

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | mitochondrial ATP synthesis coupled proton transport (GO:0042776) | 6.14353261 |
| 2 | chaperone-mediated protein transport (GO:0072321) | 5.92807520 |
| 3 | energy coupled proton transport, down electrochemical gradient (GO:0015985) | 5.32837284 |
| 4 | ATP synthesis coupled proton transport (GO:0015986) | 5.32837284 |
| 5 | rRNA modification (GO:0000154) | 5.14085565 |
| 6 | establishment of protein localization to mitochondrial membrane (GO:0090151) | 5.09414050 |
| 7 | regulation of mitotic spindle checkpoint (GO:1903504) | 4.82396389 |
| 8 | regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266) | 4.82396389 |
| 9 | proteasome assembly (GO:0043248) | 4.76521116 |
| 10 | spliceosomal snRNP assembly (GO:0000387) | 4.73054287 |
| 11 | somatic diversification of immune receptors via somatic mutation (GO:0002566) | 4.72940073 |
| 12 | somatic hypermutation of immunoglobulin genes (GO:0016446) | 4.72940073 |
| 13 | mitochondrial electron transport, NADH to ubiquinone (GO:0006120) | 4.72620328 |
| 14 | pseudouridine synthesis (GO:0001522) | 4.64321078 |
| 15 | establishment of integrated proviral latency (GO:0075713) | 4.43579185 |
| 16 | respiratory electron transport chain (GO:0022904) | 4.41133488 |
| 17 | electron transport chain (GO:0022900) | 4.30232313 |
| 18 | protein neddylation (GO:0045116) | 4.29334994 |
| 19 | nuclear-transcribed mRNA catabolic process, exonucleolytic (GO:0000291) | 4.20158896 |
| 20 | ribosomal small subunit assembly (GO:0000028) | 4.17319846 |
| 21 | rRNA methylation (GO:0031167) | 4.07349349 |
| 22 | RNA splicing, via endonucleolytic cleavage and ligation (GO:0000394) | 4.06277369 |
| 23 | tRNA splicing, via endonucleolytic cleavage and ligation (GO:0006388) | 4.06277369 |
| 24 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | 4.06159229 |
| 25 | nucleobase biosynthetic process (GO:0046112) | 4.03954745 |
| 26 | protein complex biogenesis (GO:0070271) | 3.84730329 |
| 27 | NADH dehydrogenase complex assembly (GO:0010257) | 3.84613138 |
| 28 | mitochondrial respiratory chain complex I biogenesis (GO:0097031) | 3.84613138 |
| 29 | mitochondrial respiratory chain complex I assembly (GO:0032981) | 3.84613138 |
| 30 | DNA deamination (GO:0045006) | 3.75774271 |
| 31 | ribosomal small subunit biogenesis (GO:0042274) | 3.73252954 |
| 32 | purine nucleobase biosynthetic process (GO:0009113) | 3.63509762 |
| 33 | mitochondrial respiratory chain complex assembly (GO:0033108) | 3.61432672 |
| 34 | viral transcription (GO:0019083) | 3.59803827 |
| 35 | negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436) | 3.59519053 |
| 36 | transcription elongation from RNA polymerase III promoter (GO:0006385) | 3.59197896 |
| 37 | termination of RNA polymerase III transcription (GO:0006386) | 3.59197896 |
| 38 | oxidative phosphorylation (GO:0006119) | 3.58007577 |
| 39 | IMP biosynthetic process (GO:0006188) | 3.57309236 |
| 40 | regulation of nuclear cell cycle DNA replication (GO:0033262) | 3.55387333 |
| 41 | translational termination (GO:0006415) | 3.49132713 |
| 42 | regulation of helicase activity (GO:0051095) | 3.47050755 |
| 43 | branched-chain amino acid catabolic process (GO:0009083) | 3.45608155 |
| 44 | IMP metabolic process (GO:0046040) | 3.42148058 |
| 45 | maturation of SSU-rRNA (GO:0030490) | 3.41051265 |
| 46 | mitochondrial RNA metabolic process (GO:0000959) | 3.38791160 |
| 47 | mannosylation (GO:0097502) | 3.33721814 |
| 48 | ribosome biogenesis (GO:0042254) | 3.33326380 |
| 49 | respiratory chain complex IV assembly (GO:0008535) | 3.32862979 |
| 50 | ribonucleoprotein complex biogenesis (GO:0022613) | 3.30867054 |
| 51 | negative regulation of ligase activity (GO:0051352) | 3.28628422 |
| 52 | negative regulation of ubiquitin-protein transferase activity (GO:0051444) | 3.28628422 |
| 53 | DNA replication checkpoint (GO:0000076) | 3.27074169 |
| 54 | cellular component biogenesis (GO:0044085) | 3.24824934 |
| 55 | ubiquinone biosynthetic process (GO:0006744) | 3.23675503 |
| 56 | chromatin remodeling at centromere (GO:0031055) | 3.23266888 |
| 57 | rRNA processing (GO:0006364) | 3.22087567 |
| 58 | translation (GO:0006412) | 3.21439605 |
| 59 | translational elongation (GO:0006414) | 3.21277684 |
| 60 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.20131479 |
| 61 | regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439) | 3.19871755 |
| 62 | regulation of cellular amino acid metabolic process (GO:0006521) | 3.19863876 |
| 63 | establishment of viral latency (GO:0019043) | 3.18597214 |
| 64 | histone mRNA metabolic process (GO:0008334) | 3.16945272 |
| 65 | branched-chain amino acid metabolic process (GO:0009081) | 3.14268610 |
| 66 | inner mitochondrial membrane organization (GO:0007007) | 3.13386081 |
| 67 | rRNA metabolic process (GO:0016072) | 3.12000220 |
| 68 | SRP-dependent cotranslational protein targeting to membrane (GO:0006614) | 3.09446257 |
| 69 | protein-cofactor linkage (GO:0018065) | 3.07837576 |
| 70 | positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051437) | 3.05440868 |
| 71 | ATP biosynthetic process (GO:0006754) | 3.04887896 |
| 72 | ribosomal large subunit biogenesis (GO:0042273) | 3.04843995 |
| 73 | cotranslational protein targeting to membrane (GO:0006613) | 3.04092295 |
| 74 | CENP-A containing nucleosome assembly (GO:0034080) | 3.03686354 |
| 75 | cytochrome complex assembly (GO:0017004) | 3.02934581 |
| 76 | serine family amino acid catabolic process (GO:0009071) | 3.02243629 |
| 77 | protein targeting to ER (GO:0045047) | 3.01983919 |
| 78 | DNA damage response, detection of DNA damage (GO:0042769) | 2.94879692 |
| 79 | DNA ligation (GO:0006266) | 2.92612899 |
| 80 | termination of RNA polymerase II transcription (GO:0006369) | 2.90738543 |
| 81 | signal transduction involved in mitotic cell cycle checkpoint (GO:0072413) | 2.90735561 |
| 82 | signal transduction involved in mitotic DNA integrity checkpoint (GO:1902403) | 2.90735561 |
| 83 | signal transduction involved in mitotic DNA damage checkpoint (GO:1902402) | 2.90735561 |
| 84 | aerobic respiration (GO:0009060) | 2.90433134 |
| 85 | peptidyl-arginine omega-N-methylation (GO:0035247) | 2.89353522 |
| 86 | translational initiation (GO:0006413) | 2.87642614 |
| 87 | hydrogen ion transmembrane transport (GO:1902600) | 2.87218212 |
| 88 | protein targeting to mitochondrion (GO:0006626) | 2.86563158 |
| 89 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest (GO:00 | 2.86506127 |
| 90 | establishment of protein localization to endoplasmic reticulum (GO:0072599) | 2.85170340 |
| 91 | DNA replication-dependent nucleosome assembly (GO:0006335) | 2.84402361 |
| 92 | DNA replication-dependent nucleosome organization (GO:0034723) | 2.84402361 |
| 93 | anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:0 | 2.82953044 |
| 94 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay (GO:0000184) | 2.82134468 |
| 95 | signal transduction involved in mitotic G1 DNA damage checkpoint (GO:0072431) | 2.81342231 |
| 96 | intracellular signal transduction involved in G1 DNA damage checkpoint (GO:1902400) | 2.81342231 |
| 97 | ubiquinone metabolic process (GO:0006743) | 2.80723791 |
| 98 | regulation of mitochondrial translation (GO:0070129) | 2.80659844 |
| 99 | signal transduction involved in DNA damage checkpoint (GO:0072422) | 2.80579274 |
| 100 | signal transduction involved in DNA integrity checkpoint (GO:0072401) | 2.80579274 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human | 6.00079299 |
| 2 | GABP_17652178_ChIP-ChIP_JURKAT_Human | 4.10118781 |
| 3 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 3.93652728 |
| 4 | EST1_17652178_ChIP-ChIP_JURKAT_Human | 3.84046210 |
| 5 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 3.80195215 |
| 6 | E2F7_22180533_ChIP-Seq_HELA_Human | 3.60168383 |
| 7 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.54904792 |
| 8 | JARID1A_20064375_ChIP-Seq_MESCs_Mouse | 3.43462794 |
| 9 | NOTCH1_17114293_ChIP-ChIP_T-ALL_Human | 3.17975135 |
| 10 | ETS1_20019798_ChIP-Seq_JURKAT_Human | 3.15278659 |
| 11 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 3.13785687 |
| 12 | MYCN_21190229_ChIP-Seq_SHEP-21N_Human | 3.08716244 |
| 13 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 3.03383250 |
| 14 | CREB1_15753290_ChIP-ChIP_HEK293T_Human | 2.89468710 |
| 15 | CHD1_19587682_ChIP-ChIP_MESCs_Mouse | 2.88049778 |
| 16 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 2.75903083 |
| 17 | E2F4_17652178_ChIP-ChIP_JURKAT_Human | 2.62295480 |
| 18 | HCFC1_20581084_ChIP-Seq_MESCs_Mouse | 2.61714787 |
| 19 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.58268329 |
| 20 | FOXP3_21729870_ChIP-Seq_TREG_Human | 2.55114964 |
| 21 | VDR_23849224_ChIP-Seq_CD4+_Human | 2.46747996 |
| 22 | ELK1_19687146_ChIP-ChIP_HELA_Human | 2.43593086 |
| 23 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 2.41271510 |
| 24 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 2.41020176 |
| 25 | MYC_19079543_ChIP-ChIP_MESCs_Mouse | 2.25922297 |
| 26 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.17113791 |
| 27 | PDX1_19855005_ChIP-ChIP_MIN6_Mouse | 2.04700641 |
| 28 | THAP11_20581084_ChIP-Seq_MESCs_Mouse | 1.94191758 |
| 29 | YY1_21170310_ChIP-Seq_MESCs_Mouse | 1.90095028 |
| 30 | YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.88573193 |
| 31 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.85777707 |
| 32 | HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse | 1.85001467 |
| 33 | TTF2_22483619_ChIP-Seq_HELA_Human | 1.79932813 |
| 34 | XRN2_22483619_ChIP-Seq_HELA_Human | 1.76654764 |
| 35 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 1.75159697 |
| 36 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.72207034 |
| 37 | FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse | 1.67728818 |
| 38 | ZNF274_21170338_ChIP-Seq_K562_Hela | 1.63496090 |
| 39 | FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human | 1.56153437 |
| 40 | MYC_18940864_ChIP-ChIP_HL60_Human | 1.55003760 |
| 41 | DCP1A_22483619_ChIP-Seq_HELA_Human | 1.53445967 |
| 42 | GABP_19822575_ChIP-Seq_HepG2_Human | 1.50278143 |
| 43 | NELFA_20434984_ChIP-Seq_ESCs_Mouse | 1.48688373 |
| 44 | CIITA_25753668_ChIP-Seq_RAJI_Human | 1.46422301 |
| 45 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 1.44949350 |
| 46 | ZFP42_18358816_ChIP-ChIP_MESCs_Mouse | 1.43239297 |
| 47 | MYBL2_22936984_ChIP-ChIP_MESCs_Mouse | 1.41048954 |
| 48 | PADI4_21655091_ChIP-ChIP_MCF-7_Human | 1.36864977 |
| 49 | POU5F1_16153702_ChIP-ChIP_HESCs_Human | 1.36431599 |
| 50 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 1.32814208 |
| 51 | EWS_26573619_Chip-Seq_HEK293_Human | 1.30911423 |
| 52 | POU5F1_18358816_ChIP-ChIP_MESCs_Mouse | 1.27392810 |
| 53 | PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.24892838 |
| 54 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 1.20301609 |
| 55 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.19598913 |
| 56 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.19236261 |
| 57 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.17612940 |
| 58 | DMRT1_21621532_ChIP-ChIP_FETAL_Ovary | 1.17171443 |
| 59 | FUS_26573619_Chip-Seq_HEK293_Human | 1.13103012 |
| 60 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 1.12146915 |
| 61 | VDR_22108803_ChIP-Seq_LS180_Human | 1.12146508 |
| 62 | SOX2_16153702_ChIP-ChIP_HESCs_Human | 1.10081366 |
| 63 | E2F1_21310950_ChIP-Seq_MCF-7_Human | 1.05049191 |
| 64 | SOX2_18555785_ChIP-Seq_MESCs_Mouse | 1.04554860 |
| 65 | POU5F1_18555785_ChIP-Seq_MESCs_Mouse | 1.04313134 |
| 66 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 1.02813673 |
| 67 | KDM5A_27292631_Chip-Seq_BREAST_Human | 1.01655172 |
| 68 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 1.01469994 |
| 69 | YY1_22570637_ChIP-Seq_MALME-3M_Human | 0.99358430 |
| 70 | MYCN_18555785_ChIP-Seq_MESCs_Mouse | 0.98646925 |
| 71 | EBNA2_21746931_ChIP-Seq_IB4-LCL_Human | 0.95441311 |
| 72 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 0.95109202 |
| 73 | ASH2L_23239880_ChIP-Seq_MESCs_Mouse | 0.94670397 |
| 74 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.89295737 |
| 75 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 0.89130802 |
| 76 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 0.87197160 |
| 77 | RBPJ_21746931_ChIP-Seq_IB4-LCL_Human | 0.86783218 |
| 78 | KLF4_19030024_ChIP-ChIP_MESCs_Mouse | 0.86469884 |
| 79 | ELK1_22589737_ChIP-Seq_MCF10A_Human | 0.86226729 |
| 80 | E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human | 0.85137668 |
| 81 | IGF1R_20145208_ChIP-Seq_DFB_Human | 0.85030873 |
| 82 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 0.85024866 |
| 83 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 0.85024866 |
| 84 | NANOG_18555785_ChIP-Seq_MESCs_Mouse | 0.83497203 |
| 85 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.83054227 |
| 86 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 0.82888727 |
| 87 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 0.82592103 |
| 88 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 0.82558167 |
| 89 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.81237584 |
| 90 | FLI1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 0.78673730 |
| 91 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.77904839 |
| 92 | RBPJ_21746931_ChIP-Seq_IB4_Human | 0.76980408 |
| 93 | GATA1_26923725_Chip-Seq_HPCs_Mouse | 0.76536763 |
| 94 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 0.76419642 |
| 95 | TP53_22573176_ChIP-Seq_HFKS_Human | 0.74261605 |
| 96 | AR_20517297_ChIP-Seq_VCAP_Human | 0.73538160 |
| 97 | CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.71392879 |
| 98 | GATA6_21074721_ChIP-Seq_CACO-2_Human | 0.69957991 |
| 99 | IRF1_19129219_ChIP-ChIP_H3396_Human | 0.69529228 |
| 100 | KLF4_18264089_ChIP-ChIP_MESCs_Mouse | 0.69009563 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003787_abnormal_imprinting | 4.68418269 |
| 2 | MP0008058_abnormal_DNA_repair | 4.21042650 |
| 3 | MP0003123_paternal_imprinting | 3.16228954 |
| 4 | MP0003693_abnormal_embryo_hatching | 3.14926034 |
| 5 | MP0003195_calcinosis | 3.03448710 |
| 6 | MP0003718_maternal_effect | 2.96316816 |
| 7 | MP0004957_abnormal_blastocyst_morpholog | 2.80760518 |
| 8 | MP0003111_abnormal_nucleus_morphology | 2.78450908 |
| 9 | MP0005646_abnormal_pituitary_gland | 2.57091813 |
| 10 | MP0003941_abnormal_skin_development | 2.52269026 |
| 11 | MP0010094_abnormal_chromosome_stability | 2.50914397 |
| 12 | MP0001764_abnormal_homeostasis | 2.42566478 |
| 13 | MP0008007_abnormal_cellular_replicative | 2.23205967 |
| 14 | MP0003121_genomic_imprinting | 2.16240668 |
| 15 | MP0008877_abnormal_DNA_methylation | 2.12944941 |
| 16 | MP0009379_abnormal_foot_pigmentation | 2.12302634 |
| 17 | MP0010368_abnormal_lymphatic_system | 2.08586045 |
| 18 | MP0006292_abnormal_olfactory_placode | 2.04163854 |
| 19 | MP0002254_reproductive_system_inflammat | 1.92015646 |
| 20 | MP0009697_abnormal_copulation | 1.85515635 |
| 21 | MP0008875_abnormal_xenobiotic_pharmacok | 1.84345495 |
| 22 | MP0002277_abnormal_respiratory_mucosa | 1.83451371 |
| 23 | MP0006036_abnormal_mitochondrial_physio | 1.82942201 |
| 24 | MP0003724_increased_susceptibility_to | 1.81722191 |
| 25 | MP0003186_abnormal_redox_activity | 1.75106618 |
| 26 | MP0003786_premature_aging | 1.71414599 |
| 27 | MP0000372_irregular_coat_pigmentation | 1.70309723 |
| 28 | MP0005551_abnormal_eye_electrophysiolog | 1.68175916 |
| 29 | MP0008932_abnormal_embryonic_tissue | 1.64902686 |
| 30 | MP0005645_abnormal_hypothalamus_physiol | 1.61098336 |
| 31 | MP0005075_abnormal_melanosome_morpholog | 1.59420325 |
| 32 | MP0004147_increased_porphyrin_level | 1.55243615 |
| 33 | MP0003806_abnormal_nucleotide_metabolis | 1.44212924 |
| 34 | MP0002735_abnormal_chemical_nociception | 1.39019135 |
| 35 | MP0006072_abnormal_retinal_apoptosis | 1.38904510 |
| 36 | MP0002736_abnormal_nociception_after | 1.36880343 |
| 37 | MP0003077_abnormal_cell_cycle | 1.33412199 |
| 38 | MP0002837_dystrophic_cardiac_calcinosis | 1.32710049 |
| 39 | MP0001968_abnormal_touch/_nociception | 1.31676114 |
| 40 | MP0002148_abnormal_hypersensitivity_rea | 1.30554858 |
| 41 | MP0001293_anophthalmia | 1.26925202 |
| 42 | MP0008872_abnormal_physiological_respon | 1.26757350 |
| 43 | MP0006035_abnormal_mitochondrial_morpho | 1.25297485 |
| 44 | MP0008995_early_reproductive_senescence | 1.24183268 |
| 45 | MP0001529_abnormal_vocalization | 1.20752752 |
| 46 | MP0003638_abnormal_response/metabolism_ | 1.15257374 |
| 47 | MP0005395_other_phenotype | 1.13990554 |
| 48 | MP0001905_abnormal_dopamine_level | 1.12519875 |
| 49 | MP0002396_abnormal_hematopoietic_system | 1.10263808 |
| 50 | MP0003880_abnormal_central_pattern | 1.10060799 |
| 51 | MP0010386_abnormal_urinary_bladder | 1.08631302 |
| 52 | MP0005332_abnormal_amino_acid | 1.08380896 |
| 53 | MP0003011_delayed_dark_adaptation | 1.07811454 |
| 54 | MP0008260_abnormal_autophagy | 1.05434100 |
| 55 | MP0002733_abnormal_thermal_nociception | 1.04586752 |
| 56 | MP0002282_abnormal_trachea_morphology | 1.03229759 |
| 57 | MP0001929_abnormal_gametogenesis | 1.00607088 |
| 58 | MP0002210_abnormal_sex_determination | 0.99735557 |
| 59 | MP0001485_abnormal_pinna_reflex | 0.94074483 |
| 60 | MP0002102_abnormal_ear_morphology | 0.93580211 |
| 61 | MP0002933_joint_inflammation | 0.92435718 |
| 62 | MP0000313_abnormal_cell_death | 0.90857837 |
| 63 | MP0002019_abnormal_tumor_incidence | 0.90736927 |
| 64 | MP0008873_increased_physiological_sensi | 0.90324117 |
| 65 | MP0001145_abnormal_male_reproductive | 0.87914178 |
| 66 | MP0002111_abnormal_tail_morphology | 0.86105995 |
| 67 | MP0000653_abnormal_sex_gland | 0.86038809 |
| 68 | MP0005253_abnormal_eye_physiology | 0.84624008 |
| 69 | MP0009765_abnormal_xenobiotic_induced | 0.84161221 |
| 70 | MP0005084_abnormal_gallbladder_morpholo | 0.81163953 |
| 71 | MP0000467_abnormal_esophagus_morphology | 0.80660678 |
| 72 | MP0000516_abnormal_urinary_system | 0.79696879 |
| 73 | MP0005367_renal/urinary_system_phenotyp | 0.79696879 |
| 74 | MP0001970_abnormal_pain_threshold | 0.78654160 |
| 75 | MP0009333_abnormal_splenocyte_physiolog | 0.78212146 |
| 76 | MP0001835_abnormal_antigen_presentation | 0.77202942 |
| 77 | MP0002160_abnormal_reproductive_system | 0.76845975 |
| 78 | MP0005220_abnormal_exocrine_pancreas | 0.74674624 |
| 79 | MP0006276_abnormal_autonomic_nervous | 0.74567696 |
| 80 | MP0003646_muscle_fatigue | 0.72729858 |
| 81 | MP0005636_abnormal_mineral_homeostasis | 0.72297265 |
| 82 | MP0001119_abnormal_female_reproductive | 0.72011708 |
| 83 | MP0009764_decreased_sensitivity_to | 0.71874013 |
| 84 | MP0000490_abnormal_crypts_of | 0.71243525 |
| 85 | MP0004043_abnormal_pH_regulation | 0.69436911 |
| 86 | MP0005310_abnormal_salivary_gland | 0.68511758 |
| 87 | MP0003137_abnormal_impulse_conducting | 0.67188574 |
| 88 | MP0003567_abnormal_fetal_cardiomyocyte | 0.67069280 |
| 89 | MP0002822_catalepsy | 0.66697347 |
| 90 | MP0001730_embryonic_growth_arrest | 0.66522619 |
| 91 | MP0003698_abnormal_male_reproductive | 0.65057514 |
| 92 | MP0000350_abnormal_cell_proliferation | 0.63710273 |
| 93 | MP0005389_reproductive_system_phenotype | 0.60957947 |
| 94 | MP0002938_white_spotting | 0.59813768 |
| 95 | MP0005000_abnormal_immune_tolerance | 0.59361916 |
| 96 | MP0000689_abnormal_spleen_morphology | 0.57435224 |
| 97 | MP0002398_abnormal_bone_marrow | 0.57209935 |
| 98 | MP0003866_abnormal_defecation | 0.56802866 |
| 99 | MP0001881_abnormal_mammary_gland | 0.55781146 |
| 100 | MP0008775_abnormal_heart_ventricle | 0.55407943 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Acute necrotizing encephalopathy (HP:0006965) | 5.58888455 |
| 2 | Acute encephalopathy (HP:0006846) | 4.99563461 |
| 3 | Abnormal mitochondria in muscle tissue (HP:0008316) | 4.98351148 |
| 4 | Mitochondrial inheritance (HP:0001427) | 4.82722323 |
| 5 | Progressive macrocephaly (HP:0004481) | 4.61203189 |
| 6 | Increased hepatocellular lipid droplets (HP:0006565) | 4.39776369 |
| 7 | Increased CSF lactate (HP:0002490) | 4.20768753 |
| 8 | Cerebral edema (HP:0002181) | 4.12141928 |
| 9 | Hepatocellular necrosis (HP:0001404) | 3.99470289 |
| 10 | Lipid accumulation in hepatocytes (HP:0006561) | 3.91409875 |
| 11 | 3-Methylglutaconic aciduria (HP:0003535) | 3.75771808 |
| 12 | Hepatic necrosis (HP:0002605) | 3.71380972 |
| 13 | Aplastic anemia (HP:0001915) | 3.64342020 |
| 14 | Hyperglycinemia (HP:0002154) | 3.55004998 |
| 15 | Hyperglycinuria (HP:0003108) | 3.41537834 |
| 16 | Increased intramyocellular lipid droplets (HP:0012240) | 3.33138245 |
| 17 | Renal Fanconi syndrome (HP:0001994) | 3.31171947 |
| 18 | Decreased activity of cytochrome C oxidase in muscle tissue (HP:0003688) | 3.29379613 |
| 19 | Colon cancer (HP:0003003) | 3.23429413 |
| 20 | Exertional dyspnea (HP:0002875) | 3.19316165 |
| 21 | Abnormality of glycine metabolism (HP:0010895) | 3.16105487 |
| 22 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.16105487 |
| 23 | Type 2 muscle fiber atrophy (HP:0003554) | 3.06403409 |
| 24 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 3.05589330 |
| 25 | Lactic acidosis (HP:0003128) | 3.03901674 |
| 26 | Type I transferrin isoform profile (HP:0003642) | 2.99786177 |
| 27 | Panhypogammaglobulinemia (HP:0003139) | 2.95069234 |
| 28 | Attenuation of retinal blood vessels (HP:0007843) | 2.94603115 |
| 29 | Abnormal number of erythroid precursors (HP:0012131) | 2.94478167 |
| 30 | Pancreatic fibrosis (HP:0100732) | 2.89839594 |
| 31 | Pancreatic cysts (HP:0001737) | 2.89756679 |
| 32 | Lethargy (HP:0001254) | 2.83575289 |
| 33 | Congenital stationary night blindness (HP:0007642) | 2.82081576 |
| 34 | Abnormality of serum amino acid levels (HP:0003112) | 2.81057786 |
| 35 | Optic disc pallor (HP:0000543) | 2.79790142 |
| 36 | Muscle fiber atrophy (HP:0100295) | 2.76963038 |
| 37 | Increased muscle lipid content (HP:0009058) | 2.74918238 |
| 38 | Respiratory failure (HP:0002878) | 2.69349547 |
| 39 | Decreased central vision (HP:0007663) | 2.68909758 |
| 40 | Generalized aminoaciduria (HP:0002909) | 2.66701753 |
| 41 | Increased serum lactate (HP:0002151) | 2.64531401 |
| 42 | Cerebellar dysplasia (HP:0007033) | 2.63895284 |
| 43 | True hermaphroditism (HP:0010459) | 2.60701298 |
| 44 | Oral leukoplakia (HP:0002745) | 2.59876128 |
| 45 | Macrocytic anemia (HP:0001972) | 2.59406435 |
| 46 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.58384093 |
| 47 | Exercise intolerance (HP:0003546) | 2.56025250 |
| 48 | Leukodystrophy (HP:0002415) | 2.53251995 |
| 49 | Occipital encephalocele (HP:0002085) | 2.47222800 |
| 50 | Muscle abnormality related to mitochondrial dysfunction (HP:0003800) | 2.46995016 |
| 51 | Methylmalonic aciduria (HP:0012120) | 2.46614762 |
| 52 | Type II lissencephaly (HP:0007260) | 2.44800948 |
| 53 | Methylmalonic acidemia (HP:0002912) | 2.44388614 |
| 54 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 2.43097433 |
| 55 | Abnormality of alanine metabolism (HP:0010916) | 2.43097433 |
| 56 | Hyperalaninemia (HP:0003348) | 2.43097433 |
| 57 | Abnormal protein glycosylation (HP:0012346) | 2.37564454 |
| 58 | Abnormal glycosylation (HP:0012345) | 2.37564454 |
| 59 | Abnormal isoelectric focusing of serum transferrin (HP:0003160) | 2.37564454 |
| 60 | Abnormal protein N-linked glycosylation (HP:0012347) | 2.37564454 |
| 61 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 2.34170582 |
| 62 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 2.34170582 |
| 63 | Megaloblastic anemia (HP:0001889) | 2.33362723 |
| 64 | Impulsivity (HP:0100710) | 2.30246509 |
| 65 | Abnormality of the labia minora (HP:0012880) | 2.28145421 |
| 66 | Abnormality of the ileum (HP:0001549) | 2.24796976 |
| 67 | Meckel diverticulum (HP:0002245) | 2.24043795 |
| 68 | Tinnitus (HP:0000360) | 2.22950344 |
| 69 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.19729972 |
| 70 | Reduced antithrombin III activity (HP:0001976) | 2.07471215 |
| 71 | Severe visual impairment (HP:0001141) | 2.06401823 |
| 72 | Hyperphosphaturia (HP:0003109) | 2.06130845 |
| 73 | Hypothermia (HP:0002045) | 2.05305435 |
| 74 | Inability to walk (HP:0002540) | 2.04697646 |
| 75 | Hypoglycemic coma (HP:0001325) | 2.04507090 |
| 76 | Severe combined immunodeficiency (HP:0004430) | 2.03353912 |
| 77 | Respiratory difficulties (HP:0002880) | 2.03075667 |
| 78 | Abnormal rod and cone electroretinograms (HP:0008323) | 1.99749762 |
| 79 | Abnormality of urine glucose concentration (HP:0011016) | 1.96953297 |
| 80 | Glycosuria (HP:0003076) | 1.96953297 |
| 81 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 1.96906814 |
| 82 | Dicarboxylic aciduria (HP:0003215) | 1.96906814 |
| 83 | Gonadal dysgenesis (HP:0000133) | 1.96362039 |
| 84 | Renal cortical cysts (HP:0000803) | 1.88314246 |
| 85 | Ketosis (HP:0001946) | 1.87745893 |
| 86 | Ketoacidosis (HP:0001993) | 1.87689784 |
| 87 | Abnormality of methionine metabolism (HP:0010901) | 1.87514152 |
| 88 | Abnormal lung lobation (HP:0002101) | 1.87506935 |
| 89 | Nausea (HP:0002018) | 1.84910779 |
| 90 | Abolished electroretinogram (ERG) (HP:0000550) | 1.84579624 |
| 91 | Abnormality of renal resorption (HP:0011038) | 1.84317711 |
| 92 | Abnormality of the preputium (HP:0100587) | 1.82371279 |
| 93 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 1.80993880 |
| 94 | Combined immunodeficiency (HP:0005387) | 1.78235335 |
| 95 | Aplasia/Hypoplasia of the uvula (HP:0010293) | 1.75647782 |
| 96 | Pancytopenia (HP:0001876) | 1.75297164 |
| 97 | Nephronophthisis (HP:0000090) | 1.73724967 |
| 98 | Anencephaly (HP:0002323) | 1.73277280 |
| 99 | Prostate neoplasm (HP:0100787) | 1.72994597 |
| 100 | Opisthotonus (HP:0002179) | 1.71833267 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | VRK2 | 4.88801110 |
| 2 | STK16 | 4.18006875 |
| 3 | ZAK | 3.96515560 |
| 4 | CDC7 | 3.41123510 |
| 5 | NUAK1 | 3.34824947 |
| 6 | BCKDK | 3.32856341 |
| 7 | BUB1 | 3.22668690 |
| 8 | MKNK1 | 3.20503964 |
| 9 | SRPK1 | 3.01148945 |
| 10 | PLK4 | 2.86893894 |
| 11 | TAF1 | 2.46854389 |
| 12 | NME2 | 2.42065840 |
| 13 | KDR | 2.33858681 |
| 14 | PBK | 2.31046584 |
| 15 | MAPKAPK5 | 2.14028974 |
| 16 | EIF2AK3 | 2.06780329 |
| 17 | VRK1 | 2.05852251 |
| 18 | NME1 | 1.75312146 |
| 19 | MAP4K2 | 1.73683850 |
| 20 | TNK2 | 1.69384978 |
| 21 | TTK | 1.64587324 |
| 22 | TIE1 | 1.64250772 |
| 23 | ADRBK2 | 1.50955078 |
| 24 | PLK3 | 1.49898304 |
| 25 | TEC | 1.34431363 |
| 26 | NEK1 | 1.34128467 |
| 27 | TNIK | 1.32501151 |
| 28 | TESK2 | 1.23475535 |
| 29 | EIF2AK2 | 1.18425645 |
| 30 | ALK | 1.17801574 |
| 31 | TSSK6 | 1.15058726 |
| 32 | BMX | 1.13776839 |
| 33 | BMPR1B | 1.12773986 |
| 34 | FLT3 | 1.09728646 |
| 35 | GRK1 | 1.08896260 |
| 36 | TAOK3 | 1.04057943 |
| 37 | RPS6KA5 | 1.02593935 |
| 38 | TXK | 1.01766322 |
| 39 | IRAK4 | 1.00258462 |
| 40 | CDK19 | 0.97947046 |
| 41 | WNK3 | 0.96999504 |
| 42 | FES | 0.96553879 |
| 43 | PLK1 | 0.93935975 |
| 44 | TLK1 | 0.89088323 |
| 45 | EIF2AK1 | 0.83122717 |
| 46 | KIT | 0.81798662 |
| 47 | CLK1 | 0.77193716 |
| 48 | ATR | 0.74995864 |
| 49 | CHEK2 | 0.73015021 |
| 50 | ACVR1B | 0.72883183 |
| 51 | NLK | 0.71384527 |
| 52 | PRKCQ | 0.70849714 |
| 53 | AURKB | 0.70363134 |
| 54 | BRSK2 | 0.63916775 |
| 55 | DYRK2 | 0.63481015 |
| 56 | SCYL2 | 0.63318387 |
| 57 | ITK | 0.60191350 |
| 58 | MARK3 | 0.57168135 |
| 59 | CDK7 | 0.56069673 |
| 60 | ADRBK1 | 0.55521792 |
| 61 | PASK | 0.54602854 |
| 62 | OXSR1 | 0.52529402 |
| 63 | STK4 | 0.51588377 |
| 64 | MKNK2 | 0.51442677 |
| 65 | DAPK1 | 0.50479287 |
| 66 | BCR | 0.50061129 |
| 67 | TAOK2 | 0.49482756 |
| 68 | MST4 | 0.47310018 |
| 69 | PIM1 | 0.46386934 |
| 70 | PIM2 | 0.45650566 |
| 71 | CSNK2A1 | 0.44847989 |
| 72 | IRAK1 | 0.44260983 |
| 73 | CSNK2A2 | 0.43415406 |
| 74 | FRK | 0.40220875 |
| 75 | LIMK1 | 0.37744920 |
| 76 | NEK2 | 0.37389343 |
| 77 | CSNK1G1 | 0.36118242 |
| 78 | WNK4 | 0.35310058 |
| 79 | INSRR | 0.33906179 |
| 80 | SMG1 | 0.33498697 |
| 81 | ATM | 0.31753993 |
| 82 | GRK5 | 0.30449227 |
| 83 | GRK6 | 0.30003379 |
| 84 | CSF1R | 0.29757177 |
| 85 | LYN | 0.26402398 |
| 86 | BRSK1 | 0.25828321 |
| 87 | ABL2 | 0.25168668 |
| 88 | ARAF | 0.24852899 |
| 89 | PRKCI | 0.24695859 |
| 90 | CSNK1A1 | 0.23584607 |
| 91 | PRKCG | 0.22759783 |
| 92 | SYK | 0.22706020 |
| 93 | CCNB1 | 0.21552962 |
| 94 | IKBKE | 0.21304561 |
| 95 | OBSCN | 0.19210640 |
| 96 | STK24 | 0.19124143 |
| 97 | PRKDC | 0.17443187 |
| 98 | LRRK2 | 0.16881763 |
| 99 | AURKA | 0.15621816 |
| 100 | PRKCA | 0.14581365 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Proteasome_Homo sapiens_hsa03050 | 3.84709528 |
| 2 | Ribosome_Homo sapiens_hsa03010 | 3.83883807 |
| 3 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 3.30345929 |
| 4 | RNA polymerase_Homo sapiens_hsa03020 | 2.98631740 |
| 5 | Parkinsons disease_Homo sapiens_hsa05012 | 2.97693837 |
| 6 | DNA replication_Homo sapiens_hsa03030 | 2.94192718 |
| 7 | One carbon pool by folate_Homo sapiens_hsa00670 | 2.88140016 |
| 8 | Ribosome biogenesis in eukaryotes_Homo sapiens_hsa03008 | 2.79828960 |
| 9 | Mismatch repair_Homo sapiens_hsa03430 | 2.73598211 |
| 10 | Non-homologous end-joining_Homo sapiens_hsa03450 | 2.45826463 |
| 11 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 2.41077916 |
| 12 | Homologous recombination_Homo sapiens_hsa03440 | 2.14547100 |
| 13 | Spliceosome_Homo sapiens_hsa03040 | 2.06819177 |
| 14 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 1.99546065 |
| 15 | Huntingtons disease_Homo sapiens_hsa05016 | 1.99101644 |
| 16 | Base excision repair_Homo sapiens_hsa03410 | 1.88927534 |
| 17 | Protein export_Homo sapiens_hsa03060 | 1.82305855 |
| 18 | Basal transcription factors_Homo sapiens_hsa03022 | 1.75865218 |
| 19 | Alzheimers disease_Homo sapiens_hsa05010 | 1.74909990 |
| 20 | RNA degradation_Homo sapiens_hsa03018 | 1.71676314 |
| 21 | Primary immunodeficiency_Homo sapiens_hsa05340 | 1.71665453 |
| 22 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.70305213 |
| 23 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 1.70255373 |
| 24 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 1.69660879 |
| 25 | RNA transport_Homo sapiens_hsa03013 | 1.67271762 |
| 26 | Propanoate metabolism_Homo sapiens_hsa00640 | 1.62405030 |
| 27 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 1.58146280 |
| 28 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.54920514 |
| 29 | Nucleotide excision repair_Homo sapiens_hsa03420 | 1.51640378 |
| 30 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 1.47527626 |
| 31 | Phototransduction_Homo sapiens_hsa04744 | 1.34560433 |
| 32 | Purine metabolism_Homo sapiens_hsa00230 | 1.31655397 |
| 33 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.27289061 |
| 34 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 1.21375693 |
| 35 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 1.21114648 |
| 36 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.17579651 |
| 37 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.17494444 |
| 38 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 1.17233693 |
| 39 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.14620002 |
| 40 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 1.13291557 |
| 41 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.05085175 |
| 42 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.02511037 |
| 43 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.97868806 |
| 44 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.90784859 |
| 45 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 0.86428730 |
| 46 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.86378574 |
| 47 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.86288572 |
| 48 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.86032930 |
| 49 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 0.84101822 |
| 50 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 0.81941680 |
| 51 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.81328541 |
| 52 | Carbon metabolism_Homo sapiens_hsa01200 | 0.79683608 |
| 53 | Metabolic pathways_Homo sapiens_hsa01100 | 0.78537342 |
| 54 | Peroxisome_Homo sapiens_hsa04146 | 0.77554006 |
| 55 | Tryptophan metabolism_Homo sapiens_hsa00380 | 0.74434037 |
| 56 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 0.73959280 |
| 57 | Cell cycle_Homo sapiens_hsa04110 | 0.73173155 |
| 58 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 0.70885598 |
| 59 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 0.69744291 |
| 60 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 0.69566113 |
| 61 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.68486898 |
| 62 | Retinol metabolism_Homo sapiens_hsa00830 | 0.65712999 |
| 63 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.62596490 |
| 64 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.62140946 |
| 65 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 0.61997658 |
| 66 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.61756482 |
| 67 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.60657745 |
| 68 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 0.59824233 |
| 69 | Antigen processing and presentation_Homo sapiens_hsa04612 | 0.57741257 |
| 70 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 0.56153714 |
| 71 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.55243360 |
| 72 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.54202238 |
| 73 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.53385654 |
| 74 | Ether lipid metabolism_Homo sapiens_hsa00565 | 0.52930535 |
| 75 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 0.52456409 |
| 76 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.52238001 |
| 77 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 0.49367393 |
| 78 | Asthma_Homo sapiens_hsa05310 | 0.44051228 |
| 79 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 0.42235139 |
| 80 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.42126908 |
| 81 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.41312669 |
| 82 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.40575885 |
| 83 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.39238241 |
| 84 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.38322308 |
| 85 | Allograft rejection_Homo sapiens_hsa05330 | 0.37881470 |
| 86 | Taste transduction_Homo sapiens_hsa04742 | 0.37626106 |
| 87 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.36885529 |
| 88 | Olfactory transduction_Homo sapiens_hsa04740 | 0.36508483 |
| 89 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.35451320 |
| 90 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.34091633 |
| 91 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.34002511 |
| 92 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.29911467 |
| 93 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.27827032 |
| 94 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.27676439 |
| 95 | Folate biosynthesis_Homo sapiens_hsa00790 | 0.25688407 |
| 96 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.24214587 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.23002789 |
| 98 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 0.22779797 |
| 99 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.20864730 |
| 100 | Histidine metabolism_Homo sapiens_hsa00340 | 0.20812415 |

