

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | detection of molecule of bacterial origin (GO:0032490) | 6.87599374 |
| 2 | positive regulation of nitric-oxide synthase biosynthetic process (GO:0051770) | 5.94218746 |
| 3 | positive regulation of gamma-delta T cell activation (GO:0046645) | 5.93083805 |
| 4 | positive regulation by symbiont of host defense response (GO:0052509) | 5.51966358 |
| 5 | modulation by symbiont of host defense response (GO:0052031) | 5.51966358 |
| 6 | modulation by organism of immune response of other organism involved in symbiotic interaction (GO:00 | 5.51966358 |
| 7 | modulation by organism of defense response of other organism involved in symbiotic interaction (GO:0 | 5.51966358 |
| 8 | positive regulation by organism of defense response of other organism involved in symbiotic interact | 5.51966358 |
| 9 | modulation by symbiont of host immune response (GO:0052553) | 5.51966358 |
| 10 | microglial cell activation (GO:0001774) | 5.45814771 |
| 11 | regulation of B cell receptor signaling pathway (GO:0050855) | 5.11186724 |
| 12 | neutrophil mediated immunity (GO:0002446) | 5.01482220 |
| 13 | positive regulation of antigen receptor-mediated signaling pathway (GO:0050857) | 4.71674022 |
| 14 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 4.63561424 |
| 15 | positive regulation of tumor necrosis factor biosynthetic process (GO:0042535) | 4.62385812 |
| 16 | myeloid leukocyte mediated immunity (GO:0002444) | 4.42804105 |
| 17 | negative regulation of leukocyte mediated cytotoxicity (GO:0001911) | 4.42632915 |
| 18 | negative regulation of cell killing (GO:0031342) | 4.42632915 |
| 19 | cytidine deamination (GO:0009972) | 4.37692260 |
| 20 | cytidine metabolic process (GO:0046087) | 4.37692260 |
| 21 | cytidine catabolic process (GO:0006216) | 4.37692260 |
| 22 | detection of external biotic stimulus (GO:0098581) | 4.37035556 |
| 23 | cellular extravasation (GO:0045123) | 4.35859589 |
| 24 | regulation of nitric-oxide synthase biosynthetic process (GO:0051769) | 4.26414031 |
| 25 | macrophage activation (GO:0042116) | 4.26159029 |
| 26 | regulation of gamma-delta T cell differentiation (GO:0045586) | 4.24115129 |
| 27 | regulation of humoral immune response mediated by circulating immunoglobulin (GO:0002923) | 4.17365165 |
| 28 | regulation of gamma-delta T cell activation (GO:0046643) | 4.15141454 |
| 29 | macrophage activation involved in immune response (GO:0002281) | 4.11954384 |
| 30 | response to immune response of other organism involved in symbiotic interaction (GO:0052564) | 4.08471944 |
| 31 | response to host immune response (GO:0052572) | 4.08471944 |
| 32 | pyrimidine ribonucleoside catabolic process (GO:0046133) | 4.02499973 |
| 33 | Arp2/3 complex-mediated actin nucleation (GO:0034314) | 4.01369659 |
| 34 | respiratory burst (GO:0045730) | 3.99435209 |
| 35 | positive regulation of interleukin-8 biosynthetic process (GO:0045416) | 3.98653419 |
| 36 | regulation of interferon-beta biosynthetic process (GO:0045357) | 3.94877848 |
| 37 | negative T cell selection (GO:0043383) | 3.78060420 |
| 38 | negative regulation of B cell proliferation (GO:0030889) | 3.77981673 |
| 39 | detection of biotic stimulus (GO:0009595) | 3.76420984 |
| 40 | leukocyte migration involved in inflammatory response (GO:0002523) | 3.67481888 |
| 41 | activated T cell proliferation (GO:0050798) | 3.66616712 |
| 42 | neutrophil activation (GO:0042119) | 3.63385235 |
| 43 | regulation of regulatory T cell differentiation (GO:0045589) | 3.60398171 |
| 44 | leukocyte aggregation (GO:0070486) | 3.58666924 |
| 45 | regulation of interleukin-6 biosynthetic process (GO:0045408) | 3.57010077 |
| 46 | response to host (GO:0075136) | 3.56884463 |
| 47 | response to host defenses (GO:0052200) | 3.56884463 |
| 48 | response to defenses of other organism involved in symbiotic interaction (GO:0052173) | 3.56884463 |
| 49 | interferon-gamma production (GO:0032609) | 3.50720924 |
| 50 | negative regulation of interleukin-12 production (GO:0032695) | 3.41503773 |
| 51 | granulocyte activation (GO:0036230) | 3.39155643 |
| 52 | actin nucleation (GO:0045010) | 3.38236225 |
| 53 | detection of other organism (GO:0098543) | 3.33917284 |
| 54 | negative regulation of lymphocyte mediated immunity (GO:0002707) | 3.33030230 |
| 55 | negative regulation of platelet-derived growth factor receptor signaling pathway (GO:0010642) | 3.32465256 |
| 56 | positive regulation of B cell differentiation (GO:0045579) | 3.29504262 |
| 57 | negative regulation of interleukin-17 production (GO:0032700) | 3.27977917 |
| 58 | neutrophil activation involved in immune response (GO:0002283) | 3.26396639 |
| 59 | negative thymic T cell selection (GO:0045060) | 3.25764995 |
| 60 | DNA deamination (GO:0045006) | 3.24414966 |
| 61 | positive T cell selection (GO:0043368) | 3.22260411 |
| 62 | regulation of interleukin-12 biosynthetic process (GO:0045075) | 3.21795415 |
| 63 | cellular response to interleukin-15 (GO:0071350) | 3.20895509 |
| 64 | neural tube formation (GO:0001841) | 3.17325995 |
| 65 | positive regulation of toll-like receptor signaling pathway (GO:0034123) | 3.14930640 |
| 66 | leukotriene biosynthetic process (GO:0019370) | 3.14417102 |
| 67 | response to interleukin-15 (GO:0070672) | 3.13511328 |
| 68 | myeloid cell activation involved in immune response (GO:0002275) | 3.13240855 |
| 69 | negative regulation of amyloid precursor protein catabolic process (GO:1902992) | 3.12294868 |
| 70 | negative regulation of B cell mediated immunity (GO:0002713) | 3.11496996 |
| 71 | negative regulation of immunoglobulin mediated immune response (GO:0002890) | 3.11496996 |
| 72 | regulation of tumor necrosis factor biosynthetic process (GO:0042534) | 3.10793054 |
| 73 | pantothenate metabolic process (GO:0015939) | 3.10393008 |
| 74 | positive regulation of interleukin-1 beta secretion (GO:0050718) | 3.09955332 |
| 75 | dendritic cell migration (GO:0036336) | 3.07760193 |
| 76 | production of molecular mediator involved in inflammatory response (GO:0002532) | 3.06165160 |
| 77 | B cell receptor signaling pathway (GO:0050853) | 3.04803615 |
| 78 | sequestering of actin monomers (GO:0042989) | 3.03844110 |
| 79 | negative regulation of T cell mediated immunity (GO:0002710) | 3.03700197 |
| 80 | regulation of B cell differentiation (GO:0045577) | 3.03273305 |
| 81 | positive regulation of interleukin-1 production (GO:0032732) | 3.00751486 |
| 82 | regulation of protein kinase A signaling (GO:0010738) | 2.91554127 |
| 83 | negative regulation of CD4-positive, alpha-beta T cell activation (GO:2000515) | 2.90204568 |
| 84 | regulation of alpha-beta T cell proliferation (GO:0046640) | 2.89688618 |
| 85 | hepatocyte apoptotic process (GO:0097284) | 2.89023742 |
| 86 | positive regulation of interleukin-1 secretion (GO:0050716) | 2.88962630 |
| 87 | I-kappaB phosphorylation (GO:0007252) | 2.88332154 |
| 88 | histone mRNA catabolic process (GO:0071044) | 2.88118760 |
| 89 | T cell mediated immunity (GO:0002456) | 2.86766772 |
| 90 | neutrophil chemotaxis (GO:0030593) | 2.82728927 |
| 91 | cytokine secretion (GO:0050663) | 2.82340453 |
| 92 | positive regulation of T cell mediated cytotoxicity (GO:0001916) | 2.81567123 |
| 93 | cellular defense response (GO:0006968) | 2.80800619 |
| 94 | negative regulation of adaptive immune response based on somatic recombination of immune receptors b | 2.77848182 |
| 95 | positive regulation of leukocyte mediated cytotoxicity (GO:0001912) | 2.77241165 |
| 96 | leukotriene metabolic process (GO:0006691) | 2.76119176 |
| 97 | neutrophil migration (GO:1990266) | 2.76078399 |
| 98 | positive thymic T cell selection (GO:0045059) | 2.76018322 |
| 99 | positive regulation of alpha-beta T cell proliferation (GO:0046641) | 2.75680468 |
| 100 | regulation of interleukin-1 beta secretion (GO:0050706) | 2.75586799 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 4.17638468 |
| 2 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 4.07895465 |
| 3 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 3.93981601 |
| 4 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 3.85625927 |
| 5 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 3.77147220 |
| 6 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 3.24235854 |
| 7 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 2.91056467 |
| 8 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 2.88213021 |
| 9 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.51109911 |
| 10 | MECOM_23826213_ChIP-Seq_KASUMI_Mouse | 2.40536304 |
| 11 | RUNX_20019798_ChIP-Seq_JUKART_Human | 2.38441449 |
| 12 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 2.37574647 |
| 13 | IRF8_27001747_Chip-Seq_BMDM_Mouse | 2.32753492 |
| 14 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 2.30884184 |
| 15 | MYB_26560356_Chip-Seq_TH2_Human | 2.17068478 |
| 16 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.97808269 |
| 17 | * POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.94736931 |
| 18 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.94147287 |
| 19 | SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.93656746 |
| 20 | SOX9_22984422_ChIP-ChIP_TESTIS_Rat | 1.92242650 |
| 21 | SPI1_23547873_ChIP-Seq_NB4_Human | 1.78853391 |
| 22 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 1.78548457 |
| 23 | GATA3_27048872_Chip-Seq_THYMUS_Human | 1.77941463 |
| 24 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.77929302 |
| 25 | GATA3_26560356_Chip-Seq_TH2_Human | 1.74993484 |
| 26 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 1.70599407 |
| 27 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.68243831 |
| 28 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.66183586 |
| 29 | VDR_24787735_ChIP-Seq_THP-1_Human | 1.59692308 |
| 30 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 1.56258802 |
| 31 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.54040812 |
| 32 | Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.51811291 |
| 33 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.50656656 |
| 34 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.49848887 |
| 35 | MYB_26560356_Chip-Seq_TH1_Human | 1.49444376 |
| 36 | STAT4_19710469_ChIP-ChIP_TH1__Mouse | 1.47142576 |
| 37 | CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human | 1.46338280 |
| 38 | TEAD4_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.45180587 |
| 39 | POU5F1_26923725_Chip-Seq_MESODERM_Mouse | 1.45180587 |
| 40 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.43995450 |
| 41 | SPI1_22096565_ChIP-ChIP_GC-B_Mouse | 1.42759405 |
| 42 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.42479805 |
| 43 | P300_19829295_ChIP-Seq_ESCs_Human | 1.41355511 |
| 44 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.35795513 |
| 45 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.35540655 |
| 46 | VDR_22108803_ChIP-Seq_LS180_Human | 1.33013757 |
| 47 | PRDM14_20953172_ChIP-Seq_ESCs_Human | 1.32464123 |
| 48 | IRF1_19129219_ChIP-ChIP_H3396_Human | 1.31690653 |
| 49 | * UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.31532914 |
| 50 | PPARG_20176806_ChIP-Seq_MACROPHAGES_Mouse | 1.31392874 |
| 51 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.29913890 |
| 52 | RUNX1_17652178_ChIP-ChIP_JURKAT_Human | 1.24979694 |
| 53 | SPI1_23127762_ChIP-Seq_K562_Human | 1.24288520 |
| 54 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.23528432 |
| 55 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.21251199 |
| 56 | FUS_26573619_Chip-Seq_HEK293_Human | 1.20509328 |
| 57 | FLI1_21867929_ChIP-Seq_TH2_Mouse | 1.20191682 |
| 58 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.18654813 |
| 59 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.17712068 |
| 60 | SCL_19346495_ChIP-Seq_HPC-7_Human | 1.17130446 |
| 61 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.15699784 |
| 62 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.15435021 |
| 63 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.14664908 |
| 64 | * CBP_20019798_ChIP-Seq_JUKART_Human | 1.12198853 |
| 65 | * IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.12198853 |
| 66 | SALL4_22934838_ChIP-ChIP_CD34+_Human | 1.11021512 |
| 67 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.09194624 |
| 68 | NOTCH1_21737748_ChIP-Seq_TLL_Human | 1.07981918 |
| 69 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.07389278 |
| 70 | EWS_26573619_Chip-Seq_HEK293_Human | 1.07138548 |
| 71 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.07033024 |
| 72 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.07015515 |
| 73 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.04473955 |
| 74 | TCF12/HEB_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.04341399 |
| 75 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.03396414 |
| 76 | TAL1_22897851_ChIP-Seq_JUKARTE6-1_Human | 1.02676774 |
| 77 | SMRT_27268052_Chip-Seq_Bcells_Human | 1.02085265 |
| 78 | CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.02024498 |
| 79 | GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human | 1.00580086 |
| 80 | GATA3_26560356_Chip-Seq_TH1_Human | 0.99936989 |
| 81 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 0.96170337 |
| 82 | * GATA3_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.96159629 |
| 83 | TAL1_21186366_ChIP-Seq_BM-HSCs_Mouse | 0.94786609 |
| 84 | * MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 0.92934838 |
| 85 | HOXB4_20404135_ChIP-ChIP_EML_Mouse | 0.92241449 |
| 86 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 0.91855472 |
| 87 | SMAD4_21799915_ChIP-Seq_A2780_Human | 0.91764242 |
| 88 | TCF3/E2A_22897851_ChIP-Seq_JUKARTE6-1_Human | 0.90856322 |
| 89 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.89595989 |
| 90 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 0.89073687 |
| 91 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 0.88939440 |
| 92 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 0.88849946 |
| 93 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.88136873 |
| 94 | TCF4_22108803_ChIP-Seq_LS180_Human | 0.87417226 |
| 95 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.87262906 |
| 96 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 0.87213756 |
| 97 | SOX2_19829295_ChIP-Seq_ESCs_Human | 0.87077146 |
| 98 | NANOG_19829295_ChIP-Seq_ESCs_Human | 0.87077146 |
| 99 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 0.87059146 |
| 100 | AR_25329375_ChIP-Seq_VCAP_Human | 0.86962518 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | MP0003724_increased_susceptibility_to | 5.76178171 |
| 2 | MP0000569_abnormal_digit_pigmentation | 5.10721557 |
| 3 | MP0005671_abnormal_response_to | 3.50923850 |
| 4 | MP0008260_abnormal_autophagy | 3.33372358 |
| 5 | MP0001835_abnormal_antigen_presentation | 3.30596974 |
| 6 | MP0003787_abnormal_imprinting | 3.01488066 |
| 7 | MP0009785_altered_susceptibility_to | 2.69165766 |
| 8 | MP0008877_abnormal_DNA_methylation | 2.63721658 |
| 9 | MP0001800_abnormal_humoral_immune | 2.56509536 |
| 10 | MP0002166_altered_tumor_susceptibility | 2.41075950 |
| 11 | MP0002723_abnormal_immune_serum | 2.26595630 |
| 12 | MP0002419_abnormal_innate_immunity | 2.26435544 |
| 13 | MP0005025_abnormal_response_to | 2.24539218 |
| 14 | MP0002420_abnormal_adaptive_immunity | 2.12745218 |
| 15 | MP0001819_abnormal_immune_cell | 2.08177338 |
| 16 | MP0004381_abnormal_hair_follicle | 2.06540684 |
| 17 | MP0005000_abnormal_immune_tolerance | 2.01421355 |
| 18 | MP0003436_decreased_susceptibility_to | 2.00937822 |
| 19 | MP0006082_CNS_inflammation | 2.00919016 |
| 20 | MP0003221_abnormal_cardiomyocyte_apopto | 1.99559026 |
| 21 | MP0002452_abnormal_antigen_presenting | 1.98845436 |
| 22 | MP0003656_abnormal_erythrocyte_physiolo | 1.97619176 |
| 23 | MP0003303_peritoneal_inflammation | 1.97495195 |
| 24 | MP0000685_abnormal_immune_system | 1.96112831 |
| 25 | MP0002277_abnormal_respiratory_mucosa | 1.95544890 |
| 26 | MP0004883_abnormal_blood_vessel | 1.94387908 |
| 27 | MP0003763_abnormal_thymus_physiology | 1.82911684 |
| 28 | MP0002006_tumorigenesis | 1.78263731 |
| 29 | MP0002132_abnormal_respiratory_system | 1.78166663 |
| 30 | MP0000015_abnormal_ear_pigmentation | 1.75596581 |
| 31 | MP0005464_abnormal_platelet_physiology | 1.73513654 |
| 32 | MP0009764_decreased_sensitivity_to | 1.66676995 |
| 33 | MP0002398_abnormal_bone_marrow | 1.64200036 |
| 34 | MP0000716_abnormal_immune_system | 1.62683187 |
| 35 | MP0002148_abnormal_hypersensitivity_rea | 1.61654197 |
| 36 | MP0004484_altered_response_of | 1.59318731 |
| 37 | MP0003121_genomic_imprinting | 1.55016008 |
| 38 | MP0001790_abnormal_immune_system | 1.50827692 |
| 39 | MP0005387_immune_system_phenotype | 1.50827692 |
| 40 | MP0002405_respiratory_system_inflammati | 1.48953186 |
| 41 | MP0005075_abnormal_melanosome_morpholog | 1.47245142 |
| 42 | MP0002722_abnormal_immune_system | 1.46014844 |
| 43 | MP0000689_abnormal_spleen_morphology | 1.45472034 |
| 44 | MP0001845_abnormal_inflammatory_respons | 1.43574999 |
| 45 | MP0005174_abnormal_tail_pigmentation | 1.40431773 |
| 46 | MP0003172_abnormal_lysosome_physiology | 1.36740756 |
| 47 | MP0003183_abnormal_peptide_metabolism | 1.34130581 |
| 48 | MP0003866_abnormal_defecation | 1.33886190 |
| 49 | MP0005451_abnormal_body_composition | 1.31919801 |
| 50 | MP0000703_abnormal_thymus_morphology | 1.29151168 |
| 51 | MP0005164_abnormal_response_to | 1.27648122 |
| 52 | MP0005310_abnormal_salivary_gland | 1.25876219 |
| 53 | MP0002429_abnormal_blood_cell | 1.19890128 |
| 54 | MP0000858_altered_metastatic_potential | 1.18980845 |
| 55 | MP0005410_abnormal_fertilization | 1.18462517 |
| 56 | MP0000465_gastrointestinal_hemorrhage | 1.13357318 |
| 57 | MP0009765_abnormal_xenobiotic_induced | 1.09036895 |
| 58 | MP0003828_pulmonary_edema | 1.05664936 |
| 59 | MP0003195_calcinosis | 1.05324611 |
| 60 | MP0001533_abnormal_skeleton_physiology | 1.03895798 |
| 61 | MP0006054_spinal_hemorrhage | 1.03267658 |
| 62 | MP0008469_abnormal_protein_level | 1.02997881 |
| 63 | MP0002332_abnormal_exercise_endurance | 1.01303389 |
| 64 | MP0000427_abnormal_hair_cycle | 0.93710921 |
| 65 | MP0005389_reproductive_system_phenotype | 0.92967051 |
| 66 | MP0002736_abnormal_nociception_after | 0.90701454 |
| 67 | MP0003300_gastrointestinal_ulcer | 0.89401872 |
| 68 | MP0002909_abnormal_adrenal_gland | 0.86096335 |
| 69 | MP0010155_abnormal_intestine_physiology | 0.85033375 |
| 70 | MP0002095_abnormal_skin_pigmentation | 0.84324436 |
| 71 | MP0009763_increased_sensitivity_to | 0.83395021 |
| 72 | MP0001968_abnormal_touch/_nociception | 0.78842868 |
| 73 | MP0002102_abnormal_ear_morphology | 0.78231162 |
| 74 | MP0009333_abnormal_splenocyte_physiolog | 0.76184151 |
| 75 | MP0001545_abnormal_hematopoietic_system | 0.75920794 |
| 76 | MP0005397_hematopoietic_system_phenotyp | 0.75920794 |
| 77 | MP0004142_abnormal_muscle_tone | 0.75806437 |
| 78 | MP0003075_altered_response_to | 0.75215831 |
| 79 | MP0002928_abnormal_bile_duct | 0.74430573 |
| 80 | MP0001919_abnormal_reproductive_system | 0.73209078 |
| 81 | MP0005376_homeostasis/metabolism_phenot | 0.72056622 |
| 82 | MP0004947_skin_inflammation | 0.70155697 |
| 83 | MP0008004_abnormal_stomach_pH | 0.68310086 |
| 84 | MP0005084_abnormal_gallbladder_morpholo | 0.67749036 |
| 85 | MP0003122_maternal_imprinting | 0.67537202 |
| 86 | MP0003786_premature_aging | 0.66867085 |
| 87 | MP0003191_abnormal_cellular_cholesterol | 0.65457025 |
| 88 | MP0003045_fibrosis | 0.65201785 |
| 89 | MP0005166_decreased_susceptibility_to | 0.64250754 |
| 90 | MP0002160_abnormal_reproductive_system | 0.64096849 |
| 91 | MP0008874_decreased_physiological_sensi | 0.63588410 |
| 92 | MP0003448_altered_tumor_morphology | 0.63388659 |
| 93 | MP0004147_increased_porphyrin_level | 0.61582600 |
| 94 | MP0003632_abnormal_nervous_system | 0.59421791 |
| 95 | MP0003878_abnormal_ear_physiology | 0.55337808 |
| 96 | MP0005377_hearing/vestibular/ear_phenot | 0.55337808 |
| 97 | MP0000249_abnormal_blood_vessel | 0.55005621 |
| 98 | MP0005584_abnormal_enzyme/coenzyme_acti | 0.51868335 |
| 99 | MP0000371_diluted_coat_color | 0.51217845 |
| 100 | MP0004130_abnormal_muscle_cell | 0.50556804 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | T lymphocytopenia (HP:0005403) | 5.56057157 |
| 2 | Abnormality of T cell number (HP:0011839) | 5.40743060 |
| 3 | Parkinsonism with favorable response to dopaminergic medication (HP:0002548) | 5.22693537 |
| 4 | Recurrent bacterial skin infections (HP:0005406) | 5.20549131 |
| 5 | Retrobulbar optic neuritis (HP:0100654) | 5.18667831 |
| 6 | Optic neuritis (HP:0100653) | 5.18667831 |
| 7 | Orchitis (HP:0100796) | 4.81536836 |
| 8 | Myositis (HP:0100614) | 4.76088705 |
| 9 | Recurrent abscess formation (HP:0002722) | 4.69118540 |
| 10 | Gastrointestinal infarctions (HP:0005244) | 4.29169021 |
| 11 | Elevated erythrocyte sedimentation rate (HP:0003565) | 4.25966249 |
| 12 | Eczematoid dermatitis (HP:0000976) | 4.23160008 |
| 13 | Keratoconjunctivitis sicca (HP:0001097) | 3.98279699 |
| 14 | Stomatitis (HP:0010280) | 3.82143984 |
| 15 | Encephalitis (HP:0002383) | 3.69882092 |
| 16 | Keratoconjunctivitis (HP:0001096) | 3.62122597 |
| 17 | Recurrent fungal infections (HP:0002841) | 3.50886500 |
| 18 | Recurrent skin infections (HP:0001581) | 3.47013387 |
| 19 | Recurrent gram-negative bacterial infections (HP:0005420) | 3.38996624 |
| 20 | Abnormality of macrophages (HP:0004311) | 3.36666569 |
| 21 | Abnormality of T cells (HP:0002843) | 3.36444736 |
| 22 | Resting tremor (HP:0002322) | 3.34448018 |
| 23 | Chronic mucocutaneous candidiasis (HP:0002728) | 3.30293243 |
| 24 | Recurrent cutaneous fungal infections (HP:0011370) | 3.30293243 |
| 25 | Peritonitis (HP:0002586) | 3.25014661 |
| 26 | Leukocytosis (HP:0001974) | 3.21217903 |
| 27 | Increased IgM level (HP:0003496) | 3.20058544 |
| 28 | Arterial thrombosis (HP:0004420) | 3.16423687 |
| 29 | Autoimmune hemolytic anemia (HP:0001890) | 3.04439251 |
| 30 | Gingival bleeding (HP:0000225) | 3.01613664 |
| 31 | Eosinophilia (HP:0001880) | 2.99247771 |
| 32 | Abnormal delayed hypersensitivity skin test (HP:0002963) | 2.98230472 |
| 33 | Gingivitis (HP:0000230) | 2.91881065 |
| 34 | Anorexia (HP:0002039) | 2.88390645 |
| 35 | Abnormality of eosinophils (HP:0001879) | 2.86842736 |
| 36 | Meningitis (HP:0001287) | 2.81327476 |
| 37 | Chest pain (HP:0100749) | 2.81001909 |
| 38 | Amyotrophic lateral sclerosis (HP:0007354) | 2.76385339 |
| 39 | Vasculitis (HP:0002633) | 2.74754166 |
| 40 | IgG deficiency (HP:0004315) | 2.74043933 |
| 41 | Gangrene (HP:0100758) | 2.73112450 |
| 42 | Acute hepatic failure (HP:0006554) | 2.73076650 |
| 43 | Hemoptysis (HP:0002105) | 2.73061246 |
| 44 | Mediastinal lymphadenopathy (HP:0100721) | 2.65560858 |
| 45 | Granulocytopenia (HP:0001913) | 2.64857290 |
| 46 | Thyroiditis (HP:0100646) | 2.62652566 |
| 47 | Chronic obstructive pulmonary disease (HP:0006510) | 2.62092068 |
| 48 | Obstructive lung disease (HP:0006536) | 2.62092068 |
| 49 | Aplastic anemia (HP:0001915) | 2.58826521 |
| 50 | Autoimmune thrombocytopenia (HP:0001973) | 2.57506218 |
| 51 | Spontaneous hematomas (HP:0007420) | 2.52761939 |
| 52 | Postural instability (HP:0002172) | 2.50059263 |
| 53 | Palpebral edema (HP:0100540) | 2.48743707 |
| 54 | Recurrent bronchitis (HP:0002837) | 2.46929476 |
| 55 | Hypoproteinemia (HP:0003075) | 2.46373243 |
| 56 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.43070329 |
| 57 | Absent/shortened dynein arms (HP:0200106) | 2.43070329 |
| 58 | Urticaria (HP:0001025) | 2.39179180 |
| 59 | Slow saccadic eye movements (HP:0000514) | 2.33881375 |
| 60 | Recurrent viral infections (HP:0004429) | 2.33510603 |
| 61 | Pulmonary embolism (HP:0002204) | 2.31070344 |
| 62 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.30592342 |
| 63 | Episodic fever (HP:0001954) | 2.29573072 |
| 64 | Genetic anticipation (HP:0003743) | 2.24504995 |
| 65 | Severe combined immunodeficiency (HP:0004430) | 2.21582189 |
| 66 | Pulmonary infiltrates (HP:0002113) | 2.18539287 |
| 67 | Abnormality of the peritoneum (HP:0002585) | 2.15024032 |
| 68 | Papillary thyroid carcinoma (HP:0002895) | 2.11778857 |
| 69 | Epistaxis (HP:0000421) | 2.08126968 |
| 70 | Abnormality of the columella (HP:0009929) | 2.04245432 |
| 71 | Menstrual irregularities (HP:0000858) | 2.01791169 |
| 72 | Subacute progressive viral hepatitis (HP:0006572) | 1.97871529 |
| 73 | Chronic diarrhea (HP:0002028) | 1.95799490 |
| 74 | Abnormality of the pleura (HP:0002103) | 1.93607425 |
| 75 | Agitation (HP:0000713) | 1.92573516 |
| 76 | Pelvic girdle muscle weakness (HP:0003749) | 1.88763768 |
| 77 | Keratitis (HP:0000491) | 1.88671939 |
| 78 | Abnormality of T cell physiology (HP:0011840) | 1.84006551 |
| 79 | Decreased central vision (HP:0007663) | 1.83662260 |
| 80 | Glomerulopathy (HP:0100820) | 1.82203096 |
| 81 | Stomach cancer (HP:0012126) | 1.80120239 |
| 82 | Abnormality of the endocardium (HP:0004306) | 1.79140267 |
| 83 | Attenuation of retinal blood vessels (HP:0007843) | 1.79096347 |
| 84 | IgM deficiency (HP:0002850) | 1.78834215 |
| 85 | Vertigo (HP:0002321) | 1.77804460 |
| 86 | Hypochromic microcytic anemia (HP:0004840) | 1.76416603 |
| 87 | Hypergammaglobulinemia (HP:0010702) | 1.76114990 |
| 88 | Abnormal respiratory epithelium morphology (HP:0012253) | 1.75314922 |
| 89 | Abnormal respiratory motile cilium morphology (HP:0005938) | 1.75314922 |
| 90 | Abnormal sex determination (HP:0012244) | 1.74824030 |
| 91 | Sex reversal (HP:0012245) | 1.74824030 |
| 92 | Acne (HP:0001061) | 1.74022450 |
| 93 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.72758949 |
| 94 | Polyneuropathy (HP:0001271) | 1.72416635 |
| 95 | Neoplasm of the tracheobronchial system (HP:0100552) | 1.72028398 |
| 96 | Microcytic anemia (HP:0001935) | 1.70745364 |
| 97 | Arthropathy (HP:0003040) | 1.68185420 |
| 98 | Thyroid carcinoma (HP:0002890) | 1.67561629 |
| 99 | Thoracolumbar scoliosis (HP:0002944) | 1.66572108 |
| 100 | Abnormal ciliary motility (HP:0012262) | 1.65776342 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | TXK | 4.00520916 |
| 2 | BLK | 3.58157748 |
| 3 | RIPK4 | 3.52031438 |
| 4 | IRAK4 | 2.72434058 |
| 5 | FES | 2.44904269 |
| 6 | TAOK3 | 2.38119932 |
| 7 | GRK6 | 2.36248850 |
| 8 | CSK | 2.34626828 |
| 9 | MAP2K3 | 2.33938617 |
| 10 | FRK | 2.26276535 |
| 11 | IKBKE | 2.06998529 |
| 12 | FGR | 1.98791610 |
| 13 | TESK2 | 1.95905701 |
| 14 | PIK3CG | 1.90844374 |
| 15 | MAP4K1 | 1.88147730 |
| 16 | IRAK1 | 1.87096468 |
| 17 | MAP3K12 | 1.81627264 |
| 18 | MAP3K5 | 1.74035896 |
| 19 | MAP3K6 | 1.73641799 |
| 20 | EPHA3 | 1.71354555 |
| 21 | SYK | 1.66425598 |
| 22 | EPHB1 | 1.60307180 |
| 23 | JAK3 | 1.55408417 |
| 24 | ZAP70 | 1.53438635 |
| 25 | MAP3K2 | 1.51635265 |
| 26 | GRK5 | 1.49662366 |
| 27 | IRAK2 | 1.41491238 |
| 28 | PLK2 | 1.35663862 |
| 29 | PTK2B | 1.35025228 |
| 30 | ITK | 1.30658743 |
| 31 | WNK3 | 1.29783606 |
| 32 | TYK2 | 1.29558104 |
| 33 | SGK2 | 1.29080202 |
| 34 | WNK1 | 1.28222820 |
| 35 | MAP3K11 | 1.26879577 |
| 36 | LYN | 1.23195865 |
| 37 | BTK | 1.21739527 |
| 38 | MAP2K4 | 1.20639752 |
| 39 | JAK2 | 1.19365420 |
| 40 | MATK | 1.18186977 |
| 41 | MAP4K2 | 1.16969983 |
| 42 | YES1 | 1.10775571 |
| 43 | HCK | 1.09121725 |
| 44 | BMPR2 | 1.05168801 |
| 45 | MAP2K7 | 0.99029195 |
| 46 | DYRK3 | 0.97967142 |
| 47 | MAP3K3 | 0.97624262 |
| 48 | ADRBK2 | 0.96537532 |
| 49 | TEC | 0.94926333 |
| 50 | ACVR1B | 0.94343040 |
| 51 | MARK3 | 0.92159017 |
| 52 | SGK223 | 0.91371757 |
| 53 | SGK494 | 0.91371757 |
| 54 | ERBB2 | 0.90772171 |
| 55 | PINK1 | 0.90727573 |
| 56 | LCK | 0.90329208 |
| 57 | KDR | 0.89111174 |
| 58 | MAP3K1 | 0.85551838 |
| 59 | NLK | 0.84870384 |
| 60 | PIM1 | 0.84412898 |
| 61 | LRRK2 | 0.81322964 |
| 62 | OXSR1 | 0.81054423 |
| 63 | TAOK1 | 0.79453185 |
| 64 | TNK2 | 0.78010031 |
| 65 | DYRK1A | 0.76400895 |
| 66 | BCR | 0.76008142 |
| 67 | RAF1 | 0.70230681 |
| 68 | RPS6KA5 | 0.70052361 |
| 69 | FGFR3 | 0.68763032 |
| 70 | CLK1 | 0.67303571 |
| 71 | SGK3 | 0.67068665 |
| 72 | GRK7 | 0.65331252 |
| 73 | CDK19 | 0.64895156 |
| 74 | PAK3 | 0.63074655 |
| 75 | NEK9 | 0.61911549 |
| 76 | DYRK1B | 0.61054609 |
| 77 | NUAK1 | 0.59661541 |
| 78 | CAMKK2 | 0.56051133 |
| 79 | PRKCQ | 0.55269158 |
| 80 | STK38L | 0.55076974 |
| 81 | FER | 0.51584891 |
| 82 | CSF1R | 0.49493007 |
| 83 | KSR2 | 0.47031626 |
| 84 | MAP3K4 | 0.46575558 |
| 85 | FYN | 0.44781431 |
| 86 | KIT | 0.43790091 |
| 87 | JAK1 | 0.43716337 |
| 88 | SGK1 | 0.43546555 |
| 89 | EGFR | 0.43380231 |
| 90 | BRD4 | 0.42533376 |
| 91 | DAPK2 | 0.41147776 |
| 92 | DYRK2 | 0.41034363 |
| 93 | STK16 | 0.40673696 |
| 94 | STK4 | 0.40357390 |
| 95 | ADRBK1 | 0.40274909 |
| 96 | RET | 0.37599898 |
| 97 | CAMK4 | 0.37362848 |
| 98 | MAP3K14 | 0.37078317 |
| 99 | STK11 | 0.33811972 |
| 100 | TAF1 | 0.32841189 |

| Rank | Gene Set | Z-score |
|---|---|---|
| 1 | Natural killer cell mediated cytotoxicity_Homo sapiens_hsa04650 | 3.13818238 |
| 2 | Primary immunodeficiency_Homo sapiens_hsa05340 | 2.95445470 |
| 3 | Leishmaniasis_Homo sapiens_hsa05140 | 2.70959120 |
| 4 | NOD-like receptor signaling pathway_Homo sapiens_hsa04621 | 2.47774417 |
| 5 | Osteoclast differentiation_Homo sapiens_hsa04380 | 2.46399775 |
| 6 | Toll-like receptor signaling pathway_Homo sapiens_hsa04620 | 2.34106214 |
| 7 | Legionellosis_Homo sapiens_hsa05134 | 2.28156448 |
| 8 | Measles_Homo sapiens_hsa05162 | 2.27845935 |
| 9 | Fc gamma R-mediated phagocytosis_Homo sapiens_hsa04666 | 2.27404168 |
| 10 | T cell receptor signaling pathway_Homo sapiens_hsa04660 | 2.17636761 |
| 11 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 2.13469264 |
| 12 | Tuberculosis_Homo sapiens_hsa05152 | 2.09138705 |
| 13 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 2.04103975 |
| 14 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.97513075 |
| 15 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | 1.91528568 |
| 16 | Malaria_Homo sapiens_hsa05144 | 1.87500260 |
| 17 | Proteasome_Homo sapiens_hsa03050 | 1.86167915 |
| 18 | Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 1.83535590 |
| 19 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 1.83496918 |
| 20 | Antigen processing and presentation_Homo sapiens_hsa04612 | 1.71775768 |
| 21 | Chemokine signaling pathway_Homo sapiens_hsa04062 | 1.54566795 |
| 22 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 1.44766162 |
| 23 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 1.43338919 |
| 24 | Salmonella infection_Homo sapiens_hsa05132 | 1.37991926 |
| 25 | Phagosome_Homo sapiens_hsa04145 | 1.37645763 |
| 26 | Graft-versus-host disease_Homo sapiens_hsa05332 | 1.37587113 |
| 27 | B cell receptor signaling pathway_Homo sapiens_hsa04662 | 1.37410911 |
| 28 | Chagas disease (American trypanosomiasis)_Homo sapiens_hsa05142 | 1.37081729 |
| 29 | Fc epsilon RI signaling pathway_Homo sapiens_hsa04664 | 1.36852409 |
| 30 | Apoptosis_Homo sapiens_hsa04210 | 1.34603934 |
| 31 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 1.33823072 |
| 32 | Influenza A_Homo sapiens_hsa05164 | 1.31675160 |
| 33 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 1.30596044 |
| 34 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 1.29659000 |
| 35 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 1.28793915 |
| 36 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.28605975 |
| 37 | SNARE interactions in vesicular transport_Homo sapiens_hsa04130 | 1.26415065 |
| 38 | Allograft rejection_Homo sapiens_hsa05330 | 1.20637544 |
| 39 | Shigellosis_Homo sapiens_hsa05131 | 1.19924275 |
| 40 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 1.17915445 |
| 41 | TNF signaling pathway_Homo sapiens_hsa04668 | 1.14037196 |
| 42 | Rheumatoid arthritis_Homo sapiens_hsa05323 | 1.04498607 |
| 43 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.04128982 |
| 44 | Herpes simplex infection_Homo sapiens_hsa05168 | 1.03484197 |
| 45 | Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa05120 | 1.02799371 |
| 46 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.01685191 |
| 47 | Amyotrophic lateral sclerosis (ALS)_Homo sapiens_hsa05014 | 1.00531323 |
| 48 | Hepatitis B_Homo sapiens_hsa05161 | 0.98932732 |
| 49 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.94033834 |
| 50 | Parkinsons disease_Homo sapiens_hsa05012 | 0.93905790 |
| 51 | Platelet activation_Homo sapiens_hsa04611 | 0.87848676 |
| 52 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.85984127 |
| 53 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.82610268 |
| 54 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.78571326 |
| 55 | Pertussis_Homo sapiens_hsa05133 | 0.74982742 |
| 56 | Morphine addiction_Homo sapiens_hsa05032 | 0.73795644 |
| 57 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 0.72009180 |
| 58 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.70666291 |
| 59 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.69089454 |
| 60 | Olfactory transduction_Homo sapiens_hsa04740 | 0.67748700 |
| 61 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.64736904 |
| 62 | Caffeine metabolism_Homo sapiens_hsa00232 | 0.64570619 |
| 63 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.63209674 |
| 64 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.59683303 |
| 65 | Hepatitis C_Homo sapiens_hsa05160 | 0.59462208 |
| 66 | Alzheimers disease_Homo sapiens_hsa05010 | 0.59330861 |
| 67 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.58375590 |
| 68 | Collecting duct acid secretion_Homo sapiens_hsa04966 | 0.58211863 |
| 69 | Nitrogen metabolism_Homo sapiens_hsa00910 | 0.58099030 |
| 70 | Endocytosis_Homo sapiens_hsa04144 | 0.57064253 |
| 71 | Circadian rhythm_Homo sapiens_hsa04710 | 0.54091043 |
| 72 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.51408699 |
| 73 | Viral myocarditis_Homo sapiens_hsa05416 | 0.48980555 |
| 74 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.47849797 |
| 75 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.46472603 |
| 76 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.46471362 |
| 77 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.46418616 |
| 78 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 0.46303006 |
| 79 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.46189827 |
| 80 | GABAergic synapse_Homo sapiens_hsa04727 | 0.45826502 |
| 81 | Alcoholism_Homo sapiens_hsa05034 | 0.44474127 |
| 82 | Systemic lupus erythematosus_Homo sapiens_hsa05322 | 0.44055360 |
| 83 | Taste transduction_Homo sapiens_hsa04742 | 0.43038305 |
| 84 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.41500200 |
| 85 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.39901008 |
| 86 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.38208347 |
| 87 | Phototransduction_Homo sapiens_hsa04744 | 0.37134140 |
| 88 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.36789469 |
| 89 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.35511072 |
| 90 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.34777715 |
| 91 | Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa04750 | 0.34322225 |
| 92 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.32992205 |
| 93 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.32388401 |
| 94 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.31743086 |
| 95 | Retrograde endocannabinoid signaling_Homo sapiens_hsa04723 | 0.31254597 |
| 96 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.30291220 |
| 97 | Epstein-Barr virus infection_Homo sapiens_hsa05169 | 0.29851663 |
| 98 | African trypanosomiasis_Homo sapiens_hsa05143 | 0.29774774 |
| 99 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 0.28437895 |
| 100 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.27375468 |

