CSGALNACT1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1blood vessel maturation (GO:0001955)5.73999078
2negative regulation of telomerase activity (GO:0051974)5.39731254
3dermatan sulfate biosynthetic process (GO:0030208)5.22887778
4regulation of neuron projection regeneration (GO:0070570)5.04485429
5regulation of axon regeneration (GO:0048679)5.04485429
6positive regulation of natural killer cell differentiation (GO:0032825)5.03019577
7definitive hemopoiesis (GO:0060216)5.00108314
8dermatan sulfate metabolic process (GO:0030205)5.00043046
9collagen fibril organization (GO:0030199)4.79620381
10mesenchymal-epithelial cell signaling (GO:0060638)4.70502935
11phospholipid scrambling (GO:0017121)4.43850941
12chondrocyte proliferation (GO:0035988)4.37906879
13* chondroitin sulfate biosynthetic process (GO:0030206)4.28623044
14response to gravity (GO:0009629)4.06987706
15sequestering of extracellular ligand from receptor (GO:0035581)3.89697066
16protein heterotrimerization (GO:0070208)3.86484714
17neuron remodeling (GO:0016322)3.75825308
18mitochondrial genome maintenance (GO:0000002)3.72435126
19positive regulation of blood vessel endothelial cell migration (GO:0043536)3.62911007
20regulation of natural killer cell differentiation (GO:0032823)3.54459412
21negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.52240973
22negative regulation of cell killing (GO:0031342)3.52240973
23interleukin-6-mediated signaling pathway (GO:0070102)3.49186394
24cartilage development involved in endochondral bone morphogenesis (GO:0060351)3.46189712
25phagocytosis, recognition (GO:0006910)3.35187424
26fibril organization (GO:0097435)3.34719498
27cellular response to ethanol (GO:0071361)3.34339630
28positive regulation of extracellular matrix organization (GO:1903055)3.33150612
29bone trabecula formation (GO:0060346)3.30608130
30regulation of telomerase activity (GO:0051972)3.30596025
31cartilage morphogenesis (GO:0060536)3.29773760
32phagocytosis, engulfment (GO:0006911)3.28584495
33virion attachment to host cell (GO:0019062)3.26950875
34adhesion of symbiont to host cell (GO:0044650)3.26950875
35cartilage condensation (GO:0001502)3.23869399
36cell aggregation (GO:0098743)3.23869399
37mRNA transcription from RNA polymerase II promoter (GO:0042789)3.22576246
38endothelial cell morphogenesis (GO:0001886)3.20955180
39chondroitin sulfate catabolic process (GO:0030207)3.16587422
40platelet dense granule organization (GO:0060155)3.16472200
41lymph vessel development (GO:0001945)3.15626507
42negative regulation of chondrocyte differentiation (GO:0032331)3.14553629
43vascular endothelial growth factor signaling pathway (GO:0038084)3.14458499
44mature B cell differentiation involved in immune response (GO:0002313)3.13970127
45antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G3.12839447
46chondrocyte development (GO:0002063)3.11605122
47extracellular fibril organization (GO:0043206)3.10756833
48cellular response to epinephrine stimulus (GO:0071872)3.10560660
49positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.09279652
50negative regulation of cAMP-mediated signaling (GO:0043951)3.04827251
51regulation of regulatory T cell differentiation (GO:0045589)3.01550004
52mRNA transcription (GO:0009299)2.98404886
53negative regulation of type 2 immune response (GO:0002829)2.97910475
54negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948)2.95950919
55collagen metabolic process (GO:0032963)2.94820284
56response to interleukin-15 (GO:0070672)2.94300885
57mitochondrial DNA replication (GO:0006264)2.93761784
58collagen catabolic process (GO:0030574)2.91339993
59negative T cell selection (GO:0043383)2.89893928
60keratan sulfate catabolic process (GO:0042340)2.89702462
61positive thymic T cell selection (GO:0045059)2.89620487
62cellular extravasation (GO:0045123)2.89170361
63negative thymic T cell selection (GO:0045060)2.88162924
64response to interferon-alpha (GO:0035455)2.87836059
65negative regulation of DNA biosynthetic process (GO:2000279)2.86810283
66L-fucose catabolic process (GO:0042355)2.86365670
67fucose catabolic process (GO:0019317)2.86365670
68L-fucose metabolic process (GO:0042354)2.86365670
69negative regulation of amyloid precursor protein catabolic process (GO:1902992)2.83857671
70response to epinephrine (GO:0071871)2.81867657
71galactose metabolic process (GO:0006012)2.78323392
72peptidyl-proline hydroxylation (GO:0019511)2.78310883
73negative regulation of biomineral tissue development (GO:0070168)2.76559038
74regulation of tight junction assembly (GO:2000810)2.74418741
75positive T cell selection (GO:0043368)2.73883390
76negative regulation of complement activation (GO:0045916)2.70145850
77nuclear envelope reassembly (GO:0031468)2.69387360
78mitotic nuclear envelope reassembly (GO:0007084)2.69387360
79multicellular organismal macromolecule metabolic process (GO:0044259)2.69145528
80lipopolysaccharide biosynthetic process (GO:0009103)2.68968576
81regulation of relaxation of muscle (GO:1901077)2.67498767
82secretory granule organization (GO:0033363)2.67476073
83regulation of integrin-mediated signaling pathway (GO:2001044)2.67430904
84negative regulation of fatty acid transport (GO:2000192)2.66976083
85antigen processing and presentation of endogenous peptide antigen (GO:0002483)2.66816778
86negative regulation of leukocyte chemotaxis (GO:0002689)2.65867352
87megakaryocyte development (GO:0035855)2.65153641
88negative regulation of stress fiber assembly (GO:0051497)2.64118229
89protein retention in ER lumen (GO:0006621)2.64110131
90negative regulation of T-helper cell differentiation (GO:0045623)2.62239801
91negative regulation of CD4-positive, alpha-beta T cell differentiation (GO:0043371)2.62239801
92cAMP catabolic process (GO:0006198)2.61436526
93cellular response to interleukin-15 (GO:0071350)2.61074400
94* glycosaminoglycan biosynthetic process (GO:0006024)2.60704983
95multicellular organismal catabolic process (GO:0044243)2.59964680
96negative regulation of synaptic transmission, GABAergic (GO:0032229)2.59544111
97wound healing, spreading of epidermal cells (GO:0035313)2.59534085
98mesodermal cell differentiation (GO:0048333)2.59373505
99cell migration involved in heart development (GO:0060973)2.59342038
100positive regulation of endothelial cell migration (GO:0010595)2.58474439
101antigen processing and presentation of endogenous antigen (GO:0019883)2.58432333
102endodermal cell differentiation (GO:0035987)2.58385881
103extracellular matrix disassembly (GO:0022617)2.58188172
104positive regulation of T cell differentiation in thymus (GO:0033089)2.57913701
105mature B cell differentiation (GO:0002335)2.57197981
106* aminoglycan biosynthetic process (GO:0006023)2.57018579
107adhesion of symbiont to host (GO:0044406)2.56557548
108positive regulation of gamma-delta T cell activation (GO:0046645)2.56514455
109regulation of gamma-delta T cell differentiation (GO:0045586)2.56018010
110* chondroitin sulfate metabolic process (GO:0030204)2.55902000
111cellular response to vitamin (GO:0071295)2.55538362
112cell adhesion mediated by integrin (GO:0033627)2.54378472
113activated T cell proliferation (GO:0050798)2.54029391
114regulation of extracellular matrix disassembly (GO:0010715)2.53855454
115activation of transmembrane receptor protein tyrosine kinase activity (GO:0007171)2.53808004
116tolerance induction (GO:0002507)2.52349377
117cyclic nucleotide catabolic process (GO:0009214)2.51541486
118maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.51033366
119sterol catabolic process (GO:0016127)2.50563122
120cholesterol catabolic process (GO:0006707)2.50563122
121negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.50463018
122regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547)2.50347939
123extracellular matrix assembly (GO:0085029)2.49845504
124negative regulation of actin filament bundle assembly (GO:0032232)2.49814105
125positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr2.49789132
126regulation of B cell receptor signaling pathway (GO:0050855)2.49624620
127multicellular organismal metabolic process (GO:0044236)2.49211193
128smooth muscle tissue development (GO:0048745)2.48192726
129negative regulation of cartilage development (GO:0061037)2.48059077
130endothelium development (GO:0003158)2.47754047
131peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800)2.46301638
132facial nerve structural organization (GO:0021612)2.45564958
133vascular endothelial growth factor receptor signaling pathway (GO:0048010)2.45012103
134positive regulation of granulocyte differentiation (GO:0030854)2.44757953
135positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.44129462
136negative regulation of lipopolysaccharide-mediated signaling pathway (GO:0031665)2.43781538
137positive regulation of endothelial cell apoptotic process (GO:2000353)2.43703321
138regulation of cardiac muscle cell contraction (GO:0086004)2.42947542
139cell communication by electrical coupling involved in cardiac conduction (GO:0086064)2.39367182
140negative regulation of protein autophosphorylation (GO:0031953)2.39196156
141negative regulation of protein activation cascade (GO:2000258)2.39174601
142regulation of gamma-delta T cell activation (GO:0046643)2.38530318
143positive regulation of Rap GTPase activity (GO:0032854)2.38065106
144regulation of beta-amyloid formation (GO:1902003)2.37629347
145negative regulation of alpha-beta T cell differentiation (GO:0046639)2.37391529
146antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)2.35101175
147regulation of ARF protein signal transduction (GO:0032012)2.32319295
148microglial cell activation (GO:0001774)2.32053900
149leukocyte aggregation (GO:0070486)2.31032148
150negative regulation of thymocyte apoptotic process (GO:0070244)2.30432650
151negative regulation of glycoprotein biosynthetic process (GO:0010561)2.30351461
152establishment of endothelial barrier (GO:0061028)2.29947292
153negative regulation of lymphocyte mediated immunity (GO:0002707)2.27907459
154thymic T cell selection (GO:0045061)2.27780477
155adaptation of signaling pathway (GO:0023058)2.26841734
156negative regulation of humoral immune response (GO:0002921)2.26303719
157inositol phosphate-mediated signaling (GO:0048016)2.24863924
158macrophage activation (GO:0042116)2.24415036
159regulation of memory T cell differentiation (GO:0043380)2.22953132
160regulation of germinal center formation (GO:0002634)2.18456774
161phosphatidylinositol dephosphorylation (GO:0046856)2.16917207
162regulation of gonadotropin secretion (GO:0032276)2.16258008
163phospholipid dephosphorylation (GO:0046839)2.15065938
164growth hormone receptor signaling pathway (GO:0060396)2.15046043
165production of molecular mediator involved in inflammatory response (GO:0002532)2.14127350
166positive regulation of tolerance induction (GO:0002645)2.13787492
167regulation of amyloid precursor protein catabolic process (GO:1902991)2.13346609
168T cell selection (GO:0045058)2.12242184
169regulation of T cell tolerance induction (GO:0002664)2.11812835
170germinal center formation (GO:0002467)2.10939972
171detection of molecule of bacterial origin (GO:0032490)2.09721027
172cellular response to growth hormone stimulus (GO:0071378)2.09232333
173regulation of actin filament-based movement (GO:1903115)2.08423578
174regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.07213223
175negative regulation of cytosolic calcium ion concentration (GO:0051481)2.07129288
176peptidyl-tyrosine autophosphorylation (GO:0038083)2.05637082
177thyroid hormone metabolic process (GO:0042403)2.05631865
178negative regulation of execution phase of apoptosis (GO:1900118)2.05191775
179negative regulation of B cell mediated immunity (GO:0002713)2.04038985
180negative regulation of immunoglobulin mediated immune response (GO:0002890)2.04038985
181regulation of T cell mediated cytotoxicity (GO:0001914)2.03263527
182thyroid hormone generation (GO:0006590)2.01789485
183positive regulation of gluconeogenesis (GO:0045722)2.01747717
184negative regulation of leukocyte mediated immunity (GO:0002704)2.00896969
185B cell receptor signaling pathway (GO:0050853)2.00373255
186protein targeting to Golgi (GO:0000042)2.00152101
187regulation of isotype switching to IgG isotypes (GO:0048302)1.99940052
188regulation of Rap GTPase activity (GO:0032317)1.99731440
189retrograde transport, vesicle recycling within Golgi (GO:0000301)1.99397198
190regulation of cell communication by electrical coupling (GO:0010649)1.98473751
191membrane depolarization during cardiac muscle cell action potential (GO:0086012)1.97935389
192RNA destabilization (GO:0050779)1.96130056
193myelin maintenance (GO:0043217)1.95585254
194long-term synaptic potentiation (GO:0060291)1.94852616
195astrocyte differentiation (GO:0048708)1.94367063
196relaxation of cardiac muscle (GO:0055119)1.93853635
197response to monoamine (GO:0071867)1.93050499

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1TRIM28_21343339_ChIP-Seq_HEK293_Human5.35057808
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.14629605
3PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse3.66302413
4FOXP3_17237761_ChIP-ChIP_TREG_Mouse3.52652059
5RARG_19884340_ChIP-ChIP_MEFs_Mouse3.30172965
6SMAD_19615063_ChIP-ChIP_OVARY_Human2.89897980
7IRF8_22096565_ChIP-ChIP_GC-B_Human2.83664335
8GBX2_23144817_ChIP-Seq_PC3_Human2.76174464
9SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.63118115
10BP1_19119308_ChIP-ChIP_Hs578T_Human2.57499410
11EED_16625203_ChIP-ChIP_MESCs_Mouse2.56479369
12SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.49136584
13SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.41589579
14* GATA2_21666600_ChIP-Seq_HMVEC_Human2.41420767
15* CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse2.40060453
16SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.36142017
17SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.34725174
18IKZF1_21737484_ChIP-ChIP_HCT116_Human2.32091093
19* CJUN_26792858_Chip-Seq_BT549_Human2.25553644
20RNF2_18974828_ChIP-Seq_MESCs_Mouse2.16469950
21EZH2_18974828_ChIP-Seq_MESCs_Mouse2.16469950
22AR_21572438_ChIP-Seq_LNCaP_Human2.16237969
23SCL_19346495_ChIP-Seq_HPC-7_Human2.13260869
24JARID2_20075857_ChIP-Seq_MESCs_Mouse2.06018305
25JARID2_20064375_ChIP-Seq_MESCs_Mouse1.98986012
26FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.93555927
27ESR1_21235772_ChIP-Seq_MCF-7_Human1.91139049
28ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.89066469
29BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.88859265
30* MTF2_20144788_ChIP-Seq_MESCs_Mouse1.88259665
31RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.83097960
32WT1_19549856_ChIP-ChIP_CCG9911_Human1.82664054
33PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.82065452
34NRF2_20460467_ChIP-Seq_MEFs_Mouse1.77403903
35NFE2L2_20460467_ChIP-Seq_MEFs_Mouse1.77403903
36GATA1_22025678_ChIP-Seq_K562_Human1.76533801
37HIF1A_21447827_ChIP-Seq_MCF-7_Human1.72550911
38EZH2_27304074_Chip-Seq_ESCs_Mouse1.71864314
39RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.66237271
40TP53_20018659_ChIP-ChIP_R1E_Mouse1.63457653
41EZH2_22144423_ChIP-Seq_EOC_Human1.60808234
42RNF2_27304074_Chip-Seq_ESCs_Mouse1.59361155
43FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.58363340
44STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.57985389
45ZNF274_21170338_ChIP-Seq_K562_Hela1.53946524
46* SUZ12_20075857_ChIP-Seq_MESCs_Mouse1.53180554
47RBPJ_22232070_ChIP-Seq_NCS_Mouse1.51744352
48SA1_22415368_ChIP-Seq_MEFs_Mouse1.51052959
49* CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.50345399
50NOTCH1_21737748_ChIP-Seq_TLL_Human1.48671845
51CDX2_19796622_ChIP-Seq_MESCs_Mouse1.48361711
52TP53_18474530_ChIP-ChIP_U2OS_Human1.47542497
53TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.47128723
54EP300_21415370_ChIP-Seq_HL-1_Mouse1.46350085
55EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse1.46154331
56* PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse1.40118942
57IRF8_27001747_Chip-Seq_BMDM_Mouse1.38176012
58LYL1_20887958_ChIP-Seq_HPC-7_Mouse1.37919255
59Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.37813594
60SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.36003708
61PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.34726576
62* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.33730018
63SALL4_18804426_ChIP-ChIP_XEN_Mouse1.33708586
64CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.33449284
65BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.32589915
66CLOCK_20551151_ChIP-Seq_293T_Human1.31488699
67EZH2_27294783_Chip-Seq_ESCs_Mouse1.30951242
68TP53_16413492_ChIP-PET_HCT116_Human1.28771748
69SUZ12_27294783_Chip-Seq_ESCs_Mouse1.27838728
70* SMC1_22415368_ChIP-Seq_MEFs_Mouse1.26769454
71IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.24745849
72BRD4_25478319_ChIP-Seq_HGPS_Human1.24414116
73TRIM28_17542650_ChIP-ChIP_NTERA2_Human1.24018533
74CHD7_19251738_ChIP-ChIP_MESCs_Mouse1.23066541
75ESR2_21235772_ChIP-Seq_MCF-7_Human1.23060180
76WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse1.20962814
77TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.20647941
78VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.20545734
79* ZFP57_27257070_Chip-Seq_ESCs_Mouse1.20495335
80SOX2_20726797_ChIP-Seq_SW620_Human1.17778188
81VDR_24787735_ChIP-Seq_THP-1_Human1.16721970
82RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.16283814
83RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.16166221
84NR3C1_23031785_ChIP-Seq_PC12_Mouse1.15006881
85AHR_22903824_ChIP-Seq_MCF-7_Human1.14434483
86* SMC3_22415368_ChIP-Seq_MEFs_Mouse1.13870885
87* FOXO3_23340844_ChIP-Seq_DLD1_Human1.13546765
88RXR_22108803_ChIP-Seq_LS180_Human1.13350814
89PIAS1_25552417_ChIP-Seq_VCAP_Human1.10619246
90ARNT_22903824_ChIP-Seq_MCF-7_Human1.09824383
91NR1I2_20693526_ChIP-Seq_LIVER_Mouse1.08824887
92SPI1_23127762_ChIP-Seq_K562_Human1.08813336
93ELK3_25401928_ChIP-Seq_HUVEC_Human1.08530006
94SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.07416186
95HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.05136055
96GATA3_27048872_Chip-Seq_THYMUS_Human1.04827651
97ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human1.04649203
98STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.04622751
99THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.03607589
100PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.02754953
101TCF4_18268006_ChIP-ChIP_LS174T_Human1.02739072
102MYB_26560356_Chip-Seq_TH2_Human1.02586920
103* P300_19829295_ChIP-Seq_ESCs_Human1.01963428
104DROSHA_22980978_ChIP-Seq_HELA_Human1.01780327
105NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.01387339
106FLI1_27457419_Chip-Seq_LIVER_Mouse0.99100660
107MYB_21317192_ChIP-Seq_ERMYB_Mouse0.98710040
108EOMES_21245162_ChIP-Seq_HESCs_Human0.97688207
109* GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95987384
110CTBP2_25329375_ChIP-Seq_LNCAP_Human0.95386423
111* WT1_25993318_ChIP-Seq_PODOCYTE_Human0.95286934
112RING1B_27294783_Chip-Seq_ESCs_Mouse0.95133683
113STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.93982605
114TBX20_22328084_ChIP-Seq_HEART_Mouse0.93879133
115TBX20_22080862_ChIP-Seq_HEART_Mouse0.93879133
116SMAD3_21741376_ChIP-Seq_HESCs_Human0.93261747
117ZNF217_24962896_ChIP-Seq_MCF-7_Human0.92370862
118GATA3_26560356_Chip-Seq_TH2_Human0.91346959
119FOXO1_23066095_ChIP-Seq_LIVER_Mouse0.90945470
120CTNNB1_20460455_ChIP-Seq_HCT116_Human0.90341315
121E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.89912115
122STAT6_21828071_ChIP-Seq_BEAS2B_Human0.89828328
123FUS_26573619_Chip-Seq_HEK293_Human0.88937595
124PCGF2_27294783_Chip-Seq_NPCs_Mouse0.87415694
125TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.87319297
126* SMAD4_21799915_ChIP-Seq_A2780_Human0.87291176
127* TP53_23651856_ChIP-Seq_MEFs_Mouse0.86980110
128SUZ12_27294783_Chip-Seq_NPCs_Mouse0.86977387
129* FOXA2_19822575_ChIP-Seq_HepG2_Human0.86921034
130PCGF2_27294783_Chip-Seq_ESCs_Mouse0.86869489
131RUNX1_17652178_ChIP-ChIP_JURKAT_Human0.86762315
132* STAT3_23295773_ChIP-Seq_U87_Human0.86711751
133BCAT_22108803_ChIP-Seq_LS180_Human0.86555085
134EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human0.86191374
135PRDM14_20953172_ChIP-Seq_ESCs_Human0.85747674
136TP63_23658742_ChIP-Seq_EP156T_Human0.85687363
137FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.84980415
138SMAD2_18955504_ChIP-ChIP_HaCaT_Human0.84789772
139SMAD3_18955504_ChIP-ChIP_HaCaT_Human0.84789772
140* SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.84760177
141EZH2_27294783_Chip-Seq_NPCs_Mouse0.83831204
142MECOM_23826213_ChIP-Seq_KASUMI_Mouse0.83619930
143CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.83595914
144* RUNX_20019798_ChIP-Seq_JUKART_Human0.82952772
145* OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse0.82910395
146AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.82417791
147SMRT_27268052_Chip-Seq_Bcells_Human0.82274357
148LXR_22158963_ChIP-Seq_LIVER_Mouse0.81881085
149GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.81815954
150AR_25329375_ChIP-Seq_VCAP_Human0.81215614
151RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse0.80222541
152NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.80172863
153TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.79821619
154SCL_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.79723480
155CTBP1_25329375_ChIP-Seq_LNCAP_Human0.78923746
156CBX2_27304074_Chip-Seq_ESCs_Mouse0.78629320
157JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.78532090
158IRF8_21731497_ChIP-ChIP_J774_Mouse0.78018231
159* TCF4_23295773_ChIP-Seq_U87_Human0.77580026
160ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.77391330

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0008438_abnormal_cutaneous_collagen6.58429160
2MP0005503_abnormal_tendon_morphology5.10170984
3MP0003279_aneurysm4.98762872
4MP0001958_emphysema4.36322558
5MP0003705_abnormal_hypodermis_morpholog4.09391421
6MP0005275_abnormal_skin_tensile4.00591464
7MP0009384_cardiac_valve_regurgitation3.97944006
8MP0006054_spinal_hemorrhage2.98808130
9MP0010368_abnormal_lymphatic_system2.60276598
10MP0002166_altered_tumor_susceptibility2.58029880
11MP0002876_abnormal_thyroid_physiology2.51386351
12MP0001986_abnormal_taste_sensitivity2.39847480
13MP0005623_abnormal_meninges_morphology2.32236612
14MP0001879_abnormal_lymphatic_vessel2.29523322
15MP0003436_decreased_susceptibility_to2.26693751
16MP0004272_abnormal_basement_membrane2.22333683
17MP0001501_abnormal_sleep_pattern2.16393579
18MP0002282_abnormal_trachea_morphology2.01340846
19MP0000685_abnormal_immune_system1.97959536
20MP0003763_abnormal_thymus_physiology1.97168169
21MP0002009_preneoplasia1.97064815
22MP0005508_abnormal_skeleton_morphology1.96355250
23MP0002933_joint_inflammation1.96035753
24MP0004134_abnormal_chest_morphology1.93909130
25MP0003941_abnormal_skin_development1.93815503
26MP0003303_peritoneal_inflammation1.86493652
27MP0009250_abnormal_appendicular_skeleto1.84936698
28MP0005171_absent_coat_pigmentation1.80617533
29MP0004808_abnormal_hematopoietic_stem1.72360489
30MP0001835_abnormal_antigen_presentation1.71040238
31MP0002295_abnormal_pulmonary_circulatio1.67609115
32MP0003724_increased_susceptibility_to1.65901870
33MP0002006_tumorigenesis1.65645841
34MP0002060_abnormal_skin_morphology1.59794118
35MP0001800_abnormal_humoral_immune1.55075845
36MP0005671_abnormal_response_to1.53377596
37MP0005000_abnormal_immune_tolerance1.52810275
38MP0001542_abnormal_bone_strength1.51436198
39MP0009785_altered_susceptibility_to1.50616438
40MP0009379_abnormal_foot_pigmentation1.49973274
41MP0002419_abnormal_innate_immunity1.48554569
42MP0000767_abnormal_smooth_muscle1.48519313
43MP0001299_abnormal_eye_distance/1.44499628
44MP0003172_abnormal_lysosome_physiology1.41095954
45MP0004147_increased_porphyrin_level1.40535017
46MP0005387_immune_system_phenotype1.38875838
47MP0001790_abnormal_immune_system1.38875838
48MP0002089_abnormal_postnatal_growth/wei1.38123325
49MP0003300_gastrointestinal_ulcer1.37900356
50MP0003690_abnormal_glial_cell1.36324422
51MP0005595_abnormal_vascular_smooth1.35764178
52MP0000569_abnormal_digit_pigmentation1.35428569
53MP0002249_abnormal_larynx_morphology1.35046937
54MP0004130_abnormal_muscle_cell1.34852126
55MP0005390_skeleton_phenotype1.34638657
56* MP0000163_abnormal_cartilage_morphology1.33432798
57MP0001188_hyperpigmentation1.33414348
58MP0009278_abnormal_bone_marrow1.32628147
59MP0008004_abnormal_stomach_pH1.31034181
60MP0002723_abnormal_immune_serum1.30487502
61MP0002108_abnormal_muscle_morphology1.30446021
62MP0002896_abnormal_bone_mineralization1.28563338
63MP0005023_abnormal_wound_healing1.27738271
64MP0003091_abnormal_cell_migration1.23939910
65MP0000762_abnormal_tongue_morphology1.23816048
66MP0003566_abnormal_cell_adhesion1.22372358
67MP0000465_gastrointestinal_hemorrhage1.22239560
68MP0005084_abnormal_gallbladder_morpholo1.21337569
69MP0009745_abnormal_behavioral_response1.21262026
70MP0003633_abnormal_nervous_system1.20789366
71* MP0002115_abnormal_skeleton_extremities1.20073909
72MP0002420_abnormal_adaptive_immunity1.19591982
73MP0001819_abnormal_immune_cell1.17028038
74MP0010155_abnormal_intestine_physiology1.16485858
75MP0005025_abnormal_response_to1.15845700
76MP0004947_skin_inflammation1.13630307
77MP0003283_abnormal_digestive_organ1.13123152
78MP0000343_altered_response_to1.12913403
79MP0002909_abnormal_adrenal_gland1.12506631
80MP0002452_abnormal_antigen_presenting1.12004148
81MP0004859_abnormal_synaptic_plasticity1.10196627
82MP0005165_increased_susceptibility_to1.08845062
83MP0003385_abnormal_body_wall1.08659999
84MP0002837_dystrophic_cardiac_calcinosis1.08238106
85* MP0002113_abnormal_skeleton_development1.06733998
86MP0001533_abnormal_skeleton_physiology1.06665994
87MP0009780_abnormal_chondrocyte_physiolo1.06654427
88MP0002932_abnormal_joint_morphology1.05696659
89MP0002064_seizures1.04166244
90MP0002128_abnormal_blood_circulation1.03935299
91MP0004381_abnormal_hair_follicle1.03415557
92MP0002148_abnormal_hypersensitivity_rea1.02676753
93MP0006138_congestive_heart_failure1.00644102
94MP0001270_distended_abdomen0.99762457
95MP0002168_other_aberrant_phenotype0.99188943
96MP0003195_calcinosis0.98155162
97MP0002693_abnormal_pancreas_physiology0.96950938
98MP0005310_abnormal_salivary_gland0.96546777
99MP0002405_respiratory_system_inflammati0.96038193
100MP0002998_abnormal_bone_remodeling0.95302492
101MP0000920_abnormal_myelination0.94703507
102MP0004883_abnormal_blood_vessel0.94295583
103MP0000013_abnormal_adipose_tissue0.92406645
104MP0005166_decreased_susceptibility_to0.92283692
105MP0001486_abnormal_startle_reflex0.91861649
106MP0000751_myopathy0.91410877
107MP0005164_abnormal_response_to0.91019157
108MP0001756_abnormal_urination0.90628120
109MP0001243_abnormal_dermal_layer0.89959236
110MP0002138_abnormal_hepatobiliary_system0.88859723
111MP0002133_abnormal_respiratory_system0.87594197
112MP0005388_respiratory_system_phenotype0.87594197
113MP0003329_amyloid_beta_deposits0.86653021
114MP0001502_abnormal_circadian_rhythm0.85037770
115MP0005257_abnormal_intraocular_pressure0.84631329
116MP0002736_abnormal_nociception_after0.84537172
117MP0000003_abnormal_adipose_tissue0.84378909
118MP0001765_abnormal_ion_homeostasis0.84359226
119MP0000049_abnormal_middle_ear0.83996060
120MP0004510_myositis0.83799486
121MP0003631_nervous_system_phenotype0.83657807
122MP0003880_abnormal_central_pattern0.83361484
123MP0010030_abnormal_orbit_morphology0.83257912
124MP0003866_abnormal_defecation0.82407027
125MP0001853_heart_inflammation0.81673967
126MP0004885_abnormal_endolymph0.81264080
127MP0000716_abnormal_immune_system0.79835173
128MP0004270_analgesia0.79289057
129MP0003075_altered_response_to0.78594677
130MP0003191_abnormal_cellular_cholesterol0.77855480
131MP0001845_abnormal_inflammatory_respons0.77446145
132MP0002638_abnormal_pupillary_reflex0.77042189
133MP0004215_abnormal_myocardial_fiber0.77017055
134MP0002254_reproductive_system_inflammat0.76526436
135MP0002398_abnormal_bone_marrow0.76430870
136MP0008775_abnormal_heart_ventricle0.75767748
137MP0003795_abnormal_bone_structure0.75629851
138MP0000230_abnormal_systemic_arterial0.75357065
139MP0003828_pulmonary_edema0.75310623
140MP0003635_abnormal_synaptic_transmissio0.74705134
141MP0002272_abnormal_nervous_system0.73604554
142MP0001545_abnormal_hematopoietic_system0.72303223
143MP0005397_hematopoietic_system_phenotyp0.72303223
144MP0003943_abnormal_hepatobiliary_system0.72066069
145MP0000681_abnormal_thyroid_gland0.69799277
146MP0001614_abnormal_blood_vessel0.69483286
147* MP0002109_abnormal_limb_morphology0.69091648
148MP0000749_muscle_degeneration0.68579051
149MP0004858_abnormal_nervous_system0.66974825
150MP0005167_abnormal_blood-brain_barrier0.66681838
151* MP0002114_abnormal_axial_skeleton0.65501271
152MP0000249_abnormal_blood_vessel0.64936100
153MP0004484_altered_response_of0.63980384
154MP0001851_eye_inflammation0.63722406
155MP0005464_abnormal_platelet_physiology0.62723789
156MP0003942_abnormal_urinary_system0.62574565
157MP0004084_abnormal_cardiac_muscle0.58889286
158MP0010771_integument_phenotype0.56168137
159MP0002116_abnormal_craniofacial_bone0.56089698
160MP0000432_abnormal_head_morphology0.52695994
161MP0004036_abnormal_muscle_relaxation0.52635561
162MP0000516_abnormal_urinary_system0.51361189
163MP0005367_renal/urinary_system_phenotyp0.51361189
164MP0008874_decreased_physiological_sensi0.49216551
165MP0002396_abnormal_hematopoietic_system0.48639045
166MP0001175_abnormal_lung_morphology0.47439768
167MP0003045_fibrosis0.46520608
168MP0001177_atelectasis0.46339378

Predicted human phenotypes

RankGene SetZ-score
1Protrusio acetabuli (HP:0003179)6.87223257
2Beaking of vertebral bodies (HP:0004568)5.77921415
3Premature rupture of membranes (HP:0001788)5.39154690
4Patchy hypopigmentation of hair (HP:0011365)5.00155754
5Neonatal short-limb short stature (HP:0008921)4.79898864
6Panhypogammaglobulinemia (HP:0003139)4.64148477
7T lymphocytopenia (HP:0005403)4.40875762
8Thyroiditis (HP:0100646)4.37282241
9Severe combined immunodeficiency (HP:0004430)4.26380164
10Hypoplasia of the thymus (HP:0000778)4.21204604
11Spinal rigidity (HP:0003306)4.20418887
12B lymphocytopenia (HP:0010976)4.18046482
13Abnormality of B cell number (HP:0010975)4.10232064
14Aortic aneurysm (HP:0004942)4.09238471
15Aortic dissection (HP:0002647)4.02945493
16Abnormality of T cell number (HP:0011839)4.01951729
17Biconcave vertebral bodies (HP:0004586)3.68842113
18Soft skin (HP:0000977)3.68483863
19Hypoproteinemia (HP:0003075)3.68466116
20Eosinophilia (HP:0001880)3.63800286
21Stomatitis (HP:0010280)3.62220922
22Vertebral compression fractures (HP:0002953)3.59451195
23Eczematoid dermatitis (HP:0000976)3.57703982
24Vascular tortuosity (HP:0004948)3.48143028
25Generalized amyotrophy (HP:0003700)3.41844467
26Overlapping toe (HP:0001845)3.40761535
27Epiphyseal dysplasia (HP:0002656)3.40081866
28Large for gestational age (HP:0001520)3.37265386
29Recurrent fungal infections (HP:0002841)3.34982851
30Arterial tortuosity (HP:0005116)3.30108294
31Abnormality of dentin (HP:0010299)3.29289319
32Peritonitis (HP:0002586)3.28310955
33Atrophic scars (HP:0001075)3.20103412
34Follicular hyperkeratosis (HP:0007502)3.11131734
35Granulocytopenia (HP:0001913)3.10448972
36Rib fusion (HP:0000902)3.10230467
37Cervical subluxation (HP:0003308)3.06025599
38Overgrowth (HP:0001548)3.04454119
39Myositis (HP:0100614)3.03045228
40Broad metatarsal (HP:0001783)3.02639439
41Dilatation of the ascending aorta (HP:0005111)3.00848966
42Abnormality of eosinophils (HP:0001879)3.00171456
43Bladder diverticulum (HP:0000015)2.99685941
44Increased CSF protein (HP:0002922)2.92627043
45Spontaneous hematomas (HP:0007420)2.91161158
46Elevated erythrocyte sedimentation rate (HP:0003565)2.89951818
47Wormian bones (HP:0002645)2.89468455
48Hemiplegia (HP:0002301)2.89013719
49Joint stiffness (HP:0001387)2.88023926
50Fragile skin (HP:0001030)2.87222355
51Abnormality of macular pigmentation (HP:0008002)2.85904781
52Papilledema (HP:0001085)2.85678205
53Cupped ribs (HP:0000887)2.84743579
54Abnormality of skull ossification (HP:0002703)2.84654193
55Decreased skull ossification (HP:0004331)2.84151460
56Abnormality of the lumbar spine (HP:0100712)2.82330139
57Hematochezia (HP:0002573)2.80104439
58Abnormality of T cells (HP:0002843)2.79642377
59Combined immunodeficiency (HP:0005387)2.77017481
60Radial bowing (HP:0002986)2.73540277
61Orchitis (HP:0100796)2.69911892
62Ankle contracture (HP:0006466)2.69348872
63Episodic fever (HP:0001954)2.65150949
64Agammaglobulinemia (HP:0004432)2.63959314
65Retrobulbar optic neuritis (HP:0100654)2.62015374
66Optic neuritis (HP:0100653)2.62015374
67Coxa vara (HP:0002812)2.60441159
68Leukocytosis (HP:0001974)2.56695331
69Ectopia lentis (HP:0001083)2.56149153
70Supernumerary nipples (HP:0002558)2.56031202
71Flat face (HP:0012368)2.55664882
72Meningitis (HP:0001287)2.53198112
73Stomach cancer (HP:0012126)2.44969675
74Absent frontal sinuses (HP:0002688)2.44422020
75Coarse hair (HP:0002208)2.44253087
76Bowel diverticulosis (HP:0005222)2.42888334
77Verrucae (HP:0200043)2.42853016
78Papilloma (HP:0012740)2.42853016
79Wide nose (HP:0000445)2.42048631
80Flat capital femoral epiphysis (HP:0003370)2.38160845
81Abnormal delayed hypersensitivity skin test (HP:0002963)2.37108440
82Shawl scrotum (HP:0000049)2.36709967
83Irregular epiphyses (HP:0010582)2.36093275
84Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.35774213
85Osteoarthritis (HP:0002758)2.35184719
86Infantile muscular hypotonia (HP:0008947)2.33587980
87Mild short stature (HP:0003502)2.32316200
88Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)2.32105988
89Blue sclerae (HP:0000592)2.31428812
90Shallow orbits (HP:0000586)2.30516040
91Ovoid vertebral bodies (HP:0003300)2.28347726
92IgG deficiency (HP:0004315)2.27620053
93Bundle branch block (HP:0011710)2.26059921
94Hemiparesis (HP:0001269)2.25389438
95Congenital sensorineural hearing impairment (HP:0008527)2.25300414
96Craniofacial hyperostosis (HP:0004493)2.24496880
97Recurrent viral infections (HP:0004429)2.23730365
98Action tremor (HP:0002345)2.22580235
99Testicular neoplasm (HP:0010788)2.21920484
100Abnormality of the acetabulum (HP:0003170)2.21279343
101Ventricular fibrillation (HP:0001663)2.19362379
102Aortic valve stenosis (HP:0001650)2.19029259
103Growth hormone excess (HP:0000845)2.18442341
104Increased IgE level (HP:0003212)2.18406222
105Syncope (HP:0001279)2.18038997
106Abnormality of binocular vision (HP:0011514)2.16683396
107Diplopia (HP:0000651)2.16683396
108Febrile seizures (HP:0002373)2.16385839
109Abnormal delivery (HP:0001787)2.15273461
110Striae distensae (HP:0001065)2.13728951
111Recurrent bronchitis (HP:0002837)2.13543154
112Sepsis (HP:0100806)2.13276675
113Atrial fibrillation (HP:0005110)2.13039503
114Abnormality of primary teeth (HP:0006481)2.10467433
115Pulmonary infiltrates (HP:0002113)2.09530199
116Genu recurvatum (HP:0002816)2.08336882
117Asymmetry of the thorax (HP:0001555)2.06922850
118Nasal speech (HP:0001611)2.06759480
119Enlarged penis (HP:0000040)2.06323343
120Self-mutilation (HP:0000742)2.03549666
121Osteomyelitis (HP:0002754)2.02641880
122Small epiphyses (HP:0010585)2.01701875
123Sprengel anomaly (HP:0000912)1.99843371
124Abnormal tarsal ossification (HP:0008369)1.98575227
125Abnormality of the phalanges of the 2nd finger (HP:0009541)1.97393343
126Gastrointestinal infarctions (HP:0005244)1.97377570
127Abnormality of the frontal sinuses (HP:0002687)1.97301774
128Vitreoretinal degeneration (HP:0000655)1.96982704
129Parkinsonism with favorable response to dopaminergic medication (HP:0002548)1.94511762
130Pustule (HP:0200039)1.94016779
131Cellulitis (HP:0100658)1.93836366
132Thin bony cortex (HP:0002753)1.93751052
133Hyperextensible skin (HP:0000974)1.93714520
134Short nail (HP:0001799)1.93304042
135Hyporeflexia of lower limbs (HP:0002600)1.93163041
136Spinal cord lesions (HP:0100561)1.93118767
137Syringomyelia (HP:0003396)1.93118767
138Spinal cord compression (HP:0002176)1.92545075
139Aplasia involving bones of the extremities (HP:0009825)1.92530051
140Aplasia involving bones of the upper limbs (HP:0009823)1.92530051
141Aplasia of the phalanges of the hand (HP:0009802)1.92530051
142Fatigue (HP:0012378)1.92424950
143Keratoconjunctivitis (HP:0001096)1.91361451
144Mitral regurgitation (HP:0001653)1.91000756
145Generalized hypopigmentation of hair (HP:0011358)1.90988461
146Spondylolisthesis (HP:0003302)1.90958925
147Delayed closure of the anterior fontanelle (HP:0001476)1.89972307
148Abnormality of the axillary hair (HP:0100134)1.89626765
149Abnormality of secondary sexual hair (HP:0009888)1.89626765
150Recurrent abscess formation (HP:0002722)1.89557869
151Inguinal hernia (HP:0000023)1.89376393
152Prolonged bleeding time (HP:0003010)1.88910341
153Primary atrial arrhythmia (HP:0001692)1.88341825
154Aplasia/Hypoplasia involving the sinuses (HP:0009120)1.87701903
155Recurrent gram-negative bacterial infections (HP:0005420)1.87302343
156Gaze-evoked nystagmus (HP:0000640)1.87115558
157Mesomelia (HP:0003027)1.86607009
158Cranial hyperostosis (HP:0004437)1.85923223
159Subacute progressive viral hepatitis (HP:0006572)1.85613542
160Hypoplastic ischia (HP:0003175)1.85353749
161Sparse eyelashes (HP:0000653)1.85024466
162Widely spaced teeth (HP:0000687)1.84664618
163Amyloidosis (HP:0011034)1.84196582
164Abnormal number of erythroid precursors (HP:0012131)1.84135299
165Hypothermia (HP:0002045)1.83139175
166Mitral valve prolapse (HP:0001634)1.81207841
167Bowing of the arm (HP:0006488)1.81187425
168Bowed forearm bones (HP:0003956)1.81187425
169Lumbar hyperlordosis (HP:0002938)1.80163986
170Blue irides (HP:0000635)1.79997522
171Hyperlipoproteinemia (HP:0010980)1.79190661
172Mitral stenosis (HP:0001718)1.79097125
173Keratoconjunctivitis sicca (HP:0001097)1.77615811
174Abnormality of T cell physiology (HP:0011840)1.77389128
175Abnormality of the 2nd finger (HP:0004100)1.77027513
176Spinal canal stenosis (HP:0003416)1.76501680
177Hemoptysis (HP:0002105)1.76489763
178Joint swelling (HP:0001386)1.75317207
179Progressive cerebellar ataxia (HP:0002073)1.75298019
180Bradycardia (HP:0001662)1.74679842
181Global brain atrophy (HP:0002283)1.74093578
182Abnormality of macrophages (HP:0004311)1.74032413
183Supraventricular arrhythmia (HP:0005115)1.73623843
184Abnormal EKG (HP:0003115)1.73563169
185Ventricular arrhythmia (HP:0004308)1.72837306
186Cerebral aneurysm (HP:0004944)1.72753539
187Mediastinal lymphadenopathy (HP:0100721)1.72638221
188Gingival bleeding (HP:0000225)1.72359100
189Supraventricular tachycardia (HP:0004755)1.72207010
190Obstructive sleep apnea (HP:0002870)1.71595063
191Abnormality of mucopolysaccharide metabolism (HP:0011020)1.71437398
192Abnormality of polysaccharide metabolism (HP:0011012)1.71437398
193Abnormality of glycosaminoglycan metabolism (HP:0004371)1.71437398
194Prolonged QT interval (HP:0001657)1.71186470
195Heart block (HP:0012722)1.70351812
196Hypokalemic alkalosis (HP:0001949)1.69856296
197Fair hair (HP:0002286)1.68977708

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TRIB33.76512365
2MAP2K33.72759472
3MUSK3.72227054
4TIE13.58372245
5EEF2K3.44142987
6PKN23.37942738
7TNIK3.33098844
8INSRR3.06074041
9DDR22.83654396
10MAP3K32.83579701
11FRK2.55324492
12MAPKAPK52.53675093
13TAOK32.31551786
14MAP2K62.24341199
15FGFR32.21169172
16MAPKAPK32.06044711
17VRK11.98397312
18MAP4K11.93538589
19RIPK41.85886164
20TGFBR21.85494809
21NLK1.83348764
22TRPM71.79489044
23NTRK31.78377491
24STK381.74440806
25ZAP701.66840320
26PIM21.65793700
27MYLK1.65391581
28JAK11.64383531
29TGFBR11.62573158
30RPS6KA41.59987934
31LATS21.59709628
32MAP3K131.57156205
33KDR1.56716092
34TXK1.55641273
35EPHB11.53757064
36PRPF4B1.42712596
37PRKG21.42693398
38ITK1.38302416
39CASK1.34651100
40MKNK11.31831535
41EPHA31.31137734
42PAK31.28646203
43TYK21.26440046
44MAPK121.25530191
45GRK61.22659080
46SIK11.21135806
47LRRK21.21015110
48MAPK131.15898112
49MAP3K71.13907716
50ERBB31.11904505
51MAP3K121.11579155
52CSK1.10817785
53FES1.07986113
54CAMKK21.07339979
55EIF2AK31.03068170
56MAP3K141.02381335
57STK241.00932790
58ILK1.00838703
59MKNK20.98987562
60CAMKK10.98533767
61RPS6KB20.96800859
62ERN10.96790061
63KIT0.96134067
64DAPK20.95813822
65SYK0.93746301
66NEK60.93621300
67MARK20.93297261
68PRKD30.93125448
69IRAK10.92821509
70BMPR1B0.92600118
71IKBKE0.91380429
72FGFR20.91141402
73STK110.89236710
74MAP2K20.89057544
75HCK0.88219999
76PTK2B0.87516639
77MAP3K10.86973924
78PTK60.86708689
79SIK30.85174107
80BLK0.84336727
81BMPR20.82911735
82GRK50.82595640
83CAMK40.82337950
84LCK0.78915915
85CAMK10.78586304
86FGFR10.78310179
87RAF10.75786634
88CDC42BPA0.74512529
89PAK20.73749462
90PINK10.73734882
91UHMK10.72525153
92YES10.71869916
93SGK20.71842734
94IRAK40.71764512
95PDGFRA0.71419717
96MAP2K70.70655528
97JAK20.70179440
98BTK0.69762395
99NTRK20.69505779
100PIK3CA0.69408434
101NME10.67841624
102MAP3K20.66984115
103CDK190.65809514
104STK160.65649952
105FGFR40.65365386
106STK40.64579973
107PRKAA20.64329316
108LYN0.64296552
109WNK10.64261415
110SGK4940.63345158
111SGK2230.63345158
112HIPK20.63281942
113MAPK70.62491822
114MOS0.61640075
115STK390.61273247
116NME20.60947483
117NTRK10.60221454
118FER0.59113261
119PDK10.58794944
120MAPK110.57366133
121LMTK20.56801823
122RET0.56599998
123DMPK0.56415459
124PRKD20.55386723
125TBK10.54136824
126TTN0.53726472
127EIF2AK10.50632826
128RIPK10.50407458
129MATK0.49284504
130MET0.48732096
131PHKG10.48309238
132PHKG20.48309238
133MAPK40.48225164
134MAP2K10.47283004
135ADRBK10.46990570
136IKBKB0.46873376
137GRK10.46760231
138TEC0.45811654
139PAK40.45315187
140PRKCH0.45252619
141PIK3CG0.43139377
142CSF1R0.41501015
143ROCK10.40820425
144JAK30.38616717
145PRKD10.38043273
146PRKCE0.37899170
147NUAK10.37784998
148MAP3K60.37109406
149EPHA40.35864809
150MINK10.35831992
151IGF1R0.34772255
152PDPK10.32235121
153PDGFRB0.28192982
154MAPKAPK20.27811817
155TNK20.27162275
156EIF2AK20.26628584
157SGK30.26380764
158SRC0.26363643
159RPS6KB10.26360528

Predicted pathways (KEGG)

RankGene SetZ-score
1* Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005324.27705320
2ECM-receptor interaction_Homo sapiens_hsa045123.49176950
3Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005332.88755542
4Malaria_Homo sapiens_hsa051442.74452653
5Platelet activation_Homo sapiens_hsa046112.44519023
6Focal adhesion_Homo sapiens_hsa045102.07795615
7AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049332.05233892
8Protein digestion and absorption_Homo sapiens_hsa049741.92244604
9Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005121.88805494
10Primary immunodeficiency_Homo sapiens_hsa053401.88528908
11Dorso-ventral axis formation_Homo sapiens_hsa043201.66788045
12Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.59180161
13Circadian rhythm_Homo sapiens_hsa047101.56332551
14Shigellosis_Homo sapiens_hsa051311.51285325
15GnRH signaling pathway_Homo sapiens_hsa049121.46132832
16Salivary secretion_Homo sapiens_hsa049701.43606771
17Phosphatidylinositol signaling system_Homo sapiens_hsa040701.43506446
18Other types of O-glycan biosynthesis_Homo sapiens_hsa005141.40913710
19T cell receptor signaling pathway_Homo sapiens_hsa046601.38129974
20PI3K-Akt signaling pathway_Homo sapiens_hsa041511.32752857
21Rap1 signaling pathway_Homo sapiens_hsa040151.31806321
22Circadian entrainment_Homo sapiens_hsa047131.30465222
23Autoimmune thyroid disease_Homo sapiens_hsa053201.29765958
24Morphine addiction_Homo sapiens_hsa050321.29698195
25Neurotrophin signaling pathway_Homo sapiens_hsa047221.28041030
26Dilated cardiomyopathy_Homo sapiens_hsa054141.27587689
27Proteoglycans in cancer_Homo sapiens_hsa052051.26568365
28B cell receptor signaling pathway_Homo sapiens_hsa046621.26346023
29Gastric acid secretion_Homo sapiens_hsa049711.22955379
30African trypanosomiasis_Homo sapiens_hsa051431.22663900
31Inositol phosphate metabolism_Homo sapiens_hsa005621.18139077
32Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.17941805
33Glutamatergic synapse_Homo sapiens_hsa047241.17346175
34Gap junction_Homo sapiens_hsa045401.16172269
35Amphetamine addiction_Homo sapiens_hsa050311.15385522
36Aldosterone synthesis and secretion_Homo sapiens_hsa049251.14976259
37Glycosaminoglycan degradation_Homo sapiens_hsa005311.13710618
38Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.13514672
39Nitrogen metabolism_Homo sapiens_hsa009101.12061468
40Regulation of lipolysis in adipocytes_Homo sapiens_hsa049231.11233695
41Renin secretion_Homo sapiens_hsa049241.10748130
42Retrograde endocannabinoid signaling_Homo sapiens_hsa047231.09651386
43Long-term depression_Homo sapiens_hsa047301.09260434
44Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.08804161
45FoxO signaling pathway_Homo sapiens_hsa040681.08094023
46Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.07651077
47Sphingolipid metabolism_Homo sapiens_hsa006001.07438373
48N-Glycan biosynthesis_Homo sapiens_hsa005101.07175752
49Jak-STAT signaling pathway_Homo sapiens_hsa046301.06003410
50Long-term potentiation_Homo sapiens_hsa047201.04734343
51Melanogenesis_Homo sapiens_hsa049161.03131005
52TNF signaling pathway_Homo sapiens_hsa046681.02803097
53Type I diabetes mellitus_Homo sapiens_hsa049401.02433415
54Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054101.01463721
55Calcium signaling pathway_Homo sapiens_hsa040201.01036457
56Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.99866920
57SNARE interactions in vesicular transport_Homo sapiens_hsa041300.99459322
58Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.98498998
59Vascular smooth muscle contraction_Homo sapiens_hsa042700.95936292
60NOD-like receptor signaling pathway_Homo sapiens_hsa046210.94694132
61Oxytocin signaling pathway_Homo sapiens_hsa049210.94369059
62Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.94139189
63Cholinergic synapse_Homo sapiens_hsa047250.92384078
64VEGF signaling pathway_Homo sapiens_hsa043700.92127587
65Other glycan degradation_Homo sapiens_hsa005110.91377880
66Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.90627470
67Renal cell carcinoma_Homo sapiens_hsa052110.88014315
68Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.87885837
69RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.86713645
70Tuberculosis_Homo sapiens_hsa051520.86671151
71Chemokine signaling pathway_Homo sapiens_hsa040620.85934237
72mTOR signaling pathway_Homo sapiens_hsa041500.85429799
73Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046660.85182518
74ABC transporters_Homo sapiens_hsa020100.83307879
75Graft-versus-host disease_Homo sapiens_hsa053320.83081063
76Leishmaniasis_Homo sapiens_hsa051400.81499471
77Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.81389194
78Serotonergic synapse_Homo sapiens_hsa047260.81381720
79Allograft rejection_Homo sapiens_hsa053300.80652181
80Pertussis_Homo sapiens_hsa051330.80244527
81Amoebiasis_Homo sapiens_hsa051460.79844980
82Prolactin signaling pathway_Homo sapiens_hsa049170.79431677
83Fc epsilon RI signaling pathway_Homo sapiens_hsa046640.79280070
84Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.79189312
85Sphingolipid signaling pathway_Homo sapiens_hsa040710.79187182
86Ovarian steroidogenesis_Homo sapiens_hsa049130.79059729
87Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.79056984
88cGMP-PKG signaling pathway_Homo sapiens_hsa040220.79001202
89Taste transduction_Homo sapiens_hsa047420.78248718
90Leukocyte transendothelial migration_Homo sapiens_hsa046700.77600319
91Staphylococcus aureus infection_Homo sapiens_hsa051500.77231506
92Choline metabolism in cancer_Homo sapiens_hsa052310.76218473
93Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.76111982
94Synaptic vesicle cycle_Homo sapiens_hsa047210.74892520
95Thyroid hormone synthesis_Homo sapiens_hsa049180.74569095
96Collecting duct acid secretion_Homo sapiens_hsa049660.73667952
97Olfactory transduction_Homo sapiens_hsa047400.73032962
98Insulin resistance_Homo sapiens_hsa049310.72924272
99Measles_Homo sapiens_hsa051620.71922909
100Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.71800867
101Phospholipase D signaling pathway_Homo sapiens_hsa040720.71731572
102Melanoma_Homo sapiens_hsa052180.71372339
103Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.71147972
104Estrogen signaling pathway_Homo sapiens_hsa049150.70943791
105Bladder cancer_Homo sapiens_hsa052190.70590576
106Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.70577047
107Cocaine addiction_Homo sapiens_hsa050300.70408989
108NF-kappa B signaling pathway_Homo sapiens_hsa040640.68019084
109Ras signaling pathway_Homo sapiens_hsa040140.67522839
110Toxoplasmosis_Homo sapiens_hsa051450.66176713
111Regulation of autophagy_Homo sapiens_hsa041400.65859244
112Dopaminergic synapse_Homo sapiens_hsa047280.65753771
113Neuroactive ligand-receptor interaction_Homo sapiens_hsa040800.65643784
114Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.65188003
115Pancreatic secretion_Homo sapiens_hsa049720.65131016
116Non-small cell lung cancer_Homo sapiens_hsa052230.64223240
117Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.63037654
118Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.62092989
119Carbohydrate digestion and absorption_Homo sapiens_hsa049730.62050299
120Ether lipid metabolism_Homo sapiens_hsa005650.61372204
121Osteoclast differentiation_Homo sapiens_hsa043800.61030556
122Glioma_Homo sapiens_hsa052140.60162384
123MAPK signaling pathway_Homo sapiens_hsa040100.59727050
124Rheumatoid arthritis_Homo sapiens_hsa053230.59044181
125Transcriptional misregulation in cancer_Homo sapiens_hsa052020.58588725
126HIF-1 signaling pathway_Homo sapiens_hsa040660.58187989
127Type II diabetes mellitus_Homo sapiens_hsa049300.57981682
128Toll-like receptor signaling pathway_Homo sapiens_hsa046200.57956758
129Endocytosis_Homo sapiens_hsa041440.57386298
130ErbB signaling pathway_Homo sapiens_hsa040120.57317417
131Hematopoietic cell lineage_Homo sapiens_hsa046400.56089274
132cAMP signaling pathway_Homo sapiens_hsa040240.55392545
133Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.54600462
134Insulin secretion_Homo sapiens_hsa049110.53373473
135GABAergic synapse_Homo sapiens_hsa047270.53034762
136Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52624453
137MicroRNAs in cancer_Homo sapiens_hsa052060.50855370
138TGF-beta signaling pathway_Homo sapiens_hsa043500.50405803
139Ribosome_Homo sapiens_hsa030100.49845519
140Wnt signaling pathway_Homo sapiens_hsa043100.49839819
141Salmonella infection_Homo sapiens_hsa051320.49783038
142Hepatitis B_Homo sapiens_hsa051610.47390391
143Axon guidance_Homo sapiens_hsa043600.44647906

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