CSK

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1positive regulation of gamma-delta T cell activation (GO:0046645)5.18136721
2antigen processing and presentation of endogenous peptide antigen (GO:0002483)5.11957260
3antigen processing and presentation of endogenous peptide antigen via MHC class I (GO:0019885)5.11957260
4antigen processing and presentation of endogenous antigen (GO:0019883)5.04802768
5positive regulation by symbiont of host defense response (GO:0052509)5.03864162
6modulation by symbiont of host defense response (GO:0052031)5.03864162
7modulation by organism of immune response of other organism involved in symbiotic interaction (GO:005.03864162
8modulation by organism of defense response of other organism involved in symbiotic interaction (GO:05.03864162
9positive regulation by organism of defense response of other organism involved in symbiotic interact5.03864162
10modulation by symbiont of host immune response (GO:0052553)5.03864162
11regulation of gamma-delta T cell differentiation (GO:0045586)4.55666380
12detection of bacterium (GO:0016045)4.48524138
13detection of other organism (GO:0098543)4.45137899
14neutrophil activation involved in immune response (GO:0002283)4.18639706
15macrophage activation involved in immune response (GO:0002281)4.08372534
16positive regulation of histone deacetylation (GO:0031065)4.08272149
17response to peptidoglycan (GO:0032494)4.04932310
18regulation of gamma-delta T cell activation (GO:0046643)4.04567969
19B cell receptor signaling pathway (GO:0050853)3.96362494
20positive regulation of B cell differentiation (GO:0045579)3.93243925
21interferon-gamma production (GO:0032609)3.89674264
22positive thymic T cell selection (GO:0045059)3.84590723
23protein localization to kinetochore (GO:0034501)3.80926899
24regulation of B cell receptor signaling pathway (GO:0050855)3.77684751
25regulation of B cell differentiation (GO:0045577)3.75236392
26negative regulation of interleukin-12 production (GO:0032695)3.75024399
27positive regulation of protein deacetylation (GO:0090312)3.73858864
28negative regulation of lymphocyte mediated immunity (GO:0002707)3.69676924
29detection of external biotic stimulus (GO:0098581)3.53863184
30type I interferon signaling pathway (GO:0060337)3.52449969
31cellular response to type I interferon (GO:0071357)3.52449969
32response to type I interferon (GO:0034340)3.50293883
33response to muramyl dipeptide (GO:0032495)3.49155095
34positive regulation of antigen receptor-mediated signaling pathway (GO:0050857)3.47931876
35positive regulation of type I interferon-mediated signaling pathway (GO:0060340)3.44987970
36negative regulation of leukocyte mediated immunity (GO:0002704)3.43627002
37respiratory burst (GO:0045730)3.41285838
38polyketide metabolic process (GO:0030638)3.41237542
39doxorubicin metabolic process (GO:0044598)3.41237542
40daunorubicin metabolic process (GO:0044597)3.41237542
41cellular extravasation (GO:0045123)3.39768767
42response to immune response of other organism involved in symbiotic interaction (GO:0052564)3.37283181
43response to host immune response (GO:0052572)3.37283181
44negative regulation of T cell mediated immunity (GO:0002710)3.36786987
45cellular response to interleukin-15 (GO:0071350)3.35340517
46germinal center formation (GO:0002467)3.33536342
47natural killer cell differentiation (GO:0001779)3.32889714
48regulation of T cell tolerance induction (GO:0002664)3.29749987
49negative regulation of leukocyte mediated cytotoxicity (GO:0001911)3.27131627
50negative regulation of cell killing (GO:0031342)3.27131627
51regulation of mast cell degranulation (GO:0043304)3.25231912
52thymic T cell selection (GO:0045061)3.21204441
53negative thymic T cell selection (GO:0045060)3.20853813
54immunoglobulin mediated immune response (GO:0016064)3.20538897
55response to host (GO:0075136)3.20227794
56response to host defenses (GO:0052200)3.20227794
57response to defenses of other organism involved in symbiotic interaction (GO:0052173)3.20227794
58defense response to protozoan (GO:0042832)3.18196540
59negative T cell selection (GO:0043383)3.17384402
60regulation of dendritic cell antigen processing and presentation (GO:0002604)3.13154387
61positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770)3.13133416
62myeloid cell activation involved in immune response (GO:0002275)3.11302509
63neutrophil activation (GO:0042119)3.11127678
64detection of biotic stimulus (GO:0009595)3.08740230
65B cell homeostasis (GO:0001782)3.04931054
66regulation of alpha-beta T cell proliferation (GO:0046640)3.04825051
67protein localization to chromosome, centromeric region (GO:0071459)3.03606210
68heterochromatin organization (GO:0070828)3.03097784
69regulation of tolerance induction (GO:0002643)3.00788652
70DNA unwinding involved in DNA replication (GO:0006268)3.00644559
71T cell selection (GO:0045058)3.00411373
72regulation of myeloid leukocyte mediated immunity (GO:0002886)2.99215782
73regulation of leukocyte degranulation (GO:0043300)2.99113851
74regulation of natural killer cell mediated cytotoxicity (GO:0042269)2.98605984
75regulation of natural killer cell mediated immunity (GO:0002715)2.98605984
76mRNA stabilization (GO:0048255)2.98298346
77RNA stabilization (GO:0043489)2.98298346
78response to protozoan (GO:0001562)2.95715510
79regulation of interleukin-12 biosynthetic process (GO:0045075)2.93775487
80regulation of antigen processing and presentation (GO:0002577)2.93486978
81granulocyte activation (GO:0036230)2.90514103
82regulation of mast cell activation involved in immune response (GO:0033006)2.89814658
83detection of molecule of bacterial origin (GO:0032490)2.87032381
84Arp2/3 complex-mediated actin nucleation (GO:0034314)2.86865387
85lymphocyte homeostasis (GO:0002260)2.86007929
86myeloid dendritic cell differentiation (GO:0043011)2.84697243
87negative regulation of innate immune response (GO:0045824)2.84600492
88myeloid dendritic cell activation (GO:0001773)2.84458861
89antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G2.83625992
90maternal placenta development (GO:0001893)2.83108740
91lipopolysaccharide-mediated signaling pathway (GO:0031663)2.82505864
92positive T cell selection (GO:0043368)2.81907155
93regulation of antigen processing and presentation of peptide antigen (GO:0002583)2.80989897
94regulation of T cell mediated cytotoxicity (GO:0001914)2.80936444
95pre-miRNA processing (GO:0031054)2.80054167
96positive regulation of tumor necrosis factor biosynthetic process (GO:0042535)2.78616155
97negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515)2.78068298
98regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923)2.77932497
993-UTR-mediated mRNA stabilization (GO:0070935)2.75460710
100hepatocyte apoptotic process (GO:0097284)2.74526946
101response to interleukin-15 (GO:0070672)2.73690452
102positive regulation of mast cell activation (GO:0033005)2.72890000
103megakaryocyte development (GO:0035855)2.72718676
104negative regulation of erythrocyte differentiation (GO:0045647)2.72034009
105regulation of type I interferon-mediated signaling pathway (GO:0060338)2.71739721
106positive regulation of interferon-alpha production (GO:0032727)2.71677726
107B cell mediated immunity (GO:0019724)2.70359920
108positive regulation of T cell mediated cytotoxicity (GO:0001916)2.70225943
109CD4-positive or CD8-positive, alpha-beta T cell lineage commitment (GO:0043369)2.69768189
110leukocyte aggregation (GO:0070486)2.67992366
111maintenance of protein location in nucleus (GO:0051457)2.67832952
112chromatin assembly (GO:0031497)2.67052699
113antigen processing and presentation via MHC class Ib (GO:0002475)2.66748680
114positive regulation of isotype switching (GO:0045830)2.66336506
115JAK-STAT cascade involved in growth hormone signaling pathway (GO:0060397)2.65583063
116regulation of telomere maintenance via telomerase (GO:0032210)2.65376979
117ribosomal small subunit biogenesis (GO:0042274)2.61591334
118cytidine deamination (GO:0009972)2.61236389
119cytidine metabolic process (GO:0046087)2.61236389
120cytidine catabolic process (GO:0006216)2.61236389
121mitotic sister chromatid segregation (GO:0000070)2.61164760
122viral transcription (GO:0019083)2.61047122
123regulation of interferon-beta biosynthetic process (GO:0045357)2.60075064
124natural killer cell activation (GO:0030101)2.58682339
125regulation of interleukin-2 biosynthetic process (GO:0045076)2.58418218
126tolerance induction (GO:0002507)2.58229261
127nuclear pore complex assembly (GO:0051292)2.58149943
128T cell migration (GO:0072678)2.57027957
129* antigen receptor-mediated signaling pathway (GO:0050851)2.56161212
130NIK/NF-kappaB signaling (GO:0038061)2.55347826
131regulation of antigen receptor-mediated signaling pathway (GO:0050854)2.54639185
132positive regulation of interleukin-2 production (GO:0032743)2.52033628
133positive regulation of interleukin-2 biosynthetic process (GO:0045086)2.51568851
134ribosomal small subunit assembly (GO:0000028)2.51345832
135T cell homeostasis (GO:0043029)2.50767425
136sister chromatid segregation (GO:0000819)2.49443288
137histone H4-K12 acetylation (GO:0043983)2.49405068
138response to laminar fluid shear stress (GO:0034616)2.48783247
139regulation of MHC class I biosynthetic process (GO:0045343)2.47883521
140adaptation of signaling pathway (GO:0023058)2.46524856
141positive regulation of gene expression, epigenetic (GO:0045815)2.45248687
142cellular response to interleukin-4 (GO:0071353)2.45204093
143negative regulation of telomerase activity (GO:0051974)2.44277865
144DNA duplex unwinding (GO:0032508)2.43373785
145regulation of erythrocyte differentiation (GO:0045646)2.43288238
146rRNA transcription (GO:0009303)2.43043382
147histone H4-K5 acetylation (GO:0043981)2.41067467
148histone H4-K8 acetylation (GO:0043982)2.41067467
149translational termination (GO:0006415)2.40390685
150DNA geometric change (GO:0032392)2.39681918
151negative regulation of cell cycle G2/M phase transition (GO:1902750)2.39544958
152cellular response to zinc ion (GO:0071294)2.39093911
153pentose-phosphate shunt (GO:0006098)2.38775684
154regulation of translation in response to stress (GO:0043555)2.38681643
155negative regulation of histone methylation (GO:0031061)2.37255473
156regulation of response to interferon-gamma (GO:0060330)2.35908919
157establishment of endothelial barrier (GO:0061028)2.35141650
158regulation of nuclear cell cycle DNA replication (GO:0033262)2.34944205
159regulation of necroptotic process (GO:0060544)2.34937357
160interferon-gamma-mediated signaling pathway (GO:0060333)2.34876635
161histone H4-K16 acetylation (GO:0043984)2.34771869
162endothelial tube morphogenesis (GO:0061154)2.34320686
163morphogenesis of an endothelium (GO:0003159)2.34320686

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.43846773
2* MYC_22102868_ChIP-Seq_BL_Human3.81589624
3BP1_19119308_ChIP-ChIP_Hs578T_Human3.32225214
4IRF8_22096565_ChIP-ChIP_GC-B_Human3.08014557
5EGR1_19374776_ChIP-ChIP_THP-1_Human2.93582732
6FOXM1_23109430_ChIP-Seq_U2OS_Human2.71537130
7* VDR_21846776_ChIP-Seq_THP-1_Human2.69802992
8STAT6_20620947_ChIP-Seq_CD4_POS_T_Human2.54171103
9SCL_19346495_ChIP-Seq_HPC-7_Human2.32045548
10IRF8_22096565_ChIP-ChIP_GC-B_Mouse2.30812351
11* EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse2.27252577
12* MECOM_23826213_ChIP-Seq_KASUMI_Mouse2.25507155
13SPI1_22096565_ChIP-ChIP_GC-B_Mouse2.22804126
14* TCF7_22412390_ChIP-Seq_EML_Mouse2.18945317
15FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.17908760
16* NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse2.16940034
17MAF_26560356_Chip-Seq_TH1_Human2.15673637
18IRF8_21731497_ChIP-ChIP_J774_Mouse1.99108685
19VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.99090388
20* UTX_26944678_Chip-Seq_JUKART_Human1.95191962
21E2F4_17652178_ChIP-ChIP_JURKAT_Human1.91999389
22SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse1.91929046
23E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human1.89050064
24* MYB_26560356_Chip-Seq_TH2_Human1.86148086
25* MYB_26560356_Chip-Seq_TH1_Human1.84925434
26RUNX1_20887958_ChIP-Seq_HPC-7_Mouse1.77601952
27KDM2B_26808549_Chip-Seq_SIL-ALL_Human1.75749653
28FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse1.75654637
29* KDM2B_26808549_Chip-Seq_HPB-ALL_Human1.73460939
30MYB_21317192_ChIP-Seq_ERMYB_Mouse1.72364588
31ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.70587545
32NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human1.70390320
33* ELK3_25401928_ChIP-Seq_HUVEC_Human1.69270327
34* RUNX1_22412390_ChIP-Seq_EML_Mouse1.69091641
35* KDM2B_26808549_Chip-Seq_SUP-B15_Human1.67855454
36* SPI1_23547873_ChIP-Seq_NB4_Human1.65393427
37FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human1.64664685
38* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.64610723
39* BRD4_27068464_Chip-Seq_AML-cells_Mouse1.64489625
40IRF8_27001747_Chip-Seq_BMDM_Mouse1.63495596
41* KDM2B_26808549_Chip-Seq_DND41_Human1.61319560
42* VDR_24763502_ChIP-Seq_THP-1_Human1.60151171
43* NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.58479973
44CIITA_25753668_ChIP-Seq_RAJI_Human1.56177845
45STAT4_19710469_ChIP-ChIP_TH1__Mouse1.54832374
46SOX9_22984422_ChIP-ChIP_TESTIS_Rat1.53439012
47* MAF_26560356_Chip-Seq_TH2_Human1.49436604
48TP63_19390658_ChIP-ChIP_HaCaT_Human1.48490948
49TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48298537
50KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.47415669
51KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.47415669
52KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.47415669
53IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.46483230
54TAL1_20887958_ChIP-Seq_HPC-7_Mouse1.45178920
55NOTCH1_17114293_ChIP-ChIP_T-ALL_Human1.44948462
56STAT6_21828071_ChIP-Seq_BEAS2B_Human1.44839005
57NOTCH1_21737748_ChIP-Seq_TLL_Human1.44444747
58STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.42930943
59MYC_18555785_ChIP-Seq_MESCs_Mouse1.40937667
60STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.40529728
61* RUNX_20019798_ChIP-Seq_JUKART_Human1.40257453
62PU.1_20513432_ChIP-Seq_MACROPHAGES_Mouse1.34846378
63SPI1_23127762_ChIP-Seq_K562_Human1.32849296
64PU.1_20513432_ChIP-Seq_Bcells_Mouse1.32191907
65FLI1_20887958_ChIP-Seq_HPC-7_Mouse1.30532229
66NCOR1_26117541_ChIP-Seq_K562_Human1.28839093
67MYC_19079543_ChIP-ChIP_MESCs_Mouse1.25351282
68* LXR_22292898_ChIP-Seq_THP-1_Human1.25236797
69BCL6_27268052_Chip-Seq_Bcells_Human1.25169250
70SFPI1_20887958_ChIP-Seq_HPC-7_Mouse1.24769590
71PU.1_20176806_ChIP-Seq_MACROPHAGES_Mouse1.22222140
72* BCOR_27268052_Chip-Seq_Bcells_Human1.21294077
73STAT3_1855785_ChIP-Seq_MESCs_Mouse1.21229182
74* GATA1_22383799_ChIP-Seq_G1ME_Mouse1.19631899
75GATA2_21571218_ChIP-Seq_MEGAKARYOCYTES_Human1.17654510
76SMAD1_18555785_ChIP-Seq_MESCs_Mouse1.17164070
77* SA1_27219007_Chip-Seq_ERYTHROID_Human1.17044281
78P68_20966046_ChIP-Seq_HELA_Human1.16444718
79PPARG_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.12894483
80RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.11183881
81* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse1.11176398
82SPI1_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse1.10900809
83GATA2_22383799_ChIP-Seq_G1ME_Mouse1.10689337
84POU5F1_18700969_ChIP-ChIP_MESCs_Mouse1.06692611
85KDM5A_27292631_Chip-Seq_BREAST_Human1.03637069
86CEBPB_20513432_ChIP-Seq_MACROPHAGES_Mouse1.03509668
87MEIS1_20887958_ChIP-Seq_HPC-7_Mouse1.02245252
88FOXP3_21729870_ChIP-Seq_TREG_Human1.01567954
89PU_27001747_Chip-Seq_BMDM_Mouse1.01563148
90XRN2_22483619_ChIP-Seq_HELA_Human1.01419631
91GATA3_27048872_Chip-Seq_THYMUS_Human1.01370898
92KLF4_18358816_ChIP-ChIP_MESCs_Mouse1.01049350
93GATA2_20887958_ChIP-Seq_HPC-7_Mouse1.00402021
94TET1_21451524_ChIP-Seq_MESCs_Mouse0.99918221
95MYC_19030024_ChIP-ChIP_MESCs_Mouse0.99124761
96CEBPA_20513432_ChIP-Seq_MACROPHAGES_Mouse0.98427251
97ELF1_17652178_ChIP-ChIP_JURKAT_Human0.98043719
98KDM2B_26808549_Chip-Seq_K562_Human0.96732739
99SRY_22984422_ChIP-ChIP_TESTIS_Rat0.95759007
100IKZF1_21737484_ChIP-ChIP_HCT116_Human0.95673454
101* RUNX1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.95334616
102KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.94864136
103GATA1_19941826_ChIP-Seq_K562_Human0.94851478
104GFI1B_20887958_ChIP-Seq_HPC-7_Mouse0.94724232
105ERG_20887958_ChIP-Seq_HPC-7_Mouse0.94623284
106* RACK7_27058665_Chip-Seq_MCF-7_Human0.94499497
107ELF1_20517297_ChIP-Seq_JURKAT_Human0.94133689
108MYC_18358816_ChIP-ChIP_MESCs_Mouse0.93422304
109CEBPB_20176806_ChIP-Seq_THIOMACROPHAGE_Mouse0.92106029
110SMC4_20622854_ChIP-Seq_HELA_Human0.91920985
111E2F1_21310950_ChIP-Seq_MCF-7_Human0.91830077
112VDR_24787735_ChIP-Seq_THP-1_Human0.90995238
113LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.90876054
114* CTCF_26484167_Chip-Seq_Bcells_Mouse0.89222803
115CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human0.88861295
116KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.88501909
117THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.88276986
118CTCF_21964334_Chip-Seq_Bcells_Human0.87919188
119* KDM2B_26808549_Chip-Seq_JURKAT_Human0.87804742
120LMO2_20887958_ChIP-Seq_HPC-7_Mouse0.87798354
121CTCF_21964334_ChIP-Seq_BJAB-B_Human0.87700002
122* KLF4_18555785_ChIP-Seq_MESCs_Mouse0.87075312
123Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse0.86621194
124NFE2L2_22581777_ChIP-Seq_LYMPHOBLASTOID_Human0.85912136
125DACH1_20351289_ChIP-Seq_MDA-MB-231_Human0.85658094
126GATA1_19941827_ChIP-Seq_MEL_Mouse0.85122606
127* PPARA_22158963_ChIP-Seq_LIVER_Mouse0.84939382
128HIF1A_21447827_ChIP-Seq_MCF-7_Human0.84343390
129TFEB_21752829_ChIP-Seq_HELA_Human0.84212732
130CTCF_27219007_Chip-Seq_ERYTHROID_Human0.84208432
131CEBPB_20176806_ChIP-Seq_MACROPHAGES_Mouse0.83929326

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0001835_abnormal_antigen_presentation3.34403947
2MP0001800_abnormal_humoral_immune3.00757026
3MP0000685_abnormal_immune_system2.93215456
4MP0002396_abnormal_hematopoietic_system2.88343459
5MP0001790_abnormal_immune_system2.76715926
6MP0005387_immune_system_phenotype2.76715926
7MP0003303_peritoneal_inflammation2.59142475
8MP0003763_abnormal_thymus_physiology2.50285316
9MP0002452_abnormal_antigen_presenting2.40843674
10MP0005671_abnormal_response_to2.39339428
11MP0003436_decreased_susceptibility_to2.37812364
12* MP0002398_abnormal_bone_marrow2.36231484
13MP0010352_gastrointestinal_tract_polyps2.32294433
14MP0005000_abnormal_immune_tolerance2.27299929
15MP0002723_abnormal_immune_serum2.21717855
16* MP0002420_abnormal_adaptive_immunity2.21566634
17* MP0001819_abnormal_immune_cell2.18428867
18MP0000689_abnormal_spleen_morphology2.15724136
19MP0006082_CNS_inflammation2.08300187
20* MP0000716_abnormal_immune_system2.05364048
21MP0003300_gastrointestinal_ulcer2.05061178
22* MP0002722_abnormal_immune_system2.02004106
23MP0005451_abnormal_body_composition1.98619209
24MP0002405_respiratory_system_inflammati1.95574440
25MP0008057_abnormal_DNA_replication1.94027528
26MP0008260_abnormal_autophagy1.91342974
27* MP0005025_abnormal_response_to1.89827182
28MP0004808_abnormal_hematopoietic_stem1.89744909
29MP0009333_abnormal_splenocyte_physiolog1.88138643
30MP0003705_abnormal_hypodermis_morpholog1.87186706
31* MP0002429_abnormal_blood_cell1.83843197
32MP0000703_abnormal_thymus_morphology1.78814207
33MP0005075_abnormal_melanosome_morpholog1.78495869
34MP0009785_altered_susceptibility_to1.73230293
35MP0010155_abnormal_intestine_physiology1.71012135
36MP0002254_reproductive_system_inflammat1.70952461
37MP0009278_abnormal_bone_marrow1.69350946
38MP0000490_abnormal_crypts_of1.64805299
39MP0005464_abnormal_platelet_physiology1.63896510
40MP0005058_abnormal_lysosome_morphology1.61993814
41MP0001873_stomach_inflammation1.61301604
42MP0004957_abnormal_blastocyst_morpholog1.60918239
43MP0002419_abnormal_innate_immunity1.55952968
44MP0002166_altered_tumor_susceptibility1.55120865
45MP0004947_skin_inflammation1.51417132
46MP0003077_abnormal_cell_cycle1.49464808
47MP0004381_abnormal_hair_follicle1.49391470
48MP0005397_hematopoietic_system_phenotyp1.49073894
49MP0001545_abnormal_hematopoietic_system1.49073894
50MP0004264_abnormal_extraembryonic_tissu1.45897522
51MP0000465_gastrointestinal_hemorrhage1.35805305
52* MP0001845_abnormal_inflammatory_respons1.35517789
53MP0001853_heart_inflammation1.33160826
54MP0002019_abnormal_tumor_incidence1.30639589
55MP0008961_abnormal_basal_metabolism1.30570169
56MP0010094_abnormal_chromosome_stability1.26602441
57MP0002148_abnormal_hypersensitivity_rea1.26553744
58MP0003111_abnormal_nucleus_morphology1.23428420
59MP0000858_altered_metastatic_potential1.22739671
60MP0003191_abnormal_cellular_cholesterol1.21465044
61MP0003693_abnormal_embryo_hatching1.20881298
62MP0004510_myositis1.20448549
63MP0001851_eye_inflammation1.18719463
64MP0002998_abnormal_bone_remodeling1.16525971
65MP0000350_abnormal_cell_proliferation1.15746609
66MP0003866_abnormal_defecation1.15114073
67MP0003828_pulmonary_edema1.13535999
68MP0005076_abnormal_cell_differentiation1.12746931
69MP0005023_abnormal_wound_healing1.11240715
70MP0003448_altered_tumor_morphology1.10011822
71MP0002006_tumorigenesis1.08369239
72MP0003183_abnormal_peptide_metabolism1.07700354
73MP0009840_abnormal_foam_cell1.06061393
74MP0003566_abnormal_cell_adhesion1.02812463
75MP0010307_abnormal_tumor_latency1.02457192
76MP0005310_abnormal_salivary_gland1.01451711
77MP0008469_abnormal_protein_level1.00591735
78MP0002132_abnormal_respiratory_system0.99351213
79MP0002138_abnormal_hepatobiliary_system0.97290260
80MP0001663_abnormal_digestive_system0.95492413
81MP0000609_abnormal_liver_physiology0.93306859
82* MP0000313_abnormal_cell_death0.92185740
83MP0008007_abnormal_cellular_replicative0.91419343
84MP0003172_abnormal_lysosome_physiology0.91340487
85MP0003011_delayed_dark_adaptation0.91292870
86MP0002933_joint_inflammation0.91027715
87MP0009764_decreased_sensitivity_to0.90396900
88MP0001849_ear_inflammation0.90149497
89* MP0002088_abnormal_embryonic_growth/wei0.88972071
90* MP0003984_embryonic_growth_retardation0.88727283
91* MP0005380_embryogenesis_phenotype0.87394670
92* MP0001672_abnormal_embryogenesis/_devel0.87394670
93* MP0002086_abnormal_extraembryonic_tissu0.85467820
94MP0003075_altered_response_to0.85394313
95MP0001533_abnormal_skeleton_physiology0.85286711
96MP0005166_decreased_susceptibility_to0.85244542
97MP0000598_abnormal_liver_morphology0.82836261
98MP0004185_abnormal_adipocyte_glucose0.79099968
99MP0004883_abnormal_blood_vessel0.77755897
100MP0000477_abnormal_intestine_morphology0.76164460
101* MP0001730_embryonic_growth_arrest0.74783670
102MP0005390_skeleton_phenotype0.74242548
103MP0002970_abnormal_white_adipose0.73869889
104MP0002009_preneoplasia0.73638576
105MP0009763_increased_sensitivity_to0.72969283
106MP0005257_abnormal_intraocular_pressure0.71546963
107MP0002277_abnormal_respiratory_mucosa0.71213841
108MP0000604_amyloidosis0.71205099
109MP0000343_altered_response_to0.69640446
110MP0002080_prenatal_lethality0.68305278
111MP0000015_abnormal_ear_pigmentation0.67463553
112MP0003724_increased_susceptibility_to0.66735434
113MP0004197_abnormal_fetal_growth/weight/0.66731999
114MP0001348_abnormal_lacrimal_gland0.65610092
115MP0008874_decreased_physiological_sensi0.63692049
116MP0008770_decreased_survivor_rate0.62501153
117MP0003795_abnormal_bone_structure0.62198788
118MP0003091_abnormal_cell_migration0.62130920
119MP0003453_abnormal_keratinocyte_physiol0.61556796
120MP0005174_abnormal_tail_pigmentation0.61083905
121MP0005381_digestive/alimentary_phenotyp0.61040644
122MP0003045_fibrosis0.60296375
123MP0002877_abnormal_melanocyte_morpholog0.59246676
124MP0008873_increased_physiological_sensi0.59192751
125MP0000249_abnormal_blood_vessel0.58722344
126MP0003690_abnormal_glial_cell0.56913790
127MP0004858_abnormal_nervous_system0.54046690
128MP0009765_abnormal_xenobiotic_induced0.50301856
129MP0005621_abnormal_cell_physiology0.50223646

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of macrophages (HP:0004311)4.73593727
2Cellulitis (HP:0100658)4.07816527
3Agammaglobulinemia (HP:0004432)3.99818978
4Recurrent viral infections (HP:0004429)3.95989216
5Orchitis (HP:0100796)3.85747223
6Recurrent bronchitis (HP:0002837)3.73929699
7Nasal polyposis (HP:0100582)3.69107441
8IgM deficiency (HP:0002850)3.67278572
9Abnormal delayed hypersensitivity skin test (HP:0002963)3.64491584
10Panhypogammaglobulinemia (HP:0003139)3.59396271
11Optic neuritis (HP:0100653)3.57708552
12Retrobulbar optic neuritis (HP:0100654)3.57708552
13Gastrointestinal infarctions (HP:0005244)3.54072344
14Colitis (HP:0002583)3.44168739
15Gastrointestinal inflammation (HP:0004386)3.41229608
16Inflammation of the large intestine (HP:0002037)3.38811874
17Recurrent fungal infections (HP:0002841)3.33579124
18Multiple enchondromatosis (HP:0005701)3.28859368
19Abnormality of the nasal mucosa (HP:0000433)3.28449619
20Stomatitis (HP:0010280)3.26788508
21Elevated erythrocyte sedimentation rate (HP:0003565)3.23793129
22Verrucae (HP:0200043)3.20353278
23Papilloma (HP:0012740)3.20353278
24Combined immunodeficiency (HP:0005387)3.10522083
25Urticaria (HP:0001025)3.08790278
26T lymphocytopenia (HP:0005403)3.06977654
27Abnormality of T cells (HP:0002843)3.03236760
28Gingivitis (HP:0000230)3.02338314
29Eczematoid dermatitis (HP:0000976)3.00548748
30Chronic otitis media (HP:0000389)2.94755432
31Abnormality of T cell physiology (HP:0011840)2.91843608
32Abnormality of T cell number (HP:0011839)2.90411390
33Meningitis (HP:0001287)2.90361531
34Hypochromic anemia (HP:0001931)2.89444674
35Hypochromic microcytic anemia (HP:0004840)2.79912528
36Recurrent abscess formation (HP:0002722)2.78320152
37Spontaneous hematomas (HP:0007420)2.74397620
38Keratoconjunctivitis sicca (HP:0001097)2.62146688
39Petechiae (HP:0000967)2.58290921
40Increased IgM level (HP:0003496)2.57813802
41Abnormality of the fingertips (HP:0001211)2.57003620
42Chronic mucocutaneous candidiasis (HP:0002728)2.55702019
43Recurrent cutaneous fungal infections (HP:0011370)2.55702019
44Pustule (HP:0200039)2.54136894
45Recurrent bacterial skin infections (HP:0005406)2.53167167
46Myositis (HP:0100614)2.50343426
47Thrombocytosis (HP:0001894)2.47502874
48Gastrointestinal stroma tumor (HP:0100723)2.46952241
49Hemoptysis (HP:0002105)2.46225944
50Lymphopenia (HP:0001888)2.43410395
51Abnormality of cells of the lymphoid lineage (HP:0012140)2.41186507
52Abnormality of B cell number (HP:0010975)2.41147135
53B lymphocytopenia (HP:0010976)2.41147135
54Autoimmune thrombocytopenia (HP:0001973)2.40260384
55Vasculitis (HP:0002633)2.39329699
56Emphysema (HP:0002097)2.38552405
57Purpura (HP:0000979)2.38135038
58Prolonged bleeding time (HP:0003010)2.33192904
59Recurrent sinusitis (HP:0011108)2.32934736
60Keratoconjunctivitis (HP:0001096)2.32860049
61Bilateral microphthalmos (HP:0007633)2.32730388
62Chest pain (HP:0100749)2.31038931
63Parkinsonism with favorable response to dopaminergic medication (HP:0002548)2.27490742
64Arterial thrombosis (HP:0004420)2.25146452
65Osteomyelitis (HP:0002754)2.23179757
66Pulmonary embolism (HP:0002204)2.22109993
67Hypergammaglobulinemia (HP:0010702)2.21696126
68Cheilitis (HP:0100825)2.16271647
69Recurrent lower respiratory tract infections (HP:0002783)2.16081057
70Recurrent skin infections (HP:0001581)2.15954233
71Increased IgE level (HP:0003212)2.14070808
72Increased cerebral lipofuscin (HP:0011813)2.13141215
73Hypertensive crisis (HP:0100735)2.13109433
74Gingival bleeding (HP:0000225)2.12890000
75Recurrent pneumonia (HP:0006532)2.11663262
76Impaired platelet aggregation (HP:0003540)2.10953620
77Abnormal platelet function (HP:0011869)2.10953620
78Ulnar bowing (HP:0003031)2.09072966
79Slow saccadic eye movements (HP:0000514)2.08087417
80Abnormal platelet volume (HP:0011876)2.07341567
81Ependymoma (HP:0002888)2.07009091
82IgA deficiency (HP:0002720)2.04933139
83Abnormality of the peritoneum (HP:0002585)2.04741010
84Rhabdomyosarcoma (HP:0002859)2.04356723
85Epistaxis (HP:0000421)2.02886243
86Autoimmune hemolytic anemia (HP:0001890)2.01859333
87Restrictive lung disease (HP:0002091)2.00495968
88Neoplasm of striated muscle (HP:0009728)1.99604858
89Thyroiditis (HP:0100646)1.99332145
90Abnormality of the pleura (HP:0002103)1.98540383
91Premature loss of primary teeth (HP:0006323)1.98246720
92Mediastinal lymphadenopathy (HP:0100721)1.97724078
93Leukocytosis (HP:0001974)1.97616901
94Viral hepatitis (HP:0006562)1.97271956
95Basal cell carcinoma (HP:0002671)1.95577020
96Increased serum ferritin (HP:0003281)1.95249738
97Hepatosplenomegaly (HP:0001433)1.95178379
98Anorexia (HP:0002039)1.95117642
99Abnormality of liposaccharide metabolism (HP:0010968)1.94049897
100Abnormality of glycosphingolipid metabolism (HP:0004343)1.94049897
101Abnormality of glycolipid metabolism (HP:0010969)1.94049897
102Bronchitis (HP:0012387)1.93305619
103Lymphoma (HP:0002665)1.93173487
104Eosinophilia (HP:0001880)1.92892127
105Glomerulopathy (HP:0100820)1.92286929
106Episodic fever (HP:0001954)1.92011581
107Increased density of long bones (HP:0006392)1.91380246
108Loss of speech (HP:0002371)1.90357124
109Recurrent gram-negative bacterial infections (HP:0005420)1.88444171
110Dysostosis multiplex (HP:0000943)1.88002695
111Arthralgia (HP:0002829)1.87510915
112Chronic diarrhea (HP:0002028)1.87419452
113Interstitial pulmonary disease (HP:0006530)1.86444276
114Skin tags (HP:0010609)1.85915464
115Encephalitis (HP:0002383)1.85721071
116Chronic sinusitis (HP:0011109)1.85584911
117Granulocytopenia (HP:0001913)1.85022009
118Fatigue (HP:0012378)1.83911402
119Aplasia/Hypoplasia of the thymus (HP:0010515)1.83051638
120Periodontitis (HP:0000704)1.82703905
121Severe combined immunodeficiency (HP:0004430)1.82632240
122Microcytic anemia (HP:0001935)1.79315461
123IgG deficiency (HP:0004315)1.79248107
124Chronic obstructive pulmonary disease (HP:0006510)1.77505790
125Obstructive lung disease (HP:0006536)1.77505790
126Abnormality of the intervertebral disk (HP:0005108)1.77401568
127Skin ulcer (HP:0200042)1.77143216
128Abnormality of the lower motor neuron (HP:0002366)1.77004281
129Rib fusion (HP:0000902)1.75882689
130Preauricular skin tag (HP:0000384)1.75860625
131Sepsis (HP:0100806)1.72990426
132Abnormal cartilage morphology (HP:0002763)1.72361992
133Skin rash (HP:0000988)1.72204404
134Pulmonary infiltrates (HP:0002113)1.70685958
135Myocardial infarction (HP:0001658)1.70189587
136Hepatoblastoma (HP:0002884)1.70092698
137Abnormality of small intestinal villus morphology (HP:0011472)1.67495390
138Villous atrophy (HP:0011473)1.67495390

Predicted kinase interactions (KEA)

RankGene SetZ-score
1MAP4K14.54458197
2CDK124.42658731
3ERN14.06875838
4GRK63.81059074
5MAP3K103.59851403
6PRPF4B3.57428911
7EEF2K2.77871747
8STK102.77020816
9CSF1R2.67682386
10TRIB32.54244219
11SMG12.35689703
12TGFBR22.16651435
13PKN22.16195089
14BLK2.02923225
15MAP3K131.92811760
16TYK21.72767046
17ZAP701.71370554
18KIT1.57033804
19BTK1.52780079
20SIK31.51255205
21JAK31.48917051
22LRRK21.45687089
23SYK1.42973597
24MATK1.40207384
25FGFR31.34307118
26TBK11.29745881
27ITK1.28877571
28IRAK31.21357333
29TAOK21.17699853
30FGR1.16816294
31MAP2K31.15517409
32HCK1.12427561
33FGFR41.12393713
34GRK51.11979636
35NEK21.11486320
36CDK41.11081831
37SIK21.09359867
38MAP3K11.07179236
39ICK1.05787949
40PIM11.05387982
41TXK1.05141984
42ALK1.03299478
43HIPK21.02463472
44IKBKB1.01915313
45KSR21.00883379
46LCK0.95861023
47MAPK70.95806999
48TESK20.94149499
49IKBKE0.90762270
50CDC42BPA0.88924010
51JAK10.88820506
52NME20.85024967
53GRK10.84585070
54CLK10.83480445
55RPS6KB20.83396907
56MAP3K70.82935136
57PAK40.82399288
58FLT30.81710367
59PDPK10.80823902
60MAP3K140.80661807
61PTK60.79445864
62RIPK10.77119315
63LYN0.76620674
64TAOK30.76300760
65RPS6KA40.75731209
66SIK10.75314264
67CDK70.75198396
68IRAK20.72122942
69TYRO30.70454571
70CDC70.67236821
71PRKD20.65910735
72MAP3K80.65353647
73* CSK0.64827446
74STK40.64207711
75JAK20.63678094
76PRKG20.63450676
77TAOK10.62730606
78ADRBK20.62554306
79TNK20.62127505
80EPHB10.61560030
81MARK20.61213723
82PIM20.60824611
83SCYL20.60801430
84CHUK0.60396901
85TEC0.60264485
86CDK60.60131562
87CAMKK10.59523501
88MAP2K20.57695388
89IRAK40.57238534
90RPS6KC10.56936976
91RPS6KL10.56936976
92MARK30.55812607
93TTK0.55386205
94MAPK40.55175422
95YES10.52605927
96PASK0.52237959
97MOS0.51940166
98MTOR0.51627648
99PRKCH0.50665510
100IRAK10.50112294
101FES0.49827403
102MAP3K110.49473748
103BMX0.49429321
104BMPR20.49042275
105FYN0.48253555
106NLK0.47264259
107GRK70.46765064
108MAPK110.46395082
109MAPK120.46244688
110ARAF0.42574268
111CDK190.42467882
112CHEK10.41489571
113CAMK40.41314735
114MAPKAPK20.40793186
115RIPK40.39507876
116KDR0.39223860
117RET0.38214871
118RPS6KA20.38141685
119MAP3K30.37097664
120PDK10.34871455
121TTN0.34779728
122EGFR0.33191272
123PRKCQ0.32336276
124DYRK1B0.31844061
125TGFBR10.31791422
126SGK30.31208065
127RPS6KA60.31172746
128STK30.30246011
129RAF10.29002274

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary immunodeficiency_Homo sapiens_hsa053403.95591124
2B cell receptor signaling pathway_Homo sapiens_hsa046623.11933813
3Graft-versus-host disease_Homo sapiens_hsa053322.64972822
4Autoimmune thyroid disease_Homo sapiens_hsa053202.62007102
5NF-kappa B signaling pathway_Homo sapiens_hsa040642.16474540
6Antigen processing and presentation_Homo sapiens_hsa046122.00739246
7Leishmaniasis_Homo sapiens_hsa051401.98559496
8Type I diabetes mellitus_Homo sapiens_hsa049401.96555222
9DNA replication_Homo sapiens_hsa030301.92685075
10Fc gamma R-mediated phagocytosis_Homo sapiens_hsa046661.92660230
11Intestinal immune network for IgA production_Homo sapiens_hsa046721.86913159
12Fc epsilon RI signaling pathway_Homo sapiens_hsa046641.86570716
13T cell receptor signaling pathway_Homo sapiens_hsa046601.84168503
14Asthma_Homo sapiens_hsa053101.80643431
15Acute myeloid leukemia_Homo sapiens_hsa052211.78811417
16Osteoclast differentiation_Homo sapiens_hsa043801.76619038
17Measles_Homo sapiens_hsa051621.74120766
18Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046501.70320865
19Hematopoietic cell lineage_Homo sapiens_hsa046401.69161287
20Herpes simplex infection_Homo sapiens_hsa051681.58575653
21RIG-I-like receptor signaling pathway_Homo sapiens_hsa046221.55321154
22Chronic myeloid leukemia_Homo sapiens_hsa052201.54292064
23Base excision repair_Homo sapiens_hsa034101.51669031
24Ribosome_Homo sapiens_hsa030101.50373454
25Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.43969279
26Staphylococcus aureus infection_Homo sapiens_hsa051501.38927588
27Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.35430564
28Apoptosis_Homo sapiens_hsa042101.33328553
29Mismatch repair_Homo sapiens_hsa034301.31375876
30Jak-STAT signaling pathway_Homo sapiens_hsa046301.28512193
31Toxoplasmosis_Homo sapiens_hsa051451.27634276
32Non-small cell lung cancer_Homo sapiens_hsa052231.25910527
33One carbon pool by folate_Homo sapiens_hsa006701.25504091
34Pancreatic cancer_Homo sapiens_hsa052121.23336832
35Leukocyte transendothelial migration_Homo sapiens_hsa046701.21171009
36Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030081.20845160
37Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051421.20519173
38Toll-like receptor signaling pathway_Homo sapiens_hsa046201.19851142
39Hepatitis B_Homo sapiens_hsa051611.18156663
40Transcriptional misregulation in cancer_Homo sapiens_hsa052021.15357831
41Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006041.14091605
42Glycosaminoglycan degradation_Homo sapiens_hsa005311.12937013
43Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.11932485
44Influenza A_Homo sapiens_hsa051641.09103658
45Shigellosis_Homo sapiens_hsa051311.05965650
46Phagosome_Homo sapiens_hsa041451.02196200
47HTLV-I infection_Homo sapiens_hsa051661.01967999
48mTOR signaling pathway_Homo sapiens_hsa041501.01152603
49Other glycan degradation_Homo sapiens_hsa005110.99790207
50Viral carcinogenesis_Homo sapiens_hsa052030.99211157
51Platelet activation_Homo sapiens_hsa046110.98965283
52Tuberculosis_Homo sapiens_hsa051520.98951412
53Viral myocarditis_Homo sapiens_hsa054160.98860162
54Cell cycle_Homo sapiens_hsa041100.96490003
55Chemokine signaling pathway_Homo sapiens_hsa040620.95800536
56Colorectal cancer_Homo sapiens_hsa052100.95154784
57Spliceosome_Homo sapiens_hsa030400.94749546
58Legionellosis_Homo sapiens_hsa051340.93115043
59Neurotrophin signaling pathway_Homo sapiens_hsa047220.91586822
60Rheumatoid arthritis_Homo sapiens_hsa053230.90972336
61Renal cell carcinoma_Homo sapiens_hsa052110.90199135
62Small cell lung cancer_Homo sapiens_hsa052220.88767678
63Thyroid cancer_Homo sapiens_hsa052160.87959702
64Epstein-Barr virus infection_Homo sapiens_hsa051690.85971070
65p53 signaling pathway_Homo sapiens_hsa041150.84968292
66Pertussis_Homo sapiens_hsa051330.82869830
67Pentose phosphate pathway_Homo sapiens_hsa000300.82716906
68AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.81991595
69RNA transport_Homo sapiens_hsa030130.81956963
70mRNA surveillance pathway_Homo sapiens_hsa030150.81530294
71Notch signaling pathway_Homo sapiens_hsa043300.81458009
72VEGF signaling pathway_Homo sapiens_hsa043700.80496942
73Lysine degradation_Homo sapiens_hsa003100.78641477
74MicroRNAs in cancer_Homo sapiens_hsa052060.78378844
75African trypanosomiasis_Homo sapiens_hsa051430.77652789
76Pentose and glucuronate interconversions_Homo sapiens_hsa000400.77452210
77Cytosolic DNA-sensing pathway_Homo sapiens_hsa046230.77254985
78Non-homologous end-joining_Homo sapiens_hsa034500.76403002
79Fructose and mannose metabolism_Homo sapiens_hsa000510.74514475
80Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.74242749
81Hepatitis C_Homo sapiens_hsa051600.74088279
82TNF signaling pathway_Homo sapiens_hsa046680.73801538
83Sulfur relay system_Homo sapiens_hsa041220.72577777
84Sphingolipid signaling pathway_Homo sapiens_hsa040710.71548900
85Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.70214932
86Lysosome_Homo sapiens_hsa041420.69956974
87Endocytosis_Homo sapiens_hsa041440.68108745
88NOD-like receptor signaling pathway_Homo sapiens_hsa046210.67351842
89Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.66436654
90Vitamin B6 metabolism_Homo sapiens_hsa007500.65194281
91Prolactin signaling pathway_Homo sapiens_hsa049170.64362733
92Galactose metabolism_Homo sapiens_hsa000520.64060651
93Phospholipase D signaling pathway_Homo sapiens_hsa040720.63640205
94Complement and coagulation cascades_Homo sapiens_hsa046100.63158813
95Malaria_Homo sapiens_hsa051440.62883489
96Phosphatidylinositol signaling system_Homo sapiens_hsa040700.62362701
97Bladder cancer_Homo sapiens_hsa052190.61973351
98Choline metabolism in cancer_Homo sapiens_hsa052310.61758772
99Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.61670505
100Homologous recombination_Homo sapiens_hsa034400.58913248
101Insulin resistance_Homo sapiens_hsa049310.58414923
102Carbohydrate digestion and absorption_Homo sapiens_hsa049730.57006205
103Regulation of actin cytoskeleton_Homo sapiens_hsa048100.56260634
104Prostate cancer_Homo sapiens_hsa052150.55545200
105Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.54460752
106Caffeine metabolism_Homo sapiens_hsa002320.54092334
107GnRH signaling pathway_Homo sapiens_hsa049120.54001203
108Central carbon metabolism in cancer_Homo sapiens_hsa052300.52742726
109FoxO signaling pathway_Homo sapiens_hsa040680.52291692
110HIF-1 signaling pathway_Homo sapiens_hsa040660.51914805
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.51537109
112Glioma_Homo sapiens_hsa052140.50008697
113Systemic lupus erythematosus_Homo sapiens_hsa053220.49295720
114Allograft rejection_Homo sapiens_hsa053300.49083670
115Endometrial cancer_Homo sapiens_hsa052130.49073775
116ErbB signaling pathway_Homo sapiens_hsa040120.48377323
117Proteoglycans in cancer_Homo sapiens_hsa052050.48256659
118Thyroid hormone signaling pathway_Homo sapiens_hsa049190.47541994
119Pathways in cancer_Homo sapiens_hsa052000.47419059
120Inositol phosphate metabolism_Homo sapiens_hsa005620.47323683
121Selenocompound metabolism_Homo sapiens_hsa004500.43550457
122Adipocytokine signaling pathway_Homo sapiens_hsa049200.43037254
123Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.42533005
124MAPK signaling pathway_Homo sapiens_hsa040100.42082065
125Salmonella infection_Homo sapiens_hsa051320.41570064
126Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.41164309
127Drug metabolism - other enzymes_Homo sapiens_hsa009830.40935462
128RNA degradation_Homo sapiens_hsa030180.40895918
129Insulin signaling pathway_Homo sapiens_hsa049100.39904033
130Prion diseases_Homo sapiens_hsa050200.38963759
131* Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.36673369
132Amoebiasis_Homo sapiens_hsa051460.35746159
133Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.35545752

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