COMT

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1mitotic sister chromatid cohesion (GO:0007064)6.30292064
2interkinetic nuclear migration (GO:0022027)5.66240988
3cytoplasmic mRNA processing body assembly (GO:0033962)4.81045054
4deoxyribonucleoside monophosphate metabolic process (GO:0009162)4.74401144
5regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450914.67087070
6embryonic retina morphogenesis in camera-type eye (GO:0060059)4.51435521
7endocardial cushion development (GO:0003197)4.34558179
8lymphangiogenesis (GO:0001946)4.33267432
9pericardium development (GO:0060039)4.31736272
10kinetochore organization (GO:0051383)4.30837690
11regulation of acrosome reaction (GO:0060046)4.23639456
12artery development (GO:0060840)4.08926244
13radial glial cell differentiation (GO:0060019)4.01183585
14GDP-mannose metabolic process (GO:0019673)3.90851339
15regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060211)3.86147099
16positive regulation of nuclear-transcribed mRNA poly(A) tail shortening (GO:0060213)3.86147099
17pre-miRNA processing (GO:0031054)3.83912379
18kinetochore assembly (GO:0051382)3.74539522
19regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307)3.72084656
20lateral sprouting from an epithelium (GO:0060601)3.67254559
21regulation of cardioblast differentiation (GO:0051890)3.66611228
22protein maturation by protein folding (GO:0022417)3.65077550
23COPI coating of Golgi vesicle (GO:0048205)3.63774607
24Golgi transport vesicle coating (GO:0048200)3.63774607
25purine nucleotide salvage (GO:0032261)3.60807433
26positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO3.51054371
27regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay (GO:1900151)3.51054371
28hippo signaling (GO:0035329)3.48428136
29negative regulation of DNA repair (GO:0045738)3.45080226
30cell migration involved in heart development (GO:0060973)3.42344979
31response to thyroid hormone (GO:0097066)3.39633836
32regulation of axon extension involved in axon guidance (GO:0048841)3.39231938
33midgut development (GO:0007494)3.38483479
34maintenance of protein localization in endoplasmic reticulum (GO:0035437)3.38109438
35embryonic body morphogenesis (GO:0010172)3.38012452
36nucleotide salvage (GO:0043173)3.35433814
37protein retention in ER lumen (GO:0006621)3.35192291
38negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471)3.30712837
39nucleus localization (GO:0051647)3.29011695
40pentose-phosphate shunt (GO:0006098)3.28470998
41atrial septum morphogenesis (GO:0060413)3.27707509
42pinocytosis (GO:0006907)3.24309270
43regulation of RNA export from nucleus (GO:0046831)3.22266288
44anatomical structure arrangement (GO:0048532)3.15801528
45erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)3.11478783
46L-phenylalanine metabolic process (GO:0006558)3.11478783
47head development (GO:0060322)3.09984586
48mature B cell differentiation involved in immune response (GO:0002313)3.09036508
49lipopolysaccharide biosynthetic process (GO:0009103)3.08998794
50regulation of cardioblast proliferation (GO:0003264)3.08841563
51regulation of secondary heart field cardioblast proliferation (GO:0003266)3.08841563
52endocardial cushion morphogenesis (GO:0003203)3.08652524
53purine deoxyribonucleotide catabolic process (GO:0009155)3.07186951
54autophagic vacuole fusion (GO:0000046)3.06213944
55UV protection (GO:0009650)3.06056996
56glucose catabolic process (GO:0006007)3.05500645
57atrioventricular valve morphogenesis (GO:0003181)3.02264877
58regulation of DNA endoreduplication (GO:0032875)3.01485515
59glycosphingolipid catabolic process (GO:0046479)3.00318276
60embryonic forelimb morphogenesis (GO:0035115)2.98091085
61cranial suture morphogenesis (GO:0060363)2.94926093
62response to peptidoglycan (GO:0032494)2.94483819
63regulation of sister chromatid cohesion (GO:0007063)2.92350273
64nuclear pore complex assembly (GO:0051292)2.92308617
65oligosaccharide catabolic process (GO:0009313)2.91481774
66regulation of axon guidance (GO:1902667)2.91044309
67nucleoside salvage (GO:0043174)2.88839613
68histone H3-K4 trimethylation (GO:0080182)2.87700653
69notochord development (GO:0030903)2.87555372
70glutathione biosynthetic process (GO:0006750)2.87401735
71somatic stem cell division (GO:0048103)2.87165528
72regulation of clathrin-mediated endocytosis (GO:2000369)2.86694905
73negative regulation of B cell apoptotic process (GO:0002903)2.85926380
74positive regulation of meiosis (GO:0045836)2.85583118
75body morphogenesis (GO:0010171)2.84445821
76ribosomal small subunit biogenesis (GO:0042274)2.84251550
77proline biosynthetic process (GO:0006561)2.82759269
78regulation of Wnt signaling pathway, planar cell polarity pathway (GO:2000095)2.82074477
79tongue development (GO:0043586)2.82053186
80pentose metabolic process (GO:0019321)2.81603790
81lipopolysaccharide metabolic process (GO:0008653)2.80774912
82type B pancreatic cell proliferation (GO:0044342)2.80477448
83venous blood vessel morphogenesis (GO:0048845)2.80081567
842-deoxyribonucleotide biosynthetic process (GO:0009265)2.79754126
85deoxyribose phosphate biosynthetic process (GO:0046385)2.79754126
86glucocorticoid receptor signaling pathway (GO:0042921)2.78595887
87regulation of heart morphogenesis (GO:2000826)2.78340236
88dopaminergic neuron differentiation (GO:0071542)2.77897094
89pyrimidine-containing compound salvage (GO:0008655)2.77459978
90pyrimidine nucleoside salvage (GO:0043097)2.77459978
91retrograde transport, vesicle recycling within Golgi (GO:0000301)2.77288443
92craniofacial suture morphogenesis (GO:0097094)2.75786235
93mitochondrial calcium ion transport (GO:0006851)2.75694697
94negative regulation of myeloid cell apoptotic process (GO:0033033)2.75485700
95chondrocyte proliferation (GO:0035988)2.75477641
96valine metabolic process (GO:0006573)2.74603890
97negative regulation of release of cytochrome c from mitochondria (GO:0090201)2.73979156
98cellular response to thyroid hormone stimulus (GO:0097067)2.73552678
99regulation of nephron tubule epithelial cell differentiation (GO:0072182)2.72964411
100positive regulation of fatty acid beta-oxidation (GO:0032000)2.71889073
101protein targeting to Golgi (GO:0000042)2.71884582
102glycolipid catabolic process (GO:0019377)2.71204893
103NLS-bearing protein import into nucleus (GO:0006607)2.70364874
104chondrocyte development (GO:0002063)2.68484174
105embryonic camera-type eye morphogenesis (GO:0048596)2.68236390
106positive regulation of mitotic sister chromatid separation (GO:1901970)2.67712298
107positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.67712298
108positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.67712298
109barbed-end actin filament capping (GO:0051016)2.64319168
110serotonin metabolic process (GO:0042428)2.63883232
111NADPH regeneration (GO:0006740)2.63181150
112heart valve morphogenesis (GO:0003179)2.60452502
113nonribosomal peptide biosynthetic process (GO:0019184)2.60376142
114negative regulation of receptor-mediated endocytosis (GO:0048261)2.59840816
115mesenchyme morphogenesis (GO:0072132)2.59008312
116negative regulation of erythrocyte differentiation (GO:0045647)2.58795100
117negative regulation of vascular permeability (GO:0043116)2.58671874
118negative regulation of nitric oxide biosynthetic process (GO:0045019)2.57798428
119positive regulation of pathway-restricted SMAD protein phosphorylation (GO:0010862)2.57693503
120prostanoid biosynthetic process (GO:0046457)2.57420562
121prostaglandin biosynthetic process (GO:0001516)2.57420562
122mitochondrial ATP synthesis coupled proton transport (GO:0042776)2.56679966
123forebrain neuron development (GO:0021884)2.56511525
124heart morphogenesis (GO:0003007)2.56288710
125positive regulation of meiotic cell cycle (GO:0051446)2.55937003
126hyaluronan catabolic process (GO:0030214)2.55622321
127regulation of stem cell maintenance (GO:2000036)2.55439117
128apical protein localization (GO:0045176)2.55321425
129purine deoxyribonucleotide metabolic process (GO:0009151)2.54388232
130positive regulation of mRNA 3-end processing (GO:0031442)2.54371095
131regulation of mRNA 3-end processing (GO:0031440)2.53968890
132adhesion of symbiont to host (GO:0044406)2.53089336
133antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent (GO:2.52738230
134proteasome assembly (GO:0043248)2.52550029
135positive regulation of mitochondrial calcium ion concentration (GO:0051561)2.52410385
136response to testosterone (GO:0033574)2.51788699
137deoxyribonucleotide catabolic process (GO:0009264)2.50980400
138oxaloacetate metabolic process (GO:0006107)2.50746494
139regulation of superoxide anion generation (GO:0032928)2.50619698
140negative regulation of axon extension involved in axon guidance (GO:0048843)2.47752113
141antigen processing and presentation of exogenous peptide antigen via MHC class I (GO:0042590)2.46475231
142deoxyribose phosphate catabolic process (GO:0046386)2.46194303
143negative regulation of neurotransmitter secretion (GO:0046929)2.45085694
144amino sugar catabolic process (GO:0046348)2.44694065
145negative regulation of hydrogen peroxide-induced cell death (GO:1903206)2.44619070
146forelimb morphogenesis (GO:0035136)2.44007336
147establishment of protein localization to Golgi (GO:0072600)2.43920220
148regulation of nucleobase-containing compound transport (GO:0032239)2.43639673
149positive regulation by host of viral transcription (GO:0043923)2.42938833
150mesodermal cell differentiation (GO:0048333)2.42898813
151anatomical structure regression (GO:0060033)2.42706411
152embryonic hindlimb morphogenesis (GO:0035116)2.42354987
153Arp2/3 complex-mediated actin nucleation (GO:0034314)2.41931931
154histone H3-K4 methylation (GO:0051568)2.41434771
155response to interferon-beta (GO:0035456)2.40834512
156respiratory electron transport chain (GO:0022904)2.40687924
157heme metabolic process (GO:0042168)2.40593433
158cyclooxygenase pathway (GO:0019371)2.39981765
159positive regulation of monocyte chemotaxis (GO:0090026)2.39569422
160mitochondrial electron transport, NADH to ubiquinone (GO:0006120)2.37887590
161positive regulation of neuroblast proliferation (GO:0002052)2.37425711
162NADH metabolic process (GO:0006734)2.36668445
163electron transport chain (GO:0022900)2.36073435
164cellular metabolic compound salvage (GO:0043094)2.35980214
165regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.35232872
166mesenchymal cell development (GO:0014031)2.34555970
167L-phenylalanine catabolic process (GO:0006559)2.34537991
168erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)2.34537991
169regulation of non-canonical Wnt signaling pathway (GO:2000050)2.33092898
170ceramide catabolic process (GO:0046514)2.33065661
171ventricular septum development (GO:0003281)2.32803120
172positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.32762048
173regulation of mitochondrial translation (GO:0070129)2.32697624
174negative regulation of response to reactive oxygen species (GO:1901032)2.31805616
175purine-containing compound salvage (GO:0043101)2.30941684
176regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:00432.30462210
177* regulation of cellular amino acid metabolic process (GO:0006521)2.29710989
178genitalia morphogenesis (GO:0035112)2.29656896
179cochlea morphogenesis (GO:0090103)2.29288495
180appendage morphogenesis (GO:0035107)2.29045380
181limb morphogenesis (GO:0035108)2.29045380
182substrate-independent telencephalic tangential interneuron migration (GO:0021843)2.28802863
183positive regulation of extracellular matrix organization (GO:1903055)2.27281737
184heme biosynthetic process (GO:0006783)2.23522420
185regulation of B cell apoptotic process (GO:0002902)2.23380862
186immunoglobulin mediated immune response (GO:0016064)2.23287240
187positive regulation of myeloid leukocyte cytokine production involved in immune response (GO:00610812.23112485
188energy coupled proton transport, down electrochemical gradient (GO:0015985)2.22826895
189ATP synthesis coupled proton transport (GO:0015986)2.22826895
190retrograde vesicle-mediated transport, Golgi to ER (GO:0006890)2.21549619
191regulation of superoxide metabolic process (GO:0090322)2.21422959
1922-deoxyribonucleotide metabolic process (GO:0009394)2.20690990
193tricarboxylic acid metabolic process (GO:0072350)2.19507487
194purine deoxyribonucleoside triphosphate metabolic process (GO:0009215)2.18866065
195viral transcription (GO:0019083)2.18219571
196negative regulation of inflammatory response to antigenic stimulus (GO:0002862)2.18011384
197virion attachment to host cell (GO:0019062)2.17620570
198adhesion of symbiont to host cell (GO:0044650)2.17620570
199regulation of hydrogen peroxide-induced cell death (GO:1903205)2.17536997
200mannose metabolic process (GO:0006013)2.17504870

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human4.35184323
2HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse3.86102332
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.64304366
4PPARG_19300518_ChIP-PET_3T3-L1_Mouse3.04223375
5SALL1_21062744_ChIP-ChIP_HESCs_Human2.90864560
6TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat2.86727819
7CEBPD_23245923_ChIP-Seq_MEFs_Mouse2.85909683
8EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.75371884
9GLI1_17442700_ChIP-ChIP_MESCs_Mouse2.53216150
10NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human2.49119589
11RARG_19884340_ChIP-ChIP_MEFs_Mouse2.48731549
12GBX2_23144817_ChIP-Seq_PC3_Human2.41840774
13TP63_17297297_ChIP-ChIP_HaCaT_Human2.34723879
14VDR_21846776_ChIP-Seq_THP-1_Human2.32846426
15ZNF263_19887448_ChIP-Seq_K562_Human2.26413683
16JARID1A_20064375_ChIP-Seq_MESCs_Mouse2.25436318
17POU3F2_20337985_ChIP-ChIP_501MEL_Human2.19875270
18LXR_22292898_ChIP-Seq_THP-1_Human2.19777446
19BP1_19119308_ChIP-ChIP_Hs578T_Human2.16992875
20FUS_26573619_Chip-Seq_HEK293_Human2.08276759
21TP63_19390658_ChIP-ChIP_HaCaT_Human2.03557909
22AR_21572438_ChIP-Seq_LNCaP_Human2.00295144
23TAF15_26573619_Chip-Seq_HEK293_Human1.99866724
24TCF4_18268006_ChIP-ChIP_LS174T_Human1.95047158
25IRF8_22096565_ChIP-ChIP_GC-B_Human1.93970949
26SMAD_19615063_ChIP-ChIP_OVARY_Human1.92312930
27CDX2_19796622_ChIP-Seq_MESCs_Mouse1.89299872
28ELK3_25401928_ChIP-Seq_HUVEC_Human1.88584313
29AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.87729901
30MYC_18358816_ChIP-ChIP_MESCs_Mouse1.87309061
31PIAS1_25552417_ChIP-Seq_VCAP_Human1.87024276
32HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.84689422
33TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.84398847
34ZNF217_24962896_ChIP-Seq_MCF-7_Human1.83505005
35CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.83473622
36NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.83153942
37P300_19829295_ChIP-Seq_ESCs_Human1.80995698
38PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.80134634
39EWS_26573619_Chip-Seq_HEK293_Human1.78979289
40ESR1_17901129_ChIP-ChIP_LIVER_Mouse1.77465976
41ZFP57_27257070_Chip-Seq_ESCs_Mouse1.77205678
42RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.76931670
43SMAD4_21799915_ChIP-Seq_A2780_Human1.74991452
44SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.74083073
45ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.73368379
46RACK7_27058665_Chip-Seq_MCF-7_Human1.71165673
47IGF1R_20145208_ChIP-Seq_DFB_Human1.65044637
48CEBPB_24764292_ChIP-Seq_MC3T3_Mouse1.64557847
49TP53_16413492_ChIP-PET_HCT116_Human1.63607674
50CTBP2_25329375_ChIP-Seq_LNCAP_Human1.62204133
51ELF1_17652178_ChIP-ChIP_JURKAT_Human1.61051903
52ELF1_20517297_ChIP-Seq_JURKAT_Human1.60822411
53GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.57829927
54BCAT_22108803_ChIP-Seq_LS180_Human1.57321123
55MYC_18555785_ChIP-Seq_MESCs_Mouse1.57282448
56FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.57196066
57TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.57010870
58TET1_21451524_ChIP-Seq_MESCs_Mouse1.55198750
59VDR_24763502_ChIP-Seq_THP-1_Human1.52693193
60TRIM28_21343339_ChIP-Seq_HEK293_Human1.52482167
61DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.52054838
62SRF_21415370_ChIP-Seq_HL-1_Mouse1.51630267
63* SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.49855856
64STAT3_23295773_ChIP-Seq_U87_Human1.46644495
65JARID2_20064375_ChIP-Seq_MESCs_Mouse1.46408538
66TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.46381093
67THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.45722510
68WT1_19549856_ChIP-ChIP_CCG9911_Human1.45180859
69OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.43615263
70EP300_21415370_ChIP-Seq_HL-1_Mouse1.43260202
71TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.42412738
72ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.42226901
73ETS1_20019798_ChIP-Seq_JURKAT_Human1.41273608
74BCL6_27268052_Chip-Seq_Bcells_Human1.40612994
75HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.40574413
76SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.40453884
77CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.40247818
78P68_20966046_ChIP-Seq_HELA_Human1.39094358
79EZH2_27304074_Chip-Seq_ESCs_Mouse1.39017419
80CEBPA_23403033_ChIP-Seq_LIVER_Mouse1.38570358
81PDX1_19855005_ChIP-ChIP_MIN6_Mouse1.38527850
82SMAD3_21741376_ChIP-Seq_EPCs_Human1.38511325
83FOXM1_26456572_ChIP-Seq_MCF-7_Human1.38483887
84ZNF274_21170338_ChIP-Seq_K562_Hela1.38118370
85TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.37604219
86SRY_22984422_ChIP-ChIP_TESTIS_Rat1.35794377
87RXR_22158963_ChIP-Seq_LIVER_Mouse1.34413023
88NANOG_18555785_Chip-Seq_ESCs_Mouse1.34087131
89PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.34015181
90RXR_22108803_ChIP-Seq_LS180_Human1.33802613
91BCOR_27268052_Chip-Seq_Bcells_Human1.33411882
92NR3C1_21868756_ChIP-Seq_MCF10A_Human1.32964787
93PPARA_22158963_ChIP-Seq_LIVER_Mouse1.32661634
94EGR1_19374776_ChIP-ChIP_THP-1_Human1.32523301
95TP53_18474530_ChIP-ChIP_U2OS_Human1.31920481
96ESR2_21235772_ChIP-Seq_MCF-7_Human1.31672789
97NCOR1_26117541_ChIP-Seq_K562_Human1.31208802
98AHR_22903824_ChIP-Seq_MCF-7_Human1.30666221
99KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.29829057
100CTBP1_25329375_ChIP-Seq_LNCAP_Human1.29743327
101CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.29581773
102SA1_27219007_Chip-Seq_ERYTHROID_Human1.29045868
103FOXM1_23109430_ChIP-Seq_U2OS_Human1.27855110
104TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.27166774
105ARNT_22903824_ChIP-Seq_MCF-7_Human1.27005322
106FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.26331612
107ISL1_27105846_Chip-Seq_CPCs_Mouse1.26253359
108CBX2_27304074_Chip-Seq_ESCs_Mouse1.25657828
109TOP2B_26459242_ChIP-Seq_MCF-7_Human1.25479694
110CTCF_18555785_ChIP-Seq_MESCs_Mouse1.25099129
111MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.25083928
112E2F1_18555785_Chip-Seq_ESCs_Mouse1.24990531
113SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.24974705
114SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.24836932
115EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.24814184
116FLI1_27457419_Chip-Seq_LIVER_Mouse1.24802492
117SCL_19346495_ChIP-Seq_HPC-7_Human1.24195048
118MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.24005309
119* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.23305554
120CTCF_26484167_Chip-Seq_Bcells_Mouse1.23062741
121TCF4_23295773_ChIP-Seq_U87_Human1.22583620
122TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21987101
123POU5F1_26923725_Chip-Seq_MESODERM_Mouse1.21987101
124SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.21186336
125CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.21081417
126AR_25329375_ChIP-Seq_VCAP_Human1.20960011
127CTCF_27219007_Chip-Seq_ERYTHROID_Human1.20820891
128CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse1.20641170
129STAT3_1855785_ChIP-Seq_MESCs_Mouse1.20573177
130SUZ12_27294783_Chip-Seq_NPCs_Mouse1.20069948
131HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.19699462
132MYC_22102868_ChIP-Seq_BL_Human1.19626316
133TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.19579554
134XRN2_22483619_ChIP-Seq_HELA_Human1.19297842
135RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.19095914
136MECOM_23826213_ChIP-Seq_KASUMI_Mouse1.19010045
137DCP1A_22483619_ChIP-Seq_HELA_Human1.18908086
138GATA1_22383799_ChIP-Seq_G1ME_Mouse1.18651285
139KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.18253795
140TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.17932418
141SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.17698751
142STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.17565866
143GABP_19822575_ChIP-Seq_HepG2_Human1.16515447
144ESR1_20079471_ChIP-ChIP_T-47D_Human1.16491967
145TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.14712314
146NRF2_20460467_ChIP-Seq_MEFs_Mouse1.14579317
147NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.14579317
148RNF2_27304074_Chip-Seq_ESCs_Mouse1.14539223
149PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.14187597
150EZH2_27294783_Chip-Seq_NPCs_Mouse1.14157598
151* KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.13626215
152RUNX1_22412390_ChIP-Seq_EML_Mouse1.13425063
153SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.13299161
154SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.13121892
155EZH2_18974828_ChIP-Seq_MESCs_Mouse1.12913962
156RNF2_18974828_ChIP-Seq_MESCs_Mouse1.12913962
157ATF3_27146783_Chip-Seq_COLON_Human1.12557748
158RNF2_27304074_Chip-Seq_NSC_Mouse1.12352718
159CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.12154146
160ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.11649937
161* SPI1_23127762_ChIP-Seq_K562_Human1.10876540
162NFE2_27457419_Chip-Seq_LIVER_Mouse1.10637943
163STAT4_19710469_ChIP-ChIP_TH1__Mouse1.09822339
164EED_16625203_ChIP-ChIP_MESCs_Mouse1.09489044
165SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.09271687
166GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.09259896
167* SPI1_23547873_ChIP-Seq_NB4_Human1.08688009
168FOXP3_17237761_ChIP-ChIP_TREG_Mouse1.08522319
169TFEB_21752829_ChIP-Seq_HELA_Human1.08349243
170SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.08318697
171SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.08241941
172UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human1.08131245
173MYC_19030024_ChIP-ChIP_MESCs_Mouse1.07903945
174RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.07846481
175YAP1_20516196_ChIP-Seq_MESCs_Mouse1.07454435
176LMO2_20887958_ChIP-Seq_HPC-7_Mouse1.07029139
177SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.06934300
178BMI1_23680149_ChIP-Seq_NPCS_Mouse1.06656053
179FOXA2_19822575_ChIP-Seq_HepG2_Human1.06581823
180E2F1_20622854_ChIP-Seq_HELA_Human1.06539723
181BRD4_27068464_Chip-Seq_AML-cells_Mouse1.05723965
182* ATF3_23680149_ChIP-Seq_GBM1-GSC_Human1.05628652
183RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.05491048
184P53_22387025_ChIP-Seq_ESCs_Mouse1.04649650
185BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.04297553
186CTNNB1_20460455_ChIP-Seq_HCT116_Human1.04188679
187MAF_26560356_Chip-Seq_TH2_Human1.03848085
188PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.03365873
189THAP11_20581084_ChIP-Seq_MESCs_Mouse1.03199816
190MAF_26560356_Chip-Seq_TH1_Human1.03063166
191CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.03030179
192UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.02883162
193CMYC_18555785_Chip-Seq_ESCs_Mouse1.01444732
194ER_23166858_ChIP-Seq_MCF-7_Human1.01423208
195PCGF2_27294783_Chip-Seq_ESCs_Mouse1.00489314
196* SMC4_20622854_ChIP-Seq_HELA_Human1.00418349
197LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.98826451
198STAT6_21828071_ChIP-Seq_BEAS2B_Human0.98073751

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0005058_abnormal_lysosome_morphology4.47949915
2MP0003806_abnormal_nucleotide_metabolis4.33474924
3MP0000569_abnormal_digit_pigmentation3.26989823
4MP0008438_abnormal_cutaneous_collagen3.25587638
5MP0009250_abnormal_appendicular_skeleto3.05894114
6MP0010368_abnormal_lymphatic_system2.99383480
7MP0003121_genomic_imprinting2.95182608
8MP0009697_abnormal_copulation2.94413645
9MP0009840_abnormal_foam_cell2.75880889
10MP0003787_abnormal_imprinting2.70363723
11MP0003191_abnormal_cellular_cholesterol2.57522716
12MP0000566_synostosis2.56436087
13MP0005248_abnormal_Harderian_gland2.53753605
14MP0003937_abnormal_limbs/digits/tail_de2.50632409
15MP0005397_hematopoietic_system_phenotyp2.48364802
16MP0001545_abnormal_hematopoietic_system2.48364802
17MP0009278_abnormal_bone_marrow2.48000773
18MP0003385_abnormal_body_wall2.40809225
19MP0009053_abnormal_anal_canal2.38652330
20MP0005451_abnormal_body_composition2.36983364
21MP0003122_maternal_imprinting2.35814132
22MP0005409_darkened_coat_color2.27644774
23MP0003172_abnormal_lysosome_physiology2.25352895
24MP0005464_abnormal_platelet_physiology2.17773014
25MP0003075_altered_response_to2.16689860
26MP0002148_abnormal_hypersensitivity_rea2.16358380
27MP0001853_heart_inflammation2.07468195
28MP0003718_maternal_effect2.06296805
29MP0000579_abnormal_nail_morphology2.02195207
30MP0003890_abnormal_embryonic-extraembry2.01746452
31MP0003186_abnormal_redox_activity2.00280780
32MP0005365_abnormal_bile_salt1.97959669
33MP0003436_decreased_susceptibility_to1.94981741
34MP0009384_cardiac_valve_regurgitation1.92671634
35MP0002139_abnormal_hepatobiliary_system1.85899754
36MP0003935_abnormal_craniofacial_develop1.84932688
37MP0003252_abnormal_bile_duct1.82932831
38MP0006276_abnormal_autonomic_nervous1.82664937
39MP0003755_abnormal_palate_morphology1.81940565
40MP0000343_altered_response_to1.81848669
41MP0003279_aneurysm1.74362308
42MP0000733_abnormal_muscle_development1.73169883
43MP0000383_abnormal_hair_follicle1.72485841
44MP0010678_abnormal_skin_adnexa1.71979250
45MP0000858_altered_metastatic_potential1.66587617
46MP0006082_CNS_inflammation1.65666637
47MP0002938_white_spotting1.64552924
48MP0008877_abnormal_DNA_methylation1.64364065
49MP0001542_abnormal_bone_strength1.63165380
50MP0005076_abnormal_cell_differentiation1.62350706
51MP0001835_abnormal_antigen_presentation1.62200298
52MP0001293_anophthalmia1.62180583
53MP0002419_abnormal_innate_immunity1.61316802
54MP0006036_abnormal_mitochondrial_physio1.56644306
55MP0004272_abnormal_basement_membrane1.56187338
56MP0000678_abnormal_parathyroid_gland1.55927044
57MP0005503_abnormal_tendon_morphology1.55542645
58MP0008057_abnormal_DNA_replication1.53176662
59MP0008260_abnormal_autophagy1.52634247
60MP0009785_altered_susceptibility_to1.52155597
61MP0002233_abnormal_nose_morphology1.51404020
62MP0005025_abnormal_response_to1.50612051
63MP0006292_abnormal_olfactory_placode1.49566269
64MP0000432_abnormal_head_morphology1.49529791
65MP0001188_hyperpigmentation1.48682246
66MP0005165_increased_susceptibility_to1.47398766
67MP0002009_preneoplasia1.47207458
68MP0002249_abnormal_larynx_morphology1.45781307
69MP0005023_abnormal_wound_healing1.42698108
70MP0001958_emphysema1.42354882
71MP0005360_urolithiasis1.41381102
72MP0001533_abnormal_skeleton_physiology1.40971216
73MP0008469_abnormal_protein_level1.40642225
74MP0005395_other_phenotype1.39570014
75MP0003123_paternal_imprinting1.37667033
76MP0002132_abnormal_respiratory_system1.37580551
77MP0005085_abnormal_gallbladder_physiolo1.37166871
78MP0001286_abnormal_eye_development1.36818359
79MP0001879_abnormal_lymphatic_vessel1.36546133
80MP0009703_decreased_birth_body1.35266194
81MP0000681_abnormal_thyroid_gland1.35201602
82MP0001299_abnormal_eye_distance/1.34850491
83MP0005171_absent_coat_pigmentation1.33729699
84MP0000462_abnormal_digestive_system1.32978204
85MP0009333_abnormal_splenocyte_physiolog1.28724955
86MP0002932_abnormal_joint_morphology1.28574554
87MP0009764_decreased_sensitivity_to1.27953035
88MP0001881_abnormal_mammary_gland1.27545553
89MP0004381_abnormal_hair_follicle1.26293734
90MP0005000_abnormal_immune_tolerance1.25753526
91MP0003303_peritoneal_inflammation1.25590892
92MP0003942_abnormal_urinary_system1.25406510
93MP0002177_abnormal_outer_ear1.23854368
94MP0004947_skin_inflammation1.23636413
95MP0002060_abnormal_skin_morphology1.22885014
96MP0009672_abnormal_birth_weight1.22174414
97MP0001764_abnormal_homeostasis1.21395961
98MP0002282_abnormal_trachea_morphology1.21065964
99MP0005187_abnormal_penis_morphology1.21018417
100MP0001661_extended_life_span1.20651197
101MP0003566_abnormal_cell_adhesion1.19469545
102MP0000049_abnormal_middle_ear1.18758261
103MP0002109_abnormal_limb_morphology1.18464121
104MP0001340_abnormal_eyelid_morphology1.18088380
105MP0003567_abnormal_fetal_cardiomyocyte1.17900657
106MP0005166_decreased_susceptibility_to1.17325344
107MP0001346_abnormal_lacrimal_gland1.16824385
108MP0000427_abnormal_hair_cycle1.16494560
109MP0004264_abnormal_extraembryonic_tissu1.15984710
110MP0003868_abnormal_feces_composition1.15652817
111MP0000516_abnormal_urinary_system1.14708265
112MP0005367_renal/urinary_system_phenotyp1.14708265
113MP0005319_abnormal_enzyme/_coenzyme1.13948877
114MP0004858_abnormal_nervous_system1.13700940
115MP0000604_amyloidosis1.11256984
116MP0002116_abnormal_craniofacial_bone1.09185708
117MP0002098_abnormal_vibrissa_morphology1.07863061
118MP0002084_abnormal_developmental_patter1.07673364
119MP0005390_skeleton_phenotype1.06116457
120MP0002452_abnormal_antigen_presenting1.04153162
121MP0002877_abnormal_melanocyte_morpholog1.03510879
122MP0005275_abnormal_skin_tensile1.03455441
123MP0002925_abnormal_cardiovascular_devel1.03139356
124MP0005164_abnormal_response_to1.02676441
125MP0004808_abnormal_hematopoietic_stem1.02365871
126MP0001845_abnormal_inflammatory_respons1.02102017
127MP0008007_abnormal_cellular_replicative1.01713104
128MP0005584_abnormal_enzyme/coenzyme_acti1.01592944
129MP0003453_abnormal_keratinocyte_physiol1.00073951
130MP0000163_abnormal_cartilage_morphology0.99297698
131MP0003941_abnormal_skin_development0.98629032
132MP0001243_abnormal_dermal_layer0.96547761
133MP0005501_abnormal_skin_physiology0.96488283
134MP0002723_abnormal_immune_serum0.95864779
135MP0005623_abnormal_meninges_morphology0.95299565
136MP0009643_abnormal_urine_homeostasis0.93531352
137MP0003656_abnormal_erythrocyte_physiolo0.93333450
138MP0000639_abnormal_adrenal_gland0.92685900
139MP0002085_abnormal_embryonic_tissue0.91882888
140MP0003786_premature_aging0.91278218
141MP0006054_spinal_hemorrhage0.90882887
142MP0005330_cardiomyopathy0.90217680
143MP0001873_stomach_inflammation0.89495803
144MP0000685_abnormal_immune_system0.89307701
145MP0000534_abnormal_ureter_morphology0.89281724
146MP0006138_congestive_heart_failure0.88467922
147MP0000647_abnormal_sebaceous_gland0.88154509
148MP0005380_embryogenesis_phenotype0.87924936
149MP0001672_abnormal_embryogenesis/_devel0.87924936
150MP0010234_abnormal_vibrissa_follicle0.87368299
151MP0003448_altered_tumor_morphology0.86465478
152MP0002168_other_aberrant_phenotype0.86335179
153MP0003861_abnormal_nervous_system0.86302754
154MP0003984_embryonic_growth_retardation0.85842231
155MP0002088_abnormal_embryonic_growth/wei0.85801671
156MP0005332_abnormal_amino_acid0.83973261
157MP0000358_abnormal_cell_content/0.82995344
158MP0000762_abnormal_tongue_morphology0.82786027
159MP0003115_abnormal_respiratory_system0.82615828
160MP0001819_abnormal_immune_cell0.82263748
161MP0002420_abnormal_adaptive_immunity0.82102365
162MP0004782_abnormal_surfactant_physiolog0.82013118
163MP0003795_abnormal_bone_structure0.81503935
164MP0002092_abnormal_eye_morphology0.81357082
165MP0002115_abnormal_skeleton_extremities0.81098070
166MP0009763_increased_sensitivity_to0.80957395
167MP0000609_abnormal_liver_physiology0.80121293
168MP0005508_abnormal_skeleton_morphology0.79772528
169MP0003950_abnormal_plasma_membrane0.79068760
170MP0000428_abnormal_craniofacial_morphol0.78867627
171MP0000750_abnormal_muscle_regeneration0.78596869
172MP0000465_gastrointestinal_hemorrhage0.78209986
173MP0005636_abnormal_mineral_homeostasis0.77562114
174MP0003045_fibrosis0.77079721
175MP0004233_abnormal_muscle_weight0.76495928
176MP0000377_abnormal_hair_follicle0.75954006
177MP0002108_abnormal_muscle_morphology0.75303070
178MP0003705_abnormal_hypodermis_morpholog0.75006296
179MP0010155_abnormal_intestine_physiology0.74466487
180MP0010630_abnormal_cardiac_muscle0.74389037
181MP0005646_abnormal_pituitary_gland0.74313747
182MP0003638_abnormal_response/metabolism_0.74114329
183MP0002405_respiratory_system_inflammati0.73834998
184* MP0008875_abnormal_xenobiotic_pharmacok0.73800503
185MP0000266_abnormal_heart_morphology0.73457658
186MP0001216_abnormal_epidermal_layer0.73309961
187MP0009931_abnormal_skin_appearance0.72950738
188MP0005410_abnormal_fertilization0.72692706
189MP0001790_abnormal_immune_system0.72165454
190MP0005387_immune_system_phenotype0.72165454
191MP0002295_abnormal_pulmonary_circulatio0.71476251

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of glycolipid metabolism (HP:0010969)4.86135433
2Abnormality of liposaccharide metabolism (HP:0010968)4.86135433
3Abnormality of glycosphingolipid metabolism (HP:0004343)4.86135433
4Short 4th metacarpal (HP:0010044)4.74391697
5Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)4.74391697
6Cortical dysplasia (HP:0002539)4.51705013
7Papillary thyroid carcinoma (HP:0002895)3.93158780
8Volvulus (HP:0002580)3.91677304
9Coronal craniosynostosis (HP:0004440)3.78158586
10Chorioretinal atrophy (HP:0000533)3.75266130
11Increased number of teeth (HP:0011069)3.72849180
12Petechiae (HP:0000967)3.69376998
13Dysostosis multiplex (HP:0000943)3.64381899
14Vertebral compression fractures (HP:0002953)3.52392713
15Narrow palate (HP:0000189)3.50232242
16Long eyelashes (HP:0000527)3.46524599
17Abnormality of the 4th metacarpal (HP:0010012)3.43074357
18Abnormality of incisor morphology (HP:0011063)3.34884501
19Genetic anticipation (HP:0003743)3.33517482
20Abnormality of the nasal septum (HP:0000419)3.31117788
21Midline defect of the nose (HP:0004122)3.27173805
22Vacuolated lymphocytes (HP:0001922)3.18878355
23Abnormal mitochondria in muscle tissue (HP:0008316)3.18106814
24Abnormality of the phalanges of the hallux (HP:0010057)3.12518242
25Abnormality of the parietal bone (HP:0002696)3.11325839
26Rectal prolapse (HP:0002035)3.08623667
27Urethral obstruction (HP:0000796)3.08360167
28Systemic lupus erythematosus (HP:0002725)2.94632843
29Cutaneous finger syndactyly (HP:0010554)2.91786102
30Abnormality of the fingertips (HP:0001211)2.89092950
31Purpura (HP:0000979)2.88923304
32Microglossia (HP:0000171)2.87613269
33Premature rupture of membranes (HP:0001788)2.81225308
34Acute necrotizing encephalopathy (HP:0006965)2.80850214
35Partial duplication of the phalanx of hand (HP:0009999)2.79449211
36Lymphangioma (HP:0100764)2.77520102
37Abnormality of mucopolysaccharide metabolism (HP:0011020)2.76722117
38Abnormality of polysaccharide metabolism (HP:0011012)2.76722117
39Abnormality of glycosaminoglycan metabolism (HP:0004371)2.76722117
40Rhabdomyosarcoma (HP:0002859)2.76264007
41Urinary glycosaminoglycan excretion (HP:0003541)2.72727500
42Mucopolysacchariduria (HP:0008155)2.72727500
43Type I transferrin isoform profile (HP:0003642)2.71010888
44Abnormality of the right ventricle (HP:0001707)2.70193239
45J-shaped sella turcica (HP:0002680)2.68869875
46* Hypertensive crisis (HP:0100735)2.68348734
47Abnormality of aromatic amino acid family metabolism (HP:0004338)2.68076833
48Protrusio acetabuli (HP:0003179)2.66772570
49Lip pit (HP:0100267)2.65052435
50Macroorchidism (HP:0000053)2.63359267
51Aplasia cutis congenita (HP:0001057)2.57908969
52Abnormality of the phalanges of the 2nd finger (HP:0009541)2.56599816
53Abnormal gallbladder physiology (HP:0012438)2.55291933
54Cholecystitis (HP:0001082)2.55291933
55Acute encephalopathy (HP:0006846)2.54384595
56Increased cerebral lipofuscin (HP:0011813)2.52478892
57Hypochromic microcytic anemia (HP:0004840)2.52394675
58Mitochondrial inheritance (HP:0001427)2.51406079
59Increased muscle lipid content (HP:0009058)2.43582679
60Decreased activity of mitochondrial respiratory chain (HP:0008972)2.42326645
61Abnormal activity of mitochondrial respiratory chain (HP:0011922)2.42326645
62Testicular atrophy (HP:0000029)2.41360945
63Prolonged neonatal jaundice (HP:0006579)2.37440425
64Syringomyelia (HP:0003396)2.36381973
65Spinal cord lesions (HP:0100561)2.36381973
66Abnormality of abdominal situs (HP:0011620)2.36146445
67Abdominal situs inversus (HP:0003363)2.36146445
68Absent eyebrow (HP:0002223)2.35986398
69Flat face (HP:0012368)2.35578156
70Hypokinesia (HP:0002375)2.33798934
71Increased intramyocellular lipid droplets (HP:0012240)2.32753344
72Distal lower limb muscle weakness (HP:0009053)2.32619651
73Joint stiffness (HP:0001387)2.30771300
74Ragged-red muscle fibers (HP:0003200)2.29222956
75Aplasia of the musculature (HP:0100854)2.28270032
76Abnormality of the incisor (HP:0000676)2.27985146
77Increased neuronal autofluorescent lipopigment (HP:0002074)2.27604956
78Cutaneous syndactyly (HP:0012725)2.27522663
79Abnormality of the nasolacrimal system (HP:0000614)2.27358261
80Abnormality of the columella (HP:0009929)2.27246517
81Increased serum ferritin (HP:0003281)2.26523777
82Excessive salivation (HP:0003781)2.26415006
83Drooling (HP:0002307)2.26415006
84Acute myeloid leukemia (HP:0004808)2.25391756
85Thyroid carcinoma (HP:0002890)2.24489269
86Small hand (HP:0200055)2.24164661
87Hepatocellular necrosis (HP:0001404)2.23684624
88Vitreoretinal degeneration (HP:0000655)2.22609964
89Progressive macrocephaly (HP:0004481)2.22338904
90Opisthotonus (HP:0002179)2.22147949
91Hepatosplenomegaly (HP:0001433)2.19955971
92Hepatic necrosis (HP:0002605)2.19652141
93Esophageal neoplasm (HP:0100751)2.18778833
94Neoplasm of head and neck (HP:0012288)2.18778833
95Shallow orbits (HP:0000586)2.18732449
96Long nose (HP:0003189)2.18720718
97Sparse lateral eyebrow (HP:0005338)2.18618379
98Hypoplasia of the maxilla (HP:0000327)2.18489877
99Cervical subluxation (HP:0003308)2.18003978
100Oligodontia (HP:0000677)2.16996328
101Ectopic kidney (HP:0000086)2.15485322
102Polycythemia (HP:0001901)2.14532250
103Spastic paraparesis (HP:0002313)2.13709577
104Rough bone trabeculation (HP:0100670)2.13081833
105Supernumerary ribs (HP:0005815)2.12846061
106Deep philtrum (HP:0002002)2.12491652
107Axonal loss (HP:0003447)2.10837694
108Entropion (HP:0000621)2.10351572
109Increased CSF lactate (HP:0002490)2.10179952
110Facial hemangioma (HP:0000329)2.09694672
111Renal hypoplasia (HP:0000089)2.09117326
112Deep venous thrombosis (HP:0002625)2.09084937
113Nonimmune hydrops fetalis (HP:0001790)2.08581824
114Abnormal protein glycosylation (HP:0012346)2.08278761
115Abnormal glycosylation (HP:0012345)2.08278761
116Abnormal isoelectric focusing of serum transferrin (HP:0003160)2.08278761
117Abnormal protein N-linked glycosylation (HP:0012347)2.08278761
118Loss of speech (HP:0002371)2.07518438
119Neoplasm of striated muscle (HP:0009728)2.07076007
120Broad thumb (HP:0011304)2.05758870
121Transitional cell carcinoma of the bladder (HP:0006740)2.05394828
122Widely spaced teeth (HP:0000687)2.05370081
123Interstitial pulmonary disease (HP:0006530)2.05321647
124Abnormality of complement system (HP:0005339)2.04969903
125* Hyperthyroidism (HP:0000836)2.03655344
126Broad toe (HP:0001837)2.03299307
127Stridor (HP:0010307)2.02031727
128Mesangial abnormality (HP:0001966)2.01714978
129Progressive neurologic deterioration (HP:0002344)2.01592383
130Thick eyebrow (HP:0000574)1.97159592
131Chronic hepatic failure (HP:0100626)1.97067516
132Oligodactyly (HP:0012165)1.96532104
133Trismus (HP:0000211)1.95706666
134Renal Fanconi syndrome (HP:0001994)1.95605878
135Complement deficiency (HP:0004431)1.95306163
136Broad hallux (HP:0010055)1.94924034
137Abnormality of the pulmonary veins (HP:0011718)1.94650164
138Trigonocephaly (HP:0000243)1.94498879
139Bladder neoplasm (HP:0009725)1.94317243
140Bladder carcinoma (HP:0002862)1.94317243
141Thrombocytosis (HP:0001894)1.93953424
142Hypoplastic labia majora (HP:0000059)1.93793941
143Redundant skin (HP:0001582)1.93168497
144Cerebral edema (HP:0002181)1.92855005
145Impulsivity (HP:0100710)1.92073355
146Agitation (HP:0000713)1.91718186
147Elevated erythrocyte sedimentation rate (HP:0003565)1.90186795
148Achilles tendon contracture (HP:0001771)1.89965196
149Abnormal platelet function (HP:0011869)1.89522676
150Impaired platelet aggregation (HP:0003540)1.89522676
151Respiratory failure (HP:0002878)1.88851680
152Truncal obesity (HP:0001956)1.88579164
153Abnormality of dicarboxylic acid metabolism (HP:0010995)1.87644366
154Dicarboxylic aciduria (HP:0003215)1.87644366
155Downturned corners of mouth (HP:0002714)1.85224084
156Skull defect (HP:0001362)1.85152845
157* Obstructive lung disease (HP:0006536)1.84565386
158* Chronic obstructive pulmonary disease (HP:0006510)1.84565386
159Epistaxis (HP:0000421)1.83383749
160Nasolacrimal duct obstruction (HP:0000579)1.83334252
161Wide anterior fontanel (HP:0000260)1.82674275
162Reticulocytosis (HP:0001923)1.81948321
163Intellectual disability, moderate (HP:0002342)1.80174961
164Generalized amyotrophy (HP:0003700)1.79546707
165Anomalous pulmonary venous return (HP:0010772)1.79156185
166Synophrys (HP:0000664)1.79117845
167Amyloidosis (HP:0011034)1.78770867
168Mitral stenosis (HP:0001718)1.78228864
169Cardiomegaly (HP:0001640)1.77960195
170Abnormality of the Achilles tendon (HP:0005109)1.77347350
171Abnormal number of erythroid precursors (HP:0012131)1.76980801
172Supernumerary bones of the axial skeleton (HP:0009144)1.76902984
173Elbow flexion contracture (HP:0002987)1.76436167
174Abnormality of iron homeostasis (HP:0011031)1.75696902
175Exercise intolerance (HP:0003546)1.75551402
176Distal upper limb amyotrophy (HP:0007149)1.75292818
177Upper limb amyotrophy (HP:0009129)1.75292818
178Prolonged bleeding time (HP:0003010)1.74028972
179Limited elbow extension (HP:0001377)1.73080522
180Hydroureter (HP:0000072)1.72144884
181Infantile muscular hypotonia (HP:0008947)1.71783484
182Ileus (HP:0002595)1.71727640
183Low anterior hairline (HP:0000294)1.71384027
184Aplasia/Hypoplasia of metatarsal bones (HP:0001964)1.70549747
185Microtia (HP:0008551)1.70392685
186Obsessive-compulsive behavior (HP:0000722)1.70378332
187Abnormality of the labia majora (HP:0012881)1.69518785
188Hypoplastic left heart (HP:0004383)1.69170779
189Fair hair (HP:0002286)1.69120139
190Progressive muscle weakness (HP:0003323)1.69047646
191Short philtrum (HP:0000322)1.68595625
192Lactic acidosis (HP:0003128)1.68594308
193Hydronephrosis (HP:0000126)1.68537025
194Reduced subcutaneous adipose tissue (HP:0003758)1.67479793
195Spondylolisthesis (HP:0003302)1.67359791
196Smooth philtrum (HP:0000319)1.66883910
197Aplastic anemia (HP:0001915)1.66662409
198Abnormal trabecular bone morphology (HP:0100671)1.65767392
199Hyperventilation (HP:0002883)1.65066694
200Urinary bladder sphincter dysfunction (HP:0002839)1.64742219

Predicted kinase interactions (KEA)

RankGene SetZ-score
1NME24.42002071
2LATS13.42413326
3ERN13.39466643
4CDK123.21805144
5CAMK1G3.16466335
6DMPK3.15521640
7IRAK33.13418103
8TESK23.10721329
9TAOK32.96254296
10VRK22.78497879
11PIM22.74554376
12TESK12.73679395
13BCKDK2.66480588
14CAMK1D2.59137751
15PNCK2.49122040
16MAP3K62.45997559
17EPHA22.38011828
18INSRR2.19979921
19SCYL22.09454039
20ARAF2.05758957
21NLK1.99305846
22STK101.95757414
23CSNK1G11.92801654
24TBK11.92696571
25TRIB31.92543958
26MAP3K41.88670383
27MYLK1.88565248
28ABL21.85123411
29SIK31.76848710
30MAPKAPK31.71736422
31CDC71.69311703
32CSNK1A1L1.66519862
33KDR1.65959076
34BRD41.65915933
35TAOK21.64667397
36CDK61.60821549
37MAP3K31.59969566
38BCR1.59939970
39WNK11.57683543
40CASK1.57659379
41NTRK31.56789332
42MAP3K111.52509564
43PAK41.48507311
44MAP2K31.46922836
45MAP3K121.46782771
46LIMK11.45958967
47CHEK21.44415034
48FLT31.43675247
49CSNK1G31.42757357
50KIT1.42248191
51CSNK1G21.40864809
52STK31.39850175
53MKNK11.39139743
54CDK31.35550208
55SIK11.31906563
56FRK1.26958762
57EPHB21.26928051
58NUAK11.25064768
59SMG11.23884755
60MAP2K71.19849744
61MAP2K41.17939971
62ILK1.16680091
63CDK91.15997749
64TNK21.15669172
65PIK3CA1.15419879
66AKT31.10736660
67DAPK11.10673830
68PLK41.08802630
69FGFR21.06302747
70PLK21.06183231
71MTOR1.05764717
72LATS21.05635050
73RIPK41.05405182
74WNK31.05044700
75PRKAA21.05030001
76IKBKB1.03476279
77JAK31.02637936
78DAPK31.00683619
79TYK21.00510661
80RPS6KB21.00489036
81STK160.98150825
82CDK80.95870628
83MKNK20.94019480
84ZAP700.92933448
85EPHA40.92625297
86PTK20.92537431
87CLK10.92310100
88ATM0.90144075
89BMPR1B0.88527344
90CSNK1E0.87473013
91PRKD20.86398934
92EIF2AK10.86047377
93TGFBR20.82829783
94NME10.82643420
95BRAF0.82225686
96MST1R0.81380430
97BMPR20.81228120
98ERBB20.81148823
99GRK70.78871812
100PLK30.78591583
101MUSK0.78167199
102DDR20.76841579
103STK380.76822729
104NEK90.76597997
105LRRK20.76567102
106MAPK100.76334505
107CSF1R0.75169187
108MAP4K10.74293756
109PRPF4B0.74056490
110NTRK10.73360843
111CAMK2G0.70574675
112MAP3K50.69177740
113RAF10.67136509
114MATK0.66915007
115MELK0.66886124
116PBK0.66782256
117MAP2K20.65599249
118CSNK1D0.65087519
119PRKG10.63853652
120TTK0.63344253
121MOS0.63043186
122MAP2K60.62760393
123PAK10.62581067
124MAP3K10.61301373
125BLK0.60968843
126ADRBK10.60549879
127PRKCQ0.60163328
128KSR10.60032902
129RPS6KA40.59796572
130CAMK2A0.58803520
131RIPK10.57045853
132CDK10.56313910
133SGK30.56294878
134SGK10.55624372
135IRAK20.55249958
136CDC42BPA0.54645280
137CAMK10.54559969
138CDK40.54445874
139MAP3K90.53878909
140SGK20.53603161
141FGFR30.53354301
142MAPK140.52938762
143CHEK10.52721047
144MAPKAPK50.52322254
145ROCK10.51669342
146GSK3B0.51635249
147PDPK10.51124559
148GRK60.51032047
149CCNB10.50096833
150MAPK110.49969771
151FER0.49448310
152ROCK20.48524306
153MAPKAPK20.47712024
154PAK30.46887275
155MAPK10.46413692
156CSNK1A10.45684082
157IRAK10.45474974
158MET0.45183430
159NEK20.45148592
160CDK70.44521108
161TAOK10.44250437
162MAP3K20.43058370
163CDK20.42523559
164GRK50.42501865
165STK110.42296169
166STK390.41863119
167AURKA0.41788381
168PRKD10.41003598
169BTK0.39910749
170PAK20.39435988
171PIK3CG0.39397456
172ICK0.39237041
173PRKCI0.39193295
174AKT10.38787250
175PDK20.38730533
176BMX0.38566987
177MAPK80.38498261
178FGFR10.38040422
179FES0.36839259
180NTRK20.36338575
181IKBKE0.36266234
182PRKD30.36143699
183MAP3K80.32601485
184PRKG20.31809036
185MAPK150.31656859
186PDGFRA0.31347928
187CAMK2D0.30577033
188LMTK20.30159218
189RPS6KA50.29432768
190TTN0.29360120

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009105.25241221
2Other glycan degradation_Homo sapiens_hsa005114.69047046
3Proteasome_Homo sapiens_hsa030503.42943942
4Glycosaminoglycan degradation_Homo sapiens_hsa005313.07626958
5Ribosome_Homo sapiens_hsa030102.47444783
6Oxidative phosphorylation_Homo sapiens_hsa001902.39247079
7Lysosome_Homo sapiens_hsa041422.35524099
8Primary bile acid biosynthesis_Homo sapiens_hsa001202.26384948
9Dorso-ventral axis formation_Homo sapiens_hsa043202.25573384
10Arginine biosynthesis_Homo sapiens_hsa002202.10022340
11Lysine degradation_Homo sapiens_hsa003102.04946600
12Sulfur relay system_Homo sapiens_hsa041221.98449517
13Glutathione metabolism_Homo sapiens_hsa004801.96539317
14Adherens junction_Homo sapiens_hsa045201.94504023
15Pentose phosphate pathway_Homo sapiens_hsa000301.93305473
16Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.90904095
17Cyanoamino acid metabolism_Homo sapiens_hsa004601.78476038
18Parkinsons disease_Homo sapiens_hsa050121.77219363
192-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.77118212
20Fructose and mannose metabolism_Homo sapiens_hsa000511.75222784
21Complement and coagulation cascades_Homo sapiens_hsa046101.74235758
22Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005321.72832295
23MicroRNAs in cancer_Homo sapiens_hsa052061.70581621
24Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005201.70518179
25TGF-beta signaling pathway_Homo sapiens_hsa043501.70418169
26Fatty acid elongation_Homo sapiens_hsa000621.68996531
27Axon guidance_Homo sapiens_hsa043601.60928026
28Rheumatoid arthritis_Homo sapiens_hsa053231.57730091
29Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049321.57022985
30Prostate cancer_Homo sapiens_hsa052151.56750026
31Basal cell carcinoma_Homo sapiens_hsa052171.54687621
32Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.48862336
33Wnt signaling pathway_Homo sapiens_hsa043101.48653623
34Tryptophan metabolism_Homo sapiens_hsa003801.46926339
35Renal cell carcinoma_Homo sapiens_hsa052111.45109528
36N-Glycan biosynthesis_Homo sapiens_hsa005101.42953613
37Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005341.41840831
38Galactose metabolism_Homo sapiens_hsa000521.40518633
39Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008601.39358457
40Asthma_Homo sapiens_hsa053101.38342011
41SNARE interactions in vesicular transport_Homo sapiens_hsa041301.37393872
42Base excision repair_Homo sapiens_hsa034101.36403982
43Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.33938308
44Drug metabolism - other enzymes_Homo sapiens_hsa009831.33564171
45DNA replication_Homo sapiens_hsa030301.32788444
46Ovarian steroidogenesis_Homo sapiens_hsa049131.32566871
47Carbon metabolism_Homo sapiens_hsa012001.31124302
48Ascorbate and aldarate metabolism_Homo sapiens_hsa000531.31041082
49Non-homologous end-joining_Homo sapiens_hsa034501.30317866
50Alzheimers disease_Homo sapiens_hsa050101.27799271
51Thyroid cancer_Homo sapiens_hsa052161.27626551
52Hippo signaling pathway_Homo sapiens_hsa043901.26451952
53Vibrio cholerae infection_Homo sapiens_hsa051101.25659761
54Pyrimidine metabolism_Homo sapiens_hsa002401.24895970
55Biosynthesis of amino acids_Homo sapiens_hsa012301.21595673
56Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.21229090
57Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.18376967
58Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.18108580
59Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005631.17315319
60Serotonergic synapse_Homo sapiens_hsa047261.16300656
61Melanogenesis_Homo sapiens_hsa049161.15931057
62Colorectal cancer_Homo sapiens_hsa052101.15301960
63Glycine, serine and threonine metabolism_Homo sapiens_hsa002601.15152587
64Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010401.11678375
65Phenylalanine metabolism_Homo sapiens_hsa003601.11639187
66Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.11261727
67Hedgehog signaling pathway_Homo sapiens_hsa043401.09607371
68Cell cycle_Homo sapiens_hsa041101.07373815
69Huntingtons disease_Homo sapiens_hsa050161.07217159
70Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.06865406
71Pertussis_Homo sapiens_hsa051331.05655577
72Proteoglycans in cancer_Homo sapiens_hsa052051.04129300
73Shigellosis_Homo sapiens_hsa051311.03833512
74Leishmaniasis_Homo sapiens_hsa051401.01690550
75Folate biosynthesis_Homo sapiens_hsa007901.01429890
76One carbon pool by folate_Homo sapiens_hsa006701.01132873
77Nicotine addiction_Homo sapiens_hsa050330.99434361
78cAMP signaling pathway_Homo sapiens_hsa040240.98744008
79Steroid biosynthesis_Homo sapiens_hsa001000.98464607
80Intestinal immune network for IgA production_Homo sapiens_hsa046720.97662142
81Salmonella infection_Homo sapiens_hsa051320.96663358
82Allograft rejection_Homo sapiens_hsa053300.94523814
83FoxO signaling pathway_Homo sapiens_hsa040680.94201795
84Pancreatic cancer_Homo sapiens_hsa052120.93584246
85Prion diseases_Homo sapiens_hsa050200.93311549
86Antigen processing and presentation_Homo sapiens_hsa046120.92712772
87Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.91904383
88Choline metabolism in cancer_Homo sapiens_hsa052310.91557085
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.90816087
90Bile secretion_Homo sapiens_hsa049760.90566547
91Long-term depression_Homo sapiens_hsa047300.89081403
92Dilated cardiomyopathy_Homo sapiens_hsa054140.87076397
93Amphetamine addiction_Homo sapiens_hsa050310.86279400
94Long-term potentiation_Homo sapiens_hsa047200.86185654
95Bladder cancer_Homo sapiens_hsa052190.84630585
96Phagosome_Homo sapiens_hsa041450.83662064
97Glioma_Homo sapiens_hsa052140.83655735
98Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.82912267
99Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.82785843
100Aldosterone synthesis and secretion_Homo sapiens_hsa049250.82647274
101Thyroid hormone signaling pathway_Homo sapiens_hsa049190.82551886
102Renin secretion_Homo sapiens_hsa049240.80945972
103Collecting duct acid secretion_Homo sapiens_hsa049660.80508649
104Cocaine addiction_Homo sapiens_hsa050300.80373154
105Toll-like receptor signaling pathway_Homo sapiens_hsa046200.80370681
106Endometrial cancer_Homo sapiens_hsa052130.80117754
107Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.79999074
108Chemical carcinogenesis_Homo sapiens_hsa052040.79947884
109cGMP-PKG signaling pathway_Homo sapiens_hsa040220.78639900
110Transcriptional misregulation in cancer_Homo sapiens_hsa052020.77338014
111* Steroid hormone biosynthesis_Homo sapiens_hsa001400.76594360
112Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.76527826
113Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.76182830
114Circadian rhythm_Homo sapiens_hsa047100.75020172
115* Tyrosine metabolism_Homo sapiens_hsa003500.74816902
116Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.74740184
117Peroxisome_Homo sapiens_hsa041460.74398684
118Graft-versus-host disease_Homo sapiens_hsa053320.74043435
119Butanoate metabolism_Homo sapiens_hsa006500.73963641
120Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.73586632
121Melanoma_Homo sapiens_hsa052180.72960054
122Tuberculosis_Homo sapiens_hsa051520.72732435
123Histidine metabolism_Homo sapiens_hsa003400.71993266
124RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.71251244
125Pathways in cancer_Homo sapiens_hsa052000.70939227
126Glucagon signaling pathway_Homo sapiens_hsa049220.70521538
127Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.68543804
128Acute myeloid leukemia_Homo sapiens_hsa052210.68458189
129Viral myocarditis_Homo sapiens_hsa054160.66796212
130Type II diabetes mellitus_Homo sapiens_hsa049300.66468071
131Nucleotide excision repair_Homo sapiens_hsa034200.66431411
132Ether lipid metabolism_Homo sapiens_hsa005650.66420610
133Oxytocin signaling pathway_Homo sapiens_hsa049210.66255536
134* Metabolic pathways_Homo sapiens_hsa011000.65774123
135Regulation of actin cytoskeleton_Homo sapiens_hsa048100.65727645
136Malaria_Homo sapiens_hsa051440.64531598
137Insulin secretion_Homo sapiens_hsa049110.64439338
138Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.64272379
139Fatty acid metabolism_Homo sapiens_hsa012120.64050968
140Focal adhesion_Homo sapiens_hsa045100.63962417
141Arachidonic acid metabolism_Homo sapiens_hsa005900.63942948
142Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.63731881
143Ras signaling pathway_Homo sapiens_hsa040140.63404146
144MAPK signaling pathway_Homo sapiens_hsa040100.62912286
145Autoimmune thyroid disease_Homo sapiens_hsa053200.61937528
146Oocyte meiosis_Homo sapiens_hsa041140.61342781
147RNA polymerase_Homo sapiens_hsa030200.61326710
148ErbB signaling pathway_Homo sapiens_hsa040120.60516693
149Pyruvate metabolism_Homo sapiens_hsa006200.60488414
150Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.60093557
151Small cell lung cancer_Homo sapiens_hsa052220.59359283
152Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.59015205
153Vascular smooth muscle contraction_Homo sapiens_hsa042700.58520824
154Sphingolipid metabolism_Homo sapiens_hsa006000.57101272
155Glutamatergic synapse_Homo sapiens_hsa047240.56450115
156Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.56303651
157Toxoplasmosis_Homo sapiens_hsa051450.56123754
158* Dopaminergic synapse_Homo sapiens_hsa047280.55619541
159Staphylococcus aureus infection_Homo sapiens_hsa051500.55444191
160mTOR signaling pathway_Homo sapiens_hsa041500.54364555
161Caffeine metabolism_Homo sapiens_hsa002320.53962520
162Rap1 signaling pathway_Homo sapiens_hsa040150.53766736
163GABAergic synapse_Homo sapiens_hsa047270.53351217
164Salivary secretion_Homo sapiens_hsa049700.52628059
165Longevity regulating pathway - mammal_Homo sapiens_hsa042110.52356710
166Gap junction_Homo sapiens_hsa045400.50467003
167Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.49302663
168Platelet activation_Homo sapiens_hsa046110.49125528
169Legionellosis_Homo sapiens_hsa051340.48511585
170Mismatch repair_Homo sapiens_hsa034300.48104148
171Leukocyte transendothelial migration_Homo sapiens_hsa046700.47815953
172Hematopoietic cell lineage_Homo sapiens_hsa046400.47746752
173Tight junction_Homo sapiens_hsa045300.46438259
174Insulin resistance_Homo sapiens_hsa049310.45870858
175p53 signaling pathway_Homo sapiens_hsa041150.45295197
176Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.45000193
177Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.44379820
178Sulfur metabolism_Homo sapiens_hsa009200.44101322
179Pentose and glucuronate interconversions_Homo sapiens_hsa000400.44079626
180Osteoclast differentiation_Homo sapiens_hsa043800.43294431
181Cysteine and methionine metabolism_Homo sapiens_hsa002700.43225005
182Influenza A_Homo sapiens_hsa051640.42069240
183Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.42023482
184Apoptosis_Homo sapiens_hsa042100.41316656
185TNF signaling pathway_Homo sapiens_hsa046680.41166865
186Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.39291454
187NF-kappa B signaling pathway_Homo sapiens_hsa040640.37273755
188Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.37227494
189Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.36116114
190Homologous recombination_Homo sapiens_hsa034400.34421628
191Fatty acid degradation_Homo sapiens_hsa000710.33449995
192Mineral absorption_Homo sapiens_hsa049780.32993414

Most similar genes based on co-expression Upload to Enrichr

Tissue Expression Export image »

Cell Line Expression Export image »