CSNK2A2

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1regulation of DNA endoreduplication (GO:0032875)4.10403521
2ribosome assembly (GO:0042255)4.04772082
3synapsis (GO:0007129)3.97573753
4DNA strand elongation involved in DNA replication (GO:0006271)3.96712869
5RNA phosphodiester bond hydrolysis, exonucleolytic (GO:0090503)3.92765087
6DNA strand elongation (GO:0022616)3.87691309
7proteasome assembly (GO:0043248)3.81778499
8nuclear pore complex assembly (GO:0051292)3.76708889
9mitotic sister chromatid segregation (GO:0000070)3.72069571
10protein localization to kinetochore (GO:0034501)3.70136248
11double-strand break repair via nonhomologous end joining (GO:0006303)3.69524280
12non-recombinational repair (GO:0000726)3.69524280
13somatic diversification of immune receptors via somatic mutation (GO:0002566)3.67524568
14somatic hypermutation of immunoglobulin genes (GO:0016446)3.67524568
15somatic recombination of immunoglobulin genes involved in immune response (GO:0002204)3.67449220
16somatic diversification of immunoglobulins involved in immune response (GO:0002208)3.67449220
17isotype switching (GO:0045190)3.67449220
18nuclear pore organization (GO:0006999)3.63479826
19sister chromatid segregation (GO:0000819)3.60349753
20telomere maintenance via semi-conservative replication (GO:0032201)3.52506264
21IMP biosynthetic process (GO:0006188)3.47660297
22establishment of integrated proviral latency (GO:0075713)3.41248579
23* spindle checkpoint (GO:0031577)3.39619137
24DNA ligation (GO:0006266)3.37348167
25negative regulation of DNA damage response, signal transduction by p53 class mediator (GO:0043518)3.37198992
26somatic recombination of immunoglobulin gene segments (GO:0016447)3.34249708
27replication fork processing (GO:0031297)3.33468584
28DNA replication-independent nucleosome assembly (GO:0006336)3.33206865
29DNA replication-independent nucleosome organization (GO:0034724)3.33206865
30sister chromatid cohesion (GO:0007062)3.33015830
31* mitotic spindle checkpoint (GO:0071174)3.30336235
32attachment of spindle microtubules to kinetochore (GO:0008608)3.28788422
33negative regulation of chromosome segregation (GO:0051985)3.28530857
34negative regulation of sister chromatid segregation (GO:0033046)3.27907610
35negative regulation of mitotic metaphase/anaphase transition (GO:0045841)3.27907610
36negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)3.27907610
37negative regulation of mitotic sister chromatid segregation (GO:0033048)3.27907610
38negative regulation of mitotic sister chromatid separation (GO:2000816)3.27907610
39establishment of skin barrier (GO:0061436)3.24536286
40regulation of chromosome segregation (GO:0051983)3.23082118
41protein localization to chromosome, centromeric region (GO:0071459)3.22501772
42pore complex assembly (GO:0046931)3.21880534
43regulation of mitotic metaphase/anaphase transition (GO:0030071)3.20201278
44regulation of metaphase/anaphase transition of cell cycle (GO:1902099)3.20201278
45regulation of attachment of spindle microtubules to kinetochore (GO:0051988)3.17350854
46DNA unwinding involved in DNA replication (GO:0006268)3.15768890
47regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051439)3.13518842
48regulation of mitotic sister chromatid separation (GO:0010965)3.12889769
49regulation of mitotic sister chromatid segregation (GO:0033047)3.12889769
50regulation of sister chromatid segregation (GO:0033045)3.12889769
51purine nucleobase biosynthetic process (GO:0009113)3.11203736
52somatic diversification of immune receptors via germline recombination within a single locus (GO:0003.09452945
53somatic cell DNA recombination (GO:0016444)3.09452945
54response to X-ray (GO:0010165)3.08987707
55DNA replication-dependent nucleosome assembly (GO:0006335)3.08365113
56DNA replication-dependent nucleosome organization (GO:0034723)3.08365113
57somatic diversification of immunoglobulins (GO:0016445)3.05324245
58regulation of translational termination (GO:0006449)3.05198499
59regulation of water loss via skin (GO:0033561)3.04973615
60negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle (GO:0051436)3.04599908
61protein K6-linked ubiquitination (GO:0085020)3.03969334
62rRNA methylation (GO:0031167)3.03310383
63mitotic spindle assembly checkpoint (GO:0007094)3.02534119
64regulation of centrosome cycle (GO:0046605)3.01676060
65regulation of nuclear cell cycle DNA replication (GO:0033262)3.01005533
66tRNA aminoacylation for protein translation (GO:0006418)2.98805806
67spindle assembly checkpoint (GO:0071173)2.97540819
68anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.97246907
69telomere maintenance via telomere lengthening (GO:0010833)2.96029029
70IMP metabolic process (GO:0046040)2.96010327
71rRNA modification (GO:0000154)2.94994834
72negative regulation of DNA recombination (GO:0045910)2.94890736
73mitotic chromosome condensation (GO:0007076)2.94674199
74mitotic metaphase plate congression (GO:0007080)2.94604604
75negative regulation of mRNA metabolic process (GO:1903312)2.94203515
76folic acid-containing compound biosynthetic process (GO:0009396)2.93764709
77nucleobase biosynthetic process (GO:0046112)2.93745754
78amino acid activation (GO:0043038)2.93301872
79tRNA aminoacylation (GO:0043039)2.93301872
80regulation of mitotic spindle checkpoint (GO:1903504)2.84911709
81regulation of mitotic cell cycle spindle assembly checkpoint (GO:0090266)2.84911709
82positive regulation of mitotic sister chromatid separation (GO:1901970)2.77118842
83positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.77118842
84positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.77118842
85establishment of chromosome localization (GO:0051303)2.74086442
86meiotic chromosome segregation (GO:0045132)2.71766553
87negative regulation by host of viral transcription (GO:0043922)2.70698013
88negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class 2.66909892
89negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902254)2.64426559
90piRNA metabolic process (GO:0034587)2.59876066
91metaphase plate congression (GO:0051310)2.58022496
92microtubule depolymerization (GO:0007019)2.57651834
93regulation of gene silencing by RNA (GO:0060966)2.57431724
94regulation of posttranscriptional gene silencing (GO:0060147)2.57431724
95regulation of gene silencing by miRNA (GO:0060964)2.57431724
96poly(A)+ mRNA export from nucleus (GO:0016973)2.56823852
97negative regulation of signal transduction by p53 class mediator (GO:1901797)2.56532224
98kinetochore organization (GO:0051383)2.54498929
99regulation of double-strand break repair via homologous recombination (GO:0010569)2.51256267
100notochord development (GO:0030903)2.49200679
101positive regulation of monocyte chemotaxis (GO:0090026)2.47677102
102DNA double-strand break processing (GO:0000729)2.45916159
103interferon-gamma secretion (GO:0072643)2.42804443
104paraxial mesoderm development (GO:0048339)2.42238057
105lipoxygenase pathway (GO:0019372)2.39481232
106kinetochore assembly (GO:0051382)2.38955061
107response to peptidoglycan (GO:0032494)2.38692917
108DNA replication checkpoint (GO:0000076)2.34200329
109superoxide anion generation (GO:0042554)2.33114457
110negative regulation of mast cell activation (GO:0033004)2.32351936
111DNA catabolic process, exonucleolytic (GO:0000738)2.29857319
112neutrophil activation involved in immune response (GO:0002283)2.27988072
113regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:00450912.26182221
114RNA-dependent DNA replication (GO:0006278)2.26140978
115synaptonemal complex assembly (GO:0007130)2.25076516
116positive regulation of chromosome segregation (GO:0051984)2.24020261
117regulation of double-strand break repair (GO:2000779)2.23620993
118regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator 2.23535188
119cellular response to gamma radiation (GO:0071480)2.23026839
120mitotic nuclear envelope disassembly (GO:0007077)2.22969933
121regulation of intrinsic apoptotic signaling pathway by p53 class mediator (GO:1902253)2.22144753
122chromatin remodeling at centromere (GO:0031055)2.20652891
123negative regulation of DNA-dependent DNA replication (GO:2000104)2.19699348
124monoubiquitinated protein deubiquitination (GO:0035520)2.16417936
125CENP-A containing nucleosome assembly (GO:0034080)2.16164788
126positive regulation of leukocyte apoptotic process (GO:2000108)2.14588893
127DNA synthesis involved in DNA repair (GO:0000731)2.14204195
128single strand break repair (GO:0000012)2.13590872
129mitotic sister chromatid cohesion (GO:0007064)2.13443398
130synaptonemal complex organization (GO:0070193)2.13120678
131regulation of cell proliferation involved in kidney development (GO:1901722)2.12875436
132regulation of fibroblast apoptotic process (GO:2000269)2.11858674
133keratinocyte differentiation (GO:0030216)2.11716515
134positive regulation of T cell apoptotic process (GO:0070234)2.11503456
135heterochromatin organization (GO:0070828)2.10549391
136regulation of dendritic cell antigen processing and presentation (GO:0002604)2.10446778
137dendritic cell chemotaxis (GO:0002407)2.09860420
138eosinophil chemotaxis (GO:0048245)2.09596296
139nuclear envelope disassembly (GO:0051081)2.09485336
140membrane disassembly (GO:0030397)2.09485336
141natural killer cell mediated cytotoxicity (GO:0042267)2.08133555
142natural killer cell mediated immunity (GO:0002228)2.08133555
143regulation of spindle checkpoint (GO:0090231)2.06224637
144detection of other organism (GO:0098543)2.05366114
145regulation of vitamin D biosynthetic process (GO:0060556)2.04535367
146histone exchange (GO:0043486)2.04220469
147telomere maintenance via recombination (GO:0000722)2.04127644
148regulation of Wnt signaling pathway involved in heart development (GO:0003307)2.04096788
149chromosome organization involved in meiosis (GO:0070192)2.02480194
150granulocyte activation (GO:0036230)2.02094532
151regulation of transcription from RNA polymerase I promoter (GO:0006356)2.01860270
152detection of bacterium (GO:0016045)2.00884044
153positive regulation of syncytium formation by plasma membrane fusion (GO:0060143)2.00805879
154negative regulation of skeletal muscle tissue development (GO:0048642)2.00275178
155regulation of centriole replication (GO:0046599)2.00126796
156regulation of interleukin-8 secretion (GO:2000482)1.99741681
157desmosome organization (GO:0002934)1.98336801
158regulation of meiosis I (GO:0060631)1.98314574
159myeloid dendritic cell activation (GO:0001773)1.98196598
160DNA replication initiation (GO:0006270)1.98125754
161positive regulation of DNA-templated transcription, initiation (GO:2000144)1.96833651
162dendritic cell migration (GO:0036336)1.96453963
163mitotic recombination (GO:0006312)1.95047562
164chromosome segregation (GO:0007059)1.94604353
165mismatch repair (GO:0006298)1.93119679
166mitotic G2/M transition checkpoint (GO:0044818)1.92034561
167cellular response to ionizing radiation (GO:0071479)1.91629836
168regulation of hippo signaling (GO:0035330)1.91292678
169mRNA export from nucleus (GO:0006406)1.91095736
170maintenance of fidelity involved in DNA-dependent DNA replication (GO:0045005)1.90584032

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human7.61917061
2TP63_17297297_ChIP-ChIP_HaCaT_Human4.04991861
3RBPJ_22232070_ChIP-Seq_NCS_Mouse2.97657356
4IRF8_21731497_ChIP-ChIP_J774_Mouse2.95176277
5TP63_19390658_ChIP-ChIP_HaCaT_Human2.91854084
6BP1_19119308_ChIP-ChIP_Hs578T_Human2.90254484
7MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse2.82153004
8EGR1_19374776_ChIP-ChIP_THP-1_Human2.77309565
9FOXM1_23109430_ChIP-Seq_U2OS_Human2.75573240
10E2F4_17652178_ChIP-ChIP_JURKAT_Human2.73615052
11FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.63035371
12IRF8_22096565_ChIP-ChIP_GC-B_Human2.55703313
13* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.51143472
14NOTCH1_17114293_ChIP-ChIP_T-ALL_Human2.24914374
15* MYC_18555785_ChIP-Seq_MESCs_Mouse2.17393779
16ELK1_19687146_ChIP-ChIP_HELA_Human2.11069394
17FOXP3_17237761_ChIP-ChIP_TREG_Mouse2.06550413
18HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human2.00092544
19SALL1_21062744_ChIP-ChIP_HESCs_Human1.84563325
20EST1_17652178_ChIP-ChIP_JURKAT_Human1.83483655
21E2F1_21310950_ChIP-Seq_MCF-7_Human1.75195352
22MYC_19079543_ChIP-ChIP_MESCs_Mouse1.72076548
23HCFC1_20581084_ChIP-Seq_MESCs_Mouse1.71172979
24SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.69235792
25STAT3_20064451_ChIP-Seq_CD4+T_Mouse1.68945382
26MYCN_21190229_ChIP-Seq_SHEP-21N_Human1.68148489
27FLI1_27457419_Chip-Seq_LIVER_Mouse1.66202763
28MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.65650253
29ZNF274_21170338_ChIP-Seq_K562_Hela1.64780910
30MYC_19030024_ChIP-ChIP_MESCs_Mouse1.61679451
31EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse1.60994133
32KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.56953911
33GABP_17652178_ChIP-ChIP_JURKAT_Human1.56421218
34E2F1_18555785_ChIP-Seq_MESCs_Mouse1.54272193
35MYC_18940864_ChIP-ChIP_HL60_Human1.48351200
36MYCN_18555785_ChIP-Seq_MESCs_Mouse1.48312915
37PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse1.48238884
38IRF8_22096565_ChIP-ChIP_GC-B_Mouse1.48119552
39SMAD_19615063_ChIP-ChIP_OVARY_Human1.44176346
40KLF5_18264089_ChIP-ChIP_MESCs_Mouse1.43768780
41KLF4_18264089_ChIP-ChIP_MESCs_Mouse1.43768780
42KLF2_18264089_ChIP-ChIP_MESCs_Mouse1.43768780
43GABP_19822575_ChIP-Seq_HepG2_Human1.40863250
44POU5F1_16153702_ChIP-ChIP_HESCs_Human1.40817134
45THAP11_20581084_ChIP-Seq_MESCs_Mouse1.40085245
46NELFA_20434984_ChIP-Seq_ESCs_Mouse1.39396467
47ASXL1_24218140_ChIP-Seq_BMDM_Mouse1.39282278
48CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.39033615
49PCGF2_27294783_Chip-Seq_ESCs_Mouse1.38788164
50CREB1_15753290_ChIP-ChIP_HEK293T_Human1.37851362
51TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36754886
52Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.36561404
53SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.35395478
54SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.35395478
55PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.34771768
56EWS_26573619_Chip-Seq_HEK293_Human1.31383356
57IRF8_27001747_Chip-Seq_BMDM_Mouse1.31223890
58VDR_23849224_ChIP-Seq_CD4+_Human1.30322211
59GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.30019924
60SRF_21415370_ChIP-Seq_HL-1_Mouse1.26978432
61NANOG_16153702_ChIP-ChIP_HESCs_Human1.26100007
62NANOG_18555785_ChIP-Seq_MESCs_Mouse1.22783268
63XRN2_22483619_ChIP-Seq_HELA_Human1.21804204
64NOTCH1_21737748_ChIP-Seq_TLL_Human1.20889613
65ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.19685307
66ELF1_17652178_ChIP-ChIP_JURKAT_Human1.19566056
67* ZFX_18555785_ChIP-Seq_MESCs_Mouse1.16724691
68SPI1_22096565_ChIP-ChIP_GC-B_Mouse1.15841567
69* FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.14837868
70SPI1_23547873_ChIP-Seq_NB4_Human1.13868504
71SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.13634791
72E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.12891817
73POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.11966708
74NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.10206337
75KDM5A_27292631_Chip-Seq_BREAST_Human1.08346492
76TFEB_21752829_ChIP-Seq_HELA_Human1.07658514
77CIITA_18437201_ChIP-ChIP_Raji_B_and_iDC_Human1.06561014
78TTF2_22483619_ChIP-Seq_HELA_Human1.06126843
79ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.06026942
80NFE2_27457419_Chip-Seq_LIVER_Mouse1.04441010
81HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.03674931
82TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.02994428
83NANOG_18700969_ChIP-ChIP_MESCs_Mouse1.02706690
84YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.02140155
85DCP1A_22483619_ChIP-Seq_HELA_Human1.01715173
86POU3F2_20337985_ChIP-ChIP_501MEL_Human0.99935289
87CEBPD_23245923_ChIP-Seq_MEFs_Mouse0.97404873
88PADI4_21655091_ChIP-ChIP_MCF-7_Human0.97105758
89BRD4_25478319_ChIP-Seq_HGPS_Human0.97097835
90MYC_18358816_ChIP-ChIP_MESCs_Mouse0.97010785
91SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse0.96373909
92IRF1_21803131_ChIP-Seq_MONOCYTES_Human0.96357308
93SOX2_16153702_ChIP-ChIP_HESCs_Human0.95745925
94MYB_21317192_ChIP-Seq_ERMYB_Mouse0.95648393
95SUZ12_27294783_Chip-Seq_NPCs_Mouse0.95621298
96P300_19829295_ChIP-Seq_ESCs_Human0.94504699
97YY1_21170310_ChIP-Seq_MESCs_Mouse0.94467547
98POU5F1_18358816_ChIP-ChIP_MESCs_Mouse0.93863589
99HOXB4_20404135_ChIP-ChIP_EML_Mouse0.92825775
100CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse0.91864558
101JARID1A_20064375_ChIP-Seq_MESCs_Mouse0.91514363
102SALL4_18804426_ChIP-ChIP_MESCs_Mouse0.90168498
103ETS1_20019798_ChIP-Seq_JURKAT_Human0.90123784
104RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human0.90092712
105SOX17_20123909_ChIP-Seq_XEN_Mouse0.87540674
106IRF1_19129219_ChIP-ChIP_H3396_Human0.86575230
107DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.85740948
108NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.85506386
109WT1_19549856_ChIP-ChIP_CCG9911_Human0.85502998
110ERG_20887958_ChIP-Seq_HPC-7_Mouse0.85350350
111PKCTHETA_26484144_Chip-Seq_BREAST_Human0.84996428
112NANOG_18358816_ChIP-ChIP_MESCs_Mouse0.84724046
113PDX1_19855005_ChIP-ChIP_MIN6_Mouse0.84325459
114CEBPB_23403033_ChIP-Seq_LIVER_Mouse0.84149544
115HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.82888262
116CIITA_25753668_ChIP-Seq_RAJI_Human0.82878460
117E2F1_18555785_Chip-Seq_ESCs_Mouse0.80241518
118AR_21909140_ChIP-Seq_LNCAP_Human0.80206016
119STAT4_19710469_ChIP-ChIP_TH1__Mouse0.80107358
120FUS_26573619_Chip-Seq_HEK293_Human0.79292670
121FOXP3_21729870_ChIP-Seq_TREG_Human0.79233512
122IGF1R_20145208_ChIP-Seq_DFB_Human0.78513759
123PU_27001747_Chip-Seq_BMDM_Mouse0.78197960
124SOX9_22984422_ChIP-ChIP_TESTIS_Rat0.77012970
125NMYC_18555785_Chip-Seq_ESCs_Mouse0.76973010
126CREM_20920259_ChIP-Seq_GC1-SPG_Mouse0.76675056
127TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse0.75491945
128EOMES_20176728_ChIP-ChIP_TSCs_Mouse0.75374702
129EZH2_27294783_Chip-Seq_NPCs_Mouse0.74596002
130SOX2_19030024_ChIP-ChIP_MESCs_Mouse0.73916648
131VDR_22108803_ChIP-Seq_LS180_Human0.73772778
132PCGF2_27294783_Chip-Seq_NPCs_Mouse0.73421935
133E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.73302600
134SOX2_18555785_ChIP-Seq_MESCs_Mouse0.73299516
135SALL4_18804426_ChIP-ChIP_XEN_Mouse0.72752370
136KAP1_22055183_ChIP-Seq_ESCs_Mouse0.71622981
137RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse0.69301512
138NACC1_18358816_ChIP-ChIP_MESCs_Mouse0.68902343
139EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human0.67588317
140CCND1_20090754_ChIP-ChIP_RETINA_Mouse0.65288117

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003941_abnormal_skin_development3.96574926
2MP0008057_abnormal_DNA_replication3.59714429
3MP0003693_abnormal_embryo_hatching2.70935922
4MP0003718_maternal_effect2.55597085
5MP0003195_calcinosis2.40451975
6MP0005451_abnormal_body_composition2.28980556
7MP0008007_abnormal_cellular_replicative2.28938997
8MP0010094_abnormal_chromosome_stability2.16350870
9MP0002796_impaired_skin_barrier2.15216466
10MP0002102_abnormal_ear_morphology2.09155873
11MP0001835_abnormal_antigen_presentation1.96926993
12MP0008058_abnormal_DNA_repair1.96445126
13MP0002148_abnormal_hypersensitivity_rea1.96269021
14MP0003111_abnormal_nucleus_morphology1.93767196
15MP0002938_white_spotting1.93599407
16MP0008877_abnormal_DNA_methylation1.93285022
17MP0004957_abnormal_blastocyst_morpholog1.89307599
18MP0005075_abnormal_melanosome_morpholog1.87643303
19MP0002877_abnormal_melanocyte_morpholog1.86476576
20MP0003123_paternal_imprinting1.86153867
21MP0003077_abnormal_cell_cycle1.84574598
22MP0005408_hypopigmentation1.70464799
23MP0005275_abnormal_skin_tensile1.67653545
24MP0003787_abnormal_imprinting1.65214580
25MP0000015_abnormal_ear_pigmentation1.62163883
26MP0005076_abnormal_cell_differentiation1.59900108
27MP0005501_abnormal_skin_physiology1.56428632
28MP0003136_yellow_coat_color1.49581918
29MP0003121_genomic_imprinting1.47078928
30MP0010352_gastrointestinal_tract_polyps1.44078446
31MP0002060_abnormal_skin_morphology1.42704102
32MP0000516_abnormal_urinary_system1.41797469
33MP0005367_renal/urinary_system_phenotyp1.41797469
34MP0003436_decreased_susceptibility_to1.39991923
35MP0001216_abnormal_epidermal_layer1.37970111
36MP0000566_synostosis1.36895232
37MP0002277_abnormal_respiratory_mucosa1.36537434
38MP0002163_abnormal_gland_morphology1.34881643
39MP0010307_abnormal_tumor_latency1.33906290
40MP0002084_abnormal_developmental_patter1.33741709
41MP0004782_abnormal_surfactant_physiolog1.30845728
42MP0003119_abnormal_digestive_system1.28131681
43* MP0001929_abnormal_gametogenesis1.27832194
44MP0006292_abnormal_olfactory_placode1.26169221
45MP0008789_abnormal_olfactory_epithelium1.25950984
46MP0009672_abnormal_birth_weight1.25578915
47MP0002085_abnormal_embryonic_tissue1.25221568
48MP0002095_abnormal_skin_pigmentation1.24780740
49MP0002098_abnormal_vibrissa_morphology1.24337644
50MP0005171_absent_coat_pigmentation1.24176227
51MP0003786_premature_aging1.22156927
52MP0009333_abnormal_splenocyte_physiolog1.21199279
53MP0003806_abnormal_nucleotide_metabolis1.20012304
54MP0009053_abnormal_anal_canal1.19685454
55MP0002009_preneoplasia1.19192817
56MP0002080_prenatal_lethality1.17090054
57MP0001286_abnormal_eye_development1.16560161
58MP0000350_abnormal_cell_proliferation1.15565263
59MP0005000_abnormal_immune_tolerance1.14504366
60MP0008932_abnormal_embryonic_tissue1.12042834
61MP0003890_abnormal_embryonic-extraembry1.11498631
62MP0003448_altered_tumor_morphology1.10721928
63MP0009785_altered_susceptibility_to1.09931715
64MP0000653_abnormal_sex_gland1.09832636
65MP0003566_abnormal_cell_adhesion1.09619036
66MP0000858_altered_metastatic_potential1.09231697
67MP0001145_abnormal_male_reproductive1.08831255
68MP0001790_abnormal_immune_system1.06465169
69MP0005387_immune_system_phenotype1.06465169
70MP0005174_abnormal_tail_pigmentation1.05607192
71MP0002405_respiratory_system_inflammati1.04871327
72MP0003453_abnormal_keratinocyte_physiol1.04584828
73MP0005395_other_phenotype1.04395776
74MP0001188_hyperpigmentation1.03162258
75MP0002452_abnormal_antigen_presenting1.02869726
76MP0002177_abnormal_outer_ear1.02047219
77MP0003755_abnormal_palate_morphology1.01159923
78MP0004381_abnormal_hair_follicle1.00854628
79MP0003950_abnormal_plasma_membrane1.00156807
80MP0001119_abnormal_female_reproductive0.99772782
81MP0004947_skin_inflammation0.99622209
82MP0002210_abnormal_sex_determination0.99488756
83MP0004197_abnormal_fetal_growth/weight/0.99380249
84MP0010234_abnormal_vibrissa_follicle0.98667107
85MP0008995_early_reproductive_senescence0.97667129
86MP0009703_decreased_birth_body0.97190887
87MP0001672_abnormal_embryogenesis/_devel0.95955833
88MP0005380_embryogenesis_phenotype0.95955833
89MP0002751_abnormal_autonomic_nervous0.95775010
90MP0005394_taste/olfaction_phenotype0.95056428
91MP0005499_abnormal_olfactory_system0.95056428
92MP0002006_tumorigenesis0.94797276
93MP0003646_muscle_fatigue0.94701039
94MP0002419_abnormal_innate_immunity0.94363065
95MP0005248_abnormal_Harderian_gland0.93934840
96MP0002233_abnormal_nose_morphology0.93709633
97MP0004510_myositis0.93092678
98MP0000313_abnormal_cell_death0.90360778
99MP0002132_abnormal_respiratory_system0.89944493
100MP0003385_abnormal_body_wall0.89862803
101MP0005671_abnormal_response_to0.89318869
102MP0000678_abnormal_parathyroid_gland0.87736755
103MP0006035_abnormal_mitochondrial_morpho0.87532073
104MP0001800_abnormal_humoral_immune0.86398798
105MP0002396_abnormal_hematopoietic_system0.86386714
106MP0003984_embryonic_growth_retardation0.85999313
107MP0010678_abnormal_skin_adnexa0.85770227
108MP0005025_abnormal_response_to0.85708457
109MP0001730_embryonic_growth_arrest0.85601603
110MP0010771_integument_phenotype0.85580586
111MP0002086_abnormal_extraembryonic_tissu0.85396485
112MP0002160_abnormal_reproductive_system0.85339082
113MP0000432_abnormal_head_morphology0.85236898
114MP0003943_abnormal_hepatobiliary_system0.84964381
115MP0002088_abnormal_embryonic_growth/wei0.84741060
116MP0001186_pigmentation_phenotype0.84188081
117MP0001191_abnormal_skin_condition0.83635104
118MP0001324_abnormal_eye_pigmentation0.83602011
119MP0002723_abnormal_immune_serum0.83210983
120MP0009697_abnormal_copulation0.82969654
121MP0000762_abnormal_tongue_morphology0.82923719
122MP0003937_abnormal_limbs/digits/tail_de0.82863311
123MP0001819_abnormal_immune_cell0.81738120
124MP0000358_abnormal_cell_content/0.81557922
125MP0005253_abnormal_eye_physiology0.81105591
126MP0003567_abnormal_fetal_cardiomyocyte0.80760947
127MP0003828_pulmonary_edema0.80149564
128MP0000372_irregular_coat_pigmentation0.79927587
129MP0001293_anophthalmia0.79652437
130MP0001346_abnormal_lacrimal_gland0.79507933
131MP0002420_abnormal_adaptive_immunity0.79247991
132MP0002111_abnormal_tail_morphology0.79129331
133MP0000627_abnormal_mammary_gland0.78832950
134MP0006072_abnormal_retinal_apoptosis0.78641566
135MP0002019_abnormal_tumor_incidence0.78249186
136MP0010030_abnormal_orbit_morphology0.77980481
137MP0000647_abnormal_sebaceous_gland0.77891682
138MP0001697_abnormal_embryo_size0.77859388
139MP0001661_extended_life_span0.77303677
140* MP0003698_abnormal_male_reproductive0.76719410
141MP0006054_spinal_hemorrhage0.74576651
142MP0002697_abnormal_eye_size0.73485213
143MP0002090_abnormal_vision0.71776722
144MP0000383_abnormal_hair_follicle0.68037050
145MP0000427_abnormal_hair_cycle0.67702654
146MP0003186_abnormal_redox_activity0.67224420
147MP0005379_endocrine/exocrine_gland_phen0.63373813
148MP0000377_abnormal_hair_follicle0.62870944
149MP0005391_vision/eye_phenotype0.62508778

Predicted human phenotypes

RankGene SetZ-score
1Abnormality of the labia minora (HP:0012880)3.78126386
2Ependymoma (HP:0002888)3.77124758
3Volvulus (HP:0002580)3.40316233
4Colon cancer (HP:0003003)3.34959841
5Chromsome breakage (HP:0040012)3.30973605
6Duodenal stenosis (HP:0100867)3.17034756
7Small intestinal stenosis (HP:0012848)3.17034756
8Chromosomal breakage induced by crosslinking agents (HP:0003221)3.16085973
9Rhabdomyosarcoma (HP:0002859)3.13438436
10Ectopic kidney (HP:0000086)2.99956771
11Lip pit (HP:0100267)2.98369811
12Congenital nonbullous ichthyosiform erythroderma (HP:0007479)2.91185868
13Retrobulbar optic neuritis (HP:0100654)2.88383436
14Optic neuritis (HP:0100653)2.88383436
15Eczematoid dermatitis (HP:0000976)2.85296800
16Birth length less than 3rd percentile (HP:0003561)2.84278660
17Abnormality of the duodenum (HP:0002246)2.81116796
18Recurrent abscess formation (HP:0002722)2.75752111
19Glioma (HP:0009733)2.74903341
20Horseshoe kidney (HP:0000085)2.74063889
21Abnormality of the nasal septum (HP:0000419)2.68771921
22Abnormality of the anterior horn cell (HP:0006802)2.68181008
23Degeneration of anterior horn cells (HP:0002398)2.68181008
24Multiple enchondromatosis (HP:0005701)2.64426525
25Curly hair (HP:0002212)2.62855023
26Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.61265088
27Abnormality of the astrocytes (HP:0100707)2.59979262
28Astrocytoma (HP:0009592)2.59979262
29Spinal cord lesions (HP:0100561)2.50514339
30Syringomyelia (HP:0003396)2.50514339
31Congenital ichthyosiform erythroderma (HP:0007431)2.50317892
32Abnormality of incisor morphology (HP:0011063)2.47643243
33Prostate neoplasm (HP:0100787)2.44961516
34Pancreatic islet-cell hyperplasia (HP:0004510)2.43687486
35Absent forearm bone (HP:0003953)2.43230677
36Aplasia involving forearm bones (HP:0009822)2.43230677
37Abnormality of glycolysis (HP:0004366)2.41688691
38Increased nuchal translucency (HP:0010880)2.39304072
39Recurrent bacterial skin infections (HP:0005406)2.38107355
40Mediastinal lymphadenopathy (HP:0100721)2.36636918
41Abnormality of the carotid arteries (HP:0005344)2.36441513
42Orchitis (HP:0100796)2.35669805
43Parakeratosis (HP:0001036)2.35061678
44Type I transferrin isoform profile (HP:0003642)2.32390093
45Sloping forehead (HP:0000340)2.29924397
4611 pairs of ribs (HP:0000878)2.17161169
47Nephroblastoma (Wilms tumor) (HP:0002667)2.16814928
48Metaphyseal dysplasia (HP:0100255)2.16109822
49Neoplasm of striated muscle (HP:0009728)2.15920988
50Impulsivity (HP:0100710)2.15093805
51Choanal atresia (HP:0000453)2.14517314
52Carpal bone hypoplasia (HP:0001498)2.14400363
53Methylmalonic acidemia (HP:0002912)2.13730579
54Medulloblastoma (HP:0002885)2.13246772
55Abnormality of methionine metabolism (HP:0010901)2.12566087
56Absent thumb (HP:0009777)2.09980061
57Intestinal atresia (HP:0011100)2.09817642
58Stenosis of the external auditory canal (HP:0000402)2.09290083
59Embryonal renal neoplasm (HP:0011794)2.08751682
60Agnosia (HP:0010524)2.07245348
61Spinal muscular atrophy (HP:0007269)2.07000630
62Adrenal hypoplasia (HP:0000835)2.06484265
63Patellar aplasia (HP:0006443)2.05914930
64Triphalangeal thumb (HP:0001199)2.05885129
65Short middle phalanx of the 5th finger (HP:0004220)2.05298023
66Cleft eyelid (HP:0000625)2.02310339
67Erythroderma (HP:0001019)2.01548106
68Meckel diverticulum (HP:0002245)2.00726276
69Neoplasm of the colon (HP:0100273)1.99207926
70Reticulocytopenia (HP:0001896)1.98933311
71Abnormality of the preputium (HP:0100587)1.98539160
72Increased serum pyruvate (HP:0003542)1.98519161
73Embryonal neoplasm (HP:0002898)1.97821673
74Deep philtrum (HP:0002002)1.95318460
75Oligodactyly (hands) (HP:0001180)1.93219392
76Aplasia/Hypoplasia of the patella (HP:0006498)1.92805950
77Abnormality of DNA repair (HP:0003254)1.92682159
78Neoplasm of the adrenal cortex (HP:0100641)1.91806999
79Natal tooth (HP:0000695)1.89954384
80Abnormality of the ileum (HP:0001549)1.89872936
81Neoplasm of the adrenal gland (HP:0100631)1.89776174
82Hyperglycinemia (HP:0002154)1.89425411
83Cafe-au-lait spot (HP:0000957)1.88092631
84Myositis (HP:0100614)1.87519870
85Obstructive lung disease (HP:0006536)1.87183183
86Chronic obstructive pulmonary disease (HP:0006510)1.87183183
87Breast hypoplasia (HP:0003187)1.87016647
88Abnormality of aspartate family amino acid metabolism (HP:0010899)1.85831858
89High anterior hairline (HP:0009890)1.85529334
90Abnormality of chromosome stability (HP:0003220)1.84656306
91Pendular nystagmus (HP:0012043)1.84529085
92Facial cleft (HP:0002006)1.83650146
93Abnormal isoelectric focusing of serum transferrin (HP:0003160)1.81544519
94Abnormal protein N-linked glycosylation (HP:0012347)1.81544519
95Abnormal protein glycosylation (HP:0012346)1.81544519
96Abnormal glycosylation (HP:0012345)1.81544519
97Abnormality of the phalanges of the 5th finger (HP:0004213)1.80475265
98Abnormality of the incisor (HP:0000676)1.79632261
99Abnormal auditory evoked potentials (HP:0006958)1.79569480
100Absent eyebrow (HP:0002223)1.78664662
101Breast carcinoma (HP:0003002)1.78503489
102Increased IgM level (HP:0003496)1.78191206
103Gangrene (HP:0100758)1.76647898
104Aplasia/Hypoplasia of the phalanges of the 5th finger (HP:0009376)1.76562296
105Absent frontal sinuses (HP:0002688)1.74946970
106Small hand (HP:0200055)1.73889607
107Keratoconjunctivitis sicca (HP:0001097)1.73880977
108Alveolar cell carcinoma (HP:0006519)1.73847461
109Asymmetry of the thorax (HP:0001555)1.73601622
110Homocystinuria (HP:0002156)1.72321604
111Abnormality of homocysteine metabolism (HP:0010919)1.72321604
112Acute myeloid leukemia (HP:0004808)1.72089817
113Abnormality of the renal collecting system (HP:0004742)1.71785215
114Abnormal hair whorl (HP:0010721)1.71056579
115Ovarian neoplasm (HP:0100615)1.70221534
116Progressive inability to walk (HP:0002505)1.69877809
117Distal lower limb muscle weakness (HP:0009053)1.69825807
118Aplasia/Hypoplasia of the uvula (HP:0010293)1.69234003
119Prominent metopic ridge (HP:0005487)1.69054756
120Thick nail (HP:0001805)1.68186099
121Abnormality of the fingertips (HP:0001211)1.67896970
122Gonadotropin excess (HP:0000837)1.67832751
123Abnormality of serum amino acid levels (HP:0003112)1.67663297
124Keratoconjunctivitis (HP:0001096)1.67037538
125Aplasia/Hypoplasia of the frontal sinuses (HP:0009119)1.66616234
126Abnormal lung lobation (HP:0002101)1.66576278
127Proximal placement of thumb (HP:0009623)1.66154976
128Hypoplastic pelvis (HP:0008839)1.65532836
129Short thumb (HP:0009778)1.65489202
130Dyschromatopsia (HP:0007641)1.65435552
131Increased IgE level (HP:0003212)1.65111188
132Neoplasm of the tracheobronchial system (HP:0100552)1.64169591
133Abnormality of the metopic suture (HP:0005556)1.63445501
134Palmar hyperkeratosis (HP:0010765)1.63440312
135Abnormality of the parathyroid morphology (HP:0011766)1.63161535
136Popliteal pterygium (HP:0009756)1.63092696
137Abnormality of the middle phalanx of the 5th finger (HP:0004219)1.62525421
138Abnormality of the pons (HP:0007361)1.61712575
139Renal agenesis (HP:0000104)1.61097991
140Clubbing of toes (HP:0100760)1.61058609
141Myelodysplasia (HP:0002863)1.60496049
142Cystic hygroma (HP:0000476)1.60205185
143Astigmatism (HP:0000483)1.59914131
144Aseptic necrosis (HP:0010885)1.59521456
145Bilateral sensorineural hearing impairment (HP:0008619)1.59081426
146Abnormal gallbladder physiology (HP:0012438)1.58879162
147Cholecystitis (HP:0001082)1.58879162
148Squamous cell carcinoma (HP:0002860)1.58472196
149Plantar hyperkeratosis (HP:0007556)1.58072147
150Long clavicles (HP:0000890)1.57891791
151Supernumerary spleens (HP:0009799)1.57878500
152Palmoplantar hyperkeratosis (HP:0000972)1.57617829
153Neoplasm of the oral cavity (HP:0100649)1.57351689
154Irregular epiphyses (HP:0010582)1.56935307
155Abnormality of the frontal sinuses (HP:0002687)1.56772917
156Patent foramen ovale (HP:0001655)1.56501024
157Arteriovenous malformation (HP:0100026)1.56436313
158Recurrent pneumonia (HP:0006532)1.56146290
159Duplicated collecting system (HP:0000081)1.55634442
160Rhinitis (HP:0012384)1.55164001
161Freckling (HP:0001480)1.54998849
162Aplasia/Hypoplasia of the middle phalanx of the 5th finger (HP:0009161)1.54993119
163Abnormal respiratory motile cilium physiology (HP:0012261)1.54719601
164Aplasia/Hypoplasia of the fovea (HP:0008060)1.54485023
165Hypoplasia of the fovea (HP:0007750)1.54485023
166Dynein arm defect of respiratory motile cilia (HP:0012255)1.53408368
167Absent/shortened dynein arms (HP:0200106)1.53408368
168Deviation of the thumb (HP:0009603)1.52511349
169Abnormality of endocrine pancreas physiology (HP:0012093)1.52486147
170Absent radius (HP:0003974)1.50434331
171Abnormal respiratory motile cilium morphology (HP:0005938)1.49745804
172Abnormal respiratory epithelium morphology (HP:0012253)1.49745804
173Epiphyseal dysplasia (HP:0002656)1.49638707
174Osteomalacia (HP:0002749)1.48562397
175Capillary hemangiomas (HP:0005306)1.47283505
176Abnormality of nail color (HP:0100643)1.47115442
177Aplasia/Hypoplasia of the sternum (HP:0006714)1.46612410

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BUB13.98903573
2EIF2AK33.44860368
3MAP3K143.39592898
4BMPR22.86375204
5LATS12.80530342
6TRIM282.79148393
7STK38L2.63651310
8ZAK2.63165532
9IRAK32.61280616
10PRPF4B2.46604547
11BMPR1B2.45194908
12CDK122.37627469
13ERBB32.26046227
14PLK42.25256871
15NEK12.19803500
16IRAK42.15363169
17MST42.15051928
18SRPK12.07024586
19NUAK12.02341169
20VRK21.99988746
21STK31.97386230
22STK241.92080269
23WNK31.91317801
24TAF11.85144894
25PBK1.64967242
26PIM21.58526698
27BRSK21.57513716
28IKBKB1.52902154
29CHUK1.52763722
30MKNK11.47279234
31TTK1.46082268
32PLK31.45296218
33FRK1.45139230
34CDC71.44661521
35TRPM71.39203373
36MKNK21.38223588
37RPS6KA41.37111948
38YES11.34524695
39MARK31.30429309
40PIM11.30133287
41EIF2AK21.28499480
42BRD41.27615240
43TXK1.26958459
44AKT31.24020505
45JAK31.23911843
46TNIK1.23543367
47SIK31.21471784
48NLK1.18383161
49MAP3K31.18184469
50TESK11.16441406
51EPHA21.15590457
52BRSK11.14825286
53PRKD31.10822070
54CDK81.03100872
55STK101.02634829
56NEK91.02162668
57CDK71.00345992
58LATS21.00286788
59ATR0.99110728
60CLK10.98621899
61CDK60.96673121
62FGFR10.93619661
63ATM0.92862075
64PLK10.90970958
65CHEK20.90029504
66RIPK40.88491190
67PLK20.85892898
68CDK30.85038282
69PDK20.85022652
70NEK20.84750489
71MAP3K50.82473479
72CHEK10.81035086
73TYK20.80912265
74ACVR1B0.77961493
75CSNK1G10.77637231
76ABL20.77463955
77EIF2AK10.71352602
78FGFR20.70165423
79BCR0.68468025
80BLK0.68355520
81STK40.67507961
82TSSK60.65327540
83MELK0.64158867
84SGK20.63741486
85STK390.63720490
86AURKB0.62289684
87WEE10.61728307
88NME10.61315444
89FER0.61074326
90TEC0.60402522
91MAPKAPK20.59085539
92VRK10.58856888
93CDK10.57545513
94ALK0.57165564
95TGFBR10.55603727
96PRKCI0.55006499
97MAP3K40.54733074
98FLT30.53462235
99TIE10.53004022
100PASK0.52684017
101IKBKE0.52440418
102NME20.51985021
103BMX0.51123248
104TLK10.50960956
105OBSCN0.50894108
106RPS6KC10.50715767
107RPS6KL10.50715767
108CDK40.50039857
109MET0.49972723
110CSNK2A10.49528033
111CSNK1A1L0.49345964
112MAP3K100.49232965
113RPS6KB10.49079632
114NEK60.48559758
115RPS6KA60.48430935
116IRAK10.48116660
117CDK20.47371701
118AKT10.47048557
119AURKA0.46147903
120CDK90.45963111
121STK160.45816832
122PNCK0.42471415
123CSNK1E0.41730251
124PAK40.41547400
125MAP3K60.41527405
126MAP3K80.41342259
127PRKDC0.40632058
128TAOK20.40338603
129OXSR10.39782785
130GRK70.39395917
131ABL10.38018905
132CSNK2A20.37644604
133CSNK1G30.37307005
134BRAF0.36808207
135ERBB40.36427997
136ADRBK20.36386829
137FGR0.33207446
138GRK10.31331351
139CAMK1G0.30918235
140CDK190.30628911
141CCNB10.29259228
142MAP4K20.25893627
143TGFBR20.25269767
144SMG10.25079826
145CSNK1G20.24814486
146CSNK1D0.22388647

Predicted pathways (KEGG)

RankGene SetZ-score
1Graft-versus-host disease_Homo sapiens_hsa053322.15484866
2* Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.05772420
3Homologous recombination_Homo sapiens_hsa034402.00976528
4DNA replication_Homo sapiens_hsa030301.99683977
5Cytosolic DNA-sensing pathway_Homo sapiens_hsa046231.98256229
6RNA polymerase_Homo sapiens_hsa030201.92564344
7Cysteine and methionine metabolism_Homo sapiens_hsa002701.91195786
8Mismatch repair_Homo sapiens_hsa034301.90423553
9Basal transcription factors_Homo sapiens_hsa030221.88496322
10Steroid biosynthesis_Homo sapiens_hsa001001.87971018
11RNA transport_Homo sapiens_hsa030131.81381845
12Allograft rejection_Homo sapiens_hsa053301.80260504
13Propanoate metabolism_Homo sapiens_hsa006401.79632023
14Fanconi anemia pathway_Homo sapiens_hsa034601.78130141
15Base excision repair_Homo sapiens_hsa034101.77443388
16Cell cycle_Homo sapiens_hsa041101.75958723
17Proteasome_Homo sapiens_hsa030501.74214073
18Selenocompound metabolism_Homo sapiens_hsa004501.74153425
19Legionellosis_Homo sapiens_hsa051341.70032005
20NOD-like receptor signaling pathway_Homo sapiens_hsa046211.68472344
21* NF-kappa B signaling pathway_Homo sapiens_hsa040641.66196162
22Spliceosome_Homo sapiens_hsa030401.64799678
23Vitamin B6 metabolism_Homo sapiens_hsa007501.62043892
24mRNA surveillance pathway_Homo sapiens_hsa030151.61366122
25RNA degradation_Homo sapiens_hsa030181.60512173
26Leishmaniasis_Homo sapiens_hsa051401.55930523
27* Herpes simplex infection_Homo sapiens_hsa051681.50729254
28One carbon pool by folate_Homo sapiens_hsa006701.50212399
29Nucleotide excision repair_Homo sapiens_hsa034201.49745716
30p53 signaling pathway_Homo sapiens_hsa041151.44467579
31Oocyte meiosis_Homo sapiens_hsa041141.38547477
32Fatty acid elongation_Homo sapiens_hsa000621.35158345
33Terpenoid backbone biosynthesis_Homo sapiens_hsa009001.34577097
34Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.34570035
35Citrate cycle (TCA cycle)_Homo sapiens_hsa000201.34500541
36Inflammatory bowel disease (IBD)_Homo sapiens_hsa053211.31748962
37* Measles_Homo sapiens_hsa051621.27483204
38Toll-like receptor signaling pathway_Homo sapiens_hsa046201.27200733
39Type I diabetes mellitus_Homo sapiens_hsa049401.25401875
40Non-homologous end-joining_Homo sapiens_hsa034501.25326597
412-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.23003408
42Asthma_Homo sapiens_hsa053101.22904105
43Autoimmune thyroid disease_Homo sapiens_hsa053201.20352397
44* Epstein-Barr virus infection_Homo sapiens_hsa051691.16530957
45Influenza A_Homo sapiens_hsa051641.14274437
46Valine, leucine and isoleucine degradation_Homo sapiens_hsa002801.14191507
47Pyruvate metabolism_Homo sapiens_hsa006201.11943022
48Protein export_Homo sapiens_hsa030601.11006133
49Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.09470167
50Antigen processing and presentation_Homo sapiens_hsa046121.08700209
51Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.08597715
52TNF signaling pathway_Homo sapiens_hsa046681.07239230
53Rheumatoid arthritis_Homo sapiens_hsa053231.07131358
54Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.04116051
55HTLV-I infection_Homo sapiens_hsa051661.03628303
56TGF-beta signaling pathway_Homo sapiens_hsa043501.03303053
57Intestinal immune network for IgA production_Homo sapiens_hsa046721.01893542
58Tuberculosis_Homo sapiens_hsa051521.01388303
59Arachidonic acid metabolism_Homo sapiens_hsa005900.99922632
60Pyrimidine metabolism_Homo sapiens_hsa002400.99606060
61Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.99037976
62Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.98669346
63Biosynthesis of amino acids_Homo sapiens_hsa012300.98606189
64Apoptosis_Homo sapiens_hsa042100.98025969
65Osteoclast differentiation_Homo sapiens_hsa043800.97904417
66Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.97311878
67MicroRNAs in cancer_Homo sapiens_hsa052060.96382901
68Ubiquitin mediated proteolysis_Homo sapiens_hsa041200.95084268
69RIG-I-like receptor signaling pathway_Homo sapiens_hsa046220.94694538
70Pertussis_Homo sapiens_hsa051330.94532462
71Hippo signaling pathway_Homo sapiens_hsa043900.94440393
72Prostate cancer_Homo sapiens_hsa052150.92162891
73Toxoplasmosis_Homo sapiens_hsa051450.91312919
74* Adherens junction_Homo sapiens_hsa045200.90612287
75Ribosome_Homo sapiens_hsa030100.90044521
76Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.89978886
77Carbon metabolism_Homo sapiens_hsa012000.89248045
78Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.89209643
79Hematopoietic cell lineage_Homo sapiens_hsa046400.88628302
80Jak-STAT signaling pathway_Homo sapiens_hsa046300.85772476
81Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.84384778
82Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045500.84080425
83Hepatitis B_Homo sapiens_hsa051610.84053462
84Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.82995461
85N-Glycan biosynthesis_Homo sapiens_hsa005100.81197886
86Transcriptional misregulation in cancer_Homo sapiens_hsa052020.80226429
87Sphingolipid metabolism_Homo sapiens_hsa006000.80005737
88Progesterone-mediated oocyte maturation_Homo sapiens_hsa049140.79130939
89Lysine degradation_Homo sapiens_hsa003100.77204038
90Basal cell carcinoma_Homo sapiens_hsa052170.77177024
91Malaria_Homo sapiens_hsa051440.76560460
92Salmonella infection_Homo sapiens_hsa051320.75865875
93Viral carcinogenesis_Homo sapiens_hsa052030.72335858
94Phagosome_Homo sapiens_hsa041450.72224802
95Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006010.71990064
96Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.71843090
97African trypanosomiasis_Homo sapiens_hsa051430.70267300
98Small cell lung cancer_Homo sapiens_hsa052220.69281627
99B cell receptor signaling pathway_Homo sapiens_hsa046620.66103024
100Shigellosis_Homo sapiens_hsa051310.65733351
101T cell receptor signaling pathway_Homo sapiens_hsa046600.63946868
102Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.62092559
103Natural killer cell mediated cytotoxicity_Homo sapiens_hsa046500.61066955
104Chemokine signaling pathway_Homo sapiens_hsa040620.60710370
105Chagas disease (American trypanosomiasis)_Homo sapiens_hsa051420.60604802
106Hepatitis C_Homo sapiens_hsa051600.58134009
107Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.57190048
108Viral myocarditis_Homo sapiens_hsa054160.57075756
109Thyroid cancer_Homo sapiens_hsa052160.56942997
110Fatty acid metabolism_Homo sapiens_hsa012120.55647589
111Butanoate metabolism_Homo sapiens_hsa006500.55431508
112Glutathione metabolism_Homo sapiens_hsa004800.54679332
113FoxO signaling pathway_Homo sapiens_hsa040680.54578965
114Acute myeloid leukemia_Homo sapiens_hsa052210.54424077
115Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.53846468
116AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa049330.53100228
117Endometrial cancer_Homo sapiens_hsa052130.53027741
118* Wnt signaling pathway_Homo sapiens_hsa043100.52489862
119Melanoma_Homo sapiens_hsa052180.51905456
120Hedgehog signaling pathway_Homo sapiens_hsa043400.51443314
121Linoleic acid metabolism_Homo sapiens_hsa005910.50692163
122Chronic myeloid leukemia_Homo sapiens_hsa052200.50314954
123Primary immunodeficiency_Homo sapiens_hsa053400.49506177
124Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.48684646
125Purine metabolism_Homo sapiens_hsa002300.48080022
126Pathways in cancer_Homo sapiens_hsa052000.47093495
127Metabolic pathways_Homo sapiens_hsa011000.46829284
128Epithelial cell signaling in Helicobacter pylori infection_Homo sapiens_hsa051200.45872317
129Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009700.45521275
130Leukocyte transendothelial migration_Homo sapiens_hsa046700.45502807
131Proteoglycans in cancer_Homo sapiens_hsa052050.43967896
132SNARE interactions in vesicular transport_Homo sapiens_hsa041300.43766166
133Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.42022040
134Prolactin signaling pathway_Homo sapiens_hsa049170.41246493
135Phototransduction_Homo sapiens_hsa047440.39056727
136Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.37752625
137Huntingtons disease_Homo sapiens_hsa050160.33324840
138Pentose and glucuronate interconversions_Homo sapiens_hsa000400.29581229
139Pentose phosphate pathway_Homo sapiens_hsa000300.26600398
140Nitrogen metabolism_Homo sapiens_hsa009100.25799345
141Parkinsons disease_Homo sapiens_hsa050120.25783502
142Colorectal cancer_Homo sapiens_hsa052100.25399219
143beta-Alanine metabolism_Homo sapiens_hsa004100.25144274
144Ether lipid metabolism_Homo sapiens_hsa005650.23431815
145Vitamin digestion and absorption_Homo sapiens_hsa049770.23257820
146Maturity onset diabetes of the young_Homo sapiens_hsa049500.22604419
147Sulfur metabolism_Homo sapiens_hsa009200.16735866
148Peroxisome_Homo sapiens_hsa041460.16524751
149Folate biosynthesis_Homo sapiens_hsa007900.16165324
150Retinol metabolism_Homo sapiens_hsa008300.14667149
151Fatty acid degradation_Homo sapiens_hsa000710.13300513
152Caffeine metabolism_Homo sapiens_hsa002320.13087566
153Regulation of autophagy_Homo sapiens_hsa041400.12594294
154Arginine and proline metabolism_Homo sapiens_hsa003300.09200479
155Oxidative phosphorylation_Homo sapiens_hsa001900.08478352
156* Tight junction_Homo sapiens_hsa045300.07979182
157Drug metabolism - other enzymes_Homo sapiens_hsa009830.07902016

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