Rank | Gene Set | Z-score |
---|---|---|
1 | outer ear morphogenesis (GO:0042473) | 8.44748037 |
2 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 8.07312204 |
3 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 8.07312204 |
4 | artery development (GO:0060840) | 7.67314184 |
5 | polyamine biosynthetic process (GO:0006596) | 7.32486248 |
6 | facial nerve structural organization (GO:0021612) | 7.06312483 |
7 | adenylate cyclase-activating dopamine receptor signaling pathway (GO:0007191) | 6.86046086 |
8 | negative regulation of sodium ion transport (GO:0010766) | 6.17648220 |
9 | synaptic transmission, dopaminergic (GO:0001963) | 5.74410308 |
10 | prepulse inhibition (GO:0060134) | 5.73670645 |
11 | behavioral response to cocaine (GO:0048148) | 5.72606635 |
12 | regulation of neurotransmitter uptake (GO:0051580) | 5.59164443 |
13 | arachidonic acid secretion (GO:0050482) | 5.51528216 |
14 | icosanoid secretion (GO:0032309) | 5.51528216 |
15 | multicellular organismal movement (GO:0050879) | 5.49876252 |
16 | musculoskeletal movement (GO:0050881) | 5.49876252 |
17 | G-protein coupled receptor internalization (GO:0002031) | 5.46559660 |
18 | low-density lipoprotein particle clearance (GO:0034383) | 5.33442184 |
19 | amine catabolic process (GO:0009310) | 5.23127318 |
20 | cellular biogenic amine catabolic process (GO:0042402) | 5.23127318 |
21 | polyamine metabolic process (GO:0006595) | 5.17922329 |
22 | response to histamine (GO:0034776) | 5.09299745 |
23 | reflex (GO:0060004) | 5.08503227 |
24 | cranial nerve structural organization (GO:0021604) | 5.06164297 |
25 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 5.00812389 |
26 | cellular biogenic amine biosynthetic process (GO:0042401) | 5.00457051 |
27 | ubiquinone biosynthetic process (GO:0006744) | 4.78994172 |
28 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 4.74220842 |
29 | amine biosynthetic process (GO:0009309) | 4.72303233 |
30 | fatty acid derivative transport (GO:1901571) | 4.51322147 |
31 | icosanoid transport (GO:0071715) | 4.51322147 |
32 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 4.38377293 |
33 | mitochondrion morphogenesis (GO:0070584) | 4.33611912 |
34 | ubiquinone metabolic process (GO:0006743) | 4.31708193 |
35 | regulation of synaptic transmission, dopaminergic (GO:0032225) | 4.25658710 |
36 | fatty acid homeostasis (GO:0055089) | 4.21696758 |
37 | cochlea development (GO:0090102) | 4.01314004 |
38 | cardiovascular system development (GO:0072358) | 3.99115898 |
39 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.98252872 |
40 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.98252872 |
41 | glycerol metabolic process (GO:0006071) | 3.90224413 |
42 | quinone biosynthetic process (GO:1901663) | 3.87820422 |
43 | platelet dense granule organization (GO:0060155) | 3.85900323 |
44 | DNA deamination (GO:0045006) | 3.84914328 |
45 | negative regulation of glial cell differentiation (GO:0045686) | 3.76612540 |
46 | regulation of proton transport (GO:0010155) | 3.76231357 |
47 | substrate-independent telencephalic tangential migration (GO:0021826) | 3.75203010 |
48 | substrate-independent telencephalic tangential interneuron migration (GO:0021843) | 3.75203010 |
49 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 3.72385820 |
50 | positive regulation of renal sodium excretion (GO:0035815) | 3.71398389 |
51 | positive regulation of cellular amine metabolic process (GO:0033240) | 3.70347965 |
52 | cell morphogenesis involved in neuron differentiation (GO:0048667) | 3.58763394 |
53 | negative regulation of mast cell activation (GO:0033004) | 3.58345172 |
54 | regulation of circadian sleep/wake cycle (GO:0042749) | 3.47014744 |
55 | regulation of circadian sleep/wake cycle, sleep (GO:0045187) | 3.47014744 |
56 | negative regulation of nitric-oxide synthase activity (GO:0051001) | 3.40049568 |
57 | cellular response to interferon-beta (GO:0035458) | 3.39935314 |
58 | cytidine deamination (GO:0009972) | 3.39823618 |
59 | cytidine metabolic process (GO:0046087) | 3.39823618 |
60 | cytidine catabolic process (GO:0006216) | 3.39823618 |
61 | alditol metabolic process (GO:0019400) | 3.39185145 |
62 | regulation of dopamine secretion (GO:0014059) | 3.36532459 |
63 | response to amphetamine (GO:0001975) | 3.33608943 |
64 | peristalsis (GO:0030432) | 3.32154421 |
65 | nephron tubule morphogenesis (GO:0072078) | 3.31468096 |
66 | nephron epithelium morphogenesis (GO:0072088) | 3.31468096 |
67 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 3.22864476 |
68 | circadian sleep/wake cycle process (GO:0022410) | 3.20785560 |
69 | regulation of mitochondrial fission (GO:0090140) | 3.18229153 |
70 | anatomical structure arrangement (GO:0048532) | 3.16033308 |
71 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.15784004 |
72 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.15784004 |
73 | NADH dehydrogenase complex assembly (GO:0010257) | 3.15784004 |
74 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 3.15715552 |
75 | mitotic cell cycle arrest (GO:0071850) | 3.14722086 |
76 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.12723581 |
77 | negative regulation of telomere maintenance (GO:0032205) | 3.10002793 |
78 | regulation of cellular respiration (GO:0043457) | 3.08415036 |
79 | regulation of establishment of cell polarity (GO:2000114) | 3.01639049 |
80 | spliceosomal complex assembly (GO:0000245) | 2.99943419 |
81 | natural killer cell mediated immunity (GO:0002228) | 2.95985010 |
82 | natural killer cell mediated cytotoxicity (GO:0042267) | 2.95985010 |
83 | behavioral response to nicotine (GO:0035095) | 2.95722291 |
84 | respiratory chain complex IV assembly (GO:0008535) | 2.92795022 |
85 | plasma lipoprotein particle clearance (GO:0034381) | 2.89022773 |
86 | heparan sulfate proteoglycan metabolic process (GO:0030201) | 2.86665535 |
87 | L-methionine salvage (GO:0071267) | 2.86044310 |
88 | L-methionine biosynthetic process (GO:0071265) | 2.86044310 |
89 | amino acid salvage (GO:0043102) | 2.86044310 |
90 | diacylglycerol metabolic process (GO:0046339) | 2.84538687 |
91 | motor neuron axon guidance (GO:0008045) | 2.83287789 |
92 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 2.76539706 |
93 | somite development (GO:0061053) | 2.74625390 |
94 | regulation of interleukin-8 secretion (GO:2000482) | 2.74102126 |
95 | proteoglycan biosynthetic process (GO:0030166) | 2.72227848 |
96 | positive regulation of G-protein coupled receptor protein signaling pathway (GO:0045745) | 2.71906335 |
97 | protein complex biogenesis (GO:0070271) | 2.70466056 |
98 | mitochondrial RNA metabolic process (GO:0000959) | 2.68656297 |
99 | negative regulation of gliogenesis (GO:0014014) | 2.66813149 |
100 | potassium ion import (GO:0010107) | 2.66407477 |
Rank | Gene Set | Z-score |
---|---|---|
1 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 9.39369884 |
2 | ZNF274_21170338_ChIP-Seq_K562_Hela | 4.59002288 |
3 | VDR_22108803_ChIP-Seq_LS180_Human | 4.36109036 |
4 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 3.23939425 |
5 | EZH2_22144423_ChIP-Seq_EOC_Human | 3.08088277 |
6 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 2.79330777 |
7 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.37822876 |
8 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 2.34936839 |
9 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.30888760 |
10 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.26061813 |
11 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.20977004 |
12 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.18530932 |
13 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.96263842 |
14 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.84530153 |
15 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.80956364 |
16 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.79704626 |
17 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.65235545 |
18 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 1.64573167 |
19 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.60296263 |
20 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 1.56065410 |
21 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.54032879 |
22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.53074051 |
23 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.50741509 |
24 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.49718489 |
25 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.47766013 |
26 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.45182867 |
27 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.45086873 |
28 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.45086873 |
29 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.43235573 |
30 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 1.40986758 |
31 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.40431823 |
32 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.37034189 |
33 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.36292565 |
34 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.36292565 |
35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.35389058 |
36 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.33863424 |
37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.28247171 |
38 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.25774939 |
39 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.22628771 |
40 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.22267885 |
41 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.21550990 |
42 | ELK1_19687146_ChIP-ChIP_HELA_Human | 1.20991489 |
43 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.20252084 |
44 | NCOR_22424771_ChIP-Seq_293T_Human | 1.20145554 |
45 | EWS_26573619_Chip-Seq_HEK293_Human | 1.19706455 |
46 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.17945200 |
47 | GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.16930317 |
48 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.15892840 |
49 | VDR_23849224_ChIP-Seq_CD4+_Human | 1.15841300 |
50 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.15767594 |
51 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.14483108 |
52 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.14280839 |
53 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.13771708 |
54 | RCOR2_21632747_ChIP-Seq_MESCs_Mouse | 1.12736569 |
55 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.11733515 |
56 | KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse | 1.10978701 |
57 | JUN_21703547_ChIP-Seq_K562_Human | 1.10612924 |
58 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.09948313 |
59 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 1.08212199 |
60 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 1.08212199 |
61 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 1.08212199 |
62 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.07375170 |
63 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.06926822 |
64 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.06754554 |
65 | TCF4_23295773_ChIP-Seq_U87_Human | 1.06400667 |
66 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.05499484 |
67 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.04935567 |
68 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.03746367 |
69 | EBNA1_20929547_Chip-Seq_RAJI-cells_Human | 1.02980171 |
70 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.00846179 |
71 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.99669233 |
72 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.97472577 |
73 | ERA_21632823_ChIP-Seq_H3396_Human | 0.97124452 |
74 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.96756250 |
75 | AR_21572438_ChIP-Seq_LNCaP_Human | 0.96617644 |
76 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.95377833 |
77 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.94908702 |
78 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.94430273 |
79 | AR_25329375_ChIP-Seq_VCAP_Human | 0.93173672 |
80 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.92921141 |
81 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.91189524 |
82 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.90654651 |
83 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.90545447 |
84 | SOX9_26525672_Chip-Seq_Limbbuds_Mouse | 0.90358825 |
85 | ELK4_26923725_Chip-Seq_MESODERM_Mouse | 0.89875180 |
86 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.89441799 |
87 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 0.88764691 |
88 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.88268021 |
89 | FOXP3_21729870_ChIP-Seq_TREG_Human | 0.87926690 |
90 | GABP_19822575_ChIP-Seq_HepG2_Human | 0.87601168 |
91 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.86758273 |
92 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 0.86649279 |
93 | STAT3_23295773_ChIP-Seq_U87_Human | 0.84764222 |
94 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 0.84581416 |
95 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.83860634 |
96 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 0.83666415 |
97 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 0.83448221 |
98 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 0.83448221 |
99 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 0.82019757 |
100 | AR_20517297_ChIP-Seq_VCAP_Human | 0.81773350 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0000678_abnormal_parathyroid_gland | 4.19727324 |
2 | MP0009046_muscle_twitch | 3.78224434 |
3 | MP0008877_abnormal_DNA_methylation | 3.19299022 |
4 | MP0008872_abnormal_physiological_respon | 3.06678138 |
5 | MP0002735_abnormal_chemical_nociception | 2.38034406 |
6 | MP0004147_increased_porphyrin_level | 2.20685303 |
7 | MP0003646_muscle_fatigue | 2.19830993 |
8 | MP0001440_abnormal_grooming_behavior | 2.18236329 |
9 | MP0008875_abnormal_xenobiotic_pharmacok | 2.06397191 |
10 | MP0000049_abnormal_middle_ear | 2.01480628 |
11 | MP0005451_abnormal_body_composition | 10.4134973 |
12 | MP0003938_abnormal_ear_development | 1.96684667 |
13 | MP0001905_abnormal_dopamine_level | 1.96619358 |
14 | MP0000569_abnormal_digit_pigmentation | 1.93779454 |
15 | MP0001486_abnormal_startle_reflex | 1.91890582 |
16 | MP0002102_abnormal_ear_morphology | 1.84277062 |
17 | MP0008007_abnormal_cellular_replicative | 1.82003078 |
18 | MP0006072_abnormal_retinal_apoptosis | 1.75368882 |
19 | MP0003195_calcinosis | 1.74942514 |
20 | MP0004142_abnormal_muscle_tone | 1.63977443 |
21 | MP0004145_abnormal_muscle_electrophysio | 1.61765881 |
22 | MP0002837_dystrophic_cardiac_calcinosis | 1.54413211 |
23 | MP0003119_abnormal_digestive_system | 1.50109599 |
24 | MP0002638_abnormal_pupillary_reflex | 1.44212402 |
25 | MP0002067_abnormal_sensory_capabilities | 1.41393064 |
26 | MP0004885_abnormal_endolymph | 1.41201298 |
27 | MP0006292_abnormal_olfactory_placode | 1.36116889 |
28 | MP0002876_abnormal_thyroid_physiology | 1.34695497 |
29 | MP0003806_abnormal_nucleotide_metabolis | 1.30089359 |
30 | MP0009745_abnormal_behavioral_response | 1.28079899 |
31 | MP0003718_maternal_effect | 1.26997596 |
32 | MP0008058_abnormal_DNA_repair | 1.26987694 |
33 | MP0002733_abnormal_thermal_nociception | 1.26344361 |
34 | MP0004130_abnormal_muscle_cell | 1.26075638 |
35 | MP0003787_abnormal_imprinting | 1.25949457 |
36 | MP0005551_abnormal_eye_electrophysiolog | 1.20245801 |
37 | MP0000230_abnormal_systemic_arterial | 1.18136079 |
38 | MP0003315_abnormal_perineum_morphology | 1.17948639 |
39 | MP0001986_abnormal_taste_sensitivity | 1.14319427 |
40 | MP0003890_abnormal_embryonic-extraembry | 1.13118639 |
41 | MP0002177_abnormal_outer_ear | 1.11892884 |
42 | MP0004742_abnormal_vestibular_system | 1.06355587 |
43 | MP0001970_abnormal_pain_threshold | 1.06276915 |
44 | MP0001968_abnormal_touch/_nociception | 1.01737567 |
45 | MP0002111_abnormal_tail_morphology | 1.01689359 |
46 | MP0002572_abnormal_emotion/affect_behav | 0.97785358 |
47 | MP0005671_abnormal_response_to | 0.95470073 |
48 | MP0002063_abnormal_learning/memory/cond | 0.94239098 |
49 | MP0003283_abnormal_digestive_organ | 0.93331341 |
50 | MP0002736_abnormal_nociception_after | 0.92969776 |
51 | MP0003011_delayed_dark_adaptation | 0.91734194 |
52 | MP0001485_abnormal_pinna_reflex | 0.86687201 |
53 | MP0000026_abnormal_inner_ear | 0.86349237 |
54 | MP0001502_abnormal_circadian_rhythm | 0.85889048 |
55 | MP0006276_abnormal_autonomic_nervous | 0.85679037 |
56 | MP0008932_abnormal_embryonic_tissue | 0.84896596 |
57 | MP0005253_abnormal_eye_physiology | 0.84889442 |
58 | MP0002938_white_spotting | 0.84536066 |
59 | MP0002069_abnormal_eating/drinking_beha | 0.84458811 |
60 | MP0003136_yellow_coat_color | 0.83462638 |
61 | MP0004133_heterotaxia | 0.81646115 |
62 | MP0002108_abnormal_muscle_morphology | 0.81227715 |
63 | MP0002095_abnormal_skin_pigmentation | 0.81152601 |
64 | MP0002272_abnormal_nervous_system | 0.80210240 |
65 | MP0008995_early_reproductive_senescence | 0.79343477 |
66 | MP0005174_abnormal_tail_pigmentation | 0.78745585 |
67 | MP0002928_abnormal_bile_duct | 0.75208573 |
68 | MP0008789_abnormal_olfactory_epithelium | 0.72371546 |
69 | MP0002132_abnormal_respiratory_system | 0.71898872 |
70 | MP0000427_abnormal_hair_cycle | 0.71871631 |
71 | MP0003941_abnormal_skin_development | 0.71694402 |
72 | MP0002653_abnormal_ependyma_morphology | 0.71589400 |
73 | MP0005410_abnormal_fertilization | 0.69674772 |
74 | MP0002693_abnormal_pancreas_physiology | 0.68455688 |
75 | MP0002160_abnormal_reproductive_system | 0.68308844 |
76 | MP0002064_seizures | 0.68131089 |
77 | MP0005195_abnormal_posterior_eye | 0.67912998 |
78 | MP0003880_abnormal_central_pattern | 0.66996636 |
79 | MP0009053_abnormal_anal_canal | 0.66836671 |
80 | MP0005452_abnormal_adipose_tissue | 0.66447761 |
81 | MP0001756_abnormal_urination | 0.66420665 |
82 | MP0001873_stomach_inflammation | 0.66222721 |
83 | MP0010094_abnormal_chromosome_stability | 0.64926717 |
84 | MP0005084_abnormal_gallbladder_morpholo | 0.64629342 |
85 | MP0003638_abnormal_response/metabolism_ | 0.64106187 |
86 | MP0001529_abnormal_vocalization | 0.64077329 |
87 | MP0005408_hypopigmentation | 0.63362689 |
88 | MP0000778_abnormal_nervous_system | 0.62398903 |
89 | MP0005220_abnormal_exocrine_pancreas | 0.62214492 |
90 | MP0001324_abnormal_eye_pigmentation | 0.60069727 |
91 | MP0000372_irregular_coat_pigmentation | 0.58603806 |
92 | MP0002752_abnormal_somatic_nervous | 0.58519775 |
93 | MP0002734_abnormal_mechanical_nocicepti | 0.57160671 |
94 | MP0010307_abnormal_tumor_latency | 0.54313498 |
95 | MP0003755_abnormal_palate_morphology | 0.53229604 |
96 | MP0003693_abnormal_embryo_hatching | 0.51998435 |
97 | MP0002066_abnormal_motor_capabilities/c | 0.51902989 |
98 | MP0002557_abnormal_social/conspecific_i | 0.51489065 |
99 | MP0003122_maternal_imprinting | 0.51224766 |
100 | MP0005389_reproductive_system_phenotype | 0.50188238 |
Rank | Gene Set | Z-score |
---|---|---|
1 | 11 pairs of ribs (HP:0000878) | 8.25414216 |
2 | Broad distal phalanx of finger (HP:0009836) | 7.20542899 |
3 | Short nail (HP:0001799) | 6.40602421 |
4 | Radial bowing (HP:0002986) | 5.28587205 |
5 | Spinal cord compression (HP:0002176) | 5.20701590 |
6 | Cupped ribs (HP:0000887) | 4.47128647 |
7 | Irregular vertebral endplates (HP:0003301) | 4.41681402 |
8 | Flared iliac wings (HP:0002869) | 4.39837393 |
9 | Missing ribs (HP:0000921) | 4.28408566 |
10 | Pancreatic fibrosis (HP:0100732) | 3.99996728 |
11 | True hermaphroditism (HP:0010459) | 3.94956482 |
12 | Pancreatic cysts (HP:0001737) | 3.76090109 |
13 | Large for gestational age (HP:0001520) | 3.70569770 |
14 | Short femoral neck (HP:0100864) | 3.65772092 |
15 | Molar tooth sign on MRI (HP:0002419) | 3.62263214 |
16 | Abnormality of midbrain morphology (HP:0002418) | 3.62263214 |
17 | Ovoid vertebral bodies (HP:0003300) | 3.60139296 |
18 | Bicuspid aortic valve (HP:0001647) | 3.54579308 |
19 | Abnormality of the vertebral endplates (HP:0005106) | 3.39971921 |
20 | Congenital, generalized hypertrichosis (HP:0004540) | 3.38969565 |
21 | Mesangial abnormality (HP:0001966) | 3.17765597 |
22 | Slender long bone (HP:0003100) | 3.15741812 |
23 | Furrowed tongue (HP:0000221) | 3.15324793 |
24 | Abnormal vertebral ossification (HP:0100569) | 3.13893784 |
25 | Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108) | 3.13389957 |
26 | Bowing of the arm (HP:0006488) | 3.09417309 |
27 | Bowed forearm bones (HP:0003956) | 3.09417309 |
28 | Fragile skin (HP:0001030) | 3.08041304 |
29 | Genetic anticipation (HP:0003743) | 2.95455275 |
30 | Hypoplastic ischia (HP:0003175) | 2.88377770 |
31 | Coxa valga (HP:0002673) | 2.87289311 |
32 | Abnormality of carpal bone ossification (HP:0006257) | 2.86774722 |
33 | Exostoses (HP:0100777) | 2.86168955 |
34 | Delayed gross motor development (HP:0002194) | 2.82395417 |
35 | Gait imbalance (HP:0002141) | 2.79592278 |
36 | Birth length less than 3rd percentile (HP:0003561) | 2.76824549 |
37 | Sparse scalp hair (HP:0002209) | 2.75037878 |
38 | Congenital stationary night blindness (HP:0007642) | 2.71367467 |
39 | Aplasia/hypoplasia of the femur (HP:0005613) | 2.66616387 |
40 | Congenital primary aphakia (HP:0007707) | 2.66519442 |
41 | Aplasia/Hypoplasia involving the pelvis (HP:0009103) | 2.65705295 |
42 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 2.61444366 |
43 | Cystic liver disease (HP:0006706) | 2.59072235 |
44 | Pendular nystagmus (HP:0012043) | 2.58475861 |
45 | Medial flaring of the eyebrow (HP:0010747) | 2.49982456 |
46 | Hyperventilation (HP:0002883) | 2.49516149 |
47 | Nephrogenic diabetes insipidus (HP:0009806) | 2.48315613 |
48 | Nephronophthisis (HP:0000090) | 2.40728506 |
49 | Soft skin (HP:0000977) | 2.39397109 |
50 | Hyperalaninemia (HP:0003348) | 2.38680069 |
51 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.38680069 |
52 | Abnormality of alanine metabolism (HP:0010916) | 2.38680069 |
53 | Progressive cerebellar ataxia (HP:0002073) | 2.37437721 |
54 | Sclerocornea (HP:0000647) | 2.33980455 |
55 | Metatarsus adductus (HP:0001840) | 2.33088685 |
56 | Male pseudohermaphroditism (HP:0000037) | 2.31894548 |
57 | Abnormality of the ischium (HP:0003174) | 2.30760709 |
58 | Abnormality of the radial head (HP:0003995) | 2.29927017 |
59 | Dislocated radial head (HP:0003083) | 2.29029516 |
60 | Short hallux (HP:0010109) | 2.23297812 |
61 | Carpal synostosis (HP:0009702) | 2.23285966 |
62 | Inability to walk (HP:0002540) | 2.21476065 |
63 | Dyskinesia (HP:0100660) | 2.20531830 |
64 | Broad metatarsal (HP:0001783) | 2.16395630 |
65 | Severe muscular hypotonia (HP:0006829) | 2.12643034 |
66 | Fair hair (HP:0002286) | 2.12623707 |
67 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 2.08492121 |
68 | Methylmalonic acidemia (HP:0002912) | 2.05783629 |
69 | Conical tooth (HP:0000698) | 2.04448996 |
70 | Abnormal hand bone ossification (HP:0010660) | 2.04158071 |
71 | Type II lissencephaly (HP:0007260) | 2.00049456 |
72 | Synostosis involving bones of the hand (HP:0004278) | 1.95705396 |
73 | Anencephaly (HP:0002323) | 1.94699986 |
74 | Patellar aplasia (HP:0006443) | 1.93866935 |
75 | Microretrognathia (HP:0000308) | 1.93693760 |
76 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.92025557 |
77 | Aplastic anemia (HP:0001915) | 1.91149977 |
78 | Aplasia/Hypoplasia of the patella (HP:0006498) | 1.86654607 |
79 | Abolished electroretinogram (ERG) (HP:0000550) | 1.86402180 |
80 | Abnormal ossification of hand bones (HP:0005921) | 1.86332052 |
81 | Left ventricular hypertrophy (HP:0001712) | 1.83928225 |
82 | Vaginal atresia (HP:0000148) | 1.83706593 |
83 | Broad-based gait (HP:0002136) | 1.83681482 |
84 | Hyperglycinuria (HP:0003108) | 1.82390497 |
85 | Hyperglycinemia (HP:0002154) | 1.82269125 |
86 | Diplopia (HP:0000651) | 1.79369846 |
87 | Abnormality of binocular vision (HP:0011514) | 1.79369846 |
88 | Global brain atrophy (HP:0002283) | 1.78159839 |
89 | Genital tract atresia (HP:0001827) | 1.75283206 |
90 | Aganglionic megacolon (HP:0002251) | 1.75045105 |
91 | Cleft eyelid (HP:0000625) | 1.72427922 |
92 | Abnormality of the renal medulla (HP:0100957) | 1.72018829 |
93 | Flat face (HP:0012368) | 1.71574250 |
94 | Keratoconus (HP:0000563) | 1.68047524 |
95 | Increased corneal curvature (HP:0100692) | 1.68047524 |
96 | Albinism (HP:0001022) | 1.67452929 |
97 | Hypoplasia of the ulna (HP:0003022) | 1.67345073 |
98 | Acute encephalopathy (HP:0006846) | 1.67267266 |
99 | Poor coordination (HP:0002370) | 1.65461444 |
100 | Pathologic fracture (HP:0002756) | 1.64852777 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ADRBK2 | 4.73989962 |
2 | NTRK3 | 4.32423295 |
3 | ACVR1B | 4.09950970 |
4 | GRK1 | 3.72738626 |
5 | TLK1 | 3.56961320 |
6 | BMPR1B | 3.48980372 |
7 | NEK1 | 3.00007344 |
8 | MAP3K2 | 2.78960649 |
9 | ZAK | 2.77882733 |
10 | KSR2 | 2.76244564 |
11 | WNK1 | 2.26317160 |
12 | KSR1 | 2.16327232 |
13 | TGFBR1 | 2.10456721 |
14 | TIE1 | 1.97997399 |
15 | RAF1 | 1.97787769 |
16 | FRK | 1.91988123 |
17 | NUAK1 | 1.78567943 |
18 | NEK2 | 1.68360427 |
19 | MKNK2 | 1.47251900 |
20 | PAK6 | 1.46584449 |
21 | MAP4K2 | 1.43568798 |
22 | WNK4 | 1.36142997 |
23 | LIMK1 | 1.27588070 |
24 | PIK3CA | 1.25261387 |
25 | TXK | 1.22718211 |
26 | BCKDK | 1.22189378 |
27 | WNK3 | 1.14577337 |
28 | CDC7 | 1.12820532 |
29 | EPHB2 | 1.10943257 |
30 | VRK1 | 1.10286991 |
31 | CSNK1G3 | 1.09748800 |
32 | MAPK15 | 1.06255165 |
33 | CSNK1G2 | 0.96149195 |
34 | MARK1 | 0.93351465 |
35 | AURKA | 0.91799805 |
36 | CSNK1G1 | 0.90931900 |
37 | MAP2K1 | 0.90556041 |
38 | PRKCH | 0.87585768 |
39 | CSNK1A1L | 0.85351749 |
40 | MAP2K7 | 0.81470361 |
41 | CLK1 | 0.79823479 |
42 | MAP3K9 | 0.78045738 |
43 | PAK3 | 0.76192793 |
44 | MKNK1 | 0.75110069 |
45 | OXSR1 | 0.74862150 |
46 | BUB1 | 0.74672367 |
47 | CDK4 | 0.74566960 |
48 | PRKCG | 0.74491900 |
49 | KDR | 0.73979576 |
50 | DYRK2 | 0.72744609 |
51 | ADRBK1 | 0.72598376 |
52 | VRK2 | 0.69640331 |
53 | MAPK13 | 0.69201392 |
54 | RET | 0.66760229 |
55 | KIT | 0.66396429 |
56 | PLK3 | 0.62204919 |
57 | PRKCQ | 0.60384885 |
58 | MAP3K11 | 0.57814874 |
59 | PDK2 | 0.57745598 |
60 | TNIK | 0.56913667 |
61 | PLK1 | 0.56587861 |
62 | MUSK | 0.54022608 |
63 | ALK | 0.53849467 |
64 | CHEK2 | 0.53449103 |
65 | MET | 0.51627148 |
66 | CSNK1D | 0.50110673 |
67 | FLT3 | 0.47787665 |
68 | DAPK2 | 0.47374558 |
69 | RPS6KA5 | 0.46070344 |
70 | NEK9 | 0.45307058 |
71 | INSRR | 0.43579409 |
72 | MARK2 | 0.41980570 |
73 | MAP3K1 | 0.41947577 |
74 | MST4 | 0.40393956 |
75 | PLK4 | 0.38845771 |
76 | ATR | 0.35577559 |
77 | CAMK2D | 0.35186235 |
78 | PRKCE | 0.34769493 |
79 | PTK2B | 0.34251817 |
80 | MAP3K12 | 0.34105637 |
81 | STK38L | 0.33616540 |
82 | CAMK2A | 0.32602752 |
83 | SIK2 | 0.32096382 |
84 | MINK1 | 0.29814890 |
85 | PINK1 | 0.28753490 |
86 | LCK | 0.28657953 |
87 | CDK5 | 0.28228173 |
88 | STK39 | 0.27637451 |
89 | PBK | 0.26782894 |
90 | MAP3K4 | 0.26617554 |
91 | CSNK1E | 0.26562411 |
92 | CSNK2A1 | 0.25764385 |
93 | PRKCI | 0.25243754 |
94 | SYK | 0.25082925 |
95 | PRKACA | 0.24451937 |
96 | BRSK2 | 0.23689420 |
97 | SGK1 | 0.23565005 |
98 | TESK2 | 0.22832480 |
99 | STK16 | 0.22318539 |
100 | CSNK1A1 | 0.22050595 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Selenocompound metabolism_Homo sapiens_hsa00450 | 6.19807415 |
2 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 4.34106698 |
3 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 3.42971929 |
4 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 3.20900625 |
5 | Phototransduction_Homo sapiens_hsa04744 | 2.74011786 |
6 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 2.69951592 |
7 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.38917713 |
8 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.29620559 |
9 | Parkinsons disease_Homo sapiens_hsa05012 | 1.97533929 |
10 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.90772673 |
11 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.85915499 |
12 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.69917201 |
13 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.66496907 |
14 | Peroxisome_Homo sapiens_hsa04146 | 1.62927278 |
15 | Proteasome_Homo sapiens_hsa03050 | 1.57247703 |
16 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.55646189 |
17 | Ribosome_Homo sapiens_hsa03010 | 1.52827854 |
18 | Protein export_Homo sapiens_hsa03060 | 1.50956452 |
19 | RNA degradation_Homo sapiens_hsa03018 | 1.50472675 |
20 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.48755689 |
21 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.48328856 |
22 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.46047273 |
23 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.45338048 |
24 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.40123836 |
25 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.35919540 |
26 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.31623477 |
27 | Nicotine addiction_Homo sapiens_hsa05033 | 1.31076803 |
28 | Alzheimers disease_Homo sapiens_hsa05010 | 1.30873269 |
29 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.28860462 |
30 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.27276142 |
31 | Homologous recombination_Homo sapiens_hsa03440 | 1.23202585 |
32 | RNA polymerase_Homo sapiens_hsa03020 | 1.22525645 |
33 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.20019405 |
34 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.17938999 |
35 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.16875131 |
36 | Huntingtons disease_Homo sapiens_hsa05016 | 1.14664486 |
37 | Morphine addiction_Homo sapiens_hsa05032 | 1.13014973 |
38 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.01304168 |
39 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.99142742 |
40 | Mineral absorption_Homo sapiens_hsa04978 | 0.98293914 |
41 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.97946748 |
42 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.96736594 |
43 | Basal transcription factors_Homo sapiens_hsa03022 | 0.95199358 |
44 | Mismatch repair_Homo sapiens_hsa03430 | 0.90089469 |
45 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.89799134 |
46 | Insulin secretion_Homo sapiens_hsa04911 | 0.89615339 |
47 | GABAergic synapse_Homo sapiens_hsa04727 | 0.87966757 |
48 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.86300122 |
49 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.83227056 |
50 | ABC transporters_Homo sapiens_hsa02010 | 0.81769714 |
51 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.81066219 |
52 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.79346932 |
53 | Taste transduction_Homo sapiens_hsa04742 | 0.77421605 |
54 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.75372510 |
55 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.73512979 |
56 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.73253945 |
57 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.72217427 |
58 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.71980310 |
59 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.71751397 |
60 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.68699409 |
61 | DNA replication_Homo sapiens_hsa03030 | 0.68225397 |
62 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.67191025 |
63 | Olfactory transduction_Homo sapiens_hsa04740 | 0.64620189 |
64 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.62190884 |
65 | Sulfur relay system_Homo sapiens_hsa04122 | 0.59888302 |
66 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.59710760 |
67 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.56077899 |
68 | Circadian rhythm_Homo sapiens_hsa04710 | 0.55576496 |
69 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.55509289 |
70 | Purine metabolism_Homo sapiens_hsa00230 | 0.54526321 |
71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.52146154 |
72 | Histidine metabolism_Homo sapiens_hsa00340 | 0.52136253 |
73 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.51621003 |
74 | Circadian entrainment_Homo sapiens_hsa04713 | 0.51310923 |
75 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.51120481 |
76 | Retinol metabolism_Homo sapiens_hsa00830 | 0.50252587 |
77 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.48139017 |
78 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.48038857 |
79 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.46964316 |
80 | Spliceosome_Homo sapiens_hsa03040 | 0.46864577 |
81 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.46814514 |
82 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.44921396 |
83 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.43608857 |
84 | Cocaine addiction_Homo sapiens_hsa05030 | 0.43020022 |
85 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.41857883 |
86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.40535095 |
87 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.40141644 |
88 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.39065834 |
89 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.36710198 |
90 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.36593098 |
91 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.36582954 |
92 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.35607084 |
93 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.35146218 |
94 | RNA transport_Homo sapiens_hsa03013 | 0.34786151 |
95 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.33220016 |
96 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.32667627 |
97 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.31336668 |
98 | Salivary secretion_Homo sapiens_hsa04970 | 0.29021739 |
99 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.27438314 |
100 | Bile secretion_Homo sapiens_hsa04976 | 0.22898541 |