CSMD2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: The protein encoded by this gene is thought to be involved in the control of complement. Defects in this gene have been associated with schizophrenia. This gene may act as a tumor suppressor for colorectal cancer. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1presynaptic membrane assembly (GO:0097105)5.75953911
2postsynaptic membrane organization (GO:0001941)5.55316607
3neuron cell-cell adhesion (GO:0007158)5.27561453
4positive regulation of excitatory postsynaptic membrane potential (GO:2000463)5.24312927
5neuronal action potential propagation (GO:0019227)5.11599532
6presynaptic membrane organization (GO:0097090)5.09526158
7ionotropic glutamate receptor signaling pathway (GO:0035235)5.02867703
8regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor act4.89560742
9vocalization behavior (GO:0071625)4.76457181
10protein localization to synapse (GO:0035418)4.70398291
11regulation of short-term neuronal synaptic plasticity (GO:0048172)4.37071422
12pyrimidine nucleobase catabolic process (GO:0006208)4.26238938
13glutamate receptor signaling pathway (GO:0007215)4.26057053
14regulation of glutamate receptor signaling pathway (GO:1900449)4.20925453
15synaptic transmission, glutamatergic (GO:0035249)4.20716913
16locomotory exploration behavior (GO:0035641)4.04149981
17neurotransmitter-gated ion channel clustering (GO:0072578)3.83103467
18synaptic vesicle maturation (GO:0016188)3.81063144
19positive regulation of membrane potential (GO:0045838)3.79578952
20regulation of N-methyl-D-aspartate selective glutamate receptor activity (GO:2000310)3.77978650
21dendritic spine morphogenesis (GO:0060997)3.74587914
22behavioral response to nicotine (GO:0035095)3.74583180
23neuron-neuron synaptic transmission (GO:0007270)3.72619664
24synaptic vesicle exocytosis (GO:0016079)3.61257165
25cell migration in hindbrain (GO:0021535)3.59994132
26regulation of synaptic vesicle exocytosis (GO:2000300)3.56054566
27regulation of respiratory gaseous exchange by neurological system process (GO:0002087)3.55739917
28righting reflex (GO:0060013)3.53971345
29transmission of nerve impulse (GO:0019226)3.53858796
30membrane depolarization during action potential (GO:0086010)3.53363526
31central nervous system myelination (GO:0022010)3.51416560
32axon ensheathment in central nervous system (GO:0032291)3.51416560
33positive regulation of dendritic spine development (GO:0060999)3.50868270
34negative regulation of synaptic transmission, GABAergic (GO:0032229)3.47372423
35long-term memory (GO:0007616)3.44258431
36regulation of excitatory postsynaptic membrane potential (GO:0060079)3.43574987
37negative regulation of translation, ncRNA-mediated (GO:0040033)3.43041936
38regulation of translation, ncRNA-mediated (GO:0045974)3.43041936
39negative regulation of translation involved in gene silencing by miRNA (GO:0035278)3.43041936
40positive regulation of synaptic transmission, GABAergic (GO:0032230)3.42313225
41startle response (GO:0001964)3.39500750
42positive regulation of calcium ion-dependent exocytosis (GO:0045956)3.38785479
43exploration behavior (GO:0035640)3.34319594
44neuron recognition (GO:0008038)3.34162674
45nucleobase catabolic process (GO:0046113)3.33219076
46gamma-aminobutyric acid transport (GO:0015812)3.32967761
47positive regulation of synapse assembly (GO:0051965)3.32847255
48behavioral response to ethanol (GO:0048149)3.32114886
49glutamate secretion (GO:0014047)3.27910130
50regulation of postsynaptic membrane potential (GO:0060078)3.27340377
51regulation of neuronal synaptic plasticity (GO:0048168)3.26498950
52central nervous system projection neuron axonogenesis (GO:0021952)3.26412470
53regulation of long-term neuronal synaptic plasticity (GO:0048169)3.26121541
54L-amino acid import (GO:0043092)3.25496294
55auditory behavior (GO:0031223)3.19898251
56positive regulation of neurotransmitter secretion (GO:0001956)3.17731562
57negative regulation of cytosolic calcium ion concentration (GO:0051481)3.16499165
58gamma-aminobutyric acid signaling pathway (GO:0007214)3.13356458
59regulation of inhibitory postsynaptic membrane potential (GO:0060080)3.12719851
60negative regulation of synaptic transmission, glutamatergic (GO:0051967)3.12693190
61spinal cord development (GO:0021510)3.12620549
62regulation of synaptic vesicle transport (GO:1902803)3.12111230
63cerebral cortex radially oriented cell migration (GO:0021799)3.07648987
64G-protein coupled glutamate receptor signaling pathway (GO:0007216)3.06726073
65atrial cardiac muscle cell action potential (GO:0086014)3.05440735
66adult walking behavior (GO:0007628)3.05308071
67regulation of respiratory system process (GO:0044065)3.05283791
68central nervous system neuron axonogenesis (GO:0021955)3.03118501
69neuronal ion channel clustering (GO:0045161)2.96975770
70synapse assembly (GO:0007416)2.95731263
71synaptic vesicle docking involved in exocytosis (GO:0016081)2.94722504
72regulation of respiratory gaseous exchange (GO:0043576)2.92306454
73ganglion development (GO:0061548)2.91870359
74positive regulation of synaptic transmission, glutamatergic (GO:0051968)2.90977163
75membrane assembly (GO:0071709)2.90672441
76regulation of dendritic spine development (GO:0060998)2.88779251
77mechanosensory behavior (GO:0007638)2.87141021
78regulation of synapse assembly (GO:0051963)2.86921483
79amino acid import (GO:0043090)2.86281000
80regulation of synaptic transmission, GABAergic (GO:0032228)2.84408247
81neuromuscular synaptic transmission (GO:0007274)2.83919979
82positive regulation of dendritic spine morphogenesis (GO:0061003)2.82703800
83membrane depolarization (GO:0051899)2.81624512
84dendrite morphogenesis (GO:0048813)2.80379298
85axonal fasciculation (GO:0007413)2.80192171
86membrane hyperpolarization (GO:0060081)2.80093040
87response to auditory stimulus (GO:0010996)2.79115790
88learning (GO:0007612)2.78148920
89regulation of axon guidance (GO:1902667)2.77436201
90positive regulation of neurotransmitter transport (GO:0051590)2.76633094
91regulation of synaptic transmission, glutamatergic (GO:0051966)2.75539951
92neurotransmitter secretion (GO:0007269)2.74007323
93regulation of neurotransmitter secretion (GO:0046928)2.73323183
94positive regulation of inositol phosphate biosynthetic process (GO:0060732)2.72690204
95regulation of dendritic spine morphogenesis (GO:0061001)2.71494772
96cranial nerve structural organization (GO:0021604)2.71292072
97membrane depolarization during cardiac muscle cell action potential (GO:0086012)2.71219488
98urinary tract smooth muscle contraction (GO:0014848)2.69103662
99regulation of pigment cell differentiation (GO:0050932)2.68921934
100neuronal action potential (GO:0019228)2.68920155
101cranial nerve morphogenesis (GO:0021602)2.68715949
102cAMP catabolic process (GO:0006198)2.66136674
103regulation of axon extension involved in axon guidance (GO:0048841)2.65368894
104cyclic nucleotide catabolic process (GO:0009214)2.65143743
105regulation of synapse structural plasticity (GO:0051823)2.62546343
106negative regulation of neurotransmitter transport (GO:0051589)2.61844629
107regulation of vesicle fusion (GO:0031338)2.59119579
108positive regulation of synapse maturation (GO:0090129)2.58570845
109glycine transport (GO:0015816)2.58230372
110sympathetic nervous system development (GO:0048485)2.58228410
111facial nerve structural organization (GO:0021612)2.58067195
112regulation of synaptic plasticity (GO:0048167)2.58054389
113C4-dicarboxylate transport (GO:0015740)2.57674262
114regulation of inositol phosphate biosynthetic process (GO:0010919)2.57376209
115dendrite development (GO:0016358)2.56479370
116protein localization to cilium (GO:0061512)2.56147750
117dendritic spine organization (GO:0097061)2.55237022
118cerebellar granule cell differentiation (GO:0021707)2.55105847
119neurotransmitter transport (GO:0006836)2.54753489
120adult locomotory behavior (GO:0008344)2.53959987
121long-chain fatty acid biosynthetic process (GO:0042759)2.51894184
122retinal cone cell development (GO:0046549)2.51212086
123adult behavior (GO:0030534)2.50599752
124chemosensory behavior (GO:0007635)2.50558547
125appendage development (GO:0048736)2.49783860
126limb development (GO:0060173)2.49783860
127synapse organization (GO:0050808)2.48841206
128glycosphingolipid biosynthetic process (GO:0006688)2.47563516
129limb bud formation (GO:0060174)2.47444666
130homophilic cell adhesion via plasma membrane adhesion molecules (GO:0007156)2.45821141
131calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules (GO:0016339)2.45773706
132negative regulation of dendrite development (GO:2000171)2.41088008
133retina layer formation (GO:0010842)2.40061529
134regulation of atrial cardiac muscle cell membrane depolarization (GO:0060371)2.40055918
135cochlea development (GO:0090102)2.39933411
136regulation of gene silencing by RNA (GO:0060966)2.38902884
137regulation of posttranscriptional gene silencing (GO:0060147)2.38902884
138regulation of gene silencing by miRNA (GO:0060964)2.38902884

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1EZH2_22144423_ChIP-Seq_EOC_Human6.80492240
2GBX2_23144817_ChIP-Seq_PC3_Human3.92742699
3JARID2_20064375_ChIP-Seq_MESCs_Mouse3.33671564
4SUZ12_18692474_ChIP-Seq_MESCs_Mouse2.99604517
5EZH2_27304074_Chip-Seq_ESCs_Mouse2.82645382
6SUZ12_18555785_ChIP-Seq_MESCs_Mouse2.79238302
7RNF2_18974828_ChIP-Seq_MESCs_Mouse2.66227167
8EZH2_18974828_ChIP-Seq_MESCs_Mouse2.66227167
9JARID2_20075857_ChIP-Seq_MESCs_Mouse2.66149023
10SUZ12_16625203_ChIP-ChIP_MESCs_Mouse2.60412739
11SUZ12_18974828_ChIP-Seq_MESCs_Mouse2.56943283
12EED_16625203_ChIP-ChIP_MESCs_Mouse2.53700837
13SUZ12_18692474_ChIP-Seq_MEFs_Mouse2.48160459
14EZH2_27294783_Chip-Seq_ESCs_Mouse2.29695444
15SUZ12_20075857_ChIP-Seq_MESCs_Mouse2.27975729
16SUZ12_27294783_Chip-Seq_ESCs_Mouse2.27889673
17MTF2_20144788_ChIP-Seq_MESCs_Mouse2.25834632
18RNF2_27304074_Chip-Seq_ESCs_Mouse2.20017601
19REST_21632747_ChIP-Seq_MESCs_Mouse2.10530543
20ZFP57_27257070_Chip-Seq_ESCs_Mouse2.08770530
21CBX2_27304074_Chip-Seq_ESCs_Mouse2.01091971
22DROSHA_22980978_ChIP-Seq_HELA_Human1.97731735
23TAF15_26573619_Chip-Seq_HEK293_Human1.95731145
24GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.92618398
25IKZF1_21737484_ChIP-ChIP_HCT116_Human1.88302247
26BMI1_23680149_ChIP-Seq_NPCS_Mouse1.87214846
27PHC1_16625203_ChIP-ChIP_MESCs_Mouse1.83087903
28IGF1R_20145208_ChIP-Seq_DFB_Human1.79915023
29AR_21572438_ChIP-Seq_LNCaP_Human1.72171049
30RNF2_16625203_ChIP-ChIP_MESCs_Mouse1.71580247
31TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.70382427
32* CTBP2_25329375_ChIP-Seq_LNCAP_Human1.67298965
33CTBP1_25329375_ChIP-Seq_LNCAP_Human1.65597112
34SALL1_21062744_ChIP-ChIP_HESCs_Human1.64170039
35CDKN2AIP_20523734_ChIP-Seq_CORTICAL_Neurons1.63238703
36PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human1.62893844
37RNF2_27304074_Chip-Seq_NSC_Mouse1.57403846
38P300_19829295_ChIP-Seq_ESCs_Human1.52656037
39SMAD4_21799915_ChIP-Seq_A2780_Human1.49485428
40CDX2_19796622_ChIP-Seq_MESCs_Mouse1.48261474
41SMAD_19615063_ChIP-ChIP_OVARY_Human1.46868446
42REST_18959480_ChIP-ChIP_MESCs_Mouse1.46211752
43SMAD3_21741376_ChIP-Seq_EPCs_Human1.43718290
44RCOR2_21632747_ChIP-Seq_MESCs_Mouse1.43553962
45NR4A2_19515692_ChIP-ChIP_MN9D_Mouse1.43434676
46SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.43307946
47POU3F2_20337985_ChIP-ChIP_501MEL_Human1.42653125
48GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.38589350
49PCGF2_27294783_Chip-Seq_ESCs_Mouse1.34046247
50BCAT_22108803_ChIP-Seq_LS180_Human1.33549600
51EWS_26573619_Chip-Seq_HEK293_Human1.32640813
52RARB_27405468_Chip-Seq_BRAIN_Mouse1.32622917
53PIAS1_25552417_ChIP-Seq_VCAP_Human1.32244048
54FLI1_27457419_Chip-Seq_LIVER_Mouse1.28643066
55* SOX2_21211035_ChIP-Seq_LN229_Gbm1.28175913
56VDR_22108803_ChIP-Seq_LS180_Human1.27351416
57NANOG_18555785_Chip-Seq_ESCs_Mouse1.25970287
58TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse1.25712562
59TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.24588566
60HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.21661481
61SMAD2/3_21741376_ChIP-Seq_EPCs_Human1.21342709
62CEBPB_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.21026329
63CBP_20019798_ChIP-Seq_JUKART_Human1.20574474
64IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.20574474
65RING1B_27294783_Chip-Seq_ESCs_Mouse1.20527113
66EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.20065576
67ER_23166858_ChIP-Seq_MCF-7_Human1.19351559
68OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18568397
69SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse1.18447103
70TOP2B_26459242_ChIP-Seq_MCF-7_Human1.16836022
71CEBPB_26923725_Chip-Seq_MESODERM_Mouse1.16208275
72STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.16094219
73SMAD3_21741376_ChIP-Seq_ESCs_Human1.15657520
74KLF4_25985364_ChIP-Seq_ATHEROSCLEROSIS_LESION_Mouse1.15344633
75E2F1_18555785_Chip-Seq_ESCs_Mouse1.15171590
76AR_25329375_ChIP-Seq_VCAP_Human1.14588488
77P53_22387025_ChIP-Seq_ESCs_Mouse1.13373676
78* AR_19668381_ChIP-Seq_PC3_Human1.12783473
79SUZ12_27294783_Chip-Seq_NPCs_Mouse1.12745051
80ZNF274_21170338_ChIP-Seq_K562_Hela1.12334633
81RING1B_27294783_Chip-Seq_NPCs_Mouse1.11524306
82CMYC_18555785_Chip-Seq_ESCs_Mouse1.11378165
83PCGF2_27294783_Chip-Seq_NPCs_Mouse1.09188653
84TP53_16413492_ChIP-PET_HCT116_Human1.09035505
85LMO2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.08813328
86TCF4_22108803_ChIP-Seq_LS180_Human1.08556602
87RUNX2_22187159_ChIP-Seq_PCA_Human1.08147076
88VDR_23401126_ChIP-Seq_LCL-AND-THP1_Human1.07796479
89ARNT_22903824_ChIP-Seq_MCF-7_Human1.07205267
90BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.06796478
91TP53_18474530_ChIP-ChIP_U2OS_Human1.06793594
92CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.06788973
93SUZ12_18555785_Chip-Seq_ESCs_Mouse1.06691953
94* STAT3_23295773_ChIP-Seq_U87_Human1.05688606
95FUS_26573619_Chip-Seq_HEK293_Human1.05480160
96SMAD4_21741376_ChIP-Seq_HESCs_Human1.05163839
97SOX9_26525672_Chip-Seq_HEART_Mouse1.04882193
98EBF1_22473956_ChIP-Seq_LYMPHODE_Mouse1.04082179
99MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human1.03855389
100ZFP322A_24550733_ChIP-Seq_MESCs_Mouse1.02736477
101STAT3_18555785_Chip-Seq_ESCs_Mouse1.01886876
102P300_18555785_Chip-Seq_ESCs_Mouse1.01301277
103P53_22127205_ChIP-Seq_FIBROBLAST_Human1.00776858
104NFE2_27457419_Chip-Seq_LIVER_Mouse1.00213726
105* TCF4_23295773_ChIP-Seq_U87_Human1.00033468
106MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse0.99935430
107NMYC_18555785_Chip-Seq_ESCs_Mouse0.99661208
108RUNX1_27457419_Chip-Seq_LIVER_Mouse0.99508370
109PRDM14_20953172_ChIP-Seq_ESCs_Human0.99103470
110SOX2_18555785_Chip-Seq_ESCs_Mouse0.99001546
111TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human0.98031510
112TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.97134457
113POU5F1_26923725_Chip-Seq_MESODERM_Mouse0.97134457
114MEIS1_26923725_Chip-Seq_HEMOGENIC-ENDOTHELIUM_Mouse0.97130318
115KDM2B_26808549_Chip-Seq_REH_Human0.96069789
116TAL1_26923725_Chip-Seq_HEMANGIOBLAST_Mouse0.96043558
117* AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human0.94869093
118UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human0.94319638
119NR3C1_21868756_ChIP-Seq_MCF10A_Human0.93826668
120TAL1_26923725_Chip-Seq_HPCs_Mouse0.92494267
121EZH2_27294783_Chip-Seq_NPCs_Mouse0.92293627
122LMO2_26923725_Chip-Seq_MACROPHAGESS_Mouse0.89585851
123SMAD3_21741376_ChIP-Seq_HESCs_Human0.88557422

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003880_abnormal_central_pattern5.21548131
2MP0004859_abnormal_synaptic_plasticity4.58296360
3MP0003635_abnormal_synaptic_transmissio3.19849442
4MP0009745_abnormal_behavioral_response2.88975153
5MP0004270_analgesia2.88143845
6MP0005423_abnormal_somatic_nervous2.87497174
7MP0003136_yellow_coat_color2.87212015
8MP0001188_hyperpigmentation2.83156195
9MP0005409_darkened_coat_color2.79801682
10MP0001968_abnormal_touch/_nociception2.73076335
11MP0001486_abnormal_startle_reflex2.66355425
12MP0009046_muscle_twitch2.62817138
13MP0002064_seizures2.55946849
14MP0002272_abnormal_nervous_system2.40568955
15MP0002063_abnormal_learning/memory/cond2.38658053
16MP0002734_abnormal_mechanical_nocicepti2.28263462
17MP0002572_abnormal_emotion/affect_behav2.28191572
18MP0006292_abnormal_olfactory_placode2.25379542
19MP0009379_abnormal_foot_pigmentation2.24588823
20MP0002735_abnormal_chemical_nociception2.10572543
21MP0002736_abnormal_nociception_after1.94988914
22MP0002067_abnormal_sensory_capabilities1.94368104
23MP0000778_abnormal_nervous_system1.89285452
24MP0000569_abnormal_digit_pigmentation1.82725526
25MP0001970_abnormal_pain_threshold1.82296727
26MP0001501_abnormal_sleep_pattern1.82048475
27MP0006276_abnormal_autonomic_nervous1.78015293
28MP0002557_abnormal_social/conspecific_i1.75831963
29MP0002733_abnormal_thermal_nociception1.75235886
30MP0005646_abnormal_pituitary_gland1.73067220
31MP0004742_abnormal_vestibular_system1.72837017
32MP0005645_abnormal_hypothalamus_physiol1.70874651
33MP0002184_abnormal_innervation1.69701562
34MP0004142_abnormal_muscle_tone1.67412302
35MP0008569_lethality_at_weaning1.66809124
36MP0002102_abnormal_ear_morphology1.64219119
37MP0001440_abnormal_grooming_behavior1.60289664
38MP0002876_abnormal_thyroid_physiology1.57897312
39MP0003890_abnormal_embryonic-extraembry1.50889566
40MP0005174_abnormal_tail_pigmentation1.50612257
41MP0003879_abnormal_hair_cell1.50280826
42MP0005171_absent_coat_pigmentation1.49974968
43MP0001986_abnormal_taste_sensitivity1.48607483
44MP0001905_abnormal_dopamine_level1.44560729
45MP0000015_abnormal_ear_pigmentation1.43714016
46MP0000920_abnormal_myelination1.42827642
47MP0001502_abnormal_circadian_rhythm1.38761976
48MP0002638_abnormal_pupillary_reflex1.36963761
49MP0008877_abnormal_DNA_methylation1.35866017
50MP0003119_abnormal_digestive_system1.34548066
51MP0001984_abnormal_olfaction1.33564183
52MP0002882_abnormal_neuron_morphology1.32367484
53MP0000631_abnormal_neuroendocrine_gland1.30034170
54MP0000955_abnormal_spinal_cord1.27299963
55MP0004381_abnormal_hair_follicle1.25238156
56MP0004885_abnormal_endolymph1.24441621
57MP0004133_heterotaxia1.23055348
58MP0005551_abnormal_eye_electrophysiolog1.21754589
59MP0001963_abnormal_hearing_physiology1.19950169
60MP0003121_genomic_imprinting1.18576481
61MP0003122_maternal_imprinting1.18317766
62MP0005386_behavior/neurological_phenoty1.17764800
63MP0004924_abnormal_behavior1.17764800
64MP0002066_abnormal_motor_capabilities/c1.17139995
65MP0003861_abnormal_nervous_system1.13366536
66MP0000026_abnormal_inner_ear1.12378709
67MP0004811_abnormal_neuron_physiology1.12032047
68MP0002822_catalepsy1.11299965
69MP0003283_abnormal_digestive_organ1.10117506
70MP0002938_white_spotting1.09852091
71MP0003938_abnormal_ear_development1.08546319
72MP0008872_abnormal_physiological_respon1.05655213
73MP0005503_abnormal_tendon_morphology1.05146135
74MP0001485_abnormal_pinna_reflex1.04893205
75MP0002752_abnormal_somatic_nervous1.02525751
76MP0003937_abnormal_limbs/digits/tail_de1.00947378
77MP0002229_neurodegeneration0.99842721
78MP0005257_abnormal_intraocular_pressure0.98222763
79MP0001529_abnormal_vocalization0.97994192
80MP0003633_abnormal_nervous_system0.96912702
81MP0004145_abnormal_muscle_electrophysio0.93612500
82MP0001299_abnormal_eye_distance/0.92601140
83MP0008260_abnormal_autophagy0.92088728
84MP0000681_abnormal_thyroid_gland0.91840971
85MP0003787_abnormal_imprinting0.85282652
86MP0003632_abnormal_nervous_system0.84921488
87MP0000566_synostosis0.84591930
88MP0002152_abnormal_brain_morphology0.84226263
89MP0003634_abnormal_glial_cell0.84116211
90MP0003878_abnormal_ear_physiology0.83892809
91MP0005377_hearing/vestibular/ear_phenot0.83892809
92MP0001664_abnormal_digestion0.83843196
93MP0010386_abnormal_urinary_bladder0.82751174
94MP0002751_abnormal_autonomic_nervous0.81574262
95MP0000372_irregular_coat_pigmentation0.81135950
96MP0005195_abnormal_posterior_eye0.80874210
97MP0009780_abnormal_chondrocyte_physiolo0.80407355
98MP0003724_increased_susceptibility_to0.80190506
99MP0003690_abnormal_glial_cell0.79699933
100MP0005379_endocrine/exocrine_gland_phen0.78723313
101MP0009250_abnormal_appendicular_skeleto0.78720000
102MP0003631_nervous_system_phenotype0.77020781
103MP0002234_abnormal_pharynx_morphology0.75927091
104MP0002653_abnormal_ependyma_morphology0.74868618
105MP0002082_postnatal_lethality0.73476111
106MP0010770_preweaning_lethality0.73476111
107MP0003755_abnormal_palate_morphology0.73428164
108MP0002177_abnormal_outer_ear0.73234349
109MP0004858_abnormal_nervous_system0.73044965
110MP0002095_abnormal_skin_pigmentation0.72352187
111MP0005253_abnormal_eye_physiology0.72270911
112MP0004510_myositis0.70069909
113MP0000049_abnormal_middle_ear0.70057937
114MP0001348_abnormal_lacrimal_gland0.69441250
115MP0010769_abnormal_survival0.68826870
116MP0002116_abnormal_craniofacial_bone0.68665176
117MP0001293_anophthalmia0.68397460
118MP0006072_abnormal_retinal_apoptosis0.67446101
119MP0003303_peritoneal_inflammation0.65831525
120MP0008874_decreased_physiological_sensi0.65302993
121MP0001177_atelectasis0.63937336
122MP0002069_abnormal_eating/drinking_beha0.63009132
123MP0003329_amyloid_beta_deposits0.59201656
124MP0005394_taste/olfaction_phenotype0.57836229
125MP0005499_abnormal_olfactory_system0.57836229
126MP0002909_abnormal_adrenal_gland0.57016665
127MP0002249_abnormal_larynx_morphology0.56031735
128MP0002163_abnormal_gland_morphology0.55456242

Predicted human phenotypes

RankGene SetZ-score
1Focal motor seizures (HP:0011153)6.85864521
2Myokymia (HP:0002411)4.77795795
3Febrile seizures (HP:0002373)4.19308601
4Focal seizures (HP:0007359)4.07950836
5Epileptic encephalopathy (HP:0200134)3.83610134
6Gaze-evoked nystagmus (HP:0000640)3.67017278
7Progressive cerebellar ataxia (HP:0002073)3.65129976
8Broad-based gait (HP:0002136)3.34881049
9Action tremor (HP:0002345)3.12989045
10Atonic seizures (HP:0010819)3.07930043
11Protruding tongue (HP:0010808)3.02666567
12Nonprogressive disorder (HP:0003680)2.92553960
13Absent/shortened dynein arms (HP:0200106)2.89313181
14Dynein arm defect of respiratory motile cilia (HP:0012255)2.89313181
15Abnormality of the labia minora (HP:0012880)2.89148452
16Visual hallucinations (HP:0002367)2.86419540
17Type I transferrin isoform profile (HP:0003642)2.72865550
18Thyroid-stimulating hormone excess (HP:0002925)2.72636701
19Generalized tonic-clonic seizures (HP:0002069)2.65859746
20Obstructive sleep apnea (HP:0002870)2.65455288
21Progressive inability to walk (HP:0002505)2.64892131
22Hypothermia (HP:0002045)2.61667477
23Dialeptic seizures (HP:0011146)2.60191695
24Epileptiform EEG discharges (HP:0011182)2.56542062
25Hepatoblastoma (HP:0002884)2.54157603
26Chronic hepatic failure (HP:0100626)2.52765124
27EEG with generalized epileptiform discharges (HP:0011198)2.50632428
28Absence seizures (HP:0002121)2.50442152
29Decreased central vision (HP:0007663)2.49405952
30Agitation (HP:0000713)2.48937428
31Hemiparesis (HP:0001269)2.47639625
32Hypsarrhythmia (HP:0002521)2.46924077
33Peripheral hypomyelination (HP:0007182)2.44102734
34Split foot (HP:0001839)2.42692400
35Aplasia/Hypoplasia of the pubic bone (HP:0009104)2.42431635
36Intestinal atresia (HP:0011100)2.39952640
37Absent rod-and cone-mediated responses on ERG (HP:0007688)2.39079501
38Abnormal eating behavior (HP:0100738)2.37846589
39Nephronophthisis (HP:0000090)2.37369457
40Abnormality of midbrain morphology (HP:0002418)2.36439493
41Molar tooth sign on MRI (HP:0002419)2.36439493
42Dysmetria (HP:0001310)2.36300350
43Reduced antithrombin III activity (HP:0001976)2.36204804
44Limb dystonia (HP:0002451)2.35889248
45Abnormal ciliary motility (HP:0012262)2.34947959
46Optic nerve hypoplasia (HP:0000609)2.34012292
47Aplasia/Hypoplasia of the sternum (HP:0006714)2.33734871
48Absent septum pellucidum (HP:0001331)2.31013349
49Mutism (HP:0002300)2.30641633
50Anxiety (HP:0000739)2.30378612
51Absent speech (HP:0001344)2.30001812
52Cutaneous finger syndactyly (HP:0010554)2.29705673
53Abnormality of magnesium homeostasis (HP:0004921)2.28636547
54Hyperventilation (HP:0002883)2.28031785
55Cortical visual impairment (HP:0100704)2.27652203
56Vitreoretinal degeneration (HP:0000655)2.27449880
57Septo-optic dysplasia (HP:0100842)2.24929934
58Dysdiadochokinesis (HP:0002075)2.23292276
59Supranuclear gaze palsy (HP:0000605)2.20434729
60Pancreatic cysts (HP:0001737)2.20178886
61Bowel diverticulosis (HP:0005222)2.19861500
62Abnormality of the pubic bones (HP:0003172)2.19274939
63Scanning speech (HP:0002168)2.18315115
64Abnormality of secondary sexual hair (HP:0009888)2.18255033
65Abnormality of the axillary hair (HP:0100134)2.18255033
66Astrocytoma (HP:0009592)2.17327285
67Abnormality of the astrocytes (HP:0100707)2.17327285
68Congenital stationary night blindness (HP:0007642)2.16911375
69Retinal dysplasia (HP:0007973)2.16885027
70Morphological abnormality of the middle ear (HP:0008609)2.14586403
71Keratoconus (HP:0000563)2.14554979
72Increased corneal curvature (HP:0100692)2.14554979
73Parakeratosis (HP:0001036)2.13856282
74Pancreatic fibrosis (HP:0100732)2.12924532
75Lissencephaly (HP:0001339)2.10814218
76Inability to walk (HP:0002540)2.10519836
77Abolished electroretinogram (ERG) (HP:0000550)2.07731753
78Aqueductal stenosis (HP:0002410)2.07118029
79Cystic liver disease (HP:0006706)2.05203715
80Abnormality of calcium-phosphate metabolism (HP:0100530)2.04189676
81Abnormal respiratory epithelium morphology (HP:0012253)2.01640488
82Abnormal respiratory motile cilium morphology (HP:0005938)2.01640488
83Renovascular hypertension (HP:0100817)2.01364635
84Abnormality of the ischium (HP:0003174)2.00937167
85Hypomagnesemia (HP:0002917)2.00617540
86Depression (HP:0000716)2.00331862
87Hypoplastic ischia (HP:0003175)1.99937265
88Type II lissencephaly (HP:0007260)1.99709529
89Abnormality of the septum pellucidum (HP:0007375)1.97975828
90Esotropia (HP:0000565)1.96716756
91Stereotypic behavior (HP:0000733)1.96652179
92Blue irides (HP:0000635)1.96190000
93Ankle clonus (HP:0011448)1.94321348
94Fetal akinesia sequence (HP:0001989)1.94026553
95Attenuation of retinal blood vessels (HP:0007843)1.93892042
96Sleep apnea (HP:0010535)1.93738605
97Volvulus (HP:0002580)1.93640946
98Urethral obstruction (HP:0000796)1.93104078
99Renal hypoplasia (HP:0000089)1.92830167
100Genetic anticipation (HP:0003743)1.92764431
101Abnormal rod and cone electroretinograms (HP:0008323)1.92553324
102Aplasia involving bones of the upper limbs (HP:0009823)1.91916299
103Aplasia of the phalanges of the hand (HP:0009802)1.91916299
104Aplasia involving bones of the extremities (HP:0009825)1.91916299
105Congenital sensorineural hearing impairment (HP:0008527)1.91126378
106Abnormal respiratory motile cilium physiology (HP:0012261)1.91091458
107Colon cancer (HP:0003003)1.90787953
108Drooling (HP:0002307)1.89655495
109Excessive salivation (HP:0003781)1.89655495
110Abnormality of the diencephalon (HP:0010662)1.88894179
111Glioma (HP:0009733)1.88598629
112Urinary bladder sphincter dysfunction (HP:0002839)1.87654435
113Amblyopia (HP:0000646)1.87364434
114Hypoventilation (HP:0002791)1.87346233
115Alacrima (HP:0000522)1.87204592
116Gait imbalance (HP:0002141)1.87084455
117Cutaneous syndactyly (HP:0012725)1.87047584
118Abnormality of the renal medulla (HP:0100957)1.86966538
119Tented upper lip vermilion (HP:0010804)1.84724492
120Iris hypopigmentation (HP:0007730)1.84602439
121Pachygyria (HP:0001302)1.84567296
122Abnormal hair whorl (HP:0010721)1.84098717
123Pendular nystagmus (HP:0012043)1.83516599
124True hermaphroditism (HP:0010459)1.83479012
125Hemiplegia (HP:0002301)1.83306689
126Genital tract atresia (HP:0001827)1.82729473
127Bradycardia (HP:0001662)1.82391856
128Renal Fanconi syndrome (HP:0001994)1.82109386
129Severe visual impairment (HP:0001141)1.81940887
130Cupped ear (HP:0000378)1.81555617
131Stomatitis (HP:0010280)1.81516043
132Vaginal atresia (HP:0000148)1.81510243
133Diplopia (HP:0000651)1.81172323
134Abnormality of binocular vision (HP:0011514)1.81172323
135Broad metatarsal (HP:0001783)1.78915176
136Medial flaring of the eyebrow (HP:0010747)1.78242002
137Sclerocornea (HP:0000647)1.78235771
138Polyphagia (HP:0002591)1.77728210
139Respiratory insufficiency due to defective ciliary clearance (HP:0200073)1.76536672
140Patellar aplasia (HP:0006443)1.76251121
141Aplasia/Hypoplasia of the optic nerve (HP:0008058)1.75733590
142Poor eye contact (HP:0000817)1.75663414
143Ocular albinism (HP:0001107)1.75437462
144Shawl scrotum (HP:0000049)1.75398539
1453-Methylglutaconic aciduria (HP:0003535)1.75318714
146Sensory axonal neuropathy (HP:0003390)1.75248784
147Generalized hypopigmentation of hair (HP:0011358)1.73823723
148Impaired smooth pursuit (HP:0007772)1.73446466
149Flat cornea (HP:0007720)1.72772642
150Patchy hypopigmentation of hair (HP:0011365)1.72618746
151Abnormal protein glycosylation (HP:0012346)1.72232073
152Abnormal glycosylation (HP:0012345)1.72232073
153Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.72232073
154Abnormal protein N-linked glycosylation (HP:0012347)1.72232073
155White forelock (HP:0002211)1.71921949
156Gastroesophageal reflux (HP:0002020)1.70899745
157Muscle abnormality related to mitochondrial dysfunction (HP:0003800)1.70774204
158Oligodactyly (hands) (HP:0001180)1.69588313
159Anophthalmia (HP:0000528)1.69316814
160Conical tooth (HP:0000698)1.68849909
161Short foot (HP:0001773)1.62915694
162Narrow nasal bridge (HP:0000446)1.62669167
163Preaxial foot polydactyly (HP:0001841)1.61360724
164Megalencephaly (HP:0001355)1.59873821
165Bilateral microphthalmos (HP:0007633)1.59802735
166Narrow forehead (HP:0000341)1.59742865
167Midline defect of the nose (HP:0004122)1.59594440
168Highly arched eyebrow (HP:0002553)1.59021496

Predicted kinase interactions (KEA)

RankGene SetZ-score
1TNIK5.31948758
2CASK4.79037432
3FRK4.39420884
4NTRK33.63837081
5EPHA42.82274127
6MAP2K72.72078160
7MARK12.62910440
8MUSK2.60396672
9FES2.19331197
10PRPF4B2.11827306
11MKNK22.06603922
12MAPK132.06174093
13PNCK2.02741378
14CDK191.91094739
15RIPK41.68523481
16NTRK21.63456068
17MAP3K121.61343265
18CAMK1G1.57630597
19DAPK21.51890775
20CAMKK21.49060508
21MAP3K41.46746107
22ACVR1B1.40477014
23OXSR11.39870774
24MINK11.39703955
25PAK31.29860408
26MAP4K21.26160130
27UHMK11.23867924
28EPHA31.21466696
29CAMK1D1.21101742
30CAMK11.19922234
31STK391.18027648
32EIF2AK31.17831639
33BMPR21.16386348
34PAK61.15186325
35TYRO31.13127932
36CDK51.08941184
37MAP3K91.07547229
38NEK61.06993534
39PRKCH1.04447822
40CAMKK11.03539940
41CAMK2B1.01703154
42FGFR21.00691519
43GRK50.98974488
44INSRR0.98800527
45BLK0.97800871
46CAMK2A0.97667104
47PKN10.96170469
48MKNK10.96041192
49NUAK10.95327053
50ADRBK20.92278410
51IRAK40.91854402
52PRKD20.91785849
53CLK10.91361547
54NTRK10.89897375
55IRAK20.89469289
56SIK20.88879423
57PHKG10.86946212
58PHKG20.86946212
59EIF2AK20.83557548
60MAP2K40.82807377
61STK160.82644390
62PINK10.82136942
63GRK70.81327722
64CSNK1G20.80321826
65YES10.80262852
66PRKCG0.78846418
67CDK30.77872673
68IRAK10.76723152
69STK380.73711283
70ZAK0.73437535
71DYRK1A0.70961514
72FGR0.70857308
73EPHB20.69553564
74TNK20.68576413
75NLK0.67963019
76TAF10.67856914
77MAPKAPK50.67779400
78IRAK30.66616808
79CAMK40.66561470
80CSNK1G30.64746153
81TRIM280.63773961
82ERBB20.63321736
83PRKCE0.63095404
84STK110.62854619
85CAMK2D0.62268049
86STK38L0.62260258
87FER0.62178266
88DYRK20.60686536
89DAPK10.59899194
90PRKCZ0.58595792
91SGK4940.57515740
92SGK2230.57515740
93CSNK1G10.57256527
94TLK10.54959552
95ERBB40.54467086
96GRK10.54346457
97MARK20.52160156
98CSNK1A1L0.49737049
99WNK40.48549396
100HIPK20.47683560
101PTK2B0.47622034
102CSNK1D0.47478678
103PLK20.47199352
104NME10.46026397
105FYN0.45394371
106TXK0.45038561
107CAMK2G0.44170442
108GSK3B0.44054601
109PRKG10.43948141
110BMPR1B0.43747887
111MAP3K10.43091687
112PRKAA10.42727417
113BCR0.42649742
114CDK140.42610618
115CSNK1A10.42346547
116SGK10.41626818
117PRKD30.41354709
118RPS6KA30.41003097
119CDK11A0.40310900
120ROCK10.40054502
121CDC70.39639456
122MAP3K130.39452009
123CDK150.38945479
124SGK20.38380375
125CDK180.38104258
126PRKDC0.37309859
127TGFBR10.36958066
128PRKCB0.35770101
129PRKACA0.35282415
130LATS10.35216667
131CSNK1E0.34981606
132ADRBK10.34213536
133DDR20.33606567
134WNK30.32709535
135PRKACB0.32436648
136WNK10.32295544
137MAPK80.32281898
138MAPK120.31461968
139BRD40.30436124
140MAPK100.28313223
141ERBB30.28053948

Predicted pathways (KEGG)

RankGene SetZ-score
1Nicotine addiction_Homo sapiens_hsa050333.78806221
2Glutamatergic synapse_Homo sapiens_hsa047242.70881887
3Retrograde endocannabinoid signaling_Homo sapiens_hsa047232.54664480
4Morphine addiction_Homo sapiens_hsa050322.54122460
5GABAergic synapse_Homo sapiens_hsa047272.41069971
6Circadian entrainment_Homo sapiens_hsa047132.40003827
7Synaptic vesicle cycle_Homo sapiens_hsa047212.36486564
8Olfactory transduction_Homo sapiens_hsa047402.28700264
9Serotonergic synapse_Homo sapiens_hsa047261.98215330
10Amphetamine addiction_Homo sapiens_hsa050311.94862381
11Taste transduction_Homo sapiens_hsa047421.94258797
12Neuroactive ligand-receptor interaction_Homo sapiens_hsa040801.89068333
13Salivary secretion_Homo sapiens_hsa049701.87999462
14Long-term potentiation_Homo sapiens_hsa047201.86427557
15Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005331.84446959
16Phototransduction_Homo sapiens_hsa047441.83401624
17Cholinergic synapse_Homo sapiens_hsa047251.78642971
18Long-term depression_Homo sapiens_hsa047301.75855267
19Insulin secretion_Homo sapiens_hsa049111.70283881
20Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.68191022
21Butanoate metabolism_Homo sapiens_hsa006501.65694170
22Dopaminergic synapse_Homo sapiens_hsa047281.65434930
23Calcium signaling pathway_Homo sapiens_hsa040201.58604431
24Cocaine addiction_Homo sapiens_hsa050301.56978681
25Aldosterone synthesis and secretion_Homo sapiens_hsa049251.56002002
26Axon guidance_Homo sapiens_hsa043601.49198975
27Lysine degradation_Homo sapiens_hsa003101.37963752
28Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.35953385
29Gastric acid secretion_Homo sapiens_hsa049711.33035181
30Oxytocin signaling pathway_Homo sapiens_hsa049211.27789860
31Renin secretion_Homo sapiens_hsa049241.24906007
32Cell adhesion molecules (CAMs)_Homo sapiens_hsa045141.22455823
33cAMP signaling pathway_Homo sapiens_hsa040241.22141316
34Collecting duct acid secretion_Homo sapiens_hsa049661.20481450
35Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049611.18325950
36Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047501.11526042
37GnRH signaling pathway_Homo sapiens_hsa049121.10433491
38SNARE interactions in vesicular transport_Homo sapiens_hsa041301.08825100
39Basal cell carcinoma_Homo sapiens_hsa052171.07746358
40Hedgehog signaling pathway_Homo sapiens_hsa043401.07391852
41Ether lipid metabolism_Homo sapiens_hsa005651.03888600
42Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006031.03676167
43Sphingolipid metabolism_Homo sapiens_hsa006001.02575997
44Pancreatic secretion_Homo sapiens_hsa049721.00334945
45Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042610.99795287
46Gap junction_Homo sapiens_hsa045400.98717609
47Hippo signaling pathway_Homo sapiens_hsa043900.97983101
48Other types of O-glycan biosynthesis_Homo sapiens_hsa005140.96541616
49Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.95746528
50Melanogenesis_Homo sapiens_hsa049160.93396930
51Type I diabetes mellitus_Homo sapiens_hsa049400.93277286
52Oxidative phosphorylation_Homo sapiens_hsa001900.91400626
53Cardiac muscle contraction_Homo sapiens_hsa042600.91199049
54alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.90674783
55Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.90176259
56Rheumatoid arthritis_Homo sapiens_hsa053230.90080042
57Selenocompound metabolism_Homo sapiens_hsa004500.86631268
58Phospholipase D signaling pathway_Homo sapiens_hsa040720.84196234
59Vascular smooth muscle contraction_Homo sapiens_hsa042700.83653920
60ErbB signaling pathway_Homo sapiens_hsa040120.82539975
61Linoleic acid metabolism_Homo sapiens_hsa005910.82403931
62Alzheimers disease_Homo sapiens_hsa050100.81423724
63Vibrio cholerae infection_Homo sapiens_hsa051100.79579544
64Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054120.78245393
65Graft-versus-host disease_Homo sapiens_hsa053320.77382654
66Ras signaling pathway_Homo sapiens_hsa040140.77083290
67Phosphatidylinositol signaling system_Homo sapiens_hsa040700.76775338
68Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75936654
69Protein export_Homo sapiens_hsa030600.75615896
70African trypanosomiasis_Homo sapiens_hsa051430.75066861
71Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.75010845
72Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.74083280
73Nitrogen metabolism_Homo sapiens_hsa009100.73866840
74Type II diabetes mellitus_Homo sapiens_hsa049300.73682400
75Basal transcription factors_Homo sapiens_hsa030220.72845813
76Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.71888082
77Ovarian steroidogenesis_Homo sapiens_hsa049130.71480399
78ABC transporters_Homo sapiens_hsa020100.71130352
79Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.70920807
80Maturity onset diabetes of the young_Homo sapiens_hsa049500.70816445
81Vasopressin-regulated water reabsorption_Homo sapiens_hsa049620.70605721
82MAPK signaling pathway_Homo sapiens_hsa040100.68779704
83Wnt signaling pathway_Homo sapiens_hsa043100.66706369
84cGMP-PKG signaling pathway_Homo sapiens_hsa040220.66668806
85Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa006040.66643482
86Oocyte meiosis_Homo sapiens_hsa041140.66206276
87Autoimmune thyroid disease_Homo sapiens_hsa053200.65174491
88Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa050140.62906443
89Fanconi anemia pathway_Homo sapiens_hsa034600.62435240
90Asthma_Homo sapiens_hsa053100.62191544
91Tryptophan metabolism_Homo sapiens_hsa003800.61765424
92Choline metabolism in cancer_Homo sapiens_hsa052310.61137580
93Chemokine signaling pathway_Homo sapiens_hsa040620.60549637
94Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.60401874
95Dorso-ventral axis formation_Homo sapiens_hsa043200.59020266
96Allograft rejection_Homo sapiens_hsa053300.58491188
97Alcoholism_Homo sapiens_hsa050340.57389037
98Sphingolipid signaling pathway_Homo sapiens_hsa040710.55300157
99Protein digestion and absorption_Homo sapiens_hsa049740.52969144
100Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.52933794
101Circadian rhythm_Homo sapiens_hsa047100.52837953
102Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.51950751
103Estrogen signaling pathway_Homo sapiens_hsa049150.49142367
104Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.48068913
105Primary bile acid biosynthesis_Homo sapiens_hsa001200.47256092
106Bile secretion_Homo sapiens_hsa049760.46297274
107Arachidonic acid metabolism_Homo sapiens_hsa005900.46278338
108Other glycan degradation_Homo sapiens_hsa005110.45128578
109Melanoma_Homo sapiens_hsa052180.45123062
110RNA polymerase_Homo sapiens_hsa030200.44944278
111Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.44817954
112Thyroid hormone synthesis_Homo sapiens_hsa049180.44663182
113Parkinsons disease_Homo sapiens_hsa050120.43963026
114TGF-beta signaling pathway_Homo sapiens_hsa043500.43655948
115Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.43193383
116Rap1 signaling pathway_Homo sapiens_hsa040150.42493702
117Tight junction_Homo sapiens_hsa045300.42295115
118Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.41240437
119Glioma_Homo sapiens_hsa052140.40638496
120ECM-receptor interaction_Homo sapiens_hsa045120.39818589
121Glycerolipid metabolism_Homo sapiens_hsa005610.39216940
122Phagosome_Homo sapiens_hsa041450.37583431
123Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.36756902
124Salmonella infection_Homo sapiens_hsa051320.35908191
125Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.35107694
126N-Glycan biosynthesis_Homo sapiens_hsa005100.34865870
127Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.34765590
128Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.34312838
129Huntingtons disease_Homo sapiens_hsa050160.34280960
130beta-Alanine metabolism_Homo sapiens_hsa004100.34179576
131Malaria_Homo sapiens_hsa051440.33455041
132Dilated cardiomyopathy_Homo sapiens_hsa054140.31405770
133NOD-like receptor signaling pathway_Homo sapiens_hsa046210.30953235
134Tuberculosis_Homo sapiens_hsa051520.29123870

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