Rank | Gene Set | Z-score |
---|---|---|
1 | collagen fibril organization (GO:0030199) | 6.13046299 |
2 | protein heterotrimerization (GO:0070208) | 5.70622387 |
3 | chondrocyte proliferation (GO:0035988) | 5.64015694 |
4 | cartilage development involved in endochondral bone morphogenesis (GO:0060351) | 5.34979722 |
5 | chondrocyte development (GO:0002063) | 4.52325472 |
6 | endodermal cell differentiation (GO:0035987) | 4.51278827 |
7 | vascular endothelial growth factor signaling pathway (GO:0038084) | 4.51240213 |
8 | skin morphogenesis (GO:0043589) | 4.46184945 |
9 | collagen metabolic process (GO:0032963) | 4.34625287 |
10 | plasma membrane repair (GO:0001778) | 4.34281871 |
11 | collagen catabolic process (GO:0030574) | 4.34131746 |
12 | cardiac myofibril assembly (GO:0055003) | 4.31515070 |
13 | multicellular organismal macromolecule metabolic process (GO:0044259) | 4.13892510 |
14 | positive regulation of endothelial cell apoptotic process (GO:2000353) | 4.13118795 |
15 | multicellular organismal catabolic process (GO:0044243) | 3.98079864 |
16 | bone trabecula formation (GO:0060346) | 3.91839843 |
17 | multicellular organismal metabolic process (GO:0044236) | 3.89091131 |
18 | glomerular filtration (GO:0003094) | 3.81334219 |
19 | barbed-end actin filament capping (GO:0051016) | 3.76266612 |
20 | extracellular matrix disassembly (GO:0022617) | 3.72392785 |
21 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.68970459 |
22 | cell-substrate adherens junction assembly (GO:0007045) | 3.68125645 |
23 | focal adhesion assembly (GO:0048041) | 3.68125645 |
24 | sequestering of extracellular ligand from receptor (GO:0035581) | 3.68076999 |
25 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 3.63290288 |
26 | basement membrane organization (GO:0071711) | 3.61363579 |
27 | negative regulation of homotypic cell-cell adhesion (GO:0034111) | 3.59154112 |
28 | cell adhesion mediated by integrin (GO:0033627) | 3.56020445 |
29 | glomerular basement membrane development (GO:0032836) | 3.53241135 |
30 | wound healing, spreading of epidermal cells (GO:0035313) | 3.46781866 |
31 | renal filtration (GO:0097205) | 3.45466602 |
32 | keratan sulfate catabolic process (GO:0042340) | 3.41191277 |
33 | cell aggregation (GO:0098743) | 3.36998897 |
34 | cartilage condensation (GO:0001502) | 3.36998897 |
35 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.36615583 |
36 | axon extension involved in axon guidance (GO:0048846) | 3.36615583 |
37 | positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S tr | 3.36479323 |
38 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.34925281 |
39 | regulation of plasminogen activation (GO:0010755) | 3.28027459 |
40 | negative regulation of fatty acid transport (GO:2000192) | 3.27937569 |
41 | myofibril assembly (GO:0030239) | 3.25453373 |
42 | negative regulation of chondrocyte differentiation (GO:0032331) | 3.22663675 |
43 | endothelial cell morphogenesis (GO:0001886) | 3.21723607 |
44 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.20547613 |
45 | positive regulation of blood vessel endothelial cell migration (GO:0043536) | 3.19923134 |
46 | melanin biosynthetic process (GO:0042438) | 3.19398289 |
47 | metanephric mesenchyme development (GO:0072075) | 3.17268501 |
48 | positive regulation of extracellular matrix organization (GO:1903055) | 3.16556485 |
49 | replacement ossification (GO:0036075) | 3.15758107 |
50 | endochondral ossification (GO:0001958) | 3.15758107 |
51 | semaphorin-plexin signaling pathway (GO:0071526) | 3.15304786 |
52 | apoptotic cell clearance (GO:0043277) | 3.14947972 |
53 | Golgi transport vesicle coating (GO:0048200) | 3.13486604 |
54 | COPI coating of Golgi vesicle (GO:0048205) | 3.13486604 |
55 | muscle cell migration (GO:0014812) | 3.12605448 |
56 | protein retention in ER lumen (GO:0006621) | 3.11756691 |
57 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 3.09981356 |
58 | protein localization to endosome (GO:0036010) | 3.08424906 |
59 | negative regulation of smooth muscle cell migration (GO:0014912) | 3.07545314 |
60 | extracellular matrix organization (GO:0030198) | 3.07324888 |
61 | substrate-dependent cell migration (GO:0006929) | 3.07238913 |
62 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition | 3.06843128 |
63 | adhesion of symbiont to host cell (GO:0044650) | 3.06770169 |
64 | virion attachment to host cell (GO:0019062) | 3.06770169 |
65 | cell-substrate junction assembly (GO:0007044) | 3.06125983 |
66 | extracellular structure organization (GO:0043062) | 3.05941524 |
67 | positive regulation of astrocyte differentiation (GO:0048711) | 3.05453769 |
68 | kidney mesenchyme development (GO:0072074) | 3.04842758 |
69 | * chondroitin sulfate biosynthetic process (GO:0030206) | 3.02657999 |
70 | cell proliferation involved in metanephros development (GO:0072203) | 3.02465401 |
71 | cell migration involved in heart development (GO:0060973) | 3.02026246 |
72 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.01837082 |
73 | actin filament depolymerization (GO:0030042) | 2.98704050 |
74 | negative regulation of cartilage development (GO:0061037) | 2.96527527 |
75 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.96366395 |
76 | vascular endothelial growth factor receptor signaling pathway (GO:0048010) | 2.94161601 |
77 | * dermatan sulfate biosynthetic process (GO:0030208) | 2.92636626 |
78 | adhesion of symbiont to host (GO:0044406) | 2.92368602 |
79 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 2.92026500 |
80 | glomerular visceral epithelial cell development (GO:0072015) | 2.89526938 |
81 | extracellular matrix assembly (GO:0085029) | 2.87451618 |
82 | positive regulation of cartilage development (GO:0061036) | 2.87073499 |
83 | stress fiber assembly (GO:0043149) | 2.87040044 |
84 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.86047562 |
85 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.85789680 |
86 | regulation of chondrocyte differentiation (GO:0032330) | 2.84998962 |
87 | hypotonic response (GO:0006971) | 2.84010325 |
88 | positive regulation of osteoblast proliferation (GO:0033690) | 2.83500284 |
89 | regulation of cartilage development (GO:0061035) | 2.81826739 |
90 | melanin metabolic process (GO:0006582) | 2.81289648 |
91 | fibril organization (GO:0097435) | 2.78902619 |
92 | negative regulation of adherens junction organization (GO:1903392) | 2.74537057 |
93 | negative regulation of focal adhesion assembly (GO:0051895) | 2.74537057 |
94 | negative regulation of cell junction assembly (GO:1901889) | 2.74537057 |
95 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.73735654 |
96 | cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.73351690 |
97 | peptidyl-proline hydroxylation (GO:0019511) | 2.73136542 |
98 | * dermatan sulfate metabolic process (GO:0030205) | 2.73011078 |
99 | cellular response to vitamin (GO:0071295) | 2.72312162 |
100 | trabecula formation (GO:0060343) | 2.72046812 |
101 | regulation of tight junction assembly (GO:2000810) | 2.70140887 |
102 | cartilage development (GO:0051216) | 2.69619095 |
103 | positive regulation of chondrocyte differentiation (GO:0032332) | 2.68584608 |
104 | positive regulation of axon extension (GO:0045773) | 2.68183639 |
105 | epithelial cell-cell adhesion (GO:0090136) | 2.67668448 |
106 | hemidesmosome assembly (GO:0031581) | 2.67631919 |
107 | extracellular fibril organization (GO:0043206) | 2.66483944 |
108 | type B pancreatic cell proliferation (GO:0044342) | 2.65540701 |
109 | embryonic viscerocranium morphogenesis (GO:0048703) | 2.65111175 |
110 | regulation of early endosome to late endosome transport (GO:2000641) | 2.64544052 |
111 | cell proliferation involved in kidney development (GO:0072111) | 2.64494590 |
112 | positive regulation of epithelial to mesenchymal transition (GO:0010718) | 2.64267763 |
113 | atrioventricular valve morphogenesis (GO:0003181) | 2.63563468 |
114 | protein localization to cell surface (GO:0034394) | 2.62706320 |
115 | wound healing, spreading of cells (GO:0044319) | 2.61451251 |
116 | positive regulation of fibroblast migration (GO:0010763) | 2.60693565 |
117 | metanephric nephron tubule development (GO:0072234) | 2.59675236 |
118 | metanephric tubule development (GO:0072170) | 2.59675236 |
119 | positive regulation of stem cell differentiation (GO:2000738) | 2.59374101 |
120 | response to fluid shear stress (GO:0034405) | 2.59254318 |
121 | cortical actin cytoskeleton organization (GO:0030866) | 2.58836084 |
122 | mesenchymal-epithelial cell signaling (GO:0060638) | 2.58826547 |
123 | craniofacial suture morphogenesis (GO:0097094) | 2.57564979 |
124 | regulation of axon extension involved in axon guidance (GO:0048841) | 2.57388095 |
125 | heparan sulfate proteoglycan biosynthetic process (GO:0015012) | 2.56494057 |
126 | adherens junction assembly (GO:0034333) | 2.56149224 |
127 | cortical cytoskeleton organization (GO:0030865) | 2.56001647 |
128 | paraxial mesoderm development (GO:0048339) | 2.55642021 |
129 | endocardial cushion morphogenesis (GO:0003203) | 2.53230683 |
130 | protein hydroxylation (GO:0018126) | 2.53227286 |
131 | endocardial cushion development (GO:0003197) | 2.53063266 |
132 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.52566518 |
133 | notochord development (GO:0030903) | 2.52380723 |
134 | tooth mineralization (GO:0034505) | 2.51215158 |
135 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.50758150 |
136 | cellular response to amino acid stimulus (GO:0071230) | 2.50682505 |
137 | coronary vasculature morphogenesis (GO:0060977) | 2.50410496 |
138 | cell volume homeostasis (GO:0006884) | 2.49618358 |
139 | negative regulation of catenin import into nucleus (GO:0035414) | 2.47546149 |
140 | sarcomere organization (GO:0045214) | 2.47407718 |
141 | heart morphogenesis (GO:0003007) | 2.47352456 |
142 | regulation of integrin-mediated signaling pathway (GO:2001044) | 2.47154674 |
143 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.46623405 |
144 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan (GO:0019800) | 2.44899380 |
145 | endothelial cell chemotaxis (GO:0035767) | 2.43950921 |
146 | cell-matrix adhesion (GO:0007160) | 2.43687569 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 5.45297426 |
2 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.41628728 |
3 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 3.63111826 |
4 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 3.16948044 |
5 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.47018956 |
6 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 2.41163986 |
7 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 2.38287930 |
8 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 2.33217571 |
9 | AR_21572438_ChIP-Seq_LNCaP_Human | 2.22089638 |
10 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.22072162 |
11 | * RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 2.16727253 |
12 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 2.15588757 |
13 | RNF2_18974828_ChIP-Seq_MESCs_Mouse | 2.15167669 |
14 | EZH2_18974828_ChIP-Seq_MESCs_Mouse | 2.15167669 |
15 | SUZ12_18555785_ChIP-Seq_MESCs_Mouse | 2.13224338 |
16 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 2.09098352 |
17 | CJUN_26792858_Chip-Seq_BT549_Human | 2.07707724 |
18 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 2.06077623 |
19 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 2.05564130 |
20 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 2.04708171 |
21 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 2.01535482 |
22 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 1.89956177 |
23 | SUZ12_18974828_ChIP-Seq_MESCs_Mouse | 1.89285791 |
24 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.86517627 |
25 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.81761030 |
26 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.78279726 |
27 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.74393572 |
28 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.73499187 |
29 | JARID2_20075857_ChIP-Seq_MESCs_Mouse | 1.73374642 |
30 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.72855367 |
31 | ZNF263_19887448_ChIP-Seq_K562_Human | 1.68390999 |
32 | EZH2_27304074_Chip-Seq_ESCs_Mouse | 1.68064886 |
33 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.66622565 |
34 | JARID2_20064375_ChIP-Seq_MESCs_Mouse | 1.63974378 |
35 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.61270584 |
36 | MTF2_20144788_ChIP-Seq_MESCs_Mouse | 1.60187237 |
37 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 1.56737506 |
38 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.56542475 |
39 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 1.56449377 |
40 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 1.56449377 |
41 | RNF2_16625203_ChIP-ChIP_MESCs_Mouse | 1.55348528 |
42 | PHC1_16625203_ChIP-ChIP_MESCs_Mouse | 1.52591524 |
43 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.49649307 |
44 | SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.49227681 |
45 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.48738471 |
46 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.47701659 |
47 | TP53_16413492_ChIP-PET_HCT116_Human | 1.47307465 |
48 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.45956983 |
49 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.45956983 |
50 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.45480193 |
51 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.45256226 |
52 | TP53_20018659_ChIP-ChIP_R1E_Mouse | 1.44548030 |
53 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.44240134 |
54 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.42600814 |
55 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.42447896 |
56 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.41908660 |
57 | RNF2_27304074_Chip-Seq_ESCs_Mouse | 1.40742520 |
58 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.39849080 |
59 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.39682722 |
60 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.38775112 |
61 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.37344908 |
62 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.35351659 |
63 | EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 1.34459152 |
64 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.33665662 |
65 | SMC1_22415368_ChIP-Seq_MEFs_Mouse | 1.32897034 |
66 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.32794510 |
67 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.32444454 |
68 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 1.31070018 |
69 | * KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.29396232 |
70 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.29165966 |
71 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.26540444 |
72 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.22602955 |
73 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.22392342 |
74 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.22012628 |
75 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.20731991 |
76 | WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.20273537 |
77 | ERG_21242973_ChIP-ChIP_JURKAT_Human | 1.19904824 |
78 | ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.19661262 |
79 | * JUN_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.18914946 |
80 | TET1_21490601_ChIP-Seq_MESCs_Mouse | 1.18690946 |
81 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 1.18497705 |
82 | SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.18321882 |
83 | SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.18321882 |
84 | MEF2A_21415370_ChIP-Seq_HL-1_Mouse | 1.17631082 |
85 | * JUND_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.17165344 |
86 | MYCN_19997598_ChIP-ChIP_NEUROBLASTOMA_Human | 1.15905845 |
87 | SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.15682606 |
88 | EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.15457726 |
89 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 1.15317295 |
90 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.15002937 |
91 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 1.12829126 |
92 | TRIM28_17542650_ChIP-ChIP_NTERA2_Human | 1.10460796 |
93 | * TP53_22127205_ChIP-Seq_IMR90_Human | 1.10060471 |
94 | SA1_22415368_ChIP-Seq_MEFs_Mouse | 1.10031443 |
95 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.09764698 |
96 | ATF3_27146783_Chip-Seq_COLON_Human | 1.09557040 |
97 | TP53_23651856_ChIP-Seq_MEFs_Mouse | 1.09207251 |
98 | * KLF4_18358816_ChIP-ChIP_MESCs_Mouse | 1.09166271 |
99 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 1.08485407 |
100 | ZFP281_18757296_ChIP-ChIP_E14_Mouse | 1.08138929 |
101 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.08108625 |
102 | CTCF_27219007_Chip-Seq_ERYTHROID_Human | 1.07277387 |
103 | SUZ12_27294783_Chip-Seq_ESCs_Mouse | 1.06826133 |
104 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.06700993 |
105 | RING1B_27294783_Chip-Seq_ESCs_Mouse | 1.04874077 |
106 | TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 1.04290477 |
107 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.04205903 |
108 | TCF7_22412390_ChIP-Seq_EML_Mouse | 1.03687972 |
109 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 1.03286292 |
110 | SMC3_22415368_ChIP-Seq_MEFs_Mouse | 1.02550080 |
111 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.01563495 |
112 | CTCF_27219007_Chip-Seq_Bcells_Human | 1.01062156 |
113 | NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.00565132 |
114 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.99891549 |
115 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 0.99495406 |
116 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.98938484 |
117 | ATF3_23680149_ChIP-Seq_GBM1-GSC_Human | 0.98439540 |
118 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 0.98138391 |
119 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.97821442 |
120 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 0.97557219 |
121 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 0.97389645 |
122 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.96914494 |
123 | LXR_22292898_ChIP-Seq_THP-1_Human | 0.96349156 |
124 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 0.96280288 |
125 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 0.95856260 |
126 | VDR_21846776_ChIP-Seq_THP-1_Human | 0.95285737 |
127 | SA1_27219007_Chip-Seq_ERYTHROID_Human | 0.95110804 |
128 | RXR_22108803_ChIP-Seq_LS180_Human | 0.94999683 |
129 | EZH2_22144423_ChIP-Seq_EOC_Human | 0.93812951 |
130 | GBX2_23144817_ChIP-Seq_PC3_Human | 0.93549300 |
131 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.93372479 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0008438_abnormal_cutaneous_collagen | 6.50002761 |
2 | MP0005503_abnormal_tendon_morphology | 4.26568251 |
3 | MP0005275_abnormal_skin_tensile | 4.08416497 |
4 | MP0003279_aneurysm | 3.88964320 |
5 | MP0004272_abnormal_basement_membrane | 3.76779890 |
6 | MP0003705_abnormal_hypodermis_morpholog | 3.33154382 |
7 | MP0001958_emphysema | 3.04299692 |
8 | MP0005623_abnormal_meninges_morphology | 2.82029000 |
9 | MP0000751_myopathy | 2.68529749 |
10 | MP0004134_abnormal_chest_morphology | 2.37977722 |
11 | MP0009250_abnormal_appendicular_skeleto | 2.27299133 |
12 | MP0009384_cardiac_valve_regurgitation | 2.18214361 |
13 | MP0003941_abnormal_skin_development | 2.10973326 |
14 | MP0002108_abnormal_muscle_morphology | 2.02812214 |
15 | MP0005508_abnormal_skeleton_morphology | 2.01954138 |
16 | MP0003566_abnormal_cell_adhesion | 1.97222602 |
17 | MP0002282_abnormal_trachea_morphology | 1.94339615 |
18 | MP0003283_abnormal_digestive_organ | 1.93833321 |
19 | MP0002877_abnormal_melanocyte_morpholog | 1.93339816 |
20 | MP0004084_abnormal_cardiac_muscle | 1.87919442 |
21 | MP0000013_abnormal_adipose_tissue | 1.87563010 |
22 | MP0002837_dystrophic_cardiac_calcinosis | 1.83193973 |
23 | * MP0003091_abnormal_cell_migration | 1.76991062 |
24 | MP0001299_abnormal_eye_distance/ | 1.75511879 |
25 | MP0000163_abnormal_cartilage_morphology | 1.69045564 |
26 | MP0002896_abnormal_bone_mineralization | 1.67829842 |
27 | MP0010030_abnormal_orbit_morphology | 1.63838054 |
28 | MP0005257_abnormal_intraocular_pressure | 1.62510836 |
29 | MP0000750_abnormal_muscle_regeneration | 1.56410990 |
30 | MP0002295_abnormal_pulmonary_circulatio | 1.55723683 |
31 | MP0002060_abnormal_skin_morphology | 1.53622294 |
32 | MP0000749_muscle_degeneration | 1.53429836 |
33 | MP0005409_darkened_coat_color | 1.51241188 |
34 | MP0000767_abnormal_smooth_muscle | 1.51152982 |
35 | MP0002933_joint_inflammation | 1.47972998 |
36 | MP0000733_abnormal_muscle_development | 1.47304137 |
37 | MP0005023_abnormal_wound_healing | 1.46315802 |
38 | MP0003385_abnormal_body_wall | 1.44809459 |
39 | MP0006054_spinal_hemorrhage | 1.44070481 |
40 | MP0005330_cardiomyopathy | 1.42708879 |
41 | MP0005670_abnormal_white_adipose | 1.42017372 |
42 | MP0001542_abnormal_bone_strength | 1.41013402 |
43 | MP0002115_abnormal_skeleton_extremities | 1.40596177 |
44 | MP0010368_abnormal_lymphatic_system | 1.33418429 |
45 | MP0005058_abnormal_lysosome_morphology | 1.33310188 |
46 | MP0004087_abnormal_muscle_fiber | 1.31832163 |
47 | MP0001849_ear_inflammation | 1.31271632 |
48 | MP0002249_abnormal_larynx_morphology | 1.26814240 |
49 | MP0000003_abnormal_adipose_tissue | 1.25293453 |
50 | MP0006138_congestive_heart_failure | 1.22274550 |
51 | MP0008775_abnormal_heart_ventricle | 1.21667523 |
52 | MP0005666_abnormal_adipose_tissue | 1.21506589 |
53 | MP0004858_abnormal_nervous_system | 1.18406550 |
54 | MP0005375_adipose_tissue_phenotype | 1.18376504 |
55 | MP0009780_abnormal_chondrocyte_physiolo | 1.16265133 |
56 | MP0002113_abnormal_skeleton_development | 1.15602923 |
57 | MP0002089_abnormal_postnatal_growth/wei | 1.15161944 |
58 | MP0000428_abnormal_craniofacial_morphol | 1.14901442 |
59 | MP0005390_skeleton_phenotype | 1.14745197 |
60 | MP0000762_abnormal_tongue_morphology | 1.14683410 |
61 | MP0004036_abnormal_muscle_relaxation | 1.14078257 |
62 | MP0005408_hypopigmentation | 1.13379307 |
63 | MP0005171_absent_coat_pigmentation | 1.12731438 |
64 | MP0005620_abnormal_muscle_contractility | 1.12131605 |
65 | MP0000759_abnormal_skeletal_muscle | 1.11343265 |
66 | MP0001243_abnormal_dermal_layer | 1.08801937 |
67 | MP0003045_fibrosis | 1.07756862 |
68 | MP0004381_abnormal_hair_follicle | 1.07630384 |
69 | MP0002972_abnormal_cardiac_muscle | 1.07599962 |
70 | MP0003950_abnormal_plasma_membrane | 1.06520822 |
71 | MP0000049_abnormal_middle_ear | 1.06498792 |
72 | MP0003755_abnormal_palate_morphology | 1.06355089 |
73 | MP0004145_abnormal_muscle_electrophysio | 1.06043211 |
74 | MP0004185_abnormal_adipocyte_glucose | 1.05383910 |
75 | MP0000462_abnormal_digestive_system | 1.05013033 |
76 | MP0000534_abnormal_ureter_morphology | 1.03765216 |
77 | MP0000015_abnormal_ear_pigmentation | 1.03269611 |
78 | MP0002128_abnormal_blood_circulation | 1.03071356 |
79 | MP0004510_myositis | 1.02289310 |
80 | MP0005595_abnormal_vascular_smooth | 1.01386494 |
81 | MP0001879_abnormal_lymphatic_vessel | 0.98600647 |
82 | MP0002932_abnormal_joint_morphology | 0.97358917 |
83 | MP0003942_abnormal_urinary_system | 0.96608499 |
84 | MP0005369_muscle_phenotype | 0.96068391 |
85 | MP0004215_abnormal_myocardial_fiber | 0.95816606 |
86 | MP0002116_abnormal_craniofacial_bone | 0.94541473 |
87 | MP0010352_gastrointestinal_tract_polyps | 0.93760501 |
88 | MP0005164_abnormal_response_to | 0.93639516 |
89 | MP0010630_abnormal_cardiac_muscle | 0.92370516 |
90 | MP0000432_abnormal_head_morphology | 0.91969087 |
91 | MP0002269_muscular_atrophy | 0.91866384 |
92 | MP0009278_abnormal_bone_marrow | 0.91506669 |
93 | MP0002109_abnormal_limb_morphology | 0.91066106 |
94 | MP0002998_abnormal_bone_remodeling | 0.90064314 |
95 | MP0003935_abnormal_craniofacial_develop | 0.88765700 |
96 | MP0009840_abnormal_foam_cell | 0.88560750 |
97 | MP0003136_yellow_coat_color | 0.86979001 |
98 | MP0009053_abnormal_anal_canal | 0.85133833 |
99 | MP0001614_abnormal_blood_vessel | 0.84541652 |
100 | MP0005385_cardiovascular_system_phenoty | 0.84499256 |
101 | MP0001544_abnormal_cardiovascular_syste | 0.84499256 |
102 | MP0001915_intracranial_hemorrhage | 0.84475985 |
103 | MP0004130_abnormal_muscle_cell | 0.83456627 |
104 | MP0002233_abnormal_nose_morphology | 0.82881572 |
105 | MP0002168_other_aberrant_phenotype | 0.82452138 |
106 | MP0003646_muscle_fatigue | 0.82097154 |
107 | MP0003115_abnormal_respiratory_system | 0.81665289 |
108 | MP0005197_abnormal_uvea_morphology | 0.80246133 |
109 | MP0004233_abnormal_muscle_weight | 0.79104214 |
110 | MP0001348_abnormal_lacrimal_gland | 0.78932681 |
111 | MP0001270_distended_abdomen | 0.75651374 |
112 | MP0002106_abnormal_muscle_physiology | 0.75461505 |
113 | MP0002925_abnormal_cardiovascular_devel | 0.75086156 |
114 | MP0003795_abnormal_bone_structure | 0.74499471 |
115 | MP0000747_muscle_weakness | 0.74472270 |
116 | MP0001661_extended_life_span | 0.69317901 |
117 | MP0003453_abnormal_keratinocyte_physiol | 0.66675289 |
118 | MP0005165_increased_susceptibility_to | 0.66364937 |
119 | MP0003828_pulmonary_edema | 0.64584722 |
120 | MP0002075_abnormal_coat/hair_pigmentati | 0.63795683 |
121 | MP0005451_abnormal_body_composition | 0.61004442 |
122 | MP0003634_abnormal_glial_cell | 0.60432475 |
123 | MP0002114_abnormal_axial_skeleton | 0.56315872 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Premature rupture of membranes (HP:0001788) | 6.40759211 |
2 | Protrusio acetabuli (HP:0003179) | 6.40609019 |
3 | Epiphyseal dysplasia (HP:0002656) | 4.56172580 |
4 | Ankle contracture (HP:0006466) | 4.43356494 |
5 | Neonatal short-limb short stature (HP:0008921) | 4.27373822 |
6 | Aortic dissection (HP:0002647) | 4.06186847 |
7 | Hypoplastic ischia (HP:0003175) | 4.04464564 |
8 | Type 1 muscle fiber predominance (HP:0003803) | 3.79513795 |
9 | Broad metatarsal (HP:0001783) | 3.71268930 |
10 | Shallow orbits (HP:0000586) | 3.64609150 |
11 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 3.58705899 |
12 | Atrophic scars (HP:0001075) | 3.57423625 |
13 | Abnormality of the ischium (HP:0003174) | 3.51346897 |
14 | Cervical subluxation (HP:0003308) | 3.50389414 |
15 | Increased connective tissue (HP:0009025) | 3.41659985 |
16 | Spinal rigidity (HP:0003306) | 3.32247345 |
17 | Cerebral aneurysm (HP:0004944) | 3.29020026 |
18 | Aortic aneurysm (HP:0004942) | 3.19548860 |
19 | Follicular hyperkeratosis (HP:0007502) | 3.18831023 |
20 | Genu recurvatum (HP:0002816) | 3.16301632 |
21 | Peritonitis (HP:0002586) | 3.09039984 |
22 | Abnormality of dentin (HP:0010299) | 3.08107553 |
23 | Soft skin (HP:0000977) | 3.05979273 |
24 | Round ear (HP:0100830) | 3.01687282 |
25 | Bladder diverticulum (HP:0000015) | 2.99510358 |
26 | Increased variability in muscle fiber diameter (HP:0003557) | 2.92840371 |
27 | Cupped ribs (HP:0000887) | 2.92492905 |
28 | Mild short stature (HP:0003502) | 2.91823823 |
29 | Vascular tortuosity (HP:0004948) | 2.90276904 |
30 | Fragile skin (HP:0001030) | 2.87693667 |
31 | Vitreoretinal degeneration (HP:0000655) | 2.85603253 |
32 | Osteoarthritis (HP:0002758) | 2.84093753 |
33 | Mesomelia (HP:0003027) | 2.83657990 |
34 | Dilatation of the ascending aorta (HP:0005111) | 2.81946810 |
35 | Muscle fiber splitting (HP:0003555) | 2.80656841 |
36 | Wormian bones (HP:0002645) | 2.78007871 |
37 | Mildly elevated creatine phosphokinase (HP:0008180) | 2.73543848 |
38 | Achilles tendon contracture (HP:0001771) | 2.73071335 |
39 | Flat acetabular roof (HP:0003180) | 2.72856187 |
40 | Irregular epiphyses (HP:0010582) | 2.72706412 |
41 | Hip contracture (HP:0003273) | 2.72442187 |
42 | Arterial tortuosity (HP:0005116) | 2.72012086 |
43 | Mitral valve prolapse (HP:0001634) | 2.68134809 |
44 | Blue sclerae (HP:0000592) | 2.62799377 |
45 | Hypoventilation (HP:0002791) | 2.59198799 |
46 | Distal lower limb amyotrophy (HP:0008944) | 2.57168350 |
47 | Biconcave vertebral bodies (HP:0004586) | 2.55514130 |
48 | Wrist flexion contracture (HP:0001239) | 2.54887519 |
49 | Slender build (HP:0001533) | 2.51733493 |
50 | Abnormality of skeletal muscle fiber size (HP:0012084) | 2.50274635 |
51 | Flat capital femoral epiphysis (HP:0003370) | 2.47391589 |
52 | Limited hip movement (HP:0008800) | 2.46531917 |
53 | Distal lower limb muscle weakness (HP:0009053) | 2.44506264 |
54 | Platyspondyly (HP:0000926) | 2.42784341 |
55 | Abnormality of the acetabulum (HP:0003170) | 2.40831281 |
56 | Abnormal vertebral ossification (HP:0100569) | 2.39773542 |
57 | Distal arthrogryposis (HP:0005684) | 2.39617410 |
58 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.39306818 |
59 | Osteolytic defects of the hand bones (HP:0009699) | 2.39306818 |
60 | Spondylolisthesis (HP:0003302) | 2.38728314 |
61 | Coxa vara (HP:0002812) | 2.37246800 |
62 | Abnormality of the Achilles tendon (HP:0005109) | 2.35971025 |
63 | Radial bowing (HP:0002986) | 2.35369784 |
64 | Small epiphyses (HP:0010585) | 2.34764968 |
65 | Ectopia lentis (HP:0001083) | 2.33986393 |
66 | Generalized amyotrophy (HP:0003700) | 2.32101863 |
67 | Mitral regurgitation (HP:0001653) | 2.31448056 |
68 | Overgrowth (HP:0001548) | 2.30796269 |
69 | Stridor (HP:0010307) | 2.25194117 |
70 | Disproportionate tall stature (HP:0001519) | 2.24567875 |
71 | Elbow flexion contracture (HP:0002987) | 2.23960802 |
72 | Broad ribs (HP:0000885) | 2.21240067 |
73 | Hyperacusis (HP:0010780) | 2.20232213 |
74 | Ulnar deviation of the wrist (HP:0003049) | 2.17870527 |
75 | Long toe (HP:0010511) | 2.17563893 |
76 | Ulnar bowing (HP:0003031) | 2.17307064 |
77 | Abnormal ossification of hand bones (HP:0005921) | 2.17170041 |
78 | Lumbar hyperlordosis (HP:0002938) | 2.17132999 |
79 | Infantile muscular hypotonia (HP:0008947) | 2.16503223 |
80 | Mitral stenosis (HP:0001718) | 2.16085748 |
81 | Broad long bones (HP:0005622) | 2.15900527 |
82 | Hyperextensible skin (HP:0000974) | 2.13870403 |
83 | Breech presentation (HP:0001623) | 2.13505089 |
84 | Vertebral compression fractures (HP:0002953) | 2.12064206 |
85 | Joint laxity (HP:0001388) | 2.11653887 |
86 | Tibial bowing (HP:0002982) | 2.11635040 |
87 | Scapular winging (HP:0003691) | 2.11607945 |
88 | Aortic regurgitation (HP:0001659) | 2.11126605 |
89 | Hand muscle atrophy (HP:0009130) | 2.10715647 |
90 | Obstructive sleep apnea (HP:0002870) | 2.10541981 |
91 | White forelock (HP:0002211) | 2.07015210 |
92 | Hypoplasia of the iris (HP:0007676) | 2.06230548 |
93 | Abnormality of carpal bone ossification (HP:0006257) | 2.05987322 |
94 | Spinal cord compression (HP:0002176) | 2.05726222 |
95 | Bowel diverticulosis (HP:0005222) | 2.03508878 |
96 | Delayed epiphyseal ossification (HP:0002663) | 2.01602428 |
97 | Exostoses (HP:0100777) | 2.01077308 |
98 | Upper limb amyotrophy (HP:0009129) | 2.00635188 |
99 | Distal upper limb amyotrophy (HP:0007149) | 2.00635188 |
100 | Wide anterior fontanel (HP:0000260) | 2.00222826 |
101 | Lower limb amyotrophy (HP:0007210) | 1.99488736 |
102 | Metaphyseal cupping (HP:0003021) | 1.99398694 |
103 | Short hallux (HP:0010109) | 1.97629481 |
104 | Short 4th metacarpal (HP:0010044) | 1.97403946 |
105 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 1.97403946 |
106 | Abnormality of the calf musculature (HP:0001430) | 1.97274891 |
107 | Abnormality of the pubic bones (HP:0003172) | 1.97003332 |
108 | Bell-shaped thorax (HP:0001591) | 1.96732970 |
109 | Limb-girdle muscle weakness (HP:0003325) | 1.95711080 |
110 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 1.93134159 |
111 | Difficulty climbing stairs (HP:0003551) | 1.91664725 |
112 | Natal tooth (HP:0000695) | 1.88797518 |
113 | Camptodactyly of toe (HP:0001836) | 1.88356763 |
114 | Bowing of the arm (HP:0006488) | 1.88273584 |
115 | Bowed forearm bones (HP:0003956) | 1.88273584 |
116 | Short nail (HP:0001799) | 1.88152031 |
117 | Aneurysm (HP:0002617) | 1.87984565 |
118 | Abnormality of the proximal phalanges of the hand (HP:0009834) | 1.86983624 |
119 | Trismus (HP:0000211) | 1.86890729 |
120 | Calcaneovalgus deformity (HP:0001848) | 1.85549426 |
121 | Broad phalanx (HP:0006009) | 1.84851174 |
122 | Knee flexion contracture (HP:0006380) | 1.84573701 |
123 | Joint stiffness (HP:0001387) | 1.84429338 |
124 | Venous abnormality (HP:0002624) | 1.83545700 |
125 | Abnormal delivery (HP:0001787) | 1.83099984 |
126 | Limited elbow extension (HP:0001377) | 1.81896708 |
127 | Abnormal hand bone ossification (HP:0010660) | 1.80723326 |
128 | Abnormality of the odontoid process (HP:0003310) | 1.79703951 |
129 | Hypoplasia of the odontoid process (HP:0003311) | 1.79627951 |
130 | Aplasia/Hypoplasia of the hallux (HP:0008362) | 1.79542507 |
131 | Thin ribs (HP:0000883) | 1.78740192 |
132 | Ovoid vertebral bodies (HP:0003300) | 1.78605373 |
133 | Abnormality involving the epiphyses of the lower limbs (HP:0006500) | 1.78353197 |
134 | Abnormality of femoral epiphyses (HP:0006499) | 1.78353197 |
135 | Renal duplication (HP:0000075) | 1.78098199 |
136 | Centrally nucleated skeletal muscle fibers (HP:0003687) | 1.78091831 |
137 | Abnormal foot bone ossification (HP:0010675) | 1.77878854 |
138 | Hallux valgus (HP:0001822) | 1.77547503 |
139 | Broad face (HP:0000283) | 1.77486826 |
140 | Abnormality of the distal phalanges of the toes (HP:0010182) | 1.76510583 |
141 | Deformed tarsal bones (HP:0008119) | 1.76066586 |
142 | Deviation of the hallux (HP:0010051) | 1.75567806 |
143 | Limb-girdle muscle atrophy (HP:0003797) | 1.75018383 |
144 | Muscle fiber inclusion bodies (HP:0100299) | 1.73505786 |
Rank | Gene Set | Z-score |
---|---|---|
1 | DDR2 | 5.83160082 |
2 | TTN | 4.92876310 |
3 | PDGFRA | 4.25541492 |
4 | TRIB3 | 4.17785105 |
5 | MYLK | 2.78217854 |
6 | SIK1 | 2.71472819 |
7 | PKN2 | 2.46689600 |
8 | DMPK | 2.37776604 |
9 | PAK2 | 2.25876563 |
10 | LATS2 | 2.09438548 |
11 | LATS1 | 2.08059306 |
12 | RIPK1 | 1.89422717 |
13 | EPHB2 | 1.88333346 |
14 | CAMK1D | 1.81982942 |
15 | ERBB4 | 1.69888014 |
16 | PDGFRB | 1.57121596 |
17 | CAMK1G | 1.56391113 |
18 | TRPM7 | 1.53774795 |
19 | ROCK1 | 1.51173368 |
20 | BMX | 1.41796714 |
21 | CDK12 | 1.37038526 |
22 | ERN1 | 1.36180912 |
23 | PAK3 | 1.34468000 |
24 | ILK | 1.33028012 |
25 | NEK9 | 1.31291832 |
26 | PIK3CA | 1.29693929 |
27 | SMG1 | 1.26434878 |
28 | PTK2 | 1.22602025 |
29 | PTK6 | 1.21976757 |
30 | PRKD3 | 1.21854706 |
31 | PTK2B | 1.21573614 |
32 | AKT3 | 1.18769855 |
33 | PHKG1 | 1.18261962 |
34 | PHKG2 | 1.18261962 |
35 | FER | 1.17421329 |
36 | MAP3K3 | 1.16289292 |
37 | PRPF4B | 1.13130169 |
38 | EPHA2 | 1.10978076 |
39 | STK38L | 1.07715179 |
40 | CDC42BPA | 1.06835964 |
41 | PRKG2 | 1.06204469 |
42 | CASK | 1.03787556 |
43 | STK24 | 1.03449033 |
44 | TIE1 | 1.03077878 |
45 | EEF2K | 1.01527189 |
46 | MAPKAPK3 | 1.00987021 |
47 | FLT3 | 0.99610050 |
48 | LMTK2 | 0.94538784 |
49 | ARAF | 0.94389660 |
50 | PAK6 | 0.93185746 |
51 | MTOR | 0.91805391 |
52 | MAP3K6 | 0.90711708 |
53 | KIT | 0.89874440 |
54 | NTRK1 | 0.87388579 |
55 | OBSCN | 0.85117074 |
56 | PRKD1 | 0.84693107 |
57 | MAP3K13 | 0.83744610 |
58 | ICK | 0.83265294 |
59 | TAOK1 | 0.82926049 |
60 | KSR2 | 0.82720626 |
61 | FGFR1 | 0.81696056 |
62 | MET | 0.80731770 |
63 | TAOK2 | 0.80598325 |
64 | ROCK2 | 0.80046124 |
65 | MOS | 0.78639297 |
66 | MAP2K3 | 0.77909808 |
67 | TGFBR2 | 0.77439079 |
68 | PRKCH | 0.75803512 |
69 | PDPK1 | 0.74236914 |
70 | IRAK3 | 0.73359823 |
71 | FGFR4 | 0.71411119 |
72 | RET | 0.70616460 |
73 | PIK3CG | 0.69994158 |
74 | LRRK2 | 0.66863723 |
75 | MAP2K1 | 0.65257200 |
76 | PRKD2 | 0.64973644 |
77 | STK3 | 0.62649133 |
78 | PDK2 | 0.60765770 |
79 | DAPK3 | 0.60740215 |
80 | MAP3K1 | 0.56748600 |
81 | MST1R | 0.55445507 |
82 | INSR | 0.54784761 |
83 | PIM2 | 0.53261736 |
84 | FGFR2 | 0.53159392 |
85 | GSK3A | 0.52119146 |
86 | PINK1 | 0.51484584 |
87 | CAMKK1 | 0.50996421 |
88 | MAPK11 | 0.50419872 |
89 | ADRBK1 | 0.50010388 |
90 | LIMK1 | 0.48683026 |
91 | RPS6KA4 | 0.48200040 |
92 | PRKAA2 | 0.48111317 |
93 | CAMK2G | 0.47095958 |
94 | AKT2 | 0.45902777 |
95 | ZAK | 0.45467922 |
96 | TESK1 | 0.45444738 |
97 | PDK3 | 0.45285078 |
98 | PDK4 | 0.45285078 |
99 | ABL2 | 0.44501322 |
100 | PAK4 | 0.43702052 |
101 | EPHB1 | 0.43055441 |
102 | MAP3K7 | 0.42698781 |
103 | EPHA3 | 0.42295547 |
104 | NTRK3 | 0.41722548 |
105 | SRC | 0.41597401 |
106 | SCYL2 | 0.40506931 |
107 | MAP3K10 | 0.40315739 |
108 | RPS6KC1 | 0.40098241 |
109 | RPS6KL1 | 0.40098241 |
110 | ZAP70 | 0.39833220 |
111 | WNK1 | 0.39151490 |
112 | MAPK12 | 0.38243866 |
113 | MARK1 | 0.38073148 |
114 | MAPKAPK5 | 0.36628448 |
115 | MAP3K11 | 0.36596530 |
116 | NEK2 | 0.36384971 |
117 | PAK1 | 0.36218055 |
118 | RPS6KA2 | 0.35193047 |
119 | CDK7 | 0.34609394 |
120 | MARK3 | 0.34501449 |
121 | MAPK4 | 0.34045506 |
122 | NME2 | 0.33328736 |
123 | PRKCE | 0.33254017 |
124 | TYRO3 | 0.33088679 |
125 | ERBB3 | 0.32974585 |
126 | IGF1R | 0.32806367 |
127 | CDK15 | 0.32506272 |
128 | MARK2 | 0.32457652 |
129 | PLK2 | 0.32211166 |
130 | CAMK1 | 0.32071342 |
131 | STK38 | 0.31757968 |
132 | JAK1 | 0.29743742 |
133 | DYRK1B | 0.28969949 |
134 | MAPK7 | 0.28439638 |
135 | NUAK1 | 0.27504585 |
136 | CAMK2D | 0.25848460 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ECM-receptor interaction_Homo sapiens_hsa04512 | 5.13310112 |
2 | Focal adhesion_Homo sapiens_hsa04510 | 3.40404282 |
3 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 3.39958077 |
4 | Protein digestion and absorption_Homo sapiens_hsa04974 | 3.15552275 |
5 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 3.00176126 |
6 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 2.89306344 |
7 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 2.73178052 |
8 | Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.98149799 |
9 | Amoebiasis_Homo sapiens_hsa05146 | 1.88954508 |
10 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.85126304 |
11 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 1.77928717 |
12 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 1.63328740 |
13 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.62921645 |
14 | Adherens junction_Homo sapiens_hsa04520 | 1.53837213 |
15 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.51138501 |
16 | Other glycan degradation_Homo sapiens_hsa00511 | 1.49308356 |
17 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.45704813 |
18 | Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.44448243 |
19 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.44308303 |
20 | Malaria_Homo sapiens_hsa05144 | 1.37785386 |
21 | Hippo signaling pathway_Homo sapiens_hsa04390 | 1.35179322 |
22 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.35031386 |
23 | Basal cell carcinoma_Homo sapiens_hsa05217 | 1.33010030 |
24 | Prion diseases_Homo sapiens_hsa05020 | 1.31940874 |
25 | Glioma_Homo sapiens_hsa05214 | 1.30873331 |
26 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.30073317 |
27 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 1.29800216 |
28 | Bladder cancer_Homo sapiens_hsa05219 | 1.29105998 |
29 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 1.28133090 |
30 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.24996612 |
31 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 1.20092197 |
32 | Gap junction_Homo sapiens_hsa04540 | 1.19952689 |
33 | Melanoma_Homo sapiens_hsa05218 | 1.16648442 |
34 | Viral myocarditis_Homo sapiens_hsa05416 | 1.13483199 |
35 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 1.12110672 |
36 | Tight junction_Homo sapiens_hsa04530 | 1.09979758 |
37 | Axon guidance_Homo sapiens_hsa04360 | 1.07859668 |
38 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 1.06365801 |
39 | Platelet activation_Homo sapiens_hsa04611 | 1.05250419 |
40 | Renin secretion_Homo sapiens_hsa04924 | 1.04842962 |
41 | Rap1 signaling pathway_Homo sapiens_hsa04015 | 0.98357733 |
42 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.98247710 |
43 | Thyroid cancer_Homo sapiens_hsa05216 | 0.97224143 |
44 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.96606017 |
45 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 0.92795128 |
46 | Endometrial cancer_Homo sapiens_hsa05213 | 0.90659645 |
47 | Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 0.90477663 |
48 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 0.87454722 |
49 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 0.87201505 |
50 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.83492880 |
51 | Prostate cancer_Homo sapiens_hsa05215 | 0.82712704 |
52 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 0.81787743 |
53 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.80064530 |
54 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.80054526 |
55 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.79936311 |
56 | Insulin resistance_Homo sapiens_hsa04931 | 0.79567584 |
57 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 0.78853308 |
58 | Pathways in cancer_Homo sapiens_hsa05200 | 0.77923740 |
59 | Melanogenesis_Homo sapiens_hsa04916 | 0.77593283 |
60 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 0.77475139 |
61 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.76839326 |
62 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.76406222 |
63 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.76362907 |
64 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.76178844 |
65 | PPAR signaling pathway_Homo sapiens_hsa03320 | 0.75330684 |
66 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.74444615 |
67 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.72745088 |
68 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.72076202 |
69 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.71714692 |
70 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.70040840 |
71 | Lysosome_Homo sapiens_hsa04142 | 0.69787084 |
72 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.68044255 |
73 | Renal cell carcinoma_Homo sapiens_hsa05211 | 0.67986791 |
74 | Acute myeloid leukemia_Homo sapiens_hsa05221 | 0.67985385 |
75 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.67899472 |
76 | Notch signaling pathway_Homo sapiens_hsa04330 | 0.67573443 |
77 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.67216366 |
78 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.66439900 |
79 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.66279597 |
80 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.65870183 |
81 | Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 0.65833015 |
82 | Sulfur relay system_Homo sapiens_hsa04122 | 0.64498458 |
83 | Salivary secretion_Homo sapiens_hsa04970 | 0.63406700 |
84 | Wnt signaling pathway_Homo sapiens_hsa04310 | 0.63401665 |
85 | Endocytosis_Homo sapiens_hsa04144 | 0.63356260 |
86 | MAPK signaling pathway_Homo sapiens_hsa04010 | 0.62212262 |
87 | Lysine degradation_Homo sapiens_hsa00310 | 0.61747100 |
88 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.60233807 |
89 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.58662754 |
90 | Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 0.56433603 |
91 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.56093728 |
92 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.55732974 |
93 | Ras signaling pathway_Homo sapiens_hsa04014 | 0.55031932 |
94 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.54394099 |
95 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 0.54274026 |
96 | Calcium signaling pathway_Homo sapiens_hsa04020 | 0.52627656 |
97 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.51207776 |
98 | HTLV-I infection_Homo sapiens_hsa05166 | 0.50887131 |
99 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.50649871 |
100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.49668201 |
101 | Circadian entrainment_Homo sapiens_hsa04713 | 0.48864496 |
102 | Cocaine addiction_Homo sapiens_hsa05030 | 0.46862202 |
103 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.46761209 |
104 | Galactose metabolism_Homo sapiens_hsa00052 | 0.46525630 |
105 | Pancreatic cancer_Homo sapiens_hsa05212 | 0.46017323 |
106 | Long-term potentiation_Homo sapiens_hsa04720 | 0.45967426 |
107 | VEGF signaling pathway_Homo sapiens_hsa04370 | 0.45074259 |
108 | Phosphatidylinositol signaling system_Homo sapiens_hsa04070 | 0.44688309 |
109 | Cholinergic synapse_Homo sapiens_hsa04725 | 0.44527104 |
110 | Long-term depression_Homo sapiens_hsa04730 | 0.43451672 |
111 | Tyrosine metabolism_Homo sapiens_hsa00350 | 0.43271985 |
112 | mTOR signaling pathway_Homo sapiens_hsa04150 | 0.42275057 |
113 | Fatty acid degradation_Homo sapiens_hsa00071 | 0.42034453 |
114 | Propanoate metabolism_Homo sapiens_hsa00640 | 0.39703927 |
115 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.39610518 |
116 | Cell adhesion molecules (CAMs)_Homo sapiens_hsa04514 | 0.39543199 |
117 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.39439132 |
118 | Salmonella infection_Homo sapiens_hsa05132 | 0.39275198 |
119 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.38213715 |
120 | Phagosome_Homo sapiens_hsa04145 | 0.37653697 |