Rank | Gene Set | Z-score |
---|---|---|
1 | L-phenylalanine catabolic process (GO:0006559) | 6.73219083 |
2 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 6.73219083 |
3 | L-phenylalanine metabolic process (GO:0006558) | 6.45825212 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 6.45825212 |
5 | aromatic amino acid family catabolic process (GO:0009074) | 6.15708784 |
6 | indole-containing compound catabolic process (GO:0042436) | 5.66423203 |
7 | indolalkylamine catabolic process (GO:0046218) | 5.66423203 |
8 | tryptophan catabolic process (GO:0006569) | 5.66423203 |
9 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 5.55931581 |
10 | cysteine metabolic process (GO:0006534) | 5.50734727 |
11 | kynurenine metabolic process (GO:0070189) | 5.49105867 |
12 | tryptophan metabolic process (GO:0006568) | 5.39210841 |
13 | bile acid biosynthetic process (GO:0006699) | 5.28869709 |
14 | urea metabolic process (GO:0019627) | 5.21443972 |
15 | urea cycle (GO:0000050) | 5.21443972 |
16 | alpha-linolenic acid metabolic process (GO:0036109) | 5.18610613 |
17 | glyoxylate metabolic process (GO:0046487) | 5.17961216 |
18 | sulfur amino acid catabolic process (GO:0000098) | 5.08174860 |
19 | homocysteine metabolic process (GO:0050667) | 5.02970529 |
20 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.98364076 |
21 | protein carboxylation (GO:0018214) | 4.87764116 |
22 | peptidyl-glutamic acid carboxylation (GO:0017187) | 4.87764116 |
23 | high-density lipoprotein particle remodeling (GO:0034375) | 4.85082685 |
24 | lysine catabolic process (GO:0006554) | 4.79271985 |
25 | lysine metabolic process (GO:0006553) | 4.79271985 |
26 | serine family amino acid catabolic process (GO:0009071) | 4.78682339 |
27 | nitrogen cycle metabolic process (GO:0071941) | 4.75994664 |
28 | complement activation, alternative pathway (GO:0006957) | 4.73547675 |
29 | negative regulation of fibrinolysis (GO:0051918) | 4.65074863 |
30 | bile acid metabolic process (GO:0008206) | 4.62882649 |
31 | regulation of protein activation cascade (GO:2000257) | 4.59227900 |
32 | regulation of fibrinolysis (GO:0051917) | 4.48275427 |
33 | regulation of triglyceride catabolic process (GO:0010896) | 4.47481496 |
34 | aromatic amino acid family metabolic process (GO:0009072) | 4.46667853 |
35 | amino-acid betaine metabolic process (GO:0006577) | 4.45410711 |
36 | epoxygenase P450 pathway (GO:0019373) | 4.40768754 |
37 | reverse cholesterol transport (GO:0043691) | 4.35560673 |
38 | regulation of complement activation (GO:0030449) | 4.30414796 |
39 | negative regulation of protein activation cascade (GO:2000258) | 4.28628286 |
40 | triglyceride homeostasis (GO:0070328) | 4.25748775 |
41 | acylglycerol homeostasis (GO:0055090) | 4.25748775 |
42 | intestinal cholesterol absorption (GO:0030299) | 4.25275965 |
43 | alpha-amino acid catabolic process (GO:1901606) | 4.24167824 |
44 | negative regulation of cholesterol transport (GO:0032375) | 4.23316273 |
45 | negative regulation of sterol transport (GO:0032372) | 4.23316273 |
46 | phospholipid efflux (GO:0033700) | 4.20326404 |
47 | tyrosine metabolic process (GO:0006570) | 4.17139503 |
48 | plasma lipoprotein particle remodeling (GO:0034369) | 4.15191575 |
49 | protein-lipid complex remodeling (GO:0034368) | 4.15191575 |
50 | macromolecular complex remodeling (GO:0034367) | 4.15191575 |
51 | intestinal absorption (GO:0050892) | 4.14308128 |
52 | cellular modified amino acid catabolic process (GO:0042219) | 4.11882618 |
53 | bile acid and bile salt transport (GO:0015721) | 4.11049952 |
54 | low-density lipoprotein particle remodeling (GO:0034374) | 4.10574135 |
55 | drug transmembrane transport (GO:0006855) | 4.09140138 |
56 | indolalkylamine metabolic process (GO:0006586) | 4.05571528 |
57 | valine metabolic process (GO:0006573) | 4.04227698 |
58 | regulation of cholesterol esterification (GO:0010872) | 4.03255610 |
59 | serine family amino acid metabolic process (GO:0009069) | 4.02435183 |
60 | glycine metabolic process (GO:0006544) | 4.01999543 |
61 | drug catabolic process (GO:0042737) | 3.99044386 |
62 | cellular amino acid catabolic process (GO:0009063) | 3.95832898 |
63 | plasma lipoprotein particle clearance (GO:0034381) | 3.94107975 |
64 | ethanol oxidation (GO:0006069) | 3.92498609 |
65 | cellular glucuronidation (GO:0052695) | 3.88943144 |
66 | negative regulation of complement activation (GO:0045916) | 3.87512843 |
67 | coenzyme catabolic process (GO:0009109) | 3.85364505 |
68 | regulation of cholesterol homeostasis (GO:2000188) | 3.82598143 |
69 | glutamate metabolic process (GO:0006536) | 3.82069358 |
70 | benzene-containing compound metabolic process (GO:0042537) | 3.81784173 |
71 | cholesterol efflux (GO:0033344) | 3.80664126 |
72 | cellular biogenic amine catabolic process (GO:0042402) | 3.79402342 |
73 | amine catabolic process (GO:0009310) | 3.79402342 |
74 | plasma lipoprotein particle assembly (GO:0034377) | 3.77927693 |
75 | cellular ketone body metabolic process (GO:0046950) | 3.77712930 |
76 | urate metabolic process (GO:0046415) | 3.73437739 |
77 | phospholipid homeostasis (GO:0055091) | 3.73367089 |
78 | serine family amino acid biosynthetic process (GO:0009070) | 3.70214118 |
79 | imidazole-containing compound metabolic process (GO:0052803) | 3.68931917 |
80 | plasma lipoprotein particle organization (GO:0071827) | 3.67912371 |
81 | dicarboxylic acid biosynthetic process (GO:0043650) | 3.66230946 |
82 | regulation of bile acid biosynthetic process (GO:0070857) | 3.63124831 |
83 | short-chain fatty acid metabolic process (GO:0046459) | 3.62100490 |
84 | 2-oxoglutarate metabolic process (GO:0006103) | 3.57303224 |
85 | cholesterol homeostasis (GO:0042632) | 3.56105136 |
86 | positive regulation of triglyceride lipase activity (GO:0061365) | 3.54857591 |
87 | positive regulation of lipoprotein lipase activity (GO:0051006) | 3.54857591 |
88 | sterol homeostasis (GO:0055092) | 3.53135533 |
89 | organic acid catabolic process (GO:0016054) | 3.51846248 |
90 | carboxylic acid catabolic process (GO:0046395) | 3.51846248 |
91 | very-low-density lipoprotein particle assembly (GO:0034379) | 3.48171796 |
92 | fatty acid oxidation (GO:0019395) | 3.48034454 |
93 | positive regulation of lipid catabolic process (GO:0050996) | 3.47629452 |
94 | fatty acid beta-oxidation (GO:0006635) | 3.46890561 |
95 | purine ribonucleoside bisphosphate metabolic process (GO:0034035) | 3.46839730 |
96 | 3-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427) | 3.46839730 |
97 | protein-lipid complex assembly (GO:0065005) | 3.46260565 |
98 | lipoprotein metabolic process (GO:0042157) | 3.45155049 |
99 | negative regulation of humoral immune response (GO:0002921) | 3.43777625 |
100 | sulfation (GO:0051923) | 3.43334433 |
101 | acetyl-CoA metabolic process (GO:0006084) | 3.42598399 |
102 | blood coagulation, intrinsic pathway (GO:0007597) | 3.41970026 |
103 | lipid oxidation (GO:0034440) | 3.40876267 |
104 | negative regulation of lipase activity (GO:0060192) | 3.40745263 |
105 | glucuronate metabolic process (GO:0019585) | 3.40447544 |
106 | uronic acid metabolic process (GO:0006063) | 3.40447544 |
107 | drug transport (GO:0015893) | 3.37914396 |
108 | fibrinolysis (GO:0042730) | 3.37321052 |
109 | protein-lipid complex subunit organization (GO:0071825) | 3.37233895 |
110 | exogenous drug catabolic process (GO:0042738) | 3.35540686 |
111 | flavonoid metabolic process (GO:0009812) | 3.35111833 |
112 | monocarboxylic acid catabolic process (GO:0072329) | 3.32389817 |
113 | ethanol metabolic process (GO:0006067) | 3.27196100 |
114 | drug metabolic process (GO:0017144) | 3.20629916 |
115 | regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081) | 3.13172529 |
116 | water-soluble vitamin biosynthetic process (GO:0042364) | 3.00994384 |
117 | regulation of humoral immune response (GO:0002920) | 2.98420272 |
118 | diacylglycerol metabolic process (GO:0046339) | 2.94163235 |
119 | lipoprotein transport (GO:0042953) | 2.92842462 |
120 | omega-hydroxylase P450 pathway (GO:0097267) | 2.90595376 |
121 | cholesterol transport (GO:0030301) | 2.90307601 |
122 | sterol transport (GO:0015918) | 2.90307601 |
123 | phenylpropanoid metabolic process (GO:0009698) | 2.87882856 |
124 | cellular anion homeostasis (GO:0030002) | 2.81817192 |
125 | negative regulation of hemostasis (GO:1900047) | 2.79291895 |
126 | negative regulation of blood coagulation (GO:0030195) | 2.79291895 |
127 | positive regulation of glycolytic process (GO:0045821) | 2.79066099 |
128 | protein activation cascade (GO:0072376) | 2.78905310 |
129 | vitamin transmembrane transport (GO:0035461) | 2.78666078 |
130 | L-ascorbic acid metabolic process (GO:0019852) | 2.78346485 |
131 | positive regulation of fatty acid oxidation (GO:0046321) | 2.76400728 |
132 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 2.74689415 |
133 | vitamin biosynthetic process (GO:0009110) | 2.73320393 |
134 | acute-phase response (GO:0006953) | 2.67405894 |
135 | transepithelial transport (GO:0070633) | 2.65484815 |
136 | lipid homeostasis (GO:0055088) | 2.64487210 |
137 | negative regulation of coagulation (GO:0050819) | 2.64394876 |
138 | polyketide metabolic process (GO:0030638) | 2.63949732 |
139 | doxorubicin metabolic process (GO:0044598) | 2.63949732 |
140 | daunorubicin metabolic process (GO:0044597) | 2.63949732 |
141 | primary alcohol catabolic process (GO:0034310) | 2.62804477 |
142 | angiotensin maturation (GO:0002003) | 2.62006587 |
143 | primary alcohol metabolic process (GO:0034308) | 2.60501548 |
144 | oxidative demethylation (GO:0070989) | 2.59649961 |
Rank | Gene Set | Z-score |
---|---|---|
1 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 7.55320501 |
2 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 6.64510551 |
3 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 6.02883649 |
4 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 6.02110983 |
5 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 4.56845389 |
6 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 4.31463079 |
7 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 4.18975563 |
8 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 3.88599277 |
9 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 3.43573292 |
10 | GATA1_22025678_ChIP-Seq_K562_Human | 2.36756463 |
11 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.14092716 |
12 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 2.02338719 |
13 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 2.01948345 |
14 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 10.3234605 |
15 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.98087765 |
16 | * STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.92118654 |
17 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.90473375 |
18 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 1.88470305 |
19 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.83286627 |
20 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 1.77371335 |
21 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 1.76194345 |
22 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.74176713 |
23 | * FOXA2_19822575_ChIP-Seq_HepG2_Human | 1.71487671 |
24 | VDR_22108803_ChIP-Seq_LS180_Human | 1.71435268 |
25 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.69855621 |
26 | GBX2_23144817_ChIP-Seq_PC3_Human | 1.66476408 |
27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.65722834 |
28 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.62731391 |
29 | * ZNF274_21170338_ChIP-Seq_K562_Hela | 1.58284463 |
30 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.56071557 |
31 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.54350969 |
32 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.53076537 |
33 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 1.52826197 |
34 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.52636066 |
35 | IGF1R_20145208_ChIP-Seq_DFB_Human | 1.51861126 |
36 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 1.49649785 |
37 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.49577097 |
38 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.48980206 |
39 | BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse | 1.47220027 |
40 | * HNF4A_19822575_ChIP-Seq_HepG2_Human | 1.45914366 |
41 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.43632494 |
42 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.36950118 |
43 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.36643943 |
44 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.36094475 |
45 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.35133009 |
46 | * STAT3_23295773_ChIP-Seq_U87_Human | 1.34806436 |
47 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.34355582 |
48 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.33105395 |
49 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 1.30995288 |
50 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.30743625 |
51 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.30743625 |
52 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.29629045 |
53 | * CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse | 1.29137456 |
54 | * SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 1.29003414 |
55 | CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human | 1.27957440 |
56 | * Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse | 1.24665487 |
57 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.24049152 |
58 | TCF4_23295773_ChIP-Seq_U87_Human | 1.23376329 |
59 | TP53_16413492_ChIP-PET_HCT116_Human | 1.23284760 |
60 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.20892973 |
61 | NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 1.17806603 |
62 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.17697675 |
63 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.17247632 |
64 | CRX_20693478_ChIP-Seq_RETINA_Mouse | 1.16473250 |
65 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 1.15573790 |
66 | FOXA1_21572438_ChIP-Seq_LNCaP_Human | 1.15326980 |
67 | IRF8_21731497_ChIP-ChIP_J774_Mouse | 1.15111608 |
68 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.13991561 |
69 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.13761508 |
70 | P300_19829295_ChIP-Seq_ESCs_Human | 1.13489164 |
71 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.12980208 |
72 | TAF15_26573619_Chip-Seq_HEK293_Human | 1.12813760 |
73 | EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse | 1.12710683 |
74 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.11277509 |
75 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.10781998 |
76 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.10646429 |
77 | STAT3_18555785_Chip-Seq_ESCs_Mouse | 1.10455666 |
78 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.10240074 |
79 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.10240074 |
80 | SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse | 1.10182624 |
81 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.09973959 |
82 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.09727310 |
83 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.09727310 |
84 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.09719041 |
85 | TP63_23658742_ChIP-Seq_EP156T_Human | 1.09614268 |
86 | NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.08297158 |
87 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 1.08257336 |
88 | * SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse | 1.07772644 |
89 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.07743755 |
90 | P53_22387025_ChIP-Seq_ESCs_Mouse | 1.07116963 |
91 | TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse | 1.05414142 |
92 | OCT4_21477851_ChIP-Seq_ESCs_Mouse | 1.04976208 |
93 | NANOG_18555785_Chip-Seq_ESCs_Mouse | 1.04846409 |
94 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.04830393 |
95 | AR_25329375_ChIP-Seq_VCAP_Human | 1.04476664 |
96 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.03660254 |
97 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.02437649 |
98 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.02378534 |
99 | OCT4_18555785_Chip-Seq_ESCs_Mouse | 1.02155180 |
100 | AR_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.99356198 |
101 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.98917812 |
102 | HTT_18923047_ChIP-ChIP_STHdh_Human | 0.98628974 |
103 | * BRD4_27068464_Chip-Seq_AML-cells_Mouse | 0.94149129 |
104 | * IRF8_27001747_Chip-Seq_BMDM_Mouse | 0.92821054 |
105 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 0.92682453 |
106 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.91532964 |
107 | FOXA1_26743006_Chip-Seq_LNCaP-abl_Human | 0.89894366 |
108 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 0.89856628 |
109 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 0.88732702 |
110 | FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human | 0.85259020 |
111 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 0.84387390 |
112 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 0.84256574 |
113 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 0.82177658 |
114 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.82138127 |
115 | FOXA1_25552417_ChIP-Seq_VCAP_Human | 0.79179867 |
116 | FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.76378144 |
117 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 0.76167781 |
118 | STAT6_20620947_ChIP-Seq_CD4_POS_T_Human | 0.75277783 |
119 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 0.74687626 |
120 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.74406234 |
121 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 0.72610255 |
122 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.71395720 |
123 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.71249962 |
124 | GATA2_19941826_ChIP-Seq_K562_Human | 0.70389734 |
125 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.68876092 |
126 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.66127408 |
127 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.65949984 |
128 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 0.65248608 |
129 | GATA3_24758297_ChIP-Seq_MCF-7_Human | 0.64183710 |
130 | RARA_24833708_ChIP-Seq_LIVER_Mouse | 0.63835462 |
131 | FOXP3_17237761_ChIP-ChIP_TREG_Mouse | 0.63730222 |
132 | GATA1_19941826_ChIP-Seq_K562_Human | 0.63263472 |
133 | CEBPB_22108803_ChIP-Seq_LS180_Human | 0.62719971 |
134 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.61676263 |
135 | RUNX_20019798_ChIP-Seq_JUKART_Human | 0.61641083 |
136 | * MYB_26560356_Chip-Seq_TH1_Human | 0.60813136 |
137 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 0.60630030 |
138 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.60533665 |
139 | KAP1_22055183_ChIP-Seq_ESCs_Mouse | 0.60097148 |
140 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.59945404 |
141 | PPARG_20887899_ChIP-Seq_3T3-L1_Mouse | 0.59943242 |
142 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 0.59814368 |
143 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.59002693 |
144 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.58921940 |
145 | GATA2_21666600_ChIP-Seq_HMVEC_Human | 0.58745043 |
146 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.58374020 |
147 | ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human | 0.57629175 |
148 | EGR1_19032775_ChIP-ChIP_M12_Human | 0.56733300 |
149 | SCL_19346495_ChIP-Seq_HPC-7_Human | 0.56674387 |
150 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.56376038 |
151 | RACK7_27058665_Chip-Seq_MCF-7_Human | 0.56217424 |
152 | STAT3_20064451_ChIP-Seq_CD4+T_Mouse | 0.55463733 |
153 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.55131640 |
154 | E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human | 0.54768019 |
155 | * PU_27001747_Chip-Seq_BMDM_Mouse | 0.54151947 |
156 | AR_20517297_ChIP-Seq_VCAP_Human | 0.54145421 |
157 | FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse | 0.54079167 |
158 | * TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.53515114 |
159 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 0.52969001 |
160 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.52816310 |
161 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.52134519 |
162 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.52134519 |
163 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 0.52031954 |
164 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.50957052 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 7.38527390 |
2 | MP0005360_urolithiasis | 6.95091478 |
3 | MP0005365_abnormal_bile_salt | 5.78053667 |
4 | MP0005085_abnormal_gallbladder_physiolo | 5.77328429 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 4.47541778 |
6 | MP0003252_abnormal_bile_duct | 3.96733360 |
7 | MP0003806_abnormal_nucleotide_metabolis | 3.16077660 |
8 | MP0010329_abnormal_lipoprotein_level | 3.11540328 |
9 | MP0001666_abnormal_nutrient_absorption | 3.02028864 |
10 | MP0005083_abnormal_biliary_tract | 2.95318001 |
11 | MP0009840_abnormal_foam_cell | 2.81162442 |
12 | MP0003183_abnormal_peptide_metabolism | 2.60098001 |
13 | MP0003195_calcinosis | 2.57425908 |
14 | MP0005332_abnormal_amino_acid | 2.57323950 |
15 | MP0002138_abnormal_hepatobiliary_system | 2.40022569 |
16 | MP0004019_abnormal_vitamin_homeostasis | 2.25654570 |
17 | MP0003191_abnormal_cellular_cholesterol | 2.17152628 |
18 | MP0000609_abnormal_liver_physiology | 2.13425626 |
19 | MP0003868_abnormal_feces_composition | 1.99923185 |
20 | MP0002118_abnormal_lipid_homeostasis | 1.93609960 |
21 | MP0009780_abnormal_chondrocyte_physiolo | 1.88218918 |
22 | MP0005319_abnormal_enzyme/_coenzyme | 1.72888554 |
23 | MP0005379_endocrine/exocrine_gland_phen | 1.59970571 |
24 | MP0009643_abnormal_urine_homeostasis | 1.59251614 |
25 | MP0002132_abnormal_respiratory_system | 1.55170732 |
26 | MP0001764_abnormal_homeostasis | 1.42780130 |
27 | MP0003300_gastrointestinal_ulcer | 1.38067614 |
28 | MP0003646_muscle_fatigue | 1.34916440 |
29 | MP0005451_abnormal_body_composition | 1.34135651 |
30 | MP0003705_abnormal_hypodermis_morpholog | 1.32126146 |
31 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.31171617 |
32 | MP0005220_abnormal_exocrine_pancreas | 1.30330677 |
33 | MP0002160_abnormal_reproductive_system | 1.26906787 |
34 | MP0003122_maternal_imprinting | 1.24611553 |
35 | MP0008872_abnormal_physiological_respon | 1.22273135 |
36 | MP0000598_abnormal_liver_morphology | 1.18729425 |
37 | MP0002837_dystrophic_cardiac_calcinosis | 1.16414816 |
38 | MP0009764_decreased_sensitivity_to | 1.13111380 |
39 | MP0002254_reproductive_system_inflammat | 1.12746217 |
40 | MP0005670_abnormal_white_adipose | 1.12668184 |
41 | MP0003186_abnormal_redox_activity | 1.11568645 |
42 | MP0005636_abnormal_mineral_homeostasis | 1.08744282 |
43 | MP0004264_abnormal_extraembryonic_tissu | 1.07183036 |
44 | MP0002163_abnormal_gland_morphology | 1.06199344 |
45 | MP0003656_abnormal_erythrocyte_physiolo | 1.03450435 |
46 | MP0009785_altered_susceptibility_to | 1.02789714 |
47 | MP0005647_abnormal_sex_gland | 1.02576804 |
48 | MP0005389_reproductive_system_phenotype | 1.01420489 |
49 | MP0003011_delayed_dark_adaptation | 1.00895458 |
50 | MP0008469_abnormal_protein_level | 1.00621848 |
51 | MP0001986_abnormal_taste_sensitivity | 0.99288851 |
52 | MP0003879_abnormal_hair_cell | 0.98565759 |
53 | MP0009763_increased_sensitivity_to | 0.97121288 |
54 | MP0004145_abnormal_muscle_electrophysio | 0.96418242 |
55 | MP0009697_abnormal_copulation | 0.95702448 |
56 | MP0005646_abnormal_pituitary_gland | 0.95087002 |
57 | MP0004134_abnormal_chest_morphology | 0.95014673 |
58 | MP0003866_abnormal_defecation | 0.92935374 |
59 | MP0005551_abnormal_eye_electrophysiolog | 0.92723333 |
60 | MP0003172_abnormal_lysosome_physiology | 0.90970074 |
61 | MP0005410_abnormal_fertilization | 0.90875796 |
62 | MP0003718_maternal_effect | 0.90486310 |
63 | MP0002078_abnormal_glucose_homeostasis | 0.90440075 |
64 | MP0000685_abnormal_immune_system | 0.87359162 |
65 | MP0009642_abnormal_blood_homeostasis | 0.87224392 |
66 | MP0002928_abnormal_bile_duct | 0.85376789 |
67 | MP0002277_abnormal_respiratory_mucosa | 0.84964590 |
68 | MP0005408_hypopigmentation | 0.84935391 |
69 | MP0001756_abnormal_urination | 0.84582920 |
70 | MP0000013_abnormal_adipose_tissue | 0.84236725 |
71 | MP0003950_abnormal_plasma_membrane | 0.84202148 |
72 | MP0005084_abnormal_gallbladder_morpholo | 0.83928156 |
73 | MP0003436_decreased_susceptibility_to | 0.83297042 |
74 | MP0002909_abnormal_adrenal_gland | 0.83170889 |
75 | MP0005334_abnormal_fat_pad | 0.82576072 |
76 | MP0004043_abnormal_pH_regulation | 0.82144002 |
77 | MP0002136_abnormal_kidney_physiology | 0.80896945 |
78 | MP0002971_abnormal_brown_adipose | 0.80362990 |
79 | MP0010234_abnormal_vibrissa_follicle | 0.77788841 |
80 | MP0009765_abnormal_xenobiotic_induced | 0.77421697 |
81 | MP0005058_abnormal_lysosome_morphology | 0.77396898 |
82 | MP0005666_abnormal_adipose_tissue | 0.76914466 |
83 | MP0001790_abnormal_immune_system | 0.76094833 |
84 | MP0005387_immune_system_phenotype | 0.76094833 |
85 | MP0010678_abnormal_skin_adnexa | 0.75271896 |
86 | MP0000427_abnormal_hair_cycle | 0.73952193 |
87 | MP0004484_altered_response_of | 0.73794637 |
88 | MP0004130_abnormal_muscle_cell | 0.73769724 |
89 | MP0008877_abnormal_DNA_methylation | 0.73347854 |
90 | MP0005464_abnormal_platelet_physiology | 0.72277567 |
91 | MP0005310_abnormal_salivary_gland | 0.70953676 |
92 | MP0001661_extended_life_span | 0.70477238 |
93 | MP0004142_abnormal_muscle_tone | 0.68640093 |
94 | MP0000604_amyloidosis | 0.67784258 |
95 | MP0000383_abnormal_hair_follicle | 0.67574423 |
96 | MP0001800_abnormal_humoral_immune | 0.65501672 |
97 | MP0001485_abnormal_pinna_reflex | 0.64980736 |
98 | MP0002876_abnormal_thyroid_physiology | 0.63640886 |
99 | MP0001845_abnormal_inflammatory_respons | 0.63534518 |
100 | MP0001765_abnormal_ion_homeostasis | 0.63345738 |
101 | MP0005164_abnormal_response_to | 0.62868105 |
102 | MP0003724_increased_susceptibility_to | 0.62609083 |
103 | MP0006036_abnormal_mitochondrial_physio | 0.62332865 |
104 | MP0001664_abnormal_digestion | 0.61819914 |
105 | MP0000569_abnormal_digit_pigmentation | 0.61223292 |
106 | MP0005025_abnormal_response_to | 0.61185738 |
107 | MP0004185_abnormal_adipocyte_glucose | 0.61177639 |
108 | MP0001944_abnormal_pancreas_morphology | 0.60463991 |
109 | MP0004947_skin_inflammation | 0.59023513 |
110 | MP0009053_abnormal_anal_canal | 0.58741557 |
111 | MP0005535_abnormal_body_temperature | 0.58626216 |
112 | MP0010368_abnormal_lymphatic_system | 0.58182994 |
113 | MP0002166_altered_tumor_susceptibility | 0.57811307 |
114 | MP0005376_homeostasis/metabolism_phenot | 0.56729083 |
115 | MP0001881_abnormal_mammary_gland | 0.56672853 |
116 | MP0004782_abnormal_surfactant_physiolog | 0.56082612 |
117 | MP0006082_CNS_inflammation | 0.55679421 |
118 | MP0005448_abnormal_energy_balance | 0.55557356 |
119 | MP0001853_heart_inflammation | 0.55516177 |
120 | MP0009384_cardiac_valve_regurgitation | 0.53490523 |
121 | MP0002693_abnormal_pancreas_physiology | 0.52943089 |
122 | MP0010155_abnormal_intestine_physiology | 0.51652477 |
123 | MP0001873_stomach_inflammation | 0.49263716 |
124 | MP0009115_abnormal_fat_cell | 0.49109568 |
125 | MP0002796_impaired_skin_barrier | 0.48906482 |
126 | MP0002168_other_aberrant_phenotype | 0.47974366 |
127 | MP0003453_abnormal_keratinocyte_physiol | 0.47373104 |
128 | MP0005248_abnormal_Harderian_gland | 0.47339837 |
129 | MP0003953_abnormal_hormone_level | 0.47213051 |
130 | MP0000639_abnormal_adrenal_gland | 0.46361325 |
131 | MP0005395_other_phenotype | 0.45726880 |
132 | MP0003638_abnormal_response/metabolism_ | 0.44833481 |
133 | MP0002060_abnormal_skin_morphology | 0.44072962 |
134 | MP0009672_abnormal_birth_weight | 0.43141586 |
135 | MP0000579_abnormal_nail_morphology | 0.42803765 |
136 | MP0003959_abnormal_lean_body | 0.40865029 |
137 | MP0008961_abnormal_basal_metabolism | 0.40809821 |
138 | MP0002970_abnormal_white_adipose | 0.40781252 |
139 | MP0004381_abnormal_hair_follicle | 0.40768100 |
140 | MP0001835_abnormal_antigen_presentation | 0.40373090 |
141 | MP0005266_abnormal_metabolism | 0.39260424 |
142 | MP0003303_peritoneal_inflammation | 0.39150960 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Intrahepatic cholestasis (HP:0001406) | 6.82011337 |
2 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 6.34602019 |
3 | Deep venous thrombosis (HP:0002625) | 6.23579007 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 5.95491987 |
5 | Xanthomatosis (HP:0000991) | 5.60576682 |
6 | Hypobetalipoproteinemia (HP:0003563) | 5.38955526 |
7 | Prolonged partial thromboplastin time (HP:0003645) | 5.37429126 |
8 | Complement deficiency (HP:0004431) | 4.71436152 |
9 | Hyperlipoproteinemia (HP:0010980) | 4.49751841 |
10 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 4.36158458 |
11 | Hypoglycemic coma (HP:0001325) | 4.31886285 |
12 | Joint hemorrhage (HP:0005261) | 4.30534371 |
13 | Abnormality of the common coagulation pathway (HP:0010990) | 4.25651293 |
14 | Ketosis (HP:0001946) | 4.23890999 |
15 | Fat malabsorption (HP:0002630) | 4.21642883 |
16 | Hypolipoproteinemia (HP:0010981) | 4.18312536 |
17 | Hyperammonemia (HP:0001987) | 4.18122361 |
18 | Epidermoid cyst (HP:0200040) | 4.14780938 |
19 | Hyperglycinuria (HP:0003108) | 4.14719193 |
20 | Hyperglycinemia (HP:0002154) | 4.09891781 |
21 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 4.09856829 |
22 | Abnormality of glycine metabolism (HP:0010895) | 3.88228528 |
23 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.88228528 |
24 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 3.86857547 |
25 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 3.83154708 |
26 | Conjugated hyperbilirubinemia (HP:0002908) | 3.81093557 |
27 | Abnormality of the intrinsic pathway (HP:0010989) | 3.75484629 |
28 | Hypoalphalipoproteinemia (HP:0003233) | 3.75219354 |
29 | Abnormality of methionine metabolism (HP:0010901) | 3.65393778 |
30 | Abnormality of complement system (HP:0005339) | 3.47267554 |
31 | Ketoacidosis (HP:0001993) | 3.47100421 |
32 | Abnormality of purine metabolism (HP:0004352) | 3.31282004 |
33 | Abnormality of nucleobase metabolism (HP:0010932) | 3.31190985 |
34 | Abnormality of pyrimidine metabolism (HP:0004353) | 3.31008947 |
35 | Myocardial infarction (HP:0001658) | 3.22172876 |
36 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.21365112 |
37 | Hypercholesterolemia (HP:0003124) | 3.19959199 |
38 | Hypoglycemic seizures (HP:0002173) | 3.07615554 |
39 | Steatorrhea (HP:0002570) | 3.06847949 |
40 | Gout (HP:0001997) | 3.05798665 |
41 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 3.04161036 |
42 | Hyperbilirubinemia (HP:0002904) | 3.02985325 |
43 | Hepatocellular carcinoma (HP:0001402) | 2.85304053 |
44 | Abnormality of serum amino acid levels (HP:0003112) | 2.76137465 |
45 | Abnormality of the nasal septum (HP:0000419) | 2.75434945 |
46 | Abnormality of vitamin metabolism (HP:0100508) | 2.74865878 |
47 | Vascular calcification (HP:0004934) | 2.74009697 |
48 | Abnormality of vitamin B metabolism (HP:0004340) | 2.73026755 |
49 | Abnormality of the renal cortex (HP:0011035) | 2.70303249 |
50 | Skin nodule (HP:0200036) | 2.68503531 |
51 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 2.68422043 |
52 | Absent/shortened dynein arms (HP:0200106) | 2.68422043 |
53 | Metabolic acidosis (HP:0001942) | 2.67979181 |
54 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.66686246 |
55 | Systemic lupus erythematosus (HP:0002725) | 2.65713820 |
56 | Hypochromic microcytic anemia (HP:0004840) | 2.62384208 |
57 | Acanthocytosis (HP:0001927) | 2.57939835 |
58 | Esophageal varix (HP:0002040) | 2.52537395 |
59 | Pigmentary retinal degeneration (HP:0001146) | 2.52502726 |
60 | Generalized aminoaciduria (HP:0002909) | 2.52069958 |
61 | Hypothermia (HP:0002045) | 2.47771754 |
62 | Delayed CNS myelination (HP:0002188) | 2.46056862 |
63 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 2.43866977 |
64 | Dicarboxylic aciduria (HP:0003215) | 2.43866977 |
65 | Cardiovascular calcification (HP:0011915) | 2.42910768 |
66 | Decreased circulating renin level (HP:0003351) | 2.41252536 |
67 | Late onset (HP:0003584) | 2.40363261 |
68 | Pancreatitis (HP:0001733) | 2.40200053 |
69 | Malnutrition (HP:0004395) | 2.38940912 |
70 | Abnormality of the vitamin B12 metabolism (HP:0004341) | 2.37994706 |
71 | Recurrent gram-negative bacterial infections (HP:0005420) | 2.37624696 |
72 | Pancreatic cysts (HP:0001737) | 2.37469894 |
73 | Hydroxyprolinuria (HP:0003080) | 2.37421396 |
74 | Abnormality of proline metabolism (HP:0010907) | 2.37421396 |
75 | Hyperglycemia (HP:0003074) | 2.34636143 |
76 | Gingival bleeding (HP:0000225) | 2.34513705 |
77 | Symptomatic seizures (HP:0011145) | 2.33768995 |
78 | Confusion (HP:0001289) | 2.31683831 |
79 | Decreased central vision (HP:0007663) | 2.31147101 |
80 | Fair hair (HP:0002286) | 2.30630639 |
81 | Hypophosphatemic rickets (HP:0004912) | 2.30543650 |
82 | Glomerulonephritis (HP:0000099) | 2.30371702 |
83 | Menorrhagia (HP:0000132) | 2.25373432 |
84 | Abnormal respiratory epithelium morphology (HP:0012253) | 2.24988759 |
85 | Abnormal respiratory motile cilium morphology (HP:0005938) | 2.24988759 |
86 | Sensorimotor neuropathy (HP:0007141) | 2.23493627 |
87 | Abnormal ciliary motility (HP:0012262) | 2.22419765 |
88 | Hyperuricemia (HP:0002149) | 2.21620728 |
89 | Increased purine levels (HP:0004368) | 2.21620728 |
90 | Proximal tubulopathy (HP:0000114) | 2.21286391 |
91 | Chronic diarrhea (HP:0002028) | 2.20698534 |
92 | Congenital sensorineural hearing impairment (HP:0008527) | 2.20641884 |
93 | Mitral stenosis (HP:0001718) | 2.20599334 |
94 | Spontaneous abortion (HP:0005268) | 2.20263044 |
95 | Pancreatic fibrosis (HP:0100732) | 2.19543992 |
96 | Lethargy (HP:0001254) | 2.16848991 |
97 | Osteomalacia (HP:0002749) | 2.16564429 |
98 | Spastic diplegia (HP:0001264) | 2.15050628 |
99 | Pancreatic islet-cell hyperplasia (HP:0004510) | 2.13969152 |
100 | True hermaphroditism (HP:0010459) | 2.12625653 |
101 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.12165627 |
102 | Abnormal enzyme/coenzyme activity (HP:0012379) | 2.11673996 |
103 | Irritability (HP:0000737) | 2.09606476 |
104 | Renal cortical cysts (HP:0000803) | 2.07436797 |
105 | Alkalosis (HP:0001948) | 2.07207432 |
106 | Potter facies (HP:0002009) | 2.03951127 |
107 | Facial shape deformation (HP:0011334) | 2.03951127 |
108 | Abolished electroretinogram (ERG) (HP:0000550) | 2.02967640 |
109 | Abnormal gallbladder morphology (HP:0012437) | 2.01642232 |
110 | Abnormal respiratory motile cilium physiology (HP:0012261) | 2.01604988 |
111 | Thrombophlebitis (HP:0004418) | 1.98657030 |
112 | Genetic anticipation (HP:0003743) | 1.98030170 |
113 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.95130454 |
114 | Neonatal onset (HP:0003623) | 1.94866124 |
115 | Methylmalonic acidemia (HP:0002912) | 1.94787844 |
116 | Rhinitis (HP:0012384) | 1.94456314 |
117 | Enlarged kidneys (HP:0000105) | 1.93897637 |
118 | Cholelithiasis (HP:0001081) | 1.91834275 |
119 | Furrowed tongue (HP:0000221) | 1.90802279 |
120 | Poikilocytosis (HP:0004447) | 1.90115854 |
121 | Hemorrhage of the eye (HP:0011885) | 1.89971946 |
122 | Abnormality of alkaline phosphatase activity (HP:0004379) | 1.89877244 |
123 | Elevated alkaline phosphatase (HP:0003155) | 1.89770759 |
124 | Hyperkalemia (HP:0002153) | 1.89134533 |
125 | Rickets (HP:0002748) | 1.88985235 |
126 | Azoospermia (HP:0000027) | 1.87966278 |
127 | Abnormal cartilage morphology (HP:0002763) | 1.86214805 |
128 | Amyloidosis (HP:0011034) | 1.84096740 |
129 | Nephritis (HP:0000123) | 1.83219491 |
130 | Elevated hepatic transaminases (HP:0002910) | 1.82398246 |
131 | Cystic liver disease (HP:0006706) | 1.82387816 |
132 | Arthropathy (HP:0003040) | 1.81788290 |
133 | Acute hepatic failure (HP:0006554) | 1.80578893 |
134 | Vomiting (HP:0002013) | 1.80351265 |
135 | Glycosuria (HP:0003076) | 1.80245416 |
136 | Abnormality of urine glucose concentration (HP:0011016) | 1.80245416 |
137 | Abnormality of iron homeostasis (HP:0011031) | 1.79450190 |
138 | Chronic hepatic failure (HP:0100626) | 1.77889148 |
139 | Progressive cerebellar ataxia (HP:0002073) | 1.74278912 |
140 | Methylmalonic aciduria (HP:0012120) | 1.74019908 |
141 | Generalized hypopigmentation of hair (HP:0011358) | 1.73953080 |
142 | Recurrent sinusitis (HP:0011108) | 1.72190177 |
143 | Joint swelling (HP:0001386) | 1.71279430 |
144 | Bronchiectasis (HP:0002110) | 1.69882274 |
145 | Hyperactive renin-angiotensin system (HP:0000841) | 1.68042987 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 4.39486617 |
2 | ERN1 | 4.06593493 |
3 | TAOK3 | 3.98226007 |
4 | ACVR1B | 3.90529530 |
5 | INSRR | 3.45281889 |
6 | SIK1 | 3.29987946 |
7 | FGFR4 | 3.22497642 |
8 | MST4 | 2.58057246 |
9 | FRK | 2.49445494 |
10 | LATS1 | 2.40493143 |
11 | PKN2 | 2.36263455 |
12 | TRIB3 | 2.23539420 |
13 | OBSCN | 2.11396959 |
14 | MAP4K2 | 2.04547442 |
15 | PIK3CA | 2.04510998 |
16 | STK39 | 2.02470630 |
17 | MAP3K12 | 1.98881934 |
18 | IRAK3 | 1.96032472 |
19 | FLT3 | 1.91549744 |
20 | ADRBK2 | 1.90646983 |
21 | BMPR1B | 1.89016208 |
22 | MST1R | 1.87293360 |
23 | PTK6 | 1.82230779 |
24 | TYK2 | 1.70567417 |
25 | PIK3CG | 1.57685919 |
26 | ERBB4 | 1.56070569 |
27 | NEK9 | 1.51148566 |
28 | OXSR1 | 1.46750415 |
29 | MAPK11 | 1.45188176 |
30 | JAK1 | 1.41496907 |
31 | TGFBR2 | 1.39227525 |
32 | MAP2K6 | 1.38031675 |
33 | CDK12 | 1.36466885 |
34 | PINK1 | 1.36043961 |
35 | MAPKAPK3 | 1.35579715 |
36 | MAP3K14 | 1.34336171 |
37 | CAMK1D | 1.33465348 |
38 | MAP4K1 | 1.32526227 |
39 | STK38L | 1.30571190 |
40 | JAK2 | 1.29551489 |
41 | MAP3K10 | 1.27280671 |
42 | PHKG2 | 1.25261539 |
43 | PHKG1 | 1.25261539 |
44 | MAP3K7 | 1.22402710 |
45 | PRKAA2 | 1.19286222 |
46 | FER | 1.19078093 |
47 | WNK3 | 1.17868330 |
48 | STK10 | 1.16593549 |
49 | FGFR3 | 1.15985094 |
50 | GRK6 | 1.14995935 |
51 | MAP2K3 | 1.14837624 |
52 | CSK | 1.12552949 |
53 | EIF2AK3 | 1.11241807 |
54 | STK24 | 1.11188616 |
55 | TRPM7 | 1.11018793 |
56 | MAP3K3 | 1.09872556 |
57 | EPHB1 | 1.08124952 |
58 | NUAK1 | 1.06178591 |
59 | CDK6 | 1.04508671 |
60 | STK3 | 1.03228762 |
61 | JAK3 | 1.02860984 |
62 | TBK1 | 1.00794965 |
63 | ZAP70 | 0.99778803 |
64 | RIPK1 | 0.91016874 |
65 | EPHA3 | 0.86508674 |
66 | ITK | 0.86367616 |
67 | MAPK15 | 0.86141475 |
68 | PAK3 | 0.85003831 |
69 | CAMKK2 | 0.84978353 |
70 | BRSK2 | 0.84551797 |
71 | BMPR2 | 0.80450292 |
72 | SGK3 | 0.79945353 |
73 | WNK1 | 0.76189431 |
74 | PDK2 | 0.75983616 |
75 | CAMK1G | 0.75660779 |
76 | TXK | 0.75435016 |
77 | GSK3A | 0.74164989 |
78 | PRKAA1 | 0.70566635 |
79 | CSF1R | 0.68832235 |
80 | ERBB3 | 0.68760244 |
81 | NLK | 0.68242582 |
82 | IKBKE | 0.68182055 |
83 | DYRK1B | 0.67793908 |
84 | CDK4 | 0.67671242 |
85 | EPHA2 | 0.67101467 |
86 | FGFR2 | 0.66713710 |
87 | MAP2K4 | 0.65672588 |
88 | TLK1 | 0.64543356 |
89 | WNK4 | 0.64193810 |
90 | PTK2 | 0.63914168 |
91 | SGK1 | 0.62197176 |
92 | MTOR | 0.61662814 |
93 | MATK | 0.59458232 |
94 | MUSK | 0.59374138 |
95 | MET | 0.59148431 |
96 | LRRK2 | 0.59007886 |
97 | SYK | 0.57918538 |
98 | ERBB2 | 0.57537242 |
99 | PTK2B | 0.57064130 |
100 | IRAK1 | 0.55843204 |
101 | MAP2K2 | 0.55718373 |
102 | EEF2K | 0.55497244 |
103 | PRKCE | 0.54968279 |
104 | BTK | 0.54966808 |
105 | PDGFRA | 0.54681291 |
106 | CHUK | 0.54409952 |
107 | IRAK4 | 0.53676671 |
108 | TEC | 0.52659587 |
109 | LCK | 0.52051096 |
110 | LYN | 0.51487422 |
111 | KDR | 0.49374268 |
112 | PRKCQ | 0.48061797 |
113 | RPS6KB1 | 0.47185002 |
114 | IGF1R | 0.45130522 |
115 | MAPK4 | 0.44590489 |
116 | PRKACG | 0.44130968 |
117 | PIM1 | 0.43151297 |
118 | HIPK2 | 0.42872382 |
119 | GRK1 | 0.41577931 |
120 | MAP3K4 | 0.41182607 |
121 | SGK2 | 0.41146578 |
122 | PRKG2 | 0.41052014 |
123 | ZAK | 0.40996362 |
124 | KIT | 0.40908041 |
125 | MAP3K2 | 0.40869544 |
126 | ABL2 | 0.40867679 |
127 | PDPK1 | 0.40509861 |
128 | PRKCZ | 0.40082631 |
129 | TNK2 | 0.39649719 |
130 | PRKACA | 0.39384805 |
131 | ABL1 | 0.38971117 |
132 | PDK1 | 0.38883829 |
133 | ADRBK1 | 0.38867972 |
134 | PDGFRB | 0.37816257 |
135 | CDK9 | 0.37336890 |
136 | MAP3K5 | 0.37206735 |
137 | BLK | 0.36958366 |
138 | MAPK7 | 0.36255524 |
139 | IKBKB | 0.35408028 |
140 | EGFR | 0.34638681 |
141 | BMX | 0.34100490 |
142 | PRKCH | 0.32292069 |
143 | MAP3K1 | 0.31956965 |
144 | RET | 0.30551048 |
145 | AKT3 | 0.29246906 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 4.14694464 |
2 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.39635480 |
3 | Nitrogen metabolism_Homo sapiens_hsa00910 | 3.34781938 |
4 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.97312944 |
5 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.80544454 |
6 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.75648057 |
7 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.58161801 |
8 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.52158954 |
9 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 2.48917425 |
10 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.41750573 |
11 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.40909511 |
12 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.34408879 |
13 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.27057900 |
14 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.03849734 |
15 | Peroxisome_Homo sapiens_hsa04146 | 2.00566981 |
16 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.99996841 |
17 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.98587824 |
18 | Caffeine metabolism_Homo sapiens_hsa00232 | 1.96283254 |
19 | Histidine metabolism_Homo sapiens_hsa00340 | 1.88583980 |
20 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.85838522 |
21 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.81570289 |
22 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.81401904 |
23 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.77332784 |
24 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.76447738 |
25 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.75885110 |
26 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.75593624 |
27 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.75134347 |
28 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 1.74872055 |
29 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.64641861 |
30 | Retinol metabolism_Homo sapiens_hsa00830 | 1.61958111 |
31 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.61173410 |
32 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 1.59826365 |
33 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.52712203 |
34 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.51650440 |
35 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.51372073 |
36 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.50570702 |
37 | Bile secretion_Homo sapiens_hsa04976 | 1.45970362 |
38 | ABC transporters_Homo sapiens_hsa02010 | 1.39961978 |
39 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.39697257 |
40 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 1.37145203 |
41 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.28818953 |
42 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.27310573 |
43 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 1.21758259 |
44 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.20735692 |
45 | Lysine degradation_Homo sapiens_hsa00310 | 1.19842588 |
46 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.16577414 |
47 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.13451154 |
48 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.08713510 |
49 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.05347072 |
50 | Carbon metabolism_Homo sapiens_hsa01200 | 1.04427151 |
51 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.03359940 |
52 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.03132935 |
53 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.01845487 |
54 | Steroid biosynthesis_Homo sapiens_hsa00100 | 1.00596658 |
55 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.96439126 |
56 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.92007305 |
57 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.89828620 |
58 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.87635457 |
59 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 0.87106884 |
60 | Sulfur relay system_Homo sapiens_hsa04122 | 0.85835367 |
61 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 0.85270095 |
62 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.83562462 |
63 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.77690308 |
64 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.76056386 |
65 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 0.75854868 |
66 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.74434189 |
67 | Type I diabetes mellitus_Homo sapiens_hsa04940 | 0.66207412 |
68 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.65703576 |
69 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.64848162 |
70 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 0.63811704 |
71 | Circadian rhythm_Homo sapiens_hsa04710 | 0.62877736 |
72 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.61684551 |
73 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.56779549 |
74 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.54331645 |
75 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.52669186 |
76 | Protein export_Homo sapiens_hsa03060 | 0.48023529 |
77 | Insulin resistance_Homo sapiens_hsa04931 | 0.47998883 |
78 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 0.47908194 |
79 | Graft-versus-host disease_Homo sapiens_hsa05332 | 0.45686500 |
80 | Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.42815012 |
81 | Regulation of autophagy_Homo sapiens_hsa04140 | 0.38669897 |
82 | Allograft rejection_Homo sapiens_hsa05330 | 0.38473622 |
83 | Autoimmune thyroid disease_Homo sapiens_hsa05320 | 0.37280091 |
84 | Metabolic pathways_Homo sapiens_hsa01100 | 0.37087094 |
85 | Galactose metabolism_Homo sapiens_hsa00052 | 0.36621037 |
86 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.35072007 |
87 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.35028872 |
88 | Inflammatory bowel disease (IBD)_Homo sapiens_hsa05321 | 0.32999256 |
89 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.30691342 |
90 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 0.28705509 |
91 | Hematopoietic cell lineage_Homo sapiens_hsa04640 | 0.28181451 |
92 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.27597472 |
93 | Asthma_Homo sapiens_hsa05310 | 0.27036601 |
94 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.24916596 |
95 | Phototransduction_Homo sapiens_hsa04744 | 0.24912011 |
96 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 0.24453217 |
97 | Renin secretion_Homo sapiens_hsa04924 | 0.23943683 |
98 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 0.23195949 |
99 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.21438291 |
100 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.21047742 |
101 | Jak-STAT signaling pathway_Homo sapiens_hsa04630 | 0.19405718 |
102 | Pertussis_Homo sapiens_hsa05133 | 0.19097236 |
103 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.19013743 |
104 | Prion diseases_Homo sapiens_hsa05020 | 0.14985651 |
105 | Glycerophospholipid metabolism_Homo sapiens_hsa00564 | 0.14263096 |
106 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.14232171 |
107 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.14005320 |
108 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.13900261 |
109 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.11742576 |
110 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.11529950 |
111 | Other glycan degradation_Homo sapiens_hsa00511 | 0.11059381 |
112 | Hepatitis C_Homo sapiens_hsa05160 | 0.01386594 |
113 | Lysosome_Homo sapiens_hsa04142 | 0.00655934 |
114 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | -0.1123589 |
115 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | -0.1042908 |
116 | Type II diabetes mellitus_Homo sapiens_hsa04930 | -0.1033253 |
117 | Legionellosis_Homo sapiens_hsa05134 | -0.1012979 |
118 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | -0.0891934 |
119 | Pancreatic secretion_Homo sapiens_hsa04972 | -0.0880246 |
120 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | -0.0830775 |
121 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | -0.0777121 |
122 | Mineral absorption_Homo sapiens_hsa04978 | -0.0549722 |
123 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | -0.0439762 |
124 | Insulin signaling pathway_Homo sapiens_hsa04910 | -0.0395490 |
125 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | -0.0175953 |
126 | NF-kappa B signaling pathway_Homo sapiens_hsa04064 | -0.0112639 |