741697
27MP0000751_myopathy1.91908550
28MP0000955_abnormal_spinal_cord1.82336404
29MP0004036_abnormal_muscle_relaxation1.81811085
30MP0008569_lethality_at_weaning1.79104112
31MP0009046_muscle_twitch1.76779420
32MP0005167_abnormal_blood-brain_barrier1.74605754
33MP0000163_abnormal_cartilage_morphology1.70248214
34MP0004885_abnormal_endolymph1.70129465
35MP0001529_abnormal_vocalization1.64728149
36MP0003646_muscle_fatigue1.58324053
37MP0001486_abnormal_startle_reflex1.56842280
38MP0003122_maternal_imprinting1.52653977
39MP0002557_abnormal_social/conspecific_i1.52530071
40MP0001270_distended_abdomen1.52241029
41MP0002882_abnormal_neuron_morphology1.51770515
42MP0003633_abnormal_nervous_system1.50503767
43MP0005508_abnormal_skeleton_morphology1.50424293
44MP0003942_abnormal_urinary_system1.49907636
45MP0009384_cardiac_valve_regurgitation1.48220128
46MP0004270_analgesia1.47771617
47MP0001299_abnormal_eye_distance/1.45671835
48MP0003123_paternal_imprinting1.43162923
49MP0002115_abnormal_skeleton_extremities1.40963599
50MP0004811_abnormal_neuron_physiology1.40579965
51MP0000534_abnormal_ureter_morphology1.40263140
52MP0003329_amyloid_beta_deposits1.40106387
53MP0002933_joint_inflammation1.38352803
54MP0001968_abnormal_touch/_nociception1.35304745
55MP0000762_abnormal_tongue_morphology1.34944222
56MP0005551_abnormal_eye_electrophysiolog1.32240473
57MP0002089_abnormal_postnatal_growth/wei1.31637071
58MP0000579_abnormal_nail_morphology1.30340120
59MP0002896_abnormal_bone_mineralization1.30268361
60MP0002152_abnormal_brain_morphology1.29270016
61MP0002066_abnormal_motor_capabilities/c1.28989925
62MP0004484_altered_response_of1.26559383
63MP0002638_abnormal_pupillary_reflex1.25766438
64MP0003631_nervous_system_phenotype1.25679056
65MP0001501_abnormal_sleep_pattern1.22876628
66MP0003632_abnormal_nervous_system1.22535148
67MP0003941_abnormal_skin_development1.22520252
68MP0002822_catalepsy1.22339084
69MP0002972_abnormal_cardiac_muscle1.22030390
70MP0000778_abnormal_nervous_system1.19097299
71MP0002733_abnormal_thermal_nociception1.18977928
72MP0004215_abnormal_myocardial_fiber1.18304312
73MP0001905_abnormal_dopamine_level1.17594859
74MP0002736_abnormal_nociception_after1.17366342
75MP0001502_abnormal_circadian_rhythm1.17295938
76MP0005253_abnormal_eye_physiology1.17178897
77MP0002249_abnormal_larynx_morphology1.15949829
78MP0002837_dystrophic_cardiac_calcinosis1.15844711
79MP0003279_aneurysm1.15379351
80MP0004859_abnormal_synaptic_plasticity1.14424883
81MP0002295_abnormal_pulmonary_circulatio1.13220061
82MP0000566_synostosis1.12973583
83MP0004142_abnormal_muscle_tone1.12193331
84MP0001177_atelectasis1.10553757
85MP0002734_abnormal_mechanical_nocicepti1.09079659
86MP0004147_increased_porphyrin_level1.08972307
87MP0000049_abnormal_middle_ear1.08090264
88MP0006138_congestive_heart_failure1.07590446
89MP0005248_abnormal_Harderian_gland1.03063026
90MP0003283_abnormal_digestive_organ1.01546028
91MP0002108_abnormal_muscle_morphology0.99579554
92MP0002272_abnormal_nervous_system0.99440404
93MP0005394_taste/olfaction_phenotype0.99366363
94MP0005499_abnormal_olfactory_system0.99366363
95MP0003385_abnormal_body_wall0.99287302
96MP0002229_neurodegeneration0.99079927
97MP0003690_abnormal_glial_cell0.97504638
98MP0001970_abnormal_pain_threshold0.97289594
99MP0002113_abnormal_skeleton_development0.97150734
100MP0002109_abnormal_limb_morphology0.96082375
101MP0003861_abnormal_nervous_system0.95514708
102MP0001440_abnormal_grooming_behavior0.95063319
103MP0005275_abnormal_skin_tensile0.94946282
104MP0002184_abnormal_innervation0.94434406
105MP0001958_emphysema0.93552384
106MP0003634_abnormal_glial_cell0.93548498
107MP0005620_abnormal_muscle_contractility0.93547540
108MP0002932_abnormal_joint_morphology0.93344928
109MP0002127_abnormal_cardiovascular_syste0.93089219
110MP0004085_abnormal_heartbeat0.92968765
111MP0004145_abnormal_muscle_electrophysio0.92583981
112MP0005386_behavior/neurological_phenoty0.91785051
113MP0004924_abnormal_behavior0.91785051
114MP0002116_abnormal_craniofacial_bone0.88974869
115MP0004742_abnormal_vestibular_system0.88868513
116MP0005165_increased_susceptibility_to0.88828633
117MP0006276_abnormal_autonomic_nervous0.88352961
118MP0000920_abnormal_myelination0.87335749
119MP0003787_abnormal_imprinting0.86757116
120MP0008438_abnormal_cutaneous_collagen0.86642612
121MP0000747_muscle_weakness0.85285135
122MP0000749_muscle_degeneration0.84846540
123MP0000230_abnormal_systemic_arterial0.83471245
124MP0000604_amyloidosis0.83384608
125MP0002752_abnormal_somatic_nervous0.82704782
126MP0002909_abnormal_adrenal_gland0.82422627
127MP0008789_abnormal_olfactory_epithelium0.82362239
128MP0003938_abnormal_ear_development0.80998650
129MP0002009_preneoplasia0.79271974
130MP0010678_abnormal_skin_adnexa0.78957103
131MP0002067_abnormal_sensory_capabilities0.78831671
132MP0008775_abnormal_heart_ventricle0.78542915
133MP0002233_abnormal_nose_morphology0.77877974
134MP0005385_cardiovascular_system_phenoty0.76702973
135MP0001544_abnormal_cardiovascular_syste0.76702973
136MP0000767_abnormal_smooth_muscle0.76465025
137MP0002064_seizures0.76425617
138MP0003635_abnormal_synaptic_transmissio0.75758885
139MP0005330_cardiomyopathy0.75699064
140MP0005646_abnormal_pituitary_gland0.74314969
141MP0005390_skeleton_phenotype0.73172655
142MP0002938_white_spotting0.71178820
143MP0005164_abnormal_response_to0.71056468
144MP0004043_abnormal_pH_regulation0.71005042
145MP0002128_abnormal_blood_circulation0.70136256
146MP0000383_abnormal_hair_follicle0.69199621
147MP0005171_absent_coat_pigmentation0.69023303
148MP0003121_genomic_imprinting0.68235829
149MP0004130_abnormal_muscle_cell0.67504997
150MP0003137_abnormal_impulse_conducting0.66989216
151MP0005391_vision/eye_phenotype0.66543250
152MP0009379_abnormal_foot_pigmentation0.65970454
153MP0002102_abnormal_ear_morphology0.65367084
154MP0001943_abnormal_respiration0.63995281
155MP0002069_abnormal_eating/drinking_beha0.61212588
156MP0001293_anophthalmia0.61146608

Predicted human phenotypes

RankGene SetZ-score
1Epiphyseal dysplasia (HP:0002656)8.60383428
2Hypoplastic ischia (HP:0003175)6.51050382
3Aplasia/Hypoplasia of the pubic bone (HP:0009104)6.39774593
4Irregular epiphyses (HP:0010582)6.30140851
5Vitreoretinal degeneration (HP:0000655)6.25724657
6Abnormality of the ischium (HP:0003174)6.08152501
7Focal motor seizures (HP:0011153)4.57146861
8Abnormality of binocular vision (HP:0011514)3.98542648
9Diplopia (HP:0000651)3.98542648
10Focal seizures (HP:0007359)3.94790012
11Abnormality of the pubic bones (HP:0003172)3.93568126
12Atonic seizures (HP:0010819)3.90261303
13Small epiphyses (HP:0010585)3.86233678
14Peripheral hypomyelination (HP:0007182)3.85624091
15Hemiparesis (HP:0001269)3.83390648
16Delayed epiphyseal ossification (HP:0002663)3.82490711
17Mixed hearing impairment (HP:0000410)3.68667320
18Genu varum (HP:0002970)3.51716492
19Abnormal tarsal ossification (HP:0008369)3.46748843
20Hemiplegia (HP:0002301)3.45901805
21Neonatal short-limb short stature (HP:0008921)3.44674891
22Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)3.42261882
23Absent epiphyses (HP:0010577)3.42261882
24Osteoarthritis (HP:0002758)3.41349946
25Protuberant abdomen (HP:0001538)3.34179458
26Mild short stature (HP:0003502)3.32940558
27Cupped ribs (HP:0000887)3.30121608
28Generalized tonic-clonic seizures (HP:0002069)3.18066836
29Abnormality of the vitreous humor (HP:0004327)3.10301360
30Enlarged epiphyses (HP:0010580)3.05611311
31Limited hip movement (HP:0008800)3.00304700
32Severe Myopia (HP:0011003)2.96675669
33Flat capital femoral epiphysis (HP:0003370)2.95603264
34Febrile seizures (HP:0002373)2.92169923
35Morphological abnormality of the inner ear (HP:0011390)2.91922122
36Abnormality involving the epiphyses of the lower limbs (HP:0006500)2.89282569
37Abnormality of femoral epiphyses (HP:0006499)2.89282569
38Epileptic encephalopathy (HP:0200134)2.88442889
39Split foot (HP:0001839)2.87710914
40Abnormal vertebral ossification (HP:0100569)2.87578934
41Metaphyseal dysplasia (HP:0100255)2.86440483
42Supranuclear gaze palsy (HP:0000605)2.86170809
43Alacrima (HP:0000522)2.78508568
44Flat acetabular roof (HP:0003180)2.77781230
45Increased circulating renin level (HP:0000848)2.76636606
46Cerebral hypomyelination (HP:0006808)2.74979652
47Abnormality of cochlea (HP:0000375)2.71222516
48Insomnia (HP:0100785)2.69364671
49Exostoses (HP:0100777)2.66399192
50Abnormality of the epiphysis of the femoral head (HP:0010574)2.64891075
51Absence seizures (HP:0002121)2.64010482
52Abnormality of the middle phalanges of the toes (HP:0010183)2.62045532
53Gait imbalance (HP:0002141)2.61604023
54Aplasia involving bones of the upper limbs (HP:0009823)2.60599450
55Aplasia of the phalanges of the hand (HP:0009802)2.60599450
56Aplasia involving bones of the extremities (HP:0009825)2.60599450
57Vertebral clefting (HP:0008428)2.60412656
58Abnormal eating behavior (HP:0100738)2.59853834
59Metaphyseal cupping (HP:0003021)2.53521502
60Dialeptic seizures (HP:0011146)2.52062255
61Hip contracture (HP:0003273)2.50164382
62Abnormality of the femoral head (HP:0003368)2.49560068
63Abnormality of the diencephalon (HP:0010662)2.48617155
64Flattened epiphyses (HP:0003071)2.48569511
65Synostosis involving the elbow (HP:0003938)2.43079190
66Humeroradial synostosis (HP:0003041)2.43079190
67Platyspondyly (HP:0000926)2.42611668
68Abnormality of the proximal phalanges of the hand (HP:0009834)2.41001938
69Status epilepticus (HP:0002133)2.39700474
70Neurofibrillary tangles (HP:0002185)2.36799749
71Ankle clonus (HP:0011448)2.35323012
72Lumbar hyperlordosis (HP:0002938)2.28999557
73Aplasia/Hypoplasia involving the pelvis (HP:0009103)2.28712246
74Abnormality of the vertebral endplates (HP:0005106)2.27794307
75Abnormality of the corticospinal tract (HP:0002492)2.27473900
76Barrel-shaped chest (HP:0001552)2.24977329
77Spastic tetraparesis (HP:0001285)2.24021461
78Termporal pattern (HP:0011008)2.22641091
79Insidious onset (HP:0003587)2.22641091
80Arterial tortuosity (HP:0005116)2.22061635
81Bowel incontinence (HP:0002607)2.19711990
82Spastic gait (HP:0002064)2.18468552
83Truncal ataxia (HP:0002078)2.18278645
84CNS hypomyelination (HP:0003429)2.17246771
85Abnormality of the phalanges of the 2nd finger (HP:0009541)2.16632491
86Muscle fiber splitting (HP:0003555)2.16313153
87Hypoplasia of the iris (HP:0007676)2.16002717
88Short femoral neck (HP:0100864)2.15173840
89Postural instability (HP:0002172)2.14670148
90Cortical dysplasia (HP:0002539)2.13795960
91Cutaneous finger syndactyly (HP:0010554)2.11891512
92Truncus arteriosus (HP:0001660)2.11527153
93Decreased lacrimation (HP:0000633)2.10221621
94Arthropathy (HP:0003040)2.09673481
95Abnormal foot bone ossification (HP:0010675)2.09326426
96Dysdiadochokinesis (HP:0002075)2.07008321
97Thoracolumbar scoliosis (HP:0002944)2.05947730
98Congenital primary aphakia (HP:0007707)2.05897349
99Tetraplegia (HP:0002445)2.04692680
100Obstructive sleep apnea (HP:0002870)2.04488567
101Sprengel anomaly (HP:0000912)2.04426477
102Megalencephaly (HP:0001355)2.04278147
103Limb dystonia (HP:0002451)2.00945758
104Cerebral hemorrhage (HP:0001342)2.00059506
105Hyperventilation (HP:0002883)1.99967541
106Facial shape deformation (HP:0011334)1.99342145
107Potter facies (HP:0002009)1.99342145
108Waddling gait (HP:0002515)1.98077112
109Abnormality of the lumbar spine (HP:0100712)1.97907085
110Mesangial abnormality (HP:0001966)1.96942649
111Anomalous pulmonary venous return (HP:0010772)1.96578605
112Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)1.95407085
113Degeneration of the lateral corticospinal tracts (HP:0002314)1.95407085
114Overriding aorta (HP:0002623)1.94942265
115Progressive cerebellar ataxia (HP:0002073)1.94164363
116Abnormal large intestine physiology (HP:0012700)1.93770828
117Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.93712806
118Vascular tortuosity (HP:0004948)1.92856033
119Micromelia (HP:0002983)1.91834593
120Exercise-induced muscle cramps (HP:0003710)1.90802492
121Dysmetria (HP:0001310)1.90665701
122Bell-shaped thorax (HP:0001591)1.90518578
123Vertebral arch anomaly (HP:0008438)1.88106836
124Knee flexion contracture (HP:0006380)1.86355675
125Medial flaring of the eyebrow (HP:0010747)1.85981461
126Cerebral inclusion bodies (HP:0100314)1.84044291
127Nephrogenic diabetes insipidus (HP:0009806)1.83892398
128Ulnar claw (HP:0001178)1.83649700
129Ovoid vertebral bodies (HP:0003300)1.83013616
130Abnormality of the pulmonary veins (HP:0011718)1.82746529
131Cutaneous syndactyly (HP:0012725)1.82458851
132Coxa vara (HP:0002812)1.82119762
133Hypoplastic pelvis (HP:0008839)1.81399614
134Turricephaly (HP:0000262)1.81368499
135Pheochromocytoma (HP:0002666)1.81260174
136Specific learning disability (HP:0001328)1.80803781
137Sleep apnea (HP:0010535)1.78068375
138Torticollis (HP:0000473)1.78032223
139Polyphagia (HP:0002591)1.77364719
140Intention tremor (HP:0002080)1.77248650
141Rhizomelia (HP:0008905)1.75941036
142Hypoplasia of the corpus callosum (HP:0002079)1.75706199
143Broad metatarsal (HP:0001783)1.75349975
144Partial duplication of thumb phalanx (HP:0009944)1.75308870
145Focal segmental glomerulosclerosis (HP:0000097)1.74964987
146Drooling (HP:0002307)1.74934723
147Absent speech (HP:0001344)1.74307558
148Retinal dysplasia (HP:0007973)1.73261745
149Hypoplasia of the ulna (HP:0003022)1.73018650
150Urinary bladder sphincter dysfunction (HP:0002839)1.71903367
151Papilledema (HP:0001085)1.71469800
152Aplasia/hypoplasia of the femur (HP:0005613)1.70104216
153Metaphyseal irregularity (HP:0003025)1.69771949
154Elfin facies (HP:0004428)1.67584792
155Myokymia (HP:0002411)1.67003696
156Bradykinesia (HP:0002067)1.66846966
157Depression (HP:0000716)1.66279770
158Aplasia/Hypoplasia of the phalanges of the toes (HP:0010173)1.65830371
159Thin ribs (HP:0000883)1.64044666
160Anterior segment dysgenesis (HP:0007700)1.63491890
161Glossoptosis (HP:0000162)1.63347292
162Tracheomalacia (HP:0002779)1.63278693
163Disproportionate tall stature (HP:0001519)1.63060390
164Spastic tetraplegia (HP:0002510)1.62909930
165Poor eye contact (HP:0000817)1.62469533
166Rib fusion (HP:0000902)1.62393479
167Thickened helices (HP:0000391)1.61968605
168Hyperthyroidism (HP:0000836)1.61864133
169Recurrent corneal erosions (HP:0000495)1.61494785
170Hammertoe (HP:0001765)1.61228974
171Cervical subluxation (HP:0003308)1.61121850
172Coronal craniosynostosis (HP:0004440)1.60981297
173Delusions (HP:0000746)1.60955495
174Abnormality of incisor morphology (HP:0011063)1.60915375
175Vaginal atresia (HP:0000148)1.60415691
176Poor coordination (HP:0002370)1.60130127
177Down-sloping shoulders (HP:0200021)1.59724344
178Impaired social interactions (HP:0000735)1.58983146
179Abnormal social behavior (HP:0012433)1.58983146
180Lower limb muscle weakness (HP:0007340)1.58826434
181Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.58103031
182Synostosis of carpal bones (HP:0005048)1.57909880
183Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.57252315
184Autoamputation (HP:0001218)1.57075041
185Short hallux (HP:0010109)1.56214113
186Action tremor (HP:0002345)1.54028005
187Abnormality of the phalanges of the 5th finger (HP:0004213)1.53763698

Predicted kinase interactions (KEA)

RankGene SetZ-score
1DDR26.11779082
2WNK43.32264303
3TIE13.18285789
4STK393.09357044
5TYRO32.74667236
6EPHB12.41128108
7LMTK22.20644375
8PHKG12.13819258
9PHKG22.13819258
10KDR2.00139062
11LATS11.90232270
12NTRK11.87271391
13PRKD31.85897208
14EPHB21.78484816
15PINK11.71065720
16SIK11.56654692
17OXSR11.55284812
18KSR21.54925698
19RIPK11.52735675
20DAPK21.50859767
21TNIK1.47316694
22PAK31.46462502
23STK38L1.45735600
24MAPK151.44905367
25LATS21.41031416
26GRK51.40005185
27FER1.38748235
28CAMKK11.34575340
29PAK61.33467834
30MAPKAPK51.30072127
31ICK1.28824074
32STK241.23931113
33PTK2B1.22233651
34PRKCG1.19034062
35CAMK2G1.17142947
36RET1.14849627
37CCNB11.12719350
38WNK11.09027418
39OBSCN1.08732389
40TRIB31.08376626
41NME11.02962473
42TGFBR21.02700852
43CDK151.01204400
44CAMK10.99457354
45MST40.99434670
46NEK60.97503405
47CDK180.96110747
48MAPK120.95769372
49CAMKK20.92650973
50SGK10.91944920
51CDK11A0.90965284
52SIK20.90842298
53MARK10.90762615
54SGK2230.89517351
55SGK4940.89517351
56EPHA30.89469076
57CDK140.88887745
58PDGFRA0.87383151
59NTRK30.83058421
60CSNK1A1L0.82349306
61FGFR30.82153551
62UHMK10.80987653
63GSK3A0.80027220
64ARAF0.80013954
65MKNK20.79358228
66PRKCE0.78540303
67PRKD10.77086938
68TRPM70.76751321
69PRKCH0.76678763
70PLK20.76297280
71MINK10.75418934
72MAPK100.75191045
73PRKG20.75189257
74CSNK1G10.74540286
75ROCK10.74062035
76DYRK20.73800094
77SGK30.73431791
78MYLK0.72956120
79MAP3K20.72743175
80MAP3K90.72223179
81CAMK2A0.70207519
82EPHA40.69627425
83MAP2K70.69447604
84PNCK0.68449730
85MET0.67267431
86STK30.66846903
87MAPK130.66622026
88RAF10.66108443
89CDK50.65472050
90CSNK1G20.64339655
91PTK60.64329089
92DMPK0.64006367
93NTRK20.63957084
94BRAF0.63945060
95MOS0.63897745
96ALK0.62950995
97MAP2K10.62041453
98PTK20.61148352
99MUSK0.61045352
100MARK30.60244748
101BRSK10.59712565
102ROCK20.59389169
103PDPK10.59163772
104PIK3CA0.58985652
105RPS6KA30.58840380
106ADRBK10.58778587
107DYRK1A0.58452955
108ERBB40.58395137
109ERBB20.58205737
110BCR0.57522421
111CAMK1G0.56679161
112CAMK40.55885376
113SGK20.52413771
114MAP3K40.52334537
115WNK30.52039005
116CAMK1D0.51701138
117CSNK1G30.51616868
118KSR10.51384690
119MAP2K40.50826646
120BMX0.49754762
121LIMK10.49529296
122PKN10.49235417
123MAP3K10.48051390
124FGFR40.47771252
125CSNK1D0.47525331
126STK380.46708818
127PRKG10.45860706
128PDK20.43799605
129PRKACA0.43715729
130PDGFRB0.43461214
131CASK0.42988393
132PRKDC0.42791289
133TAOK10.42727623
134MARK20.42707152
135IGF1R0.42545506
136FGFR20.42259865
137FGFR10.40983566
138MAPK70.40043972
139GSK3B0.39785314
140CAMK2B0.39461010
141CAMK2D0.39398411
142CSNK1E0.38659655
143PRKCZ0.36752728
144RPS6KB10.33777910
145MAP3K70.33147128
146PRKACG0.32976647

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.33183058
2ECM-receptor interaction_Homo sapiens_hsa045122.73384120
3Synaptic vesicle cycle_Homo sapiens_hsa047212.34568475
4Protein digestion and absorption_Homo sapiens_hsa049742.20050296
5Steroid biosynthesis_Homo sapiens_hsa001002.10148130
6Morphine addiction_Homo sapiens_hsa050322.06449315
7Synthesis and degradation of ketone bodies_Homo sapiens_hsa000722.03221601
8Nitrogen metabolism_Homo sapiens_hsa009101.98121993
9Dorso-ventral axis formation_Homo sapiens_hsa043201.96079732
10Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.90507918
11Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.80070822
12Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.68652125
13Fatty acid elongation_Homo sapiens_hsa000621.64036084
14Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.51088974
15Sulfur metabolism_Homo sapiens_hsa009201.50354120
16Focal adhesion_Homo sapiens_hsa045101.45450000
17Fatty acid metabolism_Homo sapiens_hsa012121.36495617
18Vasopressin-regulated water reabsorption_Homo sapiens_hsa049621.32722162
19Propanoate metabolism_Homo sapiens_hsa006401.32524677
20Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.29310272
21Dilated cardiomyopathy_Homo sapiens_hsa054141.27258672
22Axon guidance_Homo sapiens_hsa043601.26695990
23Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.26190595
24Fatty acid biosynthesis_Homo sapiens_hsa000611.20556264
25Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.20069147
26Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.13630048
27Hippo signaling pathway_Homo sapiens_hsa043901.10800260
28Bile secretion_Homo sapiens_hsa049761.09359897
29Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.07381609
30Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.05620512
31Butanoate metabolism_Homo sapiens_hsa006501.04967535
32Renal cell carcinoma_Homo sapiens_hsa052111.04542930
33Fatty acid degradation_Homo sapiens_hsa000711.03762836
34Basal cell carcinoma_Homo sapiens_hsa052171.00636750
35Melanogenesis_Homo sapiens_hsa049160.99971912
36Circadian rhythm_Homo sapiens_hsa047100.99631466
37beta-Alanine metabolism_Homo sapiens_hsa004100.98402545
38Insulin secretion_Homo sapiens_hsa049110.96089530
39Arginine biosynthesis_Homo sapiens_hsa002200.92774675
40Arginine and proline metabolism_Homo sapiens_hsa003300.90910615
41Prion diseases_Homo sapiens_hsa050200.90145127
42TGF-beta signaling pathway_Homo sapiens_hsa043500.89864051
43Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.88862335
44PPAR signaling pathway_Homo sapiens_hsa033200.88079130
45PI3K-Akt signaling pathway_Homo sapiens_hsa041510.87448116
46Gastric acid secretion_Homo sapiens_hsa049710.87322790
47Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.86530568
48Cocaine addiction_Homo sapiens_hsa050300.86198794
49Salivary secretion_Homo sapiens_hsa049700.85964462
50Cardiac muscle contraction_Homo sapiens_hsa042600.85155064
51Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.84926563
52Glutamatergic synapse_Homo sapiens_hsa047240.84072767
53Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.84045343
54Sphingolipid metabolism_Homo sapiens_hsa006000.83819293
55Ovarian steroidogenesis_Homo sapiens_hsa049130.83262199
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.83226805
57Circadian entrainment_Homo sapiens_hsa047130.83079533
58Vascular smooth muscle contraction_Homo sapiens_hsa042700.80497491
59Long-term depression_Homo sapiens_hsa047300.78645788
60Histidine metabolism_Homo sapiens_hsa003400.78461140
61Ether lipid metabolism_Homo sapiens_hsa005650.77737449
62Gap junction_Homo sapiens_hsa045400.77510616
63Renin secretion_Homo sapiens_hsa049240.77298431
64Oocyte meiosis_Homo sapiens_hsa041140.76860086
65Estrogen signaling pathway_Homo sapiens_hsa049150.75286494
66Pancreatic secretion_Homo sapiens_hsa049720.74962057
67Phosphatidylinositol signaling system_Homo sapiens_hsa040700.74636044
68Rap1 signaling pathway_Homo sapiens_hsa040150.74634038
69Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006300.74108663
70Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.73737700
71Cholinergic synapse_Homo sapiens_hsa047250.73130070
72AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.72732556
732-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.72648683
74Neurotrophin signaling pathway_Homo sapiens_hsa047220.71917753
75Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.71313926
76Hedgehog signaling pathway_Homo sapiens_hsa043400.70859566
77Endometrial cancer_Homo sapiens_hsa052130.70514742
78Carbohydrate digestion and absorption_Homo sapiens_hsa049730.70353526
79Notch signaling pathway_Homo sapiens_hsa043300.70224430
80GABAergic synapse_Homo sapiens_hsa047270.70010539
81Taste transduction_Homo sapiens_hsa047420.69942221
82Vitamin B6 metabolism_Homo sapiens_hsa007500.68798159
83Proteoglycans in cancer_Homo sapiens_hsa052050.67996331
84cAMP signaling pathway_Homo sapiens_hsa040240.67177489
85Ras signaling pathway_Homo sapiens_hsa040140.66663597
86Wnt signaling pathway_Homo sapiens_hsa043100.66402800
87* Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.66318324
88Thyroid hormone synthesis_Homo sapiens_hsa049180.65922068
89Phospholipase D signaling pathway_Homo sapiens_hsa040720.65154700
90Aldosterone synthesis and secretion_Homo sapiens_hsa049250.65125597
91Collecting duct acid secretion_Homo sapiens_hsa049660.64535086
92Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.63765573
93Glioma_Homo sapiens_hsa052140.63443256
94Adherens junction_Homo sapiens_hsa045200.62530100
95Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.62006586
96Serotonergic synapse_Homo sapiens_hsa047260.61977783
97Calcium signaling pathway_Homo sapiens_hsa040200.61494707
98Vibrio cholerae infection_Homo sapiens_hsa051100.60929351
99Primary bile acid biosynthesis_Homo sapiens_hsa001200.60553473
100Mineral absorption_Homo sapiens_hsa049780.59914652
101Amphetamine addiction_Homo sapiens_hsa050310.59488093
102GnRH signaling pathway_Homo sapiens_hsa049120.58695547
103Biosynthesis of amino acids_Homo sapiens_hsa012300.58327691
104Thyroid hormone signaling pathway_Homo sapiens_hsa049190.57474383
105Complement and coagulation cascades_Homo sapiens_hsa046100.57255196
106Dopaminergic synapse_Homo sapiens_hsa047280.56727528
107Tight junction_Homo sapiens_hsa045300.55722524
108Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.55524596
109Choline metabolism in cancer_Homo sapiens_hsa052310.54790938
110Amoebiasis_Homo sapiens_hsa051460.54757469
111Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.54327560
112VEGF signaling pathway_Homo sapiens_hsa043700.54228778
113Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.53757661
114Oxytocin signaling pathway_Homo sapiens_hsa049210.53754248
115Sphingolipid signaling pathway_Homo sapiens_hsa040710.53403772
116Phototransduction_Homo sapiens_hsa047440.53039204
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.51563573
118Insulin resistance_Homo sapiens_hsa049310.49168892
119Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.47420704
120ErbB signaling pathway_Homo sapiens_hsa040120.47160442
121MAPK signaling pathway_Homo sapiens_hsa040100.46756059
122Peroxisome_Homo sapiens_hsa041460.46638604
123Long-term potentiation_Homo sapiens_hsa047200.46371316
124Olfactory transduction_Homo sapiens_hsa047400.45948981
125Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.45662587
126Glucagon signaling pathway_Homo sapiens_hsa049220.44870822
127ABC transporters_Homo sapiens_hsa020100.42748870
128Type II diabetes mellitus_Homo sapiens_hsa049300.41586626
129Carbon metabolism_Homo sapiens_hsa012000.41095316
130Melanoma_Homo sapiens_hsa052180.40801111

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