

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | attachment of spindle microtubules to kinetochore (GO:0008608) | 5.52992928 |
| 2 | cullin deneddylation (GO:0010388) | 4.58558318 |
| 3 | establishment of integrated proviral latency (GO:0075713) | 4.43214719 |
| 4 | DNA strand elongation involved in DNA replication (GO:0006271) | 4.42955859 |
| 5 | protein deneddylation (GO:0000338) | 4.42390204 |
| 6 | telomere maintenance via semi-conservative replication (GO:0032201) | 4.40960200 |
| 7 | protein neddylation (GO:0045116) | 4.40749782 |
| 8 | purine nucleobase biosynthetic process (GO:0009113) | 4.36830404 |
| 9 | DNA strand elongation (GO:0022616) | 4.22757218 |
| 10 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 4.22017684 |
| 11 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 4.22017684 |
| 12 | regulation of translation, ncRNA-mediated (GO:0045974) | 4.22017684 |
| 13 | nucleobase biosynthetic process (GO:0046112) | 4.19049972 |
| 14 | proteasome assembly (GO:0043248) | 4.17619565 |
| 15 | telomere maintenance via recombination (GO:0000722) | 4.15249835 |
| 16 | DNA replication checkpoint (GO:0000076) | 4.10210539 |
| 17 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.08662225 |
| 18 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.00726111 |
| 19 | DNA deamination (GO:0045006) | 4.00446053 |
| 20 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.99972021 |
| 21 | respiratory chain complex IV assembly (GO:0008535) | 3.93134603 |
| 22 | DNA replication initiation (GO:0006270) | 3.91619253 |
| 23 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.89971959 |
| 24 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.89619133 |
| 25 | mitotic metaphase plate congression (GO:0007080) | 3.85974650 |
| 26 | formation of translation preinitiation complex (GO:0001731) | 3.85388584 |
| 27 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 3.84168635 |
| 28 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.83669857 |
| 29 | mitotic recombination (GO:0006312) | 3.83089419 |
| 30 | nuclear pore organization (GO:0006999) | 3.76750971 |
| 31 | IMP biosynthetic process (GO:0006188) | 3.71587627 |
| 32 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.69754088 |
| 33 | ribosomal small subunit assembly (GO:0000028) | 3.68322867 |
| 34 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.66114613 |
| 35 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.66114613 |
| 36 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.66114613 |
| 37 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.65630505 |
| 38 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.65630505 |
| 39 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.64381656 |
| 40 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.64381656 |
| 41 | negative regulation of ligase activity (GO:0051352) | 3.63532548 |
| 42 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.63532548 |
| 43 | telomere maintenance via telomere lengthening (GO:0010833) | 3.62364184 |
| 44 | nucleotide-excision repair, DNA gap filling (GO:0006297) | 3.62163162 |
| 45 | metaphase plate congression (GO:0051310) | 3.59973047 |
| 46 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.56848906 |
| 47 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.56848906 |
| 48 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.54656082 |
| 49 | folic acid-containing compound biosynthetic process (GO:0009396) | 3.53309974 |
| 50 | pteridine-containing compound biosynthetic process (GO:0042559) | 3.53026414 |
| 51 | heart process (GO:0003015) | 3.52244785 |
| 52 | heart contraction (GO:0060047) | 3.52244785 |
| 53 | CENP-A containing nucleosome assembly (GO:0034080) | 3.52119039 |
| 54 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.49916752 |
| 55 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.49209506 |
| 56 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.48069302 |
| 57 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.47703218 |
| 58 | ribosome biogenesis (GO:0042254) | 3.46419677 |
| 59 | establishment of viral latency (GO:0019043) | 3.44026459 |
| 60 | cytochrome complex assembly (GO:0017004) | 3.42961817 |
| 61 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 3.41342156 |
| 62 | chromatin remodeling at centromere (GO:0031055) | 3.39687570 |
| 63 | lactate metabolic process (GO:0006089) | 3.39195824 |
| 64 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.38713389 |
| 65 | kinetochore organization (GO:0051383) | 3.36484603 |
| 66 | establishment of chromosome localization (GO:0051303) | 3.36252710 |
| 67 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.34927976 |
| 68 | positive regulation of ligase activity (GO:0051351) | 3.32429243 |
| 69 | histone exchange (GO:0043486) | 3.32295379 |
| 70 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.31940205 |
| 71 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.29572601 |
| 72 | ATP synthesis coupled proton transport (GO:0015986) | 3.29572601 |
| 73 | pseudouridine synthesis (GO:0001522) | 3.29197196 |
| 74 | cell cycle G1/S phase transition (GO:0044843) | 3.28641729 |
| 75 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.28641729 |
| 76 | regulation of double-strand break repair via homologous recombination (GO:0010569) | 3.27736607 |
| 77 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.26534010 |
| 78 | kinetochore assembly (GO:0051382) | 3.25595702 |
| 79 | histone mRNA metabolic process (GO:0008334) | 3.25487419 |
| 80 | microtubule cytoskeleton organization involved in mitosis (GO:1902850) | 3.25233588 |
| 81 | rRNA modification (GO:0000154) | 3.23204049 |
| 82 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.20876480 |
| 83 | 7-methylguanosine mRNA capping (GO:0006370) | 3.18712301 |
| 84 | protein complex biogenesis (GO:0070271) | 3.17993065 |
| 85 | somatic recombination of immunoglobulin genes involved in immune response (GO:0002204) | 3.17264024 |
| 86 | somatic diversification of immunoglobulins involved in immune response (GO:0002208) | 3.17264024 |
| 87 | isotype switching (GO:0045190) | 3.17264024 |
| 88 | spliceosomal snRNP assembly (GO:0000387) | 3.16116196 |
| 89 | regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083) | 3.15401393 |
| 90 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.13622465 |
| 91 | deoxyribonucleotide biosynthetic process (GO:0009263) | 3.12893343 |
| 92 | 7-methylguanosine RNA capping (GO:0009452) | 3.12302770 |
| 93 | RNA capping (GO:0036260) | 3.12302770 |
| 94 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 3.11141543 |
| 95 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 3.11141543 |
| 96 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.11004472 |
| 97 | positive regulation of cell cycle arrest (GO:0071158) | 3.10247914 |
| 98 | viral mRNA export from host cell nucleus (GO:0046784) | 3.09905895 |
| 99 | maturation of SSU-rRNA (GO:0030490) | 3.09237530 |
| 100 | sequestering of actin monomers (GO:0042989) | 3.09025412 |
| 101 | IMP metabolic process (GO:0046040) | 3.07751759 |
| 102 | DNA ligation (GO:0006266) | 3.07573510 |
| 103 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.07302567 |
| 104 | termination of RNA polymerase III transcription (GO:0006386) | 3.07302567 |
| 105 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.06669241 |
| 106 | telomere maintenance (GO:0000723) | 3.06109567 |
| 107 | telomere organization (GO:0032200) | 3.05948461 |
| 108 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.05698010 |
| 109 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.05698010 |
| 110 | DNA double-strand break processing (GO:0000729) | 3.04492565 |
| 111 | synapsis (GO:0007129) | 3.03094654 |
| 112 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.02443092 |
| 113 | mitotic nuclear envelope disassembly (GO:0007077) | 3.02342923 |
| 114 | meiotic chromosome segregation (GO:0045132) | 3.01981332 |
| 115 | transcription from RNA polymerase I promoter (GO:0006360) | 3.00860259 |
| 116 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.00768444 |
| 117 | resolution of meiotic recombination intermediates (GO:0000712) | 3.00730844 |
| 118 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.00669034 |
| 119 | maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005) | 3.00484307 |
| 120 | replication fork processing (GO:0031297) | 2.99992381 |
| 121 | chaperone-mediated protein transport (GO:0072321) | 2.99559990 |
| 122 | regulation of meiosis I (GO:0060631) | 2.96181736 |
| 123 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 2.95050370 |
| 124 | platelet dense granule organization (GO:0060155) | 2.95047989 |
| 125 | nucleobase-containing small molecule interconversion (GO:0015949) | 2.94845371 |
| 126 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.93236571 |
| 127 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.93236571 |
| 128 | protein localization to kinetochore (GO:0034501) | 2.92943004 |
| 129 | DNA replication-independent nucleosome assembly (GO:0006336) | 2.92154787 |
| 130 | DNA replication-independent nucleosome organization (GO:0034724) | 2.92154787 |
| 131 | DNA unwinding involved in DNA replication (GO:0006268) | 2.91128114 |
| 132 | regulation of ligase activity (GO:0051340) | 2.90401662 |
| 133 | ribosome assembly (GO:0042255) | 2.86712034 |
| 134 | response to X-ray (GO:0010165) | 2.86410413 |
| 135 | maturation of 5.8S rRNA (GO:0000460) | 2.85949679 |
| 136 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.85293096 |
| 137 | NADH dehydrogenase complex assembly (GO:0010257) | 2.85293096 |
| 138 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.85293096 |
| 139 | intra-S DNA damage checkpoint (GO:0031573) | 2.84512275 |
| 140 | respiratory electron transport chain (GO:0022904) | 2.83408875 |
| 141 | non-recombinational repair (GO:0000726) | 2.82962731 |
| 142 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.82962731 |
| 143 | DNA catabolic process, exonucleolytic (GO:0000738) | 2.82328901 |
| 144 | regulation of helicase activity (GO:0051095) | 2.81893947 |
| 145 | deoxyribose phosphate biosynthetic process (GO:0046385) | 2.81450573 |
| 146 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 2.81450573 |
| 147 | antigen processing and presentation of peptide antigen via MHC class I (GO:0002474) | 2.79964752 |
| 148 | regulation of DNA endoreduplication (GO:0032875) | 2.79292339 |
| 149 | negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class | 2.79147261 |
| 150 | rRNA processing (GO:0006364) | 2.79141854 |
| 151 | postreplication repair (GO:0006301) | 2.78739523 |
| 152 | electron transport chain (GO:0022900) | 2.78271593 |
| 153 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.78064937 |
| 154 | branched-chain amino acid catabolic process (GO:0009083) | 2.75873785 |
| 155 | spindle checkpoint (GO:0031577) | 2.70199260 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 7.66647032 |
| 2 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.12887376 |
| 3 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.73226418 |
| 4 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.40394277 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.35386652 |
| 6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.28077966 |
| 7 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.14341189 |
| 8 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 3.13591846 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.03984717 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.89638934 |
| 11 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.85700162 |
| 12 | * MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.85310577 |
| 13 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.83936263 |
| 14 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.71546016 |
| 15 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.70297488 |
| 16 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.63207218 |
| 17 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.52689420 |
| 18 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.46313301 |
| 19 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.40775368 |
| 20 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.35881839 |
| 21 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.35804034 |
| 22 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.34522077 |
| 23 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.27389702 |
| 24 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.26554622 |
| 25 | VDR_22108803_ChIP-Seq_LS180_Human | 2.25499104 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 2.23558053 |
| 27 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.22284312 |
| 28 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.17804867 |
| 29 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.16623956 |
| 30 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.07902462 |
| 31 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.07190551 |
| 32 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.03952329 |
| 33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.02737012 |
| 34 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 2.02034046 |
| 35 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.97222013 |
| 36 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.96650893 |
| 37 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.93293489 |
| 38 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.89260595 |
| 39 | FUS_26573619_Chip-Seq_HEK293_Human | 1.88369136 |
| 40 | P300_19829295_ChIP-Seq_ESCs_Human | 1.86306422 |
| 41 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.84853487 |
| 42 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.83194128 |
| 43 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.82972675 |
| 44 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.81776522 |
| 45 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.81453752 |
| 46 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.79820851 |
| 47 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.75405362 |
| 48 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.71646328 |
| 49 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.70401679 |
| 50 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.70361062 |
| 51 | * MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.69723077 |
| 52 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.68962910 |
| 53 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.67971363 |
| 54 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.67907377 |
| 55 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.64542201 |
| 56 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.62685313 |
| 57 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.60430873 |
| 58 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.58800170 |
| 59 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.56503748 |
| 60 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 1.54466155 |
| 61 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.54397809 |
| 62 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.54156943 |
| 63 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.51389783 |
| 64 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.50920891 |
| 65 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.50772350 |
| 66 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.50414558 |
| 67 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.49365886 |
| 68 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.49059396 |
| 69 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.48430502 |
| 70 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.45980726 |
| 71 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.45637155 |
| 72 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.45637155 |
| 73 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.45637155 |
| 74 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.44231000 |
| 75 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.37396692 |
| 76 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.37188032 |
| 77 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.37161698 |
| 78 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.36967464 |
| 79 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.36601029 |
| 80 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.36026654 |
| 81 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.35328822 |
| 82 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.29791171 |
| 83 | * AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.29675038 |
| 84 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.28460924 |
| 85 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.27745752 |
| 86 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.27690692 |
| 87 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.27638589 |
| 88 | * SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.26693633 |
| 89 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.25435324 |
| 90 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.24706371 |
| 91 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.24656428 |
| 92 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.24642154 |
| 93 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.23584232 |
| 94 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.22751258 |
| 95 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.21299550 |
| 96 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.21043452 |
| 97 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.19845658 |
| 98 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.19742242 |
| 99 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.19266000 |
| 100 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.19266000 |
| 101 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.19220290 |
| 102 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.18916232 |
| 103 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.15781457 |
| 104 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.15244768 |
| 105 | * OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.15120658 |
| 106 | SMAD1_18555785_ChIP-Seq_MESCs_Mouse | 1.14092709 |
| 107 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.13551742 |
| 108 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.11766516 |
| 109 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.10744295 |
| 110 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.09958332 |
| 111 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.09536739 |
| 112 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.09363583 |
| 113 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.08419356 |
| 114 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.08419356 |
| 115 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.07198292 |
| 116 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.05956672 |
| 117 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.05897333 |
| 118 | * MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.05886046 |
| 119 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.05769410 |
| 120 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.05074288 |
| 121 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.05050920 |
| 122 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.04634908 |
| 123 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.04233616 |
| 124 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.04062689 |
| 125 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 1.03992930 |
| 126 | NANOG_18358816_ChIP-ChIP_MESCs_Mouse | 1.03055543 |
| 127 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.02892699 |
| 128 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.02710958 |
| 129 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.02450471 |
| 130 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.01702937 |
| 131 | * SMAD4_21799915_ChIP-Seq_A2780_Human | 1.00713583 |
| 132 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.00492910 |
| 133 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.00106447 |
| 134 | KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 0.99588747 |
| 135 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.99349319 |
| 136 | * SPI1_23547873_ChIP-Seq_NB4_Human | 0.98999204 |
| 137 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.98848514 |
| 138 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 0.97896821 |
| 139 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.97498946 |
| 140 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 0.97031396 |
| 141 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.95856858 |
| 142 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.95200967 |
| 143 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.95121291 |
| 144 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 0.94517424 |
| 145 | KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.94437669 |
| 146 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.93492953 |
| 147 | * SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.91887164 |
| 148 | MYC_18940864_ChIP-ChIP_HL60_Human | 0.90032004 |
| 149 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.88868930 |
| 150 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.88182265 |
| 151 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.88127126 |
| 152 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.86199149 |
| 153 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 0.82556091 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 4.67309735 |
| 2 | MP0010094_abnormal_chromosome_stability | 3.96153331 |
| 3 | MP0004957_abnormal_blastocyst_morpholog | 3.90363511 |
| 4 | MP0008058_abnormal_DNA_repair | 3.57176597 |
| 5 | MP0003077_abnormal_cell_cycle | 3.45550967 |
| 6 | MP0008789_abnormal_olfactory_epithelium | 3.36434824 |
| 7 | MP0003111_abnormal_nucleus_morphology | 3.27821988 |
| 8 | MP0002102_abnormal_ear_morphology | 3.27408719 |
| 9 | MP0008007_abnormal_cellular_replicative | 3.21247974 |
| 10 | MP0008057_abnormal_DNA_replication | 3.09064780 |
| 11 | MP0008932_abnormal_embryonic_tissue | 2.66678534 |
| 12 | MP0001529_abnormal_vocalization | 2.66226916 |
| 13 | MP0006072_abnormal_retinal_apoptosis | 2.59555445 |
| 14 | MP0003806_abnormal_nucleotide_metabolis | 2.43252237 |
| 15 | MP0002837_dystrophic_cardiac_calcinosis | 2.34718612 |
| 16 | MP0003186_abnormal_redox_activity | 2.29840843 |
| 17 | MP0003195_calcinosis | 2.27881804 |
| 18 | MP0003123_paternal_imprinting | 2.27725815 |
| 19 | MP0003941_abnormal_skin_development | 2.25656673 |
| 20 | MP0003011_delayed_dark_adaptation | 2.25445281 |
| 21 | MP0005394_taste/olfaction_phenotype | 2.21485174 |
| 22 | MP0005499_abnormal_olfactory_system | 2.21485174 |
| 23 | MP0003786_premature_aging | 2.13994437 |
| 24 | MP0005084_abnormal_gallbladder_morpholo | 2.06442481 |
| 25 | MP0005253_abnormal_eye_physiology | 1.94933423 |
| 26 | MP0001485_abnormal_pinna_reflex | 1.91312947 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.76659093 |
| 28 | MP0009697_abnormal_copulation | 1.76328026 |
| 29 | MP0003718_maternal_effect | 1.76280987 |
| 30 | MP0006292_abnormal_olfactory_placode | 1.73003569 |
| 31 | MP0001730_embryonic_growth_arrest | 1.72019615 |
| 32 | MP0008877_abnormal_DNA_methylation | 1.71114037 |
| 33 | MP0000350_abnormal_cell_proliferation | 1.70827177 |
| 34 | MP0010030_abnormal_orbit_morphology | 1.68575071 |
| 35 | MP0001984_abnormal_olfaction | 1.64231681 |
| 36 | MP0002396_abnormal_hematopoietic_system | 1.59577110 |
| 37 | MP0002736_abnormal_nociception_after | 1.57619230 |
| 38 | MP0000569_abnormal_digit_pigmentation | 1.56583092 |
| 39 | MP0006036_abnormal_mitochondrial_physio | 1.55550622 |
| 40 | MP0000490_abnormal_crypts_of | 1.53061631 |
| 41 | MP0001835_abnormal_antigen_presentation | 1.49995985 |
| 42 | MP0004215_abnormal_myocardial_fiber | 1.48819614 |
| 43 | MP0005379_endocrine/exocrine_gland_phen | 1.48764033 |
| 44 | MP0010352_gastrointestinal_tract_polyps | 1.42960903 |
| 45 | MP0002090_abnormal_vision | 1.42855958 |
| 46 | MP0005551_abnormal_eye_electrophysiolog | 1.39666840 |
| 47 | MP0002751_abnormal_autonomic_nervous | 1.39511064 |
| 48 | MP0003121_genomic_imprinting | 1.38693737 |
| 49 | MP0005395_other_phenotype | 1.35444083 |
| 50 | MP0004084_abnormal_cardiac_muscle | 1.35391917 |
| 51 | MP0001764_abnormal_homeostasis | 1.30790419 |
| 52 | MP0000313_abnormal_cell_death | 1.30725873 |
| 53 | MP0001697_abnormal_embryo_size | 1.30407266 |
| 54 | MP0005332_abnormal_amino_acid | 1.30138573 |
| 55 | MP0000566_synostosis | 1.30129123 |
| 56 | MP0003950_abnormal_plasma_membrane | 1.29846146 |
| 57 | MP0003880_abnormal_central_pattern | 1.29160654 |
| 58 | MP0002254_reproductive_system_inflammat | 1.27377014 |
| 59 | MP0002148_abnormal_hypersensitivity_rea | 1.25548985 |
| 60 | MP0001672_abnormal_embryogenesis/_devel | 1.24561757 |
| 61 | MP0005380_embryogenesis_phenotype | 1.24561757 |
| 62 | MP0004145_abnormal_muscle_electrophysio | 1.22369672 |
| 63 | MP0002132_abnormal_respiratory_system | 1.21553193 |
| 64 | MP0002938_white_spotting | 1.20910809 |
| 65 | MP0008872_abnormal_physiological_respon | 1.20284844 |
| 66 | MP0002019_abnormal_tumor_incidence | 1.17394136 |
| 67 | MP0002233_abnormal_nose_morphology | 1.17203442 |
| 68 | MP0003890_abnormal_embryonic-extraembry | 1.16935481 |
| 69 | MP0006276_abnormal_autonomic_nervous | 1.12562324 |
| 70 | MP0000015_abnormal_ear_pigmentation | 1.11987977 |
| 71 | MP0009333_abnormal_splenocyte_physiolog | 1.11756490 |
| 72 | MP0001293_anophthalmia | 1.11163828 |
| 73 | MP0004808_abnormal_hematopoietic_stem | 1.11086900 |
| 74 | MP0000427_abnormal_hair_cycle | 1.10828538 |
| 75 | MP0003984_embryonic_growth_retardation | 1.10627478 |
| 76 | MP0005058_abnormal_lysosome_morphology | 1.09807954 |
| 77 | MP0004133_heterotaxia | 1.09773458 |
| 78 | MP0006035_abnormal_mitochondrial_morpho | 1.09641908 |
| 79 | MP0001853_heart_inflammation | 1.08952940 |
| 80 | MP0010307_abnormal_tumor_latency | 1.07930701 |
| 81 | MP0002080_prenatal_lethality | 1.07923059 |
| 82 | MP0004147_increased_porphyrin_level | 1.07238199 |
| 83 | MP0002638_abnormal_pupillary_reflex | 1.06242481 |
| 84 | MP0001929_abnormal_gametogenesis | 1.05990073 |
| 85 | MP0002088_abnormal_embryonic_growth/wei | 1.05732293 |
| 86 | MP0005503_abnormal_tendon_morphology | 1.03859009 |
| 87 | MP0000653_abnormal_sex_gland | 1.02914986 |
| 88 | MP0001119_abnormal_female_reproductive | 1.01906557 |
| 89 | MP0000343_altered_response_to | 1.01605472 |
| 90 | MP0009785_altered_susceptibility_to | 1.00268198 |
| 91 | MP0002210_abnormal_sex_determination | 0.99319490 |
| 92 | MP0005671_abnormal_response_to | 0.98846983 |
| 93 | MP0002085_abnormal_embryonic_tissue | 0.98835402 |
| 94 | MP0003448_altered_tumor_morphology | 0.98578848 |
| 95 | MP0005389_reproductive_system_phenotype | 0.96880971 |
| 96 | MP0003566_abnormal_cell_adhesion | 0.96128658 |
| 97 | MP0003315_abnormal_perineum_morphology | 0.95421782 |
| 98 | MP0008260_abnormal_autophagy | 0.95410605 |
| 99 | MP0002160_abnormal_reproductive_system | 0.94754877 |
| 100 | MP0002277_abnormal_respiratory_mucosa | 0.94100451 |
| 101 | MP0005023_abnormal_wound_healing | 0.93338260 |
| 102 | MP0005075_abnormal_melanosome_morpholog | 0.93226967 |
| 103 | MP0000858_altered_metastatic_potential | 0.92901450 |
| 104 | MP0005408_hypopigmentation | 0.92095278 |
| 105 | MP0008438_abnormal_cutaneous_collagen | 0.91912885 |
| 106 | MP0002086_abnormal_extraembryonic_tissu | 0.90212827 |
| 107 | MP0000358_abnormal_cell_content/ | 0.89791057 |
| 108 | MP0003567_abnormal_fetal_cardiomyocyte | 0.89765020 |
| 109 | MP0008875_abnormal_xenobiotic_pharmacok | 0.88152843 |
| 110 | MP0003136_yellow_coat_color | 0.87825482 |
| 111 | MP0001968_abnormal_touch/_nociception | 0.87560544 |
| 112 | MP0009379_abnormal_foot_pigmentation | 0.87415136 |
| 113 | MP0006082_CNS_inflammation | 0.86238523 |
| 114 | MP0002084_abnormal_developmental_patter | 0.86077250 |
| 115 | MP0005174_abnormal_tail_pigmentation | 0.85739336 |
| 116 | MP0004197_abnormal_fetal_growth/weight/ | 0.85572204 |
| 117 | MP0005391_vision/eye_phenotype | 0.85082543 |
| 118 | MP0001542_abnormal_bone_strength | 0.84715154 |
| 119 | MP0000049_abnormal_middle_ear | 0.84322226 |
| 120 | MP0010386_abnormal_urinary_bladder | 0.83619866 |
| 121 | MP0003763_abnormal_thymus_physiology | 0.83353970 |
| 122 | MP0003787_abnormal_imprinting | 0.82946366 |
| 123 | MP0002653_abnormal_ependyma_morphology | 0.82684732 |
| 124 | MP0005636_abnormal_mineral_homeostasis | 0.81703703 |
| 125 | MP0000689_abnormal_spleen_morphology | 0.81648676 |
| 126 | MP0005397_hematopoietic_system_phenotyp | 0.81578664 |
| 127 | MP0001545_abnormal_hematopoietic_system | 0.81578664 |
| 128 | MP0002163_abnormal_gland_morphology | 0.80807754 |
| 129 | MP0000749_muscle_degeneration | 0.80193844 |
| 130 | MP0001145_abnormal_male_reproductive | 0.80153978 |
| 131 | MP0005085_abnormal_gallbladder_physiolo | 0.79729719 |
| 132 | MP0002722_abnormal_immune_system | 0.79105862 |
| 133 | MP0002452_abnormal_antigen_presenting | 0.77264578 |
| 134 | MP0002398_abnormal_bone_marrow | 0.77143954 |
| 135 | MP0000516_abnormal_urinary_system | 0.75320676 |
| 136 | MP0005367_renal/urinary_system_phenotyp | 0.75320676 |
| 137 | MP0002405_respiratory_system_inflammati | 0.75317403 |
| 138 | MP0006054_spinal_hemorrhage | 0.74207424 |
| 139 | MP0001919_abnormal_reproductive_system | 0.73515783 |
| 140 | MP0002429_abnormal_blood_cell | 0.72277812 |
| 141 | MP0009780_abnormal_chondrocyte_physiolo | 0.71993952 |
| 142 | MP0000647_abnormal_sebaceous_gland | 0.71859367 |
| 143 | MP0005384_cellular_phenotype | 0.71825412 |
| 144 | MP0004782_abnormal_surfactant_physiolog | 0.71496302 |
| 145 | MP0001324_abnormal_eye_pigmentation | 0.71431201 |
| 146 | MP0000631_abnormal_neuroendocrine_gland | 0.69091690 |
| 147 | MP0002127_abnormal_cardiovascular_syste | 0.68832222 |
| 148 | MP0003937_abnormal_limbs/digits/tail_de | 0.68741949 |
| 149 | MP0003436_decreased_susceptibility_to | 0.68373120 |
| 150 | MP0003943_abnormal_hepatobiliary_system | 0.68263078 |
| 151 | MP0008995_early_reproductive_senescence | 0.68200148 |
| 152 | MP0002111_abnormal_tail_morphology | 0.68009641 |
| 153 | MP0001186_pigmentation_phenotype | 0.67861877 |
| 154 | MP0003221_abnormal_cardiomyocyte_apopto | 0.67056695 |
| 155 | MP0002095_abnormal_skin_pigmentation | 0.65988634 |
| 156 | MP0005410_abnormal_fertilization | 0.65561956 |
| 157 | MP0001819_abnormal_immune_cell | 0.65136094 |
| 158 | MP0005646_abnormal_pituitary_gland | 0.64965653 |
| 159 | MP0003698_abnormal_male_reproductive | 0.63774309 |
| 160 | MP0005220_abnormal_exocrine_pancreas | 0.63248580 |
| 161 | MP0008775_abnormal_heart_ventricle | 0.60546537 |
| 162 | MP0001177_atelectasis | 0.60490975 |
| 163 | MP0003122_maternal_imprinting | 0.59702764 |
| 164 | MP0001188_hyperpigmentation | 0.58309418 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Birth length less than 3rd percentile (HP:0003561) | 4.52337512 |
| 2 | Abnormality of the anterior horn cell (HP:0006802) | 3.85934653 |
| 3 | Degeneration of anterior horn cells (HP:0002398) | 3.85934653 |
| 4 | Chromsome breakage (HP:0040012) | 3.76254123 |
| 5 | Methylmalonic acidemia (HP:0002912) | 3.74012542 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 3.71998861 |
| 7 | Aplastic anemia (HP:0001915) | 3.71303006 |
| 8 | Acute necrotizing encephalopathy (HP:0006965) | 3.70606369 |
| 9 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 3.52392725 |
| 10 | Agnosia (HP:0010524) | 3.44554819 |
| 11 | Acute encephalopathy (HP:0006846) | 3.42332953 |
| 12 | Lipid accumulation in hepatocytes (HP:0006561) | 3.39377432 |
| 13 | Progressive macrocephaly (HP:0004481) | 3.38680636 |
| 14 | Breast hypoplasia (HP:0003187) | 3.37257371 |
| 15 | Mitochondrial inheritance (HP:0001427) | 3.33528249 |
| 16 | Increased CSF lactate (HP:0002490) | 3.28743250 |
| 17 | Type I transferrin isoform profile (HP:0003642) | 3.22429310 |
| 18 | Oral leukoplakia (HP:0002745) | 3.20839800 |
| 19 | Carpal bone hypoplasia (HP:0001498) | 3.13948446 |
| 20 | Meckel diverticulum (HP:0002245) | 3.13376663 |
| 21 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.09577192 |
| 22 | Cerebral hypomyelination (HP:0006808) | 3.08184379 |
| 23 | Abnormality of the ileum (HP:0001549) | 3.03778046 |
| 24 | Patellar aplasia (HP:0006443) | 3.03192465 |
| 25 | Abnormality of the preputium (HP:0100587) | 2.96960181 |
| 26 | Renal Fanconi syndrome (HP:0001994) | 2.93929537 |
| 27 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.91836525 |
| 28 | Rough bone trabeculation (HP:0100670) | 2.89391194 |
| 29 | Methylmalonic aciduria (HP:0012120) | 2.88225899 |
| 30 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.87869908 |
| 31 | Abnormality of methionine metabolism (HP:0010901) | 2.87236091 |
| 32 | Abnormality of chromosome stability (HP:0003220) | 2.84742729 |
| 33 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.83054683 |
| 34 | Premature graying of hair (HP:0002216) | 2.74113719 |
| 35 | Pancreatic cysts (HP:0001737) | 2.73677296 |
| 36 | Colon cancer (HP:0003003) | 2.71400671 |
| 37 | Selective tooth agenesis (HP:0001592) | 2.70928421 |
| 38 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 2.70797697 |
| 39 | Absent radius (HP:0003974) | 2.69219992 |
| 40 | Hepatic necrosis (HP:0002605) | 2.68272801 |
| 41 | Cerebral edema (HP:0002181) | 2.67686271 |
| 42 | Reticulocytopenia (HP:0001896) | 2.64142710 |
| 43 | Pancreatic fibrosis (HP:0100732) | 2.63196457 |
| 44 | Abnormality of the labia minora (HP:0012880) | 2.62828671 |
| 45 | Hepatocellular necrosis (HP:0001404) | 2.61654163 |
| 46 | Poor head control (HP:0002421) | 2.58625906 |
| 47 | Irregular epiphyses (HP:0010582) | 2.58070807 |
| 48 | Neoplasm of the adrenal gland (HP:0100631) | 2.51575523 |
| 49 | Hyperglycinemia (HP:0002154) | 2.50345809 |
| 50 | Hypoglycemic coma (HP:0001325) | 2.49982671 |
| 51 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.49604150 |
| 52 | Abnormal lung lobation (HP:0002101) | 2.49496759 |
| 53 | Absent thumb (HP:0009777) | 2.48906287 |
| 54 | Supernumerary spleens (HP:0009799) | 2.44765644 |
| 55 | Absent forearm bone (HP:0003953) | 2.42974067 |
| 56 | Aplasia involving forearm bones (HP:0009822) | 2.42974067 |
| 57 | Bone marrow hypocellularity (HP:0005528) | 2.42826718 |
| 58 | Abnormal trabecular bone morphology (HP:0100671) | 2.41676729 |
| 59 | Small intestinal stenosis (HP:0012848) | 2.39636308 |
| 60 | Duodenal stenosis (HP:0100867) | 2.39636308 |
| 61 | Abnormality of vitamin B metabolism (HP:0004340) | 2.39621415 |
| 62 | Exertional dyspnea (HP:0002875) | 2.37334966 |
| 63 | Volvulus (HP:0002580) | 2.35877620 |
| 64 | True hermaphroditism (HP:0010459) | 2.35193345 |
| 65 | Medulloblastoma (HP:0002885) | 2.32221894 |
| 66 | Microretrognathia (HP:0000308) | 2.31159223 |
| 67 | Abnormality of serum amino acid levels (HP:0003112) | 2.28122380 |
| 68 | 11 pairs of ribs (HP:0000878) | 2.27325854 |
| 69 | Reduced antithrombin III activity (HP:0001976) | 2.25538731 |
| 70 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.24574797 |
| 71 | Intestinal atresia (HP:0011100) | 2.23467933 |
| 72 | Type 2 muscle fiber atrophy (HP:0003554) | 2.23250490 |
| 73 | Rectovaginal fistula (HP:0000143) | 2.22892139 |
| 74 | Rectal fistula (HP:0100590) | 2.22892139 |
| 75 | Myelodysplasia (HP:0002863) | 2.21720814 |
| 76 | Palpitations (HP:0001962) | 2.17783634 |
| 77 | Medial flaring of the eyebrow (HP:0010747) | 2.17603163 |
| 78 | Tongue fasciculations (HP:0001308) | 2.16884069 |
| 79 | Lactic acidosis (HP:0003128) | 2.16736805 |
| 80 | Rhabdomyosarcoma (HP:0002859) | 2.15172548 |
| 81 | Ependymoma (HP:0002888) | 2.13628982 |
| 82 | Aplasia/Hypoplasia involving the carpal bones (HP:0006502) | 2.13268320 |
| 83 | Hypoglycemic seizures (HP:0002173) | 2.12817854 |
| 84 | Abnormality of glycine metabolism (HP:0010895) | 2.12645155 |
| 85 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.12645155 |
| 86 | Neoplasm of the adrenal cortex (HP:0100641) | 2.12576544 |
| 87 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 2.10623351 |
| 88 | Abnormality of midbrain morphology (HP:0002418) | 2.10455116 |
| 89 | Molar tooth sign on MRI (HP:0002419) | 2.10455116 |
| 90 | Abolished electroretinogram (ERG) (HP:0000550) | 2.08171968 |
| 91 | Hypothermia (HP:0002045) | 2.07470445 |
| 92 | Abnormal biliary tract physiology (HP:0012439) | 2.05120101 |
| 93 | Bile duct proliferation (HP:0001408) | 2.05120101 |
| 94 | Glioma (HP:0009733) | 2.05045997 |
| 95 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.04936674 |
| 96 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.04936674 |
| 97 | Tracheoesophageal fistula (HP:0002575) | 2.03601449 |
| 98 | Patent foramen ovale (HP:0001655) | 2.01230020 |
| 99 | Muscle fiber atrophy (HP:0100295) | 2.01028807 |
| 100 | Abnormality of renal resorption (HP:0011038) | 2.01005863 |
| 101 | Triphalangeal thumb (HP:0001199) | 2.00936509 |
| 102 | Congenital, generalized hypertrichosis (HP:0004540) | 2.00222064 |
| 103 | Abnormal gallbladder physiology (HP:0012438) | 2.00091532 |
| 104 | Cholecystitis (HP:0001082) | 2.00091532 |
| 105 | Glycosuria (HP:0003076) | 2.00062813 |
| 106 | Abnormality of urine glucose concentration (HP:0011016) | 2.00062813 |
| 107 | Respiratory failure (HP:0002878) | 1.99620857 |
| 108 | Abnormality of placental membranes (HP:0011409) | 1.99451212 |
| 109 | Amniotic constriction ring (HP:0009775) | 1.99451212 |
| 110 | Lethargy (HP:0001254) | 1.98232425 |
| 111 | Atrophy/Degeneration involving motor neurons (HP:0007373) | 1.96444746 |
| 112 | Cleft eyelid (HP:0000625) | 1.96392472 |
| 113 | Cervical subluxation (HP:0003308) | 1.95811529 |
| 114 | Pancytopenia (HP:0001876) | 1.95476070 |
| 115 | Nephronophthisis (HP:0000090) | 1.95422064 |
| 116 | Abnormal protein glycosylation (HP:0012346) | 1.95334142 |
| 117 | Abnormal glycosylation (HP:0012345) | 1.95334142 |
| 118 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 1.95334142 |
| 119 | Abnormal protein N-linked glycosylation (HP:0012347) | 1.95334142 |
| 120 | Trismus (HP:0000211) | 1.95216487 |
| 121 | Hypoplasia of the fovea (HP:0007750) | 1.94993141 |
| 122 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 1.94993141 |
| 123 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.94876596 |
| 124 | Embryonal renal neoplasm (HP:0011794) | 1.94493844 |
| 125 | Increased serum lactate (HP:0002151) | 1.93915374 |
| 126 | Respiratory difficulties (HP:0002880) | 1.92611415 |
| 127 | Abnormality of the duodenum (HP:0002246) | 1.92044953 |
| 128 | Vertebral compression fractures (HP:0002953) | 1.91799967 |
| 129 | Prolonged neonatal jaundice (HP:0006579) | 1.90653607 |
| 130 | Recurrent abscess formation (HP:0002722) | 1.89837019 |
| 131 | Facial cleft (HP:0002006) | 1.89727088 |
| 132 | Renal cortical cysts (HP:0000803) | 1.89692496 |
| 133 | Pancreatic islet-cell hyperplasia (HP:0004510) | 1.89634649 |
| 134 | Cellular immunodeficiency (HP:0005374) | 1.89287762 |
| 135 | Increased intramyocellular lipid droplets (HP:0012240) | 1.88695724 |
| 136 | Nephroblastoma (Wilms tumor) (HP:0002667) | 1.87923858 |
| 137 | Amaurosis fugax (HP:0100576) | 1.86696900 |
| 138 | Abnormality of endocrine pancreas physiology (HP:0012093) | 1.86580670 |
| 139 | Abnormality of the pancreatic islet cells (HP:0006476) | 1.86580670 |
| 140 | Hyperglycinuria (HP:0003108) | 1.85747919 |
| 141 | Bifid tongue (HP:0010297) | 1.85716239 |
| 142 | Congenital primary aphakia (HP:0007707) | 1.84639157 |
| 143 | Sparse eyelashes (HP:0000653) | 1.84344969 |
| 144 | Premature ovarian failure (HP:0008209) | 1.84096934 |
| 145 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.83959469 |
| 146 | Abnormal spermatogenesis (HP:0008669) | 1.83879071 |
| 147 | Biliary tract neoplasm (HP:0100574) | 1.82613473 |
| 148 | Sloping forehead (HP:0000340) | 1.82409366 |
| 149 | Neoplasm of the colon (HP:0100273) | 1.82048631 |
| 150 | 3-Methylglutaconic aciduria (HP:0003535) | 1.81806630 |
| 151 | Abnormality of the fovea (HP:0000493) | 1.81543521 |
| 152 | Vaginal fistula (HP:0004320) | 1.81278841 |
| 153 | Abnormality of glycolysis (HP:0004366) | 1.79545178 |
| 154 | Increased serum pyruvate (HP:0003542) | 1.79545178 |
| 155 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 1.79476250 |
| 156 | Sensory axonal neuropathy (HP:0003390) | 1.79027886 |
| 157 | Microvesicular hepatic steatosis (HP:0001414) | 1.77496457 |
| 158 | Short thumb (HP:0009778) | 1.77392189 |
| 159 | Muscle fibrillation (HP:0010546) | 1.75363721 |
| 160 | Glossoptosis (HP:0000162) | 1.74366657 |
| 161 | Pulmonary fibrosis (HP:0002206) | 1.73937211 |
| 162 | Neoplasm of the pancreas (HP:0002894) | 1.73678797 |
| 163 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 1.72602863 |
| 164 | Spinal muscular atrophy (HP:0007269) | 1.71570630 |
| 165 | Intestinal fistula (HP:0100819) | 1.71013836 |
| 166 | Abnormality of the renal collecting system (HP:0004742) | 1.70635373 |
| 167 | Petechiae (HP:0000967) | 1.69650481 |
| 168 | Lymphoma (HP:0002665) | 1.69544221 |
| 169 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 1.69473709 |
| 170 | Absent epiphyses (HP:0010577) | 1.69473709 |
| 171 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.67415248 |
| 172 | Stenosis of the external auditory canal (HP:0000402) | 1.67347411 |
| 173 | Aplasia/Hypoplasia involving the musculature (HP:0001460) | 1.66741081 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 4.40071145 |
| 2 | VRK2 | 3.67119678 |
| 3 | EIF2AK1 | 3.62208435 |
| 4 | WEE1 | 3.47968728 |
| 5 | FRK | 2.69842457 |
| 6 | TRIM28 | 2.65727861 |
| 7 | PLK4 | 2.65626371 |
| 8 | TESK1 | 2.33524311 |
| 9 | PBK | 2.30081141 |
| 10 | BRSK2 | 2.26712567 |
| 11 | SRPK1 | 2.25487815 |
| 12 | ACVR1B | 2.22975465 |
| 13 | TESK2 | 2.22587045 |
| 14 | TSSK6 | 2.21748602 |
| 15 | STK16 | 2.19949048 |
| 16 | PIM2 | 2.19374090 |
| 17 | EIF2AK3 | 2.15931666 |
| 18 | WNK3 | 2.14756954 |
| 19 | CDC7 | 2.09835103 |
| 20 | STK38L | 1.97031080 |
| 21 | NEK1 | 1.85480101 |
| 22 | TNIK | 1.84837503 |
| 23 | MKNK1 | 1.83786987 |
| 24 | MUSK | 1.80898995 |
| 25 | VRK1 | 1.74267454 |
| 26 | NME2 | 1.69771829 |
| 27 | PLK1 | 1.64176079 |
| 28 | ZAK | 1.63387897 |
| 29 | TTK | 1.62466582 |
| 30 | ERBB3 | 1.53763159 |
| 31 | AKT3 | 1.53015971 |
| 32 | PLK3 | 1.51784479 |
| 33 | BRSK1 | 1.50434649 |
| 34 | RPS6KA4 | 1.48904498 |
| 35 | IRAK3 | 1.44651031 |
| 36 | MAP3K12 | 1.37853465 |
| 37 | STK24 | 1.37302060 |
| 38 | MAP4K2 | 1.36461394 |
| 39 | OXSR1 | 1.33889222 |
| 40 | LIMK1 | 1.32905566 |
| 41 | ATR | 1.28948883 |
| 42 | EIF2AK2 | 1.24064025 |
| 43 | SIK3 | 1.17607634 |
| 44 | STK39 | 1.16908442 |
| 45 | BRAF | 1.16546805 |
| 46 | MST4 | 1.13137993 |
| 47 | BCKDK | 1.13117070 |
| 48 | CDK7 | 1.13072625 |
| 49 | AURKB | 1.11454111 |
| 50 | EPHA2 | 1.11395520 |
| 51 | PAK4 | 1.08593701 |
| 52 | CHEK2 | 1.06984623 |
| 53 | MKNK2 | 1.06710944 |
| 54 | AURKA | 1.05903846 |
| 55 | NEK2 | 1.03198931 |
| 56 | TAF1 | 1.02003011 |
| 57 | ARAF | 1.01304304 |
| 58 | NUAK1 | 0.98857021 |
| 59 | CDK8 | 0.94857224 |
| 60 | PASK | 0.93431035 |
| 61 | TGFBR1 | 0.93130244 |
| 62 | IRAK4 | 0.92035267 |
| 63 | CCNB1 | 0.89328699 |
| 64 | BMPR2 | 0.89244174 |
| 65 | PIM1 | 0.87453384 |
| 66 | DYRK3 | 0.86139499 |
| 67 | BCR | 0.86008723 |
| 68 | YES1 | 0.82984190 |
| 69 | PLK2 | 0.80018186 |
| 70 | STK4 | 0.79739052 |
| 71 | CSNK1G1 | 0.79413374 |
| 72 | RPS6KB2 | 0.78521816 |
| 73 | TLK1 | 0.78266577 |
| 74 | MAP3K8 | 0.78025913 |
| 75 | TXK | 0.77557849 |
| 76 | KDR | 0.76637669 |
| 77 | TAOK2 | 0.75189349 |
| 78 | PAK1 | 0.75157623 |
| 79 | NME1 | 0.71187190 |
| 80 | DYRK2 | 0.70809736 |
| 81 | CSNK2A1 | 0.70342823 |
| 82 | IKBKB | 0.70124667 |
| 83 | STK3 | 0.69745826 |
| 84 | MYLK | 0.66723181 |
| 85 | MAP3K4 | 0.64894473 |
| 86 | NEK9 | 0.62607155 |
| 87 | FGFR2 | 0.61654888 |
| 88 | PAK3 | 0.61633933 |
| 89 | CSNK1G2 | 0.61593095 |
| 90 | CHEK1 | 0.60926840 |
| 91 | STK10 | 0.60318795 |
| 92 | CSNK1G3 | 0.60154391 |
| 93 | PRKCE | 0.59277669 |
| 94 | TIE1 | 0.57573518 |
| 95 | CDK4 | 0.56238327 |
| 96 | PDK2 | 0.55197830 |
| 97 | MAP3K11 | 0.54709715 |
| 98 | ADRBK2 | 0.53709009 |
| 99 | DAPK1 | 0.51746024 |
| 100 | INSRR | 0.50918599 |
| 101 | MAP3K14 | 0.48946709 |
| 102 | NEK6 | 0.48406872 |
| 103 | ATM | 0.48302588 |
| 104 | CHUK | 0.48226751 |
| 105 | PRKG2 | 0.48146391 |
| 106 | CASK | 0.48097686 |
| 107 | CSNK2A2 | 0.47777328 |
| 108 | JAK3 | 0.47190581 |
| 109 | PRKCI | 0.46521351 |
| 110 | FER | 0.46245749 |
| 111 | MAP3K3 | 0.45112934 |
| 112 | RPS6KA5 | 0.44660276 |
| 113 | BMPR1B | 0.43715018 |
| 114 | CDK2 | 0.40699578 |
| 115 | FGFR1 | 0.40358681 |
| 116 | ERBB4 | 0.39297368 |
| 117 | RAF1 | 0.39201306 |
| 118 | PRKCG | 0.36353581 |
| 119 | PINK1 | 0.36311023 |
| 120 | NLK | 0.36163242 |
| 121 | GRK1 | 0.36033472 |
| 122 | OBSCN | 0.35894666 |
| 123 | MAPK13 | 0.35101120 |
| 124 | ILK | 0.35059350 |
| 125 | CSF1R | 0.34211786 |
| 126 | CSNK1A1L | 0.33529555 |
| 127 | LYN | 0.33503890 |
| 128 | MAPKAPK3 | 0.32682364 |
| 129 | TEC | 0.32294601 |
| 130 | EGFR | 0.32287538 |
| 131 | PRKACB | 0.28138532 |
| 132 | MELK | 0.27511711 |
| 133 | CAMK2D | 0.27272203 |
| 134 | CAMK2A | 0.26899450 |
| 135 | CDK3 | 0.25717266 |
| 136 | MINK1 | 0.25613318 |
| 137 | IGF1R | 0.21821567 |
| 138 | FLT3 | 0.20505405 |
| 139 | CDK9 | 0.20384943 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.56514945 |
| 2 | DNA replication_Homo sapiens_hsa03030 | 4.49147428 |
| 3 | Mismatch repair_Homo sapiens_hsa03430 | 4.05962352 |
| 4 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.34307542 |
| 5 | RNA polymerase_Homo sapiens_hsa03020 | 3.25772850 |
| 6 | Homologous recombination_Homo sapiens_hsa03440 | 3.03209411 |
| 7 | Base excision repair_Homo sapiens_hsa03410 | 2.86144713 |
| 8 | Spliceosome_Homo sapiens_hsa03040 | 2.79183210 |
| 9 | Ribosome_Homo sapiens_hsa03010 | 2.63696079 |
| 10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.59945443 |
| 11 | RNA transport_Homo sapiens_hsa03013 | 2.59102249 |
| 12 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.49386224 |
| 13 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.37477040 |
| 14 | Cell cycle_Homo sapiens_hsa04110 | 2.28208253 |
| 15 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.24283857 |
| 16 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.09067632 |
| 17 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.08479714 |
| 18 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.99823491 |
| 19 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.97326915 |
| 20 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.96223998 |
| 21 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.94262818 |
| 22 | Basal transcription factors_Homo sapiens_hsa03022 | 1.90141222 |
| 23 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.88300415 |
| 24 | RNA degradation_Homo sapiens_hsa03018 | 1.73405927 |
| 25 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.72468029 |
| 26 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.61981694 |
| 27 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.60136089 |
| 28 | Protein export_Homo sapiens_hsa03060 | 1.41458497 |
| 29 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.41340282 |
| 30 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.36497045 |
| 31 | Purine metabolism_Homo sapiens_hsa00230 | 1.34184263 |
| 32 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.34117205 |
| 33 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.33731403 |
| 34 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.31674053 |
| 35 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.30863667 |
| 36 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.26556601 |
| 37 | Legionellosis_Homo sapiens_hsa05134 | 1.22055526 |
| 38 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.19215780 |
| 39 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.18448291 |
| 40 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.18214644 |
| 41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.13192344 |
| 42 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 1.12352550 |
| 43 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.07750425 |
| 44 | Peroxisome_Homo sapiens_hsa04146 | 1.03582961 |
| 45 | Huntingtons disease_Homo sapiens_hsa05016 | 1.02500395 |
| 46 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.01566725 |
| 47 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.99464990 |
| 48 | Parkinsons disease_Homo sapiens_hsa05012 | 0.95062310 |
| 49 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.94049680 |
| 50 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.92518537 |
| 51 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.91999646 |
| 52 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.91311049 |
| 53 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.88718812 |
| 54 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.86711159 |
| 55 | Phototransduction_Homo sapiens_hsa04744 | 0.84833431 |
| 56 | Shigellosis_Homo sapiens_hsa05131 | 0.79773847 |
| 57 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.77989671 |
| 58 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.75701120 |
| 59 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 0.74886044 |
| 60 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.74268556 |
| 61 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.72635469 |
| 62 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.70780162 |
| 63 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.70686436 |
| 64 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.68649071 |
| 65 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.68145323 |
| 66 | Allograft rejection_Homo sapiens_hsa05330 | 0.67931286 |
| 67 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.65743127 |
| 68 | Galactose metabolism_Homo sapiens_hsa00052 | 0.65661645 |
| 69 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.65491552 |
| 70 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.65326760 |
| 71 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.63161475 |
| 72 | Other glycan degradation_Homo sapiens_hsa00511 | 0.62455713 |
| 73 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.61214766 |
| 74 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.60666943 |
| 75 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.58592262 |
| 76 | Apoptosis_Homo sapiens_hsa04210 | 0.54700370 |
| 77 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.54472705 |
| 78 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.54274947 |
| 79 | HTLV-I infection_Homo sapiens_hsa05166 | 0.52860883 |
| 80 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.52319073 |
| 81 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.52033668 |
| 82 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.50688047 |
| 83 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.50562184 |
| 84 | Phagosome_Homo sapiens_hsa04145 | 0.50400183 |
| 85 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.49822239 |
| 86 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.49552754 |
| 87 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.48573099 |
| 88 | Circadian rhythm_Homo sapiens_hsa04710 | 0.48286605 |
| 89 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.48047134 |
| 90 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.47921133 |
| 91 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.47753526 |
| 92 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.47371570 |
| 93 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.47230459 |
| 94 | Retinol metabolism_Homo sapiens_hsa00830 | 0.45761218 |
| 95 | Carbon metabolism_Homo sapiens_hsa01200 | 0.45688868 |
| 96 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.44809261 |
| 97 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.42033711 |
| 98 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.41782155 |
| 99 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.41470061 |
| 100 | Measles_Homo sapiens_hsa05162 | 0.41274505 |
| 101 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.41192743 |
| 102 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.39566826 |
| 103 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.39467641 |
| 104 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.39072760 |
| 105 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.38821459 |
| 106 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.38597465 |
| 107 | Leishmaniasis_Homo sapiens_hsa05140 | 0.38218625 |
| 108 | Thyroid cancer_Homo sapiens_hsa05216 | 0.37675927 |
| 109 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.37390563 |
| 110 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.37177626 |
| 111 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.35305371 |
| 112 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.34683494 |
| 113 | Asthma_Homo sapiens_hsa05310 | 0.34426381 |
| 114 | Malaria_Homo sapiens_hsa05144 | 0.34244351 |
| 115 | Influenza A_Homo sapiens_hsa05164 | 0.33805913 |
| 116 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.32989048 |
| 117 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.31375290 |
| 118 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.31152347 |
| 119 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.30039167 |
| 120 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.29858818 |
| 121 | Metabolic pathways_Homo sapiens_hsa01100 | 0.28922750 |
| 122 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.28358382 |
| 123 | Alzheimers disease_Homo sapiens_hsa05010 | 0.27869753 |
| 124 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.27696946 |
| 125 | Lysosome_Homo sapiens_hsa04142 | 0.27630079 |
| 126 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.27177366 |
| 127 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.26827969 |
| 128 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.26722198 |
| 129 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.26504141 |
| 130 | Pertussis_Homo sapiens_hsa05133 | 0.25822723 |
| 131 | Taste transduction_Homo sapiens_hsa04742 | 0.25741287 |
| 132 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.25731346 |
| 133 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.25657499 |
| 134 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.25334665 |
| 135 | Olfactory transduction_Homo sapiens_hsa04740 | 0.24946512 |
| 136 | Hepatitis B_Homo sapiens_hsa05161 | 0.23326527 |
| 137 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.23283978 |
| 138 | Small cell lung cancer_Homo sapiens_hsa05222 | 0.23150955 |
| 139 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.21633884 |
| 140 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.21617029 |
| 141 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.20161417 |
| 142 | Adherens junction_Homo sapiens_hsa04520 | 0.19325947 |
| 143 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.18736749 |
| 144 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.17776800 |

