

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | viral transcription (GO:0019083) | 7.57806349 |
| 2 | ribosomal small subunit biogenesis (GO:0042274) | 7.43628366 |
| 3 | translational termination (GO:0006415) | 7.16993410 |
| 4 | response to misfolded protein (GO:0051788) | 6.38547744 |
| 5 | translational elongation (GO:0006414) | 6.22804846 |
| 6 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 6.01983812 |
| 7 | protein targeting to ER (GO:0045047) | 5.88926725 |
| 8 | cotranslational protein targeting to membrane (GO:0006613) | 5.87999499 |
| 9 | viral life cycle (GO:0019058) | 5.79118613 |
| 10 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 5.62864802 |
| 11 | protein localization to endoplasmic reticulum (GO:0070972) | 5.46819701 |
| 12 | ribosomal small subunit assembly (GO:0000028) | 5.45831243 |
| 13 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.45431018 |
| 14 | ATP synthesis coupled proton transport (GO:0015986) | 5.45431018 |
| 15 | cellular protein complex disassembly (GO:0043624) | 5.41745898 |
| 16 | L-serine metabolic process (GO:0006563) | 5.36987127 |
| 17 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 5.26336071 |
| 18 | ubiquinone biosynthetic process (GO:0006744) | 5.12041143 |
| 19 | regulation of protein heterodimerization activity (GO:0043497) | 4.86817475 |
| 20 | DNA replication checkpoint (GO:0000076) | 4.84277906 |
| 21 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 4.79111708 |
| 22 | translational initiation (GO:0006413) | 4.61945794 |
| 23 | ubiquinone metabolic process (GO:0006743) | 4.52790636 |
| 24 | ribonucleoprotein complex disassembly (GO:0032988) | 4.49396796 |
| 25 | macromolecular complex disassembly (GO:0032984) | 4.46702401 |
| 26 | protein complex disassembly (GO:0043241) | 4.46496722 |
| 27 | protein neddylation (GO:0045116) | 4.45320071 |
| 28 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.44107330 |
| 29 | S-adenosylmethionine metabolic process (GO:0046500) | 4.34768600 |
| 30 | regulation of catecholamine uptake involved in synaptic transmission (GO:0051940) | 4.25965602 |
| 31 | regulation of dopamine uptake involved in synaptic transmission (GO:0051584) | 4.25965602 |
| 32 | protein complex biogenesis (GO:0070271) | 4.20087795 |
| 33 | quinone biosynthetic process (GO:1901663) | 4.19313430 |
| 34 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.18143362 |
| 35 | NADH dehydrogenase complex assembly (GO:0010257) | 4.18143362 |
| 36 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.18143362 |
| 37 | translation (GO:0006412) | 4.13264803 |
| 38 | protein deneddylation (GO:0000338) | 4.11578745 |
| 39 | cellular response to arsenic-containing substance (GO:0071243) | 4.04490526 |
| 40 | organelle disassembly (GO:1903008) | 4.00282850 |
| 41 | positive regulation of potassium ion transmembrane transporter activity (GO:1901018) | 3.96938989 |
| 42 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.95995235 |
| 43 | protein targeting to membrane (GO:0006612) | 3.94473279 |
| 44 | membrane repolarization during cardiac muscle cell action potential (GO:0086013) | 3.91183360 |
| 45 | regulation of translational elongation (GO:0006448) | 3.83568857 |
| 46 | deoxyribose phosphate biosynthetic process (GO:0046385) | 3.83125421 |
| 47 | 2-deoxyribonucleotide biosynthetic process (GO:0009265) | 3.83125421 |
| 48 | L-methionine biosynthetic process from methylthioadenosine (GO:0019509) | 3.67420573 |
| 49 | respiratory electron transport chain (GO:0022904) | 3.66455511 |
| 50 | electron transport chain (GO:0022900) | 3.60392484 |
| 51 | protein targeting to mitochondrion (GO:0006626) | 3.56430469 |
| 52 | ATP biosynthetic process (GO:0006754) | 3.53238055 |
| 53 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 3.47033360 |
| 54 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 3.46628712 |
| 55 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 3.46431031 |
| 56 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 3.45218746 |
| 57 | cerebral cortex neuron differentiation (GO:0021895) | 3.45167365 |
| 58 | cellular component biogenesis (GO:0044085) | 3.45148838 |
| 59 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.45054472 |
| 60 | membrane repolarization during action potential (GO:0086011) | 3.43203699 |
| 61 | protein heterotetramerization (GO:0051290) | 3.37776696 |
| 62 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 3.31972198 |
| 63 | positive regulation of skeletal muscle tissue development (GO:0048643) | 3.30404357 |
| 64 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.29558043 |
| 65 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.29558043 |
| 66 | hypothalamus development (GO:0021854) | 3.27782506 |
| 67 | GTP biosynthetic process (GO:0006183) | 3.25699128 |
| 68 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 3.25318706 |
| 69 | respiratory system process (GO:0003016) | 3.24925977 |
| 70 | mRNA catabolic process (GO:0006402) | 3.24360005 |
| 71 | establishment of protein localization to mitochondrion (GO:0072655) | 3.22087470 |
| 72 | nonmotile primary cilium assembly (GO:0035058) | 3.17100535 |
| 73 | guanosine-containing compound biosynthetic process (GO:1901070) | 3.15945907 |
| 74 | regulation of neurotransmitter uptake (GO:0051580) | 3.15195616 |
| 75 | pyrimidine deoxyribonucleotide metabolic process (GO:0009219) | 3.12851825 |
| 76 | serine family amino acid biosynthetic process (GO:0009070) | 3.11984760 |
| 77 | ear development (GO:0043583) | 3.10951435 |
| 78 | protein localization to mitochondrion (GO:0070585) | 3.10401761 |
| 79 | misfolded or incompletely synthesized protein catabolic process (GO:0006515) | 3.09518920 |
| 80 | rRNA processing (GO:0006364) | 3.07938330 |
| 81 | UTP biosynthetic process (GO:0006228) | 3.06960695 |
| 82 | L-methionine biosynthetic process (GO:0071265) | 3.06264403 |
| 83 | amino acid salvage (GO:0043102) | 3.06264403 |
| 84 | L-methionine salvage (GO:0071267) | 3.06264403 |
| 85 | face development (GO:0060324) | 3.05624480 |
| 86 | ribosomal large subunit biogenesis (GO:0042273) | 3.03474636 |
| 87 | positive regulation of hair follicle development (GO:0051798) | 3.02242170 |
| 88 | positive regulation of hair cycle (GO:0042635) | 3.02242170 |
| 89 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.01378826 |
| 90 | mitochondrion transport along microtubule (GO:0047497) | 3.01000466 |
| 91 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 3.01000466 |
| 92 | polarized epithelial cell differentiation (GO:0030859) | 2.98570901 |
| 93 | rRNA metabolic process (GO:0016072) | 2.96430536 |
| 94 | cytochrome complex assembly (GO:0017004) | 2.93316970 |
| 95 | RNA catabolic process (GO:0006401) | 2.92714328 |
| 96 | establishment of monopolar cell polarity (GO:0061162) | 2.92273560 |
| 97 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.92273560 |
| 98 | respiratory chain complex IV assembly (GO:0008535) | 2.92178167 |
| 99 | maturation of SSU-rRNA (GO:0030490) | 13.5967565 |
| 100 | chaperone-mediated protein transport (GO:0072321) | 10.6059575 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 4.87291522 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 3.65768103 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.64363998 |
| 4 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.40979548 |
| 5 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.20104126 |
| 6 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 3.07183578 |
| 7 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 3.04568974 |
| 8 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 2.96596741 |
| 9 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 2.92762840 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 2.88099217 |
| 11 | XRN2_22483619_ChIP-Seq_HELA_Human | 2.63549960 |
| 12 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 2.48177648 |
| 13 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.44906395 |
| 14 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.41934779 |
| 15 | TTF2_22483619_ChIP-Seq_HELA_Human | 2.37442214 |
| 16 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.29660668 |
| 17 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 2.27345625 |
| 18 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.23275683 |
| 19 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.18280119 |
| 20 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.06111157 |
| 21 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.96955750 |
| 22 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.94315249 |
| 23 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 1.91036662 |
| 24 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.89647900 |
| 25 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.89492926 |
| 26 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.86530665 |
| 27 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.78375617 |
| 28 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.77097502 |
| 29 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.76358882 |
| 30 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.74031049 |
| 31 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.73491173 |
| 32 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.72693258 |
| 33 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.70583324 |
| 34 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 1.69476777 |
| 35 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.67595193 |
| 36 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.62421412 |
| 37 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.61474256 |
| 38 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.60287470 |
| 39 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.60196629 |
| 40 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.58989384 |
| 41 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.57400345 |
| 42 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.56874414 |
| 43 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.50297583 |
| 44 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.47448628 |
| 45 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.45922237 |
| 46 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.42439128 |
| 47 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.40657439 |
| 48 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.39637864 |
| 49 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 1.39210667 |
| 50 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.37096405 |
| 51 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.35768890 |
| 52 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25334622 |
| 53 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.24339601 |
| 54 | EWS_26573619_Chip-Seq_HEK293_Human | 1.21924714 |
| 55 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.19871852 |
| 56 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.19871852 |
| 57 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.17435229 |
| 58 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.17001595 |
| 59 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.16779722 |
| 60 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 1.16065943 |
| 61 | HTT_18923047_ChIP-ChIP_STHdh_Human | 1.15272052 |
| 62 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.14973893 |
| 63 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12892209 |
| 64 | SIN3A_21632747_ChIP-Seq_MESCs_Mouse | 1.11951733 |
| 65 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.11070003 |
| 66 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.11063692 |
| 67 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.10613943 |
| 68 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.10327228 |
| 69 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.09938058 |
| 70 | CNOT3_19339689_ChIP-ChIP_MESCs_Mouse | 1.09025015 |
| 71 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.08966726 |
| 72 | NCOR_22424771_ChIP-Seq_293T_Human | 1.05556939 |
| 73 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.04002973 |
| 74 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.02589600 |
| 75 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.00402172 |
| 76 | CTCF_26484167_Chip-Seq_Bcells_Mouse | 0.99956453 |
| 77 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.99439998 |
| 78 | ERA_21632823_ChIP-Seq_H3396_Human | 0.98007666 |
| 79 | TP63_19390658_ChIP-ChIP_HaCaT_Human | 0.97910641 |
| 80 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.97678060 |
| 81 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.97030721 |
| 82 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.94897603 |
| 83 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 0.94402300 |
| 84 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 0.92826822 |
| 85 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.91937443 |
| 86 | REST_19997604_ChIP-ChIP_NEURONS_Mouse | 0.89767705 |
| 87 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.89246700 |
| 88 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 0.88439467 |
| 89 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.88439467 |
| 90 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 0.88439467 |
| 91 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 0.87970196 |
| 92 | ELF1_20517297_ChIP-Seq_JURKAT_Human | 0.86164623 |
| 93 | P68_20966046_ChIP-Seq_HELA_Human | 0.85837166 |
| 94 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.85716307 |
| 95 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 0.85406320 |
| 96 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 0.84929803 |
| 97 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.84749737 |
| 98 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.84528416 |
| 99 | SETDB1_19884257_ChIP-Seq_MESCs_Mouse | 0.83153613 |
| 100 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 0.82446407 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002163_abnormal_gland_morphology | 4.66865885 |
| 2 | MP0009379_abnormal_foot_pigmentation | 3.94132296 |
| 3 | MP0001529_abnormal_vocalization | 3.33125299 |
| 4 | MP0006292_abnormal_olfactory_placode | 3.24676491 |
| 5 | MP0005379_endocrine/exocrine_gland_phen | 3.14391596 |
| 6 | MP0004858_abnormal_nervous_system | 2.98215173 |
| 7 | MP0004885_abnormal_endolymph | 2.93241178 |
| 8 | MP0003136_yellow_coat_color | 2.31944378 |
| 9 | MP0000631_abnormal_neuroendocrine_gland | 2.31225257 |
| 10 | MP0010030_abnormal_orbit_morphology | 2.26874138 |
| 11 | MP0009053_abnormal_anal_canal | 2.22404952 |
| 12 | MP0000537_abnormal_urethra_morphology | 2.22359056 |
| 13 | MP0000566_synostosis | 2.18762281 |
| 14 | MP0004145_abnormal_muscle_electrophysio | 2.18125922 |
| 15 | MP0005646_abnormal_pituitary_gland | 2.16958239 |
| 16 | MP0008260_abnormal_autophagy | 2.05964606 |
| 17 | MP0003941_abnormal_skin_development | 2.02273340 |
| 18 | MP0005423_abnormal_somatic_nervous | 1.99799645 |
| 19 | MP0001348_abnormal_lacrimal_gland | 1.99037283 |
| 20 | MP0003123_paternal_imprinting | 1.96433521 |
| 21 | MP0006035_abnormal_mitochondrial_morpho | 1.84091108 |
| 22 | MP0006036_abnormal_mitochondrial_physio | 1.83905386 |
| 23 | MP0005083_abnormal_biliary_tract | 1.81390074 |
| 24 | MP0002234_abnormal_pharynx_morphology | 1.80604525 |
| 25 | MP0000049_abnormal_middle_ear | 1.72752997 |
| 26 | MP0002160_abnormal_reproductive_system | 1.63020339 |
| 27 | MP0003315_abnormal_perineum_morphology | 1.62017653 |
| 28 | MP0000778_abnormal_nervous_system | 1.61809370 |
| 29 | MP0002277_abnormal_respiratory_mucosa | 1.58103365 |
| 30 | MP0000678_abnormal_parathyroid_gland | 1.51757365 |
| 31 | MP0004142_abnormal_muscle_tone | 1.51689879 |
| 32 | MP0002653_abnormal_ependyma_morphology | 1.49040946 |
| 33 | MP0003567_abnormal_fetal_cardiomyocyte | 1.43598801 |
| 34 | MP0003786_premature_aging | 1.43276844 |
| 35 | MP0000428_abnormal_craniofacial_morphol | 1.41079002 |
| 36 | MP0005187_abnormal_penis_morphology | 1.39993558 |
| 37 | MP0001905_abnormal_dopamine_level | 1.37254319 |
| 38 | MP0003879_abnormal_hair_cell | 1.36702348 |
| 39 | MP0002938_white_spotting | 1.36607837 |
| 40 | MP0003122_maternal_imprinting | 1.35639183 |
| 41 | MP0001293_anophthalmia | 1.34086374 |
| 42 | MP0003646_muscle_fatigue | 1.32424993 |
| 43 | MP0001299_abnormal_eye_distance/ | 1.31684251 |
| 44 | MP0001346_abnormal_lacrimal_gland | 1.27198836 |
| 45 | MP0002638_abnormal_pupillary_reflex | 1.25670660 |
| 46 | MP0005360_urolithiasis | 1.21444454 |
| 47 | MP0003942_abnormal_urinary_system | 1.20170793 |
| 48 | MP0004147_increased_porphyrin_level | 1.16255404 |
| 49 | MP0009046_muscle_twitch | 1.15885797 |
| 50 | MP0003186_abnormal_redox_activity | 1.15455945 |
| 51 | MP0002249_abnormal_larynx_morphology | 1.15101128 |
| 52 | MP0005386_behavior/neurological_phenoty | 1.14198682 |
| 53 | MP0004924_abnormal_behavior | 1.14198682 |
| 54 | MP0002095_abnormal_skin_pigmentation | 1.14099174 |
| 55 | MP0002837_dystrophic_cardiac_calcinosis | 1.11548843 |
| 56 | MP0009250_abnormal_appendicular_skeleto | 1.09522715 |
| 57 | MP0005389_reproductive_system_phenotype | 1.06868938 |
| 58 | MP0006276_abnormal_autonomic_nervous | 1.06755148 |
| 59 | MP0003283_abnormal_digestive_organ | 1.04896236 |
| 60 | MP0000647_abnormal_sebaceous_gland | 1.03727414 |
| 61 | MP0000026_abnormal_inner_ear | 1.03376468 |
| 62 | MP0003119_abnormal_digestive_system | 1.02231895 |
| 63 | MP0003221_abnormal_cardiomyocyte_apopto | 0.99892984 |
| 64 | MP0009745_abnormal_behavioral_response | 0.92561619 |
| 65 | MP0005084_abnormal_gallbladder_morpholo | 0.91274611 |
| 66 | MP0008932_abnormal_embryonic_tissue | 0.90935384 |
| 67 | MP0001963_abnormal_hearing_physiology | 0.90851507 |
| 68 | MP0002177_abnormal_outer_ear | 0.89739009 |
| 69 | MP0005551_abnormal_eye_electrophysiolog | 0.87816190 |
| 70 | MP0002282_abnormal_trachea_morphology | 0.87456848 |
| 71 | MP0008789_abnormal_olfactory_epithelium | 0.87342778 |
| 72 | MP0002210_abnormal_sex_determination | 0.86488228 |
| 73 | MP0001286_abnormal_eye_development | 0.86294393 |
| 74 | MP0002233_abnormal_nose_morphology | 0.85528866 |
| 75 | MP0003938_abnormal_ear_development | 0.85393325 |
| 76 | MP0002116_abnormal_craniofacial_bone | 0.83638544 |
| 77 | MP0003693_abnormal_embryo_hatching | 0.83291307 |
| 78 | MP0000955_abnormal_spinal_cord | 0.79809370 |
| 79 | MP0002932_abnormal_joint_morphology | 0.79139519 |
| 80 | MP0003011_delayed_dark_adaptation | 0.78598031 |
| 81 | MP0002064_seizures | 0.78552864 |
| 82 | MP0002736_abnormal_nociception_after | 0.75675468 |
| 83 | MP0002557_abnormal_social/conspecific_i | 0.75359159 |
| 84 | MP0008058_abnormal_DNA_repair | 0.74421448 |
| 85 | MP0003806_abnormal_nucleotide_metabolis | 0.74298628 |
| 86 | MP0008877_abnormal_DNA_methylation | 0.72694544 |
| 87 | MP0002733_abnormal_thermal_nociception | 0.72558858 |
| 88 | MP0009780_abnormal_chondrocyte_physiolo | 0.71638603 |
| 89 | MP0003385_abnormal_body_wall | 0.71066767 |
| 90 | MP0003755_abnormal_palate_morphology | 0.69683619 |
| 91 | MP0001340_abnormal_eyelid_morphology | 0.69239622 |
| 92 | MP0003937_abnormal_limbs/digits/tail_de | 0.68122966 |
| 93 | MP0000343_altered_response_to | 0.66915035 |
| 94 | MP0000653_abnormal_sex_gland | 0.66529156 |
| 95 | MP0002132_abnormal_respiratory_system | 0.65726580 |
| 96 | MP0009764_decreased_sensitivity_to | 0.64344617 |
| 97 | MP0004130_abnormal_muscle_cell | 0.62341642 |
| 98 | MP0002752_abnormal_somatic_nervous | 0.62305705 |
| 99 | MP0003121_genomic_imprinting | 0.60335455 |
| 100 | MP0000516_abnormal_urinary_system | 0.59744222 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Septo-optic dysplasia (HP:0100842) | 5.18539779 |
| 2 | Macrocytic anemia (HP:0001972) | 4.82528903 |
| 3 | 3-Methylglutaconic aciduria (HP:0003535) | 4.53499928 |
| 4 | Reticulocytopenia (HP:0001896) | 4.50328485 |
| 5 | Lipid accumulation in hepatocytes (HP:0006561) | 4.28905974 |
| 6 | Acute necrotizing encephalopathy (HP:0006965) | 4.16517419 |
| 7 | Abnormal mitochondria in muscle tissue (HP:0008316) | 3.75858203 |
| 8 | Increased hepatocellular lipid droplets (HP:0006565) | 3.67600827 |
| 9 | Increased serum lactate (HP:0002151) | 3.65828719 |
| 10 | Mitochondrial inheritance (HP:0001427) | 3.62889281 |
| 11 | Increased muscle lipid content (HP:0009058) | 3.58494178 |
| 12 | Acute encephalopathy (HP:0006846) | 3.51328624 |
| 13 | Increased intramyocellular lipid droplets (HP:0012240) | 3.49805667 |
| 14 | Abnormality of lateral ventricle (HP:0030047) | 3.43677544 |
| 15 | Increased CSF lactate (HP:0002490) | 3.31404285 |
| 16 | Maternal diabetes (HP:0009800) | 3.31289698 |
| 17 | Progressive macrocephaly (HP:0004481) | 3.31185663 |
| 18 | Renal Fanconi syndrome (HP:0001994) | 3.27227954 |
| 19 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 3.22034117 |
| 20 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 3.22034117 |
| 21 | Medial flaring of the eyebrow (HP:0010747) | 3.15337931 |
| 22 | Coronal craniosynostosis (HP:0004440) | 3.11925822 |
| 23 | Gait imbalance (HP:0002141) | 3.08570346 |
| 24 | Absent septum pellucidum (HP:0001331) | 2.99281973 |
| 25 | Respiratory difficulties (HP:0002880) | 2.95777567 |
| 26 | Congenital primary aphakia (HP:0007707) | 2.87280568 |
| 27 | Pallor (HP:0000980) | 2.85144953 |
| 28 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.81344160 |
| 29 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.79299465 |
| 30 | Exertional dyspnea (HP:0002875) | 2.76824480 |
| 31 | Vaginal atresia (HP:0000148) | 2.76578406 |
| 32 | Genital tract atresia (HP:0001827) | 2.75605303 |
| 33 | Increased serum pyruvate (HP:0003542) | 2.68161471 |
| 34 | Abnormality of alanine metabolism (HP:0010916) | 2.65609475 |
| 35 | Hyperalaninemia (HP:0003348) | 2.65609475 |
| 36 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.65609475 |
| 37 | Lactic acidosis (HP:0003128) | 2.59672913 |
| 38 | Poor coordination (HP:0002370) | 2.53618251 |
| 39 | Hepatocellular necrosis (HP:0001404) | 2.52661476 |
| 40 | Abnormality of cochlea (HP:0000375) | 2.52433744 |
| 41 | Abnormal number of erythroid precursors (HP:0012131) | 2.50648093 |
| 42 | Turricephaly (HP:0000262) | 2.50520560 |
| 43 | Optic nerve hypoplasia (HP:0000609) | 2.49896052 |
| 44 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 2.48269286 |
| 45 | Abnormality of the septum pellucidum (HP:0007375) | 2.46209374 |
| 46 | Delayed CNS myelination (HP:0002188) | 2.43010725 |
| 47 | Nephrogenic diabetes insipidus (HP:0009806) | 2.41738362 |
| 48 | Rib fusion (HP:0000902) | 2.40755170 |
| 49 | Status epilepticus (HP:0002133) | 2.39759921 |
| 50 | Congenital stationary night blindness (HP:0007642) | 2.35107162 |
| 51 | Poor suck (HP:0002033) | 2.32280222 |
| 52 | True hermaphroditism (HP:0010459) | 2.30944673 |
| 53 | Pancreatic fibrosis (HP:0100732) | 2.30819159 |
| 54 | Myokymia (HP:0002411) | 2.27606231 |
| 55 | Cleft eyelid (HP:0000625) | 2.26425613 |
| 56 | Progressive microcephaly (HP:0000253) | 2.22785331 |
| 57 | Adrenal hypoplasia (HP:0000835) | 2.17261379 |
| 58 | Cerebral edema (HP:0002181) | 2.17097818 |
| 59 | Hepatic necrosis (HP:0002605) | 2.16943266 |
| 60 | Abnormality of the parietal bone (HP:0002696) | 2.15787373 |
| 61 | Exercise intolerance (HP:0003546) | 2.15056193 |
| 62 | Pancreatic cysts (HP:0001737) | 2.14231090 |
| 63 | Absent thumb (HP:0009777) | 2.12003346 |
| 64 | Cortical visual impairment (HP:0100704) | 2.11939007 |
| 65 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.09879247 |
| 66 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.09310242 |
| 67 | Birth length less than 3rd percentile (HP:0003561) | 2.09131335 |
| 68 | Sensory axonal neuropathy (HP:0003390) | 2.07959123 |
| 69 | Abnormality of renal resorption (HP:0011038) | 2.06929140 |
| 70 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.03615895 |
| 71 | Absent/shortened dynein arms (HP:0200106) | 2.03615895 |
| 72 | Abnormal rod and cone electroretinograms (HP:0008323) | 2.01998950 |
| 73 | Absent eyebrow (HP:0002223) | 1.98115524 |
| 74 | Respiratory failure (HP:0002878) | 1.96001622 |
| 75 | Long foot (HP:0001833) | 1.95437533 |
| 76 | Wide intermamillary distance (HP:0006610) | 1.92169253 |
| 77 | Bilateral microphthalmos (HP:0007633) | 1.89637231 |
| 78 | Polycystic ovaries (HP:0000147) | 1.86251477 |
| 79 | Abnormality of the phalanges of the hallux (HP:0010057) | 1.86181660 |
| 80 | Leukodystrophy (HP:0002415) | 1.86093762 |
| 81 | Myotonia (HP:0002486) | 1.85517997 |
| 82 | Specific learning disability (HP:0001328) | 1.85085771 |
| 83 | Morphological abnormality of the inner ear (HP:0011390) | 1.84768053 |
| 84 | Hyperglycinemia (HP:0002154) | 1.84192556 |
| 85 | Abnormality of glycolysis (HP:0004366) | 1.82916611 |
| 86 | Triphalangeal thumb (HP:0001199) | 1.78710256 |
| 87 | Hyperventilation (HP:0002883) | 1.73893217 |
| 88 | Partial duplication of the phalanx of hand (HP:0009999) | 1.73677511 |
| 89 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.71905085 |
| 90 | Broad hallux (HP:0010055) | 1.71092361 |
| 91 | Anophthalmia (HP:0000528) | 1.70705152 |
| 92 | Hyperphosphaturia (HP:0003109) | 1.70627322 |
| 93 | Lethargy (HP:0001254) | 1.67202171 |
| 94 | Growth hormone deficiency (HP:0000824) | 1.66428966 |
| 95 | Overriding aorta (HP:0002623) | 1.65335879 |
| 96 | Abnormal ciliary motility (HP:0012262) | 1.63486730 |
| 97 | Abnormality of the middle phalanges of the toes (HP:0010183) | 1.63370141 |
| 98 | Glycosuria (HP:0003076) | 1.62826624 |
| 99 | Abnormality of urine glucose concentration (HP:0011016) | 1.62826624 |
| 100 | Morphological abnormality of the middle ear (HP:0008609) | 1.61708731 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | STK16 | 4.94941265 |
| 2 | NME2 | 4.33246607 |
| 3 | EPHB2 | 4.08635179 |
| 4 | PLK2 | 3.65152111 |
| 5 | PRKD3 | 3.16945296 |
| 6 | STK3 | 2.85892681 |
| 7 | WNK4 | 2.76264152 |
| 8 | GRK1 | 2.48730574 |
| 9 | PIK3CA | 2.28908595 |
| 10 | PAK6 | 2.16286862 |
| 11 | BUB1 | 1.96926095 |
| 12 | PASK | 1.66497819 |
| 13 | ERBB2 | 1.60381010 |
| 14 | BMPR1B | 1.58968564 |
| 15 | RPS6KA4 | 1.54463201 |
| 16 | DYRK2 | 1.53321820 |
| 17 | PIM2 | 1.51710765 |
| 18 | PDK2 | 1.47733338 |
| 19 | TNIK | 1.45983798 |
| 20 | PLK3 | 1.41595003 |
| 21 | ADRBK2 | 1.35165891 |
| 22 | PNCK | 1.30429789 |
| 23 | CAMK1G | 1.24832710 |
| 24 | LATS1 | 1.20722132 |
| 25 | MAPK13 | 1.18116149 |
| 26 | CCNB1 | 1.17899116 |
| 27 | DMPK | 1.15876131 |
| 28 | RPS6KA5 | 1.15390720 |
| 29 | CSNK2A2 | 1.05633013 |
| 30 | LRRK2 | 1.03133991 |
| 31 | CSNK1A1 | 0.98279719 |
| 32 | ABL2 | 0.98077852 |
| 33 | NEK1 | 0.97431872 |
| 34 | PAK2 | 0.96533379 |
| 35 | ZAK | 0.95673541 |
| 36 | TYK2 | 0.92797729 |
| 37 | CAMKK2 | 0.92522861 |
| 38 | TRIM28 | 0.92009653 |
| 39 | MAP2K6 | 0.89593682 |
| 40 | DYRK3 | 0.85666402 |
| 41 | MARK1 | 0.83661061 |
| 42 | CDK14 | 0.82515503 |
| 43 | CSNK2A1 | 0.82322118 |
| 44 | AURKB | 0.80006296 |
| 45 | MOS | 0.78890900 |
| 46 | CAMK1D | 0.76496338 |
| 47 | CAMK2A | 0.76444253 |
| 48 | TGFBR1 | 0.74278177 |
| 49 | CAMK1 | 0.73857485 |
| 50 | ATR | 0.73548636 |
| 51 | PRKCQ | 0.72495641 |
| 52 | PINK1 | 0.69813198 |
| 53 | MARK3 | 0.69370543 |
| 54 | IKBKB | 0.68156421 |
| 55 | EIF2AK2 | 0.65734079 |
| 56 | KIT | 0.65694530 |
| 57 | SGK1 | 0.65021419 |
| 58 | PRKG1 | 0.64158148 |
| 59 | PRKCI | 0.62889225 |
| 60 | INSRR | 0.62206166 |
| 61 | CSNK1G2 | 0.62201996 |
| 62 | PRKG2 | 0.61347152 |
| 63 | PRKCZ | 0.61158834 |
| 64 | WNK1 | 0.60682233 |
| 65 | TLK1 | 0.58211796 |
| 66 | CSNK1G3 | 0.57739280 |
| 67 | OBSCN | 0.56862223 |
| 68 | PLK1 | 0.53319237 |
| 69 | NUAK1 | 0.52999403 |
| 70 | PRKCG | 0.52980697 |
| 71 | TEC | 0.52812506 |
| 72 | PRKACA | 0.51721568 |
| 73 | MAPK15 | 0.51102873 |
| 74 | PAK1 | 0.50883035 |
| 75 | PAK3 | 0.50807132 |
| 76 | CHEK2 | 0.49880090 |
| 77 | IRAK4 | 0.49552487 |
| 78 | AKT1 | 0.48081530 |
| 79 | TXK | 0.48049975 |
| 80 | CAMKK1 | 0.47573275 |
| 81 | PHKG2 | 0.46527127 |
| 82 | PHKG1 | 0.46527127 |
| 83 | RPS6KA2 | 0.46248781 |
| 84 | PRKCA | 0.46185803 |
| 85 | DAPK2 | 0.45700558 |
| 86 | STK11 | 0.45509603 |
| 87 | RPS6KA6 | 0.44743057 |
| 88 | IRAK3 | 0.44480925 |
| 89 | UHMK1 | 0.44463624 |
| 90 | PRKCD | 0.42951458 |
| 91 | PLK4 | 0.42296293 |
| 92 | CSNK1E | 0.40798078 |
| 93 | IKBKE | 0.39010444 |
| 94 | FRK | 0.36312445 |
| 95 | PDGFRB | 0.36017900 |
| 96 | MINK1 | 0.35925990 |
| 97 | RPS6KA3 | 0.35161031 |
| 98 | PRKCE | 0.34868206 |
| 99 | PRKACB | 0.34468607 |
| 100 | PRKDC | 0.33703749 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Ribosome_Homo sapiens_hsa03010 | 7.54032150 |
| 2 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 4.17902257 |
| 3 | Parkinsons disease_Homo sapiens_hsa05012 | 3.55839733 |
| 4 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.32439304 |
| 5 | Sulfur relay system_Homo sapiens_hsa04122 | 2.84816270 |
| 6 | Huntingtons disease_Homo sapiens_hsa05016 | 2.68394578 |
| 7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.59919433 |
| 8 | RNA polymerase_Homo sapiens_hsa03020 | 2.57842277 |
| 9 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 2.42993150 |
| 10 | Alzheimers disease_Homo sapiens_hsa05010 | 2.37028352 |
| 11 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.19580763 |
| 12 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 2.02251134 |
| 13 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.66393333 |
| 14 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.65819631 |
| 15 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.65194682 |
| 16 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.52043412 |
| 17 | Proteasome_Homo sapiens_hsa03050 | 1.49234593 |
| 18 | Protein export_Homo sapiens_hsa03060 | 1.43952216 |
| 19 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.40456839 |
| 20 | DNA replication_Homo sapiens_hsa03030 | 1.35911694 |
| 21 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.33849819 |
| 22 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.31874395 |
| 23 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.31213918 |
| 24 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.25839049 |
| 25 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.20516607 |
| 26 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.18876534 |
| 27 | Homologous recombination_Homo sapiens_hsa03440 | 1.18520134 |
| 28 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.17709710 |
| 29 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.16623714 |
| 30 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.15530877 |
| 31 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.15117829 |
| 32 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.15066129 |
| 33 | Phototransduction_Homo sapiens_hsa04744 | 1.13873214 |
| 34 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.10653092 |
| 35 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.03768999 |
| 36 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.02299995 |
| 37 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.00762482 |
| 38 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.96774925 |
| 39 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.94121929 |
| 40 | RNA degradation_Homo sapiens_hsa03018 | 0.89325858 |
| 41 | Retinol metabolism_Homo sapiens_hsa00830 | 0.89135737 |
| 42 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.88466960 |
| 43 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.87015900 |
| 44 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.84269925 |
| 45 | Basal transcription factors_Homo sapiens_hsa03022 | 0.83462011 |
| 46 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.82845112 |
| 47 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.82426853 |
| 48 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.80451909 |
| 49 | Spliceosome_Homo sapiens_hsa03040 | 0.79363084 |
| 50 | Metabolic pathways_Homo sapiens_hsa01100 | 0.76440739 |
| 51 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.74976787 |
| 52 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.74903011 |
| 53 | Purine metabolism_Homo sapiens_hsa00230 | 0.71640395 |
| 54 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 0.70261156 |
| 55 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.67740575 |
| 56 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.66147931 |
| 57 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.64825387 |
| 58 | Lysine degradation_Homo sapiens_hsa00310 | 0.63183903 |
| 59 | RNA transport_Homo sapiens_hsa03013 | 0.63035450 |
| 60 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.62743111 |
| 61 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.61211771 |
| 62 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.58439166 |
| 63 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.55910992 |
| 64 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.54455960 |
| 65 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.52514304 |
| 66 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.47561594 |
| 67 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.47441323 |
| 68 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.46480259 |
| 69 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.44820626 |
| 70 | Olfactory transduction_Homo sapiens_hsa04740 | 0.43044284 |
| 71 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.42968151 |
| 72 | Peroxisome_Homo sapiens_hsa04146 | 0.42437313 |
| 73 | Nicotine addiction_Homo sapiens_hsa05033 | 0.39087535 |
| 74 | Cell cycle_Homo sapiens_hsa04110 | 0.38577741 |
| 75 | Asthma_Homo sapiens_hsa05310 | 0.38507879 |
| 76 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.38399017 |
| 77 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.38365421 |
| 78 | Base excision repair_Homo sapiens_hsa03410 | 0.38296400 |
| 79 | Mismatch repair_Homo sapiens_hsa03430 | 0.37217877 |
| 80 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.36589531 |
| 81 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.35750427 |
| 82 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.34805102 |
| 83 | Mineral absorption_Homo sapiens_hsa04978 | 0.33108885 |
| 84 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.32322996 |
| 85 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.32310605 |
| 86 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.31581904 |
| 87 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.31361634 |
| 88 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.30983599 |
| 89 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.29786701 |
| 90 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.29022380 |
| 91 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.28748053 |
| 92 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.26315542 |
| 93 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.25317833 |
| 94 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.23689930 |
| 95 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.19962317 |
| 96 | Butanoate metabolism_Homo sapiens_hsa00650 | 0.19924137 |
| 97 | ABC transporters_Homo sapiens_hsa02010 | 0.19606321 |
| 98 | Insulin secretion_Homo sapiens_hsa04911 | 0.17564559 |
| 99 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.16706525 |
| 100 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.16159158 |

