

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | female gonad development (GO:0008585) | 8.44842988 |
| 2 | regulation of telomere maintenance via telomerase (GO:0032210) | 8.03060149 |
| 3 | stress granule assembly (GO:0034063) | 7.18110262 |
| 4 | inner mitochondrial membrane organization (GO:0007007) | 6.79231333 |
| 5 | central nervous system neuron axonogenesis (GO:0021955) | 6.75834005 |
| 6 | male meiosis (GO:0007140) | 6.56734852 |
| 7 | cranial suture morphogenesis (GO:0060363) | 6.49441857 |
| 8 | negative regulation of telomere maintenance (GO:0032205) | 6.44702629 |
| 9 | peptidyl-lysine dimethylation (GO:0018027) | 6.23996726 |
| 10 | regulation of G0 to G1 transition (GO:0070316) | 6.21701792 |
| 11 | thyroid hormone generation (GO:0006590) | 6.14071358 |
| 12 | cellular response to hepatocyte growth factor stimulus (GO:0035729) | 5.87816573 |
| 13 | response to hepatocyte growth factor (GO:0035728) | 5.87816573 |
| 14 | negative regulation of glycoprotein biosynthetic process (GO:0010561) | 5.80759150 |
| 15 | centrosome duplication (GO:0051298) | 5.80282281 |
| 16 | negative regulation of epidermal growth factor-activated receptor activity (GO:0007175) | 5.69773613 |
| 17 | lipid translocation (GO:0034204) | 5.62629355 |
| 18 | phospholipid translocation (GO:0045332) | 5.62629355 |
| 19 | ventricular trabecula myocardium morphogenesis (GO:0003222) | 5.49658732 |
| 20 | regulation of protein glycosylation (GO:0060049) | 5.42719066 |
| 21 | apoptotic DNA fragmentation (GO:0006309) | 5.31035124 |
| 22 | positive regulation of keratinocyte differentiation (GO:0045618) | 5.26290659 |
| 23 | viral protein processing (GO:0019082) | 5.09710791 |
| 24 | DNA strand renaturation (GO:0000733) | 5.02938568 |
| 25 | thyroid hormone metabolic process (GO:0042403) | 5.01360550 |
| 26 | intermediate filament cytoskeleton organization (GO:0045104) | 4.87999954 |
| 27 | negative regulation of translation involved in gene silencing by miRNA (GO:0035278) | 4.79319917 |
| 28 | negative regulation of translation, ncRNA-mediated (GO:0040033) | 4.79319917 |
| 29 | regulation of translation, ncRNA-mediated (GO:0045974) | 4.79319917 |
| 30 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.75355269 |
| 31 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.75355269 |
| 32 | intermediate filament-based process (GO:0045103) | 4.73916020 |
| 33 | regulation of natural killer cell mediated cytotoxicity (GO:0042269) | 4.66108144 |
| 34 | regulation of natural killer cell mediated immunity (GO:0002715) | 4.66108144 |
| 35 | heart trabecula morphogenesis (GO:0061384) | 4.42885479 |
| 36 | negative regulation of glycoprotein metabolic process (GO:1903019) | 4.41290852 |
| 37 | negative regulation of keratinocyte proliferation (GO:0010839) | 4.34777790 |
| 38 | maintenance of protein location in nucleus (GO:0051457) | 4.17712843 |
| 39 | positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145) | 4.13646131 |
| 40 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 4.12929847 |
| 41 | regulation of sister chromatid cohesion (GO:0007063) | 4.11200191 |
| 42 | craniofacial suture morphogenesis (GO:0097094) | 4.04222767 |
| 43 | mitotic G2 DNA damage checkpoint (GO:0007095) | 3.98390149 |
| 44 | trabecula morphogenesis (GO:0061383) | 3.87446366 |
| 45 | regulation of telomere maintenance (GO:0032204) | 3.85008471 |
| 46 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.81204564 |
| 47 | cellular response to thyroid hormone stimulus (GO:0097067) | 3.79891023 |
| 48 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 3.79610722 |
| 49 | hydrogen peroxide biosynthetic process (GO:0050665) | 3.77880588 |
| 50 | galactose metabolic process (GO:0006012) | 3.77151501 |
| 51 | negative regulation of protein tyrosine kinase activity (GO:0061099) | 3.66401512 |
| 52 | intracellular protein transmembrane import (GO:0044743) | 3.60000861 |
| 53 | negative regulation of receptor activity (GO:2000272) | 3.57466372 |
| 54 | regulation of histone phosphorylation (GO:0033127) | 3.55461731 |
| 55 | positive regulation of epidermal cell differentiation (GO:0045606) | 3.54044655 |
| 56 | embryonic heart tube development (GO:0035050) | 3.53115550 |
| 57 | vitamin transmembrane transport (GO:0035461) | 3.48375124 |
| 58 | middle ear morphogenesis (GO:0042474) | 3.46034417 |
| 59 | reactive oxygen species biosynthetic process (GO:1903409) | 3.43147377 |
| 60 | positive regulation of protein import into nucleus, translocation (GO:0033160) | 3.42162986 |
| 61 | parturition (GO:0007567) | 3.39689398 |
| 62 | protein-cofactor linkage (GO:0018065) | 3.36697839 |
| 63 | regulation of voltage-gated calcium channel activity (GO:1901385) | 3.36164184 |
| 64 | SCF-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0031146) | 3.34977950 |
| 65 | mast cell activation (GO:0045576) | 3.29234813 |
| 66 | positive regulation of transcription regulatory region DNA binding (GO:2000679) | 3.28207148 |
| 67 | regulation of membrane lipid distribution (GO:0097035) | 3.27445859 |
| 68 | natural killer cell activation (GO:0030101) | 3.23555015 |
| 69 | head development (GO:0060322) | 3.21861584 |
| 70 | androgen biosynthetic process (GO:0006702) | 3.21577184 |
| 71 | cell migration involved in heart development (GO:0060973) | 3.21470871 |
| 72 | outer ear morphogenesis (GO:0042473) | 3.21138026 |
| 73 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.10927382 |
| 74 | mitotic G2/M transition checkpoint (GO:0044818) | 3.10891485 |
| 75 | ATP synthesis coupled proton transport (GO:0015986) | 3.07537997 |
| 76 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 3.07537997 |
| 77 | peptidyl-lysine methylation (GO:0018022) | 3.04753271 |
| 78 | mRNA transcription from RNA polymerase II promoter (GO:0042789) | 2.97175868 |
| 79 | regulation of antigen processing and presentation of peptide antigen (GO:0002583) | 2.96694950 |
| 80 | regulation of interferon-beta biosynthetic process (GO:0045357) | 2.95136836 |
| 81 | ovulation cycle (GO:0042698) | 2.88030812 |
| 82 | RNA destabilization (GO:0050779) | 2.87391506 |
| 83 | regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043516) | 2.85157531 |
| 84 | endocardial cushion morphogenesis (GO:0003203) | 2.83636444 |
| 85 | virion assembly (GO:0019068) | 2.79418600 |
| 86 | regulation of keratinocyte proliferation (GO:0010837) | 2.77602807 |
| 87 | superoxide anion generation (GO:0042554) | 2.76090707 |
| 88 | negative regulation of cation channel activity (GO:2001258) | 2.75588086 |
| 89 | histone H3-K4 trimethylation (GO:0080182) | 2.75386813 |
| 90 | negative regulation of catenin import into nucleus (GO:0035414) | 2.74961379 |
| 91 | intracellular protein transmembrane transport (GO:0065002) | 2.73061279 |
| 92 | embryonic hindlimb morphogenesis (GO:0035116) | 2.72024373 |
| 93 | pyrimidine-containing compound transmembrane transport (GO:0072531) | 2.70006628 |
| 94 | vitamin transport (GO:0051180) | 2.67664174 |
| 95 | neurofilament cytoskeleton organization (GO:0060052) | 18.2071320 |
| 96 | regulation of DNA methylation (GO:0044030) | 14.0017510 |
| 97 | glyoxylate metabolic process (GO:0046487) | 11.1593810 |
| 98 | ectoderm development (GO:0007398) | 10.9664226 |
| 99 | chaperone-mediated protein transport (GO:0072321) | 10.9176387 |
| 100 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 10.5391544 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 5.71929022 |
| 2 | IGF1R_20145208_ChIP-Seq_DFB_Human | 4.37667460 |
| 3 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 4.21221314 |
| 4 | IRF1_19129219_ChIP-ChIP_H3396_Human | 4.08383617 |
| 5 | VDR_22108803_ChIP-Seq_LS180_Human | 3.74917645 |
| 6 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 3.24520598 |
| 7 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 3.16815749 |
| 8 | VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human | 2.72112392 |
| 9 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.67962449 |
| 10 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 2.55900463 |
| 11 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 2.45732474 |
| 12 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.31914800 |
| 13 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.22247548 |
| 14 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.99456838 |
| 15 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.93968604 |
| 16 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.92247870 |
| 17 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.83282398 |
| 18 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.83040980 |
| 19 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.80559453 |
| 20 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.75036772 |
| 21 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.70579244 |
| 22 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.66722745 |
| 23 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.60929218 |
| 24 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.60929218 |
| 25 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.59410592 |
| 26 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.57733639 |
| 27 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.55217432 |
| 28 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.53188063 |
| 29 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.52541694 |
| 30 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.50625686 |
| 31 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 1.50175202 |
| 32 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.49594541 |
| 33 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.49500246 |
| 34 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.46808517 |
| 35 | TP53_16413492_ChIP-PET_HCT116_Human | 1.45732980 |
| 36 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.41814092 |
| 37 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.40293718 |
| 38 | MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse | 1.40078771 |
| 39 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.39836317 |
| 40 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.38087893 |
| 41 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.32310370 |
| 42 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.32256347 |
| 43 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.31228661 |
| 44 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.27895482 |
| 45 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 1.26803639 |
| 46 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.26264980 |
| 47 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.24951644 |
| 48 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.24862856 |
| 49 | VDR_21846776_ChIP-Seq_THP-1_Human | 1.24312206 |
| 50 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23681165 |
| 51 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.19654361 |
| 52 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.19292530 |
| 53 | PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse | 1.17754825 |
| 54 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.17567917 |
| 55 | CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.17512689 |
| 56 | MYC_22102868_ChIP-Seq_BL_Human | 1.16757199 |
| 57 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15860330 |
| 58 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.14654196 |
| 59 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.14380313 |
| 60 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.13202677 |
| 61 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.10160120 |
| 62 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.09406727 |
| 63 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.04907564 |
| 64 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.04395300 |
| 65 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.03912509 |
| 66 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.03806079 |
| 67 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.03477165 |
| 68 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.02165527 |
| 69 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.99142590 |
| 70 | KLF4_19829295_ChIP-Seq_ESCs_Human | 0.98512515 |
| 71 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 0.97607364 |
| 72 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.96810491 |
| 73 | RNF2_27304074_Chip-Seq_NSC_Mouse | 0.96414321 |
| 74 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.96334638 |
| 75 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.95737247 |
| 76 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 0.95096493 |
| 77 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 0.94473478 |
| 78 | MYC_27129775_Chip-Seq_CORNEA_Mouse | 0.93468886 |
| 79 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.93362227 |
| 80 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 0.93198133 |
| 81 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 0.93198133 |
| 82 | GATA2_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.92496460 |
| 83 | NANOG_20526341_ChIP-Seq_ESCs_Human | 0.92170133 |
| 84 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.88646341 |
| 85 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.88223217 |
| 86 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.87675261 |
| 87 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 0.87670713 |
| 88 | MYCN_27167114_Chip-Seq_NEUROBLASTOMA_Human | 0.87340173 |
| 89 | KDM2B_26808549_Chip-Seq_K562_Human | 0.86488926 |
| 90 | SMAD4_21741376_ChIP-Seq_HESCs_Human | 0.85712660 |
| 91 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.84599832 |
| 92 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.83349746 |
| 93 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 0.82577338 |
| 94 | KDM2B_26808549_Chip-Seq_REH_Human | 0.79431025 |
| 95 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.79397273 |
| 96 | CBP_21632823_ChIP-Seq_H3396_Human | 0.77884908 |
| 97 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.77545168 |
| 98 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 0.75679817 |
| 99 | NCOR_22424771_ChIP-Seq_293T_Human | 0.74381453 |
| 100 | AR_25329375_ChIP-Seq_VCAP_Human | 0.74316530 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003786_premature_aging | 4.72525975 |
| 2 | MP0002653_abnormal_ependyma_morphology | 4.37838051 |
| 3 | MP0002876_abnormal_thyroid_physiology | 4.36982110 |
| 4 | MP0004264_abnormal_extraembryonic_tissu | 3.32206593 |
| 5 | MP0003763_abnormal_thymus_physiology | 2.74722242 |
| 6 | MP0004885_abnormal_endolymph | 2.72964705 |
| 7 | MP0001986_abnormal_taste_sensitivity | 2.71026603 |
| 8 | MP0006082_CNS_inflammation | 2.45655657 |
| 9 | MP0005671_abnormal_response_to | 2.28658015 |
| 10 | MP0006276_abnormal_autonomic_nervous | 2.25967435 |
| 11 | MP0008995_early_reproductive_senescence | 11.9751677 |
| 12 | MP0008875_abnormal_xenobiotic_pharmacok | 1.98028850 |
| 13 | MP0004742_abnormal_vestibular_system | 1.93990328 |
| 14 | MP0000566_synostosis | 1.78126188 |
| 15 | MP0002132_abnormal_respiratory_system | 1.74905423 |
| 16 | MP0001849_ear_inflammation | 1.67673606 |
| 17 | MP0004270_analgesia | 1.67356448 |
| 18 | MP0010094_abnormal_chromosome_stability | 1.66190314 |
| 19 | MP0002697_abnormal_eye_size | 1.58458878 |
| 20 | MP0009333_abnormal_splenocyte_physiolog | 1.37481621 |
| 21 | MP0002127_abnormal_cardiovascular_syste | 1.37301529 |
| 22 | MP0001542_abnormal_bone_strength | 1.33240968 |
| 23 | MP0001119_abnormal_female_reproductive | 1.31543351 |
| 24 | MP0009046_muscle_twitch | 1.28995972 |
| 25 | MP0003879_abnormal_hair_cell | 1.24011051 |
| 26 | MP0005423_abnormal_somatic_nervous | 1.20510578 |
| 27 | MP0001440_abnormal_grooming_behavior | 1.15196864 |
| 28 | MP0003880_abnormal_central_pattern | 1.14052945 |
| 29 | MP0001485_abnormal_pinna_reflex | 1.11766031 |
| 30 | MP0009379_abnormal_foot_pigmentation | 1.08261652 |
| 31 | MP0003699_abnormal_female_reproductive | 1.07861312 |
| 32 | MP0003111_abnormal_nucleus_morphology | 1.06198879 |
| 33 | MP0000778_abnormal_nervous_system | 1.03416476 |
| 34 | MP0003936_abnormal_reproductive_system | 0.99837189 |
| 35 | MP0002735_abnormal_chemical_nociception | 0.99174882 |
| 36 | MP0004019_abnormal_vitamin_homeostasis | 0.98897944 |
| 37 | MP0001666_abnormal_nutrient_absorption | 0.98127557 |
| 38 | MP0005084_abnormal_gallbladder_morpholo | 0.93239252 |
| 39 | MP0006072_abnormal_retinal_apoptosis | 0.93105056 |
| 40 | MP0001881_abnormal_mammary_gland | 0.89280981 |
| 41 | MP0000955_abnormal_spinal_cord | 0.85791444 |
| 42 | MP0001790_abnormal_immune_system | 0.84806253 |
| 43 | MP0005387_immune_system_phenotype | 0.84806253 |
| 44 | MP0002734_abnormal_mechanical_nocicepti | 0.83985168 |
| 45 | MP0001905_abnormal_dopamine_level | 0.82680702 |
| 46 | MP0009745_abnormal_behavioral_response | 0.82478630 |
| 47 | MP0004859_abnormal_synaptic_plasticity | 0.82279812 |
| 48 | MP0002398_abnormal_bone_marrow | 0.81942283 |
| 49 | MP0005085_abnormal_gallbladder_physiolo | 0.79612735 |
| 50 | MP0002210_abnormal_sex_determination | 0.78833768 |
| 51 | MP0005025_abnormal_response_to | 0.78672208 |
| 52 | MP0002723_abnormal_immune_serum | 0.77835056 |
| 53 | MP0002837_dystrophic_cardiac_calcinosis | 0.76108105 |
| 54 | MP0002420_abnormal_adaptive_immunity | 0.74234000 |
| 55 | MP0003787_abnormal_imprinting | 0.73352831 |
| 56 | MP0008877_abnormal_DNA_methylation | 0.72433382 |
| 57 | MP0002067_abnormal_sensory_capabilities | 0.72411381 |
| 58 | MP0005508_abnormal_skeleton_morphology | 0.72247697 |
| 59 | MP0002184_abnormal_innervation | 0.71422877 |
| 60 | MP0001944_abnormal_pancreas_morphology | 0.71081661 |
| 61 | MP0000716_abnormal_immune_system | 0.71038258 |
| 62 | MP0004142_abnormal_muscle_tone | 0.70426301 |
| 63 | MP0000049_abnormal_middle_ear | 0.68703697 |
| 64 | MP0001819_abnormal_immune_cell | 0.68612346 |
| 65 | MP0004130_abnormal_muscle_cell | 0.66708154 |
| 66 | MP0000569_abnormal_digit_pigmentation | 0.65199364 |
| 67 | MP0000026_abnormal_inner_ear | 0.63718227 |
| 68 | MP0002234_abnormal_pharynx_morphology | 0.63010922 |
| 69 | MP0002429_abnormal_blood_cell | 0.62720788 |
| 70 | MP0002116_abnormal_craniofacial_bone | 0.61101596 |
| 71 | MP0001286_abnormal_eye_development | 0.61030600 |
| 72 | MP0002557_abnormal_social/conspecific_i | 0.60193372 |
| 73 | MP0003123_paternal_imprinting | 0.59491244 |
| 74 | MP0000920_abnormal_myelination | 0.59443868 |
| 75 | MP0003635_abnormal_synaptic_transmissio | 0.58547546 |
| 76 | MP0000343_altered_response_to | 0.57791459 |
| 77 | MP0008775_abnormal_heart_ventricle | 0.57636971 |
| 78 | MP0003866_abnormal_defecation | 0.55955428 |
| 79 | MP0009785_altered_susceptibility_to | 0.55667229 |
| 80 | MP0002752_abnormal_somatic_nervous | 0.55290343 |
| 81 | MP0002064_seizures | 0.54973660 |
| 82 | MP0003011_delayed_dark_adaptation | 0.53520268 |
| 83 | MP0002736_abnormal_nociception_after | 0.52476359 |
| 84 | MP0004145_abnormal_muscle_electrophysio | 0.52391813 |
| 85 | MP0002161_abnormal_fertility/fecundity | 0.52165368 |
| 86 | MP0001800_abnormal_humoral_immune | 0.51791971 |
| 87 | MP0001963_abnormal_hearing_physiology | 0.51245326 |
| 88 | MP0005000_abnormal_immune_tolerance | 0.51144070 |
| 89 | MP0002163_abnormal_gland_morphology | 0.50473815 |
| 90 | MP0001661_extended_life_span | 0.50003334 |
| 91 | MP0002272_abnormal_nervous_system | 0.49345203 |
| 92 | MP0003632_abnormal_nervous_system | 0.48703947 |
| 93 | MP0002882_abnormal_neuron_morphology | 0.48103082 |
| 94 | MP0000627_abnormal_mammary_gland | 0.46898708 |
| 95 | MP0003698_abnormal_male_reproductive | 0.45817506 |
| 96 | MP0001145_abnormal_male_reproductive | 0.45143050 |
| 97 | MP0003195_calcinosis | 0.44306823 |
| 98 | MP0003646_muscle_fatigue | 0.44151614 |
| 99 | MP0006292_abnormal_olfactory_placode | 0.42471931 |
| 100 | MP0005464_abnormal_platelet_physiology | 0.40541420 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Chromosomal breakage induced by crosslinking agents (HP:0003221) | 9.80150041 |
| 2 | Reticulocytopenia (HP:0001896) | 9.22705687 |
| 3 | Abnormality of the renal collecting system (HP:0004742) | 9.16064324 |
| 4 | Chromsome breakage (HP:0040012) | 8.61796234 |
| 5 | Abnormality of pyrimidine metabolism (HP:0004353) | 8.13481715 |
| 6 | Abnormality of DNA repair (HP:0003254) | 6.93447638 |
| 7 | Oral leukoplakia (HP:0002745) | 6.54796060 |
| 8 | Ureteral duplication (HP:0000073) | 6.33995044 |
| 9 | Aplastic anemia (HP:0001915) | 6.11843496 |
| 10 | Duplication of thumb phalanx (HP:0009942) | 5.80279336 |
| 11 | Ectopic kidney (HP:0000086) | 5.25771416 |
| 12 | Increased serum pyruvate (HP:0003542) | 4.88263652 |
| 13 | Absent thumb (HP:0009777) | 4.61383423 |
| 14 | Autoimmune thrombocytopenia (HP:0001973) | 4.19515357 |
| 15 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 4.09483640 |
| 16 | Abnormality of glycolysis (HP:0004366) | 4.08425463 |
| 17 | Enlarged epiphyses (HP:0010580) | 4.01998163 |
| 18 | Thyroid-stimulating hormone excess (HP:0002925) | 3.88032621 |
| 19 | Meckel diverticulum (HP:0002245) | 3.60371981 |
| 20 | Absent radius (HP:0003974) | 3.56510629 |
| 21 | Eosinophilia (HP:0001880) | 3.54183729 |
| 22 | Abnormality of the preputium (HP:0100587) | 3.49803092 |
| 23 | Abnormality of the ileum (HP:0001549) | 3.45128931 |
| 24 | Absent forearm bone (HP:0003953) | 3.40109351 |
| 25 | Aplasia involving forearm bones (HP:0009822) | 3.40109351 |
| 26 | Horseshoe kidney (HP:0000085) | 3.39849222 |
| 27 | Pancytopenia (HP:0001876) | 3.36310350 |
| 28 | Abnormality of B cell number (HP:0010975) | 3.32616402 |
| 29 | Abnormality of T cell number (HP:0011839) | 3.23982224 |
| 30 | Autoimmune hemolytic anemia (HP:0001890) | 3.18892606 |
| 31 | Stomach cancer (HP:0012126) | 3.08446373 |
| 32 | Hypergonadotropic hypogonadism (HP:0000815) | 3.01733983 |
| 33 | Renal cortical cysts (HP:0000803) | 3.01231686 |
| 34 | Flattened epiphyses (HP:0003071) | 3.00106294 |
| 35 | Clubbing of toes (HP:0100760) | 2.91510649 |
| 36 | Rough bone trabeculation (HP:0100670) | 2.90794865 |
| 37 | Increased IgM level (HP:0003496) | 2.82681658 |
| 38 | Abnormality of chromosome stability (HP:0003220) | 2.77486351 |
| 39 | Granulocytopenia (HP:0001913) | 2.75402294 |
| 40 | Hypoplasia of the capital femoral epiphysis (HP:0003090) | 2.70180444 |
| 41 | Abnormality of eosinophils (HP:0001879) | 2.68482477 |
| 42 | Abnormality of the carotid arteries (HP:0005344) | 2.66522627 |
| 43 | Abnormality of reticulocytes (HP:0004312) | 2.59861163 |
| 44 | Abnormality of the vertebral endplates (HP:0005106) | 2.57827832 |
| 45 | Abnormality of nucleobase metabolism (HP:0010932) | 2.51967492 |
| 46 | Joint swelling (HP:0001386) | 2.50569806 |
| 47 | Increased hepatocellular lipid droplets (HP:0006565) | 2.41928189 |
| 48 | Short thumb (HP:0009778) | 2.40629817 |
| 49 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.40443193 |
| 50 | Leukopenia (HP:0001882) | 2.31939335 |
| 51 | Abnormality of T cells (HP:0002843) | 2.27868973 |
| 52 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.27751972 |
| 53 | Partial duplication of the phalanx of hand (HP:0009999) | 2.27437182 |
| 54 | Cellular immunodeficiency (HP:0005374) | 2.27288590 |
| 55 | Bone marrow hypocellularity (HP:0005528) | 2.27033103 |
| 56 | Abnormality of the epiphysis of the femoral head (HP:0010574) | 2.26176133 |
| 57 | Aplasia/Hypoplasia of the capital femoral epiphysis (HP:0005003) | 2.24486857 |
| 58 | Absent epiphyses (HP:0010577) | 2.24486857 |
| 59 | Neutropenia (HP:0001875) | 2.23444108 |
| 60 | Duodenal stenosis (HP:0100867) | 2.18283021 |
| 61 | Small intestinal stenosis (HP:0012848) | 2.18283021 |
| 62 | Renal Fanconi syndrome (HP:0001994) | 2.16428224 |
| 63 | Abnormal trabecular bone morphology (HP:0100671) | 2.15702653 |
| 64 | Coronal craniosynostosis (HP:0004440) | 2.13433829 |
| 65 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 2.07903578 |
| 66 | Abnormality of femoral epiphyses (HP:0006499) | 2.07903578 |
| 67 | Megalocornea (HP:0000485) | 2.06955481 |
| 68 | Spinal cord lesions (HP:0100561) | 2.05875114 |
| 69 | Syringomyelia (HP:0003396) | 2.05875114 |
| 70 | Abnormality of the femoral head (HP:0003368) | 2.04533201 |
| 71 | Renal agenesis (HP:0000104) | 2.03821540 |
| 72 | Lipid accumulation in hepatocytes (HP:0006561) | 2.01425955 |
| 73 | Duplicated collecting system (HP:0000081) | 10.2203033 |
| 74 | Hypochromic anemia (HP:0001931) | 1.98185452 |
| 75 | Turricephaly (HP:0000262) | 1.95767470 |
| 76 | Pallor (HP:0000980) | 1.87403176 |
| 77 | Tracheoesophageal fistula (HP:0002575) | 1.87109438 |
| 78 | Abnormality of the duodenum (HP:0002246) | 1.81736607 |
| 79 | Triphalangeal thumb (HP:0001199) | 1.80363194 |
| 80 | Disproportionate short-trunk short stature (HP:0003521) | 1.76578059 |
| 81 | Trigonocephaly (HP:0000243) | 1.74295381 |
| 82 | T lymphocytopenia (HP:0005403) | 1.74133340 |
| 83 | Leukocytosis (HP:0001974) | 1.65643757 |
| 84 | Waddling gait (HP:0002515) | 1.65213744 |
| 85 | Mutism (HP:0002300) | 1.64691970 |
| 86 | Premature graying of hair (HP:0002216) | 1.63395739 |
| 87 | Truncal obesity (HP:0001956) | 1.59487916 |
| 88 | Abnormality of cells of the lymphoid lineage (HP:0012140) | 1.57829469 |
| 89 | Abnormality of the 2nd finger (HP:0004100) | 1.57614678 |
| 90 | Thoracic kyphosis (HP:0002942) | 1.55690982 |
| 91 | Exertional dyspnea (HP:0002875) | 1.55324672 |
| 92 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.54956530 |
| 93 | Abnormality of the parietal bone (HP:0002696) | 1.53530680 |
| 94 | Anomalous pulmonary venous return (HP:0010772) | 1.53026893 |
| 95 | Fetal akinesia sequence (HP:0001989) | 1.52469319 |
| 96 | Progressive neurologic deterioration (HP:0002344) | 1.51826783 |
| 97 | Abnormality of the renal cortex (HP:0011035) | 1.47201552 |
| 98 | Abnormality of cochlea (HP:0000375) | 1.45909558 |
| 99 | Fine hair (HP:0002213) | 1.44377131 |
| 100 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 1.44003338 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MAP4K1 | 7.28801909 |
| 2 | TXK | 7.26847544 |
| 3 | BCKDK | 3.58591331 |
| 4 | TAOK3 | 12.4762092 |
| 5 | ZAP70 | 1.76723637 |
| 6 | TESK2 | 1.61406708 |
| 7 | PRPF4B | 1.49737078 |
| 8 | CAMK1D | 1.37705901 |
| 9 | IKBKE | 0.89497513 |
| 10 | CAMK1G | 0.89074177 |
| 11 | SGK1 | 0.82594008 |
| 12 | MUSK | 0.80921893 |
| 13 | EPHB2 | 0.80570641 |
| 14 | TESK1 | 0.79085413 |
| 15 | BMPR1B | 0.68208253 |
| 16 | TYRO3 | 0.67689315 |
| 17 | PIK3CA | 0.67568550 |
| 18 | LIMK1 | 0.64700374 |
| 19 | TBK1 | 0.59941146 |
| 20 | NLK | 0.57957747 |
| 21 | MAPK13 | 0.55115566 |
| 22 | DYRK1B | 0.54580915 |
| 23 | SYK | 0.54164877 |
| 24 | ITK | 0.49632768 |
| 25 | WNK3 | 0.48413546 |
| 26 | SGK2 | 0.47443831 |
| 27 | LCK | 0.46294958 |
| 28 | ATR | 0.44123059 |
| 29 | JAK1 | 0.43099370 |
| 30 | SGK494 | 0.37999236 |
| 31 | SGK223 | 0.37999236 |
| 32 | LYN | 0.35999569 |
| 33 | HCK | 0.34739711 |
| 34 | NTRK2 | 0.32300705 |
| 35 | MAPK12 | 0.29453408 |
| 36 | DYRK1A | 0.29126988 |
| 37 | PRKAA1 | 0.29029775 |
| 38 | NTRK1 | 0.27809679 |
| 39 | MAP4K2 | 0.26618849 |
| 40 | ADRBK2 | 0.26516280 |
| 41 | MINK1 | 0.24577047 |
| 42 | INSRR | 0.24033629 |
| 43 | OBSCN | 0.23783759 |
| 44 | PRKAA2 | 0.23573035 |
| 45 | IGF1R | 0.23432355 |
| 46 | CAMK1 | 0.23041025 |
| 47 | CSNK1G1 | 0.22798481 |
| 48 | GRK1 | 0.22719302 |
| 49 | FYN | 0.22442114 |
| 50 | PINK1 | 0.22330465 |
| 51 | CSNK1A1 | 0.22258946 |
| 52 | PRKCQ | 0.21714822 |
| 53 | GSK3A | 0.20941944 |
| 54 | OXSR1 | 0.19980227 |
| 55 | PRKCG | 0.19850310 |
| 56 | AKT1 | 0.19572830 |
| 57 | IKBKB | 0.17718998 |
| 58 | ERBB2 | 0.16954322 |
| 59 | MARK1 | 0.16822184 |
| 60 | MAP3K4 | 0.16207847 |
| 61 | MAP2K7 | 0.16132309 |
| 62 | SGK3 | 0.16109390 |
| 63 | DAPK3 | 0.15639837 |
| 64 | WNK4 | 0.14575740 |
| 65 | INSR | 0.14244808 |
| 66 | MAPK3 | 0.13578919 |
| 67 | RPS6KA1 | 0.13112388 |
| 68 | AKT2 | 0.12524221 |
| 69 | TIE1 | 0.12270865 |
| 70 | DYRK2 | 0.11963725 |
| 71 | MTOR | 0.10796530 |
| 72 | GRK7 | 0.10310466 |
| 73 | CASK | 0.10261071 |
| 74 | CDK14 | 0.09656426 |
| 75 | PIM1 | 0.09128786 |
| 76 | MAPK15 | 0.08858637 |
| 77 | PRKACA | 0.08514615 |
| 78 | BTK | 0.08110303 |
| 79 | FRK | 0.08053771 |
| 80 | MAPK8 | 0.07899512 |
| 81 | PRKCA | 0.07689068 |
| 82 | CSNK1E | 0.07496321 |
| 83 | MAPK14 | 0.07195317 |
| 84 | ADRBK1 | 0.06371630 |
| 85 | MAPKAPK2 | 0.06144694 |
| 86 | ATM | 0.05808941 |
| 87 | PRKCE | 0.05742872 |
| 88 | RPS6KA3 | 0.04442785 |
| 89 | PAK3 | 0.04321854 |
| 90 | TNK2 | 0.03853141 |
| 91 | PRKCB | 0.03784186 |
| 92 | CDK15 | 0.03782520 |
| 93 | PTK6 | 0.03513200 |
| 94 | ERBB3 | 0.03305513 |
| 95 | PIM2 | 0.03127326 |
| 96 | MAP3K5 | 0.03055083 |
| 97 | CAMK2A | 0.02851995 |
| 98 | CDK5 | 0.02761524 |
| 99 | ICK | 0.02337476 |
| 100 | AKT3 | 0.02291572 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 6.13229520 |
| 2 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 3.16608884 |
| 3 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.00275636 |
| 4 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 2.54460076 |
| 5 | Pyruvate metabolism_Homo sapiens_hsa00620 | 2.50650380 |
| 6 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.42021575 |
| 7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.31407141 |
| 8 | Graft-versus-host disease_Homo sapiens_hsa05332 | 2.27394347 |
| 9 | Allograft rejection_Homo sapiens_hsa05330 | 2.27169727 |
| 10 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 2.25746105 |
| 11 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 2.16314250 |
| 12 | Galactose metabolism_Homo sapiens_hsa00052 | 2.01117457 |
| 13 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 1.88259998 |
| 14 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.79337971 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.74453761 |
| 16 | Ribosome_Homo sapiens_hsa03010 | 1.71229999 |
| 17 | Parkinsons disease_Homo sapiens_hsa05012 | 1.71096440 |
| 18 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.69823795 |
| 19 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.64510374 |
| 20 | Asthma_Homo sapiens_hsa05310 | 1.58108423 |
| 21 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.50289819 |
| 22 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.50033532 |
| 23 | Basal transcription factors_Homo sapiens_hsa03022 | 1.37328866 |
| 24 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.34051749 |
| 25 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.30005143 |
| 26 | Mismatch repair_Homo sapiens_hsa03430 | 1.29832077 |
| 27 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.26317993 |
| 28 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 1.24621475 |
| 29 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.22412415 |
| 30 | Malaria_Homo sapiens_hsa05144 | 1.18144226 |
| 31 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 1.17178505 |
| 32 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.16890401 |
| 33 | Pancreatic secretion_Homo sapiens_hsa04972 | 1.16555074 |
| 34 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.12653814 |
| 35 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.11127500 |
| 36 | Viral myocarditis_Homo sapiens_hsa05416 | 1.08266129 |
| 37 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.08019623 |
| 38 | Alzheimers disease_Homo sapiens_hsa05010 | 1.06955988 |
| 39 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.05694214 |
| 40 | Salivary secretion_Homo sapiens_hsa04970 | 1.05328412 |
| 41 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.98581312 |
| 42 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.97808461 |
| 43 | Morphine addiction_Homo sapiens_hsa05032 | 0.97116158 |
| 44 | Bile secretion_Homo sapiens_hsa04976 | 0.92179100 |
| 45 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.90970148 |
| 46 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.86596962 |
| 47 | Nicotine addiction_Homo sapiens_hsa05033 | 0.86482352 |
| 48 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.85170431 |
| 49 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.83644266 |
| 50 | Protein export_Homo sapiens_hsa03060 | 0.82915900 |
| 51 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.72660842 |
| 52 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.70752711 |
| 53 | Huntingtons disease_Homo sapiens_hsa05016 | 0.70556615 |
| 54 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.68414043 |
| 55 | Phototransduction_Homo sapiens_hsa04744 | 0.66116641 |
| 56 | Olfactory transduction_Homo sapiens_hsa04740 | 0.63798105 |
| 57 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.63473624 |
| 58 | Circadian entrainment_Homo sapiens_hsa04713 | 0.62192106 |
| 59 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.61989471 |
| 60 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.61495354 |
| 61 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.61068931 |
| 62 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.60823039 |
| 63 | Platelet activation_Homo sapiens_hsa04611 | 0.60804465 |
| 64 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.59024299 |
| 65 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.58413406 |
| 66 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.57405872 |
| 67 | Insulin secretion_Homo sapiens_hsa04911 | 0.57043511 |
| 68 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.56375717 |
| 69 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.56321808 |
| 70 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.55402321 |
| 71 | Endocytosis_Homo sapiens_hsa04144 | 0.55157418 |
| 72 | GABAergic synapse_Homo sapiens_hsa04727 | 0.53030054 |
| 73 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.50398227 |
| 74 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.50333577 |
| 75 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.49921078 |
| 76 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.49644635 |
| 77 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.48084143 |
| 78 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.47793821 |
| 79 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.47153967 |
| 80 | Pertussis_Homo sapiens_hsa05133 | 0.45095958 |
| 81 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.43604880 |
| 82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.42182135 |
| 83 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.42064563 |
| 84 | Phagosome_Homo sapiens_hsa04145 | 0.41544136 |
| 85 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.39750279 |
| 86 | Mineral absorption_Homo sapiens_hsa04978 | 0.37475954 |
| 87 | Retinol metabolism_Homo sapiens_hsa00830 | 0.36541408 |
| 88 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.35409079 |
| 89 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.32701568 |
| 90 | Taste transduction_Homo sapiens_hsa04742 | 0.31022030 |
| 91 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.30497889 |
| 92 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.29629511 |
| 93 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.27873628 |
| 94 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.26926210 |
| 95 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.24847310 |
| 96 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.24174858 |
| 97 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.23024251 |
| 98 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.22810431 |
| 99 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.22762042 |
| 100 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.22167390 |

