

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | proteasome assembly (GO:0043248) | 5.28775810 |
| 2 | ribosomal small subunit assembly (GO:0000028) | 4.62858606 |
| 3 | DNA deamination (GO:0045006) | 4.61908303 |
| 4 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.46038732 |
| 5 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 4.35335755 |
| 6 | maturation of SSU-rRNA (GO:0030490) | 4.14362938 |
| 7 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 4.14093552 |
| 8 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 4.13769612 |
| 9 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 4.12418781 |
| 10 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 4.08024524 |
| 11 | ribosomal small subunit biogenesis (GO:0042274) | 4.03327713 |
| 12 | ribosomal large subunit biogenesis (GO:0042273) | 4.01062133 |
| 13 | mitotic metaphase plate congression (GO:0007080) | 3.99625456 |
| 14 | DNA double-strand break processing (GO:0000729) | 3.98955166 |
| 15 | viral transcription (GO:0019083) | 3.96357885 |
| 16 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.96045207 |
| 17 | negative regulation of ligase activity (GO:0051352) | 3.96045207 |
| 18 | translational termination (GO:0006415) | 3.93351633 |
| 19 | ATP synthesis coupled proton transport (GO:0015986) | 3.85936759 |
| 20 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.85936759 |
| 21 | formation of translation preinitiation complex (GO:0001731) | 3.78322183 |
| 22 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 3.75811444 |
| 23 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.74708413 |
| 24 | termination of RNA polymerase III transcription (GO:0006386) | 3.74708413 |
| 25 | protein deneddylation (GO:0000338) | 3.70142481 |
| 26 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 3.68380326 |
| 27 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 3.68380326 |
| 28 | DNA replication checkpoint (GO:0000076) | 3.68080882 |
| 29 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.67091812 |
| 30 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 3.66418311 |
| 31 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 3.66418311 |
| 32 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 3.66418311 |
| 33 | 7-methylguanosine mRNA capping (GO:0006370) | 3.66287786 |
| 34 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 3.64224318 |
| 35 | CENP-A containing nucleosome assembly (GO:0034080) | 3.64070802 |
| 36 | establishment of integrated proviral latency (GO:0075713) | 3.64028174 |
| 37 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.62387654 |
| 38 | cotranslational protein targeting to membrane (GO:0006613) | 3.61731797 |
| 39 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO: | 3.61362954 |
| 40 | telomere maintenance via semi-conservative replication (GO:0032201) | 3.59562913 |
| 41 | 7-methylguanosine RNA capping (GO:0009452) | 3.58075278 |
| 42 | RNA capping (GO:0036260) | 3.58075278 |
| 43 | protein targeting to ER (GO:0045047) | 3.56766415 |
| 44 | DNA strand elongation involved in DNA replication (GO:0006271) | 3.56411194 |
| 45 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 3.56376205 |
| 46 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 3.56376205 |
| 47 | regulation of mitotic spindle checkpoint (GO:1903504) | 3.54989774 |
| 48 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 3.54989774 |
| 49 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 3.52061964 |
| 50 | positive regulation of ligase activity (GO:0051351) | 3.51523136 |
| 51 | translational initiation (GO:0006413) | 3.51292085 |
| 52 | translational elongation (GO:0006414) | 3.50066832 |
| 53 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.49267460 |
| 54 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.49267460 |
| 55 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.48640164 |
| 56 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.45817451 |
| 57 | chromatin remodeling at centromere (GO:0031055) | 3.45503179 |
| 58 | rRNA modification (GO:0000154) | 3.45356123 |
| 59 | telomere maintenance via recombination (GO:0000722) | 3.44504116 |
| 60 | maturation of 5.8S rRNA (GO:0000460) | 3.44336180 |
| 61 | DNA ligation (GO:0006266) | 3.44047986 |
| 62 | antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590) | 3.43061294 |
| 63 | cullin deneddylation (GO:0010388) | 3.42578228 |
| 64 | protein localization to endoplasmic reticulum (GO:0070972) | 3.41505781 |
| 65 | purine nucleobase biosynthetic process (GO:0009113) | 3.40577346 |
| 66 | DNA strand elongation (GO:0022616) | 3.38831661 |
| 67 | histone exchange (GO:0043486) | 3.38288153 |
| 68 | metaphase plate congression (GO:0051310) | 3.36329849 |
| 69 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.35989427 |
| 70 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 3.35484760 |
| 71 | attachment of spindle microtubules to kinetochore (GO:0008608) | 3.34222909 |
| 72 | rRNA processing (GO:0006364) | 3.31075106 |
| 73 | translation (GO:0006412) | 3.30985982 |
| 74 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.27961628 |
| 75 | transcription-coupled nucleotide-excision repair (GO:0006283) | 3.25295382 |
| 76 | deoxyribonucleoside monophosphate metabolic process (GO:0009162) | 3.23859233 |
| 77 | regulation of ubiquitin-protein transferase activity (GO:0051438) | 3.23663253 |
| 78 | nucleobase biosynthetic process (GO:0046112) | 3.23574928 |
| 79 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.23273654 |
| 80 | kinetochore organization (GO:0051383) | 3.22986706 |
| 81 | spliceosomal snRNP assembly (GO:0000387) | 3.22721129 |
| 82 | kinetochore assembly (GO:0051382) | 3.21864561 |
| 83 | DNA replication-independent nucleosome organization (GO:0034724) | 3.20195139 |
| 84 | DNA replication-independent nucleosome assembly (GO:0006336) | 3.20195139 |
| 85 | pseudouridine synthesis (GO:0001522) | 3.19826217 |
| 86 | rRNA metabolic process (GO:0016072) | 3.17956968 |
| 87 | protein complex biogenesis (GO:0070271) | 3.17513795 |
| 88 | viral life cycle (GO:0019058) | 3.17417029 |
| 89 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.15723881 |
| 90 | regulation of helicase activity (GO:0051095) | 3.15099992 |
| 91 | regulation of ligase activity (GO:0051340) | 3.14792488 |
| 92 | protein K6-linked ubiquitination (GO:0085020) | 3.13387998 |
| 93 | establishment of chromosome localization (GO:0051303) | 3.13379880 |
| 94 | mitotic recombination (GO:0006312) | 3.12588031 |
| 95 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.12004581 |
| 96 | DNA replication initiation (GO:0006270) | 3.11967962 |
| 97 | DNA damage response, detection of DNA damage (GO:0042769) | 3.11061266 |
| 98 | RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503) | 3.10896248 |
| 99 | termination of RNA polymerase I transcription (GO:0006363) | 3.10388594 |
| 100 | cellular protein complex disassembly (GO:0043624) | 3.09279020 |
| 101 | negative regulation of DNA-dependent DNA replication (GO:2000104) | 3.08694149 |
| 102 | ribosome biogenesis (GO:0042254) | 3.08493303 |
| 103 | sequestering of actin monomers (GO:0042989) | 3.08022738 |
| 104 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.07357047 |
| 105 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.07357047 |
| 106 | NADH dehydrogenase complex assembly (GO:0010257) | 3.07357047 |
| 107 | DNA damage response, signal transduction by p53 class mediator (GO:0030330) | 3.06887998 |
| 108 | transcription elongation from RNA polymerase I promoter (GO:0006362) | 3.05875904 |
| 109 | G1/S transition of mitotic cell cycle (GO:0000082) | 3.05320958 |
| 110 | cell cycle G1/S phase transition (GO:0044843) | 3.05320958 |
| 111 | protein neddylation (GO:0045116) | 3.05211803 |
| 112 | DNA catabolic process, exonucleolytic (GO:0000738) | 3.05150774 |
| 113 | organelle disassembly (GO:1903008) | 3.04896526 |
| 114 | telomere maintenance via telomere lengthening (GO:0010833) | 3.03439223 |
| 115 | resolution of meiotic recombination intermediates (GO:0000712) | 3.03311907 |
| 116 | protein localization to kinetochore (GO:0034501) | 3.02793494 |
| 117 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 3.01462100 |
| 118 | spliceosomal complex assembly (GO:0000245) | 3.01440889 |
| 119 | spindle checkpoint (GO:0031577) | 2.99898272 |
| 120 | histone mRNA metabolic process (GO:0008334) | 2.98217325 |
| 121 | chaperone-mediated protein transport (GO:0072321) | 2.97803567 |
| 122 | ribosome assembly (GO:0042255) | 2.97563435 |
| 123 | transcription from RNA polymerase I promoter (GO:0006360) | 2.97293704 |
| 124 | positive regulation of cell cycle arrest (GO:0071158) | 2.96932337 |
| 125 | cellular component biogenesis (GO:0044085) | 2.96714898 |
| 126 | L-methionine salvage (GO:0071267) | 2.96025184 |
| 127 | L-methionine biosynthetic process (GO:0071265) | 2.96025184 |
| 128 | amino acid salvage (GO:0043102) | 2.96025184 |
| 129 | replication fork processing (GO:0031297) | 2.95008761 |
| 130 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 2.94872760 |
| 131 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.94050719 |
| 132 | mitotic spindle checkpoint (GO:0071174) | 2.93994748 |
| 133 | negative regulation of mitotic metaphase/anaphase transition (GO:0045841) | 2.93241778 |
| 134 | negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100) | 2.93241778 |
| 135 | negative regulation of mitotic sister chromatid segregation (GO:0033048) | 2.93241778 |
| 136 | negative regulation of mitotic sister chromatid separation (GO:2000816) | 2.93241778 |
| 137 | negative regulation of sister chromatid segregation (GO:0033046) | 2.93241778 |
| 138 | response to pheromone (GO:0019236) | 2.90615357 |
| 139 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.89853125 |
| 140 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.89853125 |
| 141 | respiratory electron transport chain (GO:0022904) | 2.85897864 |
| 142 | transcription elongation from RNA polymerase II promoter (GO:0006368) | 2.82590060 |
| 143 | negative regulation of chromosome segregation (GO:0051985) | 2.82098640 |
| 144 | respiratory chain complex IV assembly (GO:0008535) | 2.81876146 |
| 145 | electron transport chain (GO:0022900) | 2.80886878 |
| 146 | protein K11-linked ubiquitination (GO:0070979) | 2.78288015 |
| 147 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.75918478 |
| 148 | establishment of viral latency (GO:0019043) | 2.74884930 |
| 149 | protein-cofactor linkage (GO:0018065) | 2.74212658 |
| 150 | mitotic spindle assembly checkpoint (GO:0007094) | 2.73913277 |
| 151 | spindle assembly checkpoint (GO:0071173) | 2.73314572 |
| 152 | platelet dense granule organization (GO:0060155) | 2.69928847 |
| 153 | intraciliary transport (GO:0042073) | 2.69889308 |
| 154 | double-strand break repair via nonhomologous end joining (GO:0006303) | 2.68780033 |
| 155 | non-recombinational repair (GO:0000726) | 2.68780033 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | E2F7_22180533_ChIP-Seq_HELA_Human | 5.05449033 |
| 2 | * KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 4.43794274 |
| 3 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 4.05556306 |
| 4 | * GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.01988098 |
| 5 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.78152386 |
| 6 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.69951682 |
| 7 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.63519815 |
| 8 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 3.47269421 |
| 9 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.36252936 |
| 10 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 3.21497238 |
| 11 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.96282317 |
| 12 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 2.92025381 |
| 13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.88770207 |
| 14 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.74088504 |
| 15 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.72730962 |
| 16 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 2.72059521 |
| 17 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 2.71675720 |
| 18 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.67996198 |
| 19 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.65503016 |
| 20 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.56412389 |
| 21 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.56367674 |
| 22 | * HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.51615899 |
| 23 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.45077090 |
| 24 | DCP1A_22483619_ChIP-Seq_HELA_Human | 2.39647720 |
| 25 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 2.34759543 |
| 26 | EWS_26573619_Chip-Seq_HEK293_Human | 2.33190676 |
| 27 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.32433902 |
| 28 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 2.31661049 |
| 29 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.18262295 |
| 30 | FUS_26573619_Chip-Seq_HEK293_Human | 2.15913577 |
| 31 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.15395836 |
| 32 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.13054289 |
| 33 | * SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 2.12791009 |
| 34 | * GABP_19822575_ChIP-Seq_HepG2_Human | 2.10837408 |
| 35 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 2.09948317 |
| 36 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.07190337 |
| 37 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.06034357 |
| 38 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.05055867 |
| 39 | * FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.96220967 |
| 40 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 1.95342364 |
| 41 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.93427739 |
| 42 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.92169041 |
| 43 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.91984107 |
| 44 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.90005271 |
| 45 | VDR_22108803_ChIP-Seq_LS180_Human | 1.86810052 |
| 46 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.85315644 |
| 47 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.81307376 |
| 48 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.76569516 |
| 49 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.75796547 |
| 50 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.74715665 |
| 51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.69666642 |
| 52 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.68923855 |
| 53 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.68145328 |
| 54 | P300_19829295_ChIP-Seq_ESCs_Human | 1.66223095 |
| 55 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.61029434 |
| 56 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 1.59591110 |
| 57 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.58238818 |
| 58 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.57305501 |
| 59 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.54483571 |
| 60 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.54029953 |
| 61 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 1.52890199 |
| 62 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.52200453 |
| 63 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 1.50029845 |
| 64 | * POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.49651155 |
| 65 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.46761225 |
| 66 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.44958675 |
| 67 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.43565540 |
| 68 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.42813125 |
| 69 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.42150229 |
| 70 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.41097880 |
| 71 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.40078139 |
| 72 | * SFPI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.39825075 |
| 73 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.39227536 |
| 74 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.37021152 |
| 75 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.33035762 |
| 76 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.32775270 |
| 77 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.32496364 |
| 78 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.32133354 |
| 79 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.30659923 |
| 80 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.28228737 |
| 81 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.25533158 |
| 82 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.24518267 |
| 83 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.23238965 |
| 84 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.23123379 |
| 85 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.23122939 |
| 86 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.22865135 |
| 87 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 1.21049511 |
| 88 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.19832661 |
| 89 | ASXL1_24218140_ChIP-Seq_BMDM_Mouse | 1.16110260 |
| 90 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.14619532 |
| 91 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.13126879 |
| 92 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.12979362 |
| 93 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.12507309 |
| 94 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.11780254 |
| 95 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.11696271 |
| 96 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.11661527 |
| 97 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 1.10998719 |
| 98 | TFEB_21752829_ChIP-Seq_HELA_Human | 1.08863658 |
| 99 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.08302724 |
| 100 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.04735475 |
| 101 | GFI1B_20887958_ChIP-Seq_HPC-7_Mouse | 1.02261699 |
| 102 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.99870589 |
| 103 | * RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.99790117 |
| 104 | * NANOG_19829295_ChIP-Seq_ESCs_Human | 0.96263865 |
| 105 | * SOX2_19829295_ChIP-Seq_ESCs_Human | 0.96263865 |
| 106 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95516067 |
| 107 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 0.94875217 |
| 108 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.94810525 |
| 109 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 0.94808707 |
| 110 | CBP_20019798_ChIP-Seq_JUKART_Human | 0.94475154 |
| 111 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 0.94475154 |
| 112 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.94049626 |
| 113 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 0.93835924 |
| 114 | * KLF4_18555785_ChIP-Seq_MESCs_Mouse | 0.93643359 |
| 115 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 0.92716656 |
| 116 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 0.91972405 |
| 117 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.91079551 |
| 118 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 0.91000366 |
| 119 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 0.90842750 |
| 120 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.90534423 |
| 121 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.90406639 |
| 122 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.89758024 |
| 123 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.89693630 |
| 124 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.89382626 |
| 125 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.89314114 |
| 126 | ER_23166858_ChIP-Seq_MCF-7_Human | 0.89070574 |
| 127 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.88224161 |
| 128 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.87859194 |
| 129 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 0.87494537 |
| 130 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 0.86472753 |
| 131 | * FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.85780030 |
| 132 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.84493251 |
| 133 | KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 0.82854837 |
| 134 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 0.77551534 |
| 135 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.77494847 |
| 136 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.75244764 |
| 137 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.74565200 |
| 138 | TBX5_21415370_ChIP-Seq_HL-1_Mouse | 0.70214525 |
| 139 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 0.68952913 |
| 140 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.68213233 |
| 141 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.68129250 |
| 142 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 0.67716625 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003693_abnormal_embryo_hatching | 5.53740308 |
| 2 | MP0004957_abnormal_blastocyst_morpholog | 3.93466319 |
| 3 | MP0010094_abnormal_chromosome_stability | 3.54938409 |
| 4 | MP0003111_abnormal_nucleus_morphology | 3.44452781 |
| 5 | MP0003077_abnormal_cell_cycle | 3.44002322 |
| 6 | MP0008058_abnormal_DNA_repair | 2.97133901 |
| 7 | MP0003718_maternal_effect | 2.82219486 |
| 8 | MP0008007_abnormal_cellular_replicative | 2.70192941 |
| 9 | MP0008057_abnormal_DNA_replication | 2.63946847 |
| 10 | MP0008932_abnormal_embryonic_tissue | 2.60950938 |
| 11 | MP0003890_abnormal_embryonic-extraembry | 2.40805767 |
| 12 | MP0008789_abnormal_olfactory_epithelium | 2.39693804 |
| 13 | MP0003186_abnormal_redox_activity | 2.31885124 |
| 14 | MP0003786_premature_aging | 2.20423737 |
| 15 | MP0002938_white_spotting | 2.18510371 |
| 16 | MP0001293_anophthalmia | 2.08147335 |
| 17 | MP0009333_abnormal_splenocyte_physiolog | 2.06378689 |
| 18 | MP0003763_abnormal_thymus_physiology | 2.06246003 |
| 19 | MP0005084_abnormal_gallbladder_morpholo | 2.02757278 |
| 20 | MP0009379_abnormal_foot_pigmentation | 1.96550238 |
| 21 | MP0009785_altered_susceptibility_to | 1.88227146 |
| 22 | MP0006072_abnormal_retinal_apoptosis | 1.88082287 |
| 23 | MP0005671_abnormal_response_to | 1.87959956 |
| 24 | MP0005394_taste/olfaction_phenotype | 1.82355735 |
| 25 | MP0005499_abnormal_olfactory_system | 1.82355735 |
| 26 | MP0003880_abnormal_central_pattern | 1.80261621 |
| 27 | MP0001835_abnormal_antigen_presentation | 1.71262900 |
| 28 | MP0003315_abnormal_perineum_morphology | 1.70793223 |
| 29 | MP0003941_abnormal_skin_development | 1.66771113 |
| 30 | MP0003806_abnormal_nucleotide_metabolis | 1.66295885 |
| 31 | MP0000490_abnormal_crypts_of | 1.65076325 |
| 32 | MP0002396_abnormal_hematopoietic_system | 1.64926186 |
| 33 | MP0003937_abnormal_limbs/digits/tail_de | 1.63951926 |
| 34 | MP0001984_abnormal_olfaction | 1.62358454 |
| 35 | MP0002751_abnormal_autonomic_nervous | 1.61867085 |
| 36 | MP0002132_abnormal_respiratory_system | 1.60416901 |
| 37 | MP0008260_abnormal_autophagy | 1.56654825 |
| 38 | MP0002234_abnormal_pharynx_morphology | 1.56285635 |
| 39 | MP0003119_abnormal_digestive_system | 1.55685275 |
| 40 | MP0000049_abnormal_middle_ear | 1.55563216 |
| 41 | MP0006276_abnormal_autonomic_nervous | 1.52744327 |
| 42 | MP0003567_abnormal_fetal_cardiomyocyte | 1.52221379 |
| 43 | MP0002638_abnormal_pupillary_reflex | 1.51823801 |
| 44 | MP0001730_embryonic_growth_arrest | 1.51650432 |
| 45 | MP0004133_heterotaxia | 1.48294240 |
| 46 | MP0000350_abnormal_cell_proliferation | 1.47761335 |
| 47 | MP0002736_abnormal_nociception_after | 1.47638295 |
| 48 | MP0001286_abnormal_eye_development | 1.47549552 |
| 49 | MP0005253_abnormal_eye_physiology | 1.47336338 |
| 50 | MP0002233_abnormal_nose_morphology | 1.47048833 |
| 51 | MP0005451_abnormal_body_composition | 1.45950480 |
| 52 | MP0002019_abnormal_tumor_incidence | 1.42379098 |
| 53 | MP0008877_abnormal_DNA_methylation | 1.42108458 |
| 54 | MP0002148_abnormal_hypersensitivity_rea | 1.40639754 |
| 55 | MP0000566_synostosis | 1.37609801 |
| 56 | MP0001188_hyperpigmentation | 1.35558297 |
| 57 | MP0002398_abnormal_bone_marrow | 1.35440527 |
| 58 | MP0003724_increased_susceptibility_to | 1.35102303 |
| 59 | MP0003121_genomic_imprinting | 1.35076023 |
| 60 | MP0008995_early_reproductive_senescence | 1.34697902 |
| 61 | MP0009697_abnormal_copulation | 1.34290190 |
| 62 | MP0000647_abnormal_sebaceous_gland | 1.31103673 |
| 63 | MP0001853_heart_inflammation | 1.30437445 |
| 64 | MP0003123_paternal_imprinting | 1.28326470 |
| 65 | MP0005408_hypopigmentation | 1.26445627 |
| 66 | MP0005000_abnormal_immune_tolerance | 1.25723559 |
| 67 | MP0000858_altered_metastatic_potential | 1.25379247 |
| 68 | MP0006292_abnormal_olfactory_placode | 1.24696333 |
| 69 | MP0000372_irregular_coat_pigmentation | 1.24621232 |
| 70 | MP0002102_abnormal_ear_morphology | 1.24619037 |
| 71 | MP0000778_abnormal_nervous_system | 1.24434017 |
| 72 | MP0002420_abnormal_adaptive_immunity | 1.24395177 |
| 73 | MP0001819_abnormal_immune_cell | 1.23959758 |
| 74 | MP0000689_abnormal_spleen_morphology | 1.23269131 |
| 75 | MP0002163_abnormal_gland_morphology | 1.23155693 |
| 76 | MP0000313_abnormal_cell_death | 1.22719605 |
| 77 | MP0000631_abnormal_neuroendocrine_gland | 1.22524406 |
| 78 | MP0002653_abnormal_ependyma_morphology | 1.21737635 |
| 79 | MP0002452_abnormal_antigen_presenting | 1.21183116 |
| 80 | MP0002722_abnormal_immune_system | 1.21176064 |
| 81 | MP0005025_abnormal_response_to | 1.20235543 |
| 82 | MP0001800_abnormal_humoral_immune | 1.20033122 |
| 83 | MP0003755_abnormal_palate_morphology | 1.19446052 |
| 84 | MP0004782_abnormal_surfactant_physiolog | 1.18767078 |
| 85 | MP0002723_abnormal_immune_serum | 1.18154230 |
| 86 | MP0001119_abnormal_female_reproductive | 1.17866257 |
| 87 | MP0000716_abnormal_immune_system | 1.15539638 |
| 88 | MP0002429_abnormal_blood_cell | 1.14493881 |
| 89 | MP0001697_abnormal_embryo_size | 1.11582168 |
| 90 | MP0005391_vision/eye_phenotype | 1.11083909 |
| 91 | MP0002282_abnormal_trachea_morphology | 1.10566762 |
| 92 | MP0002697_abnormal_eye_size | 1.07632133 |
| 93 | MP0005187_abnormal_penis_morphology | 1.06830700 |
| 94 | MP0000685_abnormal_immune_system | 1.06815639 |
| 95 | MP0001485_abnormal_pinna_reflex | 1.05918982 |
| 96 | MP0003938_abnormal_ear_development | 1.05589295 |
| 97 | MP0006036_abnormal_mitochondrial_physio | 1.05366470 |
| 98 | MP0000703_abnormal_thymus_morphology | 1.05330453 |
| 99 | MP0003787_abnormal_imprinting | 1.04770164 |
| 100 | MP0005551_abnormal_eye_electrophysiolog | 1.04691100 |
| 101 | MP0005171_absent_coat_pigmentation | 1.03860575 |
| 102 | MP0006082_CNS_inflammation | 1.03679716 |
| 103 | MP0001542_abnormal_bone_strength | 1.03278889 |
| 104 | MP0001324_abnormal_eye_pigmentation | 1.02121761 |
| 105 | MP0002210_abnormal_sex_determination | 1.01003364 |
| 106 | MP0002084_abnormal_developmental_patter | 0.99125903 |
| 107 | MP0002405_respiratory_system_inflammati | 0.98850880 |
| 108 | MP0002090_abnormal_vision | 0.95932832 |
| 109 | MP0005397_hematopoietic_system_phenotyp | 0.95871854 |
| 110 | MP0001545_abnormal_hematopoietic_system | 0.95871854 |
| 111 | MP0002080_prenatal_lethality | 0.95587288 |
| 112 | MP0001986_abnormal_taste_sensitivity | 0.94333992 |
| 113 | MP0003122_maternal_imprinting | 0.93980331 |
| 114 | MP0001177_atelectasis | 0.93433312 |
| 115 | MP0001672_abnormal_embryogenesis/_devel | 0.93159546 |
| 116 | MP0005380_embryogenesis_phenotype | 0.93159546 |
| 117 | MP0005389_reproductive_system_phenotype | 0.92321093 |
| 118 | MP0002752_abnormal_somatic_nervous | 0.92156358 |
| 119 | MP0002419_abnormal_innate_immunity | 0.91516707 |
| 120 | MP0004142_abnormal_muscle_tone | 0.91374556 |
| 121 | MP0003436_decreased_susceptibility_to | 0.90704958 |
| 122 | MP0005195_abnormal_posterior_eye | 0.90398933 |
| 123 | MP0000358_abnormal_cell_content/ | 0.89561846 |
| 124 | MP0001919_abnormal_reproductive_system | 0.89340971 |
| 125 | MP0005395_other_phenotype | 0.88753857 |
| 126 | MP0003283_abnormal_digestive_organ | 0.85965150 |
| 127 | MP0004147_increased_porphyrin_level | 0.85681623 |
| 128 | MP0002111_abnormal_tail_morphology | 0.85362747 |
| 129 | MP0000653_abnormal_sex_gland | 0.85168243 |
| 130 | MP0001145_abnormal_male_reproductive | 0.84063852 |
| 131 | MP0002160_abnormal_reproductive_system | 0.82977208 |
| 132 | MP0001764_abnormal_homeostasis | 0.82889990 |
| 133 | MP0001529_abnormal_vocalization | 0.82216047 |
| 134 | MP0001486_abnormal_startle_reflex | 0.81858292 |
| 135 | MP0002277_abnormal_respiratory_mucosa | 0.81668487 |
| 136 | MP0006054_spinal_hemorrhage | 0.80296779 |
| 137 | MP0003136_yellow_coat_color | 0.79861155 |
| 138 | MP0005367_renal/urinary_system_phenotyp | 0.79790464 |
| 139 | MP0000516_abnormal_urinary_system | 0.79790464 |
| 140 | MP0003984_embryonic_growth_retardation | 0.79070280 |
| 141 | MP0001845_abnormal_inflammatory_respons | 0.78654836 |
| 142 | MP0010155_abnormal_intestine_physiology | 0.77851191 |
| 143 | MP0003861_abnormal_nervous_system | 0.77804075 |
| 144 | MP0001968_abnormal_touch/_nociception | 0.77541276 |
| 145 | MP0001299_abnormal_eye_distance/ | 0.76040354 |
| 146 | MP0002095_abnormal_skin_pigmentation | 0.75359154 |
| 147 | MP0002088_abnormal_embryonic_growth/wei | 0.74889531 |
| 148 | MP0010307_abnormal_tumor_latency | 0.74688145 |
| 149 | MP0002933_joint_inflammation | 0.74249964 |
| 150 | MP0001929_abnormal_gametogenesis | 0.74210252 |
| 151 | MP0003011_delayed_dark_adaptation | 0.74193197 |
| 152 | MP0006035_abnormal_mitochondrial_morpho | 0.73283532 |
| 153 | MP0002085_abnormal_embryonic_tissue | 0.73025671 |
| 154 | MP0004808_abnormal_hematopoietic_stem | 0.72954121 |
| 155 | MP0002928_abnormal_bile_duct | 0.72552943 |
| 156 | MP0000427_abnormal_hair_cycle | 0.72380820 |
| 157 | MP0000465_gastrointestinal_hemorrhage | 0.72251710 |
| 158 | MP0002006_tumorigenesis | 0.71805816 |
| 159 | MP0002184_abnormal_innervation | 0.71471240 |
| 160 | MP0010352_gastrointestinal_tract_polyps | 0.71116375 |
| 161 | MP0001790_abnormal_immune_system | 0.71114019 |
| 162 | MP0005387_immune_system_phenotype | 0.71114019 |
| 163 | MP0010030_abnormal_orbit_morphology | 0.68753761 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Birth length less than 3rd percentile (HP:0003561) | 3.96826998 |
| 2 | Abnormality of cells of the erythroid lineage (HP:0012130) | 3.94811729 |
| 3 | Abnormal number of erythroid precursors (HP:0012131) | 3.79603151 |
| 4 | Reticulocytopenia (HP:0001896) | 3.58351065 |
| 5 | Increased hepatocellular lipid droplets (HP:0006565) | 3.53000770 |
| 6 | Aplastic anemia (HP:0001915) | 3.38585209 |
| 7 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.36031131 |
| 8 | Cerebral hypomyelination (HP:0006808) | 3.35769993 |
| 9 | Oral leukoplakia (HP:0002745) | 3.35644595 |
| 10 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.31141465 |
| 11 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.31141465 |
| 12 | Exertional dyspnea (HP:0002875) | 3.25070202 |
| 13 | Breast hypoplasia (HP:0003187) | 3.20176287 |
| 14 | Abnormality of the labia minora (HP:0012880) | 3.18495133 |
| 15 | Mitochondrial inheritance (HP:0001427) | 3.18279026 |
| 16 | Hepatocellular necrosis (HP:0001404) | 3.18074056 |
| 17 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.16919185 |
| 18 | Rough bone trabeculation (HP:0100670) | 3.15703083 |
| 19 | Pancreatic cysts (HP:0001737) | 3.13632659 |
| 20 | True hermaphroditism (HP:0010459) | 3.10096361 |
| 21 | Pancreatic fibrosis (HP:0100732) | 3.07468756 |
| 22 | Renal Fanconi syndrome (HP:0001994) | 3.05053917 |
| 23 | Lipid accumulation in hepatocytes (HP:0006561) | 3.05010609 |
| 24 | Acute necrotizing encephalopathy (HP:0006965) | 3.02088336 |
| 25 | 3-Methylglutaconic aciduria (HP:0003535) | 3.01099823 |
| 26 | Increased CSF lactate (HP:0002490) | 2.98435465 |
| 27 | Type I transferrin isoform profile (HP:0003642) | 2.88472375 |
| 28 | Hepatic necrosis (HP:0002605) | 2.87486267 |
| 29 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.86590000 |
| 30 | Increased serum lactate (HP:0002151) | 2.85218539 |
| 31 | Macrocytic anemia (HP:0001972) | 2.85038526 |
| 32 | Microretrognathia (HP:0000308) | 2.83763772 |
| 33 | Medial flaring of the eyebrow (HP:0010747) | 2.77203953 |
| 34 | Increased intramyocellular lipid droplets (HP:0012240) | 2.71342005 |
| 35 | Secondary amenorrhea (HP:0000869) | 2.70128745 |
| 36 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 2.65944002 |
| 37 | Carpal bone hypoplasia (HP:0001498) | 2.65776485 |
| 38 | Respiratory difficulties (HP:0002880) | 2.65180518 |
| 39 | Degeneration of anterior horn cells (HP:0002398) | 2.63993451 |
| 40 | Abnormality of the anterior horn cell (HP:0006802) | 2.63993451 |
| 41 | Molar tooth sign on MRI (HP:0002419) | 2.62864868 |
| 42 | Abnormality of midbrain morphology (HP:0002418) | 2.62864868 |
| 43 | Congenital primary aphakia (HP:0007707) | 2.56986523 |
| 44 | Nephrogenic diabetes insipidus (HP:0009806) | 2.52584750 |
| 45 | Gait imbalance (HP:0002141) | 2.52232178 |
| 46 | Pallor (HP:0000980) | 2.50383308 |
| 47 | Patellar aplasia (HP:0006443) | 2.48526949 |
| 48 | Cortical dysplasia (HP:0002539) | 2.44636298 |
| 49 | Premature graying of hair (HP:0002216) | 2.44376494 |
| 50 | Aplasia/Hypoplasia of the patella (HP:0006498) | 2.43055083 |
| 51 | Acute encephalopathy (HP:0006846) | 2.42808478 |
| 52 | Abnormality of glycolysis (HP:0004366) | 2.42608217 |
| 53 | Increased serum pyruvate (HP:0003542) | 2.42608217 |
| 54 | IgM deficiency (HP:0002850) | 2.42412846 |
| 55 | Abnormal trabecular bone morphology (HP:0100671) | 2.42231041 |
| 56 | Septo-optic dysplasia (HP:0100842) | 2.36370421 |
| 57 | Nephronophthisis (HP:0000090) | 2.36059612 |
| 58 | Methylmalonic acidemia (HP:0002912) | 2.35915856 |
| 59 | Abnormality of the preputium (HP:0100587) | 2.35753853 |
| 60 | Genital tract atresia (HP:0001827) | 2.32634621 |
| 61 | Progressive macrocephaly (HP:0004481) | 2.31006763 |
| 62 | Meckel diverticulum (HP:0002245) | 2.30638081 |
| 63 | Methylmalonic aciduria (HP:0012120) | 2.30201645 |
| 64 | Vaginal atresia (HP:0000148) | 2.28908574 |
| 65 | Premature ovarian failure (HP:0008209) | 2.28037523 |
| 66 | Cerebral edema (HP:0002181) | 2.27557072 |
| 67 | Abnormal lung lobation (HP:0002101) | 2.24421371 |
| 68 | Cleft eyelid (HP:0000625) | 2.24366769 |
| 69 | Agnosia (HP:0010524) | 2.22520052 |
| 70 | Increased muscle lipid content (HP:0009058) | 2.19206568 |
| 71 | Supernumerary spleens (HP:0009799) | 2.18706719 |
| 72 | Abnormality of the ileum (HP:0001549) | 2.18158597 |
| 73 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.17833681 |
| 74 | Exercise intolerance (HP:0003546) | 2.17386290 |
| 75 | Stenosis of the external auditory canal (HP:0000402) | 2.16143478 |
| 76 | Abnormality of chromosome stability (HP:0003220) | 2.15640640 |
| 77 | Abnormality of serum amino acid levels (HP:0003112) | 2.15518633 |
| 78 | Recurrent abscess formation (HP:0002722) | 2.15323456 |
| 79 | Trismus (HP:0000211) | 2.14794700 |
| 80 | Bifid tongue (HP:0010297) | 2.14624382 |
| 81 | Elevated erythrocyte sedimentation rate (HP:0003565) | 2.13849016 |
| 82 | Muscle fiber atrophy (HP:0100295) | 2.13661302 |
| 83 | Bone marrow hypocellularity (HP:0005528) | 2.13166532 |
| 84 | Type 2 muscle fiber atrophy (HP:0003554) | 2.12401201 |
| 85 | Abolished electroretinogram (ERG) (HP:0000550) | 2.11503868 |
| 86 | Poor head control (HP:0002421) | 2.10460453 |
| 87 | Sclerocornea (HP:0000647) | 2.09846633 |
| 88 | Microvesicular hepatic steatosis (HP:0001414) | 2.09115975 |
| 89 | Hyperglycinemia (HP:0002154) | 2.07692329 |
| 90 | Absent thumb (HP:0009777) | 2.07050315 |
| 91 | Thrombocytosis (HP:0001894) | 2.06925909 |
| 92 | Neoplasm of the adrenal gland (HP:0100631) | 2.06463778 |
| 93 | Lactic acidosis (HP:0003128) | 2.06231129 |
| 94 | Bilateral microphthalmos (HP:0007633) | 2.05707441 |
| 95 | Chromsome breakage (HP:0040012) | 2.04922713 |
| 96 | Optic nerve hypoplasia (HP:0000609) | 2.04764117 |
| 97 | Multiple enchondromatosis (HP:0005701) | 2.04307593 |
| 98 | Respiratory failure (HP:0002878) | 2.03483881 |
| 99 | Prolonged neonatal jaundice (HP:0006579) | 2.02709846 |
| 100 | Anencephaly (HP:0002323) | 2.01786301 |
| 101 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.00936990 |
| 102 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.00936990 |
| 103 | Abnormal protein glycosylation (HP:0012346) | 2.00936990 |
| 104 | Abnormal glycosylation (HP:0012345) | 2.00936990 |
| 105 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.00817850 |
| 106 | IgG deficiency (HP:0004315) | 1.99053884 |
| 107 | Myelodysplasia (HP:0002863) | 1.97632586 |
| 108 | Abnormality of the renal medulla (HP:0100957) | 1.97080589 |
| 109 | Reduced antithrombin III activity (HP:0001976) | 1.96692216 |
| 110 | Progressive inability to walk (HP:0002505) | 1.96489374 |
| 111 | CNS hypomyelination (HP:0003429) | 1.95700267 |
| 112 | Triphalangeal thumb (HP:0001199) | 1.95462268 |
| 113 | Sparse eyelashes (HP:0000653) | 1.95458566 |
| 114 | Abnormality of methionine metabolism (HP:0010901) | 1.94570254 |
| 115 | Colon cancer (HP:0003003) | 1.93874855 |
| 116 | Optic disc pallor (HP:0000543) | 1.93553117 |
| 117 | 11 pairs of ribs (HP:0000878) | 1.93501297 |
| 118 | Selective tooth agenesis (HP:0001592) | 1.92448471 |
| 119 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.92423216 |
| 120 | Neoplasm of the adrenal cortex (HP:0100641) | 1.91720456 |
| 121 | Preaxial hand polydactyly (HP:0001177) | 1.91497373 |
| 122 | Inability to walk (HP:0002540) | 1.90922047 |
| 123 | Pancytopenia (HP:0001876) | 1.90752588 |
| 124 | Abnormality of alanine metabolism (HP:0010916) | 1.90660382 |
| 125 | Hyperalaninemia (HP:0003348) | 1.90660382 |
| 126 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.90660382 |
| 127 | Leukodystrophy (HP:0002415) | 1.90032625 |
| 128 | Absent septum pellucidum (HP:0001331) | 1.89767324 |
| 129 | Pulmonary fibrosis (HP:0002206) | 1.89596643 |
| 130 | Irregular epiphyses (HP:0010582) | 1.88985914 |
| 131 | Recurrent bacterial skin infections (HP:0005406) | 1.87346576 |
| 132 | Dandy-Walker malformation (HP:0001305) | 1.87037881 |
| 133 | Poor coordination (HP:0002370) | 1.86385282 |
| 134 | Small intestinal stenosis (HP:0012848) | 1.85989306 |
| 135 | Duodenal stenosis (HP:0100867) | 1.85989306 |
| 136 | Cellular immunodeficiency (HP:0005374) | 1.85240550 |
| 137 | Abnormality of the septum pellucidum (HP:0007375) | 1.84764945 |
| 138 | Abnormality of the umbilical cord (HP:0010881) | 1.84030079 |
| 139 | CNS demyelination (HP:0007305) | 1.83857183 |
| 140 | Esophageal atresia (HP:0002032) | 1.82643535 |
| 141 | Gastrointestinal atresia (HP:0002589) | 1.82559620 |
| 142 | Glossoptosis (HP:0000162) | 1.82554886 |
| 143 | Abnormal hemoglobin (HP:0011902) | 1.82048860 |
| 144 | Postaxial foot polydactyly (HP:0001830) | 1.79980424 |
| 145 | Sloping forehead (HP:0000340) | 1.79063065 |
| 146 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.78370182 |
| 147 | Intestinal atresia (HP:0011100) | 1.78060176 |
| 148 | Abnormality of renal resorption (HP:0011038) | 1.77890946 |
| 149 | Renal cortical cysts (HP:0000803) | 1.74717409 |
| 150 | Abnormality of glycine metabolism (HP:0010895) | 1.74623616 |
| 151 | Abnormality of serine family amino acid metabolism (HP:0010894) | 1.74623616 |
| 152 | Anophthalmia (HP:0000528) | 1.73988219 |
| 153 | Abnormality of the duodenum (HP:0002246) | 1.73319454 |
| 154 | Adrenal hypoplasia (HP:0000835) | 1.72709034 |
| 155 | Postaxial hand polydactyly (HP:0001162) | 1.71618908 |
| 156 | Broad foot (HP:0001769) | 1.70161510 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | BUB1 | 5.12359576 |
| 2 | NME2 | 3.42604028 |
| 3 | STK16 | 3.42316319 |
| 4 | EIF2AK1 | 3.27426015 |
| 5 | WEE1 | 3.05009632 |
| 6 | PLK4 | 2.84596172 |
| 7 | VRK2 | 2.68520992 |
| 8 | TRIM28 | 2.59528031 |
| 9 | PBK | 2.41977653 |
| 10 | TESK2 | 2.40902360 |
| 11 | ACVR1B | 2.31837153 |
| 12 | WNK3 | 2.31297691 |
| 13 | EIF2AK3 | 2.20521249 |
| 14 | CDC7 | 2.17926779 |
| 15 | SRPK1 | 2.13167810 |
| 16 | VRK1 | 2.11331978 |
| 17 | CASK | 2.00243872 |
| 18 | CCNB1 | 1.90542840 |
| 19 | PIM2 | 1.70747778 |
| 20 | MAP3K4 | 1.67801404 |
| 21 | TLK1 | 1.64571725 |
| 22 | BRSK2 | 1.60242870 |
| 23 | DYRK3 | 1.57238260 |
| 24 | ERBB3 | 1.57088944 |
| 25 | TTK | 1.53848383 |
| 26 | PLK1 | 1.53618090 |
| 27 | RPS6KA4 | 1.53455882 |
| 28 | TSSK6 | 1.44196991 |
| 29 | BRAF | 1.39808537 |
| 30 | CSNK1G1 | 1.34980062 |
| 31 | NEK2 | 1.34617813 |
| 32 | IRAK3 | 1.34174773 |
| 33 | MST4 | 1.33931223 |
| 34 | MAP2K7 | 1.33917670 |
| 35 | AURKB | 1.32725196 |
| 36 | CDK8 | 1.32191742 |
| 37 | CSNK1G2 | 1.30783825 |
| 38 | MKNK1 | 1.29713790 |
| 39 | ARAF | 1.28314943 |
| 40 | MAP4K2 | 1.25088464 |
| 41 | IRAK4 | 1.24353182 |
| 42 | AURKA | 1.23083831 |
| 43 | LIMK1 | 1.21986152 |
| 44 | TESK1 | 1.20340435 |
| 45 | FRK | 1.19846227 |
| 46 | TNIK | 1.16769032 |
| 47 | PLK3 | 1.16698601 |
| 48 | PLK2 | 1.16648980 |
| 49 | ZAK | 1.11467148 |
| 50 | TXK | 1.10222230 |
| 51 | CSNK1A1L | 1.07797727 |
| 52 | BMPR1B | 1.07226363 |
| 53 | TGFBR1 | 1.04949803 |
| 54 | DYRK2 | 1.04727998 |
| 55 | CDK19 | 1.04434787 |
| 56 | KDR | 1.02543817 |
| 57 | NME1 | 1.01986159 |
| 58 | CDK7 | 1.00630313 |
| 59 | MAP4K1 | 0.98420334 |
| 60 | ZAP70 | 0.97058676 |
| 61 | CHEK2 | 0.95583489 |
| 62 | MAP3K12 | 0.94931366 |
| 63 | STK38L | 0.90912653 |
| 64 | MKNK2 | 0.90547318 |
| 65 | MOS | 0.90285456 |
| 66 | EIF2AK2 | 0.90002720 |
| 67 | GRK1 | 0.86704977 |
| 68 | MAPK13 | 0.86653602 |
| 69 | ADRBK2 | 0.86418977 |
| 70 | MAP3K8 | 0.85893770 |
| 71 | PDK2 | 0.85684913 |
| 72 | TAF1 | 0.84839600 |
| 73 | NUAK1 | 0.84146474 |
| 74 | TBK1 | 0.83916592 |
| 75 | MAP3K11 | 0.83807752 |
| 76 | ATR | 0.80333809 |
| 77 | OXSR1 | 0.78826230 |
| 78 | TEC | 0.77511052 |
| 79 | STK10 | 0.77233470 |
| 80 | RPS6KB2 | 0.76340548 |
| 81 | ILK | 0.75495991 |
| 82 | NLK | 0.75261612 |
| 83 | BRSK1 | 0.74440144 |
| 84 | STK3 | 0.73928528 |
| 85 | MARK1 | 0.72494323 |
| 86 | NEK9 | 0.72026758 |
| 87 | STK39 | 0.71718201 |
| 88 | EPHA2 | 0.71617006 |
| 89 | ABL2 | 0.69937942 |
| 90 | ERBB4 | 0.69701658 |
| 91 | IKBKE | 0.69589883 |
| 92 | BLK | 0.68106190 |
| 93 | JAK3 | 0.66870150 |
| 94 | PAK1 | 0.66657653 |
| 95 | CSNK2A1 | 0.66564291 |
| 96 | MINK1 | 0.66457968 |
| 97 | PAK4 | 0.65875771 |
| 98 | TYK2 | 0.65311402 |
| 99 | RPS6KA5 | 0.64754878 |
| 100 | PASK | 0.64317547 |
| 101 | BMPR2 | 0.63682527 |
| 102 | PIM1 | 0.63272359 |
| 103 | MELK | 0.63021789 |
| 104 | PINK1 | 0.62849001 |
| 105 | BRD4 | 0.61384627 |
| 106 | IRAK1 | 0.58997361 |
| 107 | STK4 | 0.58943181 |
| 108 | TIE1 | 0.57502733 |
| 109 | PNCK | 0.57362308 |
| 110 | ATM | 0.57004700 |
| 111 | PRKCI | 0.56192535 |
| 112 | KIT | 0.55938175 |
| 113 | PRKCG | 0.55527576 |
| 114 | IKBKB | 0.54606440 |
| 115 | INSRR | 0.53464786 |
| 116 | BCR | 0.53370903 |
| 117 | CLK1 | 0.52966873 |
| 118 | PRKCE | 0.51901467 |
| 119 | CSNK2A2 | 0.49498690 |
| 120 | MAP3K14 | 0.48046552 |
| 121 | STK24 | 0.47149918 |
| 122 | NEK1 | 0.46133183 |
| 123 | BTK | 0.44511263 |
| 124 | CDK3 | 0.44021903 |
| 125 | MAP3K3 | 0.42865463 |
| 126 | CDK4 | 0.42860820 |
| 127 | LRRK2 | 0.41136359 |
| 128 | MAP2K3 | 0.38171530 |
| 129 | CSNK1G3 | 0.37308833 |
| 130 | CHEK1 | 0.37294274 |
| 131 | MYLK | 0.36970301 |
| 132 | LYN | 0.36176333 |
| 133 | MUSK | 0.36008314 |
| 134 | BCKDK | 0.34968044 |
| 135 | FGFR1 | 0.34647361 |
| 136 | PAK3 | 0.34176978 |
| 137 | IRAK2 | 0.33697627 |
| 138 | DYRK1A | 0.33533473 |
| 139 | CSNK1E | 0.32583323 |
| 140 | CSNK1A1 | 0.32580060 |
| 141 | EPHA4 | 0.31078382 |
| 142 | MAP2K6 | 0.30536730 |
| 143 | LATS1 | 0.27568457 |
| 144 | WNK4 | 0.27523209 |
| 145 | FGFR2 | 0.27358174 |
| 146 | SIK3 | 0.26582598 |
| 147 | CAMK2A | 0.26485572 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 4.63988440 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 4.14524699 |
| 3 | RNA polymerase_Homo sapiens_hsa03020 | 3.90044132 |
| 4 | DNA replication_Homo sapiens_hsa03030 | 3.69007220 |
| 5 | Mismatch repair_Homo sapiens_hsa03430 | 3.09659534 |
| 6 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 3.00977671 |
| 7 | Spliceosome_Homo sapiens_hsa03040 | 2.66180836 |
| 8 | Base excision repair_Homo sapiens_hsa03410 | 2.65526670 |
| 9 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 2.61060892 |
| 10 | Nucleotide excision repair_Homo sapiens_hsa03420 | 2.56552335 |
| 11 | Homologous recombination_Homo sapiens_hsa03440 | 2.55025180 |
| 12 | Protein export_Homo sapiens_hsa03060 | 2.41642797 |
| 13 | RNA transport_Homo sapiens_hsa03013 | 2.36922852 |
| 14 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.11749780 |
| 15 | Basal transcription factors_Homo sapiens_hsa03022 | 2.11725335 |
| 16 | Cell cycle_Homo sapiens_hsa04110 | 2.10879577 |
| 17 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.99069998 |
| 18 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.98016168 |
| 19 | RNA degradation_Homo sapiens_hsa03018 | 1.91497830 |
| 20 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.82339366 |
| 21 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.77944189 |
| 22 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 1.64407130 |
| 23 | Parkinsons disease_Homo sapiens_hsa05012 | 1.57497424 |
| 24 | One carbon pool by folate_Homo sapiens_hsa00670 | 1.48460076 |
| 25 | Non-homologous end-joining_Homo sapiens_hsa03450 | 1.47490925 |
| 26 | p53 signaling pathway_Homo sapiens_hsa04115 | 1.40601040 |
| 27 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.40195069 |
| 28 | Purine metabolism_Homo sapiens_hsa00230 | 1.39465250 |
| 29 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.37726095 |
| 30 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.35532760 |
| 31 | Huntingtons disease_Homo sapiens_hsa05016 | 1.32325630 |
| 32 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.29006493 |
| 33 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.25992312 |
| 34 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.25178265 |
| 35 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 1.19467043 |
| 36 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.17631856 |
| 37 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.16994221 |
| 38 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.11919956 |
| 39 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.08298335 |
| 40 | Sulfur relay system_Homo sapiens_hsa04122 | 1.02792831 |
| 41 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.00879148 |
| 42 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.00523741 |
| 43 | Peroxisome_Homo sapiens_hsa04146 | 0.98273284 |
| 44 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.97431960 |
| 45 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.95730948 |
| 46 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.92050138 |
| 47 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.91670776 |
| 48 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.91479824 |
| 49 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.90627256 |
| 50 | Herpes simplex infection_Homo sapiens_hsa05168 | 0.90382517 |
| 51 | Allograft rejection_Homo sapiens_hsa05330 | 0.90113185 |
| 52 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.88657083 |
| 53 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.85230924 |
| 54 | Legionellosis_Homo sapiens_hsa05134 | 0.83603662 |
| 55 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.80044663 |
| 56 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.79493871 |
| 57 | Alzheimers disease_Homo sapiens_hsa05010 | 0.78233853 |
| 58 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.76480406 |
| 59 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.75965686 |
| 60 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.74809868 |
| 61 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.74533954 |
| 62 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.71340704 |
| 63 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.69387515 |
| 64 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.67259452 |
| 65 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.66029739 |
| 66 | Measles_Homo sapiens_hsa05162 | 0.64842052 |
| 67 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.64757126 |
| 68 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.61875133 |
| 69 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.61504883 |
| 70 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 0.60618457 |
| 71 | Nicotine addiction_Homo sapiens_hsa05033 | 0.60360617 |
| 72 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.59590390 |
| 73 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.59428036 |
| 74 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.58019425 |
| 75 | Shigellosis_Homo sapiens_hsa05131 | 0.57581499 |
| 76 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.57063231 |
| 77 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.56668308 |
| 78 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.56006263 |
| 79 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.54636862 |
| 80 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.53321231 |
| 81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.52660286 |
| 82 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.51980256 |
| 83 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.51871011 |
| 84 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.51275498 |
| 85 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.50802897 |
| 86 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50164129 |
| 87 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.49894570 |
| 88 | Asthma_Homo sapiens_hsa05310 | 0.48855845 |
| 89 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.48752371 |
| 90 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.48446694 |
| 91 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.48239770 |
| 92 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.48080939 |
| 93 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.46721214 |
| 94 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.46245745 |
| 95 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.45584075 |
| 96 | HTLV-I infection_Homo sapiens_hsa05166 | 0.45409453 |
| 97 | Metabolic pathways_Homo sapiens_hsa01100 | 0.44849391 |
| 98 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.44545490 |
| 99 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.44165368 |
| 100 | Leishmaniasis_Homo sapiens_hsa05140 | 0.43486649 |
| 101 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 0.43370459 |
| 102 | Apoptosis_Homo sapiens_hsa04210 | 0.43170719 |
| 103 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 0.39690039 |
| 104 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.39612716 |
| 105 | Olfactory transduction_Homo sapiens_hsa04740 | 0.39429337 |
| 106 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.39145362 |
| 107 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.39142093 |
| 108 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.36427728 |
| 109 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.35703223 |
| 110 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.35283539 |
| 111 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.34533121 |
| 112 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.33846775 |
| 113 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.33630195 |
| 114 | Influenza A_Homo sapiens_hsa05164 | 0.33279710 |
| 115 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.31291333 |
| 116 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.30734656 |
| 117 | Other glycan degradation_Homo sapiens_hsa00511 | 0.30657178 |
| 118 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.30396695 |
| 119 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.29821519 |
| 120 | Malaria_Homo sapiens_hsa05144 | 0.29466460 |
| 121 | Hepatitis B_Homo sapiens_hsa05161 | 0.29359709 |
| 122 | Thyroid cancer_Homo sapiens_hsa05216 | 0.27884929 |
| 123 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.27168735 |
| 124 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.25730096 |
| 125 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.24984597 |
| 126 | Circadian rhythm_Homo sapiens_hsa04710 | 0.24851125 |
| 127 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.23712369 |
| 128 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.22801829 |
| 129 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.22337576 |
| 130 | Phototransduction_Homo sapiens_hsa04744 | 0.22191828 |
| 131 | Taste transduction_Homo sapiens_hsa04742 | 0.21099793 |
| 132 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.20164589 |
| 133 | Pertussis_Homo sapiens_hsa05133 | 0.19894053 |
| 134 | Alcoholism_Homo sapiens_hsa05034 | 0.19175791 |
| 135 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.18904664 |
| 136 | Phagosome_Homo sapiens_hsa04145 | 0.18232386 |
| 137 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.17656682 |
| 138 | Carbon metabolism_Homo sapiens_hsa01200 | 0.17553000 |
| 139 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.16159104 |
| 140 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.16149074 |
| 141 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 0.14823268 |
| 142 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.13482768 |
| 143 | Viral myocarditis_Homo sapiens_hsa05416 | 0.13046221 |
| 144 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.12644565 |

