CREBZF

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1nuclear pore organization (GO:0006999)5.31588871
2regulation of histone H3-K27 methylation (GO:0061085)5.31465610
3negative regulation of leukocyte mediated cytotoxicity (GO:0001911)4.36131839
4negative regulation of cell killing (GO:0031342)4.36131839
5DNA unwinding involved in DNA replication (GO:0006268)4.33708258
6positive regulation of histone deacetylation (GO:0031065)4.22569864
7pore complex assembly (GO:0046931)4.16330096
8regulation of NFAT protein import into nucleus (GO:0051532)4.10985318
9DNA topological change (GO:0006265)4.09365742
10regulation of chromatin binding (GO:0035561)3.84880739
11embryonic process involved in female pregnancy (GO:0060136)3.84627477
12cytoplasmic mRNA processing body assembly (GO:0033962)3.83553922
13mitotic chromosome condensation (GO:0007076)3.69959246
14embryonic camera-type eye morphogenesis (GO:0048596)3.64725350
15regulation of gamma-delta T cell differentiation (GO:0045586)3.51850603
16peptidyl-lysine dimethylation (GO:0018027)3.49385555
17negative regulation of mRNA splicing, via spliceosome (GO:0048025)3.46184605
18positive T cell selection (GO:0043368)3.45414360
19DNA duplex unwinding (GO:0032508)3.43327677
20histone H3-K4 trimethylation (GO:0080182)3.41953029
21definitive hemopoiesis (GO:0060216)3.40721696
22cytoskeletal anchoring at plasma membrane (GO:0007016)3.37218297
23monoubiquitinated protein deubiquitination (GO:0035520)3.34604326
24insulin-like growth factor receptor signaling pathway (GO:0048009)3.27869357
25positive thymic T cell selection (GO:0045059)3.27582361
26positive regulation of gamma-delta T cell activation (GO:0046645)3.27509783
27DNA geometric change (GO:0032392)3.26851171
28establishment of nucleus localization (GO:0040023)3.23313977
29protein localization to endosome (GO:0036010)3.23269089
30negative regulation of erythrocyte differentiation (GO:0045647)3.21688931
31dosage compensation (GO:0007549)3.19339446
32negative regulation of histone methylation (GO:0031061)3.19186235
333-UTR-mediated mRNA stabilization (GO:0070935)3.07640442
34locomotory exploration behavior (GO:0035641)3.04046621
35regulation of mRNA stability (GO:0043488)3.01027412
36establishment of protein localization to Golgi (GO:0072600)3.00456934
37regulation of gamma-delta T cell activation (GO:0046643)2.99501063
38layer formation in cerebral cortex (GO:0021819)2.99471513
39embryonic eye morphogenesis (GO:0048048)2.99102588
40response to epidermal growth factor (GO:0070849)2.97924909
41mRNA splice site selection (GO:0006376)2.95445214
42cerebellar Purkinje cell differentiation (GO:0021702)2.93943511
43nerve growth factor signaling pathway (GO:0038180)2.93749116
44cellular response to epidermal growth factor stimulus (GO:0071364)2.89579321
45regulation of RNA export from nucleus (GO:0046831)2.87834215
46spliceosomal tri-snRNP complex assembly (GO:0000244)2.87666010
47protein targeting to Golgi (GO:0000042)2.86626488
48positive regulation of cell cycle checkpoint (GO:1901978)2.85783748
49pre-miRNA processing (GO:0031054)2.85469932
50regulation of centriole replication (GO:0046599)2.84815543
51T cell selection (GO:0045058)2.82756035
52regulation of ARF GTPase activity (GO:0032312)2.82499406
53trophectodermal cell differentiation (GO:0001829)2.81620037
54regulation of DNA damage checkpoint (GO:2000001)2.81606275
55regulation of nucleobase-containing compound transport (GO:0032239)2.80800828
56phospholipid translocation (GO:0045332)2.80384059
57lipid translocation (GO:0034204)2.80384059
58negative regulation of DNA repair (GO:0045738)2.79170263
59thymic T cell selection (GO:0045061)2.77978732
60positive regulation of Rap GTPase activity (GO:0032854)2.77527922
61phosphatidylinositol-3-phosphate biosynthetic process (GO:0036092)2.77088994
62intracellular estrogen receptor signaling pathway (GO:0030520)2.76405201
63negative regulation of mRNA processing (GO:0050686)2.75952916
64retrograde transport, vesicle recycling within Golgi (GO:0000301)2.75785952
65stress granule assembly (GO:0034063)2.75640525
66regulation of Rap GTPase activity (GO:0032317)2.75440671
67regulation of RNA stability (GO:0043487)2.75211367
68protein export from nucleus (GO:0006611)2.75071635
69positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003602.74316127
70regulation of clathrin-mediated endocytosis (GO:2000369)2.73406444
71histone H3-K9 demethylation (GO:0033169)2.73306914
72protein demethylation (GO:0006482)2.71972472
73protein dealkylation (GO:0008214)2.71972472
74histone H3-K4 methylation (GO:0051568)2.71588264
75DNA conformation change (GO:0071103)2.70528231
76sister chromatid segregation (GO:0000819)2.70120605
77regulation of glucose import in response to insulin stimulus (GO:2001273)2.70000533
78peptidyl-lysine trimethylation (GO:0018023)2.69976176
79negative regulation of mRNA metabolic process (GO:1903312)2.67042482
80cortical actin cytoskeleton organization (GO:0030866)2.66929199
81DNA damage induced protein phosphorylation (GO:0006975)2.66473373
82peptidyl-lysine methylation (GO:0018022)2.66261364
83positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.65618664
84nucleus organization (GO:0006997)2.65373422
85negative T cell selection (GO:0043383)2.64286437
86sodium ion export (GO:0071436)2.63603143
87negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.61335755
88polyol transport (GO:0015791)2.59402953
89regulation of sister chromatid cohesion (GO:0007063)2.58592271
90regulation of ARF protein signal transduction (GO:0032012)2.57900631
91regulation of mitotic spindle organization (GO:0060236)2.55841609
92mitotic sister chromatid cohesion (GO:0007064)2.54703632
93peptidyl-threonine phosphorylation (GO:0018107)2.54525992
94histone H3-K36 demethylation (GO:0070544)2.53932711
95negative thymic T cell selection (GO:0045060)2.53812442
96peptidyl-threonine modification (GO:0018210)2.52080332
97histone H3-K9 methylation (GO:0051567)2.51268699
98nuclear-transcribed mRNA poly(A) tail shortening (GO:0000289)2.50940315
99histone deubiquitination (GO:0016578)2.50177341
100regulation of histone H3-K9 methylation (GO:0051570)2.50034719
101cellular potassium ion homeostasis (GO:0030007)2.49646049
102negative regulation of RNA splicing (GO:0033119)2.49407893
103poly(A)+ mRNA export from nucleus (GO:0016973)2.47721178
104regulation of centrosome duplication (GO:0010824)2.46819955
105positive regulation of protein deacetylation (GO:0090312)2.46415300
106negative regulation of histone modification (GO:0031057)2.43492122
107histone lysine demethylation (GO:0070076)2.42647149
108histone H4-K8 acetylation (GO:0043982)2.42227657
109histone H4-K5 acetylation (GO:0043981)2.42227657
110protein-DNA complex disassembly (GO:0032986)2.42187874
111nucleosome disassembly (GO:0006337)2.42187874
112glucocorticoid receptor signaling pathway (GO:0042921)2.41509103
113snRNA transcription (GO:0009301)2.40800682
114L-serine transport (GO:0015825)2.38576984
115regulation of epithelial cell proliferation involved in prostate gland development (GO:0060768)2.37942115
116regulation of Golgi to plasma membrane protein transport (GO:0042996)2.37222812
117negative regulation of translation, ncRNA-mediated (GO:0040033)2.34653926
118regulation of translation, ncRNA-mediated (GO:0045974)2.34653926
119negative regulation of translation involved in gene silencing by miRNA (GO:0035278)2.34653926
120mRNA transport (GO:0051028)2.34641512
121regulation of translational fidelity (GO:0006450)2.34591411
122epithelial cell differentiation involved in prostate gland development (GO:0060742)2.34520395
123interkinetic nuclear migration (GO:0022027)2.34329306
124regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.34284202
125nuclear pore complex assembly (GO:0051292)2.34013125
126paraxial mesoderm development (GO:0048339)2.33533381
127DNA synthesis involved in DNA repair (GO:0000731)2.32532722
128cortical cytoskeleton organization (GO:0030865)2.31824089
129alternative mRNA splicing, via spliceosome (GO:0000380)2.31246314
130activation of JUN kinase activity (GO:0007257)2.29887664
131regulation of cholesterol homeostasis (GO:2000188)2.29401570
132histone lysine methylation (GO:0034968)2.27695184
133adherens junction assembly (GO:0034333)2.27384694
134signal complex assembly (GO:0007172)2.25424879
135positive regulation of transcription from RNA polymerase III promoter (GO:0045945)2.23821809
136regulation of histone deacetylation (GO:0031063)2.21718319
137histone H3-K9 modification (GO:0061647)2.21238364
138growth hormone receptor signaling pathway (GO:0060396)2.21215340
139phosphatidylinositol dephosphorylation (GO:0046856)2.19117094
140histone demethylation (GO:0016577)2.18682475
141corticosteroid receptor signaling pathway (GO:0031958)2.18193521
142histone H4-K16 acetylation (GO:0043984)2.18063810
143serine transport (GO:0032329)2.15935214
144regulation of short-term neuronal synaptic plasticity (GO:0048172)2.15085399
145dendrite morphogenesis (GO:0048813)2.14195331
146germ cell migration (GO:0008354)2.12118043
147regulation of histone methylation (GO:0031060)2.11350860
148positive regulation of excitatory postsynaptic membrane potential (GO:2000463)2.11133965
149RNA stabilization (GO:0043489)2.11125416
150mRNA stabilization (GO:0048255)2.11125416
151phospholipid dephosphorylation (GO:0046839)2.10583259
152dendritic spine morphogenesis (GO:0060997)2.10434187
153regulation of histone H3-K4 methylation (GO:0051569)2.09731667
154regulation of Rac protein signal transduction (GO:0035020)2.09686591
155T cell receptor signaling pathway (GO:0050852)2.09362227
156negative regulation of GTP catabolic process (GO:0033125)2.09025021
157negative regulation of GTPase activity (GO:0034260)2.09025021
158cell-substrate adherens junction assembly (GO:0007045)2.08700999
159focal adhesion assembly (GO:0048041)2.08700999
160positive regulation of intracellular steroid hormone receptor signaling pathway (GO:0033145)2.07001378
161potassium ion import (GO:0010107)2.06654708
162positive regulation of RNA splicing (GO:0033120)2.06305184
163receptor catabolic process (GO:0032801)2.05595170
164activated T cell proliferation (GO:0050798)2.04575382
165regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition 2.01818440
166dicarboxylic acid biosynthetic process (GO:0043650)2.01165268

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human6.87120544
2FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse4.88208050
3RBPJ_22232070_ChIP-Seq_NCS_Mouse3.51563014
4NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse3.26433766
5FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.15386507
6MYC_22102868_ChIP-Seq_BL_Human3.02299184
7* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.89004982
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.64165061
9KDM2B_26808549_Chip-Seq_DND41_Human2.62331633
10KDM2B_26808549_Chip-Seq_HPB-ALL_Human2.54086117
11* TCF7_22412390_ChIP-Seq_EML_Mouse2.47958093
12KDM2B_26808549_Chip-Seq_SUP-B15_Human2.41307653
13E2F4_17652178_ChIP-ChIP_JURKAT_Human2.39913322
14* KDM2B_26808549_Chip-Seq_SIL-ALL_Human2.29716817
15EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse2.24819732
16TCF3_18467660_ChIP-ChIP_MESCs_Mouse2.21933474
17TP63_19390658_ChIP-ChIP_HaCaT_Human2.18841383
18* KDM2B_26808549_Chip-Seq_JURKAT_Human2.16649519
19STAT6_21828071_ChIP-Seq_BEAS2B_Human2.10207386
20CIITA_25753668_ChIP-Seq_RAJI_Human2.09403160
21ZFP322A_24550733_ChIP-Seq_MESCs_Mouse2.05793586
22E2F1_21310950_ChIP-Seq_MCF-7_Human2.04566346
23VDR_21846776_ChIP-Seq_THP-1_Human2.03694799
24ASXL1_24218140_ChIP-Seq_BMDM_Mouse2.01278231
25WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.99927243
26RUNX_20019798_ChIP-Seq_JUKART_Human1.96584091
27ZFP281_27345836_Chip-Seq_ESCs_Mouse1.94200334
28KDM2B_26808549_Chip-Seq_K562_Human1.90838751
29* DMRT1_23473982_ChIP-Seq_TESTES_Mouse1.89788368
30BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.88435581
31FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.86098230
32TP53_16413492_ChIP-PET_HCT116_Human1.85374764
33VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.83911771
34PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.80921592
35RARB_27405468_Chip-Seq_BRAIN_Mouse1.80610014
36AR_21909140_ChIP-Seq_LNCAP_Human1.79551046
37ESR1_15608294_ChIP-ChIP_MCF-7_Human1.79244975
38MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.75278653
39EGR1_19374776_ChIP-ChIP_THP-1_Human1.69856294
40DROSHA_22980978_ChIP-Seq_HELA_Human1.62055202
41ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.57106475
42FOXM1_23109430_ChIP-Seq_U2OS_Human1.56805643
43UTX_26944678_Chip-Seq_JUKART_Human1.55552176
44GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.54759373
45P300_27058665_Chip-Seq_ZR-75-30cells_Human1.50547791
46FOXO3_23340844_ChIP-Seq_DLD1_Human1.49815565
47SALL1_21062744_ChIP-ChIP_HESCs_Human1.48755916
48FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.48552739
49FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.47307965
50MAF_26560356_Chip-Seq_TH1_Human1.46519877
51WT1_19549856_ChIP-ChIP_CCG9911_Human1.45818216
52TFAP2C_20629094_ChIP-Seq_MCF-7_Human1.45321515
53SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.42844262
54* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.40830012
55* CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse1.39273848
56EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.36967669
57SCL_19346495_ChIP-Seq_HPC-7_Human1.35824155
58ZNF217_24962896_ChIP-Seq_MCF-7_Human1.35043238
59TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.34624569
60STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.34258248
61* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.32472917
62STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.31795812
63* KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.29708651
64TP63_17297297_ChIP-ChIP_HaCaT_Human1.29612323
65ESR1_20079471_ChIP-ChIP_T-47D_Human1.29169573
66E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.28417874
67YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.28360981
68GATA1_19941826_ChIP-Seq_K562_Human1.27865841
69ZFP281_18757296_ChIP-ChIP_E14_Mouse1.26300612
70ZNF263_19887448_ChIP-Seq_K562_Human1.25999859
71SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.25849887
72VDR_24763502_ChIP-Seq_THP-1_Human1.25007771
73EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human1.24951847
74* DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.24775410
75CREB1_26743006_Chip-Seq_LNCaP_Human1.24446197
76PKCTHETA_26484144_Chip-Seq_BREAST_Human1.23699310
77CLOCK_20551151_ChIP-Seq_293T_Human1.23214392
78* ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.22006578
79NFIB_24661679_ChIP-Seq_LUNG_Mouse1.21923090
80* FOXA2_19822575_ChIP-Seq_HepG2_Human1.21845923
81WT1_25993318_ChIP-Seq_PODOCYTE_Human1.21314921
82AR_21572438_ChIP-Seq_LNCaP_Human1.19618321
83CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.16671153
84* CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.15571482
85* MYB_26560356_Chip-Seq_TH1_Human1.15066322
86* ELK3_25401928_ChIP-Seq_HUVEC_Human1.13374619
87NANOG_21062744_ChIP-ChIP_HESCs_Human1.13093376
88KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.12391252
89* HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.12095841
90ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.10894054
91ISL1_27105846_Chip-Seq_CPCs_Mouse1.07410156
92TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.06794386
93AHR_22903824_ChIP-Seq_MCF-7_Human1.06123453
94SMAD3_22036565_ChIP-Seq_ESCs_Mouse1.05821911
95* MYB_26560356_Chip-Seq_TH2_Human1.05010587
96CTNNB1_20460455_ChIP-Seq_HCT116_Human1.04548988
97RUNX1_27514584_Chip-Seq_MCF-7_Human1.03998818
98DNAJC2_21179169_ChIP-ChIP_NT2_Human1.03517137
99HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse1.03297421
100RUNX1_17652178_ChIP-ChIP_JURKAT_Human1.03259761
101MYCN_18555785_ChIP-Seq_MESCs_Mouse1.01464850
102GATA1_22025678_ChIP-Seq_K562_Human1.00606674
103ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.00536579
104MYC_18555785_ChIP-Seq_MESCs_Mouse1.00470801
105HIF1A_21447827_ChIP-Seq_MCF-7_Human0.99207688
106ARNT_22903824_ChIP-Seq_MCF-7_Human0.98990047
107ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.98618260
108RXR_22108803_ChIP-Seq_LS180_Human0.97638723
109* NCOR1_26117541_ChIP-Seq_K562_Human0.97065128
110SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.96414659
111POU5F1_18555785_ChIP-Seq_MESCs_Mouse0.96288646
112SALL4_18804426_ChIP-ChIP_XEN_Mouse0.95563335
113CHD1_26751641_Chip-Seq_LNCaP_Human0.94914882
114ESR2_21235772_ChIP-Seq_MCF-7_Human0.94758234
115KLF4_18555785_ChIP-Seq_MESCs_Mouse0.94607082
116NR1I2_20693526_ChIP-Seq_LIVER_Mouse0.94602027
117SMAD_19615063_ChIP-ChIP_OVARY_Human0.94539667
118KDM5A_27292631_Chip-Seq_BREAST_Human0.94078073
119EZH2_22144423_ChIP-Seq_EOC_Human0.93998028
120AR_19668381_ChIP-Seq_PC3_Human0.93502825
121BRD4_27068464_Chip-Seq_AML-cells_Mouse0.92934423
122YAP1_20516196_ChIP-Seq_MESCs_Mouse0.92729919
123LXR_22292898_ChIP-Seq_THP-1_Human0.92493048
124CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons0.91394719
125MYC_19079543_ChIP-ChIP_MESCs_Mouse0.91196978
126RACK7_27058665_Chip-Seq_MCF-7_Human0.90743820
127RING1B_27294783_Chip-Seq_NPCs_Mouse0.90233892
128GATA3_27048872_Chip-Seq_THYMUS_Human0.89963805
129KLF2_18264089_ChIP-ChIP_MESCs_Mouse0.89661691
130KLF5_18264089_ChIP-ChIP_MESCs_Mouse0.89661691
131KLF4_18264089_ChIP-ChIP_MESCs_Mouse0.89661691
132MTF2_20144788_ChIP-Seq_MESCs_Mouse0.89269259
133TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.88995793
134ZNF274_21170338_ChIP-Seq_K562_Hela0.88794953
135SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse0.88477592
136SMAD1_18555785_ChIP-Seq_MESCs_Mouse0.88376562
137SOX2_27498859_Chip-Seq_STOMACH_Mouse0.88315392
138CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat0.88273296
139SPI1_23127762_ChIP-Seq_K562_Human0.86243764
140JARID2_20064375_ChIP-Seq_MESCs_Mouse0.86148060
141EZH2_18974828_ChIP-Seq_MESCs_Mouse0.85396275
142RNF2_18974828_ChIP-Seq_MESCs_Mouse0.85396275
143SOX9_24532713_ChIP-Seq_HFSC_Mouse0.85182904
144SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.83914673
145MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.82134291

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008057_abnormal_DNA_replication4.94307419
2MP0010234_abnormal_vibrissa_follicle3.90953098
3MP0004859_abnormal_synaptic_plasticity3.69008495
4MP0003300_gastrointestinal_ulcer3.66845681
5MP0003705_abnormal_hypodermis_morpholog2.78273118
6MP0002166_altered_tumor_susceptibility2.46009421
7MP0003787_abnormal_imprinting2.44453933
8MP0010094_abnormal_chromosome_stability2.42140743
9MP0005076_abnormal_cell_differentiation2.41686961
10MP0008961_abnormal_basal_metabolism2.29998230
11MP0009780_abnormal_chondrocyte_physiolo2.28266279
12MP0003303_peritoneal_inflammation2.19635524
13MP0002009_preneoplasia2.19581730
14MP0004885_abnormal_endolymph2.17425881
15MP0003111_abnormal_nucleus_morphology2.17306806
16MP0000569_abnormal_digit_pigmentation2.15923527
17MP0003077_abnormal_cell_cycle2.07781861
18MP0000566_synostosis2.04751551
19MP0004185_abnormal_adipocyte_glucose1.99901869
20MP0004264_abnormal_extraembryonic_tissu1.93204946
21MP0005623_abnormal_meninges_morphology1.89549513
22MP0010678_abnormal_skin_adnexa1.86952145
23MP0003045_fibrosis1.85483790
24MP0003252_abnormal_bile_duct1.75853740
25MP0003890_abnormal_embryonic-extraembry1.75242659
26MP0003635_abnormal_synaptic_transmissio1.71254229
27MP0010352_gastrointestinal_tract_polyps1.71196167
28MP0001730_embryonic_growth_arrest1.67364940
29MP0001346_abnormal_lacrimal_gland1.67064424
30MP0003763_abnormal_thymus_physiology1.66461482
31MP0000350_abnormal_cell_proliferation1.65991246
32MP0009278_abnormal_bone_marrow1.65823459
33MP0000733_abnormal_muscle_development1.64109446
34MP0003984_embryonic_growth_retardation1.57135165
35MP0002006_tumorigenesis1.52451028
36MP0000003_abnormal_adipose_tissue1.51564691
37MP0001672_abnormal_embryogenesis/_devel1.50385006
38MP0005380_embryogenesis_phenotype1.50385006
39MP0002088_abnormal_embryonic_growth/wei1.50267960
40MP0005187_abnormal_penis_morphology1.45203288
41MP0008569_lethality_at_weaning1.44050125
42MP0004957_abnormal_blastocyst_morpholog1.39998688
43MP0002877_abnormal_melanocyte_morpholog1.39897494
44MP0003329_amyloid_beta_deposits1.34334092
45MP0000703_abnormal_thymus_morphology1.32791824
46MP0003283_abnormal_digestive_organ1.32750843
47MP0008770_decreased_survivor_rate1.32457075
48MP0003693_abnormal_embryo_hatching1.32129919
49MP0000920_abnormal_myelination1.29965985
50MP0005375_adipose_tissue_phenotype1.26395192
51MP0002928_abnormal_bile_duct1.25118815
52MP0005409_darkened_coat_color1.20296214
53MP0008007_abnormal_cellular_replicative1.19228547
54MP0004197_abnormal_fetal_growth/weight/1.17932979
55MP0003221_abnormal_cardiomyocyte_apopto1.17248576
56MP0001697_abnormal_embryo_size1.15347701
57MP0002249_abnormal_larynx_morphology1.15136117
58MP0002063_abnormal_learning/memory/cond1.14720965
59MP0009745_abnormal_behavioral_response1.14214483
60MP0001486_abnormal_startle_reflex1.13750969
61MP0003091_abnormal_cell_migration1.11987641
62MP0000537_abnormal_urethra_morphology1.11915082
63MP0005220_abnormal_exocrine_pancreas1.09614701
64MP0002080_prenatal_lethality1.08688181
65MP0000604_amyloidosis1.08463336
66MP0004808_abnormal_hematopoietic_stem1.07675882
67MP0002064_seizures1.07637465
68MP0009046_muscle_twitch1.07380377
69MP0004381_abnormal_hair_follicle1.05445311
70MP0002084_abnormal_developmental_patter1.05042116
71MP0010630_abnormal_cardiac_muscle1.03071897
72MP0000955_abnormal_spinal_cord1.02100495
73MP0003632_abnormal_nervous_system1.01224505
74MP0002398_abnormal_bone_marrow1.00840008
75MP0004270_analgesia1.00527168
76MP0002085_abnormal_embryonic_tissue1.00158138
77MP0003868_abnormal_feces_composition0.99992397
78MP0005666_abnormal_adipose_tissue0.99657947
79MP0005621_abnormal_cell_physiology0.99585747
80MP0000778_abnormal_nervous_system0.98830422
81MP0009703_decreased_birth_body0.98540210
82MP0003937_abnormal_limbs/digits/tail_de0.96928852
83MP0002396_abnormal_hematopoietic_system0.96093750
84MP0003633_abnormal_nervous_system0.95918074
85MP0000013_abnormal_adipose_tissue0.94972344
86MP0002098_abnormal_vibrissa_morphology0.94873805
87MP0002925_abnormal_cardiovascular_devel0.94623027
88MP0000383_abnormal_hair_follicle0.94220639
89MP0004742_abnormal_vestibular_system0.94122863
90MP0005360_urolithiasis0.93583711
91MP0004510_myositis0.92843794
92MP0006072_abnormal_retinal_apoptosis0.92838745
93MP0001800_abnormal_humoral_immune0.92447072
94MP0002086_abnormal_extraembryonic_tissu0.91613314
95MP0003453_abnormal_keratinocyte_physiol0.91339548
96MP0000685_abnormal_immune_system0.91249980
97MP0004130_abnormal_muscle_cell0.91155999
98MP0003866_abnormal_defecation0.90856688
99MP0002092_abnormal_eye_morphology0.90449468
100MP0003121_genomic_imprinting0.90358103
101MP0003115_abnormal_respiratory_system0.90350416
102MP0001340_abnormal_eyelid_morphology0.88142980
103MP0004782_abnormal_surfactant_physiolog0.88080559
104MP0002152_abnormal_brain_morphology0.87854653
105MP0004811_abnormal_neuron_physiology0.87039542
106MP0001784_abnormal_fluid_regulation0.86227352
107MP0008874_decreased_physiological_sensi0.85831836
108MP0006138_congestive_heart_failure0.85733659
109MP0003690_abnormal_glial_cell0.85196387
110MP0009672_abnormal_birth_weight0.83829642
111MP0001849_ear_inflammation0.83363697
112MP0003943_abnormal_hepatobiliary_system0.83361884
113MP0003861_abnormal_nervous_system0.82836405
114MP0000313_abnormal_cell_death0.82104066
115MP0003123_paternal_imprinting0.81175835
116MP0003631_nervous_system_phenotype0.80404062
117MP0001286_abnormal_eye_development0.79817153
118MP0002089_abnormal_postnatal_growth/wei0.79337557
119MP0008932_abnormal_embryonic_tissue0.78998475
120MP0001177_atelectasis0.78424625
121MP0002081_perinatal_lethality0.78328316
122MP0002139_abnormal_hepatobiliary_system0.76211128
123MP0001873_stomach_inflammation0.75309532
124MP0003942_abnormal_urinary_system0.75289600
125MP0000377_abnormal_hair_follicle0.75275913
126MP0002272_abnormal_nervous_system0.74841592
127MP0001348_abnormal_lacrimal_gland0.74806456
128MP0003880_abnormal_central_pattern0.74773579
129MP0005248_abnormal_Harderian_gland0.74570870
130MP0000432_abnormal_head_morphology0.74402919
131MP0000490_abnormal_crypts_of0.73907848
132MP0005423_abnormal_somatic_nervous0.72302994
133MP0000465_gastrointestinal_hemorrhage0.72213520
134MP0001915_intracranial_hemorrhage0.72099703
135MP0001851_eye_inflammation0.71616930
136MP0002697_abnormal_eye_size0.71199443
137MP0003935_abnormal_craniofacial_develop0.71088640
138MP0002114_abnormal_axial_skeleton0.70012149
139MP0001485_abnormal_pinna_reflex0.68843342
140MP0010307_abnormal_tumor_latency0.68774683
141MP0002572_abnormal_emotion/affect_behav0.67866268
142MP0000428_abnormal_craniofacial_morphol0.67689462
143MP0010769_abnormal_survival0.67657887
144MP0004947_skin_inflammation0.67287358
145MP0001270_distended_abdomen0.67181051
146MP0003656_abnormal_erythrocyte_physiolo0.66540663
147MP0000462_abnormal_digestive_system0.66314372
148MP0002722_abnormal_immune_system0.65478252
149MP0005501_abnormal_skin_physiology0.62728901
150MP0005384_cellular_phenotype0.62246463
151MP0002116_abnormal_craniofacial_bone0.62194940
152MP0003315_abnormal_perineum_morphology0.60682006

Predicted human phenotypes

RankGene SetZ-score
1Asymmetry of the thorax (HP:0001555)3.65484635
2Macroorchidism (HP:0000053)3.58657806
3Abnormality of the fingertips (HP:0001211)3.37402749
4Hyperacusis (HP:0010780)2.89937819
5Germ cell neoplasia (HP:0100728)2.75551747
6Papillary thyroid carcinoma (HP:0002895)2.75065760
7Vertebral arch anomaly (HP:0008438)2.72910522
8Heterotopia (HP:0002282)2.72793144
9Syringomyelia (HP:0003396)2.71943135
10Spinal cord lesions (HP:0100561)2.71943135
11Insidious onset (HP:0003587)2.67113666
12Termporal pattern (HP:0011008)2.67113666
13Cerebral aneurysm (HP:0004944)2.66404998
14Short 4th metacarpal (HP:0010044)2.61199607
15Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042)2.61199607
16Sandal gap (HP:0001852)2.53943840
17Abnormality of the distal phalanx of the thumb (HP:0009617)2.46187837
18Broad face (HP:0000283)2.44325899
19Insomnia (HP:0100785)2.42822113
20Viral hepatitis (HP:0006562)2.33207595
21Acute lymphatic leukemia (HP:0006721)2.29119176
22Hemiplegia (HP:0002301)2.25391104
23Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.24692676
24Elfin facies (HP:0004428)2.20711162
25Broad palm (HP:0001169)2.20623810
26Overlapping toe (HP:0001845)2.19870686
27Flat acetabular roof (HP:0003180)2.19464886
28Volvulus (HP:0002580)2.18798060
29Abnormality of oral frenula (HP:0000190)2.18791764
30Missing ribs (HP:0000921)2.18028702
31Acute myeloid leukemia (HP:0004808)2.17776723
3211 pairs of ribs (HP:0000878)2.13790321
33Ulnar bowing (HP:0003031)2.13363298
34Renovascular hypertension (HP:0100817)2.12167526
35T lymphocytopenia (HP:0005403)2.12162473
36Narrow palate (HP:0000189)2.09972938
37Obsessive-compulsive behavior (HP:0000722)2.09397189
38Dysmetric saccades (HP:0000641)2.07899730
39Shallow orbits (HP:0000586)2.07554419
40Pseudobulbar signs (HP:0002200)2.07538512
41Neoplasm of the heart (HP:0100544)2.07187089
42Subacute progressive viral hepatitis (HP:0006572)2.06650551
43Atrophy/Degeneration involving the corticospinal tracts (HP:0007372)2.05340517
44Degeneration of the lateral corticospinal tracts (HP:0002314)2.05340517
45Dislocated radial head (HP:0003083)2.04080340
46Abnormality of the 4th metacarpal (HP:0010012)2.02918397
47Bronchomalacia (HP:0002780)2.00857050
48Aqueductal stenosis (HP:0002410)2.00587730
49Abnormality of the lower motor neuron (HP:0002366)2.00512677
50Ankyloglossia (HP:0010296)1.99820654
51Mitral valve prolapse (HP:0001634)1.98886924
52Overriding aorta (HP:0002623)1.97249183
53Abnormality of the corticospinal tract (HP:0002492)1.95931656
54Obstructive sleep apnea (HP:0002870)1.95265746
55Truncal obesity (HP:0001956)1.95212504
56Increased density of long bones (HP:0006392)1.94396250
57Increased nuchal translucency (HP:0010880)1.94278854
58Pointed chin (HP:0000307)1.92923564
59Sparse lateral eyebrow (HP:0005338)1.92593475
60Absent frontal sinuses (HP:0002688)1.92567038
61Verrucae (HP:0200043)1.91699530
62Papilloma (HP:0012740)1.91699530
63Abnormality of the radial head (HP:0003995)1.90556365
64Leiomyosarcoma (HP:0100243)1.90509220
65Uterine leiomyosarcoma (HP:0002891)1.90509220
66Hepatoblastoma (HP:0002884)1.90302108
67Abnormality of chromosome segregation (HP:0002916)1.89953669
68Metaphyseal cupping (HP:0003021)1.89882317
69Deep philtrum (HP:0002002)1.89745973
70Abnormality of the calcaneus (HP:0008364)1.89420222
71Bladder neoplasm (HP:0009725)1.88967747
72Bladder carcinoma (HP:0002862)1.88967747
73Supernumerary ribs (HP:0005815)1.88709768
74Urinary urgency (HP:0000012)1.88072827
75Arnold-Chiari malformation (HP:0002308)1.87694456
76Buphthalmos (HP:0000557)1.85956144
77Gastrointestinal carcinoma (HP:0002672)1.84941506
78Malignant gastrointestinal tract tumors (HP:0006749)1.84941506
79Truncal ataxia (HP:0002078)1.84828452
80Subaortic stenosis (HP:0001682)1.84518262
81Abnormality of the left ventricular outflow tract (HP:0011103)1.84518262
82Abnormality of T cell number (HP:0011839)1.83729853
83High anterior hairline (HP:0009890)1.83364644
84Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.82406546
85Spastic diplegia (HP:0001264)1.82194701
86Scanning speech (HP:0002168)1.81463243
87Hereditary nonpolyposis colorectal carcinoma (HP:0006716)1.81071662
88Long eyelashes (HP:0000527)1.80512452
89Impaired vibration sensation in the lower limbs (HP:0002166)1.79918630
90Nephroblastoma (Wilms tumor) (HP:0002667)1.79775079
91Persistence of primary teeth (HP:0006335)1.79351914
92Intention tremor (HP:0002080)1.79014722
93Deep venous thrombosis (HP:0002625)1.77768457
94Cubitus valgus (HP:0002967)1.77102688
95Biconcave vertebral bodies (HP:0004586)1.76842532
96Septate vagina (HP:0001153)1.76751099
97Basal cell carcinoma (HP:0002671)1.76584914
98Anal stenosis (HP:0002025)1.76421524
99Colitis (HP:0002583)1.74965124
100Embryonal neoplasm (HP:0002898)1.74875834
101Cutis marmorata (HP:0000965)1.74813519
102Abnormality of the parietal bone (HP:0002696)1.74398051
103Low anterior hairline (HP:0000294)1.72002140
104Hematochezia (HP:0002573)1.71920497
105Medulloblastoma (HP:0002885)1.71708059
106Action tremor (HP:0002345)1.71280070
107Bowel diverticulosis (HP:0005222)1.71128941
108Neonatal hypoglycemia (HP:0001998)1.70981678
109Aortic aneurysm (HP:0004942)1.70848680
110Impaired smooth pursuit (HP:0007772)1.70525883
111Hypopigmentation of the fundus (HP:0007894)1.69231661
112Menstrual irregularities (HP:0000858)1.69195186
113Thick eyebrow (HP:0000574)1.69139153
114Turricephaly (HP:0000262)1.68516711
115Supranuclear gaze palsy (HP:0000605)1.67825861
116Neoplasm of the oral cavity (HP:0100649)1.67424437
117Thyroid carcinoma (HP:0002890)1.66787971
118Lower limb asymmetry (HP:0100559)1.66336454
119Resting tremor (HP:0002322)1.66123915
120Anteriorly placed anus (HP:0001545)1.64400154
121Cafe-au-lait spot (HP:0000957)1.63989100
122Cerebral inclusion bodies (HP:0100314)1.63938362
123Curly hair (HP:0002212)1.62934851
124Abnormality of the diencephalon (HP:0010662)1.62882706
125Spastic gait (HP:0002064)1.62745059
126Fibrous tissue neoplasm (HP:0012316)1.62641844
127Abnormal foot bone ossification (HP:0010675)1.62175057
128Aneurysm (HP:0002617)1.62118227
129Dysmetria (HP:0001310)1.60860635
130Flared metaphyses (HP:0003015)1.60399443
131Urethral obstruction (HP:0000796)1.59626169
132Trigonocephaly (HP:0000243)1.58883762
133Abnormality of the phalanges of the hallux (HP:0010057)1.58503530
134Embryonal renal neoplasm (HP:0011794)1.58499864
135Postural instability (HP:0002172)1.58274158
136Thickened helices (HP:0000391)1.58195424
137Focal seizures (HP:0007359)1.57708747
138Hammertoe (HP:0001765)1.57176274
139Milia (HP:0001056)1.56647747
140Oligodactyly (hands) (HP:0001180)1.56286728
141Visceral angiomatosis (HP:0100761)1.55845362
142Large earlobe (HP:0009748)1.55747701
143Skin tags (HP:0010609)1.54741266
144Tracheomalacia (HP:0002779)1.54604207
145Hypochromic microcytic anemia (HP:0004840)1.54515798
146Enlarged penis (HP:0000040)1.54459369
147Urinary bladder sphincter dysfunction (HP:0002839)1.54456209
148Supernumerary bones of the axial skeleton (HP:0009144)1.54183988
149Bowed forearm bones (HP:0003956)1.54164771
150Bowing of the arm (HP:0006488)1.54164771
151Annular pancreas (HP:0001734)1.54059948
152Transitional cell carcinoma of the bladder (HP:0006740)1.53094103
153Progressive external ophthalmoplegia (HP:0000590)1.52965931
154Visual hallucinations (HP:0002367)1.52747144
155Hamartoma (HP:0010566)1.52537099
156Abnormality of ocular smooth pursuit (HP:0000617)1.52405440
157Esophageal atresia (HP:0002032)1.52293153
158Panhypogammaglobulinemia (HP:0003139)1.51978336
159Smooth philtrum (HP:0000319)1.51974271
160Lower limb amyotrophy (HP:0007210)1.51869780
161Recurrent viral infections (HP:0004429)1.51829145
162Genetic anticipation (HP:0003743)1.51676233
163Abnormality of the aortic arch (HP:0012303)1.51295212
164Deep palmar crease (HP:0006191)1.51084712
165Hemangiomatosis (HP:0007461)1.51054050
166Relative macrocephaly (HP:0004482)1.49808576
167Broad metatarsal (HP:0001783)1.49335134
168Renal duplication (HP:0000075)1.48736318
169Open mouth (HP:0000194)1.48648414
170Bowel incontinence (HP:0002607)1.48575800
171Abnormality of binocular vision (HP:0011514)1.48334142
172Cystic hygroma (HP:0000476)1.48201216

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP3K103.48811824
2PKN22.89492561
3EEF2K2.87870468
4TRIB32.58051599
5SIK22.42255042
6PRPF4B2.35945227
7SMG12.25024356
8FGFR22.20017887
9CDK122.14960112
10MAP4K11.94654202
11MAP3K131.92139638
12CAMK1G1.82345768
13PTK61.79251090
14ICK1.74766563
15TYRO31.68830792
16BRD41.55872924
17MAP3K71.55067343
18SIK11.53786209
19GRK61.47357390
20RIPK11.46763434
21SRPK11.36531618
22RET1.33016495
23YES11.31334987
24CAMK1D1.30673265
25ALK1.28738834
26MKNK11.27339174
27RPS6KA41.26719178
28TTN1.25385453
29FGFR31.23795289
30CDK61.23361624
31PRKCH1.23173468
32PDGFRA1.20012953
33PDGFRB1.19405810
34NEK61.16394589
35KSR21.16336533
36BMX1.16167299
37CDC71.15701823
38MAP3K91.14393015
39SGK31.10094350
40ITK1.08911227
41AKT31.08503256
42PAK61.08070410
43DMPK1.07636208
44MAPK111.07046884
45EPHA41.05724900
46LATS11.04664539
47PASK1.03705712
48LATS21.02719232
49STK111.01794493
50FGFR41.01476777
51EPHB11.01099180
52NTRK30.95450747
53MARK20.94831676
54HIPK20.94454132
55WNK10.93525377
56LRRK20.92725669
57SCYL20.91419966
58MKNK20.91306846
59MTOR0.89410475
60UHMK10.86911671
61TAOK10.86672464
62RIPK40.84894162
63MAPK100.84249481
64RPS6KB10.84106292
65TAF10.83999324
66KSR10.82487574
67MAP3K140.82459900
68MAP3K20.82024978
69FES0.80522774
70JAK10.79947677
71BRSK20.79381509
72STK100.79055917
73FGFR10.79029627
74HCK0.78963299
75CDK40.78769339
76RPS6KL10.78599743
77RPS6KC10.78599743
78DAPK20.78306571
79CSNK1A1L0.77956422
80IRAK20.76503161
81PRKD20.76221352
82CAMKK10.76164689
83ATR0.73203039
84FGR0.72308173
85PAK20.72062580
86NEK90.70961923
87MAP2K30.70311305
88PRKCQ0.70230541
89MAP3K40.70094821
90JAK20.68683055
91CDK30.67926602
92PNCK0.67396707
93PTK20.66910783
94PAK30.66549902
95PRKD30.66051955
96SGK20.65576792
97MAP3K60.64478351
98PDK10.63853869
99CSK0.63370937
100CHEK10.63308609
101CDK70.62686077
102CDK90.62468929
103SGK10.61767820
104CDK20.61707308
105TTK0.61365089
106MET0.61083313
107TNK20.60418772
108RPS6KA60.57987263
109DDR20.57684626
110CSNK1G20.57563049
111CDC42BPA0.57537303
112NEK20.57522358
113PRKD10.57463058
114CLK10.56689029
115CDK50.56224505
116NTRK20.55986338
117FYN0.55885488
118CSNK1D0.55407264
119RAF10.55335798
120SGK2230.54404488
121SGK4940.54404488
122RPS6KA20.52422446
123LCK0.51112603
124MAP2K40.51070901
125CSF1R0.51067654
126CDK10.50961488
127RPS6KB20.50386741
128FRK0.49975888
129DYRK1B0.49646951
130STK30.49454287
131TRPM70.48749128
132PRKAA20.48680690
133TYK20.48476598
134MELK0.48141590
135ATM0.47568632
136MAPK70.44630508
137GSK3B0.43988100
138BTK0.43105288
139CHEK20.42433043
140MAPK120.42340562
141RPS6KA10.41766908
142MAPK140.39334631
143MAPK80.38942169
144JAK30.37796323
145ERBB30.37256587
146PRKAA10.36723928

Predicted pathways (KEGG)

RankGene SetZ-score
1Nitrogen metabolism_Homo sapiens_hsa009102.58559766
2mRNA surveillance pathway_Homo sapiens_hsa030151.77912394
3Long-term potentiation_Homo sapiens_hsa047201.69250641
4Lysine degradation_Homo sapiens_hsa003101.66046234
5B cell receptor signaling pathway_Homo sapiens_hsa046621.59385002
6mTOR signaling pathway_Homo sapiens_hsa041501.54892557
7T cell receptor signaling pathway_Homo sapiens_hsa046601.53054618
8Chronic myeloid leukemia_Homo sapiens_hsa052201.52306404
9Thyroid cancer_Homo sapiens_hsa052161.49344697
10Phosphatidylinositol signaling system_Homo sapiens_hsa040701.45799580
11Type II diabetes mellitus_Homo sapiens_hsa049301.40872089
12Non-small cell lung cancer_Homo sapiens_hsa052231.38635794
13Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.35910107
14Prolactin signaling pathway_Homo sapiens_hsa049171.34589816
15Glutamatergic synapse_Homo sapiens_hsa047241.30085571
16Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049601.29041033
17Dorso-ventral axis formation_Homo sapiens_hsa043201.28667906
18Cell cycle_Homo sapiens_hsa041101.27415363
19Primary immunodeficiency_Homo sapiens_hsa053401.25107268
20Glioma_Homo sapiens_hsa052141.24596923
21Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.24533047
22VEGF signaling pathway_Homo sapiens_hsa043701.21010129
23Salivary secretion_Homo sapiens_hsa049701.20007203
24Spliceosome_Homo sapiens_hsa030401.19390271
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.19271721
26Renal cell carcinoma_Homo sapiens_hsa052111.18209022
27Gastric acid secretion_Homo sapiens_hsa049711.17073681
28Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049641.16677227
29Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.14376891
30Estrogen signaling pathway_Homo sapiens_hsa049151.13518490
31ErbB signaling pathway_Homo sapiens_hsa040121.13357522
32Renin secretion_Homo sapiens_hsa049241.12266372
33Hepatitis B_Homo sapiens_hsa051611.10888304
34Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.10222177
35Long-term depression_Homo sapiens_hsa047301.09588546
36Viral carcinogenesis_Homo sapiens_hsa052031.08508740
37Circadian entrainment_Homo sapiens_hsa047131.04734063
38Morphine addiction_Homo sapiens_hsa050321.03902439
39Endometrial cancer_Homo sapiens_hsa052131.02732769
40Choline metabolism in cancer_Homo sapiens_hsa052311.02182989
41Systemic lupus erythematosus_Homo sapiens_hsa053221.01708569
42Pancreatic cancer_Homo sapiens_hsa052121.01605931
43Small cell lung cancer_Homo sapiens_hsa052221.01496236
44Insulin resistance_Homo sapiens_hsa049311.01184593
45Phospholipase D signaling pathway_Homo sapiens_hsa040721.00567008
46Proteoglycans in cancer_Homo sapiens_hsa052050.99747464
47Platelet activation_Homo sapiens_hsa046110.99609173
48Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.99384137
49Neurotrophin signaling pathway_Homo sapiens_hsa047220.99108082
50GnRH signaling pathway_Homo sapiens_hsa049120.98867644
51Thyroid hormone signaling pathway_Homo sapiens_hsa049190.98597707
52Dopaminergic synapse_Homo sapiens_hsa047280.98435737
53MicroRNAs in cancer_Homo sapiens_hsa052060.96861750
54Oxytocin signaling pathway_Homo sapiens_hsa049210.96129454
55Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.95672046
56cGMP-PKG signaling pathway_Homo sapiens_hsa040220.95462403
57Colorectal cancer_Homo sapiens_hsa052100.94606565
58MAPK signaling pathway_Homo sapiens_hsa040100.94595119
59Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.92794128
60Bladder cancer_Homo sapiens_hsa052190.92512229
61Alcoholism_Homo sapiens_hsa050340.92468347
62Bile secretion_Homo sapiens_hsa049760.92458179
63Axon guidance_Homo sapiens_hsa043600.91915018
64Carbohydrate digestion and absorption_Homo sapiens_hsa049730.91059907
65Olfactory transduction_Homo sapiens_hsa047400.91029356
66Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.91013840
67Cholinergic synapse_Homo sapiens_hsa047250.90468960
68Amphetamine addiction_Homo sapiens_hsa050310.90320868
69Inositol phosphate metabolism_Homo sapiens_hsa005620.89926867
70Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.89865598
71Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.88835734
72GABAergic synapse_Homo sapiens_hsa047270.88788542
73Acute myeloid leukemia_Homo sapiens_hsa052210.88660306
74Longevity regulating pathway - mammal_Homo sapiens_hsa042110.87500132
75Focal adhesion_Homo sapiens_hsa045100.87048595
76Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.86212923
77cAMP signaling pathway_Homo sapiens_hsa040240.84776376
78Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.84192261
79Prostate cancer_Homo sapiens_hsa052150.82910386
80Osteoclast differentiation_Homo sapiens_hsa043800.82391804
81Chemokine signaling pathway_Homo sapiens_hsa040620.82014370
82Melanogenesis_Homo sapiens_hsa049160.81543028
83DNA replication_Homo sapiens_hsa030300.81090751
84Other glycan degradation_Homo sapiens_hsa005110.79414259
85HTLV-I infection_Homo sapiens_hsa051660.78518348
86Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.78408124
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.78288617
88Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.77237654
89RNA transport_Homo sapiens_hsa030130.76647390
90Central carbon metabolism in cancer_Homo sapiens_hsa052300.76024404
91Gap junction_Homo sapiens_hsa045400.75897737
92Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.75765913
93Hepatitis C_Homo sapiens_hsa051600.75442079
94Transcriptional misregulation in cancer_Homo sapiens_hsa052020.75439211
95Thyroid hormone synthesis_Homo sapiens_hsa049180.73756333
96Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.73383738
97AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.73343848
98Insulin secretion_Homo sapiens_hsa049110.73194065
99Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.73057243
100Rap1 signaling pathway_Homo sapiens_hsa040150.72605628
101FoxO signaling pathway_Homo sapiens_hsa040680.71011646
102HIF-1 signaling pathway_Homo sapiens_hsa040660.70007034
103Fatty acid biosynthesis_Homo sapiens_hsa000610.69546622
104Vascular smooth muscle contraction_Homo sapiens_hsa042700.69111659
105Adherens junction_Homo sapiens_hsa045200.69095764
106Non-homologous end-joining_Homo sapiens_hsa034500.68700065
107Nicotine addiction_Homo sapiens_hsa050330.68127344
108AMPK signaling pathway_Homo sapiens_hsa041520.67860771
109Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.67792980
110Insulin signaling pathway_Homo sapiens_hsa049100.66703956
111Pancreatic secretion_Homo sapiens_hsa049720.66016264
112ABC transporters_Homo sapiens_hsa020100.65740626
113Cocaine addiction_Homo sapiens_hsa050300.64556719
114Leukocyte transendothelial migration_Homo sapiens_hsa046700.63864990
115Toxoplasmosis_Homo sapiens_hsa051450.63598951
116Circadian rhythm_Homo sapiens_hsa047100.63101167
117Arginine biosynthesis_Homo sapiens_hsa002200.62920197
118Sphingolipid signaling pathway_Homo sapiens_hsa040710.62765727
119Herpes simplex infection_Homo sapiens_hsa051680.61949741
120Glucagon signaling pathway_Homo sapiens_hsa049220.61935949
121Wnt signaling pathway_Homo sapiens_hsa043100.61766437
122Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.61731455
123Pathways in cancer_Homo sapiens_hsa052000.61398758
124Basal cell carcinoma_Homo sapiens_hsa052170.61397690
125Regulation of actin cytoskeleton_Homo sapiens_hsa048100.61115660
126Notch signaling pathway_Homo sapiens_hsa043300.60670645
127Measles_Homo sapiens_hsa051620.58782451
128Melanoma_Homo sapiens_hsa052180.57924765
129TGF-beta signaling pathway_Homo sapiens_hsa043500.55936282
130Influenza A_Homo sapiens_hsa051640.55855672
131Apoptosis_Homo sapiens_hsa042100.55463056
132Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.53150685
133Hippo signaling pathway_Homo sapiens_hsa043900.52712680
134Jak-STAT signaling pathway_Homo sapiens_hsa046300.44319754
135p53 signaling pathway_Homo sapiens_hsa041150.43664095

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