CSRP3

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1sarcomere organization (GO:0045214)9.28713246
2* cardiac myofibril assembly (GO:0055003)8.53172514
3negative regulation of potassium ion transmembrane transporter activity (GO:1901017)7.99660487
4muscle filament sliding (GO:0030049)7.87544734
5actin-myosin filament sliding (GO:0033275)7.87544734
6* myofibril assembly (GO:0030239)7.53232477
7negative regulation of potassium ion transmembrane transport (GO:1901380)7.14627593
8* cardiac muscle contraction (GO:0060048)6.84568279
9cardiac muscle cell development (GO:0055013)6.72868012
10tricarboxylic acid cycle (GO:0006099)6.59967541
11actin-mediated cell contraction (GO:0070252)6.54332207
12regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion (GO6.36963552
13cardiac muscle tissue morphogenesis (GO:0055008)6.35235551
14cardiac cell development (GO:0055006)6.32293181
15regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum (GO:0010880)6.27273672
16regulation of relaxation of muscle (GO:1901077)6.25390473
17positive regulation of ryanodine-sensitive calcium-release channel activity (GO:0060316)6.24604356
18ventricular cardiac muscle tissue morphogenesis (GO:0055010)6.03959420
19regulation of actin filament-based movement (GO:1903115)6.03568675
20heart process (GO:0003015)5.83486376
21heart contraction (GO:0060047)5.83486376
22adult heart development (GO:0007512)5.81981683
23regulation of sarcomere organization (GO:0060297)5.79891483
24bundle of His cell to Purkinje myocyte communication (GO:0086069)5.78716400
25* actomyosin structure organization (GO:0031032)5.75186447
26muscle tissue morphogenesis (GO:0060415)5.72020968
27regulation of skeletal muscle contraction (GO:0014819)5.71385545
28ventricular cardiac muscle cell action potential (GO:0086005)5.67424838
29plasma membrane repair (GO:0001778)5.60964911
30regulation of cardiac muscle contraction by calcium ion signaling (GO:0010882)5.59155968
31heart trabecula formation (GO:0060347)5.39706935
32* striated muscle contraction (GO:0006941)5.35765301
33regulation of acetyl-CoA biosynthetic process from pyruvate (GO:0010510)5.31262550
34* cardiac muscle hypertrophy (GO:0003300)5.25922760
35regulation of ventricular cardiac muscle cell membrane repolarization (GO:0060307)5.21690862
36mitochondrial ATP synthesis coupled proton transport (GO:0042776)5.08380946
37response to muscle activity (GO:0014850)5.01522687
38regulation of striated muscle contraction (GO:0006942)5.00844272
39* striated muscle hypertrophy (GO:0014897)4.96660302
40carnitine shuttle (GO:0006853)4.94852400
41actin filament-based movement (GO:0030048)4.87576149
42regulation of acyl-CoA biosynthetic process (GO:0050812)4.81609858
43regulation of cell communication by electrical coupling (GO:0010649)4.78847561
44sarcoplasmic reticulum calcium ion transport (GO:0070296)4.78516794
45energy coupled proton transport, down electrochemical gradient (GO:0015985)4.72523965
46ATP synthesis coupled proton transport (GO:0015986)4.72523965
47regulation of ryanodine-sensitive calcium-release channel activity (GO:0060314)4.71687233
48cell communication by electrical coupling involved in cardiac conduction (GO:0086064)4.59307486
49negative regulation of cardiac muscle cell apoptotic process (GO:0010667)4.54487934
50oxidative phosphorylation (GO:0006119)4.51925595
51cell communication involved in cardiac conduction (GO:0086065)4.49612662
52regulation of membrane repolarization (GO:0060306)4.45476904
53mitochondrial electron transport, NADH to ubiquinone (GO:0006120)4.42825222
54regulation of coenzyme metabolic process (GO:0051196)4.42432180
55regulation of cofactor metabolic process (GO:0051193)4.42432180
56* regulation of the force of heart contraction (GO:0002026)4.41983956
57respiratory electron transport chain (GO:0022904)4.40792910
58* muscle hypertrophy (GO:0014896)4.37671896
59fatty acid transmembrane transport (GO:1902001)4.37603397
60cardiac muscle adaptation (GO:0014887)4.36528030
61cardiac muscle hypertrophy in response to stress (GO:0014898)4.36528030
62muscle hypertrophy in response to stress (GO:0003299)4.36528030
63electron transport chain (GO:0022900)4.28111966
64response to stimulus involved in regulation of muscle adaptation (GO:0014874)4.25628328
65regulation of cardioblast differentiation (GO:0051890)4.25550161
66negative regulation of striated muscle cell apoptotic process (GO:0010664)4.21245194
67skeletal muscle adaptation (GO:0043501)4.11898423
68muscle fiber development (GO:0048747)4.10898955
69regulation of ATPase activity (GO:0043462)4.05677395
70regulation of ATP catabolic process (GO:1903289)4.05677395
71cardiac chamber formation (GO:0003207)4.04815244
72regulation of cardiac muscle contraction (GO:0055117)4.02380169
73ventricular cardiac muscle cell development (GO:0055015)4.00383271
74regulation of calcium ion transmembrane transporter activity (GO:1901019)3.98926603
75regulation of calcium ion transmembrane transport (GO:1903169)3.98926603
76regulation of cardiac muscle cell contraction (GO:0086004)3.98569164
77skeletal muscle fiber development (GO:0048741)3.97188527
78cardiac muscle cell action potential involved in contraction (GO:0086002)3.96661857
79regulation of heart rate (GO:0002027)3.96289767
80negative regulation of protein localization to cell surface (GO:2000009)3.93420582
81cardiac muscle cell action potential (GO:0086001)3.92906890
82cell communication by electrical coupling (GO:0010644)3.90731842
832-oxoglutarate metabolic process (GO:0006103)3.88853077
84cardiac ventricle formation (GO:0003211)3.87591988
85negative regulation of potassium ion transport (GO:0043267)3.82652227
86striated muscle cell development (GO:0055002)3.82022548
87NADH metabolic process (GO:0006734)3.78435441
88myotube cell development (GO:0014904)3.77554994
89relaxation of cardiac muscle (GO:0055119)3.73749596
90negative regulation of calcium ion transmembrane transporter activity (GO:1901020)3.67481826
91negative regulation of calcium ion transmembrane transport (GO:1903170)3.67481826
92membrane depolarization during cardiac muscle cell action potential (GO:0086012)3.66961103
93glycogen catabolic process (GO:0005980)3.64763528
94muscle adaptation (GO:0043500)3.64472992
95regulation of muscle system process (GO:0090257)3.63585897
96carnitine transmembrane transport (GO:1902603)3.63487962
97regulation of sulfur metabolic process (GO:0042762)3.62908458
98glycogen biosynthetic process (GO:0005978)3.58426317
99glucan biosynthetic process (GO:0009250)3.58426317
100relaxation of muscle (GO:0090075)3.57244677
101regulation of sequestering of triglyceride (GO:0010889)3.56592018
102muscle cell cellular homeostasis (GO:0046716)3.55035980
103positive regulation of calcium ion transmembrane transporter activity (GO:1901021)3.54599647
104* regulation of heart contraction (GO:0008016)3.54065578
105creatine metabolic process (GO:0006600)3.51434772
106cardiac conduction (GO:0061337)3.48934471
107regulation of calcineurin-NFAT signaling cascade (GO:0070884)3.46530194
108trabecula formation (GO:0060343)3.45699716
109* muscle contraction (GO:0006936)3.45682473
110positive regulation of cation channel activity (GO:2001259)3.44944907
111glucan catabolic process (GO:0009251)3.41629417
112regulation of muscle contraction (GO:0006937)3.40584754
113striated muscle adaptation (GO:0014888)3.40291517
114response to inactivity (GO:0014854)3.38909921
115regulation of heart rate by cardiac conduction (GO:0086091)3.37844984
116muscle cell fate commitment (GO:0042693)3.35139010
117regulation of myoblast differentiation (GO:0045661)3.33409901
118negative regulation of ryanodine-sensitive calcium-release channel activity (GO:0060315)3.32125607
119amino-acid betaine transport (GO:0015838)3.31537989
120carnitine transport (GO:0015879)3.31537989
121skeletal muscle contraction (GO:0003009)3.31368571
122positive regulation of heart rate (GO:0010460)3.30984607
123regulation of striated muscle cell apoptotic process (GO:0010662)3.30420936
124response to caffeine (GO:0031000)3.30234581
125* skeletal muscle tissue development (GO:0007519)3.28351659
126muscle cell development (GO:0055001)3.27200171
127* muscle system process (GO:0003012)3.26941353
128cellular polysaccharide catabolic process (GO:0044247)3.21956560

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1PPARG_19300518_ChIP-PET_3T3-L1_Mouse7.73856564
2* EP300_21415370_ChIP-Seq_HL-1_Mouse5.29212195
3ESRRB_18555785_ChIP-Seq_MESCs_Mouse5.01590704
4TBX20_22328084_ChIP-Seq_HEART_Mouse4.26289016
5TBX20_22080862_ChIP-Seq_HEART_Mouse4.26289016
6RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse4.23242541
7TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse4.22622488
8ESR1_17901129_ChIP-ChIP_LIVER_Mouse3.60209100
9* MEF2A_21415370_ChIP-Seq_HL-1_Mouse3.37716046
10CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human3.27007141
11ESR1_20079471_ChIP-ChIP_T-47D_Human3.18857116
12ZNF263_19887448_ChIP-Seq_K562_Human2.98492648
13GATA4_21415370_ChIP-Seq_HL-1_Mouse2.82255408
14TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse2.76724218
15BP1_19119308_ChIP-ChIP_Hs578T_Human2.70993819
16RARG_19884340_ChIP-ChIP_MEFs_Mouse2.68159290
17NR1I2_20693526_ChIP-Seq_LIVER_Mouse2.40260560
18* PPARA_22158963_ChIP-Seq_LIVER_Mouse2.09840217
19EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse2.09692650
20PPARD_23208498_ChIP-Seq_MDA-MB-231_Human2.02616804
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse2.02559968
22GATA1_22025678_ChIP-Seq_K562_Human2.00383912
23* NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.96538977
24RXR_22158963_ChIP-Seq_LIVER_Mouse1.91312873
25FOXO1_23066095_ChIP-Seq_LIVER_Mouse1.90951472
26CLOCK_20551151_ChIP-Seq_293T_Human1.90846112
27* LXR_22158963_ChIP-Seq_LIVER_Mouse1.90368804
28THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse1.83587079
29PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse1.76162808
30CDX2_19796622_ChIP-Seq_MESCs_Mouse1.76133263
31PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.75665588
32ZNF652_21678463_ChIP-ChIP_ZR75-1_Human1.58321331
33TRIM28_21343339_ChIP-Seq_HEK293_Human1.58262512
34NR0B1_18358816_ChIP-ChIP_MESCs_Mouse1.56721881
35ESR2_21235772_ChIP-Seq_MCF-7_Human1.50549764
36TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human1.47403338
37NFIB_24661679_ChIP-Seq_LUNG_Mouse1.43361250
38BCL3_23251550_ChIP-Seq_MUSCLE_Mouse1.27088343
39ISL1_27105846_Chip-Seq_CPCs_Mouse1.25227822
40EZH2_27294783_Chip-Seq_ESCs_Mouse1.24367995
41CREB1_26743006_Chip-Seq_LNCaP-abl_Human1.22126231
42HIF1A_21447827_ChIP-Seq_MCF-7_Human1.20151447
43TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse1.17595516
44BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human1.16954497
45VDR_22108803_ChIP-Seq_LS180_Human1.13747830
46EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.11883576
47PPAR_26484153_Chip-Seq_NCI-H1993_Human1.11726316
48GATA1_19941826_ChIP-Seq_K562_Human1.10113599
49* PBX_27287812_Chip-Seq_EMBYONIC-LIMB_Mouse1.09533547
50GATA2_21666600_ChIP-Seq_HMVEC_Human1.09500131
51CTCF_27219007_Chip-Seq_Bcells_Human1.07964317
52EZH2_27304074_Chip-Seq_ESCs_Mouse1.07304849
53SPI1_20517297_ChIP-Seq_HL60_Human1.05721026
54STAT3_1855785_ChIP-Seq_MESCs_Mouse1.03949482
55SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse1.03260626
56ESR1_22446102_ChIP-Seq_UTERUS_Mouse1.03090202
57AUTS2_25519132_ChIP-Seq_293T-REX_Human1.02986222
58SRF_21415370_ChIP-Seq_HL-1_Mouse1.02972304
59CBX2_27304074_Chip-Seq_ESCs_Mouse1.02893420
60DROSHA_22980978_ChIP-Seq_HELA_Human1.00972234
61* TP63_22573176_ChIP-Seq_HFKS_Human1.00478880
62SUZ12_18692474_ChIP-Seq_MEFs_Mouse0.98030178
63* RUNX2_24764292_ChIP-Seq_MC3T3_Mouse0.97339936
64ATF3_27146783_Chip-Seq_COLON_Human0.96596807
65RARB_27405468_Chip-Seq_BRAIN_Mouse0.96549041
66KDM2B_26808549_Chip-Seq_SUP-B15_Human0.96246574
67TFAP2C_20629094_ChIP-Seq_MCF-7_Human0.95524175
68EZH2_22144423_ChIP-Seq_EOC_Human0.95102313
69GBX2_23144817_ChIP-Seq_PC3_Human0.94272793
70ZNF274_21170338_ChIP-Seq_K562_Hela0.94045864
71TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse0.93073963
72MTF2_20144788_ChIP-Seq_MESCs_Mouse0.92568761
73RACK7_27058665_Chip-Seq_MCF-7_Human0.91708837
74SMC3_22415368_ChIP-Seq_MEFs_Mouse0.90445916
75ELK3_25401928_ChIP-Seq_HUVEC_Human0.90442547
76RNF2_18974828_ChIP-Seq_MESCs_Mouse0.90023974
77EZH2_18974828_ChIP-Seq_MESCs_Mouse0.90023974
78NRF2_20460467_ChIP-Seq_MEFs_Mouse0.89491545
79NFE2L2_20460467_ChIP-Seq_MEFs_Mouse0.89491545
80SMAD4_21741376_ChIP-Seq_HESCs_Human0.88614660
81SUZ12_27294783_Chip-Seq_NPCs_Mouse0.88407421
82STAT3_19079543_ChIP-ChIP_MESCs_Mouse0.88391790
83SOX2_21211035_ChIP-Seq_LN229_Gbm0.87912064
84FOXA2_19822575_ChIP-Seq_HepG2_Human0.87839726
85LYL1_20887958_ChIP-Seq_HPC-7_Mouse0.87720613
86OCT4_20526341_ChIP-Seq_ESCs_Human0.87633194
87EZH2_27294783_Chip-Seq_NPCs_Mouse0.87480952
88MYC_27129775_Chip-Seq_CORNEA_Mouse0.87446098
89KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.87342485
90KDM2B_26808549_Chip-Seq_DND41_Human0.86728002
91HTT_18923047_ChIP-ChIP_STHdh_Human0.86431833
92NR3C1_23031785_ChIP-Seq_PC12_Mouse0.86258664
93SUZ12_18555785_ChIP-Seq_MESCs_Mouse0.86189931
94TBX5_21415370_ChIP-Seq_HL-1_Mouse0.85390607
95CRX_20693478_ChIP-Seq_RETINA_Mouse0.85295073
96GATA2_19941826_ChIP-Seq_K562_Human0.83589811
97GATA3_20176728_ChIP-ChIP_TSCs_Mouse0.83261009
98WT1_25993318_ChIP-Seq_PODOCYTE_Human0.83167105
99SUZ12_18692474_ChIP-Seq_MESCs_Mouse0.83053908
100SMAD4_21799915_ChIP-Seq_A2780_Human0.82096124
101GF1_26923725_Chip-Seq_HPCs_Mouse0.81777611
102ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.81705327
103E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse0.81505382
104SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse0.81127073
105IGF1R_20145208_ChIP-Seq_DFB_Human0.80891842
106HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.79551994
107SOX9_24532713_ChIP-Seq_HFSC_Mouse0.79226739
108PCGF2_27294783_Chip-Seq_NPCs_Mouse0.78429409
109RUNX1_27514584_Chip-Seq_MCF-7_Human0.78192674
110PRDM14_21183938_ChIP-Seq_MESCs_Mouse0.78013551
111GATA1_19941827_ChIP-Seq_MEL_Mouse0.78008718
112LXR_22292898_ChIP-Seq_THP-1_Human0.77965674
113CJUN_26792858_Chip-Seq_BT549_Human0.77727029
114NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse0.77481101
115P68_20966046_ChIP-Seq_HELA_Human0.77410828
116PPARG_20176806_ChIP-Seq_3T3-L1_Mouse0.76708542
117GLI1_17442700_ChIP-ChIP_MESCs_Mouse0.76706596
118FOXH1_21741376_ChIP-Seq_ESCs_Human0.75815245
119BCAT_22108803_ChIP-Seq_LS180_Human0.75010095
120* PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human0.74965892
121GATA6_21074721_ChIP-Seq_CACO-2_Mouse0.74931995
122JARID2_20075857_ChIP-Seq_MESCs_Mouse0.74421966
123SALL4_18804426_ChIP-ChIP_XEN_Mouse0.73849556
124TP53_23651856_ChIP-Seq_MEFs_Mouse0.73537972
125TBL1_22424771_ChIP-Seq_293T_Human0.72124201
126PCGF2_27294783_Chip-Seq_ESCs_Mouse0.72080194
127BCL6_27268052_Chip-Seq_Bcells_Human0.72032440
128TCF7L2_21901280_ChIP-Seq_H4IIE_Rat0.71514128
129OCT4_21477851_ChIP-Seq_ESCs_Mouse0.71358507
130CDX2_21074721_ChIP-Seq_CACO-2_Mouse0.70867274
131CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse0.70549158
132RBPJ_22232070_ChIP-Seq_NCS_Mouse0.70508784
133SMAD3_21741376_ChIP-Seq_HESCs_Human0.70273295
134CTCF_21964334_Chip-Seq_Bcells_Human0.69852686
135GATA1_19941827_ChIP-Seq_MEL86_Mouse0.69357855
136SMAD3_22036565_ChIP-Seq_ESCs_Mouse0.68315649
137WT1_19549856_ChIP-ChIP_CCG9911_Human0.68027612
138CTNNB1_20460455_ChIP-Seq_HCT116_Human0.67527847
139ESR1_21235772_ChIP-Seq_MCF-7_Human0.67524022
140GATA1_21571218_ChIP-Seq_MEGAKARYOCYTES_Human0.67344602
141UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human0.67007263
142ZFP281_18757296_ChIP-ChIP_E14_Mouse0.66050218
143* TRIM28_17542650_ChIP-ChIP_NTERA2_Human0.65969576
144EGR1_19032775_ChIP-ChIP_M12_Human0.65612539
145CEBPB_24764292_ChIP-Seq_MC3T3_Mouse0.65593126
146EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse0.65202270
147DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.65120784

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002837_dystrophic_cardiac_calcinosis6.58341909
2MP0004084_abnormal_cardiac_muscle6.17574352
3MP0003646_muscle_fatigue5.29472639
4MP0000751_myopathy4.90132870
5MP0004215_abnormal_myocardial_fiber4.74963901
6MP0004036_abnormal_muscle_relaxation4.47150172
7MP0000749_muscle_degeneration4.23146431
8* MP0005330_cardiomyopathy3.89413612
9* MP0002972_abnormal_cardiac_muscle3.26194788
10MP0008775_abnormal_heart_ventricle3.14871601
11* MP0004087_abnormal_muscle_fiber3.10312638
12MP0003137_abnormal_impulse_conducting2.92163123
13MP0001544_abnormal_cardiovascular_syste2.74477743
14MP0005385_cardiovascular_system_phenoty2.74477743
15* MP0010630_abnormal_cardiac_muscle2.69585714
16* MP0005620_abnormal_muscle_contractility2.69550655
17MP0000750_abnormal_muscle_regeneration2.56014263
18MP0006138_congestive_heart_failure2.55186559
19MP0002106_abnormal_muscle_physiology2.51318230
20MP0004484_altered_response_of2.48480681
21MP0003828_pulmonary_edema2.34763718
22MP0004130_abnormal_muscle_cell2.34588693
23MP0002269_muscular_atrophy2.31814576
24MP0003221_abnormal_cardiomyocyte_apopto2.27552491
25MP0004145_abnormal_muscle_electrophysio2.23855196
26MP0004510_myositis2.09870805
27* MP0004085_abnormal_heartbeat2.09441499
28MP0005369_muscle_phenotype2.01985202
29MP0000747_muscle_weakness1.97602704
30MP0006036_abnormal_mitochondrial_physio1.90448005
31MP0000759_abnormal_skeletal_muscle1.89815948
32MP0002127_abnormal_cardiovascular_syste1.87612087
33MP0003950_abnormal_plasma_membrane1.74731294
34MP0004233_abnormal_muscle_weight1.59751252
35MP0003567_abnormal_fetal_cardiomyocyte1.49950406
36MP0002332_abnormal_exercise_endurance1.40123283
37MP0005666_abnormal_adipose_tissue1.23876294
38MP0010368_abnormal_lymphatic_system1.20278041
39* MP0000266_abnormal_heart_morphology1.18043451
40MP0000343_altered_response_to1.16982684
41MP0003806_abnormal_nucleotide_metabolis1.12449488
42MP0005451_abnormal_body_composition1.12274715
43MP0006035_abnormal_mitochondrial_morpho1.10367693
44MP0005670_abnormal_white_adipose1.07974423
45MP0003279_aneurysm1.06717450
46MP0005165_increased_susceptibility_to1.04245695
47MP0002234_abnormal_pharynx_morphology1.03736888
48MP0001661_extended_life_span0.93505251
49MP0005266_abnormal_metabolism0.87030631
50MP0000230_abnormal_systemic_arterial0.85835117
51MP0002128_abnormal_blood_circulation0.84351425
52MP0003566_abnormal_cell_adhesion0.82978109
53MP0005375_adipose_tissue_phenotype0.79754639
54MP0004185_abnormal_adipocyte_glucose0.78092960
55MP0004270_analgesia0.77664533
56MP0002108_abnormal_muscle_morphology0.75213773
57MP0003705_abnormal_hypodermis_morpholog0.71911538
58MP0000767_abnormal_smooth_muscle0.64941431
59MP0001879_abnormal_lymphatic_vessel0.62724571
60MP0004272_abnormal_basement_membrane0.60557930
61MP0005319_abnormal_enzyme/_coenzyme0.59111095
62MP0002822_catalepsy0.58930917
63MP0005085_abnormal_gallbladder_physiolo0.58906156
64MP0003045_fibrosis0.58830750
65MP0000733_abnormal_muscle_development0.55879439
66MP0002909_abnormal_adrenal_gland0.54996292
67MP0009780_abnormal_chondrocyte_physiolo0.52052869
68MP0005623_abnormal_meninges_morphology0.51608913
69MP0004043_abnormal_pH_regulation0.50857501
70MP0000013_abnormal_adipose_tissue0.49970009
71MP0003984_embryonic_growth_retardation0.49835297
72MP0002971_abnormal_brown_adipose0.49653656
73MP0002925_abnormal_cardiovascular_devel0.49558758
74MP0002088_abnormal_embryonic_growth/wei0.49360897
75MP0009384_cardiac_valve_regurgitation0.48888678
76MP0001299_abnormal_eye_distance/0.48239816
77MP0005275_abnormal_skin_tensile0.46391712
78MP0004147_increased_porphyrin_level0.46311767
79MP0000003_abnormal_adipose_tissue0.43545569
80MP0008569_lethality_at_weaning0.42876910
81MP0002078_abnormal_glucose_homeostasis0.42205088
82MP0005187_abnormal_penis_morphology0.40578651
83MP0001784_abnormal_fluid_regulation0.40258761
84MP0008438_abnormal_cutaneous_collagen0.40214133
85MP0001614_abnormal_blood_vessel0.40028977
86MP0000372_irregular_coat_pigmentation0.37167532
87MP0005332_abnormal_amino_acid0.35858575
88MP0009840_abnormal_foam_cell0.35456189
89MP0005083_abnormal_biliary_tract0.33000443
90MP0002638_abnormal_pupillary_reflex0.32515124
91MP0003195_calcinosis0.32112223
92MP0005584_abnormal_enzyme/coenzyme_acti0.32093824
93MP0003948_abnormal_gas_homeostasis0.30015383
94MP0005595_abnormal_vascular_smooth0.29990630
95MP0000762_abnormal_tongue_morphology0.29963686
96MP0002118_abnormal_lipid_homeostasis0.29848644
97MP0005535_abnormal_body_temperature0.29697515
98MP0001672_abnormal_embryogenesis/_devel0.26731635
99MP0005380_embryogenesis_phenotype0.26731635
100MP0008961_abnormal_basal_metabolism0.26558877
101MP0004134_abnormal_chest_morphology0.24980943
102MP0005376_homeostasis/metabolism_phenot0.24435510
103MP0001727_abnormal_embryo_implantation0.24198871
104MP0000249_abnormal_blood_vessel0.22711505
105MP0005167_abnormal_blood-brain_barrier0.22157516
106MP0003656_abnormal_erythrocyte_physiolo0.22056566
107MP0003941_abnormal_skin_development0.21230589
108MP0005503_abnormal_tendon_morphology0.20755084
109MP0005334_abnormal_fat_pad0.20087000
110MP0002133_abnormal_respiratory_system0.20086776
111MP0005388_respiratory_system_phenotype0.20086776
112MP0003879_abnormal_hair_cell0.18580935
113MP0009250_abnormal_appendicular_skeleto0.17779321
114MP0005452_abnormal_adipose_tissue0.16944602
115MP0008874_decreased_physiological_sensi0.16312711
116MP0010030_abnormal_orbit_morphology0.16244450
117MP0002114_abnormal_axial_skeleton0.15989121
118MP0005166_decreased_susceptibility_to0.15664985
119MP0009672_abnormal_birth_weight0.15371699
120MP0000579_abnormal_nail_morphology0.15347092
121MP0005386_behavior/neurological_phenoty0.15224427
122MP0004924_abnormal_behavior0.15224427
123MP0001984_abnormal_olfaction0.14909236
124MP0002896_abnormal_bone_mineralization0.14798925

Predicted human phenotypes

RankGene SetZ-score
1Sudden death (HP:0001699)8.12935033
2Calf muscle hypertrophy (HP:0008981)6.40118108
3* Ventricular tachycardia (HP:0004756)6.38725052
4Exercise-induced muscle cramps (HP:0003710)6.08082642
5* Atrial fibrillation (HP:0005110)5.84314247
6Exercise-induced myalgia (HP:0003738)5.83434548
7Muscle hypertrophy of the lower extremities (HP:0008968)5.79673823
8* Primary atrial arrhythmia (HP:0001692)5.43701812
9* Lipoatrophy (HP:0100578)5.34079570
10Abnormality of the calf musculature (HP:0001430)5.29865277
11* Supraventricular tachycardia (HP:0004755)5.26520622
12Muscle fiber splitting (HP:0003555)5.24747829
13Subaortic stenosis (HP:0001682)5.23227875
14Abnormality of the left ventricular outflow tract (HP:0011103)5.23227875
15* Supraventricular arrhythmia (HP:0005115)5.15383699
16Right ventricular cardiomyopathy (HP:0011663)5.14923379
17Hyporeflexia of lower limbs (HP:0002600)5.05390954
18Myoglobinuria (HP:0002913)4.90953300
19Distal arthrogryposis (HP:0005684)4.89580472
20Syncope (HP:0001279)4.77815155
21Palpitations (HP:0001962)4.48428643
22* Dilated cardiomyopathy (HP:0001644)4.41098763
23Bundle branch block (HP:0011710)4.38229372
24Myopathic facies (HP:0002058)4.37855176
25Prolonged QT interval (HP:0001657)4.24540860
26EMG: myopathic abnormalities (HP:0003458)4.23233920
27Ventricular arrhythmia (HP:0004308)4.18781949
28Asymmetric septal hypertrophy (HP:0001670)4.07954155
29Round ear (HP:0100830)4.06148687
30Rhabdomyolysis (HP:0003201)3.86436142
31Heart block (HP:0012722)3.73629801
32Ulnar deviation of the wrist (HP:0003049)3.72987664
33Atrioventricular block (HP:0001678)3.58448015
34Increased connective tissue (HP:0009025)3.57682076
35Ventricular fibrillation (HP:0001663)3.54309280
36Abnormal atrioventricular conduction (HP:0005150)3.51825991
37Hepatic necrosis (HP:0002605)3.33437204
38Abnormal mitochondria in muscle tissue (HP:0008316)3.29634438
39Acute necrotizing encephalopathy (HP:0006965)3.28553817
40Calcaneovalgus deformity (HP:0001848)3.20040091
41Myotonia (HP:0002486)3.08657982
42Abnormal EKG (HP:0003115)3.05704120
43Frequent falls (HP:0002359)3.05308546
44Difficulty running (HP:0009046)3.01083526
45Left ventricular hypertrophy (HP:0001712)2.99876458
46Absent phalangeal crease (HP:0006109)2.93849634
47Hypoglycemic coma (HP:0001325)2.91931774
48Hepatocellular necrosis (HP:0001404)2.88578564
49Distal lower limb muscle weakness (HP:0009053)2.85163805
50Acute encephalopathy (HP:0006846)2.84926703
51Type 1 muscle fiber predominance (HP:0003803)2.83939663
52Ragged-red muscle fibers (HP:0003200)2.83064188
53Deformed tarsal bones (HP:0008119)2.81680319
54Ketoacidosis (HP:0001993)2.77472566
55Distal lower limb amyotrophy (HP:0008944)2.75969361
56Mitochondrial inheritance (HP:0001427)2.73186705
57* Palmoplantar keratoderma (HP:0000982)2.72456375
58Progressive macrocephaly (HP:0004481)2.71643873
59Conjunctival hamartoma (HP:0100780)2.71408974
60Cerebral edema (HP:0002181)2.65713315
61Increased CSF lactate (HP:0002490)2.62851374
62Muscle fiber cytoplasmatic inclusion bodies (HP:0100303)2.58363448
63Neck muscle weakness (HP:0000467)2.57156627
64Muscle fiber inclusion bodies (HP:0100299)2.56917628
65Abnormality of fatty-acid metabolism (HP:0004359)2.56076485
66Areflexia of lower limbs (HP:0002522)2.54206548
67Dicarboxylic aciduria (HP:0003215)2.53478257
68Abnormality of dicarboxylic acid metabolism (HP:0010995)2.53478257
69Difficulty climbing stairs (HP:0003551)2.50483078
70Increased muscle lipid content (HP:0009058)2.50437148
71Bulbar palsy (HP:0001283)2.43420561
72Scapular winging (HP:0003691)2.43331012
73Exercise intolerance (HP:0003546)2.41654888
74Abnormal finger flexion creases (HP:0006143)2.40449891
75Malignant hyperthermia (HP:0002047)2.40368751
76Muscle stiffness (HP:0003552)2.39961524
77Gowers sign (HP:0003391)2.35675402
78Lactic acidosis (HP:0003128)2.29108726
79Progressive muscle weakness (HP:0003323)2.28239011
80Rimmed vacuoles (HP:0003805)2.26039535
81Increased intramyocellular lipid droplets (HP:0012240)2.24649655
82Weak cry (HP:0001612)2.23762981
83Increased variability in muscle fiber diameter (HP:0003557)2.22999111
84Hip contracture (HP:0003273)2.22457709
85Pheochromocytoma (HP:0002666)2.21547713
86Limb-girdle muscle atrophy (HP:0003797)2.21212462
87Increased serum pyruvate (HP:0003542)2.20978502
88Abnormality of glycolysis (HP:0004366)2.20978502
89Respiratory failure (HP:0002878)2.20841842
90Abnormality of the foot musculature (HP:0001436)2.15051919
91Ketosis (HP:0001946)2.14339468
92Neoplasm of the adrenal gland (HP:0100631)2.13834496
93EMG: neuropathic changes (HP:0003445)2.11068965
94Abnormality of skeletal muscle fiber size (HP:0012084)2.10972552
95Lower limb amyotrophy (HP:0007210)2.07838538
96Double outlet right ventricle (HP:0001719)2.07317522
97Congenital malformation of the right heart (HP:0011723)2.07317522
98Generalized muscle weakness (HP:0003324)2.05941880
99Centrally nucleated skeletal muscle fibers (HP:0003687)2.04558299
100Fetal akinesia sequence (HP:0001989)2.03800131
101Nemaline bodies (HP:0003798)2.03274464
102Hamartoma of the eye (HP:0010568)2.02150579
103Testicular atrophy (HP:0000029)2.01756698
104Abnormality of the shoulder girdle musculature (HP:0001435)2.01588626
105Neuroendocrine neoplasm (HP:0100634)2.00578463
106Proximal amyotrophy (HP:0007126)2.00279446
107Abnormality of alanine metabolism (HP:0010916)1.99296504
108Hyperalaninemia (HP:0003348)1.99296504
109Abnormality of pyruvate family amino acid metabolism (HP:0010915)1.99296504
110Generalized aminoaciduria (HP:0002909)1.97140508
111Foot dorsiflexor weakness (HP:0009027)1.95861677
112Mildly elevated creatine phosphokinase (HP:0008180)1.95294195
113Fatigable weakness (HP:0003473)1.94688716
114Abnormality of the neuromuscular junction (HP:0003398)1.94688716
115Waddling gait (HP:0002515)1.94648578
116Neoplasm of head and neck (HP:0012288)1.92367838
117Esophageal neoplasm (HP:0100751)1.92367838
118* Congestive heart failure (HP:0001635)1.92162153
119Spinal rigidity (HP:0003306)1.90458006
120Slender build (HP:0001533)1.89672278
121* Sudden cardiac death (HP:0001645)1.88516283
122Lipid accumulation in hepatocytes (HP:0006561)1.86627179
123Steppage gait (HP:0003376)1.84328026
124Hypoplastic left heart (HP:0004383)1.82473892
125Respiratory insufficiency due to muscle weakness (HP:0002747)1.82375718
126Hyperammonemia (HP:0001987)1.81617322
127Hyperinsulinemic hypoglycemia (HP:0000825)1.81370536
128Muscular dystrophy (HP:0003560)1.81253843
129Abnormality of the calcaneus (HP:0008364)1.78672017
130Hypoplastic heart (HP:0001961)1.68531922
131Hyperkalemia (HP:0002153)1.67731955
132Limb-girdle muscle weakness (HP:0003325)1.57454680
133Limited hip movement (HP:0008800)1.51829797
134Facial diplegia (HP:0001349)1.50474312
135Abnormality of the musculature of the pelvis (HP:0001469)1.45264316
136Abnormality of the hip-girdle musculature (HP:0001445)1.45264316
137Aplasia of the musculature (HP:0100854)1.43133266
138Type 2 muscle fiber atrophy (HP:0003554)1.41574561

Predicted kinase interactions (KEA)

RankGene SetZ-score
1OBSCN5.96912902
2TTN5.37507605
3MYLK4.40015839
4PHKG23.52935018
5PHKG13.52935018
6LMTK23.46127732
7PKN23.36918047
8PDK33.23085692
9PDK43.23085692
10DMPK2.92502638
11STK242.64409708
12BCKDK2.62313803
13PIK3CA2.52270386
14TRIB32.46398265
15MUSK2.35952606
16NEK12.22606407
17TIE12.14008743
18PDK21.87467366
19PINK11.74337711
20ZAK1.61157164
21STK38L1.45796731
22GRK71.39019236
23ILK1.36714470
24PAK31.33903552
25CDC42BPA1.24431585
26MARK11.22509350
27PRKD11.21687009
28CAMK2D1.19584320
29FLT31.12712849
30STK41.07319964
31MAP3K71.04164444
32ROCK11.03583978
33TRPM71.01802321
34MAPK120.96391414
35WNK40.95357644
36DAPK30.95011724
37MAPKAPK30.93884678
38MAP3K50.90029245
39MAP2K30.89649026
40MAP3K30.86356019
41PRKAA10.81786486
42INSRR0.81571652
43EEF2K0.81088921
44PRKAA20.80865131
45RIPK10.76751220
46PKN10.75631877
47CAMK40.71645712
48KDR0.70993022
49MAPK70.63078742
50CCNB10.60768639
51CAMK10.60390588
52PDGFRA0.59080955
53PTK2B0.58007275
54MAPK40.57923098
55RPS6KC10.56645606
56RPS6KL10.56645606
57ROCK20.55736445
58MOS0.55532680
59CAMK2A0.55470231
60STK380.54986921
61NME20.52338748
62DYRK1B0.50768375
63TGFBR20.50042066
64PRKACB0.49420097
65CAMK2B0.49249838
66WNK10.49020232
67RPS6KA60.47646179
68MAP2K10.47549109
69ERBB30.47130769
70MAP3K60.46695030
71KSR20.46626408
72NEK90.46623153
73EPHA30.46322601
74AKT20.43179087
75STK390.41012613
76PRKACA0.39094161
77PIK3CG0.38205594
78CAMK2G0.37158249
79PRKACG0.36655474
80NME10.36136637
81PRKCE0.34889318
82LIMK10.34786859
83MAP3K130.32499199
84RPS6KB20.27843031
85PTK60.27788434
86PRKD30.27097375
87PRKG20.26765305
88EPHB10.25500936
89PDPK10.25052763
90LATS10.24477422
91SIK10.23489434
92PRKG10.23412388
93RPS6KA10.23320989
94SGK20.22275184
95MAPK100.21982233
96EPHB20.21879193
97PDK10.21240959
98ICK0.20713671
99PRKCH0.20691235
100MARK30.18833699
101LRRK20.17946037
102MAP3K110.17452766
103MAP3K100.17419878
104MAPK110.17398954
105RAF10.16306854
106LATS20.16034228
107ARAF0.15069951
108MAP2K40.14541140
109JAK10.14250529
110MARK20.13775461
111ZAP700.13260559
112TBK10.12867838
113FER0.12788317
114NLK0.12187340
115SGK30.11826762
116STK110.11665053
117MAP3K10.11634564
118UHMK10.11490663
119MTOR0.10886400
120RET0.10817092
121FGFR40.10808375
122PRKCQ0.09978223
123MAPKAPK20.09792892
124RPS6KA30.09289344
125RPS6KB10.09205529
126SGK10.08891339
127MAP2K60.06864345

Predicted pathways (KEGG)

RankGene SetZ-score
1Citrate cycle (TCA cycle)_Homo sapiens_hsa000205.87830212
2Cardiac muscle contraction_Homo sapiens_hsa042604.49375900
32-Oxocarboxylic acid metabolism_Homo sapiens_hsa012104.28244277
4Dilated cardiomyopathy_Homo sapiens_hsa054143.63728463
5Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054103.60785950
6Parkinsons disease_Homo sapiens_hsa050123.42912299
7Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004003.32153780
8Oxidative phosphorylation_Homo sapiens_hsa001903.31920919
9Propanoate metabolism_Homo sapiens_hsa006403.27328454
10Fatty acid degradation_Homo sapiens_hsa000712.96421103
11Carbon metabolism_Homo sapiens_hsa012002.62278954
12Alzheimers disease_Homo sapiens_hsa050102.46731356
13Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.38635906
14Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa049322.29215291
15Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054122.26942684
16Fatty acid metabolism_Homo sapiens_hsa012122.19812405
17Huntingtons disease_Homo sapiens_hsa050162.16239407
18Pyruvate metabolism_Homo sapiens_hsa006201.91238427
19Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.80228538
20Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa042611.64269481
21Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.52352419
22Butanoate metabolism_Homo sapiens_hsa006501.47902440
23Viral myocarditis_Homo sapiens_hsa054161.47547382
24Fatty acid elongation_Homo sapiens_hsa000621.40171337
25Biosynthesis of amino acids_Homo sapiens_hsa012301.37814405
26Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.24253524
27Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.18846668
28Starch and sucrose metabolism_Homo sapiens_hsa005001.15269860
29PPAR signaling pathway_Homo sapiens_hsa033201.13269988
30Tryptophan metabolism_Homo sapiens_hsa003801.04551608
31Butirosin and neomycin biosynthesis_Homo sapiens_hsa005241.00028304
32Insulin resistance_Homo sapiens_hsa049310.95752444
33Arginine biosynthesis_Homo sapiens_hsa002200.95693467
34Glucagon signaling pathway_Homo sapiens_hsa049220.93710259
35cGMP-PKG signaling pathway_Homo sapiens_hsa040220.89306955
36beta-Alanine metabolism_Homo sapiens_hsa004100.84438324
37Adipocytokine signaling pathway_Homo sapiens_hsa049200.82816565
38Peroxisome_Homo sapiens_hsa041460.76602745
39Galactose metabolism_Homo sapiens_hsa000520.75256964
40Insulin signaling pathway_Homo sapiens_hsa049100.75031486
41Lysine degradation_Homo sapiens_hsa003100.72600873
42HIF-1 signaling pathway_Homo sapiens_hsa040660.72296093
43Phenylalanine metabolism_Homo sapiens_hsa003600.71963505
44Arginine and proline metabolism_Homo sapiens_hsa003300.66872119
45Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa049610.62795501
46GnRH signaling pathway_Homo sapiens_hsa049120.62328354
47Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.61408623
48Focal adhesion_Homo sapiens_hsa045100.60443839
49Longevity regulating pathway - multiple species_Homo sapiens_hsa042130.56087930
50Calcium signaling pathway_Homo sapiens_hsa040200.56040080
51Central carbon metabolism in cancer_Homo sapiens_hsa052300.55989510
52Fructose and mannose metabolism_Homo sapiens_hsa000510.55164875
53AMPK signaling pathway_Homo sapiens_hsa041520.54817384
54Tight junction_Homo sapiens_hsa045300.51307786
55Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.50170562
56Long-term potentiation_Homo sapiens_hsa047200.48094031
57Vascular smooth muscle contraction_Homo sapiens_hsa042700.47901083
58Pancreatic secretion_Homo sapiens_hsa049720.44159359
59Salivary secretion_Homo sapiens_hsa049700.43733153
60Oxytocin signaling pathway_Homo sapiens_hsa049210.43043015
61Cysteine and methionine metabolism_Homo sapiens_hsa002700.42388787
62Tyrosine metabolism_Homo sapiens_hsa003500.40380618
63Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.39788959
64Type II diabetes mellitus_Homo sapiens_hsa049300.39568119
65Fatty acid biosynthesis_Homo sapiens_hsa000610.37411038
66Metabolic pathways_Homo sapiens_hsa011000.36234006
67Cholinergic synapse_Homo sapiens_hsa047250.35155404
68Thyroid hormone signaling pathway_Homo sapiens_hsa049190.33019823
69ECM-receptor interaction_Homo sapiens_hsa045120.31300116
70Nitrogen metabolism_Homo sapiens_hsa009100.30489092
71Amphetamine addiction_Homo sapiens_hsa050310.28611532
72Regulation of autophagy_Homo sapiens_hsa041400.28049240
73Inflammatory mediator regulation of TRP channels_Homo sapiens_hsa047500.27327395
74Adherens junction_Homo sapiens_hsa045200.26617952
75MAPK signaling pathway_Homo sapiens_hsa040100.25540021
76cAMP signaling pathway_Homo sapiens_hsa040240.24193409
77Fat digestion and absorption_Homo sapiens_hsa049750.24109985
78Longevity regulating pathway - mammal_Homo sapiens_hsa042110.23357131
79Melanogenesis_Homo sapiens_hsa049160.21626250
80Regulation of lipolysis in adipocytes_Homo sapiens_hsa049230.21379573
81Primary bile acid biosynthesis_Homo sapiens_hsa001200.18544588
82Amoebiasis_Homo sapiens_hsa051460.18450836
83Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.18434721
84Renin secretion_Homo sapiens_hsa049240.18421636
85Bile secretion_Homo sapiens_hsa049760.16113627
86Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.15256874
87Leukocyte transendothelial migration_Homo sapiens_hsa046700.15043992
88Pentose phosphate pathway_Homo sapiens_hsa000300.14870426
89GABAergic synapse_Homo sapiens_hsa047270.11216973
90Insulin secretion_Homo sapiens_hsa049110.11163818
91Regulation of actin cytoskeleton_Homo sapiens_hsa048100.11082155
92Terpenoid backbone biosynthesis_Homo sapiens_hsa009000.09485505
93Protein digestion and absorption_Homo sapiens_hsa049740.09430706
94Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.09348481
95Carbohydrate digestion and absorption_Homo sapiens_hsa049730.08799258
96Gastric acid secretion_Homo sapiens_hsa049710.08377314
97Proteoglycans in cancer_Homo sapiens_hsa052050.08041008
98Circadian rhythm_Homo sapiens_hsa047100.07753316
99Sulfur relay system_Homo sapiens_hsa041220.07291679
100Endometrial cancer_Homo sapiens_hsa052130.07051076
101Caffeine metabolism_Homo sapiens_hsa002320.06185519
102Long-term depression_Homo sapiens_hsa047300.05829229
103Sulfur metabolism_Homo sapiens_hsa009200.03154385
104Platelet activation_Homo sapiens_hsa046110.03134071
105Ovarian steroidogenesis_Homo sapiens_hsa049130.02526528
106Glycerolipid metabolism_Homo sapiens_hsa005610.02455343
107Aldosterone synthesis and secretion_Homo sapiens_hsa049250.02327469
108Circadian entrainment_Homo sapiens_hsa047130.00638839
109Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964-0.0863113
110Ascorbate and aldarate metabolism_Homo sapiens_hsa00053-0.0857782
111Gap junction_Homo sapiens_hsa04540-0.0834456
112PI3K-Akt signaling pathway_Homo sapiens_hsa04151-0.0786277
113VEGF signaling pathway_Homo sapiens_hsa04370-0.0658198
114Toxoplasmosis_Homo sapiens_hsa05145-0.0621925
115Glutathione metabolism_Homo sapiens_hsa00480-0.0475977
116Small cell lung cancer_Homo sapiens_hsa05222-0.0462204
117FoxO signaling pathway_Homo sapiens_hsa04068-0.0376717
118mTOR signaling pathway_Homo sapiens_hsa04150-0.0280087
119ABC transporters_Homo sapiens_hsa02010-0.0071868
120Renal cell carcinoma_Homo sapiens_hsa05211-0.0004856

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