

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | pyrimidine ribonucleoside monophosphate biosynthetic process (GO:0009174) | 6.40344130 |
| 2 | UMP metabolic process (GO:0046049) | 6.40344130 |
| 3 | pyrimidine ribonucleoside monophosphate metabolic process (GO:0009173) | 6.40344130 |
| 4 | UMP biosynthetic process (GO:0006222) | 6.40344130 |
| 5 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 6.08630833 |
| 6 | nucleotide salvage (GO:0043173) | 5.68234584 |
| 7 | maturation of SSU-rRNA (GO:0030490) | 5.57274663 |
| 8 | pyrimidine-containing compound salvage (GO:0008655) | 5.45232880 |
| 9 | pyrimidine nucleoside salvage (GO:0043097) | 5.45232880 |
| 10 | inner ear receptor cell differentiation (GO:0060113) | 5.40121512 |
| 11 | behavioral response to nicotine (GO:0035095) | 5.12298865 |
| 12 | mitochondrion transport along microtubule (GO:0047497) | 5.08998858 |
| 13 | establishment of mitochondrion localization, microtubule-mediated (GO:0034643) | 5.08998858 |
| 14 | establishment of mitochondrion localization (GO:0051654) | 5.04340400 |
| 15 | pyrimidine nucleoside monophosphate biosynthetic process (GO:0009130) | 5.02896616 |
| 16 | pyrimidine nucleoside monophosphate metabolic process (GO:0009129) | 4.89015125 |
| 17 | nucleoside salvage (GO:0043174) | 4.77359951 |
| 18 | pentose metabolic process (GO:0019321) | 4.63536754 |
| 19 | pyrimidine nucleobase catabolic process (GO:0006208) | 4.63120574 |
| 20 | regulation of glycogen (starch) synthase activity (GO:2000465) | 4.54037101 |
| 21 | head development (GO:0060322) | 4.47204588 |
| 22 | viral transcription (GO:0019083) | 4.36240540 |
| 23 | calcium ion-dependent exocytosis (GO:0017156) | 4.35424428 |
| 24 | ribosomal small subunit assembly (GO:0000028) | 4.32166907 |
| 25 | translational termination (GO:0006415) | 4.26020673 |
| 26 | mechanoreceptor differentiation (GO:0042490) | 4.22923387 |
| 27 | regulation of cilium movement (GO:0003352) | 4.13918479 |
| 28 | CTP metabolic process (GO:0046036) | 4.05846789 |
| 29 | CTP biosynthetic process (GO:0006241) | 4.05846789 |
| 30 | keratinocyte development (GO:0003334) | 4.01650684 |
| 31 | cell-cell junction maintenance (GO:0045217) | 4.00434455 |
| 32 | terpenoid biosynthetic process (GO:0016114) | 3.89355426 |
| 33 | diterpenoid biosynthetic process (GO:0016102) | 3.83153892 |
| 34 | nucleobase catabolic process (GO:0046113) | 3.77819220 |
| 35 | translational elongation (GO:0006414) | 3.73181054 |
| 36 | photoreceptor cell maintenance (GO:0045494) | 3.66120408 |
| 37 | epithelial cilium movement (GO:0003351) | 3.64153643 |
| 38 | pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209) | 3.58803071 |
| 39 | regulation of microtubule-based movement (GO:0060632) | 3.50285956 |
| 40 | cell proliferation in forebrain (GO:0021846) | 3.46675554 |
| 41 | ribosomal small subunit biogenesis (GO:0042274) | 3.45447467 |
| 42 | pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208) | 3.39824976 |
| 43 | cellular protein complex disassembly (GO:0043624) | 3.38050662 |
| 44 | activation of NF-kappaB-inducing kinase activity (GO:0007250) | 3.35089455 |
| 45 | cell junction maintenance (GO:0034331) | 3.34856012 |
| 46 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 3.31209790 |
| 47 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 3.31209790 |
| 48 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.28738812 |
| 49 | cotranslational protein targeting to membrane (GO:0006613) | 3.22147396 |
| 50 | protein targeting to ER (GO:0045047) | 3.20572537 |
| 51 | catecholamine transport (GO:0051937) | 3.17813836 |
| 52 | axoneme assembly (GO:0035082) | 3.16250110 |
| 53 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 3.12809764 |
| 54 | protein polyglutamylation (GO:0018095) | 3.08188264 |
| 55 | viral life cycle (GO:0019058) | 3.07399948 |
| 56 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 3.06953265 |
| 57 | positive regulation of sodium ion transmembrane transporter activity (GO:2000651) | 3.05113084 |
| 58 | auditory receptor cell differentiation (GO:0042491) | 3.04947642 |
| 59 | postsynaptic membrane organization (GO:0001941) | 3.01798139 |
| 60 | glyoxylate metabolic process (GO:0046487) | 2.98962053 |
| 61 | positive regulation of calcium ion-dependent exocytosis (GO:0045956) | 2.98499727 |
| 62 | pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148) | 2.97462379 |
| 63 | acrosome reaction (GO:0007340) | 2.97280802 |
| 64 | synaptic transmission, cholinergic (GO:0007271) | 2.96537955 |
| 65 | regulation of inhibitory postsynaptic membrane potential (GO:0060080) | 2.96264016 |
| 66 | protein localization to endoplasmic reticulum (GO:0070972) | 2.95481469 |
| 67 | pyrimidine ribonucleoside biosynthetic process (GO:0046132) | 2.93959008 |
| 68 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.92301193 |
| 69 | regulation of activation of Janus kinase activity (GO:0010533) | 2.92011204 |
| 70 | protein complex disassembly (GO:0043241) | 2.86083508 |
| 71 | camera-type eye morphogenesis (GO:0048593) | 2.84612516 |
| 72 | peptidyl-lysine trimethylation (GO:0018023) | 2.84005403 |
| 73 | axonemal dynein complex assembly (GO:0070286) | 2.81764653 |
| 74 | pyrimidine ribonucleotide biosynthetic process (GO:0009220) | 2.76501174 |
| 75 | parturition (GO:0007567) | 2.75994092 |
| 76 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.74963382 |
| 77 | macromolecular complex disassembly (GO:0032984) | 2.73263006 |
| 78 | transmission of nerve impulse (GO:0019226) | 2.70160271 |
| 79 | regulation of meiosis I (GO:0060631) | 2.68357003 |
| 80 | oxidative demethylation (GO:0070989) | 2.67961589 |
| 81 | sperm motility (GO:0030317) | 2.61460391 |
| 82 | drug catabolic process (GO:0042737) | 2.59582951 |
| 83 | cilium movement (GO:0003341) | 2.58871283 |
| 84 | positive regulation of meiosis (GO:0045836) | 2.58456220 |
| 85 | phenylpropanoid metabolic process (GO:0009698) | 2.57581273 |
| 86 | protein-chromophore linkage (GO:0018298) | 2.57159785 |
| 87 | pyrimidine nucleoside triphosphate metabolic process (GO:0009147) | 2.55888364 |
| 88 | peptidyl-cysteine modification (GO:0018198) | 2.51563973 |
| 89 | positive regulation of sodium ion transmembrane transport (GO:1902307) | 2.51435248 |
| 90 | pyrimidine ribonucleotide metabolic process (GO:0009218) | 2.50980316 |
| 91 | negative regulation of telomere maintenance (GO:0032205) | 2.49315982 |
| 92 | dopamine transport (GO:0015872) | 2.48624237 |
| 93 | DNA dealkylation (GO:0035510) | 2.48363375 |
| 94 | neuronal action potential (GO:0019228) | 2.47519937 |
| 95 | negative regulation of sodium ion transport (GO:0010766) | 2.46922920 |
| 96 | phosphorelay signal transduction system (GO:0000160) | 2.46338428 |
| 97 | somite development (GO:0061053) | 2.45224238 |
| 98 | neuromuscular synaptic transmission (GO:0007274) | 2.43370640 |
| 99 | positive regulation of NIK/NF-kappaB signaling (GO:1901224) | 2.42938106 |
| 100 | organic cation transport (GO:0015695) | 2.42673064 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | EZH2_22144423_ChIP-Seq_EOC_Human | 5.43544948 |
| 2 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 3.06999387 |
| 3 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.81291293 |
| 4 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 2.40401949 |
| 5 | REST_21632747_ChIP-Seq_MESCs_Mouse | 2.30373112 |
| 6 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.22335789 |
| 7 | VDR_22108803_ChIP-Seq_LS180_Human | 2.19304736 |
| 8 | NR4A2_19515692_ChIP-ChIP_MN9D_Mouse | 2.12562358 |
| 9 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.04683363 |
| 10 | CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons | 1.91776492 |
| 11 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.90678861 |
| 12 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.86147077 |
| 13 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.85197818 |
| 14 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.84853501 |
| 15 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.80800126 |
| 16 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.78814969 |
| 17 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.75992345 |
| 18 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.75771511 |
| 19 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.71278408 |
| 20 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 1.69636858 |
| 21 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.69047149 |
| 22 | REST_18959480_ChIP-ChIP_MESCs_Mouse | 1.68830883 |
| 23 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.68719728 |
| 24 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.64935927 |
| 25 | P53_22127205_ChIP-Seq_FIBROBLAST_Human | 1.61825994 |
| 26 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.60673478 |
| 27 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.60190223 |
| 28 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.58581241 |
| 29 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.55951912 |
| 30 | RNF2_27304074_Chip-Seq_NSC_Mouse | 1.52031080 |
| 31 | FUS_26573619_Chip-Seq_HEK293_Human | 1.51292412 |
| 32 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.48618589 |
| 33 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.47146133 |
| 34 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.45483953 |
| 35 | SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.44746761 |
| 36 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 1.41379886 |
| 37 | P300_19829295_ChIP-Seq_ESCs_Human | 1.40635522 |
| 38 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.40432403 |
| 39 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.39020551 |
| 40 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.37645358 |
| 41 | ERA_21632823_ChIP-Seq_H3396_Human | 1.33453674 |
| 42 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.33194912 |
| 43 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.33059784 |
| 44 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 1.31801955 |
| 45 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 1.31801955 |
| 46 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 1.30674854 |
| 47 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.26531609 |
| 48 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.26237458 |
| 49 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.26237458 |
| 50 | TP53_22573176_ChIP-Seq_HFKS_Human | 1.26012872 |
| 51 | SIN3B_21632747_ChIP-Seq_MESCs_Mouse | 1.22897218 |
| 52 | WDR5_24793694_ChIP-Seq_LNCAP_Human | 1.21973694 |
| 53 | SMAD3_21741376_ChIP-Seq_ESCs_Human | 1.20393287 |
| 54 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.19881724 |
| 55 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.19074230 |
| 56 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.17452732 |
| 57 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.17286378 |
| 58 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 1.17111285 |
| 59 | AR_20517297_ChIP-Seq_VCAP_Human | 1.16192079 |
| 60 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 1.15793284 |
| 61 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 1.14263328 |
| 62 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.14109114 |
| 63 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.13883635 |
| 64 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.13790849 |
| 65 | TCF4_23295773_ChIP-Seq_U87_Human | 1.12671569 |
| 66 | EWS_26573619_Chip-Seq_HEK293_Human | 1.11243456 |
| 67 | NCOR_22424771_ChIP-Seq_293T_Human | 1.09767923 |
| 68 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.09659186 |
| 69 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.09197940 |
| 70 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.09104157 |
| 71 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.08574275 |
| 72 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.08507629 |
| 73 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.08450195 |
| 74 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.08129849 |
| 75 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.08056681 |
| 76 | E2F1_20622854_ChIP-Seq_HELA_Human | 1.07820945 |
| 77 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 1.06848353 |
| 78 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.06816780 |
| 79 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.06581381 |
| 80 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 1.06404386 |
| 81 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.05387965 |
| 82 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.05155311 |
| 83 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.04855523 |
| 84 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.02036934 |
| 85 | RCOR3_21632747_ChIP-Seq_MESCs_Mouse | 1.01948202 |
| 86 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.01809792 |
| 87 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.00358701 |
| 88 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.00358701 |
| 89 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 0.99740565 |
| 90 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.99167161 |
| 91 | STAT3_23295773_ChIP-Seq_U87_Human | 0.98775976 |
| 92 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.98764763 |
| 93 | RAC3_21632823_ChIP-Seq_H3396_Human | 0.98658010 |
| 94 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 0.98169641 |
| 95 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 0.96749336 |
| 96 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 0.95439251 |
| 97 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 0.95400767 |
| 98 | JUN_21703547_ChIP-Seq_K562_Human | 0.94972127 |
| 99 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 0.94173151 |
| 100 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 0.93787563 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0001485_abnormal_pinna_reflex | 3.69739979 |
| 2 | MP0003646_muscle_fatigue | 3.67614327 |
| 3 | MP0006292_abnormal_olfactory_placode | 3.09523356 |
| 4 | MP0004742_abnormal_vestibular_system | 3.02335632 |
| 5 | MP0006276_abnormal_autonomic_nervous | 2.93110414 |
| 6 | MP0008875_abnormal_xenobiotic_pharmacok | 2.80703822 |
| 7 | MP0003122_maternal_imprinting | 2.60645988 |
| 8 | MP0009379_abnormal_foot_pigmentation | 2.43610521 |
| 9 | MP0003787_abnormal_imprinting | 2.37365932 |
| 10 | MP0002163_abnormal_gland_morphology | 2.37037189 |
| 11 | MP0003136_yellow_coat_color | 2.30786018 |
| 12 | MP0003880_abnormal_central_pattern | 2.18650304 |
| 13 | MP0001293_anophthalmia | 2.06511666 |
| 14 | MP0001529_abnormal_vocalization | 2.05229632 |
| 15 | MP0003879_abnormal_hair_cell | 1.99509517 |
| 16 | MP0008872_abnormal_physiological_respon | 1.91934600 |
| 17 | MP0000778_abnormal_nervous_system | 1.85399738 |
| 18 | MP0008877_abnormal_DNA_methylation | 1.85130666 |
| 19 | MP0004142_abnormal_muscle_tone | 1.84576179 |
| 20 | MP0001986_abnormal_taste_sensitivity | 1.84212151 |
| 21 | MP0004885_abnormal_endolymph | 1.72599357 |
| 22 | MP0002735_abnormal_chemical_nociception | 1.68783589 |
| 23 | MP0003121_genomic_imprinting | 1.67567375 |
| 24 | MP0004133_heterotaxia | 1.65650436 |
| 25 | MP0003878_abnormal_ear_physiology | 1.65457916 |
| 26 | MP0005377_hearing/vestibular/ear_phenot | 1.65457916 |
| 27 | MP0004270_analgesia | 1.61453471 |
| 28 | MP0009745_abnormal_behavioral_response | 1.60188180 |
| 29 | MP0003123_paternal_imprinting | 1.58300536 |
| 30 | MP0002272_abnormal_nervous_system | 1.56590966 |
| 31 | MP0002734_abnormal_mechanical_nocicepti | 1.50070571 |
| 32 | MP0005360_urolithiasis | 1.48119373 |
| 33 | MP0005646_abnormal_pituitary_gland | 1.46400887 |
| 34 | MP0009046_muscle_twitch | 1.46314934 |
| 35 | MP0008789_abnormal_olfactory_epithelium | 1.46221639 |
| 36 | MP0001968_abnormal_touch/_nociception | 1.46112506 |
| 37 | MP0000372_irregular_coat_pigmentation | 1.43286970 |
| 38 | MP0002638_abnormal_pupillary_reflex | 1.41236234 |
| 39 | MP0002736_abnormal_nociception_after | 1.36197627 |
| 40 | MP0003635_abnormal_synaptic_transmissio | 1.35659689 |
| 41 | MP0005379_endocrine/exocrine_gland_phen | 1.33790312 |
| 42 | MP0002876_abnormal_thyroid_physiology | 1.32859989 |
| 43 | MP0002160_abnormal_reproductive_system | 1.28543397 |
| 44 | MP0001486_abnormal_startle_reflex | 1.26526667 |
| 45 | MP0002067_abnormal_sensory_capabilities | 1.24578469 |
| 46 | MP0005499_abnormal_olfactory_system | 1.23999290 |
| 47 | MP0005394_taste/olfaction_phenotype | 1.23999290 |
| 48 | MP0000631_abnormal_neuroendocrine_gland | 1.22999017 |
| 49 | MP0002557_abnormal_social/conspecific_i | 1.22329926 |
| 50 | MP0002653_abnormal_ependyma_morphology | 1.21882585 |
| 51 | MP0001346_abnormal_lacrimal_gland | 1.21457491 |
| 52 | MP0004145_abnormal_muscle_electrophysio | 1.21411204 |
| 53 | MP0001348_abnormal_lacrimal_gland | 1.20611521 |
| 54 | MP0005645_abnormal_hypothalamus_physiol | 1.20386497 |
| 55 | MP0010386_abnormal_urinary_bladder | 1.20117756 |
| 56 | MP0005551_abnormal_eye_electrophysiolog | 1.19847277 |
| 57 | MP0002938_white_spotting | 1.19173636 |
| 58 | MP0003195_calcinosis | 1.18562304 |
| 59 | MP0001970_abnormal_pain_threshold | 1.18127731 |
| 60 | MP0001963_abnormal_hearing_physiology | 1.17036760 |
| 61 | MP0000026_abnormal_inner_ear | 1.14934392 |
| 62 | MP0002063_abnormal_learning/memory/cond | 1.14686085 |
| 63 | MP0000955_abnormal_spinal_cord | 1.13814056 |
| 64 | MP0005167_abnormal_blood-brain_barrier | 1.10232725 |
| 65 | MP0002095_abnormal_skin_pigmentation | 1.06757947 |
| 66 | MP0000538_abnormal_urinary_bladder | 1.06638195 |
| 67 | MP0002572_abnormal_emotion/affect_behav | 1.04452892 |
| 68 | MP0005389_reproductive_system_phenotype | 1.04049418 |
| 69 | MP0002752_abnormal_somatic_nervous | 1.03673073 |
| 70 | MP0002064_seizures | 1.03356469 |
| 71 | MP0001984_abnormal_olfaction | 1.02227006 |
| 72 | MP0005423_abnormal_somatic_nervous | 1.02218181 |
| 73 | MP0005085_abnormal_gallbladder_physiolo | 1.02019057 |
| 74 | MP0002733_abnormal_thermal_nociception | 1.01745491 |
| 75 | MP0000427_abnormal_hair_cycle | 0.98993095 |
| 76 | MP0002882_abnormal_neuron_morphology | 0.98008587 |
| 77 | MP0004859_abnormal_synaptic_plasticity | 0.97952071 |
| 78 | MP0002102_abnormal_ear_morphology | 0.96509494 |
| 79 | MP0001905_abnormal_dopamine_level | 0.91482928 |
| 80 | MP0004043_abnormal_pH_regulation | 0.89595892 |
| 81 | MP0005195_abnormal_posterior_eye | 0.89569134 |
| 82 | MP0008775_abnormal_heart_ventricle | 0.88734621 |
| 83 | MP0004924_abnormal_behavior | 0.88371816 |
| 84 | MP0005386_behavior/neurological_phenoty | 0.88371816 |
| 85 | MP0002277_abnormal_respiratory_mucosa | 0.88270832 |
| 86 | MP0005310_abnormal_salivary_gland | 0.87031551 |
| 87 | MP0001919_abnormal_reproductive_system | 0.86119435 |
| 88 | MP0003942_abnormal_urinary_system | 0.83882485 |
| 89 | MP0005391_vision/eye_phenotype | 0.79962275 |
| 90 | MP0000049_abnormal_middle_ear | 0.79954189 |
| 91 | MP0002234_abnormal_pharynx_morphology | 0.79561753 |
| 92 | MP0002229_neurodegeneration | 0.79305086 |
| 93 | MP0003698_abnormal_male_reproductive | 0.76645623 |
| 94 | MP0006072_abnormal_retinal_apoptosis | 0.76593081 |
| 95 | MP0002152_abnormal_brain_morphology | 0.75868666 |
| 96 | MP0002184_abnormal_innervation | 0.75050599 |
| 97 | MP0002837_dystrophic_cardiac_calcinosis | 0.73644417 |
| 98 | MP0003252_abnormal_bile_duct | 0.73605866 |
| 99 | MP0002909_abnormal_adrenal_gland | 0.73298500 |
| 100 | MP0005174_abnormal_tail_pigmentation | 0.71494704 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Hip dysplasia (HP:0001385) | 4.70216432 |
| 2 | Hypoplasia of the pons (HP:0012110) | 4.58752939 |
| 3 | Abnormality of the pons (HP:0007361) | 4.04463877 |
| 4 | Reticulocytopenia (HP:0001896) | 3.90953877 |
| 5 | Chronic hepatic failure (HP:0100626) | 3.80791803 |
| 6 | Difficulty running (HP:0009046) | 3.62513288 |
| 7 | Type II lissencephaly (HP:0007260) | 3.56211952 |
| 8 | Abnormality of midbrain morphology (HP:0002418) | 3.34392337 |
| 9 | Molar tooth sign on MRI (HP:0002419) | 3.34392337 |
| 10 | Pancreatic fibrosis (HP:0100732) | 3.31841559 |
| 11 | Acute necrotizing encephalopathy (HP:0006965) | 2.98373682 |
| 12 | Hip contracture (HP:0003273) | 2.94148897 |
| 13 | Cerebellar dysplasia (HP:0007033) | 2.92425821 |
| 14 | Bifid tongue (HP:0010297) | 2.91927496 |
| 15 | Pancreatic cysts (HP:0001737) | 2.88911671 |
| 16 | Poor suck (HP:0002033) | 2.87859994 |
| 17 | Hyperglycinemia (HP:0002154) | 2.76668174 |
| 18 | Abnormality of the renal medulla (HP:0100957) | 2.75901260 |
| 19 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.65892165 |
| 20 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.65892165 |
| 21 | Limited hip movement (HP:0008800) | 2.62893178 |
| 22 | Anophthalmia (HP:0000528) | 2.58625423 |
| 23 | Acute encephalopathy (HP:0006846) | 2.56390519 |
| 24 | Abnormal mitochondria in muscle tissue (HP:0008316) | 2.49752962 |
| 25 | Papilledema (HP:0001085) | 2.48919149 |
| 26 | Anterior segment dysgenesis (HP:0007700) | 2.47611457 |
| 27 | Progressive macrocephaly (HP:0004481) | 2.46833149 |
| 28 | Oligodactyly (hands) (HP:0001180) | 2.46561036 |
| 29 | Septo-optic dysplasia (HP:0100842) | 2.45692627 |
| 30 | Fetal akinesia sequence (HP:0001989) | 2.43740135 |
| 31 | Pendular nystagmus (HP:0012043) | 2.42588896 |
| 32 | Morphological abnormality of the middle ear (HP:0008609) | 2.42037659 |
| 33 | Hypoplasia of the brainstem (HP:0002365) | 2.41093899 |
| 34 | Aplasia/Hypoplasia of the brainstem (HP:0007362) | 2.41093899 |
| 35 | True hermaphroditism (HP:0010459) | 2.40933643 |
| 36 | Retinal dysplasia (HP:0007973) | 2.39019704 |
| 37 | Nephronophthisis (HP:0000090) | 2.35907803 |
| 38 | Genital tract atresia (HP:0001827) | 2.35339057 |
| 39 | Polyphagia (HP:0002591) | 2.34263873 |
| 40 | Aplasia/Hypoplasia of the sternum (HP:0006714) | 2.33637715 |
| 41 | Tubular atrophy (HP:0000092) | 2.33404254 |
| 42 | Chorioretinal atrophy (HP:0000533) | 2.32394315 |
| 43 | Tubulointerstitial nephritis (HP:0001970) | 2.31239417 |
| 44 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.31025179 |
| 45 | Optic nerve hypoplasia (HP:0000609) | 2.30115672 |
| 46 | Mitochondrial inheritance (HP:0001427) | 2.29904078 |
| 47 | Bilateral microphthalmos (HP:0007633) | 2.27019283 |
| 48 | Restlessness (HP:0000711) | 2.26084878 |
| 49 | Vaginal atresia (HP:0000148) | 2.20803661 |
| 50 | Abnormality of the renal cortex (HP:0011035) | 2.17459727 |
| 51 | Increased CSF lactate (HP:0002490) | 2.15814731 |
| 52 | Congenital stationary night blindness (HP:0007642) | 2.14716731 |
| 53 | Renal dysplasia (HP:0000110) | 2.14232281 |
| 54 | Renovascular hypertension (HP:0100817) | 2.12679125 |
| 55 | Absent thumb (HP:0009777) | 2.12270123 |
| 56 | Dyskinesia (HP:0100660) | 2.11789343 |
| 57 | Lissencephaly (HP:0001339) | 2.11469635 |
| 58 | Hypoplasia of the ulna (HP:0003022) | 2.10574868 |
| 59 | Ectopic kidney (HP:0000086) | 2.10465888 |
| 60 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 2.09444167 |
| 61 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.06219855 |
| 62 | Oligodactyly (HP:0012165) | 2.05458512 |
| 63 | Abnormality of the diencephalon (HP:0010662) | 2.04405169 |
| 64 | Cystic liver disease (HP:0006706) | 2.01277202 |
| 65 | Optic disc pallor (HP:0000543) | 1.95789570 |
| 66 | Volvulus (HP:0002580) | 1.95345316 |
| 67 | Wide intermamillary distance (HP:0006610) | 1.95282274 |
| 68 | Medial flaring of the eyebrow (HP:0010747) | 1.93517383 |
| 69 | Polydipsia (HP:0001959) | 1.92440136 |
| 70 | Abnormal drinking behavior (HP:0030082) | 1.92440136 |
| 71 | Agitation (HP:0000713) | 1.91655689 |
| 72 | Renal hypoplasia (HP:0000089) | 1.91492694 |
| 73 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 1.90871908 |
| 74 | Optic nerve coloboma (HP:0000588) | 1.90211057 |
| 75 | Broad-based gait (HP:0002136) | 1.90093922 |
| 76 | Achilles tendon contracture (HP:0001771) | 1.88446990 |
| 77 | Abnormality of the labia minora (HP:0012880) | 1.87602399 |
| 78 | Pachygyria (HP:0001302) | 1.87501499 |
| 79 | Abnormality of the pubic bones (HP:0003172) | 1.87372891 |
| 80 | Short femoral neck (HP:0100864) | 1.86854772 |
| 81 | Tubulointerstitial abnormality (HP:0001969) | 1.85225008 |
| 82 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 1.85024051 |
| 83 | Asplenia (HP:0001746) | 1.84229829 |
| 84 | Sclerocornea (HP:0000647) | 1.83654758 |
| 85 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.83283925 |
| 86 | Absent/shortened dynein arms (HP:0200106) | 1.83283925 |
| 87 | Rib fusion (HP:0000902) | 1.82419929 |
| 88 | Cerebral edema (HP:0002181) | 1.79509498 |
| 89 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 1.78821601 |
| 90 | Spastic tetraplegia (HP:0002510) | 1.78575304 |
| 91 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.78110242 |
| 92 | Abnormality of the aortic arch (HP:0012303) | 1.76891587 |
| 93 | Adrenal hypoplasia (HP:0000835) | 1.75804333 |
| 94 | Decreased central vision (HP:0007663) | 1.75400718 |
| 95 | Abnormality of the Achilles tendon (HP:0005109) | 1.75057162 |
| 96 | Increased hepatocellular lipid droplets (HP:0006565) | 1.74971498 |
| 97 | Bicornuate uterus (HP:0000813) | 1.73570857 |
| 98 | Potter facies (HP:0002009) | 1.73316739 |
| 99 | Facial shape deformation (HP:0011334) | 1.73316739 |
| 100 | Impaired smooth pursuit (HP:0007772) | 1.72804994 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | SIK2 | 5.93714884 |
| 2 | WNK3 | 5.07683612 |
| 3 | FRK | 3.99564085 |
| 4 | LIMK1 | 3.65454391 |
| 5 | WNK4 | 2.92687133 |
| 6 | NTRK2 | 2.83872327 |
| 7 | PRKD3 | 2.64064897 |
| 8 | CASK | 2.54068613 |
| 9 | NTRK1 | 2.42567881 |
| 10 | NEK2 | 2.23803817 |
| 11 | STK39 | 1.90814355 |
| 12 | TNIK | 1.84321515 |
| 13 | MAP4K2 | 1.82739386 |
| 14 | DYRK2 | 1.61276004 |
| 15 | PINK1 | 1.59928697 |
| 16 | NUAK1 | 1.58250902 |
| 17 | NTRK3 | 1.56309031 |
| 18 | MAP3K11 | 1.46841078 |
| 19 | PRKCG | 1.46276021 |
| 20 | MAP2K7 | 1.41720211 |
| 21 | TAF1 | 1.39390114 |
| 22 | MARK1 | 1.37906679 |
| 23 | MINK1 | 1.35754908 |
| 24 | GRK1 | 1.35275861 |
| 25 | TRIM28 | 1.30495066 |
| 26 | ADRBK2 | 1.26699209 |
| 27 | PLK2 | 1.16906624 |
| 28 | MAPK13 | 1.16142680 |
| 29 | INSRR | 1.14406546 |
| 30 | PKN1 | 1.08629447 |
| 31 | SIK3 | 1.06140042 |
| 32 | BCKDK | 1.03813352 |
| 33 | OXSR1 | 1.02477183 |
| 34 | CDK19 | 1.01601095 |
| 35 | SGK223 | 0.98904001 |
| 36 | SGK494 | 0.98904001 |
| 37 | PAK3 | 0.97073780 |
| 38 | NLK | 0.89395274 |
| 39 | STK11 | 0.85643403 |
| 40 | DYRK1A | 0.84166892 |
| 41 | TIE1 | 0.83535650 |
| 42 | CAMK1 | 0.80403012 |
| 43 | PRKCQ | 0.78998855 |
| 44 | TESK1 | 0.78827148 |
| 45 | BMPR1B | 0.77780479 |
| 46 | PIK3CA | 0.75219881 |
| 47 | MUSK | 0.72755817 |
| 48 | ACVR1B | 0.67851814 |
| 49 | BCR | 0.66084749 |
| 50 | SGK2 | 0.65629100 |
| 51 | MAP3K4 | 0.65114965 |
| 52 | MAP4K1 | 0.64608561 |
| 53 | WNK1 | 0.64550641 |
| 54 | PIK3CG | 0.64093951 |
| 55 | TLK1 | 0.63910831 |
| 56 | PLK4 | 0.63382953 |
| 57 | PRKCH | 0.62331904 |
| 58 | PHKG2 | 0.60033401 |
| 59 | PHKG1 | 0.60033401 |
| 60 | CSNK1A1 | 0.56952768 |
| 61 | PRKCE | 0.54571303 |
| 62 | CDC42BPA | 0.53458457 |
| 63 | ABL2 | 0.52207870 |
| 64 | CDK5 | 0.50095649 |
| 65 | PRKCZ | 0.48406865 |
| 66 | EPHA4 | 0.48214075 |
| 67 | CSNK1G1 | 0.48012869 |
| 68 | PRKACA | 0.47298629 |
| 69 | TYRO3 | 0.47180818 |
| 70 | LRRK2 | 0.46262110 |
| 71 | PRKCA | 0.45509872 |
| 72 | ADRBK1 | 0.44645503 |
| 73 | RPS6KA5 | 0.43355396 |
| 74 | KDR | 0.41323511 |
| 75 | CAMK1G | 0.40965304 |
| 76 | CSNK1E | 0.40755132 |
| 77 | CAMKK2 | 0.40534319 |
| 78 | OBSCN | 0.40017375 |
| 79 | CSNK2A2 | 0.39393198 |
| 80 | MAP3K9 | 0.38230675 |
| 81 | EPHB2 | 0.37792029 |
| 82 | DYRK1B | 0.37410009 |
| 83 | CSNK1G2 | 0.37038492 |
| 84 | SGK3 | 0.36962433 |
| 85 | ERBB2 | 0.35348701 |
| 86 | PBK | 0.34396086 |
| 87 | CAMK2A | 0.34373062 |
| 88 | PRKG1 | 0.33150884 |
| 89 | PNCK | 0.33036179 |
| 90 | AKT1 | 0.32590998 |
| 91 | SGK1 | 0.32289223 |
| 92 | PRKCD | 0.30915416 |
| 93 | PAK1 | 0.29862639 |
| 94 | PRKAA2 | 0.29596830 |
| 95 | MATK | 0.28932974 |
| 96 | LCK | 0.27943174 |
| 97 | STK38 | 0.27528881 |
| 98 | PRKAA1 | 0.27461378 |
| 99 | AURKA | 0.27346469 |
| 100 | RPS6KA3 | 0.26969349 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Sulfur relay system_Homo sapiens_hsa04122 | 4.83995370 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.88091576 |
| 3 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.83701264 |
| 4 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 2.55690808 |
| 5 | Nicotine addiction_Homo sapiens_hsa05033 | 2.36080031 |
| 6 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 2.24973571 |
| 7 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.19967049 |
| 8 | Butanoate metabolism_Homo sapiens_hsa00650 | 2.16906414 |
| 9 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 2.11846166 |
| 10 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.06495660 |
| 11 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.05246203 |
| 12 | Phototransduction_Homo sapiens_hsa04744 | 1.92572574 |
| 13 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.91097346 |
| 14 | Parkinsons disease_Homo sapiens_hsa05012 | 1.86151227 |
| 15 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.85402462 |
| 16 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.75825527 |
| 17 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 1.71606197 |
| 18 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.58465658 |
| 19 | Morphine addiction_Homo sapiens_hsa05032 | 1.54664596 |
| 20 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.50554338 |
| 21 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.46878184 |
| 22 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.45206921 |
| 23 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.44546735 |
| 24 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.44543309 |
| 25 | Huntingtons disease_Homo sapiens_hsa05016 | 1.40359018 |
| 26 | Olfactory transduction_Homo sapiens_hsa04740 | 1.34051467 |
| 27 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.33658934 |
| 28 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 1.31775359 |
| 29 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.30948126 |
| 30 | Alzheimers disease_Homo sapiens_hsa05010 | 1.30713673 |
| 31 | Peroxisome_Homo sapiens_hsa04146 | 1.30573638 |
| 32 | GABAergic synapse_Homo sapiens_hsa04727 | 1.26836501 |
| 33 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.24404604 |
| 34 | ABC transporters_Homo sapiens_hsa02010 | 1.14942176 |
| 35 | Retinol metabolism_Homo sapiens_hsa00830 | 1.13003430 |
| 36 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.12601939 |
| 37 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 1.12164573 |
| 38 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.11729261 |
| 39 | Dopaminergic synapse_Homo sapiens_hsa04728 | 1.10786532 |
| 40 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.10071900 |
| 41 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.09423351 |
| 42 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.07903759 |
| 43 | Taste transduction_Homo sapiens_hsa04742 | 1.05550224 |
| 44 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.05205011 |
| 45 | Insulin secretion_Homo sapiens_hsa04911 | 1.02459086 |
| 46 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.00461080 |
| 47 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.99767305 |
| 48 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 0.99441281 |
| 49 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.97744115 |
| 50 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.96582800 |
| 51 | Axon guidance_Homo sapiens_hsa04360 | 0.95386899 |
| 52 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 0.93741838 |
| 53 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.91349913 |
| 54 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.88311638 |
| 55 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.87356332 |
| 56 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.85885825 |
| 57 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.83744934 |
| 58 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.82788952 |
| 59 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.82108952 |
| 60 | Primary immunodeficiency_Homo sapiens_hsa05340 | 0.77024345 |
| 61 | Alcoholism_Homo sapiens_hsa05034 | 0.76161995 |
| 62 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.75278015 |
| 63 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.74746913 |
| 64 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.72944243 |
| 65 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.71992386 |
| 66 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.70201682 |
| 67 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.69824207 |
| 68 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.68562910 |
| 69 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.66306793 |
| 70 | RNA polymerase_Homo sapiens_hsa03020 | 0.66050579 |
| 71 | Metabolic pathways_Homo sapiens_hsa01100 | 0.65197609 |
| 72 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.64925867 |
| 73 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.64790093 |
| 74 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.64064170 |
| 75 | Circadian entrainment_Homo sapiens_hsa04713 | 0.60695670 |
| 76 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.60452607 |
| 77 | Cocaine addiction_Homo sapiens_hsa05030 | 0.59916274 |
| 78 | Synaptic vesicle cycle_Homo sapiens_hsa04721 | 0.57851165 |
| 79 | RNA degradation_Homo sapiens_hsa03018 | 0.54686272 |
| 80 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.54419509 |
| 81 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 0.53460588 |
| 82 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.53017158 |
| 83 | Basal cell carcinoma_Homo sapiens_hsa05217 | 0.51488760 |
| 84 | Basal transcription factors_Homo sapiens_hsa03022 | 0.51185922 |
| 85 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.50029482 |
| 86 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.48658683 |
| 87 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.46455131 |
| 88 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.44890133 |
| 89 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.43824951 |
| 90 | Bile secretion_Homo sapiens_hsa04976 | 0.40766781 |
| 91 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.39432269 |
| 92 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.39425163 |
| 93 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 0.36074447 |
| 94 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.34407617 |
| 95 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.31118166 |
| 96 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.28557345 |
| 97 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.28291690 |
| 98 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.28027426 |
| 99 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.27088089 |
| 100 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.25287428 |

