CROCC2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1epithelial cilium movement (GO:0003351)9.17714158
2left/right axis specification (GO:0070986)8.62819933
3cilium or flagellum-dependent cell motility (GO:0001539)8.32530340
4ventricular system development (GO:0021591)7.89124786
5motile cilium assembly (GO:0044458)7.54258580
6regulation of cilium movement (GO:0003352)7.24557078
7epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287)7.19117877
8primary alcohol catabolic process (GO:0034310)6.86468206
9negative regulation of glycogen biosynthetic process (GO:0045719)6.31449073
10vitamin transmembrane transport (GO:0035461)6.18002470
11ethanol metabolic process (GO:0006067)6.05826658
12tolerance induction (GO:0002507)5.97932389
13GTP biosynthetic process (GO:0006183)5.70130614
14nucleoside diphosphate phosphorylation (GO:0006165)5.68621738
15negative regulation of glycogen metabolic process (GO:0070874)5.42588104
16diterpenoid biosynthetic process (GO:0016102)5.30807121
17UTP biosynthetic process (GO:0006228)5.23344709
18microtubule bundle formation (GO:0001578)5.19149045
19cilium organization (GO:0044782)5.10483339
20UTP metabolic process (GO:0046051)5.09524331
21response to xenobiotic stimulus (GO:0009410)5.05413454
22one-carbon compound transport (GO:0019755)5.04448546
23negative regulation of humoral immune response (GO:0002921)4.89655607
24intraciliary transport (GO:0042073)4.88470244
25regulation of germinal center formation (GO:0002634)4.86820699
26pyrimidine-containing compound transmembrane transport (GO:0072531)4.77986895
27cilium assembly (GO:0042384)4.66660016
28establishment of apical/basal cell polarity (GO:0035089)4.60637327
29regulation of energy homeostasis (GO:2000505)4.54102271
30negative regulation of T cell differentiation in thymus (GO:0033085)4.47129265
31ethanol oxidation (GO:0006069)4.46825464
32protein localization to cilium (GO:0061512)4.43762296
33regulation of interleukin-5 production (GO:0032674)4.42254683
34sperm capacitation (GO:0048240)4.27578359
35negative regulation of toll-like receptor 4 signaling pathway (GO:0034144)4.24946344
36lung epithelium development (GO:0060428)4.21882238
37regulation of microtubule-based movement (GO:0060632)4.19405179
38establishment of monopolar cell polarity (GO:0061162)4.18947176
39establishment or maintenance of monopolar cell polarity (GO:0061339)4.18947176
40cilium morphogenesis (GO:0060271)4.18639482
41G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:00071994.10006057
42regulation of tolerance induction (GO:0002643)4.06304374
43regulation of interleukin-13 production (GO:0032656)3.96315575
44positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:003603.93825813
45regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)3.92935536
46endocardial cushion morphogenesis (GO:0003203)3.89797831
47microtubule-based movement (GO:0007018)3.85331651
48negative regulation of immunoglobulin mediated immune response (GO:0002890)3.80645601
49negative regulation of B cell mediated immunity (GO:0002713)3.80645601
50cellular component assembly involved in morphogenesis (GO:0010927)3.78674741
51cytoplasmic microtubule organization (GO:0031122)3.65986335
52retinoic acid metabolic process (GO:0042573)3.59015604
53positive regulation of smoothened signaling pathway (GO:0045880)3.57778446
54lateral ventricle development (GO:0021670)3.56377025
55regulation of NFAT protein import into nucleus (GO:0051532)3.53106643
56glomerular epithelial cell development (GO:0072310)3.51577735
57hydrogen peroxide biosynthetic process (GO:0050665)3.51576702
58otic vesicle formation (GO:0030916)3.51230110
59negative regulation of inclusion body assembly (GO:0090084)3.49137431
60regulation of pigment cell differentiation (GO:0050932)3.48478170
61CTP metabolic process (GO:0046036)3.47318766
62CTP biosynthetic process (GO:0006241)3.47318766
63establishment or maintenance of apical/basal cell polarity (GO:0035088)3.46436356
64establishment or maintenance of bipolar cell polarity (GO:0061245)3.46436356
65left/right pattern formation (GO:0060972)3.46244593
66terpenoid biosynthetic process (GO:0016114)3.46145504
67heart valve formation (GO:0003188)3.44513671
68exogenous drug catabolic process (GO:0042738)3.38442216
69determination of bilateral symmetry (GO:0009855)3.38274523
70cell projection assembly (GO:0030031)3.37055379
71determination of left/right symmetry (GO:0007368)3.34985466
72specification of symmetry (GO:0009799)3.31164134
73pyrimidine ribonucleoside triphosphate metabolic process (GO:0009208)3.29715534
74guanosine-containing compound biosynthetic process (GO:1901070)3.28360020
75pyrimidine ribonucleoside triphosphate biosynthetic process (GO:0009209)3.27863225
76microtubule depolymerization (GO:0007019)3.21266098
77epithelial cell differentiation involved in prostate gland development (GO:0060742)3.19806829
78phosphorelay signal transduction system (GO:0000160)3.18881337
79reactive oxygen species biosynthetic process (GO:1903409)3.17181889
80regulation of establishment of planar polarity involved in neural tube closure (GO:0090178)3.16428569
81positive regulation of extracellular matrix organization (GO:1903055)3.14858272
82lung-associated mesenchyme development (GO:0060484)3.13867758
83notochord development (GO:0030903)3.13420231
84planar cell polarity pathway involved in neural tube closure (GO:0090179)3.10773307
85positive regulation of developmental pigmentation (GO:0048087)3.09200636
86regulation of respiratory gaseous exchange (GO:0043576)3.08869352
87regulation of hippo signaling (GO:0035330)3.08545074
88nucleotide phosphorylation (GO:0046939)3.07221945
89brain morphogenesis (GO:0048854)3.06597941
90microtubule polymerization or depolymerization (GO:0031109)3.06373382
91O-glycan processing (GO:0016266)3.05821340
92paraxial mesoderm development (GO:0048339)3.05504515
93axon ensheathment in central nervous system (GO:0032291)3.03166570
94central nervous system myelination (GO:0022010)3.03166570
95ADP metabolic process (GO:0046031)3.01008712
96primary alcohol metabolic process (GO:0034308)2.99869521
97regulation of extracellular matrix organization (GO:1903053)2.99710068
98embryonic camera-type eye development (GO:0031076)2.95325752
99negative regulation of catenin import into nucleus (GO:0035414)2.95009323
100camera-type eye morphogenesis (GO:0048593)2.94753606
101smoothened signaling pathway (GO:0007224)2.93378685
102hypotonic response (GO:0006971)2.92309416
103establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197)2.91628650
104multicellular organismal aging (GO:0010259)2.90448776
105negative regulation of adaptive immune response (GO:0002820)2.87780535
106cardiovascular system development (GO:0072358)2.84179067
107regulation of extracellular matrix disassembly (GO:0010715)2.83864464
108mesenchyme morphogenesis (GO:0072132)2.83513426
109pyrimidine nucleoside triphosphate biosynthetic process (GO:0009148)2.83402430
110epithelial to mesenchymal transition involved in endocardial cushion formation (GO:0003198)2.74484297
111establishment of planar polarity (GO:0001736)2.74439131
112establishment of tissue polarity (GO:0007164)2.74439131
113retinol metabolic process (GO:0042572)2.73151129
114nephron tubule formation (GO:0072079)2.72212342
115neuronal stem cell maintenance (GO:0097150)2.71863246
116negative regulation of lymphocyte mediated immunity (GO:0002707)2.71658166
117phospholipase C-activating dopamine receptor signaling pathway (GO:0060158)2.71450692
118multicellular organismal water homeostasis (GO:0050891)2.71394243
119pyrimidine nucleoside triphosphate metabolic process (GO:0009147)2.71276082
120regulation of intracellular estrogen receptor signaling pathway (GO:0033146)2.71144073
121embryonic cranial skeleton morphogenesis (GO:0048701)2.70654157
122regulation of interleukin-6 biosynthetic process (GO:0045408)2.69953094
123regulation of glucan biosynthetic process (GO:0010962)2.68679521
124regulation of glycogen biosynthetic process (GO:0005979)2.68679521
125lens fiber cell development (GO:0070307)2.68384489
126regulation of response to osmotic stress (GO:0047484)2.68371124
127regulation of apoptotic cell clearance (GO:2000425)2.67286251
128regulation of microtubule depolymerization (GO:0031114)2.66708110
129drug catabolic process (GO:0042737)2.66495939
130endothelial cell morphogenesis (GO:0001886)2.65511453
131negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway (GO:1902176)2.64641586
132regulation of smoothened signaling pathway (GO:0008589)2.63233007
133sperm motility (GO:0030317)2.63124466
134negative regulation of chondrocyte differentiation (GO:0032331)2.62473348
135limb bud formation (GO:0060174)2.62110155
136spindle assembly involved in mitosis (GO:0090307)2.60979656
137centriole assembly (GO:0098534)2.60914845
138asymmetric protein localization (GO:0008105)2.60522474
139hippo signaling (GO:0035329)2.58290871
140phosphatidylcholine biosynthetic process (GO:0006656)2.58026615
141regulation of glucose import in response to insulin stimulus (GO:2001273)2.56546656
142positive regulation of tolerance induction (GO:0002645)2.54632370
143regulation of autophagic vacuole assembly (GO:2000785)2.54220077
144glutathione derivative biosynthetic process (GO:1901687)2.53054937
145glutathione derivative metabolic process (GO:1901685)2.53054937
146progesterone metabolic process (GO:0042448)2.52057102
147iron ion import (GO:0097286)2.47263544
148carnitine metabolic process (GO:0009437)2.46993409
149microtubule-based process (GO:0007017)2.37608888
150excretion (GO:0007588)2.37551357
151polyol transport (GO:0015791)2.37462978
152regulation of peroxisome proliferator activated receptor signaling pathway (GO:0035358)2.36657262
153hydrogen peroxide catabolic process (GO:0042744)2.35612503
154dichotomous subdivision of an epithelial terminal unit (GO:0060600)2.33696433
155negative regulation of adaptive immune response based on somatic recombination of immune receptors b2.33189086
156aldehyde catabolic process (GO:0046185)2.32212621
157regulation of cilium assembly (GO:1902017)2.31403694
158water homeostasis (GO:0030104)2.31102764
159phosphatidylethanolamine biosynthetic process (GO:0006646)2.30071255
160lateral sprouting from an epithelium (GO:0060601)2.28848401
161organelle assembly (GO:0070925)2.26967714
162cilium movement (GO:0003341)13.8570198
163axonemal dynein complex assembly (GO:0070286)12.8326150
164axoneme assembly (GO:0035082)10.5607840

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat4.41995387
2CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.45977699
3TRIM28_21343339_ChIP-Seq_HEK293_Human3.39758044
4FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human3.04017884
5TP63_17297297_ChIP-ChIP_HaCaT_Human2.67321390
6DROSHA_22980978_ChIP-Seq_HELA_Human2.46954999
7ESR1_15608294_ChIP-ChIP_MCF-7_Human2.41166625
8NR4A2_19515692_ChIP-ChIP_MN9D_Mouse2.39066725
9ESR1_20079471_ChIP-ChIP_T-47D_Human2.31973376
10SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.24121411
11ZFP281_18358816_ChIP-ChIP_MESCs_Mouse2.15211842
12TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.13368156
13NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.02895568
14EZH2_27294783_Chip-Seq_ESCs_Mouse1.98705138
15AR_21572438_ChIP-Seq_LNCaP_Human1.95638868
16SMC4_20622854_ChIP-Seq_HELA_Human1.93794598
17RBPJ_22232070_ChIP-Seq_NCS_Mouse1.90393388
18STAT6_21828071_ChIP-Seq_BEAS2B_Human1.89553043
19RUNX1_27514584_Chip-Seq_MCF-7_Human1.88529907
20ESR2_21235772_ChIP-Seq_MCF-7_Human1.85618848
21GATA1_26923725_Chip-Seq_HPCs_Mouse1.83601709
22CTNNB1_20615089_ChIP-ChIP_FETAL_BRAIN_Human1.72288141
23ESR1_21235772_ChIP-Seq_MCF-7_Human1.70905295
24KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.70463495
25KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.70463495
26KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.70463495
27SOX2_27498859_Chip-Seq_STOMACH_Mouse1.67183875
28STAT1_20625510_ChIP-Seq_HELA_Human1.66668534
29PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.65732395
30MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human1.61030956
31EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.58308191
32ELF1_20517297_ChIP-Seq_JURKAT_Human1.56376027
33WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.55446501
34JARID2_20075857_ChIP-Seq_MESCs_Mouse1.54563575
35STAT6_20620947_ChIP-Seq_CD4_POS_T_Human1.54430836
36GATA1_19941826_ChIP-Seq_K562_Human1.53387400
37TP63_22573176_ChIP-Seq_HFKS_Human1.52932513
38ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.52342707
39ZFP281_27345836_Chip-Seq_ESCs_Mouse1.52123521
40SUZ12_18555785_ChIP-Seq_MESCs_Mouse1.50575695
41SOX2_18555785_ChIP-Seq_MESCs_Mouse1.50464617
42SUZ12_18692474_ChIP-Seq_MESCs_Mouse1.50262349
43SUZ12_18692474_ChIP-Seq_MEFs_Mouse1.49678384
44P63_26484246_Chip-Seq_KERATINOCYTES_Human1.49549776
45FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human1.47339034
46ZFP281_18757296_ChIP-ChIP_E14_Mouse1.46731124
47IRF8_22096565_ChIP-ChIP_GC-B_Human1.45993594
48LXR_22292898_ChIP-Seq_THP-1_Human1.45771511
49SUZ12_27294783_Chip-Seq_ESCs_Mouse1.45725703
50SUZ12_16625203_ChIP-ChIP_MESCs_Mouse1.44344803
51CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.43794797
52E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.43560562
53WT1_19549856_ChIP-ChIP_CCG9911_Human1.43255088
54RING1B_27294783_Chip-Seq_ESCs_Mouse1.42734199
55SMAD2/3_21741376_ChIP-Seq_ESCs_Human1.42430356
56PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.41264589
57RNF2_18974828_ChIP-Seq_MESCs_Mouse1.40808258
58EZH2_18974828_ChIP-Seq_MESCs_Mouse1.40808258
59TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.40478855
60RING1B_27294783_Chip-Seq_NPCs_Mouse1.40262901
61SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.39027918
62SOX9_24532713_ChIP-Seq_HFSC_Mouse1.37640523
63EED_16625203_ChIP-ChIP_MESCs_Mouse1.36404546
64STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.34962488
65CLOCK_20551151_ChIP-Seq_293T_Human1.34692799
66AR_21915096_ChIP-Seq_LNCaP-1F5_Human1.34593655
67KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human1.34164706
68JARID2_20064375_ChIP-Seq_MESCs_Mouse1.33859499
69RNF2_27304074_Chip-Seq_NSC_Mouse1.33780958
70ELK4_26923725_Chip-Seq_MESODERM_Mouse1.33296381
71TP63_23658742_ChIP-Seq_EP156T_Human1.33148430
72RAD21_21589869_ChIP-Seq_MESCs_Mouse1.31967801
73LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30912778
74P68_20966046_ChIP-Seq_HELA_Human1.30350273
75EZH2_27304074_Chip-Seq_ESCs_Mouse1.29711998
76SUZ12_18974828_ChIP-Seq_MESCs_Mouse1.29498538
77TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.29402314
78RNF2_27304074_Chip-Seq_ESCs_Mouse1.29165115
79TDRD3_21172665_ChIP-Seq_MCF-7_Human1.28888974
80TP53_20018659_ChIP-ChIP_R1E_Mouse1.28489423
81ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.26338801
82SMAD4_21799915_ChIP-Seq_A2780_Human1.25878255
83CTNNB1_20460455_ChIP-Seq_HCT116_Human1.24686000
84SOX9_26525672_Chip-Seq_Limbbuds_Mouse1.24018121
85STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.23597923
86RACK7_27058665_Chip-Seq_MCF-7_Human1.23452823
87CDX2_20551321_ChIP-Seq_CACO-2_Human1.22411645
88TP53_18474530_ChIP-ChIP_U2OS_Human1.21364922
89ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human1.21052855
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.19497908
91CEBPB_23403033_ChIP-Seq_LIVER_Mouse1.19373187
92CTBP2_25329375_ChIP-Seq_LNCAP_Human1.18923177
93SPI1_23127762_ChIP-Seq_K562_Human1.18618466
94SMRT_27268052_Chip-Seq_Bcells_Human1.18164337
95POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.17874966
96ZNF217_24962896_ChIP-Seq_MCF-7_Human1.17780728
97RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.16828551
98ZIC3_20872845_ChIP-ChIP_MESCs_Mouse1.16170199
99SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.15675675
100PHF8_20622854_ChIP-Seq_HELA_Human1.15626905
101CTCF_27219007_Chip-Seq_Bcells_Human1.15511207
102GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.15398975
103SALL4_18804426_ChIP-ChIP_MESCs_Mouse1.15343206
104SOX2_18358816_ChIP-ChIP_MESCs_Mouse1.15206837
105MTF2_20144788_ChIP-Seq_MESCs_Mouse1.14661447
106CTCF_20526341_ChIP-Seq_ESCs_Human1.14568765
107VDR_20736230_ChIP-Seq_LYMPHOBLASTOID_Human1.14249320
108SOX2_20726797_ChIP-Seq_SW620_Human1.14225537
109KDM2B_26808549_Chip-Seq_SUP-B15_Human1.14100378
110FOXM1_26456572_ChIP-Seq_MCF-7_Human1.13937829
111FOXA2_19822575_ChIP-Seq_HepG2_Human1.13881213
112CREB1_26743006_Chip-Seq_LNCaP_Human1.13411439
113FOXO3_23340844_ChIP-Seq_DLD1_Human1.12932448
114YY1_22570637_ChIP-Seq_MALME-3M_Human1.12757324
115WT1_25993318_ChIP-Seq_PODOCYTE_Human1.12651236
116RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.12565990
117FOXA1_25552417_ChIP-Seq_VCAP_Human1.12289000
118SMAD3_21741376_ChIP-Seq_EPCs_Human1.12186418
119NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.12086920
120SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.11362228
121OLIG2_26023283_ChIP-Seq_AINV15_Mouse1.10874400
122SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.10255130
123AHR_22903824_ChIP-Seq_MCF-7_Human1.09836606
124NACC1_18358816_ChIP-ChIP_MESCs_Mouse1.09292160
125YAP1_20516196_ChIP-Seq_MESCs_Mouse1.08976402
126GATA2_19941826_ChIP-Seq_K562_Human1.08952304
127VDR_24763502_ChIP-Seq_THP-1_Human1.08424322
128PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.07853449
129RARG_19884340_ChIP-ChIP_MEFs_Mouse1.07831420
130RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.07295363
131PCGF2_27294783_Chip-Seq_NPCs_Mouse1.07029112
132TBX3_20139965_ChIP-Seq_ESCs_Mouse1.06992301
133E2F7_22180533_ChIP-Seq_HELA_Human1.06987924
134SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.06908719
135P300_27268052_Chip-Seq_Bcells_Human1.06656627
136E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.05687996
137TBX3_20139965_ChIP-Seq_MESCs_Mouse1.05559548
138STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.05186843
139PIAS1_25552417_ChIP-Seq_VCAP_Human1.05058012
140SIN3B_21632747_ChIP-Seq_MESCs_Mouse1.04830753
141CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.04498709
142BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.04005177
143ISL1_27105846_Chip-Seq_CPCs_Mouse1.02554929
144TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.02326977
145LXR_22158963_ChIP-Seq_LIVER_Mouse1.01853369
146TCF3_18692474_ChIP-Seq_MEFs_Mouse1.01517783
147FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human1.00851998
148E2F1_20622854_ChIP-Seq_HELA_Human1.00395116
149BCOR_27268052_Chip-Seq_Bcells_Human1.00291436
150CREB1_26743006_Chip-Seq_LNCaP-abl_Human0.99579744
151VDR_22108803_ChIP-Seq_LS180_Human0.98710981
152GATA4_25053715_ChIP-Seq_YYC3_Human0.98461574
153GATA1_19941827_ChIP-Seq_MEL_Mouse0.98172708
154ZNF263_19887448_ChIP-Seq_K562_Human0.98027238
155BCL6_27268052_Chip-Seq_Bcells_Human0.97368633
156IRF8_27001747_Chip-Seq_BMDM_Mouse0.97360530
157IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.97352674
158RUNX_20019798_ChIP-Seq_JUKART_Human0.95757298
159ETV1_20927104_ChIP-Seq_GIST48_Human0.95466577
160CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.95367708
161SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.94992003
162NR3C1_21868756_ChIP-Seq_MCF10A_Human0.94663741
163KDM2B_26808549_Chip-Seq_K562_Human0.94389243
164CJUN_26792858_Chip-Seq_BT549_Human0.93777633
165SA1_27219007_Chip-Seq_ERYTHROID_Human0.93521488
166TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.93502195
167THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.92993548
168CEBPB_22108803_ChIP-Seq_LS180_Human0.92609570
169KLF5_25053715_ChIP-Seq_YYC3_Human0.92535739
170TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.92413769
171BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.91644047
172MAF_26560356_Chip-Seq_TH1_Human0.91475602
173TOP2B_26459242_ChIP-Seq_MCF-7_Human0.91256881
174SOX2_21211035_ChIP-Seq_LN229_Human0.90891177
175FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.89756779
176P63_20808887_ChIP-Seq_KERATINOCYTES_Human0.89313536
177PPAR_26484153_Chip-Seq_NCI-H1993_Human0.88790165
178GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.88384523
179KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.87953525
180TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human0.87848726
181TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.86416783
182HNFA_21074721_ChIP-Seq_CACO-2_Human0.85582565
183RUNX1_22897851_ChIP-Seq_JUKARTE6-1_Human0.84682996
184RUNX1_22412390_ChIP-Seq_EML_Mouse0.84414246
185CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.84229315

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color7.01376582
2MP0002653_abnormal_ependyma_morphology6.60161089
3MP0002132_abnormal_respiratory_system6.19373725
4MP0008875_abnormal_xenobiotic_pharmacok6.16141703
5MP0005623_abnormal_meninges_morphology3.82256495
6MP0002277_abnormal_respiratory_mucosa3.65401882
7MP0010030_abnormal_orbit_morphology3.57264701
8MP0004043_abnormal_pH_regulation3.46406100
9MP0004133_heterotaxia3.04458333
10MP0001958_emphysema2.84169532
11MP0008438_abnormal_cutaneous_collagen2.84031765
12MP0005083_abnormal_biliary_tract2.64991651
13MP0003878_abnormal_ear_physiology2.40192912
14MP0005377_hearing/vestibular/ear_phenot2.40192912
15MP0003303_peritoneal_inflammation2.26244424
16MP0008004_abnormal_stomach_pH2.25236145
17MP0003656_abnormal_erythrocyte_physiolo2.11526917
18MP0004272_abnormal_basement_membrane2.07636011
19MP0002249_abnormal_larynx_morphology2.03200575
20MP0002168_other_aberrant_phenotype2.01423922
21MP0004381_abnormal_hair_follicle1.98402937
22MP0002282_abnormal_trachea_morphology1.96619106
23MP0001765_abnormal_ion_homeostasis1.85116617
24MP0006082_CNS_inflammation1.84602759
25MP0010155_abnormal_intestine_physiology1.84114700
26MP0005503_abnormal_tendon_morphology1.81508621
27MP0000778_abnormal_nervous_system1.79503889
28MP0003279_aneurysm1.78075922
29MP0001177_atelectasis1.74834999
30MP0004019_abnormal_vitamin_homeostasis1.74011364
31MP0003122_maternal_imprinting1.73246133
32MP0000678_abnormal_parathyroid_gland1.67499356
33MP0002938_white_spotting1.66559946
34MP0001915_intracranial_hemorrhage1.60342762
35MP0003705_abnormal_hypodermis_morpholog1.58073992
36MP0003937_abnormal_limbs/digits/tail_de1.57607809
37MP0000465_gastrointestinal_hemorrhage1.56622276
38MP0005499_abnormal_olfactory_system1.52798841
39MP0005394_taste/olfaction_phenotype1.52798841
40MP0009250_abnormal_appendicular_skeleto1.52135263
41MP0005387_immune_system_phenotype1.50499547
42MP0001790_abnormal_immune_system1.50499547
43MP0002233_abnormal_nose_morphology1.46253179
44MP0003115_abnormal_respiratory_system1.45223196
45MP0000428_abnormal_craniofacial_morphol1.38352331
46MP0002928_abnormal_bile_duct1.37816189
47MP0002234_abnormal_pharynx_morphology1.36537562
48MP0001835_abnormal_antigen_presentation1.35411687
49MP0004883_abnormal_blood_vessel1.34596870
50MP0002116_abnormal_craniofacial_bone1.34145002
51MP0002405_respiratory_system_inflammati1.33384462
52MP0003123_paternal_imprinting1.32859561
53MP0009384_cardiac_valve_regurgitation1.32297272
54MP0003942_abnormal_urinary_system1.32072412
55MP0008961_abnormal_basal_metabolism1.30712756
56MP0002896_abnormal_bone_mineralization1.30372112
57MP0002089_abnormal_postnatal_growth/wei1.30143660
58MP0003283_abnormal_digestive_organ1.29797398
59MP0004134_abnormal_chest_morphology1.28439086
60MP0001727_abnormal_embryo_implantation1.28027346
61MP0005388_respiratory_system_phenotype1.26980604
62MP0002133_abnormal_respiratory_system1.26980604
63MP0005164_abnormal_response_to1.26764289
64MP0005275_abnormal_skin_tensile1.26674781
65MP0002909_abnormal_adrenal_gland1.26240603
66MP0000049_abnormal_middle_ear1.24095341
67MP0000537_abnormal_urethra_morphology1.23514956
68MP0003861_abnormal_nervous_system1.22931292
69MP0003566_abnormal_cell_adhesion1.22888065
70MP0003866_abnormal_defecation1.21640716
71MP0006054_spinal_hemorrhage1.20724796
72MP0010678_abnormal_skin_adnexa1.18890526
73MP0003436_decreased_susceptibility_to1.17893922
74MP0005025_abnormal_response_to1.17201379
75MP0000383_abnormal_hair_follicle1.14015935
76MP0004859_abnormal_synaptic_plasticity1.12660847
77MP0003755_abnormal_palate_morphology1.11653708
78MP0004264_abnormal_extraembryonic_tissu1.11505590
79MP0000462_abnormal_digestive_system1.11394249
80MP0005187_abnormal_penis_morphology1.10109765
81MP0005165_increased_susceptibility_to1.08816376
82MP0005395_other_phenotype1.07653732
83MP0010234_abnormal_vibrissa_follicle1.06421555
84MP0002111_abnormal_tail_morphology1.04671841
85MP0003121_genomic_imprinting1.03878885
86MP0005409_darkened_coat_color1.03648982
87MP0002092_abnormal_eye_morphology1.03306479
88MP0000681_abnormal_thyroid_gland1.01911929
89MP0005636_abnormal_mineral_homeostasis1.00827910
90MP0003075_altered_response_to1.00082318
91MP0003385_abnormal_body_wall1.00009822
92MP0005365_abnormal_bile_salt0.98893891
93MP0000432_abnormal_head_morphology0.98658064
94MP0000762_abnormal_tongue_morphology0.98615117
95MP0005167_abnormal_blood-brain_barrier0.98188812
96MP0002160_abnormal_reproductive_system0.95890908
97MP0002697_abnormal_eye_size0.95612770
98MP0000858_altered_metastatic_potential0.95518943
99MP0002109_abnormal_limb_morphology0.94567223
100MP0001299_abnormal_eye_distance/0.93118437
101MP0001849_ear_inflammation0.92308596
102MP0002136_abnormal_kidney_physiology0.91655643
103MP0002419_abnormal_innate_immunity0.91349273
104MP0005310_abnormal_salivary_gland0.91320082
105MP0003724_increased_susceptibility_to0.90141454
106MP0003828_pulmonary_edema0.89539250
107MP0005508_abnormal_skeleton_morphology0.89409679
108MP0001440_abnormal_grooming_behavior0.89338857
109MP0009643_abnormal_urine_homeostasis0.88964436
110MP0004858_abnormal_nervous_system0.88482286
111MP0005464_abnormal_platelet_physiology0.88099895
112MP0003172_abnormal_lysosome_physiology0.86856470
113MP0002085_abnormal_embryonic_tissue0.86069453
114MP0003935_abnormal_craniofacial_develop0.85822926
115MP0005220_abnormal_exocrine_pancreas0.83747475
116MP0000163_abnormal_cartilage_morphology0.82461444
117MP0006072_abnormal_retinal_apoptosis0.80542556
118MP0001286_abnormal_eye_development0.80051963
119MP0003941_abnormal_skin_development0.79472816
120MP0001851_eye_inflammation0.79239204
121MP0004947_skin_inflammation0.79125769
122MP0002152_abnormal_brain_morphology0.78398734
123MP0003191_abnormal_cellular_cholesterol0.77647946
124MP0004233_abnormal_muscle_weight0.77561273
125MP0004197_abnormal_fetal_growth/weight/0.77436194
126MP0003634_abnormal_glial_cell0.77184310
127MP0001663_abnormal_digestive_system0.76714205
128MP0000685_abnormal_immune_system0.76587170
129MP0002932_abnormal_joint_morphology0.76438610
130MP0005085_abnormal_gallbladder_physiolo0.76394086
131MP0002295_abnormal_pulmonary_circulatio0.74588751
132MP0003119_abnormal_digestive_system0.74441345
133MP0005166_decreased_susceptibility_to0.74281208
134MP0001346_abnormal_lacrimal_gland0.74196400
135MP0001340_abnormal_eyelid_morphology0.72904784
136MP0008789_abnormal_olfactory_epithelium0.72549865
137MP0000566_synostosis0.72059432
138MP0004885_abnormal_endolymph0.72031916
139MP0000647_abnormal_sebaceous_gland0.72026480
140MP0003045_fibrosis0.71832205
141MP0001984_abnormal_olfaction0.71665364
142MP0001533_abnormal_skeleton_physiology0.71450549
143MP0005391_vision/eye_phenotype0.69990210
144MP0002734_abnormal_mechanical_nocicepti0.69862641
145MP0002115_abnormal_skeleton_extremities0.69711507
146MP0003453_abnormal_keratinocyte_physiol0.69317300
147MP0001800_abnormal_humoral_immune0.69124021
148MP0009763_increased_sensitivity_to0.68522739
149MP0000534_abnormal_ureter_morphology0.68320875
150MP0000955_abnormal_spinal_cord0.68205373
151MP0001270_distended_abdomen0.67384935
152MP0001943_abnormal_respiration0.66756503
153MP0002108_abnormal_muscle_morphology0.66153671
154MP0001293_anophthalmia0.66108276
155MP0002254_reproductive_system_inflammat0.65632566
156MP0002084_abnormal_developmental_patter0.64584918
157MP0001175_abnormal_lung_morphology0.64463536
158MP0009765_abnormal_xenobiotic_induced0.64118154
159MP0001845_abnormal_inflammatory_respons0.63555518
160MP0002139_abnormal_hepatobiliary_system0.63538916
161MP0002735_abnormal_chemical_nociception0.63134015
162MP0005076_abnormal_cell_differentiation0.62674838
163MP0009780_abnormal_chondrocyte_physiolo0.62604903
164MP0005248_abnormal_Harderian_gland0.61792245
165MP0001664_abnormal_digestion0.61543679
166MP0003763_abnormal_thymus_physiology0.61170849
167MP0002452_abnormal_antigen_presenting0.61037691
168MP0000249_abnormal_blood_vessel0.60767716
169MP0002876_abnormal_thyroid_physiology0.58709187
170MP0009785_altered_susceptibility_to0.54948363
171MP0005389_reproductive_system_phenotype0.54577498
172MP0003698_abnormal_male_reproductive0.54374990
173MP0001819_abnormal_immune_cell0.54139883
174MP0002723_abnormal_immune_serum0.53395826
175MP0002420_abnormal_adaptive_immunity0.53342600
176MP0001485_abnormal_pinna_reflex0.52834219
177MP0005671_abnormal_response_to0.52728584
178MP0001929_abnormal_gametogenesis0.51415089
179MP0009278_abnormal_bone_marrow0.50680093
180MP0002822_catalepsy0.49250109
181MP0002135_abnormal_kidney_morphology0.49056253

Predicted human phenotypes

RankGene SetZ-score
1Rhinitis (HP:0012384)7.97451723
2Abnormal respiratory epithelium morphology (HP:0012253)6.66789832
3Abnormal respiratory motile cilium morphology (HP:0005938)6.66789832
4Chronic bronchitis (HP:0004469)6.60820925
5Absent/shortened dynein arms (HP:0200106)5.45520093
6Dynein arm defect of respiratory motile cilia (HP:0012255)5.45520093
7Bronchiectasis (HP:0002110)4.66734141
8Nasal polyposis (HP:0100582)4.16718426
9True hermaphroditism (HP:0010459)4.15799813
10Male infertility (HP:0003251)3.98447991
11Pancreatic fibrosis (HP:0100732)3.81072667
12Occipital encephalocele (HP:0002085)3.76534760
13Supernumerary spleens (HP:0009799)3.75932078
14Abnormality of dentin (HP:0010299)3.46609882
15Abnormality of the nasal mucosa (HP:0000433)3.38887786
16Chronic otitis media (HP:0000389)3.31061331
17Neonatal short-limb short stature (HP:0008921)3.30658300
18Cystic liver disease (HP:0006706)3.05880954
19Pancreatic cysts (HP:0001737)2.93496386
20Hyperactive renin-angiotensin system (HP:0000841)2.87063029
21Fibular hypoplasia (HP:0003038)2.78778752
22Abnormal biliary tract physiology (HP:0012439)2.70165543
23Bile duct proliferation (HP:0001408)2.70165543
24Bronchitis (HP:0012387)2.67766805
25Chronic sinusitis (HP:0011109)2.59333248
26Aplasia/Hypoplasia of the tongue (HP:0010295)2.56065839
27Abdominal situs inversus (HP:0003363)2.51546697
28Abnormality of abdominal situs (HP:0011620)2.51546697
29Short nail (HP:0001799)2.47393504
30Median cleft lip (HP:0000161)2.46635710
31Bronchomalacia (HP:0002780)2.43368989
32Infertility (HP:0000789)2.39955056
33Coronal craniosynostosis (HP:0004440)2.36372587
34Abnormality of midbrain morphology (HP:0002418)2.34955874
35Molar tooth sign on MRI (HP:0002419)2.34955874
36Postaxial foot polydactyly (HP:0001830)2.29933786
37Bell-shaped thorax (HP:0001591)2.25763586
38Congenital hepatic fibrosis (HP:0002612)2.24981846
39Large earlobe (HP:0009748)2.23841484
40Premature rupture of membranes (HP:0001788)2.22768073
41Tubulointerstitial nephritis (HP:0001970)2.22642184
42Preaxial hand polydactyly (HP:0001177)2.22334465
43Protrusio acetabuli (HP:0003179)2.20441458
44Recurrent bronchitis (HP:0002837)2.17834294
45Severe Myopia (HP:0011003)2.15574291
46Chronic hepatic failure (HP:0100626)2.13202376
47Missing ribs (HP:0000921)2.12689698
48Anencephaly (HP:0002323)2.10631440
49Pseudobulbar signs (HP:0002200)2.09581977
50Shallow orbits (HP:0000586)2.07436829
51Sclerocornea (HP:0000647)2.06633659
52Absent frontal sinuses (HP:0002688)2.03076401
53Aplasia/Hypoplasia of the fibula (HP:0006492)2.01814945
54Abnormal respiratory motile cilium physiology (HP:0012261)10.9148106
55Respiratory insufficiency due to defective ciliary clearance (HP:0200073)10.6989627
56Abnormal ciliary motility (HP:0012262)10.5809163
57Recurrent otitis media (HP:0000403)1.99938975
58Broad distal phalanx of finger (HP:0009836)1.97804886
59Facial cleft (HP:0002006)1.94213336
60Recurrent sinusitis (HP:0011108)1.91724694
61Long toe (HP:0010511)1.90613772
62Down-sloping shoulders (HP:0200021)1.90161288
63Esophageal atresia (HP:0002032)1.89099311
64Male pseudohermaphroditism (HP:0000037)1.86951452
65Nephronophthisis (HP:0000090)1.83520679
6611 pairs of ribs (HP:0000878)1.82367313
67Abnormality of the renal medulla (HP:0100957)1.81612022
68Omphalocele (HP:0001539)1.80541685
69Asplenia (HP:0001746)1.77262138
70Breech presentation (HP:0001623)1.75640847
71Decreased circulating renin level (HP:0003351)1.69593184
72Renal salt wasting (HP:0000127)1.68817087
73Bifid tongue (HP:0010297)1.68740408
74Broad metatarsal (HP:0001783)1.67423171
75Abnormality of permanent molar morphology (HP:0011071)1.66974092
76Abnormality of the dental root (HP:0006486)1.66974092
77Taurodontia (HP:0000679)1.66974092
78Bladder diverticulum (HP:0000015)1.66889000
79Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.66015939
80Nephropathy (HP:0000112)1.63439196
81Aplasia/Hypoplasia of the spleen (HP:0010451)1.62948185
82Glossoptosis (HP:0000162)1.62775482
83Natal tooth (HP:0000695)1.62125267
84Mesomelia (HP:0003027)1.62015730
85Abnormal umbilical cord blood vessels (HP:0011403)1.61278488
86Single umbilical artery (HP:0001195)1.61278488
87Abnormality of the fetal cardiovascular system (HP:0010948)1.61278488
88Abnormality of molar morphology (HP:0011070)1.60122136
89Abnormality of molar (HP:0011077)1.60122136
90Back pain (HP:0003418)1.59538873
91Gastrointestinal atresia (HP:0002589)1.58801981
92Furrowed tongue (HP:0000221)1.56898474
93Atelectasis (HP:0100750)1.55453962
94Tubular atrophy (HP:0000092)1.54883194
95Medial flaring of the eyebrow (HP:0010747)1.53540353
96Hyperkalemia (HP:0002153)1.52932019
97Congenital primary aphakia (HP:0007707)1.51339454
98Aplasia involving bones of the extremities (HP:0009825)1.49995981
99Aplasia involving bones of the upper limbs (HP:0009823)1.49995981
100Aplasia of the phalanges of the hand (HP:0009802)1.49995981
101Gait imbalance (HP:0002141)1.49981151
102Polycystic kidney dysplasia (HP:0000113)1.49779428
103Arnold-Chiari malformation (HP:0002308)1.49592706
104Abnormality of the dental pulp (HP:0006479)1.48209536
105Abnormality of the 2nd finger (HP:0004100)1.47756311
106Obstructive sleep apnea (HP:0002870)1.46235511
107Atrophic scars (HP:0001075)1.45345460
108Femoral bowing (HP:0002980)1.44185272
109Postaxial hand polydactyly (HP:0001162)1.43893612
110Trigonocephaly (HP:0000243)1.43596851
111Abnormal number of incisors (HP:0011064)1.43273768
112Oculomotor apraxia (HP:0000657)1.41758435
113Abnormality of the diencephalon (HP:0010662)1.41099958
114Hyperaldosteronism (HP:0000859)1.37047925
115Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.36288432
116Absent rod-and cone-mediated responses on ERG (HP:0007688)1.33490132
117Abnormality of the frontal sinuses (HP:0002687)1.30631931
118Glucose intolerance (HP:0000833)1.30142631
119Abnormality of renin-angiotensin system (HP:0000847)1.27530499
120Decreased central vision (HP:0007663)1.24908652
121Abnormality of the distal phalanges of the toes (HP:0010182)1.23741556
122Abnormality of chloride homeostasis (HP:0011422)1.23511528
123Short thorax (HP:0010306)1.22805482
124Recurrent gram-negative bacterial infections (HP:0005420)1.19660625
125Flat acetabular roof (HP:0003180)1.18534432
126Hand muscle atrophy (HP:0009130)1.16046761
127Muscle fiber splitting (HP:0003555)1.14667451
128Cone-shaped epiphyses of the phalanges of the hand (HP:0010230)1.14108576
129Nephrogenic diabetes insipidus (HP:0009806)1.13622637
130Cone-rod dystrophy (HP:0000548)1.13547396
131Abnormality of monocarboxylic acid metabolism (HP:0010996)1.11447794
132Tubulointerstitial abnormality (HP:0001969)1.10648841
133Hyponatremia (HP:0002902)1.09579415
134Purpura (HP:0000979)1.07650148
135Stage 5 chronic kidney disease (HP:0003774)1.06728586
136Short femoral neck (HP:0100864)1.05150696
137Hypokalemic alkalosis (HP:0001949)1.05111633
138Bifid scrotum (HP:0000048)1.04021748
139Recurrent pneumonia (HP:0006532)1.03680730
140Aplasia/Hypoplasia involving the femoral head and neck (HP:0009108)1.02720020
141Fetal akinesia sequence (HP:0001989)1.00849221
142Lip pit (HP:0100267)1.00526334
143Elevated erythrocyte sedimentation rate (HP:0003565)0.99796849
144Stridor (HP:0010307)0.95425106
145Spinal muscular atrophy (HP:0007269)0.95208522
146Poor coordination (HP:0002370)0.93914574
147Abnormal drinking behavior (HP:0030082)0.92403924
148Polydipsia (HP:0001959)0.92403924

Predicted kinase interactions (KEA)

RankGene SetZ-score
1PASK9.87872419
2PNCK4.94050218
3CAMKK14.78330121
4MAPK154.63604754
5RIPK42.75597216
6SMG12.42611184
7WEE12.32320070
8CSK2.26649790
9MAP3K32.14933234
10SCYL22.12691949
11NME12.02414645
12PKN21.99720551
13DDR21.97150337
14ERBB31.95553482
15PAK41.94318495
16EPHB11.92136612
17MAP3K21.87307186
18LATS21.68693735
19MAPKAPK31.67142049
20SIK11.61173329
21STK241.56290354
22PTK2B1.48174062
23BCR1.44168838
24LATS11.41082245
25MAP3K71.40456142
26BLK1.38688136
27GRK11.37939379
28TRIB31.37286490
29MARK21.35279061
30SIK31.33876829
31MAP2K21.26014211
32TBK11.17290253
33TYK21.12950382
34ERBB21.10021041
35EPHB21.10007482
36KSR11.07121654
37GRK61.03491662
38PLK21.03000696
39PAK21.00109939
40ZAP700.99284664
41ROCK20.91184343
42VRK10.90923760
43MAP3K100.88795561
44RIPK10.86228356
45PDPK10.84120421
46NEK60.83621295
47MAPK130.83027340
48PAK60.78356875
49MST40.77054572
50PTK60.71915101
51MST1R0.71783422
52PDGFRA0.71712729
53EPHA20.71063906
54TAOK10.70913761
55TNK20.70876023
56MINK10.70660778
57HIPK20.69965036
58FLT30.69781378
59EPHA30.69270635
60RPS6KA20.69010835
61MAP2K10.68992126
62DYRK1B0.68208863
63FES0.67738601
64ROCK10.64708862
65TLK10.64222769
66TESK20.64013534
67RPS6KA40.62981656
68NTRK20.62650574
69PRKCQ0.62549146
70FER0.62216955
71NTRK30.61815078
72BTK0.61760528
73FGFR30.59659747
74ERN10.57535626
75EEF2K0.56006192
76MAP2K30.53962918
77PDK10.53193923
78CDC42BPA0.52405363
79HCK0.52318972
80DMPK0.51751009
81STK100.51112882
82PRKAA20.50776128
83MARK10.50498922
84IRAK10.50131838
85CSNK1G10.49690471
86MAP3K110.49442640
87PTK20.49000856
88BRSK20.48710488
89FGFR10.48693382
90LMTK20.46770427
91DAPK20.46731231
92INSRR0.45736855
93PLK30.45467398
94SGK10.45348750
95PRKD20.44707345
96NTRK10.44455778
97PRKCZ0.44248512
98UHMK10.43634895
99MATK0.43132503
100DYRK1A0.42553104
101PRKCD0.42336406
102AURKA0.41831480
103RET0.41586684
104TTN0.41074069
105DYRK30.40292654
106PRKCG0.40093064
107TESK10.40074073
108STK38L0.39988709
109FGFR20.39958110
110BMPR20.39083842
111CAMK1G0.37822617
112PAK30.37491073
113MAPK70.37459552
114MAP4K10.37263300
115RPS6KL10.37006937
116RPS6KC10.37006937
117ALK0.36943893
118LYN0.36879114
119CSNK1E0.36392201
120CDK60.35994644
121NLK0.35582471
122MAP3K130.34900221
123ITK0.33767057
124PRKCI0.32861856
125BRSK10.32727999
126SIK20.31424110
127MELK0.31366054
128ABL10.30148408
129CDK120.29701484
130FGFR40.29537914
131GSK3A0.29208681
132CDK140.29120187
133LRRK20.29059983
134IKBKE0.29021808
135STK110.28595844
136TRPM70.28402013
137JAK10.28063819
138ICK0.27299607
139LIMK10.26733126
140MAPK120.26619241
141CDC70.26550902
142MAP3K40.26069697
143YES10.25482956
144TTK0.25240857
145SRC0.24997215
146TYRO30.24623428
147CSNK1A1L0.24577611
148CDK180.23885900
149MAPK100.23359789
150TEC0.22510236
151EGFR0.22435745
152NEK90.22281570
153LCK0.22209887
154TGFBR20.21929834
155CSF1R0.21928744
156FYN0.21883817
157AKT20.21859329
158RPS6KA60.21656800
159MAPK90.21617670
160FGR0.21194159
161SGK20.19872525
162PRKDC0.19600433
163SGK30.18704221
164MAP3K10.18453785
165SGK2230.18431293
166SGK4940.18431293
167CDK150.18199700
168STK380.17942646
169IRAK40.17890006
170MYLK0.17385325
171MAP3K140.17196788

Predicted pathways (KEGG)

RankGene SetZ-score
1Phenylalanine metabolism_Homo sapiens_hsa003604.16933902
2Chemical carcinogenesis_Homo sapiens_hsa052043.85916367
3Dorso-ventral axis formation_Homo sapiens_hsa043203.40022730
4Hedgehog signaling pathway_Homo sapiens_hsa043403.32769274
5Synthesis and degradation of ketone bodies_Homo sapiens_hsa000723.25357025
6Basal cell carcinoma_Homo sapiens_hsa052173.22272151
7Tyrosine metabolism_Homo sapiens_hsa003503.14149949
8Hippo signaling pathway_Homo sapiens_hsa043902.50028175
9beta-Alanine metabolism_Homo sapiens_hsa004102.46348204
10ECM-receptor interaction_Homo sapiens_hsa045122.36059008
11Vasopressin-regulated water reabsorption_Homo sapiens_hsa049622.03784632
12Retinol metabolism_Homo sapiens_hsa008301.92601108
13Axon guidance_Homo sapiens_hsa043601.90860176
14Caffeine metabolism_Homo sapiens_hsa002321.81530549
15Gastric acid secretion_Homo sapiens_hsa049711.74896247
16Tight junction_Homo sapiens_hsa045301.69607058
17Linoleic acid metabolism_Homo sapiens_hsa005911.67779490
18Wnt signaling pathway_Homo sapiens_hsa043101.63658323
19ABC transporters_Homo sapiens_hsa020101.60771534
20Notch signaling pathway_Homo sapiens_hsa043301.58140524
21Nicotine addiction_Homo sapiens_hsa050331.56242402
22Focal adhesion_Homo sapiens_hsa045101.55814076
23Olfactory transduction_Homo sapiens_hsa047401.54931015
24Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.54190495
25Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.49892451
26Protein digestion and absorption_Homo sapiens_hsa049741.49454425
27Sphingolipid metabolism_Homo sapiens_hsa006001.48274226
28MicroRNAs in cancer_Homo sapiens_hsa052061.42277554
29Melanogenesis_Homo sapiens_hsa049161.41730523
30Gap junction_Homo sapiens_hsa045401.38059703
31Proteoglycans in cancer_Homo sapiens_hsa052051.34188445
32GnRH signaling pathway_Homo sapiens_hsa049121.33266676
33Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.32940372
34Estrogen signaling pathway_Homo sapiens_hsa049151.32362411
35Carbohydrate digestion and absorption_Homo sapiens_hsa049731.31838275
36Ovarian steroidogenesis_Homo sapiens_hsa049131.29760534
37Bladder cancer_Homo sapiens_hsa052191.17369193
38Sulfur metabolism_Homo sapiens_hsa009201.17239771
39Hematopoietic cell lineage_Homo sapiens_hsa046401.15696804
40Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.15540370
41Steroid hormone biosynthesis_Homo sapiens_hsa001401.14211057
42Pathways in cancer_Homo sapiens_hsa052001.12975557
43Staphylococcus aureus infection_Homo sapiens_hsa051501.11129169
44Circadian entrainment_Homo sapiens_hsa047131.10517952
45Leukocyte transendothelial migration_Homo sapiens_hsa046701.07579480
46Amphetamine addiction_Homo sapiens_hsa050311.07516860
47Colorectal cancer_Homo sapiens_hsa052101.05795334
48Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.04815640
49Graft-versus-host disease_Homo sapiens_hsa053321.03754688
50Arachidonic acid metabolism_Homo sapiens_hsa005901.03717705
51Choline metabolism in cancer_Homo sapiens_hsa052311.03091356
52Arginine and proline metabolism_Homo sapiens_hsa003301.01162748
53Small cell lung cancer_Homo sapiens_hsa052220.99810595
54Prion diseases_Homo sapiens_hsa050200.99303658
55Complement and coagulation cascades_Homo sapiens_hsa046100.98789407
56Salivary secretion_Homo sapiens_hsa049700.98537623
57Amoebiasis_Homo sapiens_hsa051460.98386726
58Cocaine addiction_Homo sapiens_hsa050300.97447432
59Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.97407269
60cAMP signaling pathway_Homo sapiens_hsa040240.96755913
61Allograft rejection_Homo sapiens_hsa053300.95923045
62Renal cell carcinoma_Homo sapiens_hsa052110.95752456
63Oxytocin signaling pathway_Homo sapiens_hsa049210.95289306
64GABAergic synapse_Homo sapiens_hsa047270.93544144
65Butanoate metabolism_Homo sapiens_hsa006500.92073041
66Hepatitis C_Homo sapiens_hsa051600.91950254
67Glioma_Homo sapiens_hsa052140.89457112
68Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.89364214
69Autoimmune thyroid disease_Homo sapiens_hsa053200.87889876
70Starch and sucrose metabolism_Homo sapiens_hsa005000.87575477
71Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.87211405
72Glycosaminoglycan degradation_Homo sapiens_hsa005310.86634792
73Thyroid hormone synthesis_Homo sapiens_hsa049180.85974395
74Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.85212865
75Glutamatergic synapse_Homo sapiens_hsa047240.83936666
76Dilated cardiomyopathy_Homo sapiens_hsa054140.83894927
77Lysine degradation_Homo sapiens_hsa003100.83343517
78Type I diabetes mellitus_Homo sapiens_hsa049400.83323301
79Prostate cancer_Homo sapiens_hsa052150.83294270
80PI3K-Akt signaling pathway_Homo sapiens_hsa041510.82407929
81Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.82199041
82Glycerophospholipid metabolism_Homo sapiens_hsa005640.81490247
83Melanoma_Homo sapiens_hsa052180.81201573
84AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.80865099
85Huntingtons disease_Homo sapiens_hsa050160.80669491
86Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.80596141
87Alcoholism_Homo sapiens_hsa050340.80445464
88Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.80280134
89Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.79741512
90Fatty acid degradation_Homo sapiens_hsa000710.78980219
91Glutathione metabolism_Homo sapiens_hsa004800.78332291
92HTLV-I infection_Homo sapiens_hsa051660.78273560
93Thyroid hormone signaling pathway_Homo sapiens_hsa049190.77773806
94Retrograde endocannabinoid signaling_Homo sapiens_hsa047230.74889371
95Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.74049473
96Adherens junction_Homo sapiens_hsa045200.71751506
97Dopaminergic synapse_Homo sapiens_hsa047280.71627450
98Central carbon metabolism in cancer_Homo sapiens_hsa052300.71598923
99Drug metabolism - other enzymes_Homo sapiens_hsa009830.71229834
100cGMP-PKG signaling pathway_Homo sapiens_hsa040220.70206552
101AMPK signaling pathway_Homo sapiens_hsa041520.68269978
102Ascorbate and aldarate metabolism_Homo sapiens_hsa000530.67742100
103Leishmaniasis_Homo sapiens_hsa051400.66868376
104Antigen processing and presentation_Homo sapiens_hsa046120.64927012
105Peroxisome_Homo sapiens_hsa041460.64738224
106Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009800.64494411
107Bile secretion_Homo sapiens_hsa049760.64277222
108Intestinal immune network for IgA production_Homo sapiens_hsa046720.63345896
109Aldosterone synthesis and secretion_Homo sapiens_hsa049250.62072509
110Taste transduction_Homo sapiens_hsa047420.61946783
111Rap1 signaling pathway_Homo sapiens_hsa040150.61335048
112TGF-beta signaling pathway_Homo sapiens_hsa043500.61042996
113Endometrial cancer_Homo sapiens_hsa052130.60871997
114Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.60017780
115Lysosome_Homo sapiens_hsa041420.59191291
116Asthma_Homo sapiens_hsa053100.58658327
117Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.58310999
118Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.58258970
119Calcium signaling pathway_Homo sapiens_hsa040200.56155290
120Circadian rhythm_Homo sapiens_hsa047100.56066077
121Other glycan degradation_Homo sapiens_hsa005110.55860870
122Histidine metabolism_Homo sapiens_hsa003400.55520321
123Jak-STAT signaling pathway_Homo sapiens_hsa046300.55229130
124Viral carcinogenesis_Homo sapiens_hsa052030.55180575
125Osteoclast differentiation_Homo sapiens_hsa043800.54785317
126Systemic lupus erythematosus_Homo sapiens_hsa053220.54286490
127Phototransduction_Homo sapiens_hsa047440.54259464
128Tuberculosis_Homo sapiens_hsa051520.53797797
129Phagosome_Homo sapiens_hsa041450.53249700
130Insulin secretion_Homo sapiens_hsa049110.52867893
131Insulin resistance_Homo sapiens_hsa049310.52685060
132Transcriptional misregulation in cancer_Homo sapiens_hsa052020.52524198
133Vitamin B6 metabolism_Homo sapiens_hsa007500.52037071
134Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.51803784
135Glucagon signaling pathway_Homo sapiens_hsa049220.51247760
136Cell cycle_Homo sapiens_hsa041100.51236370
137Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.51174901
138Regulation of actin cytoskeleton_Homo sapiens_hsa048100.51100825
139PPAR signaling pathway_Homo sapiens_hsa033200.50655282
140Pancreatic cancer_Homo sapiens_hsa052120.50075759
141Phosphatidylinositol signaling system_Homo sapiens_hsa040700.49676323
142Viral myocarditis_Homo sapiens_hsa054160.49622361
143ErbB signaling pathway_Homo sapiens_hsa040120.48921880
144Morphine addiction_Homo sapiens_hsa050320.47157473
145Long-term potentiation_Homo sapiens_hsa047200.46404621
146RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.46228043
147Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.45629666
148Vascular smooth muscle contraction_Homo sapiens_hsa042700.45282694
149Drug metabolism - cytochrome P450_Homo sapiens_hsa009820.44730885
150Sphingolipid signaling pathway_Homo sapiens_hsa040710.44332113
151Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.43126246
152Malaria_Homo sapiens_hsa051440.42903061
153Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.42469896
154Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.41738243
155Ras signaling pathway_Homo sapiens_hsa040140.41456992
156Influenza A_Homo sapiens_hsa051640.41132002
157B cell receptor signaling pathway_Homo sapiens_hsa046620.40011017
158Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.36951214
159Cyanoamino acid metabolism_Homo sapiens_hsa004600.36764534
160Pentose and glucuronate interconversions_Homo sapiens_hsa000400.36435870
161Toxoplasmosis_Homo sapiens_hsa051450.35810511
162TNF signaling pathway_Homo sapiens_hsa046680.34435773
163Glycerolipid metabolism_Homo sapiens_hsa005610.33737190
164Toll-like receptor signaling pathway_Homo sapiens_hsa046200.32775412
165Apoptosis_Homo sapiens_hsa042100.29590881
166Endocytosis_Homo sapiens_hsa041440.29483786
167Chemokine signaling pathway_Homo sapiens_hsa040620.27862609
168Acute myeloid leukemia_Homo sapiens_hsa052210.25119772
169Pancreatic secretion_Homo sapiens_hsa049720.24939779
170Measles_Homo sapiens_hsa051620.24351995
171Phospholipase D signaling pathway_Homo sapiens_hsa040720.24136136
172Legionellosis_Homo sapiens_hsa051340.23809292
173Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.23580215
174Pertussis_Homo sapiens_hsa051330.23430139
175Collecting duct acid secretion_Homo sapiens_hsa049660.23367528
176Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.23105680
177Serotonergic synapse_Homo sapiens_hsa047260.21695074
178Rheumatoid arthritis_Homo sapiens_hsa053230.21639758

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