COMMD10

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1attachment of spindle microtubules to kinetochore (GO:0008608)5.52992928
2cullin deneddylation (GO:0010388)4.58558318
3establishment of integrated proviral latency (GO:0075713)4.43214719
4DNA strand elongation involved in DNA replication (GO:0006271)4.42955859
5protein deneddylation (GO:0000338)4.42390204
6telomere maintenance via semi-conservative replication (GO:0032201)4.40960200
7protein neddylation (GO:0045116)4.40749782
8purine nucleobase biosynthetic process (GO:0009113)4.36830404
9DNA strand elongation (GO:0022616)4.22757218
10negative regulation of translation involved in gene silencing by miRNA (GO:0035278)4.22017684
11negative regulation of translation, ncRNA-mediated (GO:0040033)4.22017684
12regulation of translation, ncRNA-mediated (GO:0045974)4.22017684
13nucleobase biosynthetic process (GO:0046112)4.19049972
14proteasome assembly (GO:0043248)4.17619565
15telomere maintenance via recombination (GO:0000722)4.15249835
16DNA replication checkpoint (GO:0000076)4.10210539
17negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)4.08662225
18mitochondrial ATP synthesis coupled proton transport (GO:0042776)4.00726111
19DNA deamination (GO:0045006)4.00446053
20negative regulation of DNA-dependent DNA replication (GO:2000104)3.99972021
21respiratory chain complex IV assembly (GO:0008535)3.93134603
22DNA replication initiation (GO:0006270)3.91619253
23positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437)3.89971959
24regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.89619133
25mitotic metaphase plate congression (GO:0007080)3.85974650
26formation of translation preinitiation complex (GO:0001731)3.85388584
27anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:03.84168635
28water-soluble vitamin biosynthetic process (GO:0042364)3.83669857
29mitotic recombination (GO:0006312)3.83089419
30nuclear pore organization (GO:0006999)3.76750971
31IMP biosynthetic process (GO:0006188)3.71587627
32DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:003.69754088
33ribosomal small subunit assembly (GO:0000028)3.68322867
34signal transduction involved in mitotic DNA damage checkpoint (GO:1902402)3.66114613
35signal transduction involved in mitotic cell cycle checkpoint (GO:0072413)3.66114613
36signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403)3.66114613
37intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400)3.65630505
38signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431)3.65630505
39regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)3.64381656
40regulation of mitotic spindle checkpoint (GO:1903504)3.64381656
41negative regulation of ligase activity (GO:0051352)3.63532548
42negative regulation of ubiquitin-protein transferase activity (GO:0051444)3.63532548
43telomere maintenance via telomere lengthening (GO:0010833)3.62364184
44nucleotide-excision repair, DNA gap filling (GO:0006297)3.62163162
45metaphase plate congression (GO:0051310)3.59973047
46signal transduction involved in DNA integrity checkpoint (GO:0072401)3.56848906
47signal transduction involved in DNA damage checkpoint (GO:0072422)3.56848906
48signal transduction involved in cell cycle checkpoint (GO:0072395)3.54656082
49folic acid-containing compound biosynthetic process (GO:0009396)3.53309974
50pteridine-containing compound biosynthetic process (GO:0042559)3.53026414
51heart process (GO:0003015)3.52244785
52heart contraction (GO:0060047)3.52244785
53CENP-A containing nucleosome assembly (GO:0034080)3.52119039
54exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay 3.49916752
55positive regulation of ubiquitin-protein transferase activity (GO:0051443)3.49209506
56antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:3.48069302
57nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291)3.47703218
58ribosome biogenesis (GO:0042254)3.46419677
59establishment of viral latency (GO:0019043)3.44026459
60cytochrome complex assembly (GO:0017004)3.42961817
61establishment of protein localization to mitochondrial membrane (GO:0090151)3.41342156
62chromatin remodeling at centromere (GO:0031055)3.39687570
63lactate metabolic process (GO:0006089)3.39195824
64mitochondrial electron transport, NADH to ubiquinone (GO:0006120)3.38713389
65kinetochore organization (GO:0051383)3.36484603
66establishment of chromosome localization (GO:0051303)3.36252710
67antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)3.34927976
68positive regulation of ligase activity (GO:0051351)3.32429243
69histone exchange (GO:0043486)3.32295379
70transcription-coupled nucleotide-excision repair (GO:0006283)3.31940205
71energy coupled proton transport, down electrochemical gradient (GO:0015985)3.29572601
72ATP synthesis coupled proton transport (GO:0015986)3.29572601
73pseudouridine synthesis (GO:0001522)3.29197196
74cell cycle G1/S phase transition (GO:0044843)3.28641729
75G1/S transition of mitotic cell cycle (GO:0000082)3.28641729
76regulation of double-strand break repair via homologous recombination (GO:0010569)3.27736607
77regulation of cellular amino acid metabolic process (GO:0006521)3.26534010
78kinetochore assembly (GO:0051382)3.25595702
79histone mRNA metabolic process (GO:0008334)3.25487419
80microtubule cytoskeleton organization involved in mitosis (GO:1902850)3.25233588
81rRNA modification (GO:0000154)3.23204049
82RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.20876480
837-methylguanosine mRNA capping (GO:0006370)3.18712301
84protein complex biogenesis (GO:0070271)3.17993065
85somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.17264024
86somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.17264024
87isotype switching (GO:0045190)3.17264024
88spliceosomal snRNP assembly (GO:0000387)3.16116196
89regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)3.15401393
90L-methionine biosynthetic process from methylthioadenosine (GO:0019509)3.13622465
91deoxyribonucleotide biosynthetic process (GO:0009263)3.12893343
927-methylguanosine RNA capping (GO:0009452)3.12302770
93RNA capping (GO:0036260)3.12302770
94somatic hypermutation of immunoglobulin genes (GO:0016446)3.11141543
95somatic diversification of immune receptors via somatic mutation (GO:0002566)3.11141543
96mitochondrial respiratory chain complex assembly (GO:0033108)3.11004472
97positive regulation of cell cycle arrest (GO:0071158)3.10247914
98viral mRNA export from host cell nucleus (GO:0046784)3.09905895
99maturation of SSU-rRNA (GO:0030490)3.09237530
100sequestering of actin monomers (GO:0042989)3.09025412
101IMP metabolic process (GO:0046040)3.07751759
102DNA ligation (GO:0006266)3.07573510
103transcription elongation from RNA polymerase III promoter (GO:0006385)3.07302567
104termination of RNA polymerase III transcription (GO:0006386)3.07302567
105DNA damage response, signal transduction by p53 class mediator (GO:0030330)3.06669241
106telomere maintenance (GO:0000723)3.06109567
107telomere organization (GO:0032200)3.05948461
108RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394)3.05698010
109tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388)3.05698010
110DNA double-strand break processing (GO:0000729)3.04492565
111synapsis (GO:0007129)3.03094654
112regulation of ubiquitin-protein transferase activity (GO:0051438)3.02443092
113mitotic nuclear envelope disassembly (GO:0007077)3.02342923
114meiotic chromosome segregation (GO:0045132)3.01981332
115transcription from RNA polymerase I promoter (GO:0006360)3.00860259
116production of molecular mediator involved in inflammatory response (GO:0002532)3.00768444
117resolution of meiotic recombination intermediates (GO:0000712)3.00730844
118ribonucleoprotein complex biogenesis (GO:0022613)3.00669034
119maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)3.00484307
120replication fork processing (GO:0031297)2.99992381
121chaperone-mediated protein transport (GO:0072321)2.99559990
122regulation of meiosis I (GO:0060631)2.96181736
123deoxyribonucleoside monophosphate metabolic process (GO:0009162)2.95050370
124platelet dense granule organization (GO:0060155)2.95047989
125nucleobase-containing small molecule interconversion (GO:0015949)2.94845371
126DNA replication-dependent nucleosome assembly (GO:0006335)2.93236571
127DNA replication-dependent nucleosome organization (GO:0034723)2.93236571
128protein localization to kinetochore (GO:0034501)2.92943004
129DNA replication-independent nucleosome assembly (GO:0006336)2.92154787
130DNA replication-independent nucleosome organization (GO:0034724)2.92154787
131DNA unwinding involved in DNA replication (GO:0006268)2.91128114
132regulation of ligase activity (GO:0051340)2.90401662
133ribosome assembly (GO:0042255)2.86712034
134response to X-ray (GO:0010165)2.86410413
135maturation of 5.8S rRNA (GO:0000460)2.85949679
136mitochondrial respiratory chain complex I assembly (GO:0032981)2.85293096
137NADH dehydrogenase complex assembly (GO:0010257)2.85293096
138mitochondrial respiratory chain complex I biogenesis (GO:0097031)2.85293096
139intra-S DNA damage checkpoint (GO:0031573)2.84512275
140respiratory electron transport chain (GO:0022904)2.83408875
141non-recombinational repair (GO:0000726)2.82962731
142double-strand break repair via nonhomologous end joining (GO:0006303)2.82962731
143DNA catabolic process, exonucleolytic (GO:0000738)2.82328901
144regulation of helicase activity (GO:0051095)2.81893947
145deoxyribose phosphate biosynthetic process (GO:0046385)2.81450573
1462-deoxyribonucleotide biosynthetic process (GO:0009265)2.81450573
147antigen processing and presentation of peptide antigen via MHC class I (GO:0002474)2.79964752
148regulation of DNA endoreduplication (GO:0032875)2.79292339
149negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.79147261
150rRNA processing (GO:0006364)2.79141854
151postreplication repair (GO:0006301)2.78739523
152electron transport chain (GO:0022900)2.78271593
153negative regulation of mitotic sister chromatid segregation (GO:0033048)2.78064937
154branched-chain amino acid catabolic process (GO:0009083)2.75873785
155spindle checkpoint (GO:0031577)2.70199260

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.66647032
2MYC_18555785_ChIP-Seq_MESCs_Mouse4.12887376
3KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human3.73226418
4EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.40394277
5EST1_17652178_ChIP-ChIP_JURKAT_Human3.35386652
6GABP_17652178_ChIP-ChIP_JURKAT_Human3.28077966
7JARID1A_20064375_ChIP-Seq_MESCs_Mouse3.14341189
8E2F4_17652178_ChIP-ChIP_JURKAT_Human3.13591846
9NOTCH1_17114293_ChIP-ChIP_T-ALL_Human3.03984717
10CREB1_15753290_ChIP-ChIP_HEK293T_Human2.89638934
11ETS1_20019798_ChIP-Seq_JURKAT_Human2.85700162
12* MYC_18358816_ChIP-ChIP_MESCs_Mouse2.85310577
13MYC_19030024_ChIP-ChIP_MESCs_Mouse2.83936263
14MYC_19079543_ChIP-ChIP_MESCs_Mouse2.71546016
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.70297488
16CHD1_19587682_ChIP-ChIP_MESCs_Mouse2.63207218
17NELFA_20434984_ChIP-Seq_ESCs_Mouse2.52689420
18FOXM1_23109430_ChIP-Seq_U2OS_Human2.46313301
19HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.40775368
20* E2F1_18555785_ChIP-Seq_MESCs_Mouse2.35881839
21FLI1_27457419_Chip-Seq_LIVER_Mouse2.35804034
22ZNF274_21170338_ChIP-Seq_K562_Hela2.34522077
23ELF1_17652178_ChIP-ChIP_JURKAT_Human2.27389702
24VDR_23849224_ChIP-Seq_CD4+_Human2.26554622
25VDR_22108803_ChIP-Seq_LS180_Human2.25499104
26EWS_26573619_Chip-Seq_HEK293_Human2.23558053
27* POU3F2_20337985_ChIP-ChIP_501MEL_Human2.22284312
28XRN2_22483619_ChIP-Seq_HELA_Human2.17804867
29HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.16623956
30SRF_21415370_ChIP-Seq_HL-1_Mouse2.07902462
31PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse2.07190551
32ELK1_19687146_ChIP-ChIP_HELA_Human2.03952329
33DCP1A_22483619_ChIP-Seq_HELA_Human2.02737012
34MYBL2_22936984_ChIP-ChIP_MESCs_Mouse2.02034046
35MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.97222013
36NANOG_18555785_ChIP-Seq_MESCs_Mouse1.96650893
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.93293489
38ZFP57_27257070_Chip-Seq_ESCs_Mouse1.89260595
39FUS_26573619_Chip-Seq_HEK293_Human1.88369136
40P300_19829295_ChIP-Seq_ESCs_Human1.86306422
41FOXP3_21729870_ChIP-Seq_TREG_Human1.84853487
42AR_21909140_ChIP-Seq_LNCAP_Human1.83194128
43TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat1.82972675
44GABP_19822575_ChIP-Seq_HepG2_Human1.81776522
45YY1_21170310_ChIP-Seq_MESCs_Mouse1.81453752
46PCGF2_27294783_Chip-Seq_ESCs_Mouse1.79820851
47* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.75405362
48HOXB4_20404135_ChIP-ChIP_EML_Mouse1.71646328
49TAF15_26573619_Chip-Seq_HEK293_Human1.70401679
50POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.70361062
51* MYCN_18555785_ChIP-Seq_MESCs_Mouse1.69723077
52FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.68962910
53TTF2_22483619_ChIP-Seq_HELA_Human1.67971363
54E2F1_21310950_ChIP-Seq_MCF-7_Human1.67907377
55POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.64542201
56IGF1R_20145208_ChIP-Seq_DFB_Human1.62685313
57YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.60430873
58PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.58800170
59POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.56503748
60EGR1_19374776_ChIP-ChIP_THP-1_Human1.54466155
61NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.54397809
62ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.54156943
63GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.51389783
64CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.50920891
65RBPJ_22232070_ChIP-Seq_NCS_Mouse1.50772350
66CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.50414558
67E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.49365886
68TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.49059396
69FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.48430502
70KDM5B_21448134_ChIP-Seq_MESCs_Mouse1.45980726
71KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.45637155
72KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.45637155
73KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.45637155
74FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.44231000
75TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.37396692
76RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse1.37188032
77IRF8_21731497_ChIP-ChIP_J774_Mouse1.37161698
78CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.36967464
79SUZ12_27294783_Chip-Seq_NPCs_Mouse1.36601029
80ZFX_18555785_ChIP-Seq_MESCs_Mouse1.36026654
81TFEB_21752829_ChIP-Seq_HELA_Human1.35328822
82EZH2_27294783_Chip-Seq_NPCs_Mouse1.29791171
83* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.29675038
84STAT3_1855785_ChIP-Seq_MESCs_Mouse1.28460924
85SOX2_18555785_ChIP-Seq_MESCs_Mouse1.27745752
86GBX2_23144817_ChIP-Seq_PC3_Human1.27690692
87* SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.27638589
88* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.26693633
89EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.25435324
90SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.24706371
91* ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.24656428
92ERG_20887958_ChIP-Seq_HPC-7_Mouse1.24642154
93NFE2_27457419_Chip-Seq_LIVER_Mouse1.23584232
94PCGF2_27294783_Chip-Seq_NPCs_Mouse1.22751258
95CTBP2_25329375_ChIP-Seq_LNCAP_Human1.21299550
96ELK1_22589737_ChIP-Seq_MCF10A_Human1.21043452
97GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.19845658
98MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.19742242
99SOX2_19829295_ChIP-Seq_ESCs_Human1.19266000
100NANOG_19829295_ChIP-Seq_ESCs_Human1.19266000
101RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.19220290
102MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.18916232
103ER_23166858_ChIP-Seq_MCF-7_Human1.15781457
104CIITA_25753668_ChIP-Seq_RAJI_Human1.15244768
105* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.15120658
106SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.14092709
107NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.13551742
108PADI4_21655091_ChIP-ChIP_MCF-7_Human1.11766516
109GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse1.10744295
110UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.09958332
111CTBP1_25329375_ChIP-Seq_LNCAP_Human1.09536739
112KDM5A_27292631_Chip-Seq_BREAST_Human1.09363583
113CBP_20019798_ChIP-Seq_JUKART_Human1.08419356
114IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.08419356
115BCAT_22108803_ChIP-Seq_LS180_Human1.07198292
116KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05956672
117ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.05897333
118* MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.05886046
119NANOG_18555785_Chip-Seq_ESCs_Mouse1.05769410
120POU5F1_16153702_ChIP-ChIP_HESCs_Human1.05074288
121IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.05050920
122TCF3_18692474_ChIP-Seq_MEFs_Mouse1.04634908
123IRF1_19129219_ChIP-ChIP_H3396_Human1.04233616
124CDX2_22108803_ChIP-Seq_LS180_Human1.04062689
125CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.03992930
126NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.03055543
127ELF5_23300383_ChIP-Seq_T47D_Human1.02892699
128TP63_19390658_ChIP-ChIP_HaCaT_Human1.02710958
129CRX_20693478_ChIP-Seq_RETINA_Mouse1.02450471
130KLF5_20875108_ChIP-Seq_MESCs_Mouse1.01702937
131* SMAD4_21799915_ChIP-Seq_A2780_Human1.00713583
132TCF4_22108803_ChIP-Seq_LS180_Human1.00492910
133NANOG_16153702_ChIP-ChIP_HESCs_Human1.00106447
134KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.99588747
135SOX2_18692474_ChIP-Seq_MEFs_Mouse0.99349319
136* SPI1_23547873_ChIP-Seq_NB4_Human0.98999204
137HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.98848514
138NOTCH1_21737748_ChIP-Seq_TLL_Human0.97896821
139TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.97498946
140PIAS1_25552417_ChIP-Seq_VCAP_Human0.97031396
141DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.95856858
142BCL3_23251550_ChIP-Seq_MUSCLE_Mouse0.95200967
143HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse0.95121291
144HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse0.94517424
145KLF4_18555785_ChIP-Seq_MESCs_Mouse0.94437669
146E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human0.93492953
147* SOX17_20123909_ChIP-Seq_XEN_Mouse0.91887164
148MYC_18940864_ChIP-ChIP_HL60_Human0.90032004
149SALL1_21062744_ChIP-ChIP_HESCs_Human0.88868930
150CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.88182265
151OCT4_18692474_ChIP-Seq_MEFs_Mouse0.88127126
152CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human0.86199149
153GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.82556091

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003693_abnormal_embryo_hatching4.67309735
2MP0010094_abnormal_chromosome_stability3.96153331
3MP0004957_abnormal_blastocyst_morpholog3.90363511
4MP0008058_abnormal_DNA_repair3.57176597
5MP0003077_abnormal_cell_cycle3.45550967
6MP0008789_abnormal_olfactory_epithelium3.36434824
7MP0003111_abnormal_nucleus_morphology3.27821988
8MP0002102_abnormal_ear_morphology3.27408719
9MP0008007_abnormal_cellular_replicative3.21247974
10MP0008057_abnormal_DNA_replication3.09064780
11MP0008932_abnormal_embryonic_tissue2.66678534
12MP0001529_abnormal_vocalization2.66226916
13MP0006072_abnormal_retinal_apoptosis2.59555445
14MP0003806_abnormal_nucleotide_metabolis2.43252237
15MP0002837_dystrophic_cardiac_calcinosis2.34718612
16MP0003186_abnormal_redox_activity2.29840843
17MP0003195_calcinosis2.27881804
18MP0003123_paternal_imprinting2.27725815
19MP0003941_abnormal_skin_development2.25656673
20MP0003011_delayed_dark_adaptation2.25445281
21MP0005394_taste/olfaction_phenotype2.21485174
22MP0005499_abnormal_olfactory_system2.21485174
23MP0003786_premature_aging2.13994437
24MP0005084_abnormal_gallbladder_morpholo2.06442481
25MP0005253_abnormal_eye_physiology1.94933423
26MP0001485_abnormal_pinna_reflex1.91312947
27MP0000372_irregular_coat_pigmentation1.76659093
28MP0009697_abnormal_copulation1.76328026
29MP0003718_maternal_effect1.76280987
30MP0006292_abnormal_olfactory_placode1.73003569
31MP0001730_embryonic_growth_arrest1.72019615
32MP0008877_abnormal_DNA_methylation1.71114037
33MP0000350_abnormal_cell_proliferation1.70827177
34MP0010030_abnormal_orbit_morphology1.68575071
35MP0001984_abnormal_olfaction1.64231681
36MP0002396_abnormal_hematopoietic_system1.59577110
37MP0002736_abnormal_nociception_after1.57619230
38MP0000569_abnormal_digit_pigmentation1.56583092
39MP0006036_abnormal_mitochondrial_physio1.55550622
40MP0000490_abnormal_crypts_of1.53061631
41MP0001835_abnormal_antigen_presentation1.49995985
42MP0004215_abnormal_myocardial_fiber1.48819614
43MP0005379_endocrine/exocrine_gland_phen1.48764033
44MP0010352_gastrointestinal_tract_polyps1.42960903
45MP0002090_abnormal_vision1.42855958
46MP0005551_abnormal_eye_electrophysiolog1.39666840
47MP0002751_abnormal_autonomic_nervous1.39511064
48MP0003121_genomic_imprinting1.38693737
49MP0005395_other_phenotype1.35444083
50MP0004084_abnormal_cardiac_muscle1.35391917
51MP0001764_abnormal_homeostasis1.30790419
52MP0000313_abnormal_cell_death1.30725873
53MP0001697_abnormal_embryo_size1.30407266
54MP0005332_abnormal_amino_acid1.30138573
55MP0000566_synostosis1.30129123
56MP0003950_abnormal_plasma_membrane1.29846146
57MP0003880_abnormal_central_pattern1.29160654
58MP0002254_reproductive_system_inflammat1.27377014
59MP0002148_abnormal_hypersensitivity_rea1.25548985
60MP0001672_abnormal_embryogenesis/_devel1.24561757
61MP0005380_embryogenesis_phenotype1.24561757
62MP0004145_abnormal_muscle_electrophysio1.22369672
63MP0002132_abnormal_respiratory_system1.21553193
64MP0002938_white_spotting1.20910809
65MP0008872_abnormal_physiological_respon1.20284844
66MP0002019_abnormal_tumor_incidence1.17394136
67MP0002233_abnormal_nose_morphology1.17203442
68MP0003890_abnormal_embryonic-extraembry1.16935481
69MP0006276_abnormal_autonomic_nervous1.12562324
70MP0000015_abnormal_ear_pigmentation1.11987977
71MP0009333_abnormal_splenocyte_physiolog1.11756490
72MP0001293_anophthalmia1.11163828
73MP0004808_abnormal_hematopoietic_stem1.11086900
74MP0000427_abnormal_hair_cycle1.10828538
75MP0003984_embryonic_growth_retardation1.10627478
76MP0005058_abnormal_lysosome_morphology1.09807954
77MP0004133_heterotaxia1.09773458
78MP0006035_abnormal_mitochondrial_morpho1.09641908
79MP0001853_heart_inflammation1.08952940
80MP0010307_abnormal_tumor_latency1.07930701
81MP0002080_prenatal_lethality1.07923059
82MP0004147_increased_porphyrin_level1.07238199
83MP0002638_abnormal_pupillary_reflex1.06242481
84MP0001929_abnormal_gametogenesis1.05990073
85MP0002088_abnormal_embryonic_growth/wei1.05732293
86MP0005503_abnormal_tendon_morphology1.03859009
87MP0000653_abnormal_sex_gland1.02914986
88MP0001119_abnormal_female_reproductive1.01906557
89MP0000343_altered_response_to1.01605472
90MP0009785_altered_susceptibility_to1.00268198
91MP0002210_abnormal_sex_determination0.99319490
92MP0005671_abnormal_response_to0.98846983
93MP0002085_abnormal_embryonic_tissue0.98835402
94MP0003448_altered_tumor_morphology0.98578848
95MP0005389_reproductive_system_phenotype0.96880971
96MP0003566_abnormal_cell_adhesion0.96128658
97MP0003315_abnormal_perineum_morphology0.95421782
98MP0008260_abnormal_autophagy0.95410605
99MP0002160_abnormal_reproductive_system0.94754877
100MP0002277_abnormal_respiratory_mucosa0.94100451
101MP0005023_abnormal_wound_healing0.93338260
102MP0005075_abnormal_melanosome_morpholog0.93226967
103MP0000858_altered_metastatic_potential0.92901450
104MP0005408_hypopigmentation0.92095278
105MP0008438_abnormal_cutaneous_collagen0.91912885
106MP0002086_abnormal_extraembryonic_tissu0.90212827
107MP0000358_abnormal_cell_content/0.89791057
108MP0003567_abnormal_fetal_cardiomyocyte0.89765020
109MP0008875_abnormal_xenobiotic_pharmacok0.88152843
110MP0003136_yellow_coat_color0.87825482
111MP0001968_abnormal_touch/_nociception0.87560544
112MP0009379_abnormal_foot_pigmentation0.87415136
113MP0006082_CNS_inflammation0.86238523
114MP0002084_abnormal_developmental_patter0.86077250
115MP0005174_abnormal_tail_pigmentation0.85739336
116MP0004197_abnormal_fetal_growth/weight/0.85572204
117MP0005391_vision/eye_phenotype0.85082543
118MP0001542_abnormal_bone_strength0.84715154
119MP0000049_abnormal_middle_ear0.84322226
120MP0010386_abnormal_urinary_bladder0.83619866
121MP0003763_abnormal_thymus_physiology0.83353970
122MP0003787_abnormal_imprinting0.82946366
123MP0002653_abnormal_ependyma_morphology0.82684732
124MP0005636_abnormal_mineral_homeostasis0.81703703
125MP0000689_abnormal_spleen_morphology0.81648676
126MP0005397_hematopoietic_system_phenotyp0.81578664
127MP0001545_abnormal_hematopoietic_system0.81578664
128MP0002163_abnormal_gland_morphology0.80807754
129MP0000749_muscle_degeneration0.80193844
130MP0001145_abnormal_male_reproductive0.80153978
131MP0005085_abnormal_gallbladder_physiolo0.79729719
132MP0002722_abnormal_immune_system0.79105862
133MP0002452_abnormal_antigen_presenting0.77264578
134MP0002398_abnormal_bone_marrow0.77143954
135MP0000516_abnormal_urinary_system0.75320676
136MP0005367_renal/urinary_system_phenotyp0.75320676
137MP0002405_respiratory_system_inflammati0.75317403
138MP0006054_spinal_hemorrhage0.74207424
139MP0001919_abnormal_reproductive_system0.73515783
140MP0002429_abnormal_blood_cell0.72277812
141MP0009780_abnormal_chondrocyte_physiolo0.71993952
142MP0000647_abnormal_sebaceous_gland0.71859367
143MP0005384_cellular_phenotype0.71825412
144MP0004782_abnormal_surfactant_physiolog0.71496302
145MP0001324_abnormal_eye_pigmentation0.71431201
146MP0000631_abnormal_neuroendocrine_gland0.69091690
147MP0002127_abnormal_cardiovascular_syste0.68832222
148MP0003937_abnormal_limbs/digits/tail_de0.68741949
149MP0003436_decreased_susceptibility_to0.68373120
150MP0003943_abnormal_hepatobiliary_system0.68263078
151MP0008995_early_reproductive_senescence0.68200148
152MP0002111_abnormal_tail_morphology0.68009641
153MP0001186_pigmentation_phenotype0.67861877
154MP0003221_abnormal_cardiomyocyte_apopto0.67056695
155MP0002095_abnormal_skin_pigmentation0.65988634
156MP0005410_abnormal_fertilization0.65561956
157MP0001819_abnormal_immune_cell0.65136094
158MP0005646_abnormal_pituitary_gland0.64965653
159MP0003698_abnormal_male_reproductive0.63774309
160MP0005220_abnormal_exocrine_pancreas0.63248580
161MP0008775_abnormal_heart_ventricle0.60546537
162MP0001177_atelectasis0.60490975
163MP0003122_maternal_imprinting0.59702764
164MP0001188_hyperpigmentation0.58309418

Predicted human phenotypes

RankGene SetZ-score
1Birth length less than 3rd percentile (HP:0003561)4.52337512
2Abnormality of the anterior horn cell (HP:0006802)3.85934653
3Degeneration of anterior horn cells (HP:0002398)3.85934653
4Chromsome breakage (HP:0040012)3.76254123
5Methylmalonic acidemia (HP:0002912)3.74012542
6Increased hepatocellular lipid droplets (HP:0006565)3.71998861
7Aplastic anemia (HP:0001915)3.71303006
8Acute necrotizing encephalopathy (HP:0006965)3.70606369
9Chromosomal breakage induced by crosslinking agents (HP:0003221)3.52392725
10Agnosia (HP:0010524)3.44554819
11Acute encephalopathy (HP:0006846)3.42332953
12Lipid accumulation in hepatocytes (HP:0006561)3.39377432
13Progressive macrocephaly (HP:0004481)3.38680636
14Breast hypoplasia (HP:0003187)3.37257371
15Mitochondrial inheritance (HP:0001427)3.33528249
16Increased CSF lactate (HP:0002490)3.28743250
17Type I transferrin isoform profile (HP:0003642)3.22429310
18Oral leukoplakia (HP:0002745)3.20839800
19Carpal bone hypoplasia (HP:0001498)3.13948446
20Meckel diverticulum (HP:0002245)3.13376663
21Abnormal mitochondria in muscle tissue (HP:0008316)3.09577192
22Cerebral hypomyelination (HP:0006808)3.08184379
23Abnormality of the ileum (HP:0001549)3.03778046
24Patellar aplasia (HP:0006443)3.03192465
25Abnormality of the preputium (HP:0100587)2.96960181
26Renal Fanconi syndrome (HP:0001994)2.93929537
27Aplasia/Hypoplasia of the patella (HP:0006498)2.91836525
28Rough bone trabeculation (HP:0100670)2.89391194
29Methylmalonic aciduria (HP:0012120)2.88225899
30Aplasia/Hypoplasia of the sacrum (HP:0008517)2.87869908
31Abnormality of methionine metabolism (HP:0010901)2.87236091
32Abnormality of chromosome stability (HP:0003220)2.84742729
33Abnormality of aspartate family amino acid metabolism (HP:0010899)2.83054683
34Premature graying of hair (HP:0002216)2.74113719
35Pancreatic cysts (HP:0001737)2.73677296
36Colon cancer (HP:0003003)2.71400671
37Selective tooth agenesis (HP:0001592)2.70928421
38Aplasia/Hypoplasia of the uvula (HP:0010293)2.70797697
39Absent radius (HP:0003974)2.69219992
40Hepatic necrosis (HP:0002605)2.68272801
41Cerebral edema (HP:0002181)2.67686271
42Reticulocytopenia (HP:0001896)2.64142710
43Pancreatic fibrosis (HP:0100732)2.63196457
44Abnormality of the labia minora (HP:0012880)2.62828671
45Hepatocellular necrosis (HP:0001404)2.61654163
46Poor head control (HP:0002421)2.58625906
47Irregular epiphyses (HP:0010582)2.58070807
48Neoplasm of the adrenal gland (HP:0100631)2.51575523
49Hyperglycinemia (HP:0002154)2.50345809
50Hypoglycemic coma (HP:0001325)2.49982671
51Hyperinsulinemic hypoglycemia (HP:0000825)2.49604150
52Abnormal lung lobation (HP:0002101)2.49496759
53Absent thumb (HP:0009777)2.48906287
54Supernumerary spleens (HP:0009799)2.44765644
55Absent forearm bone (HP:0003953)2.42974067
56Aplasia involving forearm bones (HP:0009822)2.42974067
57Bone marrow hypocellularity (HP:0005528)2.42826718
58Abnormal trabecular bone morphology (HP:0100671)2.41676729
59Small intestinal stenosis (HP:0012848)2.39636308
60Duodenal stenosis (HP:0100867)2.39636308
61Abnormality of vitamin B metabolism (HP:0004340)2.39621415
62Exertional dyspnea (HP:0002875)2.37334966
63Volvulus (HP:0002580)2.35877620
64True hermaphroditism (HP:0010459)2.35193345
65Medulloblastoma (HP:0002885)2.32221894
66Microretrognathia (HP:0000308)2.31159223
67Abnormality of serum amino acid levels (HP:0003112)2.28122380
6811 pairs of ribs (HP:0000878)2.27325854
69Reduced antithrombin III activity (HP:0001976)2.25538731
70Abnormality of the vitamin B12 metabolism (HP:0004341)2.24574797
71Intestinal atresia (HP:0011100)2.23467933
72Type 2 muscle fiber atrophy (HP:0003554)2.23250490
73Rectovaginal fistula (HP:0000143)2.22892139
74Rectal fistula (HP:0100590)2.22892139
75Myelodysplasia (HP:0002863)2.21720814
76Palpitations (HP:0001962)2.17783634
77Medial flaring of the eyebrow (HP:0010747)2.17603163
78Tongue fasciculations (HP:0001308)2.16884069
79Lactic acidosis (HP:0003128)2.16736805
80Rhabdomyosarcoma (HP:0002859)2.15172548
81Ependymoma (HP:0002888)2.13628982
82Aplasia/Hypoplasia involving the carpal bones (HP:0006502)2.13268320
83Hypoglycemic seizures (HP:0002173)2.12817854
84Abnormality of glycine metabolism (HP:0010895)2.12645155
85Abnormality of serine family amino acid metabolism (HP:0010894)2.12645155
86Neoplasm of the adrenal cortex (HP:0100641)2.12576544
87Abnormality of sulfur amino acid metabolism (HP:0004339)2.10623351
88Abnormality of midbrain morphology (HP:0002418)2.10455116
89Molar tooth sign on MRI (HP:0002419)2.10455116
90Abolished electroretinogram (ERG) (HP:0000550)2.08171968
91Hypothermia (HP:0002045)2.07470445
92Abnormal biliary tract physiology (HP:0012439)2.05120101
93Bile duct proliferation (HP:0001408)2.05120101
94Glioma (HP:0009733)2.05045997
95Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.04936674
96Decreased activity of mitochondrial respiratory chain (HP:0008972)2.04936674
97Tracheoesophageal fistula (HP:0002575)2.03601449
98Patent foramen ovale (HP:0001655)2.01230020
99Muscle fiber atrophy (HP:0100295)2.01028807
100Abnormality of renal resorption (HP:0011038)2.01005863
101Triphalangeal thumb (HP:0001199)2.00936509
102Congenital, generalized hypertrichosis (HP:0004540)2.00222064
103Abnormal gallbladder physiology (HP:0012438)2.00091532
104Cholecystitis (HP:0001082)2.00091532
105Glycosuria (HP:0003076)2.00062813
106Abnormality of urine glucose concentration (HP:0011016)2.00062813
107Respiratory failure (HP:0002878)1.99620857
108Abnormality of placental membranes (HP:0011409)1.99451212
109Amniotic constriction ring (HP:0009775)1.99451212
110Lethargy (HP:0001254)1.98232425
111Atrophy/Degeneration involving motor neurons (HP:0007373)1.96444746
112Cleft eyelid (HP:0000625)1.96392472
113Cervical subluxation (HP:0003308)1.95811529
114Pancytopenia (HP:0001876)1.95476070
115Nephronophthisis (HP:0000090)1.95422064
116Abnormal protein glycosylation (HP:0012346)1.95334142
117Abnormal glycosylation (HP:0012345)1.95334142
118Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.95334142
119Abnormal protein N-linked glycosylation (HP:0012347)1.95334142
120Trismus (HP:0000211)1.95216487
121Hypoplasia of the fovea (HP:0007750)1.94993141
122Aplasia/Hypoplasia of the fovea (HP:0008060)1.94993141
123Aplasia/Hypoplasia of the tongue (HP:0010295)1.94876596
124Embryonal renal neoplasm (HP:0011794)1.94493844
125Increased serum lactate (HP:0002151)1.93915374
126Respiratory difficulties (HP:0002880)1.92611415
127Abnormality of the duodenum (HP:0002246)1.92044953
128Vertebral compression fractures (HP:0002953)1.91799967
129Prolonged neonatal jaundice (HP:0006579)1.90653607
130Recurrent abscess formation (HP:0002722)1.89837019
131Facial cleft (HP:0002006)1.89727088
132Renal cortical cysts (HP:0000803)1.89692496
133Pancreatic islet-cell hyperplasia (HP:0004510)1.89634649
134Cellular immunodeficiency (HP:0005374)1.89287762
135Increased intramyocellular lipid droplets (HP:0012240)1.88695724
136Nephroblastoma (Wilms tumor) (HP:0002667)1.87923858
137Amaurosis fugax (HP:0100576)1.86696900
138Abnormality of endocrine pancreas physiology (HP:0012093)1.86580670
139Abnormality of the pancreatic islet cells (HP:0006476)1.86580670
140Hyperglycinuria (HP:0003108)1.85747919
141Bifid tongue (HP:0010297)1.85716239
142Congenital primary aphakia (HP:0007707)1.84639157
143Sparse eyelashes (HP:0000653)1.84344969
144Premature ovarian failure (HP:0008209)1.84096934
145Abnormal rod and cone electroretinograms (HP:0008323)1.83959469
146Abnormal spermatogenesis (HP:0008669)1.83879071
147Biliary tract neoplasm (HP:0100574)1.82613473
148Sloping forehead (HP:0000340)1.82409366
149Neoplasm of the colon (HP:0100273)1.82048631
1503-Methylglutaconic aciduria (HP:0003535)1.81806630
151Abnormality of the fovea (HP:0000493)1.81543521
152Vaginal fistula (HP:0004320)1.81278841
153Abnormality of glycolysis (HP:0004366)1.79545178
154Increased serum pyruvate (HP:0003542)1.79545178
155Aplasia/Hypoplasia of the sternum (HP:0006714)1.79476250
156Sensory axonal neuropathy (HP:0003390)1.79027886
157Microvesicular hepatic steatosis (HP:0001414)1.77496457
158Short thumb (HP:0009778)1.77392189
159Muscle fibrillation (HP:0010546)1.75363721
160Glossoptosis (HP:0000162)1.74366657
161Pulmonary fibrosis (HP:0002206)1.73937211
162Neoplasm of the pancreas (HP:0002894)1.73678797
163Hypoplasia of the capital femoral epiphysis (HP:0003090)1.72602863
164Spinal muscular atrophy (HP:0007269)1.71570630
165Intestinal fistula (HP:0100819)1.71013836
166Abnormality of the renal collecting system (HP:0004742)1.70635373
167Petechiae (HP:0000967)1.69650481
168Lymphoma (HP:0002665)1.69544221
169Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003)1.69473709
170Absent epiphyses (HP:0010577)1.69473709
171Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688)1.67415248
172Stenosis of the external auditory canal (HP:0000402)1.67347411
173Aplasia/Hypoplasia involving the musculature (HP:0001460)1.66741081

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB14.40071145
2VRK23.67119678
3EIF2AK13.62208435
4WEE13.47968728
5FRK2.69842457
6TRIM282.65727861
7PLK42.65626371
8TESK12.33524311
9PBK2.30081141
10BRSK22.26712567
11SRPK12.25487815
12ACVR1B2.22975465
13TESK22.22587045
14TSSK62.21748602
15STK162.19949048
16PIM22.19374090
17EIF2AK32.15931666
18WNK32.14756954
19CDC72.09835103
20STK38L1.97031080
21NEK11.85480101
22TNIK1.84837503
23MKNK11.83786987
24MUSK1.80898995
25VRK11.74267454
26NME21.69771829
27PLK11.64176079
28ZAK1.63387897
29TTK1.62466582
30ERBB31.53763159
31AKT31.53015971
32PLK31.51784479
33BRSK11.50434649
34RPS6KA41.48904498
35IRAK31.44651031
36MAP3K121.37853465
37STK241.37302060
38MAP4K21.36461394
39OXSR11.33889222
40LIMK11.32905566
41ATR1.28948883
42EIF2AK21.24064025
43SIK31.17607634
44STK391.16908442
45BRAF1.16546805
46MST41.13137993
47BCKDK1.13117070
48CDK71.13072625
49AURKB1.11454111
50EPHA21.11395520
51PAK41.08593701
52CHEK21.06984623
53MKNK21.06710944
54AURKA1.05903846
55NEK21.03198931
56TAF11.02003011
57ARAF1.01304304
58NUAK10.98857021
59CDK80.94857224
60PASK0.93431035
61TGFBR10.93130244
62IRAK40.92035267
63CCNB10.89328699
64BMPR20.89244174
65PIM10.87453384
66DYRK30.86139499
67BCR0.86008723
68YES10.82984190
69PLK20.80018186
70STK40.79739052
71CSNK1G10.79413374
72RPS6KB20.78521816
73TLK10.78266577
74MAP3K80.78025913
75TXK0.77557849
76KDR0.76637669
77TAOK20.75189349
78PAK10.75157623
79NME10.71187190
80DYRK20.70809736
81CSNK2A10.70342823
82IKBKB0.70124667
83STK30.69745826
84MYLK0.66723181
85MAP3K40.64894473
86NEK90.62607155
87FGFR20.61654888
88PAK30.61633933
89CSNK1G20.61593095
90CHEK10.60926840
91STK100.60318795
92CSNK1G30.60154391
93PRKCE0.59277669
94TIE10.57573518
95CDK40.56238327
96PDK20.55197830
97MAP3K110.54709715
98ADRBK20.53709009
99DAPK10.51746024
100INSRR0.50918599
101MAP3K140.48946709
102NEK60.48406872
103ATM0.48302588
104CHUK0.48226751
105PRKG20.48146391
106CASK0.48097686
107CSNK2A20.47777328
108JAK30.47190581
109PRKCI0.46521351
110FER0.46245749
111MAP3K30.45112934
112RPS6KA50.44660276
113BMPR1B0.43715018
114CDK20.40699578
115FGFR10.40358681
116ERBB40.39297368
117RAF10.39201306
118PRKCG0.36353581
119PINK10.36311023
120NLK0.36163242
121GRK10.36033472
122OBSCN0.35894666
123MAPK130.35101120
124ILK0.35059350
125CSF1R0.34211786
126CSNK1A1L0.33529555
127LYN0.33503890
128MAPKAPK30.32682364
129TEC0.32294601
130EGFR0.32287538
131PRKACB0.28138532
132MELK0.27511711
133CAMK2D0.27272203
134CAMK2A0.26899450
135CDK30.25717266
136MINK10.25613318
137IGF1R0.21821567
138FLT30.20505405
139CDK90.20384943

Predicted pathways (KEGG)

RankGene SetZ-score
1Proteasome_Homo sapiens_hsa030504.56514945
2DNA replication_Homo sapiens_hsa030304.49147428
3Mismatch repair_Homo sapiens_hsa034304.05962352
4Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030083.34307542
5RNA polymerase_Homo sapiens_hsa030203.25772850
6Homologous recombination_Homo sapiens_hsa034403.03209411
7Base excision repair_Homo sapiens_hsa034102.86144713
8Spliceosome_Homo sapiens_hsa030402.79183210
9Ribosome_Homo sapiens_hsa030102.63696079
10Nucleotide excision repair_Homo sapiens_hsa034202.59945443
11RNA transport_Homo sapiens_hsa030132.59102249
12One carbon pool by folate_Homo sapiens_hsa006702.49386224
13Pyrimidine metabolism_Homo sapiens_hsa002402.37477040
14Cell cycle_Homo sapiens_hsa041102.28208253
15Propanoate metabolism_Homo sapiens_hsa006402.24283857
16Non-homologous end-joining_Homo sapiens_hsa034502.09067632
17Fanconi anemia pathway_Homo sapiens_hsa034602.08479714
18Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.99823491
19Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.97326915
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.96223998
21Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.94262818
22Basal transcription factors_Homo sapiens_hsa030221.90141222
23Sulfur metabolism_Homo sapiens_hsa009201.88300415
24RNA degradation_Homo sapiens_hsa030181.73405927
25Fatty acid elongation_Homo sapiens_hsa000621.72468029
26Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.61981694
27Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.60136089
28Protein export_Homo sapiens_hsa030601.41458497
29Steroid biosynthesis_Homo sapiens_hsa001001.41340282
30Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.36497045
31Purine metabolism_Homo sapiens_hsa002301.34184263
32Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.34117205
33p53 signaling pathway_Homo sapiens_hsa041151.33731403
34Butanoate metabolism_Homo sapiens_hsa006501.31674053
35Pyruvate metabolism_Homo sapiens_hsa006201.30863667
36Epstein-Barr virus infection_Homo sapiens_hsa051691.26556601
37Legionellosis_Homo sapiens_hsa051341.22055526
38Pathogenic Escherichia coli infection_Homo sapiens_hsa051301.19215780
39Maturity onset diabetes of the young_Homo sapiens_hsa049501.18448291
40Vitamin B6 metabolism_Homo sapiens_hsa007501.18214644
41Tryptophan metabolism_Homo sapiens_hsa003801.13192344
42mRNA surveillance pathway_Homo sapiens_hsa030151.12352550
43Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.07750425
44Peroxisome_Homo sapiens_hsa041461.03582961
45Huntingtons disease_Homo sapiens_hsa050161.02500395
46Primary bile acid biosynthesis_Homo sapiens_hsa001201.01566725
47Caffeine metabolism_Homo sapiens_hsa002320.99464990
48Parkinsons disease_Homo sapiens_hsa050120.95062310
49Fructose and mannose metabolism_Homo sapiens_hsa000510.94049680
50Antigen processing and presentation_Homo sapiens_hsa046120.92518537
51Oxidative phosphorylation_Homo sapiens_hsa001900.91999646
52Glutathione metabolism_Homo sapiens_hsa004800.91311049
53Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.88718812
54Herpes simplex infection_Homo sapiens_hsa051680.86711159
55Phototransduction_Homo sapiens_hsa047440.84833431
56Shigellosis_Homo sapiens_hsa051310.79773847
57Folate biosynthesis_Homo sapiens_hsa007900.77989671
58Ether lipid metabolism_Homo sapiens_hsa005650.75701120
59Cardiac muscle contraction_Homo sapiens_hsa042600.74886044
60Pentose and glucuronate interconversions_Homo sapiens_hsa000400.74268556
61Graft-versus-host disease_Homo sapiens_hsa053320.72635469
62Nitrogen metabolism_Homo sapiens_hsa009100.70780162
63Arachidonic acid metabolism_Homo sapiens_hsa005900.70686436
64Fatty acid degradation_Homo sapiens_hsa000710.68649071
65Pentose phosphate pathway_Homo sapiens_hsa000300.68145323
66Allograft rejection_Homo sapiens_hsa053300.67931286
67Fatty acid metabolism_Homo sapiens_hsa012120.65743127
68Galactose metabolism_Homo sapiens_hsa000520.65661645
69Viral carcinogenesis_Homo sapiens_hsa052030.65491552
70Biosynthesis of amino acids_Homo sapiens_hsa012300.65326760
71Collecting duct acid secretion_Homo sapiens_hsa049660.63161475
72Other glycan degradation_Homo sapiens_hsa005110.62455713
73Drug metabolism - other enzymes_Homo sapiens_hsa009830.61214766
74Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.60666943
75Cysteine and methionine metabolism_Homo sapiens_hsa002700.58592262
76Apoptosis_Homo sapiens_hsa042100.54700370
77Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.54472705
78Glycosaminoglycan degradation_Homo sapiens_hsa005310.54274947
79HTLV-I infection_Homo sapiens_hsa051660.52860883
80NF-kappa B signaling pathway_Homo sapiens_hsa040640.52319073
81Selenocompound metabolism_Homo sapiens_hsa004500.52033668
82Oocyte meiosis_Homo sapiens_hsa041140.50688047
83TGF-beta signaling pathway_Homo sapiens_hsa043500.50562184
84Phagosome_Homo sapiens_hsa041450.50400183
85Linoleic acid metabolism_Homo sapiens_hsa005910.49822239
86Vitamin digestion and absorption_Homo sapiens_hsa049770.49552754
87beta-Alanine metabolism_Homo sapiens_hsa004100.48573099
88Circadian rhythm_Homo sapiens_hsa047100.48286605
89Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.48047134
90Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.47921133
91Chemical carcinogenesis_Homo sapiens_hsa052040.47753526
92Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.47371570
93Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.47230459
94Retinol metabolism_Homo sapiens_hsa008300.45761218
95Carbon metabolism_Homo sapiens_hsa012000.45688868
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.44809261
97Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.42033711
98Systemic lupus erythematosus_Homo sapiens_hsa053220.41782155
99SNARE interactions in vesicular transport_Homo sapiens_hsa041300.41470061
100Measles_Homo sapiens_hsa051620.41274505
101Regulation of autophagy_Homo sapiens_hsa041400.41192743
102Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.39566826
103Intestinal immune network for IgA production_Homo sapiens_hsa046720.39467641
104Hippo signaling pathway_Homo sapiens_hsa043900.39072760
105NOD-like receptor signaling pathway_Homo sapiens_hsa046210.38821459
106Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.38597465
107Leishmaniasis_Homo sapiens_hsa051400.38218625
108Thyroid cancer_Homo sapiens_hsa052160.37675927
109Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.37390563
110Autoimmune thyroid disease_Homo sapiens_hsa053200.37177626
111Rheumatoid arthritis_Homo sapiens_hsa053230.35305371
112Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049320.34683494
113Asthma_Homo sapiens_hsa053100.34426381
114Malaria_Homo sapiens_hsa051440.34244351
115Influenza A_Homo sapiens_hsa051640.33805913
116Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.32989048
1172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012100.31375290
118RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.31152347
119Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.30039167
120Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.29858818
121Metabolic pathways_Homo sapiens_hsa011000.28922750
122Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.28358382
123Alzheimers disease_Homo sapiens_hsa050100.27869753
124N-Glycan biosynthesis_Homo sapiens_hsa005100.27696946
125Lysosome_Homo sapiens_hsa041420.27630079
126Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.27177366
127Hematopoietic cell lineage_Homo sapiens_hsa046400.26827969
128Arginine and proline metabolism_Homo sapiens_hsa003300.26722198
129alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.26504141
130Pertussis_Homo sapiens_hsa051330.25822723
131Taste transduction_Homo sapiens_hsa047420.25741287
132Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.25731346
133Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.25657499
134Type I diabetes mellitus_Homo sapiens_hsa049400.25334665
135Olfactory transduction_Homo sapiens_hsa047400.24946512
136Hepatitis B_Homo sapiens_hsa051610.23326527
137Vibrio cholerae infection_Homo sapiens_hsa051100.23283978
138Small cell lung cancer_Homo sapiens_hsa052220.23150955
139Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.21633884
140Transcriptional misregulation in cancer_Homo sapiens_hsa052020.21617029
141Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.20161417
142Adherens junction_Homo sapiens_hsa045200.19325947
143Fat digestion and absorption_Homo sapiens_hsa049750.18736749
144Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.17776800

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