Rank | Gene Set | Z-score |
---|---|---|
1 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 8.78057595 |
2 | regulation of lipoprotein metabolic process (GO:0050746) | 8.73244117 |
3 | purine nucleotide transport (GO:0015865) | 8.72102327 |
4 | regulation of cytokine production involved in inflammatory response (GO:1900015) | 7.86616145 |
5 | regulation of platelet-derived growth factor receptor signaling pathway (GO:0010640) | 7.51968504 |
6 | short-chain fatty acid metabolic process (GO:0046459) | 7.51466737 |
7 | benzene-containing compound metabolic process (GO:0042537) | 7.44390668 |
8 | drinking behavior (GO:0042756) | 6.65623117 |
9 | negative regulation of adherens junction organization (GO:1903392) | 5.64344191 |
10 | negative regulation of focal adhesion assembly (GO:0051895) | 5.64344191 |
11 | negative regulation of cell junction assembly (GO:1901889) | 5.64344191 |
12 | negative regulation of chemokine production (GO:0032682) | 5.60652525 |
13 | positive regulation of chemokine secretion (GO:0090197) | 5.39440324 |
14 | nucleotide transport (GO:0006862) | 4.99747214 |
15 | primary alcohol catabolic process (GO:0034310) | 4.80383791 |
16 | regulation of chemokine secretion (GO:0090196) | 4.80124894 |
17 | positive regulation of glycolytic process (GO:0045821) | 4.64968039 |
18 | detection of chemical stimulus involved in sensory perception of bitter taste (GO:0001580) | 4.56766110 |
19 | negative regulation of leukocyte migration (GO:0002686) | 4.54684857 |
20 | regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358) | 4.35929428 |
21 | positive regulation of keratinocyte differentiation (GO:0045618) | 4.27208536 |
22 | axon regeneration (GO:0031103) | 4.09197580 |
23 | detection of chemical stimulus involved in sensory perception of taste (GO:0050912) | 3.96027490 |
24 | tryptophan catabolic process (GO:0006569) | 3.91930518 |
25 | indole-containing compound catabolic process (GO:0042436) | 3.91930518 |
26 | indolalkylamine catabolic process (GO:0046218) | 3.91930518 |
27 | positive regulation of action potential (GO:0045760) | 3.91269045 |
28 | piRNA metabolic process (GO:0034587) | 3.87409049 |
29 | tryptophan metabolic process (GO:0006568) | 3.84864087 |
30 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 3.80616083 |
31 | linoleic acid metabolic process (GO:0043651) | 3.76351951 |
32 | detection of light stimulus involved in visual perception (GO:0050908) | 3.74282405 |
33 | detection of light stimulus involved in sensory perception (GO:0050962) | 3.74282405 |
34 | retinal metabolic process (GO:0042574) | 3.72875710 |
35 | negative regulation of cell-matrix adhesion (GO:0001953) | 3.71716688 |
36 | kynurenine metabolic process (GO:0070189) | 3.67751458 |
37 | retina homeostasis (GO:0001895) | 3.63390589 |
38 | adhesion of symbiont to host cell (GO:0044650) | 3.56654150 |
39 | virion attachment to host cell (GO:0019062) | 3.56654150 |
40 | fucose catabolic process (GO:0019317) | 3.54945920 |
41 | L-fucose metabolic process (GO:0042354) | 3.54945920 |
42 | L-fucose catabolic process (GO:0042355) | 3.54945920 |
43 | regulation of phospholipid biosynthetic process (GO:0071071) | 3.48870859 |
44 | O-glycan processing (GO:0016266) | 3.46505896 |
45 | urinary tract smooth muscle contraction (GO:0014848) | 3.46130980 |
46 | ethanol metabolic process (GO:0006067) | 3.44246224 |
47 | regulation of keratinocyte differentiation (GO:0045616) | 3.37295253 |
48 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.34798102 |
49 | tachykinin receptor signaling pathway (GO:0007217) | 3.32924175 |
50 | positive regulation of macrophage derived foam cell differentiation (GO:0010744) | 3.31577239 |
51 | indolalkylamine metabolic process (GO:0006586) | 3.29379242 |
52 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.26510382 |
53 | cellular ketone body metabolic process (GO:0046950) | 3.25871941 |
54 | tyrosine metabolic process (GO:0006570) | 3.25856641 |
55 | aggressive behavior (GO:0002118) | 3.20124734 |
56 | regulation of T cell migration (GO:2000404) | 3.18969433 |
57 | aromatic amino acid family catabolic process (GO:0009074) | 3.17567878 |
58 | negative regulation of smooth muscle cell proliferation (GO:0048662) | 3.15807657 |
59 | regulation of Golgi to plasma membrane protein transport (GO:0042996) | 3.14537982 |
60 | cellular biogenic amine catabolic process (GO:0042402) | 3.13752267 |
61 | amine catabolic process (GO:0009310) | 3.13752267 |
62 | positive regulation of cellular amine metabolic process (GO:0033240) | 3.10387823 |
63 | axon development (GO:0061564) | 3.08958506 |
64 | long-chain fatty acid biosynthetic process (GO:0042759) | 3.04310050 |
65 | DNA methylation involved in gamete generation (GO:0043046) | 3.02632322 |
66 | regulation of action potential (GO:0098900) | 3.00424158 |
67 | ketone body metabolic process (GO:1902224) | 2.98843722 |
68 | regulation of T cell mediated cytotoxicity (GO:0001914) | 2.97140323 |
69 | biotin metabolic process (GO:0006768) | 2.96064665 |
70 | regulation of memory T cell differentiation (GO:0043380) | 2.96028003 |
71 | sphingomyelin metabolic process (GO:0006684) | 2.91941148 |
72 | regulation of hydrogen peroxide metabolic process (GO:0010310) | 2.87153884 |
73 | positive regulation of uterine smooth muscle contraction (GO:0070474) | 2.86657157 |
74 | positive regulation of epidermal cell differentiation (GO:0045606) | 2.86265260 |
75 | adhesion of symbiont to host (GO:0044406) | 2.85070826 |
76 | white fat cell differentiation (GO:0050872) | 2.84499745 |
77 | negative regulation of JUN kinase activity (GO:0043508) | 2.82497651 |
78 | Golgi to endosome transport (GO:0006895) | 2.78047636 |
79 | regulation of protein polyubiquitination (GO:1902914) | 2.69900577 |
80 | valine metabolic process (GO:0006573) | 2.68057791 |
81 | protein import into peroxisome matrix (GO:0016558) | 2.64543614 |
82 | neuron projection regeneration (GO:0031102) | 2.60963305 |
83 | lactate metabolic process (GO:0006089) | 2.59561543 |
84 | intestinal epithelial cell development (GO:0060576) | 2.58420918 |
85 | negative regulation of complement activation (GO:0045916) | 2.56183181 |
86 | protein O-linked glycosylation (GO:0006493) | 2.56080213 |
87 | tissue regeneration (GO:0042246) | 2.53395143 |
88 | regulation of insulin-like growth factor receptor signaling pathway (GO:0043567) | 2.53330813 |
89 | keratinocyte proliferation (GO:0043616) | 2.52866148 |
90 | positive regulation of vascular permeability (GO:0043117) | 2.52044789 |
91 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 2.51479186 |
92 | growth hormone receptor signaling pathway (GO:0060396) | 2.47765197 |
93 | aromatic amino acid family metabolic process (GO:0009072) | 2.45869349 |
94 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 2.45713129 |
95 | primary alcohol metabolic process (GO:0034308) | 2.44890623 |
96 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 2.42953375 |
97 | lung secretory cell differentiation (GO:0061140) | 2.41691345 |
98 | positive regulation of cholesterol transport (GO:0032376) | 2.39836179 |
99 | positive regulation of sterol transport (GO:0032373) | 2.39836179 |
100 | fatty acid biosynthetic process (GO:0006633) | 2.36982693 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 6.31711371 |
2 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 3.81944556 |
3 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 3.44162077 |
4 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 2.80112520 |
5 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 2.78036791 |
6 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 2.74328934 |
7 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.66269806 |
8 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 2.54338020 |
9 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 2.37087078 |
10 | VDR_22108803_ChIP-Seq_LS180_Human | 2.35504999 |
11 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 2.30148006 |
12 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.29346281 |
13 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.08910404 |
14 | AHR_22903824_ChIP-Seq_MCF-7_Human | 2.07056509 |
15 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.95382582 |
16 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 1.93259033 |
17 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.91854641 |
18 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 1.89594790 |
19 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.87237537 |
20 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.86061625 |
21 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.85475277 |
22 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.84293918 |
23 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.73723220 |
24 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 1.72402302 |
25 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.65721056 |
26 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.62096627 |
27 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.54853208 |
28 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.54545605 |
29 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.52987777 |
30 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.52906381 |
31 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.50235957 |
32 | CJUN_26792858_Chip-Seq_BT549_Human | 1.49869757 |
33 | RXR_22108803_ChIP-Seq_LS180_Human | 1.49175087 |
34 | ELF5_23300383_ChIP-Seq_T47D_Human | 1.48483884 |
35 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.45424990 |
36 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.45080813 |
37 | CDX2_22108803_ChIP-Seq_LS180_Human | 1.42959811 |
38 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.42924740 |
39 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 1.42538539 |
40 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 1.42334839 |
41 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.42172977 |
42 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.40865439 |
43 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.37049367 |
44 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.36929069 |
45 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.35999378 |
46 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.35030709 |
47 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.30011896 |
48 | AR_25329375_ChIP-Seq_VCAP_Human | 1.28100561 |
49 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.26012174 |
50 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.25956206 |
51 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.25750822 |
52 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 1.24248887 |
53 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 1.23996224 |
54 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.23614879 |
55 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 1.20459556 |
56 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.20264487 |
57 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.19186084 |
58 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 1.17822744 |
59 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.17677048 |
60 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.17677048 |
61 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.16883536 |
62 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.16545383 |
63 | P300_19829295_ChIP-Seq_ESCs_Human | 1.14089431 |
64 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.13963826 |
65 | GATA3_26560356_Chip-Seq_TH2_Human | 1.13530830 |
66 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.13473003 |
67 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.13244902 |
68 | STAT3_23295773_ChIP-Seq_U87_Human | 1.12921230 |
69 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.12038003 |
70 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.11251350 |
71 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.11251350 |
72 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.09646922 |
73 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.09579135 |
74 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.09256758 |
75 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.08707916 |
76 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.06424522 |
77 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.03544213 |
78 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.03212629 |
79 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.03159746 |
80 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.03054533 |
81 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.02044977 |
82 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.01957663 |
83 | TCF4_23295773_ChIP-Seq_U87_Human | 1.01805296 |
84 | E2F1_18555785_Chip-Seq_ESCs_Mouse | 1.01466014 |
85 | SOX2_18555785_Chip-Seq_ESCs_Mouse | 1.00703905 |
86 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.00683930 |
87 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.00277935 |
88 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.99908321 |
89 | AR_20517297_ChIP-Seq_VCAP_Human | 0.99691053 |
90 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.99638489 |
91 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 0.99062028 |
92 | ETV1_20927104_ChIP-Seq_GIST48_Human | 0.98983338 |
93 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.98818177 |
94 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 0.98245489 |
95 | TBL1_22424771_ChIP-Seq_293T_Human | 0.98017726 |
96 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 0.97994789 |
97 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.97946936 |
98 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 0.95528978 |
99 | SUZ12_18555785_Chip-Seq_ESCs_Mouse | 0.95169758 |
100 | PCGF4_22325352_ChIP-Seq_293T-Rex_Human | 0.93731128 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003183_abnormal_peptide_metabolism | 6.98363777 |
2 | MP0002166_altered_tumor_susceptibility | 3.69504426 |
3 | MP0009780_abnormal_chondrocyte_physiolo | 3.52979662 |
4 | MP0002009_preneoplasia | 3.50972997 |
5 | MP0003191_abnormal_cellular_cholesterol | 3.22624288 |
6 | MP0003941_abnormal_skin_development | 3.09955982 |
7 | MP0005310_abnormal_salivary_gland | 2.93899598 |
8 | MP0003195_calcinosis | 2.82431407 |
9 | MP0002006_tumorigenesis | 2.52417443 |
10 | MP0008995_early_reproductive_senescence | 2.49146474 |
11 | MP0001501_abnormal_sleep_pattern | 2.35533330 |
12 | MP0003724_increased_susceptibility_to | 2.33228478 |
13 | MP0010386_abnormal_urinary_bladder | 2.27492387 |
14 | MP0002876_abnormal_thyroid_physiology | 2.18907855 |
15 | MP0004264_abnormal_extraembryonic_tissu | 2.16305316 |
16 | MP0000372_irregular_coat_pigmentation | 2.07424262 |
17 | MP0001502_abnormal_circadian_rhythm | 2.05698436 |
18 | MP0008872_abnormal_physiological_respon | 1.97298632 |
19 | MP0004782_abnormal_surfactant_physiolog | 1.95964736 |
20 | MP0002938_white_spotting | 1.84377147 |
21 | MP0005670_abnormal_white_adipose | 1.77112004 |
22 | MP0005647_abnormal_sex_gland | 1.75469467 |
23 | MP0008875_abnormal_xenobiotic_pharmacok | 1.74930618 |
24 | MP0002736_abnormal_nociception_after | 1.73518247 |
25 | MP0006276_abnormal_autonomic_nervous | 1.71703648 |
26 | MP0010329_abnormal_lipoprotein_level | 1.63865431 |
27 | MP0005085_abnormal_gallbladder_physiolo | 1.56825253 |
28 | MP0005551_abnormal_eye_electrophysiolog | 1.47832393 |
29 | MP0002909_abnormal_adrenal_gland | 1.44455154 |
30 | MP0003252_abnormal_bile_duct | 1.43679591 |
31 | MP0005365_abnormal_bile_salt | 1.41302764 |
32 | MP0002796_impaired_skin_barrier | 1.40256078 |
33 | MP0002277_abnormal_respiratory_mucosa | 1.39449599 |
34 | MP0001727_abnormal_embryo_implantation | 1.37881667 |
35 | MP0004043_abnormal_pH_regulation | 1.36033816 |
36 | MP0005646_abnormal_pituitary_gland | 1.34846328 |
37 | MP0001968_abnormal_touch/_nociception | 1.32642581 |
38 | MP0000627_abnormal_mammary_gland | 1.31301028 |
39 | MP0000537_abnormal_urethra_morphology | 1.29103144 |
40 | MP0008877_abnormal_DNA_methylation | 1.28243198 |
41 | MP0002282_abnormal_trachea_morphology | 1.25497996 |
42 | MP0005408_hypopigmentation | 1.23264933 |
43 | MP0001919_abnormal_reproductive_system | 1.22776580 |
44 | MP0001485_abnormal_pinna_reflex | 1.20928513 |
45 | MP0000613_abnormal_salivary_gland | 1.18798793 |
46 | MP0003868_abnormal_feces_composition | 1.18685176 |
47 | MP0005083_abnormal_biliary_tract | 1.17630079 |
48 | MP0001881_abnormal_mammary_gland | 1.15047478 |
49 | MP0008961_abnormal_basal_metabolism | 1.14678336 |
50 | MP0006138_congestive_heart_failure | 1.13507844 |
51 | MP0002735_abnormal_chemical_nociception | 1.12594859 |
52 | MP0005503_abnormal_tendon_morphology | 1.08324845 |
53 | MP0009697_abnormal_copulation | 1.06198328 |
54 | MP0001529_abnormal_vocalization | 1.05352151 |
55 | MP0000427_abnormal_hair_cycle | 1.05250237 |
56 | MP0000383_abnormal_hair_follicle | 1.03161556 |
57 | MP0001661_extended_life_span | 1.01839962 |
58 | MP0004036_abnormal_muscle_relaxation | 1.01503167 |
59 | MP0001756_abnormal_urination | 0.99856725 |
60 | MP0002653_abnormal_ependyma_morphology | 0.99775553 |
61 | MP0002160_abnormal_reproductive_system | 0.98425350 |
62 | MP0002102_abnormal_ear_morphology | 0.96842527 |
63 | MP0002098_abnormal_vibrissa_morphology | 0.96623730 |
64 | MP0003315_abnormal_perineum_morphology | 0.96618622 |
65 | MP0004085_abnormal_heartbeat | 0.95947850 |
66 | MP0004084_abnormal_cardiac_muscle | 0.91653635 |
67 | MP0001666_abnormal_nutrient_absorption | 0.89037924 |
68 | MP0001873_stomach_inflammation | 0.87402416 |
69 | MP0009643_abnormal_urine_homeostasis | 0.86344530 |
70 | MP0002254_reproductive_system_inflammat | 0.85016326 |
71 | MP0003950_abnormal_plasma_membrane | 0.84089582 |
72 | MP0000230_abnormal_systemic_arterial | 0.83461119 |
73 | MP0002751_abnormal_autonomic_nervous | 0.82930692 |
74 | MP0003936_abnormal_reproductive_system | 0.82322826 |
75 | MP0000538_abnormal_urinary_bladder | 0.80901332 |
76 | MP0004381_abnormal_hair_follicle | 0.80782156 |
77 | MP0004019_abnormal_vitamin_homeostasis | 0.80421175 |
78 | MP0006072_abnormal_retinal_apoptosis | 0.79996874 |
79 | MP0005389_reproductive_system_phenotype | 0.79806110 |
80 | MP0004885_abnormal_endolymph | 0.79101933 |
81 | MP0002118_abnormal_lipid_homeostasis | 0.77588402 |
82 | MP0002557_abnormal_social/conspecific_i | 0.76661538 |
83 | MP0005275_abnormal_skin_tensile | 0.75450606 |
84 | MP0003011_delayed_dark_adaptation | 0.73776917 |
85 | MP0002933_joint_inflammation | 0.72548634 |
86 | MP0003638_abnormal_response/metabolism_ | 0.70718145 |
87 | MP0004742_abnormal_vestibular_system | 0.68935861 |
88 | MP0005410_abnormal_fertilization | 0.65216313 |
89 | MP0000163_abnormal_cartilage_morphology | 0.64512036 |
90 | MP0001765_abnormal_ion_homeostasis | 0.63659193 |
91 | MP0005535_abnormal_body_temperature | 0.63144555 |
92 | MP0002108_abnormal_muscle_morphology | 0.62966620 |
93 | MP0003938_abnormal_ear_development | 0.60803447 |
94 | MP0005636_abnormal_mineral_homeostasis | 0.60417007 |
95 | MP0002168_other_aberrant_phenotype | 0.59246062 |
96 | MP0005075_abnormal_melanosome_morpholog | 0.58920183 |
97 | MP0003787_abnormal_imprinting | 0.58544651 |
98 | MP0000026_abnormal_inner_ear | 0.58122592 |
99 | MP0003646_muscle_fatigue | 0.57395251 |
100 | MP0002115_abnormal_skeleton_extremities | 0.56933806 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Breast carcinoma (HP:0003002) | 6.06575622 |
2 | Abnormality of the renal cortex (HP:0011035) | 4.17247816 |
3 | Tubular atrophy (HP:0000092) | 3.85276525 |
4 | Gonadotropin excess (HP:0000837) | 3.54694205 |
5 | Pancreatic cysts (HP:0001737) | 3.47725393 |
6 | Concave nail (HP:0001598) | 3.45889708 |
7 | Spontaneous abortion (HP:0005268) | 3.45379292 |
8 | Progressive inability to walk (HP:0002505) | 3.37264309 |
9 | Tubulointerstitial nephritis (HP:0001970) | 3.26681388 |
10 | Azoospermia (HP:0000027) | 3.14099053 |
11 | Lip pit (HP:0100267) | 3.05602226 |
12 | Prostate neoplasm (HP:0100787) | 3.04315909 |
13 | Testicular atrophy (HP:0000029) | 3.01470688 |
14 | Hyperglycinuria (HP:0003108) | 3.00288019 |
15 | Pancreatic fibrosis (HP:0100732) | 3.00019843 |
16 | Renal cortical cysts (HP:0000803) | 2.97058200 |
17 | Abnormality of the renal medulla (HP:0100957) | 2.96499201 |
18 | Abnormality of the axillary hair (HP:0100134) | 2.96278685 |
19 | Abnormality of secondary sexual hair (HP:0009888) | 2.96278685 |
20 | Conjugated hyperbilirubinemia (HP:0002908) | 2.94804319 |
21 | Chronic sinusitis (HP:0011109) | 2.91231322 |
22 | Inability to walk (HP:0002540) | 2.90792021 |
23 | Widely patent fontanelles and sutures (HP:0004492) | 2.88489592 |
24 | Cystic liver disease (HP:0006706) | 2.84604738 |
25 | Congenital stationary night blindness (HP:0007642) | 2.82981794 |
26 | Pulmonary artery stenosis (HP:0004415) | 2.79630824 |
27 | Decreased circulating renin level (HP:0003351) | 2.73744132 |
28 | Hypothermia (HP:0002045) | 2.66105100 |
29 | Type II lissencephaly (HP:0007260) | 2.65388040 |
30 | Recurrent bronchitis (HP:0002837) | 2.64502058 |
31 | Increased corneal curvature (HP:0100692) | 2.60453092 |
32 | Keratoconus (HP:0000563) | 2.60453092 |
33 | Stomach cancer (HP:0012126) | 2.60443317 |
34 | Nephronophthisis (HP:0000090) | 2.58200164 |
35 | True hermaphroditism (HP:0010459) | 2.52108370 |
36 | Autoamputation (HP:0001218) | 2.50718439 |
37 | Abnormal spermatogenesis (HP:0008669) | 2.45090296 |
38 | Delayed CNS myelination (HP:0002188) | 2.42462837 |
39 | Molar tooth sign on MRI (HP:0002419) | 2.37468324 |
40 | Abnormality of midbrain morphology (HP:0002418) | 2.37468324 |
41 | Bile duct proliferation (HP:0001408) | 2.34357531 |
42 | Abnormal biliary tract physiology (HP:0012439) | 2.34357531 |
43 | Arthropathy (HP:0003040) | 2.32383881 |
44 | Gaze-evoked nystagmus (HP:0000640) | 2.27133072 |
45 | Right ventricular cardiomyopathy (HP:0011663) | 2.27115446 |
46 | Male pseudohermaphroditism (HP:0000037) | 2.26543911 |
47 | Glomerulonephritis (HP:0000099) | 2.23801679 |
48 | Posterior subcapsular cataract (HP:0007787) | 2.23775394 |
49 | Generalized hypopigmentation of hair (HP:0011358) | 2.23405610 |
50 | Bronchitis (HP:0012387) | 2.20912879 |
51 | Abnormality of nail color (HP:0100643) | 2.18275517 |
52 | Tubulointerstitial abnormality (HP:0001969) | 2.15358167 |
53 | Chronic hepatic failure (HP:0100626) | 2.15303858 |
54 | Tubulointerstitial fibrosis (HP:0005576) | 2.15230469 |
55 | Severe Myopia (HP:0011003) | 2.14192698 |
56 | Abnormality of serine family amino acid metabolism (HP:0010894) | 2.13527524 |
57 | Abnormality of glycine metabolism (HP:0010895) | 2.13527524 |
58 | Febrile seizures (HP:0002373) | 2.11790282 |
59 | Genetic anticipation (HP:0003743) | 2.07176049 |
60 | Abnormality of renal excretion (HP:0011036) | 2.07168517 |
61 | Attenuation of retinal blood vessels (HP:0007843) | 2.05008877 |
62 | Abnormality of the nasal septum (HP:0000419) | 2.04558438 |
63 | 3-Methylglutaconic aciduria (HP:0003535) | 2.02834752 |
64 | Vascular calcification (HP:0004934) | 2.02322302 |
65 | Medial flaring of the eyebrow (HP:0010747) | 2.01337312 |
66 | Abnormal cartilage morphology (HP:0002763) | 1.99729478 |
67 | Anhidrosis (HP:0000970) | 1.98133427 |
68 | Testicular neoplasm (HP:0010788) | 1.98050906 |
69 | Ectropion (HP:0000656) | 1.98044340 |
70 | Intrahepatic cholestasis (HP:0001406) | 1.96364523 |
71 | Amelogenesis imperfecta (HP:0000705) | 1.96331594 |
72 | Abnormal biliary tract morphology (HP:0012440) | 1.95511861 |
73 | Pendular nystagmus (HP:0012043) | 1.93698985 |
74 | Abnormality of the prostate (HP:0008775) | 1.92136166 |
75 | Cerebral palsy (HP:0100021) | 1.88954679 |
76 | Calf muscle hypertrophy (HP:0008981) | 1.88557046 |
77 | Aplasia cutis congenita (HP:0001057) | 1.88430810 |
78 | Arterial tortuosity (HP:0005116) | 1.88072336 |
79 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 1.87813639 |
80 | Abolished electroretinogram (ERG) (HP:0000550) | 1.87569362 |
81 | Aplasia/Hypoplasia of the tibia (HP:0005772) | 1.86961047 |
82 | Congenital hepatic fibrosis (HP:0002612) | 1.86118250 |
83 | Median cleft lip (HP:0000161) | 1.82457692 |
84 | Absent/shortened dynein arms (HP:0200106) | 1.80779355 |
85 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 1.80779355 |
86 | Reduced antithrombin III activity (HP:0001976) | 1.78878745 |
87 | Epiphyseal stippling (HP:0010655) | 1.78223847 |
88 | Abnormality of renin-angiotensin system (HP:0000847) | 1.77795158 |
89 | Ketoacidosis (HP:0001993) | 1.76597531 |
90 | Congenital, generalized hypertrichosis (HP:0004540) | 1.76207415 |
91 | Short hallux (HP:0010109) | 1.75090248 |
92 | Cone-rod dystrophy (HP:0000548) | 1.73371256 |
93 | Vascular tortuosity (HP:0004948) | 1.72684208 |
94 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.71008896 |
95 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.71008896 |
96 | Congenital ichthyosiform erythroderma (HP:0007431) | 1.70954513 |
97 | Adrenal hypoplasia (HP:0000835) | 1.69746267 |
98 | Barrel-shaped chest (HP:0001552) | 1.67584191 |
99 | Enlarged epiphyses (HP:0010580) | 1.67297303 |
100 | Broad nasal tip (HP:0000455) | 1.66968505 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BRSK2 | 6.27619562 |
2 | MST4 | 4.37614385 |
3 | FRK | 3.21726011 |
4 | EPHA2 | 2.89892997 |
5 | TNK2 | 2.73488918 |
6 | MAPKAPK3 | 2.38620777 |
7 | TRIM28 | 2.35055899 |
8 | STK39 | 2.26548710 |
9 | MST1R | 2.17411019 |
10 | WEE1 | 2.14413145 |
11 | BRSK1 | 1.95917300 |
12 | FER | 1.95270288 |
13 | STK38L | 1.94111145 |
14 | SIK3 | 1.82049349 |
15 | CAMKK2 | 1.76111797 |
16 | TAOK3 | 1.73721256 |
17 | GRK1 | 1.67975474 |
18 | EIF2AK3 | 1.65948769 |
19 | OXSR1 | 1.65054906 |
20 | CASK | 1.56786378 |
21 | WNK3 | 1.56667455 |
22 | MAP4K2 | 1.56445829 |
23 | PIK3CA | 1.56191845 |
24 | TLK1 | 1.56080379 |
25 | MATK | 1.54507897 |
26 | MAP3K7 | 1.51680366 |
27 | ERBB3 | 1.47954909 |
28 | SIK1 | 1.37731148 |
29 | ERBB2 | 1.36844306 |
30 | ADRBK2 | 1.36233317 |
31 | EIF2AK1 | 1.34239863 |
32 | NUAK1 | 1.32836260 |
33 | MAPK13 | 1.30445462 |
34 | ZAK | 1.25033787 |
35 | MET | 1.11291967 |
36 | SIK2 | 1.06905776 |
37 | TRPM7 | 1.05022959 |
38 | LATS1 | 1.03713938 |
39 | PRKAA2 | 0.99541417 |
40 | WNK4 | 0.98456258 |
41 | PIK3CG | 0.98397552 |
42 | MAPK15 | 0.97281776 |
43 | PINK1 | 0.94950429 |
44 | PAK3 | 0.91377095 |
45 | BMPR2 | 0.91333915 |
46 | BMPR1B | 0.88526562 |
47 | PRKAA1 | 0.84535239 |
48 | YES1 | 0.83127073 |
49 | PRKCE | 0.82465765 |
50 | CHUK | 0.76631751 |
51 | NTRK1 | 0.75776096 |
52 | PRKCI | 0.75308905 |
53 | IKBKB | 0.72396750 |
54 | PDGFRB | 0.62352707 |
55 | PHKG2 | 0.59884294 |
56 | PHKG1 | 0.59884294 |
57 | TNIK | 0.56966761 |
58 | IGF1R | 0.56462949 |
59 | EIF2AK2 | 0.53924610 |
60 | BCR | 0.51228594 |
61 | DYRK3 | 0.50676867 |
62 | MAP3K12 | 0.48204991 |
63 | ADRBK1 | 0.45270341 |
64 | NEK9 | 0.42632635 |
65 | IKBKE | 0.42386550 |
66 | INSRR | 0.42142955 |
67 | MAP3K4 | 0.41760055 |
68 | ABL1 | 0.39972268 |
69 | CSNK1A1 | 0.39780321 |
70 | STK3 | 0.38515121 |
71 | MKNK2 | 0.38482331 |
72 | PNCK | 0.37612679 |
73 | TEC | 0.36934037 |
74 | MAP2K7 | 0.35842832 |
75 | TIE1 | 0.35787710 |
76 | PRKCQ | 0.35004151 |
77 | CAMK1D | 0.34836865 |
78 | CSNK1E | 0.34037807 |
79 | KIT | 0.32976784 |
80 | PRKCG | 0.32464741 |
81 | MAP3K14 | 0.32398661 |
82 | NEK2 | 0.31971805 |
83 | CAMK1G | 0.31796443 |
84 | CAMKK1 | 0.29698084 |
85 | MUSK | 0.29646124 |
86 | RPS6KB1 | 0.28962664 |
87 | PRKCA | 0.27764733 |
88 | PLK4 | 0.27352520 |
89 | CDK3 | 0.26360678 |
90 | MAPKAPK5 | 0.25976529 |
91 | CAMK2D | 0.24030832 |
92 | FLT3 | 0.23948082 |
93 | CSNK1D | 0.21891438 |
94 | PTK2B | 0.21476190 |
95 | MAP2K2 | 0.20987319 |
96 | DYRK1A | 0.20207079 |
97 | MAPK8 | 0.20144327 |
98 | PRKACA | 0.19488584 |
99 | MARK3 | 0.17444613 |
100 | CAMK1 | 0.16443547 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Butanoate metabolism_Homo sapiens_hsa00650 | 4.94136103 |
2 | ABC transporters_Homo sapiens_hsa02010 | 3.71694536 |
3 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 3.10387569 |
4 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 2.84015671 |
5 | Histidine metabolism_Homo sapiens_hsa00340 | 2.76710864 |
6 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.69054636 |
7 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 2.43202496 |
8 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 2.40914464 |
9 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 2.36999712 |
10 | Circadian rhythm_Homo sapiens_hsa04710 | 2.26986816 |
11 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 2.22177357 |
12 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 2.11766442 |
13 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 2.10390413 |
14 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 1.99800270 |
15 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.98776691 |
16 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.85812064 |
17 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.82435644 |
18 | Retinol metabolism_Homo sapiens_hsa00830 | 1.81182475 |
19 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 1.76916574 |
20 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.71707751 |
21 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.67704335 |
22 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.66229148 |
23 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.63504775 |
24 | Peroxisome_Homo sapiens_hsa04146 | 1.57265558 |
25 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 1.48842584 |
26 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 1.41206661 |
27 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.38337592 |
28 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 1.34623029 |
29 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.33070180 |
30 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.31069216 |
31 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.29790539 |
32 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.29140234 |
33 | Renin secretion_Homo sapiens_hsa04924 | 1.27621167 |
34 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.23871409 |
35 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.18195039 |
36 | Phototransduction_Homo sapiens_hsa04744 | 1.17743671 |
37 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.15579142 |
38 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.13625732 |
39 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.10455621 |
40 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.07986532 |
41 | Tryptophan metabolism_Homo sapiens_hsa00380 | 1.01793414 |
42 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.99769065 |
43 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.98229916 |
44 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.96329899 |
45 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.96015051 |
46 | Pancreatic secretion_Homo sapiens_hsa04972 | 0.94529892 |
47 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.90269229 |
48 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 0.88898639 |
49 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.85950515 |
50 | Salivary secretion_Homo sapiens_hsa04970 | 0.85946322 |
51 | Mineral absorption_Homo sapiens_hsa04978 | 0.84048153 |
52 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.81588249 |
53 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.80700159 |
54 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 0.78647805 |
55 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.77921309 |
56 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.75501286 |
57 | Olfactory transduction_Homo sapiens_hsa04740 | 0.72323332 |
58 | Selenocompound metabolism_Homo sapiens_hsa00450 | 0.71555169 |
59 | Basal transcription factors_Homo sapiens_hsa03022 | 0.66235404 |
60 | Taste transduction_Homo sapiens_hsa04742 | 0.66092994 |
61 | Sulfur metabolism_Homo sapiens_hsa00920 | 0.65825482 |
62 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.64913892 |
63 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.58088311 |
64 | Protein export_Homo sapiens_hsa03060 | 0.54767922 |
65 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.48468871 |
66 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.48006302 |
67 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.47537250 |
68 | Insulin secretion_Homo sapiens_hsa04911 | 0.45860103 |
69 | RNA degradation_Homo sapiens_hsa03018 | 0.44401850 |
70 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.39236834 |
71 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 0.39117852 |
72 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.39006471 |
73 | Asthma_Homo sapiens_hsa05310 | 0.38621647 |
74 | Fat digestion and absorption_Homo sapiens_hsa04975 | 0.38057450 |
75 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.34732176 |
76 | Metabolic pathways_Homo sapiens_hsa01100 | 0.34082454 |
77 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.32563163 |
78 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.32232973 |
79 | Allograft rejection_Homo sapiens_hsa05330 | 0.31710218 |
80 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.30184328 |
81 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.29943520 |
82 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.29363612 |
83 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.29077518 |
84 | Homologous recombination_Homo sapiens_hsa03440 | 0.27703227 |
85 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.27306737 |
86 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.24862213 |
87 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.24741525 |
88 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.23654821 |
89 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.23209292 |
90 | Insulin resistance_Homo sapiens_hsa04931 | 0.22703916 |
91 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.20266388 |
92 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.19138786 |
93 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.18056847 |
94 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.17798492 |
95 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.17109617 |
96 | Amphetamine addiction_Homo sapiens_hsa05031 | 0.16157141 |
97 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.16040195 |
98 | Circadian entrainment_Homo sapiens_hsa04713 | 0.15803568 |
99 | RNA polymerase_Homo sapiens_hsa03020 | 0.15290689 |
100 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.14710480 |