

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | response to gravity (GO:0009629) | 9.44118571 |
| 2 | growth hormone secretion (GO:0030252) | 7.26310959 |
| 3 | ganglion development (GO:0061548) | 6.98296862 |
| 4 | skeletal muscle adaptation (GO:0043501) | 6.26183752 |
| 5 | muscle atrophy (GO:0014889) | 6.14745147 |
| 6 | striated muscle atrophy (GO:0014891) | 6.04485200 |
| 7 | negative regulation of muscle hypertrophy (GO:0014741) | 5.82936866 |
| 8 | regulation of skeletal muscle contraction (GO:0014819) | 5.57981037 |
| 9 | response to folic acid (GO:0051593) | 5.11500052 |
| 10 | skeletal muscle tissue regeneration (GO:0043403) | 4.92621087 |
| 11 | negative regulation of endoplasmic reticulum calcium ion concentration (GO:0032471) | 4.79037827 |
| 12 | actin-myosin filament sliding (GO:0033275) | 4.75264819 |
| 13 | muscle filament sliding (GO:0030049) | 4.75264819 |
| 14 | regulation of transcription involved in cell fate commitment (GO:0060850) | 4.74678767 |
| 15 | galactose catabolic process (GO:0019388) | 4.67484691 |
| 16 | galactose metabolic process (GO:0006012) | 4.66173913 |
| 17 | positive regulation of endothelial cell differentiation (GO:0045603) | 4.55743432 |
| 18 | regulation of timing of cell differentiation (GO:0048505) | 4.54683198 |
| 19 | purine nucleotide salvage (GO:0032261) | 4.38689776 |
| 20 | positive regulation of growth hormone secretion (GO:0060124) | 4.38288393 |
| 21 | cerebral cortex neuron differentiation (GO:0021895) | 4.37014712 |
| 22 | negative regulation of catenin import into nucleus (GO:0035414) | 4.34735014 |
| 23 | spinal cord association neuron differentiation (GO:0021527) | 4.32215830 |
| 24 | response to muscle activity (GO:0014850) | 4.30936780 |
| 25 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.28362854 |
| 26 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.28362854 |
| 27 | lung secretory cell differentiation (GO:0061140) | 4.24976079 |
| 28 | secondary heart field specification (GO:0003139) | 4.14266636 |
| 29 | heart field specification (GO:0003128) | 4.14266636 |
| 30 | negative regulation of oligodendrocyte differentiation (GO:0048715) | 4.12463984 |
| 31 | negative regulation of skeletal muscle tissue development (GO:0048642) | 4.08354349 |
| 32 | auditory behavior (GO:0031223) | 3.94895148 |
| 33 | protein retention in ER lumen (GO:0006621) | 3.93477813 |
| 34 | positive regulation of actin filament depolymerization (GO:0030836) | 3.91938707 |
| 35 | epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198) | 3.89384084 |
| 36 | microtubule nucleation (GO:0007020) | 3.88298352 |
| 37 | regulation of development, heterochronic (GO:0040034) | 3.85364662 |
| 38 | actin-mediated cell contraction (GO:0070252) | 3.84574820 |
| 39 | protein maturation by protein folding (GO:0022417) | 3.73249932 |
| 40 | regulation of plasminogen activation (GO:0010755) | 3.67532564 |
| 41 | alternative mRNA splicing, via spliceosome (GO:0000380) | 3.66730476 |
| 42 | multicellular organismal movement (GO:0050879) | 3.60985478 |
| 43 | musculoskeletal movement (GO:0050881) | 3.60985478 |
| 44 | mesenchymal cell differentiation involved in renal system development (GO:2001012) | 3.58248965 |
| 45 | mesenchymal cell differentiation involved in kidney development (GO:0072161) | 3.58248965 |
| 46 | adenosine metabolic process (GO:0046085) | 3.46908011 |
| 47 | negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518) | 3.45824101 |
| 48 | postsynaptic membrane organization (GO:0001941) | 3.41827349 |
| 49 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 3.40472788 |
| 50 | mesonephros development (GO:0001823) | 3.38839335 |
| 51 | desmosome organization (GO:0002934) | 3.35281335 |
| 52 | regulation of branching involved in salivary gland morphogenesis (GO:0060693) | 3.23314994 |
| 53 | white fat cell differentiation (GO:0050872) | 3.21630225 |
| 54 | cullin deneddylation (GO:0010388) | 3.20887244 |
| 55 | regulation of tight junction assembly (GO:2000810) | 3.18636924 |
| 56 | regulation of endothelial cell differentiation (GO:0045601) | 3.16023991 |
| 57 | positive regulation of mitochondrial calcium ion concentration (GO:0051561) | 3.09217962 |
| 58 | homocysteine metabolic process (GO:0050667) | 3.08142894 |
| 59 | response to activity (GO:0014823) | 3.07474716 |
| 60 | membrane assembly (GO:0071709) | 3.04189931 |
| 61 | monocyte differentiation (GO:0030224) | 3.03298819 |
| 62 | regulation of gonadotropin secretion (GO:0032276) | 3.01900164 |
| 63 | cartilage morphogenesis (GO:0060536) | 3.00720220 |
| 64 | response to inactivity (GO:0014854) | 2.99950979 |
| 65 | response to stimulus involved in regulation of muscle adaptation (GO:0014874) | 2.97512378 |
| 66 | positive regulation of insulin-like growth factor receptor signaling pathway (GO:0043568) | 2.95917437 |
| 67 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 cla | 2.95481585 |
| 68 | forebrain neuron differentiation (GO:0021879) | 2.94170426 |
| 69 | phosphatidylglycerol biosynthetic process (GO:0006655) | 2.92402975 |
| 70 | barbed-end actin filament capping (GO:0051016) | 2.92266727 |
| 71 | synaptic vesicle maturation (GO:0016188) | 2.89197535 |
| 72 | extracellular fibril organization (GO:0043206) | 2.87647763 |
| 73 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 2.87296873 |
| 74 | sulfur amino acid catabolic process (GO:0000098) | 2.86170724 |
| 75 | embryonic skeletal joint morphogenesis (GO:0060272) | 2.85733970 |
| 76 | negative regulation of chondrocyte differentiation (GO:0032331) | 2.82963111 |
| 77 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 2.82313142 |
| 78 | NADH dehydrogenase complex assembly (GO:0010257) | 2.82313142 |
| 79 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 2.82313142 |
| 80 | DNA damage response, signal transduction resulting in transcription (GO:0042772) | 2.81071748 |
| 81 | type B pancreatic cell proliferation (GO:0044342) | 2.80763206 |
| 82 | striated muscle adaptation (GO:0014888) | 2.80441012 |
| 83 | neuroblast proliferation (GO:0007405) | 2.79208724 |
| 84 | neuron fate commitment (GO:0048663) | 2.77751666 |
| 85 | actin filament depolymerization (GO:0030042) | 2.76051707 |
| 86 | mesenchymal cell proliferation (GO:0010463) | 2.75419024 |
| 87 | mesenchymal to epithelial transition involved in metanephros morphogenesis (GO:0003337) | 2.75273938 |
| 88 | regulation of gene expression by genetic imprinting (GO:0006349) | 2.73869885 |
| 89 | protein deneddylation (GO:0000338) | 2.72950642 |
| 90 | mechanosensory behavior (GO:0007638) | 2.71750936 |
| 91 | nucleotide salvage (GO:0043173) | 2.70856965 |
| 92 | dendritic spine morphogenesis (GO:0060997) | 2.69700185 |
| 93 | glandular epithelial cell differentiation (GO:0002067) | 2.69629587 |
| 94 | embryonic cranial skeleton morphogenesis (GO:0048701) | 2.69447548 |
| 95 | response to food (GO:0032094) | 2.69286321 |
| 96 | nucleoside transmembrane transport (GO:1901642) | 2.67334780 |
| 97 | negative regulation of DNA biosynthetic process (GO:2000279) | 2.67186195 |
| 98 | negative regulation of JAK-STAT cascade (GO:0046426) | 2.66816333 |
| 99 | mitotic nuclear envelope reassembly (GO:0007084) | 2.65081313 |
| 100 | nuclear envelope reassembly (GO:0031468) | 2.65081313 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 5.64198202 |
| 2 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 4.49208541 |
| 3 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 4.43171388 |
| 4 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 2.97675293 |
| 5 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.82053873 |
| 6 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.63597834 |
| 7 | KLF2_18264089_ChIP-ChIP_MESCs_Mouse | 2.61591828 |
| 8 | KLF5_18264089_ChIP-ChIP_MESCs_Mouse | 2.61591828 |
| 9 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 2.61591828 |
| 10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.58976754 |
| 11 | MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse | 2.53058057 |
| 12 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.51665379 |
| 13 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.47079755 |
| 14 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 2.45848884 |
| 15 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.38060049 |
| 16 | DACH1_20351289_ChIP-Seq_MDA-MB-231_Human | 2.32365974 |
| 17 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.26489448 |
| 18 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 2.22791925 |
| 19 | CCND1_20090754_ChIP-ChIP_RETINA_Mouse | 2.13080419 |
| 20 | CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human | 2.01729007 |
| 21 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.91955382 |
| 22 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.86502446 |
| 23 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.80953740 |
| 24 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.80913260 |
| 25 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.80913260 |
| 26 | EZH2_22144423_ChIP-Seq_EOC_Human | 1.77882231 |
| 27 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.77737392 |
| 28 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 1.77067285 |
| 29 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.70404721 |
| 30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.64055525 |
| 31 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.63210527 |
| 32 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.62499081 |
| 33 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.61830085 |
| 34 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.61061514 |
| 35 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.59801614 |
| 36 | CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat | 1.59712456 |
| 37 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.59527660 |
| 38 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.56704790 |
| 39 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.54589067 |
| 40 | DNAJC2_21179169_ChIP-ChIP_NT2_Human | 1.49989610 |
| 41 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.49680027 |
| 42 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.47324708 |
| 43 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.45440548 |
| 44 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.45028103 |
| 45 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.44367866 |
| 46 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.43399362 |
| 47 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.40846427 |
| 48 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.39447834 |
| 49 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.38643584 |
| 50 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.38442984 |
| 51 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.36958537 |
| 52 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.36500171 |
| 53 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.35688915 |
| 54 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.35103210 |
| 55 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.30304474 |
| 56 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 1.28650115 |
| 57 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 1.28492662 |
| 58 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.27373461 |
| 59 | P68_20966046_ChIP-Seq_HELA_Human | 1.24846888 |
| 60 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.24211607 |
| 61 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.22676171 |
| 62 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.20962704 |
| 63 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.16077469 |
| 64 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.13854002 |
| 65 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 1.10612423 |
| 66 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.07861869 |
| 67 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.05423446 |
| 68 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.05146723 |
| 69 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.03182009 |
| 70 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.02220618 |
| 71 | OLIG2_26023283_ChIP-Seq_AINV15_Mouse | 1.01493333 |
| 72 | SRY_22984422_ChIP-ChIP_TESTIS_Rat | 1.00379629 |
| 73 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 0.99571427 |
| 74 | BCOR_27268052_Chip-Seq_Bcells_Human | 0.99308897 |
| 75 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.97767603 |
| 76 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 0.97192658 |
| 77 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 0.96266540 |
| 78 | CIITA_25753668_ChIP-Seq_RAJI_Human | 0.96063180 |
| 79 | SOX17_20123909_ChIP-Seq_XEN_Mouse | 0.95626265 |
| 80 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 0.94021203 |
| 81 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.93847075 |
| 82 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.93646061 |
| 83 | CBP_21632823_ChIP-Seq_H3396_Human | 0.93273475 |
| 84 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.93210185 |
| 85 | EOMES_21245162_ChIP-Seq_HESCs_Human | 0.93126707 |
| 86 | TP53_22127205_ChIP-Seq_IMR90_Human | 0.92782452 |
| 87 | FOXP1_21924763_ChIP-Seq_HESCs_Human | 0.92651144 |
| 88 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.91891519 |
| 89 | CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse | 0.91743044 |
| 90 | CTCF_27219007_Chip-Seq_Bcells_Human | 0.91138183 |
| 91 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 0.90638527 |
| 92 | CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse | 0.90313752 |
| 93 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 0.89729151 |
| 94 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 0.89302160 |
| 95 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.88723201 |
| 96 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 0.88461922 |
| 97 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 0.86280206 |
| 98 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 0.86095734 |
| 99 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 0.85657247 |
| 100 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.85368893 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0002822_catalepsy | 5.43251877 |
| 2 | MP0003705_abnormal_hypodermis_morpholog | 4.40234480 |
| 3 | MP0005670_abnormal_white_adipose | 3.77623997 |
| 4 | MP0000747_muscle_weakness | 3.45285500 |
| 5 | MP0008789_abnormal_olfactory_epithelium | 2.86795335 |
| 6 | MP0000751_myopathy | 2.78278699 |
| 7 | MP0000749_muscle_degeneration | 2.77982467 |
| 8 | MP0004270_analgesia | 2.46718306 |
| 9 | MP0002095_abnormal_skin_pigmentation | 2.39829040 |
| 10 | MP0000013_abnormal_adipose_tissue | 2.32599281 |
| 11 | MP0005646_abnormal_pituitary_gland | 2.31709570 |
| 12 | MP0000759_abnormal_skeletal_muscle | 2.26886939 |
| 13 | MP0005083_abnormal_biliary_tract | 2.24860310 |
| 14 | MP0002089_abnormal_postnatal_growth/wei | 2.22849016 |
| 15 | MP0010030_abnormal_orbit_morphology | 2.15984394 |
| 16 | MP0000750_abnormal_muscle_regeneration | 2.09438237 |
| 17 | MP0006072_abnormal_retinal_apoptosis | 2.05587641 |
| 18 | MP0004145_abnormal_muscle_electrophysio | 2.05033089 |
| 19 | MP0003123_paternal_imprinting | 1.95639944 |
| 20 | MP0001968_abnormal_touch/_nociception | 1.91666028 |
| 21 | MP0005394_taste/olfaction_phenotype | 1.85571923 |
| 22 | MP0005499_abnormal_olfactory_system | 1.85571923 |
| 23 | MP0002736_abnormal_nociception_after | 1.83019855 |
| 24 | MP0005423_abnormal_somatic_nervous | 1.79165507 |
| 25 | MP0001502_abnormal_circadian_rhythm | 1.65712282 |
| 26 | MP0005257_abnormal_intraocular_pressure | 1.65158823 |
| 27 | MP0002269_muscular_atrophy | 1.64692379 |
| 28 | MP0004885_abnormal_endolymph | 1.64260928 |
| 29 | MP0000534_abnormal_ureter_morphology | 1.62792847 |
| 30 | MP0009780_abnormal_chondrocyte_physiolo | 1.60300941 |
| 31 | MP0000566_synostosis | 1.57118540 |
| 32 | MP0000049_abnormal_middle_ear | 1.54433250 |
| 33 | MP0002735_abnormal_chemical_nociception | 1.53304270 |
| 34 | MP0002734_abnormal_mechanical_nocicepti | 1.51660351 |
| 35 | MP0000003_abnormal_adipose_tissue | 1.50218932 |
| 36 | MP0009745_abnormal_behavioral_response | 1.46911218 |
| 37 | MP0004036_abnormal_muscle_relaxation | 1.46786905 |
| 38 | MP0001905_abnormal_dopamine_level | 1.41492964 |
| 39 | MP0003942_abnormal_urinary_system | 1.40385117 |
| 40 | MP0000516_abnormal_urinary_system | 1.38904738 |
| 41 | MP0005367_renal/urinary_system_phenotyp | 1.38904738 |
| 42 | MP0004087_abnormal_muscle_fiber | 1.37381985 |
| 43 | MP0004147_increased_porphyrin_level | 1.36710989 |
| 44 | MP0002332_abnormal_exercise_endurance | 1.35909052 |
| 45 | MP0002106_abnormal_muscle_physiology | 1.33785070 |
| 46 | MP0008775_abnormal_heart_ventricle | 1.30263553 |
| 47 | MP0003191_abnormal_cellular_cholesterol | 1.20439741 |
| 48 | MP0000537_abnormal_urethra_morphology | 1.19999154 |
| 49 | MP0002733_abnormal_thermal_nociception | 1.19916862 |
| 50 | MP0001529_abnormal_vocalization | 1.18716350 |
| 51 | MP0005360_urolithiasis | 1.16823377 |
| 52 | MP0003786_premature_aging | 1.15590821 |
| 53 | MP0000631_abnormal_neuroendocrine_gland | 1.12430796 |
| 54 | MP0003635_abnormal_synaptic_transmissio | 1.11263743 |
| 55 | MP0005620_abnormal_muscle_contractility | 1.10300202 |
| 56 | MP0006276_abnormal_autonomic_nervous | 1.09197108 |
| 57 | MP0005369_muscle_phenotype | 1.07005402 |
| 58 | MP0002108_abnormal_muscle_morphology | 1.05342352 |
| 59 | MP0008995_early_reproductive_senescence | 1.04848045 |
| 60 | MP0001440_abnormal_grooming_behavior | 1.04832797 |
| 61 | MP0000733_abnormal_muscle_development | 1.03378979 |
| 62 | MP0000778_abnormal_nervous_system | 1.03236376 |
| 63 | MP0002896_abnormal_bone_mineralization | 1.00733328 |
| 64 | MP0004811_abnormal_neuron_physiology | 0.99112047 |
| 65 | MP0002184_abnormal_innervation | 0.98859473 |
| 66 | MP0003959_abnormal_lean_body | 0.96140000 |
| 67 | MP0002064_seizures | 0.92629747 |
| 68 | MP0002069_abnormal_eating/drinking_beha | 0.90638348 |
| 69 | MP0001299_abnormal_eye_distance/ | 0.88765869 |
| 70 | MP0009250_abnormal_appendicular_skeleto | 0.88428244 |
| 71 | MP0001340_abnormal_eyelid_morphology | 0.86660700 |
| 72 | MP0002572_abnormal_emotion/affect_behav | 0.83726319 |
| 73 | MP0001542_abnormal_bone_strength | 0.83633439 |
| 74 | MP0002063_abnormal_learning/memory/cond | 0.83432168 |
| 75 | MP0004142_abnormal_muscle_tone | 0.81164111 |
| 76 | MP0002138_abnormal_hepatobiliary_system | 0.81099408 |
| 77 | MP0001970_abnormal_pain_threshold | 0.80948076 |
| 78 | MP0000955_abnormal_spinal_cord | 0.80882338 |
| 79 | MP0004924_abnormal_behavior | 0.79764759 |
| 80 | MP0005386_behavior/neurological_phenoty | 0.79764759 |
| 81 | MP0002177_abnormal_outer_ear | 0.79477039 |
| 82 | MP0003045_fibrosis | 0.79127627 |
| 83 | MP0004133_heterotaxia | 0.75950677 |
| 84 | MP0004510_myositis | 0.74479124 |
| 85 | MP0002066_abnormal_motor_capabilities/c | 0.73920243 |
| 86 | MP0000163_abnormal_cartilage_morphology | 0.73274744 |
| 87 | MP0000647_abnormal_sebaceous_gland | 0.73158854 |
| 88 | MP0003806_abnormal_nucleotide_metabolis | 0.72620684 |
| 89 | MP0001243_abnormal_dermal_layer | 0.72084905 |
| 90 | MP0001486_abnormal_startle_reflex | 0.71203931 |
| 91 | MP0003755_abnormal_palate_morphology | 0.70960313 |
| 92 | MP0002282_abnormal_trachea_morphology | 0.70826060 |
| 93 | MP0009046_muscle_twitch | 0.69800555 |
| 94 | MP0005375_adipose_tissue_phenotype | 0.69671782 |
| 95 | MP0003638_abnormal_response/metabolism_ | 0.66826926 |
| 96 | MP0002067_abnormal_sensory_capabilities | 0.66653833 |
| 97 | MP0002882_abnormal_neuron_morphology | 0.64307740 |
| 98 | MP0002272_abnormal_nervous_system | 0.63371260 |
| 99 | MP0001270_distended_abdomen | 0.62958585 |
| 100 | MP0005084_abnormal_gallbladder_morpholo | 0.62931103 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Palpebral edema (HP:0100540) | 5.67516724 |
| 2 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 5.24033444 |
| 3 | Abnormality of alanine metabolism (HP:0010916) | 5.24033444 |
| 4 | Hyperalaninemia (HP:0003348) | 5.24033444 |
| 5 | Reduced subcutaneous adipose tissue (HP:0003758) | 5.23824436 |
| 6 | Action tremor (HP:0002345) | 4.73872093 |
| 7 | Mask-like facies (HP:0000298) | 4.26351379 |
| 8 | Exercise-induced myalgia (HP:0003738) | 4.10452167 |
| 9 | Myopathic facies (HP:0002058) | 3.92730249 |
| 10 | Delayed CNS myelination (HP:0002188) | 3.69076640 |
| 11 | Nemaline bodies (HP:0003798) | 3.67312646 |
| 12 | Oligomenorrhea (HP:0000876) | 3.55624215 |
| 13 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 3.12768408 |
| 14 | Congenital sensorineural hearing impairment (HP:0008527) | 3.07726196 |
| 15 | Calcaneovalgus deformity (HP:0001848) | 3.02538440 |
| 16 | Deformed tarsal bones (HP:0008119) | 2.98878473 |
| 17 | Hypoventilation (HP:0002791) | 2.93415917 |
| 18 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.90447336 |
| 19 | Muscle fiber inclusion bodies (HP:0100299) | 2.88926517 |
| 20 | Constricted visual fields (HP:0001133) | 2.87091384 |
| 21 | Distal arthrogryposis (HP:0005684) | 2.80335534 |
| 22 | Stenosis of the external auditory canal (HP:0000402) | 2.77170049 |
| 23 | Down-sloping shoulders (HP:0200021) | 2.71898606 |
| 24 | Hypoalphalipoproteinemia (HP:0003233) | 2.69092687 |
| 25 | Esophageal varix (HP:0002040) | 2.63838598 |
| 26 | Absent phalangeal crease (HP:0006109) | 2.63731414 |
| 27 | Periorbital edema (HP:0100539) | 2.63338083 |
| 28 | Round ear (HP:0100830) | 2.63037727 |
| 29 | Poor speech (HP:0002465) | 2.60419034 |
| 30 | Lower limb amyotrophy (HP:0007210) | 2.59663230 |
| 31 | Microglossia (HP:0000171) | 2.59030877 |
| 32 | Facial edema (HP:0000282) | 2.58279355 |
| 33 | Fatigue (HP:0012378) | 2.57304346 |
| 34 | Abnormality of the fetal cardiovascular system (HP:0010948) | 2.57038454 |
| 35 | Abnormal umbilical cord blood vessels (HP:0011403) | 2.57038454 |
| 36 | Single umbilical artery (HP:0001195) | 2.57038454 |
| 37 | Aplasia involving bones of the extremities (HP:0009825) | 2.56303972 |
| 38 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.56303972 |
| 39 | Aplasia of the phalanges of the hand (HP:0009802) | 2.56303972 |
| 40 | Fibular aplasia (HP:0002990) | 2.46999733 |
| 41 | Myocardial infarction (HP:0001658) | 2.44105231 |
| 42 | Glucose intolerance (HP:0000833) | 2.40998612 |
| 43 | Supranuclear gaze palsy (HP:0000605) | 2.36893443 |
| 44 | Maternal diabetes (HP:0009800) | 2.36132975 |
| 45 | Toxemia of pregnancy (HP:0100603) | 2.34995927 |
| 46 | Ulnar deviation of the wrist (HP:0003049) | 2.33697312 |
| 47 | Insulin-resistant diabetes mellitus (HP:0000831) | 2.33485875 |
| 48 | Increased purine levels (HP:0004368) | 2.30600370 |
| 49 | Hyperuricemia (HP:0002149) | 2.30600370 |
| 50 | Absent speech (HP:0001344) | 2.29082048 |
| 51 | Heterochromia iridis (HP:0001100) | 2.27863613 |
| 52 | Shallow orbits (HP:0000586) | 2.27591739 |
| 53 | Hyperkalemia (HP:0002153) | 2.23156245 |
| 54 | Difficulty climbing stairs (HP:0003551) | 2.22701401 |
| 55 | Abnormality of the columella (HP:0009929) | 2.22071057 |
| 56 | Neoplasm of the heart (HP:0100544) | 2.20516347 |
| 57 | Ankle clonus (HP:0011448) | 2.19588225 |
| 58 | Bell-shaped thorax (HP:0001591) | 2.19078553 |
| 59 | White forelock (HP:0002211) | 2.17544548 |
| 60 | Abnormal finger flexion creases (HP:0006143) | 2.11009067 |
| 61 | Distal lower limb amyotrophy (HP:0008944) | 2.08862724 |
| 62 | Amyloidosis (HP:0011034) | 2.08715595 |
| 63 | Abnormality of the umbilical cord (HP:0010881) | 2.06276120 |
| 64 | Abnormality of the phalanges of the 2nd finger (HP:0009541) | 2.05964141 |
| 65 | Abnormality of the sella turcica (HP:0002679) | 2.04601632 |
| 66 | Conjugated hyperbilirubinemia (HP:0002908) | 2.02122753 |
| 67 | Abnormality of the middle phalanges of the toes (HP:0010183) | 2.00866684 |
| 68 | Broad metatarsal (HP:0001783) | 1.95829035 |
| 69 | Increased serum pyruvate (HP:0003542) | 1.95610681 |
| 70 | Increased connective tissue (HP:0009025) | 1.95571330 |
| 71 | Adrenal hypoplasia (HP:0000835) | 1.94755172 |
| 72 | Insulin resistance (HP:0000855) | 1.94237715 |
| 73 | Synostosis involving the elbow (HP:0003938) | 1.93689349 |
| 74 | Humeroradial synostosis (HP:0003041) | 1.93689349 |
| 75 | Patchy hypopigmentation of hair (HP:0011365) | 1.93552344 |
| 76 | Obstructive sleep apnea (HP:0002870) | 1.92736913 |
| 77 | Hepatocellular necrosis (HP:0001404) | 1.91965203 |
| 78 | Decreased subcutaneous fat (HP:0001002) | 1.91937930 |
| 79 | Bifid uvula (HP:0000193) | 1.91353879 |
| 80 | Acanthosis nigricans (HP:0000956) | 1.90882600 |
| 81 | Progressive cerebellar ataxia (HP:0002073) | 1.88794927 |
| 82 | Clonus (HP:0002169) | 1.88303462 |
| 83 | Exercise-induced muscle cramps (HP:0003710) | 1.83890522 |
| 84 | Multiple lipomas (HP:0001012) | 1.83476271 |
| 85 | Muscle stiffness (HP:0003552) | 1.83299186 |
| 86 | Postural tremor (HP:0002174) | 1.83069402 |
| 87 | Myotonia (HP:0002486) | 1.82330090 |
| 88 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.81949257 |
| 89 | Anxiety (HP:0000739) | 1.80733673 |
| 90 | Cholecystitis (HP:0001082) | 1.76192201 |
| 91 | Abnormal gallbladder physiology (HP:0012438) | 1.76192201 |
| 92 | Ileus (HP:0002595) | 1.72222886 |
| 93 | Myoglobinuria (HP:0002913) | 1.72029654 |
| 94 | Abnormality of glycolysis (HP:0004366) | 1.71979473 |
| 95 | Hyperphosphatemia (HP:0002905) | 1.70861175 |
| 96 | Abnormality of the parietal bone (HP:0002696) | 1.70853686 |
| 97 | Epileptic encephalopathy (HP:0200134) | 1.70783737 |
| 98 | 2-3 toe syndactyly (HP:0004691) | 1.69168771 |
| 99 | Nonprogressive disorder (HP:0003680) | 1.65654422 |
| 100 | Myokymia (HP:0002411) | 1.65464508 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TESK2 | 5.59051807 |
| 2 | TESK1 | 4.58349638 |
| 3 | PHKG2 | 4.20694061 |
| 4 | PHKG1 | 4.20694061 |
| 5 | LIMK1 | 3.88413194 |
| 6 | NME2 | 3.33145803 |
| 7 | LMTK2 | 3.17904097 |
| 8 | VRK2 | 3.09761775 |
| 9 | MOS | 2.13113319 |
| 10 | EPHB2 | 1.83046803 |
| 11 | PAK6 | 1.74769647 |
| 12 | SGK223 | 1.63938149 |
| 13 | SGK494 | 1.63938149 |
| 14 | MAP3K12 | 1.63507731 |
| 15 | CCNB1 | 1.55998129 |
| 16 | MARK1 | 1.54380684 |
| 17 | CSNK1G2 | 1.53359387 |
| 18 | CDK9 | 1.43923585 |
| 19 | AURKA | 1.42568605 |
| 20 | MAP3K3 | 1.39476327 |
| 21 | CASK | 1.37725927 |
| 22 | MAP2K7 | 1.35576047 |
| 23 | CSNK1G3 | 1.30307062 |
| 24 | DAPK1 | 1.28473873 |
| 25 | CSNK1A1L | 1.27794320 |
| 26 | PRKD3 | 1.27123143 |
| 27 | NTRK2 | 1.27110425 |
| 28 | ARAF | 1.23822400 |
| 29 | FGFR2 | 1.22448447 |
| 30 | TAF1 | 1.22070493 |
| 31 | EPHA2 | 1.21068057 |
| 32 | BCKDK | 1.20718303 |
| 33 | MAP2K3 | 1.15435100 |
| 34 | PIM2 | 1.11463379 |
| 35 | DYRK2 | 1.11079355 |
| 36 | OBSCN | 1.09985457 |
| 37 | SGK2 | 1.04839837 |
| 38 | CSNK1G1 | 1.03258413 |
| 39 | ABL2 | 1.01469415 |
| 40 | MAP4K2 | 0.97893482 |
| 41 | NTRK3 | 0.97886224 |
| 42 | SGK3 | 0.96581808 |
| 43 | SCYL2 | 0.94837099 |
| 44 | ICK | 0.92814450 |
| 45 | HIPK2 | 0.89578351 |
| 46 | TIE1 | 0.81935902 |
| 47 | JAK3 | 0.81406100 |
| 48 | MAPKAPK3 | 0.81091320 |
| 49 | GRK7 | 0.80908128 |
| 50 | CAMKK2 | 0.77004878 |
| 51 | PAK4 | 0.76188814 |
| 52 | MINK1 | 0.75845356 |
| 53 | DAPK2 | 0.72010629 |
| 54 | CAMK2G | 0.71048898 |
| 55 | INSRR | 0.69719084 |
| 56 | ADRBK1 | 0.69011317 |
| 57 | MAP3K11 | 0.68673935 |
| 58 | MAPK13 | 0.63485241 |
| 59 | WNK1 | 0.62725379 |
| 60 | SRPK1 | 0.59750419 |
| 61 | RPS6KA2 | 0.55209446 |
| 62 | DYRK1B | 0.55098416 |
| 63 | CAMK1D | 0.54502670 |
| 64 | MST4 | 0.51788085 |
| 65 | NEK9 | 0.51546116 |
| 66 | PDK2 | 0.49053924 |
| 67 | MARK2 | 0.48230189 |
| 68 | CSNK1A1 | 0.47797914 |
| 69 | CDK5 | 0.47234666 |
| 70 | PRKCI | 0.47172242 |
| 71 | STK16 | 0.46903946 |
| 72 | VRK1 | 0.45049949 |
| 73 | PAK1 | 0.45049311 |
| 74 | TYRO3 | 0.44832909 |
| 75 | CAMK2D | 0.44083158 |
| 76 | CAMK1G | 0.41952635 |
| 77 | CHEK2 | 0.41412701 |
| 78 | STK38 | 0.40599165 |
| 79 | CDK14 | 0.38713752 |
| 80 | CDK15 | 0.38313216 |
| 81 | GRK5 | 0.37636129 |
| 82 | CDK11A | 0.37117654 |
| 83 | CDK18 | 0.36766302 |
| 84 | PRKCE | 0.35442398 |
| 85 | FGR | 0.33953103 |
| 86 | MUSK | 0.33328401 |
| 87 | CAMKK1 | 0.32866968 |
| 88 | NTRK1 | 0.31328038 |
| 89 | BRSK1 | 0.31248847 |
| 90 | FER | 0.30108658 |
| 91 | CDK19 | 0.28134877 |
| 92 | ERN1 | 0.27837210 |
| 93 | PTK2 | 0.26825411 |
| 94 | PRKD1 | 0.26062036 |
| 95 | ILK | 0.25447182 |
| 96 | CAMK1 | 0.25244577 |
| 97 | RPS6KA5 | 0.24987934 |
| 98 | KDR | 0.23526313 |
| 99 | ERBB2 | 0.21996790 |
| 100 | GSK3A | 0.21353103 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 3.27520295 |
| 2 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 3.04478811 |
| 3 | Proteasome_Homo sapiens_hsa03050 | 3.02035268 |
| 4 | Galactose metabolism_Homo sapiens_hsa00052 | 2.44853872 |
| 5 | Salivary secretion_Homo sapiens_hsa04970 | 2.41217633 |
| 6 | Sulfur relay system_Homo sapiens_hsa04122 | 2.36974386 |
| 7 | Morphine addiction_Homo sapiens_hsa05032 | 2.35314475 |
| 8 | Tight junction_Homo sapiens_hsa04530 | 2.25380737 |
| 9 | GABAergic synapse_Homo sapiens_hsa04727 | 2.19005661 |
| 10 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.16714431 |
| 11 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 2.16561852 |
| 12 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.12427641 |
| 13 | Regulation of autophagy_Homo sapiens_hsa04140 | 2.03235048 |
| 14 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.99757236 |
| 15 | Nicotine addiction_Homo sapiens_hsa05033 | 1.99439364 |
| 16 | Arginine biosynthesis_Homo sapiens_hsa00220 | 1.96810848 |
| 17 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.90999098 |
| 18 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 1.74425008 |
| 19 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 1.69704381 |
| 20 | Alzheimers disease_Homo sapiens_hsa05010 | 1.69198809 |
| 21 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.67942425 |
| 22 | Circadian entrainment_Homo sapiens_hsa04713 | 1.66495606 |
| 23 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.66029430 |
| 24 | Parkinsons disease_Homo sapiens_hsa05012 | 1.54191947 |
| 25 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.48695463 |
| 26 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.46648748 |
| 27 | Glutathione metabolism_Homo sapiens_hsa00480 | 1.40984658 |
| 28 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.38708868 |
| 29 | Huntingtons disease_Homo sapiens_hsa05016 | 1.35311023 |
| 30 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.29818881 |
| 31 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.26633142 |
| 32 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.23471165 |
| 33 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 1.22542398 |
| 34 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.22292477 |
| 35 | Cholinergic synapse_Homo sapiens_hsa04725 | 1.11176511 |
| 36 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 1.11137981 |
| 37 | Alcoholism_Homo sapiens_hsa05034 | 1.08799662 |
| 38 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.08443338 |
| 39 | Adherens junction_Homo sapiens_hsa04520 | 1.07335908 |
| 40 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.06534222 |
| 41 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.01808183 |
| 42 | Circadian rhythm_Homo sapiens_hsa04710 | 1.01361713 |
| 43 | Carbon metabolism_Homo sapiens_hsa01200 | 0.95466734 |
| 44 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.92800794 |
| 45 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.92653171 |
| 46 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.92588581 |
| 47 | Cocaine addiction_Homo sapiens_hsa05030 | 0.91550642 |
| 48 | Spliceosome_Homo sapiens_hsa03040 | 0.91197906 |
| 49 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.90105242 |
| 50 | Renin secretion_Homo sapiens_hsa04924 | 0.86883405 |
| 51 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.83146526 |
| 52 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.83114363 |
| 53 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.82380380 |
| 54 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.80620543 |
| 55 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.80010630 |
| 56 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.78954573 |
| 57 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.78034626 |
| 58 | Axon guidance_Homo sapiens_hsa04360 | 0.76886437 |
| 59 | Endocytosis_Homo sapiens_hsa04144 | 0.76799754 |
| 60 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.76410565 |
| 61 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.76367452 |
| 62 | Insulin secretion_Homo sapiens_hsa04911 | 0.75965560 |
| 63 | Ribosome_Homo sapiens_hsa03010 | 0.74506520 |
| 64 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.74376744 |
| 65 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.73631212 |
| 66 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 0.72051028 |
| 67 | Oocyte meiosis_Homo sapiens_hsa04114 | 0.71312502 |
| 68 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.70990621 |
| 69 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.70502942 |
| 70 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.70448911 |
| 71 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.70329194 |
| 72 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.68194720 |
| 73 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.68074308 |
| 74 | Hippo signaling pathway_Homo sapiens_hsa04390 | 0.67201313 |
| 75 | Long-term depression_Homo sapiens_hsa04730 | 0.66600077 |
| 76 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.63615166 |
| 77 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.62747735 |
| 78 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.61691500 |
| 79 | RNA polymerase_Homo sapiens_hsa03020 | 0.55399671 |
| 80 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.55147127 |
| 81 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.51973836 |
| 82 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.51686782 |
| 83 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.49563950 |
| 84 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.49322973 |
| 85 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.47406564 |
| 86 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.47058324 |
| 87 | Gap junction_Homo sapiens_hsa04540 | 0.46808205 |
| 88 | Long-term potentiation_Homo sapiens_hsa04720 | 0.46536259 |
| 89 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 0.45208859 |
| 90 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.44809956 |
| 91 | Taste transduction_Homo sapiens_hsa04742 | 0.44540295 |
| 92 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.43976244 |
| 93 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.41954127 |
| 94 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.41942150 |
| 95 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.39962901 |
| 96 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.39129842 |
| 97 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.38305507 |
| 98 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.38183998 |
| 99 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.37493317 |
| 100 | Viral myocarditis_Homo sapiens_hsa05416 | 0.32929260 |

