Rank | Gene Set | Z-score |
---|---|---|
1 | ATP synthesis coupled proton transport (GO:0015986) | 9.70502715 |
2 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 9.70502715 |
3 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 8.93719489 |
4 | respiratory electron transport chain (GO:0022904) | 7.90844235 |
5 | electron transport chain (GO:0022900) | 7.71452358 |
6 | chaperone-mediated protein transport (GO:0072321) | 5.69515958 |
7 | ATP biosynthetic process (GO:0006754) | 5.10613371 |
8 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.06352863 |
9 | ribosomal small subunit assembly (GO:0000028) | 4.94725587 |
10 | * hydrogen ion transmembrane transport (GO:1902600) | 4.88076700 |
11 | protein neddylation (GO:0045116) | 4.84451858 |
12 | purine ribonucleoside triphosphate biosynthetic process (GO:0009206) | 4.83080636 |
13 | purine nucleoside triphosphate biosynthetic process (GO:0009145) | 4.72601963 |
14 | sequestering of actin monomers (GO:0042989) | 4.69105259 |
15 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 4.52749725 |
16 | NADH dehydrogenase complex assembly (GO:0010257) | 4.52749725 |
17 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 4.52749725 |
18 | protein complex biogenesis (GO:0070271) | 4.47417639 |
19 | * proton transport (GO:0015992) | 4.28329501 |
20 | inner mitochondrial membrane organization (GO:0007007) | 4.21899167 |
21 | * hydrogen transport (GO:0006818) | 4.20312685 |
22 | proteasome assembly (GO:0043248) | 4.19505495 |
23 | ribonucleoside triphosphate biosynthetic process (GO:0009201) | 4.14891223 |
24 | neuron cell-cell adhesion (GO:0007158) | 4.01641974 |
25 | mitochondrial respiratory chain complex assembly (GO:0033108) | 4.00455821 |
26 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 3.91644199 |
27 | translational initiation (GO:0006413) | 3.88451417 |
28 | GTP biosynthetic process (GO:0006183) | 3.86716067 |
29 | cytochrome complex assembly (GO:0017004) | 3.85420636 |
30 | axon ensheathment in central nervous system (GO:0032291) | 3.78588845 |
31 | central nervous system myelination (GO:0022010) | 3.78588845 |
32 | ribosomal large subunit biogenesis (GO:0042273) | 3.77980550 |
33 | maturation of SSU-rRNA (GO:0030490) | 3.77403376 |
34 | translation (GO:0006412) | 3.73904249 |
35 | regulation of oxidative phosphorylation (GO:0002082) | 3.70085675 |
36 | ribosomal small subunit biogenesis (GO:0042274) | 3.69260687 |
37 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.66265768 |
38 | termination of RNA polymerase III transcription (GO:0006386) | 3.66265768 |
39 | ATP hydrolysis coupled proton transport (GO:0015991) | 3.58339596 |
40 | energy coupled proton transmembrane transport, against electrochemical gradient (GO:0015988) | 3.58339596 |
41 | protein complex disassembly (GO:0043241) | 3.53626376 |
42 | oxidative phosphorylation (GO:0006119) | 3.52773125 |
43 | viral transcription (GO:0019083) | 3.50499804 |
44 | nucleoside triphosphate biosynthetic process (GO:0009142) | 3.49590558 |
45 | behavioral response to nicotine (GO:0035095) | 3.48089750 |
46 | substantia nigra development (GO:0021762) | 3.45511612 |
47 | macromolecular complex disassembly (GO:0032984) | 3.44647211 |
48 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.38747019 |
49 | protein-cofactor linkage (GO:0018065) | 3.36976543 |
50 | protein targeting to membrane (GO:0006612) | 3.35611752 |
51 | translational termination (GO:0006415) | 3.33480411 |
52 | regulation of dopamine metabolic process (GO:0042053) | 3.32115584 |
53 | regulation of catecholamine metabolic process (GO:0042069) | 3.32115584 |
54 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.31430397 |
55 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.30192479 |
56 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.16737288 |
57 | dopamine transport (GO:0015872) | 3.16644724 |
58 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 3.16508900 |
59 | fatty acid elongation (GO:0030497) | 3.14469104 |
60 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.14028149 |
61 | dopamine biosynthetic process (GO:0042416) | 3.13235536 |
62 | cotranslational protein targeting to membrane (GO:0006613) | 3.12566786 |
63 | UTP biosynthetic process (GO:0006228) | 3.12344415 |
64 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.10488911 |
65 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.10488911 |
66 | presynaptic membrane assembly (GO:0097105) | 3.09817222 |
67 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 3.05664582 |
68 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.04752821 |
69 | mitochondrial transport (GO:0006839) | 3.04063641 |
70 | cellular component biogenesis (GO:0044085) | 3.03538954 |
71 | protein targeting to ER (GO:0045047) | 3.03436197 |
72 | negative regulation of ligase activity (GO:0051352) | 3.03039749 |
73 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.03039749 |
74 | presynaptic membrane organization (GO:0097090) | 3.01972631 |
75 | calcium-mediated signaling using intracellular calcium source (GO:0035584) | 2.99802009 |
76 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.98044344 |
77 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 2.96447697 |
78 | regulation of cellular respiration (GO:0043457) | 2.94294365 |
79 | protein targeting to mitochondrion (GO:0006626) | 2.93770545 |
80 | neuronal action potential propagation (GO:0019227) | 2.93103785 |
81 | establishment of protein localization to mitochondrion (GO:0072655) | 2.92681098 |
82 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.92515711 |
83 | protein localization to endoplasmic reticulum (GO:0070972) | 2.92469291 |
84 | negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315) | 2.92151616 |
85 | cullin deneddylation (GO:0010388) | 2.91094064 |
86 | nuclear-transcribed mRNA catabolic process (GO:0000956) | 2.90231235 |
87 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.90117341 |
88 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.90117341 |
89 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.90117341 |
90 | vocalization behavior (GO:0071625) | 2.88125462 |
91 | platelet dense granule organization (GO:0060155) | 2.87338450 |
92 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.87094193 |
93 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.87094193 |
94 | positive regulation of synapse assembly (GO:0051965) | 2.86751672 |
95 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.85413524 |
96 | neuron recognition (GO:0008038) | 2.85286982 |
97 | generation of precursor metabolites and energy (GO:0006091) | 2.84693200 |
98 | intracellular protein transmembrane import (GO:0044743) | 2.80636320 |
99 | regulation of mitochondrial translation (GO:0070129) | 2.80541840 |
100 | rRNA modification (GO:0000154) | 2.79193675 |
101 | DNA damage response, detection of DNA damage (GO:0042769) | 2.78928846 |
102 | organelle disassembly (GO:1903008) | 2.78885412 |
103 | protein localization to mitochondrion (GO:0070585) | 2.78834446 |
104 | regulation of glutamate secretion (GO:0014048) | 2.78798112 |
105 | cellular protein complex disassembly (GO:0043624) | 2.78540694 |
106 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.75442131 |
107 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.75442131 |
108 | UTP metabolic process (GO:0046051) | 2.75369918 |
109 | signal transduction involved in cell cycle checkpoint (GO:0072395) | 2.74304250 |
110 | positive regulation of ubiquitin-protein transferase activity (GO:0051443) | 2.73143456 |
111 | mRNA catabolic process (GO:0006402) | 2.71736430 |
112 | viral life cycle (GO:0019058) | 2.70353925 |
113 | gamma-aminobutyric acid signaling pathway (GO:0007214) | 2.70059135 |
114 | regulation of protein kinase A signaling (GO:0010738) | 2.68736637 |
115 | spliceosomal snRNP assembly (GO:0000387) | 2.66572678 |
116 | protein localization to synapse (GO:0035418) | 2.65641188 |
117 | protein deneddylation (GO:0000338) | 2.64492866 |
118 | spliceosomal complex assembly (GO:0000245) | 2.64093805 |
119 | translational elongation (GO:0006414) | 2.58493863 |
120 | positive regulation of ligase activity (GO:0051351) | 2.57896389 |
121 | pyrimidine deoxyribonucleotide catabolic process (GO:0009223) | 2.57178326 |
122 | nucleoside diphosphate phosphorylation (GO:0006165) | 2.57050970 |
123 | purine ribonucleoside monophosphate biosynthetic process (GO:0009168) | 2.56735428 |
124 | purine nucleoside monophosphate biosynthetic process (GO:0009127) | 2.56735428 |
125 | synaptic vesicle exocytosis (GO:0016079) | 2.56547779 |
126 | guanosine-containing compound biosynthetic process (GO:1901070) | 2.55147983 |
127 | aerobic respiration (GO:0009060) | 2.54624085 |
128 | intracellular protein transmembrane transport (GO:0065002) | 2.53539595 |
129 | neural nucleus development (GO:0048857) | 2.52321516 |
130 | behavioral response to cocaine (GO:0048148) | 2.51771453 |
131 | protein targeting (GO:0006605) | 2.50865373 |
132 | protein transmembrane transport (GO:0071806) | 2.50068160 |
133 | negative regulation of protein localization to cell surface (GO:2000009) | 2.49731854 |
134 | synaptic transmission, dopaminergic (GO:0001963) | 2.47954390 |
135 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.47870239 |
136 | establishment of integrated proviral latency (GO:0075713) | 2.47042253 |
137 | positive regulation of inositol phosphate biosynthetic process (GO:0060732) | 2.45972050 |
138 | positive regulation of response to oxidative stress (GO:1902884) | 2.45153360 |
139 | positive regulation of cellular response to oxidative stress (GO:1900409) | 2.45153360 |
140 | respiratory chain complex IV assembly (GO:0008535) | 2.43866698 |
141 | protein localization to cilium (GO:0061512) | 2.43062178 |
142 | purine nucleoside biosynthetic process (GO:0042451) | 2.41216102 |
143 | purine ribonucleoside biosynthetic process (GO:0046129) | 2.41216102 |
144 | transmission of nerve impulse (GO:0019226) | 2.41039439 |
145 | regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act | 2.39692658 |
146 | CTP metabolic process (GO:0046036) | 2.36033232 |
147 | CTP biosynthetic process (GO:0006241) | 2.36033232 |
148 | positive regulation of protein homodimerization activity (GO:0090073) | 2.35470408 |
149 | neuron remodeling (GO:0016322) | 2.35371135 |
150 | detection of calcium ion (GO:0005513) | 2.35058958 |
151 | glutamate receptor signaling pathway (GO:0007215) | 2.34666795 |
152 | cellular response to epinephrine stimulus (GO:0071872) | 2.34163507 |
153 | establishment of viral latency (GO:0019043) | 2.34057968 |
154 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 10.3044843 |
Rank | Gene Set | Z-score |
---|---|---|
1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.19244025 |
2 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 3.98944202 |
3 | GBX2_23144817_ChIP-Seq_PC3_Human | 3.02877716 |
4 | TAF15_26573619_Chip-Seq_HEK293_Human | 2.82475289 |
5 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 2.69137503 |
6 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.67333218 |
7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.59320068 |
8 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 2.57203714 |
9 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.48241282 |
10 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 2.47951890 |
11 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 2.46970924 |
12 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 2.42142826 |
13 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 2.42103717 |
14 | * ELK1_19687146_ChIP-ChIP_HELA_Human | 2.39955685 |
15 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 2.38971504 |
16 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 2.15181814 |
17 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.12755906 |
18 | * VDR_23849224_ChIP-Seq_CD4+_Human | 2.12143553 |
19 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.11253656 |
20 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 2.09777892 |
21 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.09367722 |
22 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 2.08146893 |
23 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 2.05709812 |
24 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 2.00762326 |
25 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 2.00554105 |
26 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.98924369 |
27 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.98466652 |
28 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.98466652 |
29 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 1.93026418 |
30 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.91315824 |
31 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.89714860 |
32 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 1.88842632 |
33 | * ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 1.88738531 |
34 | FUS_26573619_Chip-Seq_HEK293_Human | 1.87503742 |
35 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.80130868 |
36 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.75002163 |
37 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.73870165 |
38 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.73274460 |
39 | FOXP3_21729870_ChIP-Seq_TREG_Human | 1.71650398 |
40 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.69390867 |
41 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.67493105 |
42 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.67059898 |
43 | * TTF2_22483619_ChIP-Seq_HELA_Human | 1.67013515 |
44 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.66809701 |
45 | REST_21632747_ChIP-Seq_MESCs_Mouse | 1.66686499 |
46 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 1.63576801 |
47 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 1.62811022 |
48 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.62469484 |
49 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.60516537 |
50 | P300_19829295_ChIP-Seq_ESCs_Human | 1.58852491 |
51 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.58162567 |
52 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.57445514 |
53 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.55032544 |
54 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.52345298 |
55 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.49725693 |
56 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.48078483 |
57 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.47467539 |
58 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.43520991 |
59 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.43098628 |
60 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.41246159 |
61 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 1.41104786 |
62 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.40264575 |
63 | * E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.40115829 |
64 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 1.39515782 |
65 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.38075676 |
66 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.37466513 |
67 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.36858697 |
68 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.34494864 |
69 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 1.33137283 |
70 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 1.32691805 |
71 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.32146559 |
72 | FOXP2_21765815_ChIP-ChIP_NEURO2A_Mouse | 1.30991852 |
73 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 1.30598020 |
74 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.29412356 |
75 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.28633221 |
76 | * ELK1_22589737_ChIP-Seq_MCF10A_Human | 1.27781645 |
77 | * JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 1.26633872 |
78 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.25213457 |
79 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 1.25186703 |
80 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.24164362 |
81 | * PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.23538274 |
82 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.22968783 |
83 | * ETS1_20019798_ChIP-Seq_JURKAT_Human | 1.20682466 |
84 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.20530125 |
85 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.20081255 |
86 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.17041404 |
87 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.13297117 |
88 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 1.13157624 |
89 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.13034317 |
90 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.12658558 |
91 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.11642939 |
92 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.10881901 |
93 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.09939278 |
94 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.09753068 |
95 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 1.09200562 |
96 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.09073470 |
97 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.08199592 |
98 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 1.07810900 |
99 | AR_21572438_ChIP-Seq_LNCaP_Human | 1.04784672 |
100 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.04439106 |
101 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.04116400 |
102 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 1.04108847 |
103 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.04034571 |
104 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.02204222 |
105 | * ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 1.01349615 |
106 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.01138643 |
107 | EWS_26573619_Chip-Seq_HEK293_Human | 1.00860979 |
108 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 1.00836086 |
109 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 0.99688578 |
110 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.99629764 |
111 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 0.98310380 |
112 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.97549292 |
113 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.97549292 |
114 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96437276 |
115 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.96093944 |
116 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 0.96091797 |
117 | NR3C1_23031785_ChIP-Seq_PC12_Mouse | 0.95641933 |
118 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95052415 |
119 | * JUN_21703547_ChIP-Seq_K562_Human | 0.94387659 |
120 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.94386889 |
121 | * HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.94257393 |
122 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 0.92649061 |
123 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 0.92057204 |
124 | CRX_20693478_ChIP-Seq_ADULT_RETINA_Mouse | 0.91913399 |
125 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.91703276 |
126 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.90737780 |
127 | TAL1_26923725_Chip-Seq_HPCs_Mouse | 0.90450901 |
128 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 0.89967219 |
129 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 0.89934784 |
130 | * MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 0.89132484 |
131 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 0.88083180 |
132 | BCAT_22108803_ChIP-Seq_LS180_Human | 0.86435491 |
133 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.86211499 |
134 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.86170806 |
135 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 0.85775352 |
136 | ERG_20517297_ChIP-Seq_VCAP_Human | 0.85449375 |
137 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.84715137 |
138 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.84715137 |
139 | KDM2B_26808549_Chip-Seq_REH_Human | 0.84010176 |
140 | EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse | 0.82836982 |
141 | RARB_27405468_Chip-Seq_BRAIN_Mouse | 0.82595073 |
142 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 0.81914814 |
143 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 0.81346584 |
144 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.80662703 |
145 | NCOR_22424771_ChIP-Seq_293T_Human | 0.80544579 |
146 | AR_20517297_ChIP-Seq_VCAP_Human | 0.80531582 |
147 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 0.79960943 |
148 | PAX6_23342162_ChIP-ChIP_BETA-FORBRAIN-LENS_Mouse | 0.79897334 |
149 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 0.79745924 |
150 | P53_22387025_ChIP-Seq_ESCs_Mouse | 0.79422513 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003880_abnormal_central_pattern | 5.31778620 |
2 | MP0001529_abnormal_vocalization | 3.54166813 |
3 | MP0002837_dystrophic_cardiac_calcinosis | 3.44391538 |
4 | MP0009379_abnormal_foot_pigmentation | 3.40481508 |
5 | MP0006276_abnormal_autonomic_nervous | 3.00899829 |
6 | MP0001905_abnormal_dopamine_level | 2.66267108 |
7 | MP0001968_abnormal_touch/_nociception | 2.48194892 |
8 | MP0009745_abnormal_behavioral_response | 2.46615241 |
9 | MP0003635_abnormal_synaptic_transmissio | 2.39042245 |
10 | MP0002736_abnormal_nociception_after | 2.36550783 |
11 | MP0002064_seizures | 2.35940030 |
12 | MP0004270_analgesia | 2.30122434 |
13 | MP0002938_white_spotting | 2.28075532 |
14 | MP0002272_abnormal_nervous_system | 2.25870153 |
15 | MP0009046_muscle_twitch | 2.22333556 |
16 | MP0001440_abnormal_grooming_behavior | 2.21011291 |
17 | MP0004859_abnormal_synaptic_plasticity | 2.08251176 |
18 | MP0003646_muscle_fatigue | 2.06599959 |
19 | MP0002735_abnormal_chemical_nociception | 2.04568104 |
20 | MP0004142_abnormal_muscle_tone | 2.04474856 |
21 | MP0002572_abnormal_emotion/affect_behav | 2.04381193 |
22 | MP0001486_abnormal_startle_reflex | 1.97855270 |
23 | MP0002734_abnormal_mechanical_nocicepti | 1.96333215 |
24 | MP0005423_abnormal_somatic_nervous | 1.88808512 |
25 | MP0000778_abnormal_nervous_system | 1.88174950 |
26 | MP0003011_delayed_dark_adaptation | 1.85833470 |
27 | MP0002063_abnormal_learning/memory/cond | 1.85394932 |
28 | MP0003186_abnormal_redox_activity | 1.82692389 |
29 | MP0002733_abnormal_thermal_nociception | 1.77532045 |
30 | MP0001970_abnormal_pain_threshold | 1.71883321 |
31 | MP0003136_yellow_coat_color | 1.70897725 |
32 | MP0000751_myopathy | 1.68522199 |
33 | MP0002067_abnormal_sensory_capabilities | 1.67802392 |
34 | MP0004742_abnormal_vestibular_system | 1.62408253 |
35 | MP0001501_abnormal_sleep_pattern | 1.60328335 |
36 | MP0002822_catalepsy | 1.59669249 |
37 | MP0006036_abnormal_mitochondrial_physio | 1.58988475 |
38 | MP0005386_behavior/neurological_phenoty | 1.58135581 |
39 | MP0004924_abnormal_behavior | 1.58135581 |
40 | MP0003329_amyloid_beta_deposits | 1.58053346 |
41 | MP0003806_abnormal_nucleotide_metabolis | 1.57295581 |
42 | MP0001984_abnormal_olfaction | 1.57233205 |
43 | MP0005084_abnormal_gallbladder_morpholo | 1.57221456 |
44 | MP0000566_synostosis | 1.54048713 |
45 | MP0004215_abnormal_myocardial_fiber | 1.52927998 |
46 | MP0003121_genomic_imprinting | 1.52474031 |
47 | MP0004133_heterotaxia | 1.52462182 |
48 | MP0003787_abnormal_imprinting | 1.51287999 |
49 | MP0008877_abnormal_DNA_methylation | 1.50591318 |
50 | MP0005409_darkened_coat_color | 1.47636817 |
51 | MP0008995_early_reproductive_senescence | 1.45285149 |
52 | MP0002184_abnormal_innervation | 1.44662055 |
53 | MP0001188_hyperpigmentation | 1.43490495 |
54 | MP0003718_maternal_effect | 1.43065597 |
55 | MP0004036_abnormal_muscle_relaxation | 1.43056623 |
56 | MP0001485_abnormal_pinna_reflex | 1.39765666 |
57 | MP0002277_abnormal_respiratory_mucosa | 1.37784928 |
58 | MP0008058_abnormal_DNA_repair | 1.34471756 |
59 | MP0003938_abnormal_ear_development | 1.31184049 |
60 | MP0002332_abnormal_exercise_endurance | 1.30638682 |
61 | MP0000920_abnormal_myelination | 1.30637142 |
62 | MP0010030_abnormal_orbit_morphology | 1.27256446 |
63 | MP0006035_abnormal_mitochondrial_morpho | 1.24642870 |
64 | MP0005379_endocrine/exocrine_gland_phen | 1.24618566 |
65 | MP0002557_abnormal_social/conspecific_i | 1.22841859 |
66 | MP0006072_abnormal_retinal_apoptosis | 1.22440017 |
67 | MP0002909_abnormal_adrenal_gland | 1.22196156 |
68 | MP0004145_abnormal_muscle_electrophysio | 1.21840812 |
69 | MP0002163_abnormal_gland_morphology | 1.21297646 |
70 | MP0005551_abnormal_eye_electrophysiolog | 1.20037898 |
71 | MP0002653_abnormal_ependyma_morphology | 1.19571857 |
72 | MP0001727_abnormal_embryo_implantation | 1.17906956 |
73 | MP0008875_abnormal_xenobiotic_pharmacok | 1.17797142 |
74 | MP0002638_abnormal_pupillary_reflex | 1.17462734 |
75 | MP0000569_abnormal_digit_pigmentation | 1.17026875 |
76 | MP0004147_increased_porphyrin_level | 1.16554380 |
77 | MP0002102_abnormal_ear_morphology | 1.15759739 |
78 | MP0003890_abnormal_embryonic-extraembry | 1.15159469 |
79 | MP0002066_abnormal_motor_capabilities/c | 1.13829476 |
80 | MP0003137_abnormal_impulse_conducting | 1.13675300 |
81 | MP0010386_abnormal_urinary_bladder | 1.13156976 |
82 | MP0005646_abnormal_pituitary_gland | 1.12903694 |
83 | MP0001963_abnormal_hearing_physiology | 1.12607115 |
84 | MP0000026_abnormal_inner_ear | 1.11153438 |
85 | MP0001293_anophthalmia | 1.10704732 |
86 | MP0005171_absent_coat_pigmentation | 1.10494538 |
87 | MP0005410_abnormal_fertilization | 1.07087898 |
88 | MP0000749_muscle_degeneration | 1.06453723 |
89 | MP0002882_abnormal_neuron_morphology | 1.06425370 |
90 | MP0004085_abnormal_heartbeat | 1.03479261 |
91 | MP0005535_abnormal_body_temperature | 1.02993261 |
92 | MP0004885_abnormal_endolymph | 1.01565931 |
93 | MP0002752_abnormal_somatic_nervous | 1.01295560 |
94 | MP0002876_abnormal_thyroid_physiology | 0.98859858 |
95 | MP0003123_paternal_imprinting | 0.98485324 |
96 | MP0002229_neurodegeneration | 0.98155315 |
97 | MP0004043_abnormal_pH_regulation | 0.97420930 |
98 | MP0002751_abnormal_autonomic_nervous | 0.95865281 |
99 | MP0003195_calcinosis | 0.95205675 |
100 | MP0000538_abnormal_urinary_bladder | 0.94565300 |
101 | MP0002095_abnormal_skin_pigmentation | 0.94146824 |
102 | MP0004484_altered_response_of | 0.93279163 |
103 | MP0001664_abnormal_digestion | 0.92588900 |
104 | MP0005408_hypopigmentation | 0.92446601 |
105 | MP0000955_abnormal_spinal_cord | 0.92140331 |
106 | MP0002234_abnormal_pharynx_morphology | 0.90731509 |
107 | MP0008872_abnormal_physiological_respon | 0.89920726 |
108 | MP0003122_maternal_imprinting | 0.89746708 |
109 | MP0005195_abnormal_posterior_eye | 0.88836348 |
110 | MP0005330_cardiomyopathy | 0.87547206 |
111 | MP0002090_abnormal_vision | 0.87088088 |
112 | MP0003950_abnormal_plasma_membrane | 0.87013633 |
113 | MP0005332_abnormal_amino_acid | 0.85604655 |
114 | MP0000372_irregular_coat_pigmentation | 0.84860887 |
115 | MP0005620_abnormal_muscle_contractility | 0.84640317 |
116 | MP0002972_abnormal_cardiac_muscle | 0.84255183 |
117 | MP0001502_abnormal_circadian_rhythm | 0.83814765 |
118 | MP0003283_abnormal_digestive_organ | 0.83151803 |
119 | MP0003786_premature_aging | 0.82439979 |
120 | MP0002160_abnormal_reproductive_system | 0.81426926 |
121 | MP0001986_abnormal_taste_sensitivity | 0.80444140 |
122 | MP0001764_abnormal_homeostasis | 0.79434861 |
123 | MP0004381_abnormal_hair_follicle | 0.79007385 |
124 | MP0003634_abnormal_glial_cell | 0.78990278 |
125 | MP0005394_taste/olfaction_phenotype | 0.78950971 |
126 | MP0005499_abnormal_olfactory_system | 0.78950971 |
127 | MP0000631_abnormal_neuroendocrine_gland | 0.78043682 |
128 | MP0008569_lethality_at_weaning | 0.77839691 |
129 | MP0000462_abnormal_digestive_system | 0.77175178 |
130 | MP0008789_abnormal_olfactory_epithelium | 0.76355586 |
131 | MP0005645_abnormal_hypothalamus_physiol | 0.73879673 |
132 | MP0002152_abnormal_brain_morphology | 0.72548291 |
133 | MP0005253_abnormal_eye_physiology | 0.68321855 |
134 | MP0002106_abnormal_muscle_physiology | 0.67702230 |
135 | MP0004811_abnormal_neuron_physiology | 0.65717196 |
136 | MP0000230_abnormal_systemic_arterial | 0.65227745 |
137 | MP0006292_abnormal_olfactory_placode | 0.65213796 |
138 | MP0000013_abnormal_adipose_tissue | 0.64995269 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Acute necrotizing encephalopathy (HP:0006965) | 7.50376056 |
2 | Abnormal mitochondria in muscle tissue (HP:0008316) | 6.71669988 |
3 | Mitochondrial inheritance (HP:0001427) | 6.48599250 |
4 | Progressive macrocephaly (HP:0004481) | 6.44117052 |
5 | Acute encephalopathy (HP:0006846) | 6.15321362 |
6 | Increased CSF lactate (HP:0002490) | 5.31138408 |
7 | Increased hepatocellular lipid droplets (HP:0006565) | 5.24589801 |
8 | Hepatocellular necrosis (HP:0001404) | 4.98889739 |
9 | Lipid accumulation in hepatocytes (HP:0006561) | 4.74144848 |
10 | Renal Fanconi syndrome (HP:0001994) | 4.58504563 |
11 | Optic disc pallor (HP:0000543) | 4.49059158 |
12 | Cerebral edema (HP:0002181) | 4.47418009 |
13 | Hepatic necrosis (HP:0002605) | 4.19711757 |
14 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 4.12965853 |
15 | Increased serum pyruvate (HP:0003542) | 4.11846262 |
16 | Abnormality of glycolysis (HP:0004366) | 4.11846262 |
17 | Increased intramyocellular lipid droplets (HP:0012240) | 3.98521422 |
18 | Leukodystrophy (HP:0002415) | 3.86457118 |
19 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 3.69182744 |
20 | Exercise intolerance (HP:0003546) | 3.68860885 |
21 | Respiratory failure (HP:0002878) | 3.66686283 |
22 | Reticulocytopenia (HP:0001896) | 3.51523889 |
23 | Myokymia (HP:0002411) | 3.49470233 |
24 | Focal motor seizures (HP:0011153) | 3.48161299 |
25 | Increased muscle lipid content (HP:0009058) | 3.42883246 |
26 | Lactic acidosis (HP:0003128) | 3.37810996 |
27 | Congenital nonbullous ichthyosiform erythroderma (HP:0007479) | 3.29506189 |
28 | 3-Methylglutaconic aciduria (HP:0003535) | 3.23909760 |
29 | Exertional dyspnea (HP:0002875) | 3.13249180 |
30 | Congenital, generalized hypertrichosis (HP:0004540) | 3.09510740 |
31 | Parakeratosis (HP:0001036) | 3.07817184 |
32 | Abnormality of renal resorption (HP:0011038) | 3.03141434 |
33 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.94142669 |
34 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.94142669 |
35 | X-linked dominant inheritance (HP:0001423) | 2.89228285 |
36 | Increased serum lactate (HP:0002151) | 2.87172826 |
37 | Molar tooth sign on MRI (HP:0002419) | 2.84308576 |
38 | Abnormality of midbrain morphology (HP:0002418) | 2.84308576 |
39 | Respiratory difficulties (HP:0002880) | 2.75326760 |
40 | Pancreatic cysts (HP:0001737) | 2.69407298 |
41 | Pancreatic fibrosis (HP:0100732) | 2.67634846 |
42 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.66610766 |
43 | Sensory axonal neuropathy (HP:0003390) | 2.65450534 |
44 | Muscle hypertrophy of the lower extremities (HP:0008968) | 2.61904297 |
45 | Hyperphosphaturia (HP:0003109) | 2.60315214 |
46 | Pheochromocytoma (HP:0002666) | 2.56010461 |
47 | Neuroendocrine neoplasm (HP:0100634) | 2.49479093 |
48 | Generalized aminoaciduria (HP:0002909) | 2.49006184 |
49 | Methylmalonic acidemia (HP:0002912) | 2.48057685 |
50 | True hermaphroditism (HP:0010459) | 2.46473173 |
51 | Nephronophthisis (HP:0000090) | 2.42506750 |
52 | Atonic seizures (HP:0010819) | 2.38360004 |
53 | Atrophy/Degeneration involving the corticospinal tracts (HP:0007372) | 2.37692350 |
54 | Degeneration of the lateral corticospinal tracts (HP:0002314) | 2.37692350 |
55 | Abnormality of urine glucose concentration (HP:0011016) | 2.35975943 |
56 | Glycosuria (HP:0003076) | 2.35975943 |
57 | Calf muscle hypertrophy (HP:0008981) | 2.31865687 |
58 | Limb dystonia (HP:0002451) | 2.28496747 |
59 | Pallor (HP:0000980) | 2.26665549 |
60 | Septo-optic dysplasia (HP:0100842) | 2.25793366 |
61 | Methylmalonic aciduria (HP:0012120) | 2.25467183 |
62 | Abnormal urine phosphate concentration (HP:0012599) | 2.20766323 |
63 | Congenital ichthyosiform erythroderma (HP:0007431) | 2.19664048 |
64 | Emotional lability (HP:0000712) | 2.18647692 |
65 | Cerebral hemorrhage (HP:0001342) | 2.18267314 |
66 | CNS demyelination (HP:0007305) | 2.17607720 |
67 | Sclerocornea (HP:0000647) | 2.17604934 |
68 | Hyperventilation (HP:0002883) | 2.15863909 |
69 | Macrocytic anemia (HP:0001972) | 2.11784738 |
70 | Neurofibrillary tangles (HP:0002185) | 2.10990423 |
71 | Absence seizures (HP:0002121) | 2.10305117 |
72 | Lethargy (HP:0001254) | 2.10033398 |
73 | Abnormality of the labia minora (HP:0012880) | 2.08241763 |
74 | Abnormal number of erythroid precursors (HP:0012131) | 2.07778310 |
75 | Abnormal pupillary function (HP:0007686) | 2.04077787 |
76 | Retinal dysplasia (HP:0007973) | 2.03981533 |
77 | Focal seizures (HP:0007359) | 2.03416571 |
78 | Sudden death (HP:0001699) | 2.02242675 |
79 | Cerebral inclusion bodies (HP:0100314) | 2.00591429 |
80 | Dialeptic seizures (HP:0011146) | 2.00564984 |
81 | Medial flaring of the eyebrow (HP:0010747) | 2.00523954 |
82 | Abnormal ciliary motility (HP:0012262) | 2.00433799 |
83 | Poor suck (HP:0002033) | 1.98234213 |
84 | Type I transferrin isoform profile (HP:0003642) | 1.94211133 |
85 | Visual hallucinations (HP:0002367) | 1.90628438 |
86 | Delusions (HP:0000746) | 1.88427917 |
87 | Anxiety (HP:0000739) | 1.88177599 |
88 | Amblyopia (HP:0000646) | 1.87507755 |
89 | Nephrogenic diabetes insipidus (HP:0009806) | 1.86164548 |
90 | Amniotic constriction ring (HP:0009775) | 1.86117906 |
91 | Abnormality of placental membranes (HP:0011409) | 1.86117906 |
92 | Aplastic anemia (HP:0001915) | 1.82193697 |
93 | Progressive external ophthalmoplegia (HP:0000590) | 1.81543843 |
94 | Abnormality of the renal medulla (HP:0100957) | 1.81442626 |
95 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.80204045 |
96 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.80204045 |
97 | Renal tubular dysfunction (HP:0000124) | 1.78890027 |
98 | Hyperglycinemia (HP:0002154) | 1.78780379 |
99 | Congenital stationary night blindness (HP:0007642) | 1.78203314 |
100 | Colon cancer (HP:0003003) | 1.77392177 |
101 | Absent septum pellucidum (HP:0001331) | 1.76323543 |
102 | Epileptic encephalopathy (HP:0200134) | 1.76212502 |
103 | Hypothermia (HP:0002045) | 1.75970249 |
104 | Polyphagia (HP:0002591) | 1.75376748 |
105 | Gait imbalance (HP:0002141) | 1.74222322 |
106 | Abnormality of secondary sexual hair (HP:0009888) | 1.71166323 |
107 | Abnormality of the axillary hair (HP:0100134) | 1.71166323 |
108 | Renal cortical cysts (HP:0000803) | 1.70837462 |
109 | Optic nerve hypoplasia (HP:0000609) | 1.69416470 |
110 | Male pseudohermaphroditism (HP:0000037) | 1.69057023 |
111 | Broad-based gait (HP:0002136) | 1.68489585 |
112 | Generalized tonic-clonic seizures (HP:0002069) | 1.68472668 |
113 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.68441938 |
114 | Absent/shortened dynein arms (HP:0200106) | 1.68441938 |
115 | Blindness (HP:0000618) | 1.67374657 |
116 | Concave nail (HP:0001598) | 1.66760996 |
117 | Oral leukoplakia (HP:0002745) | 1.65861860 |
118 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.65715428 |
119 | Dicarboxylic aciduria (HP:0003215) | 1.65715428 |
120 | Abnormal respiratory motile cilium physiology (HP:0012261) | 1.65423546 |
121 | Hypoplastic left heart (HP:0004383) | 1.64119620 |
122 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.63725069 |
123 | Vaginal atresia (HP:0000148) | 1.62027327 |
124 | Neoplasm of head and neck (HP:0012288) | 1.61192742 |
125 | Esophageal neoplasm (HP:0100751) | 1.61192742 |
126 | Hypoplasia of the pons (HP:0012110) | 1.61019577 |
127 | Anencephaly (HP:0002323) | 1.60924609 |
128 | Abnormality of vitamin B metabolism (HP:0004340) | 1.60423175 |
129 | Genital tract atresia (HP:0001827) | 1.60213684 |
130 | Vomiting (HP:0002013) | 1.60121826 |
131 | Abnormality of the renal cortex (HP:0011035) | 1.59622140 |
132 | Type II lissencephaly (HP:0007260) | 1.59414822 |
133 | Aplasia/Hypoplasia of the sacrum (HP:0008517) | 1.59346792 |
134 | Esotropia (HP:0000565) | 1.59218187 |
135 | Congenital primary aphakia (HP:0007707) | 1.58239582 |
136 | Abnormality of the anterior horn cell (HP:0006802) | 1.57785679 |
137 | Degeneration of anterior horn cells (HP:0002398) | 1.57785679 |
138 | Abnormality of the corticospinal tract (HP:0002492) | 1.57715627 |
139 | Aplasia/hypoplasia of the uterus (HP:0008684) | 1.57593467 |
140 | Abnormal gallbladder physiology (HP:0012438) | 1.56726310 |
141 | Cholecystitis (HP:0001082) | 1.56726310 |
142 | Absent thumb (HP:0009777) | 1.56662704 |
143 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.54816189 |
144 | Hypoglycemic coma (HP:0001325) | 1.54524890 |
145 | Rib fusion (HP:0000902) | 1.54389260 |
146 | Febrile seizures (HP:0002373) | 1.52495452 |
Rank | Gene Set | Z-score |
---|---|---|
1 | VRK2 | 4.16636593 |
2 | MAP3K12 | 3.63940723 |
3 | NME1 | 3.28134859 |
4 | STK39 | 3.09168026 |
5 | PNCK | 2.99304699 |
6 | CASK | 2.77993339 |
7 | ZAK | 2.65436074 |
8 | MYLK | 2.55775476 |
9 | OXSR1 | 2.42003544 |
10 | PBK | 2.11248517 |
11 | EPHA4 | 2.09699631 |
12 | WNK4 | 2.09548711 |
13 | NME2 | 2.03978325 |
14 | GRK5 | 2.01648329 |
15 | GRK7 | 1.87822950 |
16 | MST4 | 1.87811440 |
17 | MAP2K7 | 1.86525221 |
18 | MAP3K4 | 1.86343149 |
19 | ARAF | 1.84007234 |
20 | NTRK3 | 1.79640957 |
21 | STK16 | 1.75281724 |
22 | MARK1 | 1.74619181 |
23 | CDK19 | 1.72495554 |
24 | TNIK | 1.70140656 |
25 | MAP4K2 | 1.68671455 |
26 | TLK1 | 1.64827491 |
27 | CDC7 | 1.62826903 |
28 | BCR | 1.60220396 |
29 | RIPK4 | 1.57317961 |
30 | LIMK1 | 1.50654838 |
31 | FGR | 1.45519074 |
32 | NUAK1 | 1.44981581 |
33 | PINK1 | 1.39533134 |
34 | UHMK1 | 1.38325793 |
35 | GRK1 | 1.37039698 |
36 | MUSK | 1.36955743 |
37 | TAF1 | 1.35402269 |
38 | CAMK2B | 1.32744114 |
39 | PLK2 | 1.26036456 |
40 | MAPK13 | 1.22122597 |
41 | BMPR2 | 1.21499088 |
42 | CAMK2A | 1.20724229 |
43 | OBSCN | 1.19873225 |
44 | NEK1 | 1.19813918 |
45 | CSNK1G3 | 1.17688367 |
46 | MINK1 | 1.16166654 |
47 | PKN1 | 1.14605715 |
48 | PLK3 | 1.14277132 |
49 | MAP2K4 | 1.14103004 |
50 | MAPKAPK5 | 1.13418128 |
51 | CAMK2D | 1.09912027 |
52 | WNK3 | 1.04733838 |
53 | BMPR1B | 1.02622024 |
54 | DAPK3 | 1.01567657 |
55 | NTRK2 | 1.01147545 |
56 | INSRR | 1.00790297 |
57 | TRIM28 | 1.00748734 |
58 | ROCK2 | 0.99696379 |
59 | EPHB2 | 0.97269458 |
60 | PHKG1 | 0.96947439 |
61 | PHKG2 | 0.96947439 |
62 | WEE1 | 0.96361148 |
63 | ADRBK2 | 0.96241194 |
64 | DYRK2 | 0.96098397 |
65 | CSNK1G2 | 0.94179818 |
66 | PTK2B | 0.90861297 |
67 | ADRBK1 | 0.90383342 |
68 | PLK4 | 0.85698497 |
69 | FRK | 0.85133780 |
70 | TESK1 | 0.84928878 |
71 | CAMK2G | 0.82790164 |
72 | MAP3K9 | 0.82216153 |
73 | VRK1 | 0.79812807 |
74 | NTRK1 | 0.77265224 |
75 | PRKCE | 0.77220194 |
76 | DYRK3 | 0.76690866 |
77 | CDK5 | 0.75251799 |
78 | CDK14 | 0.74323117 |
79 | PAK3 | 0.72752790 |
80 | PRKCG | 0.71400881 |
81 | PDK3 | 0.70074220 |
82 | PDK4 | 0.70074220 |
83 | PLK1 | 0.69402637 |
84 | PASK | 0.68915814 |
85 | CSNK1G1 | 0.68449223 |
86 | PIM2 | 0.66666704 |
87 | BRAF | 0.66439168 |
88 | ABL2 | 0.66125687 |
89 | PRKACA | 0.65095650 |
90 | CDK15 | 0.63409265 |
91 | CDK18 | 0.62958226 |
92 | ERBB3 | 0.62027900 |
93 | GRK6 | 0.61983657 |
94 | CSNK1A1L | 0.61846266 |
95 | CSNK2A2 | 0.61618991 |
96 | DAPK1 | 0.61029458 |
97 | BUB1 | 0.60531852 |
98 | CDK11A | 0.59495885 |
99 | FES | 0.58243015 |
100 | EIF2AK3 | 0.57648922 |
101 | DAPK2 | 0.56750911 |
102 | AURKB | 0.56644854 |
103 | CHEK2 | 0.56470513 |
104 | CSNK2A1 | 0.52818751 |
105 | ILK | 0.52169878 |
106 | DYRK1A | 0.51030193 |
107 | CDK8 | 0.49687460 |
108 | TESK2 | 0.49356444 |
109 | RPS6KA5 | 0.48654656 |
110 | LMTK2 | 0.48628048 |
111 | MKNK1 | 0.48557382 |
112 | PRKCI | 0.48103744 |
113 | CSNK1E | 0.45964902 |
114 | MKNK2 | 0.45736114 |
115 | CSNK1A1 | 0.45543580 |
116 | CCNB1 | 0.45538068 |
117 | TTK | 0.45032890 |
118 | PAK6 | 0.44922705 |
119 | IRAK2 | 0.44435089 |
120 | MAP3K11 | 0.43962875 |
121 | PRPF4B | 0.43010160 |
122 | SRPK1 | 0.42221970 |
123 | PDK2 | 0.41877498 |
124 | WNK1 | 0.40871989 |
125 | ROCK1 | 0.39487884 |
126 | MAPK12 | 0.37194451 |
127 | STK11 | 0.36936794 |
128 | MAPK4 | 0.35545238 |
129 | EIF2AK1 | 0.35277375 |
130 | PRKG1 | 0.34202702 |
131 | AURKA | 0.33955737 |
132 | PRKCQ | 0.33933725 |
133 | MAPK15 | 0.33634007 |
134 | PRKCA | 0.32216769 |
135 | BCKDK | 0.32030881 |
136 | SIK2 | 0.30011667 |
137 | PRKACB | 0.29866475 |
Rank | Gene Set | Z-score |
---|---|---|
1 | * Oxidative phosphorylation_Homo sapiens_hsa00190 | 6.74153740 |
2 | Parkinsons disease_Homo sapiens_hsa05012 | 5.63313226 |
3 | Alzheimers disease_Homo sapiens_hsa05010 | 4.52014082 |
4 | Huntingtons disease_Homo sapiens_hsa05016 | 3.96370017 |
5 | * Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 3.48879102 |
6 | * Cardiac muscle contraction_Homo sapiens_hsa04260 | 3.16866316 |
7 | Ribosome_Homo sapiens_hsa03010 | 3.11566347 |
8 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 2.29861561 |
9 | Proteasome_Homo sapiens_hsa03050 | 2.12599387 |
10 | Nicotine addiction_Homo sapiens_hsa05033 | 2.11579134 |
11 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.98836448 |
12 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.97865984 |
13 | Protein export_Homo sapiens_hsa03060 | 1.91538006 |
14 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.65293157 |
15 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.53635197 |
16 | Mismatch repair_Homo sapiens_hsa03430 | 1.52478033 |
17 | Homologous recombination_Homo sapiens_hsa03440 | 1.51696755 |
18 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.39391391 |
19 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 1.39299480 |
20 | Serotonergic synapse_Homo sapiens_hsa04726 | 1.38470009 |
21 | RNA polymerase_Homo sapiens_hsa03020 | 1.34697491 |
22 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.33713249 |
23 | GABAergic synapse_Homo sapiens_hsa04727 | 1.33543203 |
24 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.30524682 |
25 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.25867161 |
26 | Basal transcription factors_Homo sapiens_hsa03022 | 1.20212403 |
27 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.18263678 |
28 | DNA replication_Homo sapiens_hsa03030 | 1.16642319 |
29 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.15346377 |
30 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 1.15317966 |
31 | Taste transduction_Homo sapiens_hsa04742 | 1.14527667 |
32 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 1.14175203 |
33 | Spliceosome_Homo sapiens_hsa03040 | 1.12039352 |
34 | Glutamatergic synapse_Homo sapiens_hsa04724 | 1.11782230 |
35 | Morphine addiction_Homo sapiens_hsa05032 | 1.11478882 |
36 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.10898383 |
37 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.10883290 |
38 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.10068815 |
39 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.05600426 |
40 | RNA degradation_Homo sapiens_hsa03018 | 1.04104056 |
41 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.97799758 |
42 | Phototransduction_Homo sapiens_hsa04744 | 0.97529313 |
43 | Circadian entrainment_Homo sapiens_hsa04713 | 0.95616165 |
44 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.92563677 |
45 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.90483176 |
46 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.89717745 |
47 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.89311159 |
48 | Dopaminergic synapse_Homo sapiens_hsa04728 | 0.88906480 |
49 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.86512113 |
50 | Renin secretion_Homo sapiens_hsa04924 | 0.84078738 |
51 | Long-term potentiation_Homo sapiens_hsa04720 | 0.82040817 |
52 | Long-term depression_Homo sapiens_hsa04730 | 0.78422465 |
53 | Base excision repair_Homo sapiens_hsa03410 | 0.78329965 |
54 | Metabolic pathways_Homo sapiens_hsa01100 | 0.78263009 |
55 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.77514337 |
56 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.76056982 |
57 | Salivary secretion_Homo sapiens_hsa04970 | 0.75755238 |
58 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.73027713 |
59 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.71406210 |
60 | Sulfur relay system_Homo sapiens_hsa04122 | 0.70229288 |
61 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.67837589 |
62 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.65954221 |
63 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 0.65883102 |
64 | RNA transport_Homo sapiens_hsa03013 | 0.64740493 |
65 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 0.62733060 |
66 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.61988651 |
67 | Olfactory transduction_Homo sapiens_hsa04740 | 0.61598074 |
68 | Cocaine addiction_Homo sapiens_hsa05030 | 0.61111358 |
69 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.59952431 |
70 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.59816879 |
71 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.59519434 |
72 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.59324155 |
73 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 0.58759506 |
74 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.58470711 |
75 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.56567426 |
76 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.56120536 |
77 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.55370845 |
78 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.54771006 |
79 | Axon guidance_Homo sapiens_hsa04360 | 0.54077145 |
80 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52809639 |
81 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 0.51741555 |
82 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.51376243 |
83 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.50871116 |
84 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.50669495 |
85 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 0.50223033 |
86 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.47960465 |
87 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.47121568 |
88 | Retinol metabolism_Homo sapiens_hsa00830 | 0.46984512 |
89 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.46673260 |
90 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.45893709 |
91 | Histidine metabolism_Homo sapiens_hsa00340 | 0.45822695 |
92 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.44407916 |
93 | Gap junction_Homo sapiens_hsa04540 | 0.42153943 |
94 | Insulin secretion_Homo sapiens_hsa04911 | 0.42041087 |
95 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.41442392 |
96 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.39740895 |
97 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.39076003 |
98 | Carbon metabolism_Homo sapiens_hsa01200 | 0.38152874 |
99 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.37803319 |
100 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.37610229 |
101 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.36408717 |
102 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.36325015 |
103 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.36094321 |
104 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 0.35708728 |
105 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.33302668 |
106 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.32731483 |
107 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.30521401 |
108 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.30318219 |
109 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.30297876 |
110 | Alcoholism_Homo sapiens_hsa05034 | 0.30161850 |
111 | Phagosome_Homo sapiens_hsa04145 | 0.30138084 |
112 | Purine metabolism_Homo sapiens_hsa00230 | 0.29593739 |
113 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.29564140 |
114 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 0.29166605 |
115 | Peroxisome_Homo sapiens_hsa04146 | 0.27974960 |
116 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.27112871 |
117 | Melanogenesis_Homo sapiens_hsa04916 | 0.27097203 |
118 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.25764158 |
119 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.25148276 |
120 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.25145773 |
121 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.25049095 |
122 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.24772086 |
123 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.24585002 |
124 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.24302770 |
125 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.21918551 |
126 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.20329724 |
127 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 0.19234283 |
128 | Mineral absorption_Homo sapiens_hsa04978 | 0.18557210 |
129 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.18491901 |
130 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.17682039 |
131 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.17142391 |
132 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.16726925 |
133 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.13861808 |
134 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.12800746 |
135 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.11378159 |