CTAGE5

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1L-phenylalanine catabolic process (GO:0006559)6.73219083
2erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222)6.73219083
3L-phenylalanine metabolic process (GO:0006558)6.45825212
4erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221)6.45825212
5aromatic amino acid family catabolic process (GO:0009074)6.15708784
6indole-containing compound catabolic process (GO:0042436)5.66423203
7indolalkylamine catabolic process (GO:0046218)5.66423203
8tryptophan catabolic process (GO:0006569)5.66423203
9triglyceride-rich lipoprotein particle remodeling (GO:0034370)5.55931581
10cysteine metabolic process (GO:0006534)5.50734727
11kynurenine metabolic process (GO:0070189)5.49105867
12tryptophan metabolic process (GO:0006568)5.39210841
13bile acid biosynthetic process (GO:0006699)5.28869709
14urea metabolic process (GO:0019627)5.21443972
15urea cycle (GO:0000050)5.21443972
16alpha-linolenic acid metabolic process (GO:0036109)5.18610613
17glyoxylate metabolic process (GO:0046487)5.17961216
18sulfur amino acid catabolic process (GO:0000098)5.08174860
19homocysteine metabolic process (GO:0050667)5.02970529
20fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540)4.98364076
21protein carboxylation (GO:0018214)4.87764116
22peptidyl-glutamic acid carboxylation (GO:0017187)4.87764116
23high-density lipoprotein particle remodeling (GO:0034375)4.85082685
24lysine catabolic process (GO:0006554)4.79271985
25lysine metabolic process (GO:0006553)4.79271985
26serine family amino acid catabolic process (GO:0009071)4.78682339
27nitrogen cycle metabolic process (GO:0071941)4.75994664
28complement activation, alternative pathway (GO:0006957)4.73547675
29negative regulation of fibrinolysis (GO:0051918)4.65074863
30bile acid metabolic process (GO:0008206)4.62882649
31regulation of protein activation cascade (GO:2000257)4.59227900
32regulation of fibrinolysis (GO:0051917)4.48275427
33regulation of triglyceride catabolic process (GO:0010896)4.47481496
34aromatic amino acid family metabolic process (GO:0009072)4.46667853
35amino-acid betaine metabolic process (GO:0006577)4.45410711
36epoxygenase P450 pathway (GO:0019373)4.40768754
37reverse cholesterol transport (GO:0043691)4.35560673
38regulation of complement activation (GO:0030449)4.30414796
39negative regulation of protein activation cascade (GO:2000258)4.28628286
40triglyceride homeostasis (GO:0070328)4.25748775
41acylglycerol homeostasis (GO:0055090)4.25748775
42intestinal cholesterol absorption (GO:0030299)4.25275965
43alpha-amino acid catabolic process (GO:1901606)4.24167824
44negative regulation of cholesterol transport (GO:0032375)4.23316273
45negative regulation of sterol transport (GO:0032372)4.23316273
46phospholipid efflux (GO:0033700)4.20326404
47tyrosine metabolic process (GO:0006570)4.17139503
48plasma lipoprotein particle remodeling (GO:0034369)4.15191575
49protein-lipid complex remodeling (GO:0034368)4.15191575
50macromolecular complex remodeling (GO:0034367)4.15191575
51intestinal absorption (GO:0050892)4.14308128
52cellular modified amino acid catabolic process (GO:0042219)4.11882618
53bile acid and bile salt transport (GO:0015721)4.11049952
54low-density lipoprotein particle remodeling (GO:0034374)4.10574135
55drug transmembrane transport (GO:0006855)4.09140138
56indolalkylamine metabolic process (GO:0006586)4.05571528
57valine metabolic process (GO:0006573)4.04227698
58regulation of cholesterol esterification (GO:0010872)4.03255610
59serine family amino acid metabolic process (GO:0009069)4.02435183
60glycine metabolic process (GO:0006544)4.01999543
61drug catabolic process (GO:0042737)3.99044386
62cellular amino acid catabolic process (GO:0009063)3.95832898
63plasma lipoprotein particle clearance (GO:0034381)3.94107975
64ethanol oxidation (GO:0006069)3.92498609
65cellular glucuronidation (GO:0052695)3.88943144
66negative regulation of complement activation (GO:0045916)3.87512843
67coenzyme catabolic process (GO:0009109)3.85364505
68regulation of cholesterol homeostasis (GO:2000188)3.82598143
69glutamate metabolic process (GO:0006536)3.82069358
70benzene-containing compound metabolic process (GO:0042537)3.81784173
71cholesterol efflux (GO:0033344)3.80664126
72cellular biogenic amine catabolic process (GO:0042402)3.79402342
73amine catabolic process (GO:0009310)3.79402342
74plasma lipoprotein particle assembly (GO:0034377)3.77927693
75cellular ketone body metabolic process (GO:0046950)3.77712930
76urate metabolic process (GO:0046415)3.73437739
77phospholipid homeostasis (GO:0055091)3.73367089
78serine family amino acid biosynthetic process (GO:0009070)3.70214118
79imidazole-containing compound metabolic process (GO:0052803)3.68931917
80plasma lipoprotein particle organization (GO:0071827)3.67912371
81dicarboxylic acid biosynthetic process (GO:0043650)3.66230946
82regulation of bile acid biosynthetic process (GO:0070857)3.63124831
83short-chain fatty acid metabolic process (GO:0046459)3.62100490
842-oxoglutarate metabolic process (GO:0006103)3.57303224
85cholesterol homeostasis (GO:0042632)3.56105136
86positive regulation of triglyceride lipase activity (GO:0061365)3.54857591
87positive regulation of lipoprotein lipase activity (GO:0051006)3.54857591
88sterol homeostasis (GO:0055092)3.53135533
89organic acid catabolic process (GO:0016054)3.51846248
90carboxylic acid catabolic process (GO:0046395)3.51846248
91very-low-density lipoprotein particle assembly (GO:0034379)3.48171796
92fatty acid oxidation (GO:0019395)3.48034454
93positive regulation of lipid catabolic process (GO:0050996)3.47629452
94fatty acid beta-oxidation (GO:0006635)3.46890561
95purine ribonucleoside bisphosphate metabolic process (GO:0034035)3.46839730
963-phosphoadenosine 5-phosphosulfate metabolic process (GO:0050427)3.46839730
97protein-lipid complex assembly (GO:0065005)3.46260565
98lipoprotein metabolic process (GO:0042157)3.45155049
99negative regulation of humoral immune response (GO:0002921)3.43777625
100sulfation (GO:0051923)3.43334433
101acetyl-CoA metabolic process (GO:0006084)3.42598399
102blood coagulation, intrinsic pathway (GO:0007597)3.41970026
103lipid oxidation (GO:0034440)3.40876267
104negative regulation of lipase activity (GO:0060192)3.40745263
105glucuronate metabolic process (GO:0019585)3.40447544
106uronic acid metabolic process (GO:0006063)3.40447544
107drug transport (GO:0015893)3.37914396
108fibrinolysis (GO:0042730)3.37321052
109protein-lipid complex subunit organization (GO:0071825)3.37233895
110exogenous drug catabolic process (GO:0042738)3.35540686
111flavonoid metabolic process (GO:0009812)3.35111833
112monocarboxylic acid catabolic process (GO:0072329)3.32389817
113ethanol metabolic process (GO:0006067)3.27196100
114drug metabolic process (GO:0017144)3.20629916
115regulation of systemic arterial blood pressure by renin-angiotensin (GO:0003081)3.13172529
116water-soluble vitamin biosynthetic process (GO:0042364)3.00994384
117regulation of humoral immune response (GO:0002920)2.98420272
118diacylglycerol metabolic process (GO:0046339)2.94163235
119lipoprotein transport (GO:0042953)2.92842462
120omega-hydroxylase P450 pathway (GO:0097267)2.90595376
121cholesterol transport (GO:0030301)2.90307601
122sterol transport (GO:0015918)2.90307601
123phenylpropanoid metabolic process (GO:0009698)2.87882856
124cellular anion homeostasis (GO:0030002)2.81817192
125negative regulation of hemostasis (GO:1900047)2.79291895
126negative regulation of blood coagulation (GO:0030195)2.79291895
127positive regulation of glycolytic process (GO:0045821)2.79066099
128protein activation cascade (GO:0072376)2.78905310
129vitamin transmembrane transport (GO:0035461)2.78666078
130L-ascorbic acid metabolic process (GO:0019852)2.78346485
131positive regulation of fatty acid oxidation (GO:0046321)2.76400728
132positive regulation of fatty acid beta-oxidation (GO:0032000)2.74689415
133vitamin biosynthetic process (GO:0009110)2.73320393
134acute-phase response (GO:0006953)2.67405894
135transepithelial transport (GO:0070633)2.65484815
136lipid homeostasis (GO:0055088)2.64487210
137negative regulation of coagulation (GO:0050819)2.64394876
138polyketide metabolic process (GO:0030638)2.63949732
139doxorubicin metabolic process (GO:0044598)2.63949732
140daunorubicin metabolic process (GO:0044597)2.63949732
141primary alcohol catabolic process (GO:0034310)2.62804477
142angiotensin maturation (GO:0002003)2.62006587
143primary alcohol metabolic process (GO:0034308)2.60501548
144oxidative demethylation (GO:0070989)2.59649961

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1RXR_22158963_ChIP-Seq_LIVER_Mouse7.55320501
2PPARA_22158963_ChIP-Seq_LIVER_Mouse6.64510551
3EGR1_23403033_ChIP-Seq_LIVER_Mouse6.02883649
4LXR_22158963_ChIP-Seq_LIVER_Mouse6.02110983
5FOXO1_23066095_ChIP-Seq_LIVER_Mouse4.56845389
6CEBPA_23403033_ChIP-Seq_LIVER_Mouse4.31463079
7PPARG_19300518_ChIP-PET_3T3-L1_Mouse4.18975563
8NR1I2_20693526_ChIP-Seq_LIVER_Mouse3.88599277
9CEBPB_23403033_ChIP-Seq_LIVER_Mouse3.43573292
10GATA1_22025678_ChIP-Seq_K562_Human2.36756463
11TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse2.14092716
12HNF4A_19761587_ChIP-ChIP_CACO-2_Human2.02338719
13IRF8_22096565_ChIP-ChIP_GC-B_Human2.01948345
14ESR1_17901129_ChIP-ChIP_LIVER_Mouse10.3234605
15POU3F2_20337985_ChIP-ChIP_501MEL_Human1.98087765
16* STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse1.92118654
17TCF7L2_21901280_ChIP-Seq_H4IIE_Rat1.90473375
18CDX2_19796622_ChIP-Seq_MESCs_Mouse1.88470305
19CLOCK_20551151_ChIP-Seq_293T_Human1.83286627
20FLI1_27457419_Chip-Seq_LIVER_Mouse1.77371335
21GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse1.76194345
22IRF1_21803131_ChIP-Seq_MONOCYTES_Human1.74176713
23* FOXA2_19822575_ChIP-Seq_HepG2_Human1.71487671
24VDR_22108803_ChIP-Seq_LS180_Human1.71435268
25AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human1.69855621
26GBX2_23144817_ChIP-Seq_PC3_Human1.66476408
27PCGF2_27294783_Chip-Seq_ESCs_Mouse1.65722834
28STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.62731391
29* ZNF274_21170338_ChIP-Seq_K562_Hela1.58284463
30ER_23166858_ChIP-Seq_MCF-7_Human1.56071557
31CEBPD_23245923_ChIP-Seq_MEFs_Mouse1.54350969
32SOX2_27498859_Chip-Seq_STOMACH_Mouse1.53076537
33ZFP57_27257070_Chip-Seq_ESCs_Mouse1.52826197
34BCAT_22108803_ChIP-Seq_LS180_Human1.52636066
35IGF1R_20145208_ChIP-Seq_DFB_Human1.51861126
36GLI1_17442700_ChIP-ChIP_MESCs_Mouse1.49649785
37EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human1.49577097
38FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse1.48980206
39BCL11B_21912641_ChIP-Seq_STHDH_STRIUM_Mouse1.47220027
40* HNF4A_19822575_ChIP-Seq_HepG2_Human1.45914366
41SUZ12_27294783_Chip-Seq_NPCs_Mouse1.43632494
42PIAS1_25552417_ChIP-Seq_VCAP_Human1.36950118
43NFE2_27457419_Chip-Seq_LIVER_Mouse1.36643943
44TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.36094475
45EZH2_27294783_Chip-Seq_NPCs_Mouse1.35133009
46* STAT3_23295773_ChIP-Seq_U87_Human1.34806436
47PCGF2_27294783_Chip-Seq_NPCs_Mouse1.34355582
48GATA4_25053715_ChIP-Seq_YYC3_Human1.33105395
49FOXM1_26456572_ChIP-Seq_MCF-7_Human1.30995288
50IRF4_20064451_ChIP-Seq_CD4+T_Mouse1.30743625
51CBP_20019798_ChIP-Seq_JUKART_Human1.30743625
52ZNF217_24962896_ChIP-Seq_MCF-7_Human1.29629045
53* CDX2_21402776_ChIP-Seq_INTESTINAL-VILLUS_Mouse1.29137456
54* SMARCD1_25818293_ChIP-Seq_ESCs_Mouse1.29003414
55CTNNB1_24651522_ChIP-Seq_LGR5+_INTESTINAL_STEM_Human1.27957440
56* Nerf2_26677805_Chip-Seq_MACROPHAGESS_Mouse1.24665487
57AHR_22903824_ChIP-Seq_MCF-7_Human1.24049152
58TCF4_23295773_ChIP-Seq_U87_Human1.23376329
59TP53_16413492_ChIP-PET_HCT116_Human1.23284760
60TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.20892973
61NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.17806603
62UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human1.17697675
63SMAD4_21799915_ChIP-Seq_A2780_Human1.17247632
64CRX_20693478_ChIP-Seq_RETINA_Mouse1.16473250
65MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse1.15573790
66FOXA1_21572438_ChIP-Seq_LNCaP_Human1.15326980
67IRF8_21731497_ChIP-ChIP_J774_Mouse1.15111608
68NR3C1_21868756_ChIP-Seq_MCF10A_Human1.13991561
69TCF4_22108803_ChIP-Seq_LS180_Human1.13761508
70P300_19829295_ChIP-Seq_ESCs_Human1.13489164
71EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human1.12980208
72TAF15_26573619_Chip-Seq_HEK293_Human1.12813760
73EBF1_22473956_ChIP-Seq_BONE_MARROW_Mouse1.12710683
74ARNT_22903824_ChIP-Seq_MCF-7_Human1.11277509
75CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse1.10781998
76GATA6_25053715_ChIP-Seq_YYC3_Human1.10646429
77STAT3_18555785_Chip-Seq_ESCs_Mouse1.10455666
78FOXA1_25329375_ChIP-Seq_VCAP_Human1.10240074
79FOXA1_27270436_Chip-Seq_PROSTATE_Human1.10240074
80SOX6_21985497_ChIP-Seq_MYOTUBES_Mouse1.10182624
81TCF4_18268006_ChIP-ChIP_LS174T_Human1.09973959
82SOX2_19829295_ChIP-Seq_ESCs_Human1.09727310
83NANOG_19829295_ChIP-Seq_ESCs_Human1.09727310
84SMAD4_21741376_ChIP-Seq_EPCs_Human1.09719041
85TP63_23658742_ChIP-Seq_EP156T_Human1.09614268
86NCOR_22465074_ChIP-Seq_MACROPHAGES_Mouse1.08297158
87RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human1.08257336
88* SMRT_22465074_ChIP-Seq_MACROPHAGES_Mouse1.07772644
89ESR1_21235772_ChIP-Seq_MCF-7_Human1.07743755
90P53_22387025_ChIP-Seq_ESCs_Mouse1.07116963
91TCFCP2L1_18555785_Chip-Seq_ESCs_Mouse1.05414142
92OCT4_21477851_ChIP-Seq_ESCs_Mouse1.04976208
93NANOG_18555785_Chip-Seq_ESCs_Mouse1.04846409
94KLF5_20875108_ChIP-Seq_MESCs_Mouse1.04830393
95AR_25329375_ChIP-Seq_VCAP_Human1.04476664
96FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human1.03660254
97RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse1.02437649
98FOXO3_23340844_ChIP-Seq_DLD1_Human1.02378534
99OCT4_18555785_Chip-Seq_ESCs_Mouse1.02155180
100AR_21915096_ChIP-Seq_LNCaP-1F5_Human0.99356198
101RXRA_24833708_ChIP-Seq_LIVER_Mouse0.98917812
102HTT_18923047_ChIP-ChIP_STHdh_Human0.98628974
103* BRD4_27068464_Chip-Seq_AML-cells_Mouse0.94149129
104* IRF8_27001747_Chip-Seq_BMDM_Mouse0.92821054
105ESR2_21235772_ChIP-Seq_MCF-7_Human0.92682453
106CDX2_20551321_ChIP-Seq_CACO-2_Human0.91532964
107FOXA1_26743006_Chip-Seq_LNCaP-abl_Human0.89894366
108NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human0.89856628
109ZNF652_21678463_ChIP-ChIP_ZR75-1_Human0.88732702
110FOXA1_21915096_ChIP-Seq_LNCaP-1F5_Human0.85259020
111PPAR_26484153_Chip-Seq_NCI-H1993_Human0.84387390
112SALL4_18804426_ChIP-ChIP_XEN_Mouse0.84256574
113PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse0.82177658
114ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.82138127
115FOXA1_25552417_ChIP-Seq_VCAP_Human0.79179867
116FOXA1_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.76378144
117BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human0.76167781
118STAT6_20620947_ChIP-Seq_CD4_POS_T_Human0.75277783
119THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse0.74687626
120ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human0.74406234
121RARG_19884340_ChIP-ChIP_MEFs_Mouse0.72610255
122KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human0.71395720
123SREBP2_21459322_ChIP-Seq_LIVER_Mouse0.71249962
124GATA2_19941826_ChIP-Seq_K562_Human0.70389734
125MYB_21317192_ChIP-Seq_ERMYB_Mouse0.68876092
126ESR1_20079471_ChIP-ChIP_T-47D_Human0.66127408
127GATA1_19941827_ChIP-Seq_MEL_Mouse0.65949984
128TP63_17297297_ChIP-ChIP_HaCaT_Human0.65248608
129GATA3_24758297_ChIP-Seq_MCF-7_Human0.64183710
130RARA_24833708_ChIP-Seq_LIVER_Mouse0.63835462
131FOXP3_17237761_ChIP-ChIP_TREG_Mouse0.63730222
132GATA1_19941826_ChIP-Seq_K562_Human0.63263472
133CEBPB_22108803_ChIP-Seq_LS180_Human0.62719971
134SOX2_20726797_ChIP-Seq_SW620_Human0.61676263
135RUNX_20019798_ChIP-Seq_JUKART_Human0.61641083
136* MYB_26560356_Chip-Seq_TH1_Human0.60813136
137STAT3_1855785_ChIP-Seq_MESCs_Mouse0.60630030
138GATA2_22383799_ChIP-Seq_G1ME_Mouse0.60533665
139KAP1_22055183_ChIP-Seq_ESCs_Mouse0.60097148
140KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human0.59945404
141PPARG_20887899_ChIP-Seq_3T3-L1_Mouse0.59943242
142AUTS2_25519132_ChIP-Seq_293T-REX_Human0.59814368
143IRF8_22096565_ChIP-ChIP_GC-B_Mouse0.59002693
144GATA2_20887958_ChIP-Seq_HPC-7_Mouse0.58921940
145GATA2_21666600_ChIP-Seq_HMVEC_Human0.58745043
146BMI1_19503595_ChIP-Seq_MEFsC_Mouse0.58374020
147ERA_27197147_Chip-Seq_ENDOMETRIOID-ADENOCARCINOMA_Human0.57629175
148EGR1_19032775_ChIP-ChIP_M12_Human0.56733300
149SCL_19346495_ChIP-Seq_HPC-7_Human0.56674387
150TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human0.56376038
151RACK7_27058665_Chip-Seq_MCF-7_Human0.56217424
152STAT3_20064451_ChIP-Seq_CD4+T_Mouse0.55463733
153CDX2_22108803_ChIP-Seq_LS180_Human0.55131640
154E2A_27217539_Chip-Seq_RAMOS-Cell_line_Human0.54768019
155* PU_27001747_Chip-Seq_BMDM_Mouse0.54151947
156AR_20517297_ChIP-Seq_VCAP_Human0.54145421
157FOXO1_25302145_ChIP-Seq_T-LYMPHOCYTE_Mouse0.54079167
158* TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse0.53515114
159KDM2B_26808549_Chip-Seq_HPB-ALL_Human0.52969001
160SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.52816310
161* TBX20_22328084_ChIP-Seq_HEART_Mouse0.52134519
162* TBX20_22080862_ChIP-Seq_HEART_Mouse0.52134519
163RUNX1_20887958_ChIP-Seq_HPC-7_Mouse0.52031954
164PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse0.50957052

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0002139_abnormal_hepatobiliary_system7.38527390
2MP0005360_urolithiasis6.95091478
3MP0005365_abnormal_bile_salt5.78053667
4MP0005085_abnormal_gallbladder_physiolo5.77328429
5MP0008875_abnormal_xenobiotic_pharmacok4.47541778
6MP0003252_abnormal_bile_duct3.96733360
7MP0003806_abnormal_nucleotide_metabolis3.16077660
8MP0010329_abnormal_lipoprotein_level3.11540328
9MP0001666_abnormal_nutrient_absorption3.02028864
10MP0005083_abnormal_biliary_tract2.95318001
11MP0009840_abnormal_foam_cell2.81162442
12MP0003183_abnormal_peptide_metabolism2.60098001
13MP0003195_calcinosis2.57425908
14MP0005332_abnormal_amino_acid2.57323950
15MP0002138_abnormal_hepatobiliary_system2.40022569
16MP0004019_abnormal_vitamin_homeostasis2.25654570
17MP0003191_abnormal_cellular_cholesterol2.17152628
18MP0000609_abnormal_liver_physiology2.13425626
19MP0003868_abnormal_feces_composition1.99923185
20MP0002118_abnormal_lipid_homeostasis1.93609960
21MP0009780_abnormal_chondrocyte_physiolo1.88218918
22MP0005319_abnormal_enzyme/_coenzyme1.72888554
23MP0005379_endocrine/exocrine_gland_phen1.59970571
24MP0009643_abnormal_urine_homeostasis1.59251614
25MP0002132_abnormal_respiratory_system1.55170732
26MP0001764_abnormal_homeostasis1.42780130
27MP0003300_gastrointestinal_ulcer1.38067614
28MP0003646_muscle_fatigue1.34916440
29MP0005451_abnormal_body_composition1.34135651
30MP0003705_abnormal_hypodermis_morpholog1.32126146
31MP0005584_abnormal_enzyme/coenzyme_acti1.31171617
32MP0005220_abnormal_exocrine_pancreas1.30330677
33MP0002160_abnormal_reproductive_system1.26906787
34MP0003122_maternal_imprinting1.24611553
35MP0008872_abnormal_physiological_respon1.22273135
36MP0000598_abnormal_liver_morphology1.18729425
37MP0002837_dystrophic_cardiac_calcinosis1.16414816
38MP0009764_decreased_sensitivity_to1.13111380
39MP0002254_reproductive_system_inflammat1.12746217
40MP0005670_abnormal_white_adipose1.12668184
41MP0003186_abnormal_redox_activity1.11568645
42MP0005636_abnormal_mineral_homeostasis1.08744282
43MP0004264_abnormal_extraembryonic_tissu1.07183036
44MP0002163_abnormal_gland_morphology1.06199344
45MP0003656_abnormal_erythrocyte_physiolo1.03450435
46MP0009785_altered_susceptibility_to1.02789714
47MP0005647_abnormal_sex_gland1.02576804
48MP0005389_reproductive_system_phenotype1.01420489
49MP0003011_delayed_dark_adaptation1.00895458
50MP0008469_abnormal_protein_level1.00621848
51MP0001986_abnormal_taste_sensitivity0.99288851
52MP0003879_abnormal_hair_cell0.98565759
53MP0009763_increased_sensitivity_to0.97121288
54MP0004145_abnormal_muscle_electrophysio0.96418242
55MP0009697_abnormal_copulation0.95702448
56MP0005646_abnormal_pituitary_gland0.95087002
57MP0004134_abnormal_chest_morphology0.95014673
58MP0003866_abnormal_defecation0.92935374
59MP0005551_abnormal_eye_electrophysiolog0.92723333
60MP0003172_abnormal_lysosome_physiology0.90970074
61MP0005410_abnormal_fertilization0.90875796
62MP0003718_maternal_effect0.90486310
63MP0002078_abnormal_glucose_homeostasis0.90440075
64MP0000685_abnormal_immune_system0.87359162
65MP0009642_abnormal_blood_homeostasis0.87224392
66MP0002928_abnormal_bile_duct0.85376789
67MP0002277_abnormal_respiratory_mucosa0.84964590
68MP0005408_hypopigmentation0.84935391
69MP0001756_abnormal_urination0.84582920
70MP0000013_abnormal_adipose_tissue0.84236725
71MP0003950_abnormal_plasma_membrane0.84202148
72MP0005084_abnormal_gallbladder_morpholo0.83928156
73MP0003436_decreased_susceptibility_to0.83297042
74MP0002909_abnormal_adrenal_gland0.83170889
75MP0005334_abnormal_fat_pad0.82576072
76MP0004043_abnormal_pH_regulation0.82144002
77MP0002136_abnormal_kidney_physiology0.80896945
78MP0002971_abnormal_brown_adipose0.80362990
79MP0010234_abnormal_vibrissa_follicle0.77788841
80MP0009765_abnormal_xenobiotic_induced0.77421697
81MP0005058_abnormal_lysosome_morphology0.77396898
82MP0005666_abnormal_adipose_tissue0.76914466
83MP0001790_abnormal_immune_system0.76094833
84MP0005387_immune_system_phenotype0.76094833
85MP0010678_abnormal_skin_adnexa0.75271896
86MP0000427_abnormal_hair_cycle0.73952193
87MP0004484_altered_response_of0.73794637
88MP0004130_abnormal_muscle_cell0.73769724
89MP0008877_abnormal_DNA_methylation0.73347854
90MP0005464_abnormal_platelet_physiology0.72277567
91MP0005310_abnormal_salivary_gland0.70953676
92MP0001661_extended_life_span0.70477238
93MP0004142_abnormal_muscle_tone0.68640093
94MP0000604_amyloidosis0.67784258
95MP0000383_abnormal_hair_follicle0.67574423
96MP0001800_abnormal_humoral_immune0.65501672
97MP0001485_abnormal_pinna_reflex0.64980736
98MP0002876_abnormal_thyroid_physiology0.63640886
99MP0001845_abnormal_inflammatory_respons0.63534518
100MP0001765_abnormal_ion_homeostasis0.63345738
101MP0005164_abnormal_response_to0.62868105
102MP0003724_increased_susceptibility_to0.62609083
103MP0006036_abnormal_mitochondrial_physio0.62332865
104MP0001664_abnormal_digestion0.61819914
105MP0000569_abnormal_digit_pigmentation0.61223292
106MP0005025_abnormal_response_to0.61185738
107MP0004185_abnormal_adipocyte_glucose0.61177639
108MP0001944_abnormal_pancreas_morphology0.60463991
109MP0004947_skin_inflammation0.59023513
110MP0009053_abnormal_anal_canal0.58741557
111MP0005535_abnormal_body_temperature0.58626216
112MP0010368_abnormal_lymphatic_system0.58182994
113MP0002166_altered_tumor_susceptibility0.57811307
114MP0005376_homeostasis/metabolism_phenot0.56729083
115MP0001881_abnormal_mammary_gland0.56672853
116MP0004782_abnormal_surfactant_physiolog0.56082612
117MP0006082_CNS_inflammation0.55679421
118MP0005448_abnormal_energy_balance0.55557356
119MP0001853_heart_inflammation0.55516177
120MP0009384_cardiac_valve_regurgitation0.53490523
121MP0002693_abnormal_pancreas_physiology0.52943089
122MP0010155_abnormal_intestine_physiology0.51652477
123MP0001873_stomach_inflammation0.49263716
124MP0009115_abnormal_fat_cell0.49109568
125MP0002796_impaired_skin_barrier0.48906482
126MP0002168_other_aberrant_phenotype0.47974366
127MP0003453_abnormal_keratinocyte_physiol0.47373104
128MP0005248_abnormal_Harderian_gland0.47339837
129MP0003953_abnormal_hormone_level0.47213051
130MP0000639_abnormal_adrenal_gland0.46361325
131MP0005395_other_phenotype0.45726880
132MP0003638_abnormal_response/metabolism_0.44833481
133MP0002060_abnormal_skin_morphology0.44072962
134MP0009672_abnormal_birth_weight0.43141586
135MP0000579_abnormal_nail_morphology0.42803765
136MP0003959_abnormal_lean_body0.40865029
137MP0008961_abnormal_basal_metabolism0.40809821
138MP0002970_abnormal_white_adipose0.40781252
139MP0004381_abnormal_hair_follicle0.40768100
140MP0001835_abnormal_antigen_presentation0.40373090
141MP0005266_abnormal_metabolism0.39260424
142MP0003303_peritoneal_inflammation0.39150960

Predicted human phenotypes

RankGene SetZ-score
1Intrahepatic cholestasis (HP:0001406)6.82011337
2Abnormality of aromatic amino acid family metabolism (HP:0004338)6.34602019
3Deep venous thrombosis (HP:0002625)6.23579007
4Abnormality of monocarboxylic acid metabolism (HP:0010996)5.95491987
5Xanthomatosis (HP:0000991)5.60576682
6Hypobetalipoproteinemia (HP:0003563)5.38955526
7Prolonged partial thromboplastin time (HP:0003645)5.37429126
8Complement deficiency (HP:0004431)4.71436152
9Hyperlipoproteinemia (HP:0010980)4.49751841
10Abnormality of glutamine family amino acid metabolism (HP:0010902)4.36158458
11Hypoglycemic coma (HP:0001325)4.31886285
12Joint hemorrhage (HP:0005261)4.30534371
13Abnormality of the common coagulation pathway (HP:0010990)4.25651293
14Ketosis (HP:0001946)4.23890999
15Fat malabsorption (HP:0002630)4.21642883
16Hypolipoproteinemia (HP:0010981)4.18312536
17Hyperammonemia (HP:0001987)4.18122361
18Epidermoid cyst (HP:0200040)4.14780938
19Hyperglycinuria (HP:0003108)4.14719193
20Hyperglycinemia (HP:0002154)4.09891781
21Abnormality of sulfur amino acid metabolism (HP:0004339)4.09856829
22Abnormality of glycine metabolism (HP:0010895)3.88228528
23Abnormality of serine family amino acid metabolism (HP:0010894)3.88228528
24Abnormality of aspartate family amino acid metabolism (HP:0010899)3.86857547
25Abnormality of the level of lipoprotein cholesterol (HP:0010979)3.83154708
26Conjugated hyperbilirubinemia (HP:0002908)3.81093557
27Abnormality of the intrinsic pathway (HP:0010989)3.75484629
28Hypoalphalipoproteinemia (HP:0003233)3.75219354
29Abnormality of methionine metabolism (HP:0010901)3.65393778
30Abnormality of complement system (HP:0005339)3.47267554
31Ketoacidosis (HP:0001993)3.47100421
32Abnormality of purine metabolism (HP:0004352)3.31282004
33Abnormality of nucleobase metabolism (HP:0010932)3.31190985
34Abnormality of pyrimidine metabolism (HP:0004353)3.31008947
35Myocardial infarction (HP:0001658)3.22172876
36Abnormality of fatty-acid metabolism (HP:0004359)3.21365112
37Hypercholesterolemia (HP:0003124)3.19959199
38Hypoglycemic seizures (HP:0002173)3.07615554
39Steatorrhea (HP:0002570)3.06847949
40Gout (HP:0001997)3.05798665
41Abnormality of long-chain fatty-acid metabolism (HP:0010964)3.04161036
42Hyperbilirubinemia (HP:0002904)3.02985325
43Hepatocellular carcinoma (HP:0001402)2.85304053
44Abnormality of serum amino acid levels (HP:0003112)2.76137465
45Abnormality of the nasal septum (HP:0000419)2.75434945
46Abnormality of vitamin metabolism (HP:0100508)2.74865878
47Vascular calcification (HP:0004934)2.74009697
48Abnormality of vitamin B metabolism (HP:0004340)2.73026755
49Abnormality of the renal cortex (HP:0011035)2.70303249
50Skin nodule (HP:0200036)2.68503531
51Dynein arm defect of respiratory motile cilia (HP:0012255)2.68422043
52Absent/shortened dynein arms (HP:0200106)2.68422043
53Metabolic acidosis (HP:0001942)2.67979181
54Hyperinsulinemic hypoglycemia (HP:0000825)2.66686246
55Systemic lupus erythematosus (HP:0002725)2.65713820
56Hypochromic microcytic anemia (HP:0004840)2.62384208
57Acanthocytosis (HP:0001927)2.57939835
58Esophageal varix (HP:0002040)2.52537395
59Pigmentary retinal degeneration (HP:0001146)2.52502726
60Generalized aminoaciduria (HP:0002909)2.52069958
61Hypothermia (HP:0002045)2.47771754
62Delayed CNS myelination (HP:0002188)2.46056862
63Abnormality of dicarboxylic acid metabolism (HP:0010995)2.43866977
64Dicarboxylic aciduria (HP:0003215)2.43866977
65Cardiovascular calcification (HP:0011915)2.42910768
66Decreased circulating renin level (HP:0003351)2.41252536
67Late onset (HP:0003584)2.40363261
68Pancreatitis (HP:0001733)2.40200053
69Malnutrition (HP:0004395)2.38940912
70Abnormality of the vitamin B12 metabolism (HP:0004341)2.37994706
71Recurrent gram-negative bacterial infections (HP:0005420)2.37624696
72Pancreatic cysts (HP:0001737)2.37469894
73Hydroxyprolinuria (HP:0003080)2.37421396
74Abnormality of proline metabolism (HP:0010907)2.37421396
75Hyperglycemia (HP:0003074)2.34636143
76Gingival bleeding (HP:0000225)2.34513705
77Symptomatic seizures (HP:0011145)2.33768995
78Confusion (HP:0001289)2.31683831
79Decreased central vision (HP:0007663)2.31147101
80Fair hair (HP:0002286)2.30630639
81Hypophosphatemic rickets (HP:0004912)2.30543650
82Glomerulonephritis (HP:0000099)2.30371702
83Menorrhagia (HP:0000132)2.25373432
84Abnormal respiratory epithelium morphology (HP:0012253)2.24988759
85Abnormal respiratory motile cilium morphology (HP:0005938)2.24988759
86Sensorimotor neuropathy (HP:0007141)2.23493627
87Abnormal ciliary motility (HP:0012262)2.22419765
88Hyperuricemia (HP:0002149)2.21620728
89Increased purine levels (HP:0004368)2.21620728
90Proximal tubulopathy (HP:0000114)2.21286391
91Chronic diarrhea (HP:0002028)2.20698534
92Congenital sensorineural hearing impairment (HP:0008527)2.20641884
93Mitral stenosis (HP:0001718)2.20599334
94Spontaneous abortion (HP:0005268)2.20263044
95Pancreatic fibrosis (HP:0100732)2.19543992
96Lethargy (HP:0001254)2.16848991
97Osteomalacia (HP:0002749)2.16564429
98Spastic diplegia (HP:0001264)2.15050628
99Pancreatic islet-cell hyperplasia (HP:0004510)2.13969152
100True hermaphroditism (HP:0010459)2.12625653
101Respiratory insufficiency due to defective ciliary clearance (HP:0200073)2.12165627
102Abnormal enzyme/coenzyme activity (HP:0012379)2.11673996
103Irritability (HP:0000737)2.09606476
104Renal cortical cysts (HP:0000803)2.07436797
105Alkalosis (HP:0001948)2.07207432
106Potter facies (HP:0002009)2.03951127
107Facial shape deformation (HP:0011334)2.03951127
108Abolished electroretinogram (ERG) (HP:0000550)2.02967640
109Abnormal gallbladder morphology (HP:0012437)2.01642232
110Abnormal respiratory motile cilium physiology (HP:0012261)2.01604988
111Thrombophlebitis (HP:0004418)1.98657030
112Genetic anticipation (HP:0003743)1.98030170
113Abnormality of transition element cation homeostasis (HP:0011030)1.95130454
114Neonatal onset (HP:0003623)1.94866124
115Methylmalonic acidemia (HP:0002912)1.94787844
116Rhinitis (HP:0012384)1.94456314
117Enlarged kidneys (HP:0000105)1.93897637
118Cholelithiasis (HP:0001081)1.91834275
119Furrowed tongue (HP:0000221)1.90802279
120Poikilocytosis (HP:0004447)1.90115854
121Hemorrhage of the eye (HP:0011885)1.89971946
122Abnormality of alkaline phosphatase activity (HP:0004379)1.89877244
123Elevated alkaline phosphatase (HP:0003155)1.89770759
124Hyperkalemia (HP:0002153)1.89134533
125Rickets (HP:0002748)1.88985235
126Azoospermia (HP:0000027)1.87966278
127Abnormal cartilage morphology (HP:0002763)1.86214805
128Amyloidosis (HP:0011034)1.84096740
129Nephritis (HP:0000123)1.83219491
130Elevated hepatic transaminases (HP:0002910)1.82398246
131Cystic liver disease (HP:0006706)1.82387816
132Arthropathy (HP:0003040)1.81788290
133Acute hepatic failure (HP:0006554)1.80578893
134Vomiting (HP:0002013)1.80351265
135Glycosuria (HP:0003076)1.80245416
136Abnormality of urine glucose concentration (HP:0011016)1.80245416
137Abnormality of iron homeostasis (HP:0011031)1.79450190
138Chronic hepatic failure (HP:0100626)1.77889148
139Progressive cerebellar ataxia (HP:0002073)1.74278912
140Methylmalonic aciduria (HP:0012120)1.74019908
141Generalized hypopigmentation of hair (HP:0011358)1.73953080
142Recurrent sinusitis (HP:0011108)1.72190177
143Joint swelling (HP:0001386)1.71279430
144Bronchiectasis (HP:0002110)1.69882274
145Hyperactive renin-angiotensin system (HP:0000841)1.68042987

Predicted kinase interactions (KEA)

RankGene SetZ-score
1BCKDK4.39486617
2ERN14.06593493
3TAOK33.98226007
4ACVR1B3.90529530
5INSRR3.45281889
6SIK13.29987946
7FGFR43.22497642
8MST42.58057246
9FRK2.49445494
10LATS12.40493143
11PKN22.36263455
12TRIB32.23539420
13OBSCN2.11396959
14MAP4K22.04547442
15PIK3CA2.04510998
16STK392.02470630
17MAP3K121.98881934
18IRAK31.96032472
19FLT31.91549744
20ADRBK21.90646983
21BMPR1B1.89016208
22MST1R1.87293360
23PTK61.82230779
24TYK21.70567417
25PIK3CG1.57685919
26ERBB41.56070569
27NEK91.51148566
28OXSR11.46750415
29MAPK111.45188176
30JAK11.41496907
31TGFBR21.39227525
32MAP2K61.38031675
33CDK121.36466885
34PINK11.36043961
35MAPKAPK31.35579715
36MAP3K141.34336171
37CAMK1D1.33465348
38MAP4K11.32526227
39STK38L1.30571190
40JAK21.29551489
41MAP3K101.27280671
42PHKG21.25261539
43PHKG11.25261539
44MAP3K71.22402710
45PRKAA21.19286222
46FER1.19078093
47WNK31.17868330
48STK101.16593549
49FGFR31.15985094
50GRK61.14995935
51MAP2K31.14837624
52CSK1.12552949
53EIF2AK31.11241807
54STK241.11188616
55TRPM71.11018793
56MAP3K31.09872556
57EPHB11.08124952
58NUAK11.06178591
59CDK61.04508671
60STK31.03228762
61JAK31.02860984
62TBK11.00794965
63ZAP700.99778803
64RIPK10.91016874
65EPHA30.86508674
66ITK0.86367616
67MAPK150.86141475
68PAK30.85003831
69CAMKK20.84978353
70BRSK20.84551797
71BMPR20.80450292
72SGK30.79945353
73WNK10.76189431
74PDK20.75983616
75CAMK1G0.75660779
76TXK0.75435016
77GSK3A0.74164989
78PRKAA10.70566635
79CSF1R0.68832235
80ERBB30.68760244
81NLK0.68242582
82IKBKE0.68182055
83DYRK1B0.67793908
84CDK40.67671242
85EPHA20.67101467
86FGFR20.66713710
87MAP2K40.65672588
88TLK10.64543356
89WNK40.64193810
90PTK20.63914168
91SGK10.62197176
92MTOR0.61662814
93MATK0.59458232
94MUSK0.59374138
95MET0.59148431
96LRRK20.59007886
97SYK0.57918538
98ERBB20.57537242
99PTK2B0.57064130
100IRAK10.55843204
101MAP2K20.55718373
102EEF2K0.55497244
103PRKCE0.54968279
104BTK0.54966808
105PDGFRA0.54681291
106CHUK0.54409952
107IRAK40.53676671
108TEC0.52659587
109LCK0.52051096
110LYN0.51487422
111KDR0.49374268
112PRKCQ0.48061797
113RPS6KB10.47185002
114IGF1R0.45130522
115MAPK40.44590489
116PRKACG0.44130968
117PIM10.43151297
118HIPK20.42872382
119GRK10.41577931
120MAP3K40.41182607
121SGK20.41146578
122PRKG20.41052014
123ZAK0.40996362
124KIT0.40908041
125MAP3K20.40869544
126ABL20.40867679
127PDPK10.40509861
128PRKCZ0.40082631
129TNK20.39649719
130PRKACA0.39384805
131ABL10.38971117
132PDK10.38883829
133ADRBK10.38867972
134PDGFRB0.37816257
135CDK90.37336890
136MAP3K50.37206735
137BLK0.36958366
138MAPK70.36255524
139IKBKB0.35408028
140EGFR0.34638681
141BMX0.34100490
142PRKCH0.32292069
143MAP3K10.31956965
144RET0.30551048
145AKT30.29246906

Predicted pathways (KEGG)

RankGene SetZ-score
1Primary bile acid biosynthesis_Homo sapiens_hsa001204.14694464
2Ascorbate and aldarate metabolism_Homo sapiens_hsa000533.39635480
3Nitrogen metabolism_Homo sapiens_hsa009103.34781938
4Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004002.97312944
5Arginine biosynthesis_Homo sapiens_hsa002202.80544454
6Tryptophan metabolism_Homo sapiens_hsa003802.75648057
7Fatty acid degradation_Homo sapiens_hsa000712.58161801
8Valine, leucine and isoleucine degradation_Homo sapiens_hsa002802.52158954
9Complement and coagulation cascades_Homo sapiens_hsa046102.48917425
10Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006302.41750573
11Pentose and glucuronate interconversions_Homo sapiens_hsa000402.40909511
12Glycine, serine and threonine metabolism_Homo sapiens_hsa002602.34408879
13Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010402.27057900
14Propanoate metabolism_Homo sapiens_hsa006402.03849734
15Peroxisome_Homo sapiens_hsa041462.00566981
16Drug metabolism - cytochrome P450_Homo sapiens_hsa009821.99996841
17Butanoate metabolism_Homo sapiens_hsa006501.98587824
18Caffeine metabolism_Homo sapiens_hsa002321.96283254
19Histidine metabolism_Homo sapiens_hsa003401.88583980
20PPAR signaling pathway_Homo sapiens_hsa033201.85838522
21Maturity onset diabetes of the young_Homo sapiens_hsa049501.81570289
22Fatty acid metabolism_Homo sapiens_hsa012121.81401904
23beta-Alanine metabolism_Homo sapiens_hsa004101.77332784
24Chemical carcinogenesis_Homo sapiens_hsa052041.76447738
25Selenocompound metabolism_Homo sapiens_hsa004501.75885110
26Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa009801.75593624
27Steroid hormone biosynthesis_Homo sapiens_hsa001401.75134347
28Staphylococcus aureus infection_Homo sapiens_hsa051501.74872055
29Drug metabolism - other enzymes_Homo sapiens_hsa009831.64641861
30Retinol metabolism_Homo sapiens_hsa008301.61958111
31Pantothenate and CoA biosynthesis_Homo sapiens_hsa007701.61173410
32Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa006011.59826365
33Fat digestion and absorption_Homo sapiens_hsa049751.52712203
34Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002501.51650440
35Sulfur metabolism_Homo sapiens_hsa009201.51372073
36Starch and sucrose metabolism_Homo sapiens_hsa005001.50570702
37Bile secretion_Homo sapiens_hsa049761.45970362
38ABC transporters_Homo sapiens_hsa020101.39961978
39Phenylalanine metabolism_Homo sapiens_hsa003601.39697257
402-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.37145203
41Folate biosynthesis_Homo sapiens_hsa007901.28818953
42Pyruvate metabolism_Homo sapiens_hsa006201.27310573
43Vitamin digestion and absorption_Homo sapiens_hsa049771.21758259
44Tyrosine metabolism_Homo sapiens_hsa003501.20735692
45Lysine degradation_Homo sapiens_hsa003101.19842588
46Synthesis and degradation of ketone bodies_Homo sapiens_hsa000721.16577414
47Cyanoamino acid metabolism_Homo sapiens_hsa004601.13451154
48Cysteine and methionine metabolism_Homo sapiens_hsa002701.08713510
49Fatty acid elongation_Homo sapiens_hsa000621.05347072
50Carbon metabolism_Homo sapiens_hsa012001.04427151
51Biosynthesis of amino acids_Homo sapiens_hsa012301.03359940
52Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001301.03132935
53Ether lipid metabolism_Homo sapiens_hsa005651.01845487
54Steroid biosynthesis_Homo sapiens_hsa001001.00596658
55Arginine and proline metabolism_Homo sapiens_hsa003300.96439126
56Proximal tubule bicarbonate reclamation_Homo sapiens_hsa049640.92007305
57One carbon pool by folate_Homo sapiens_hsa006700.89828620
58Glycerolipid metabolism_Homo sapiens_hsa005610.87635457
59Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.87106884
60Sulfur relay system_Homo sapiens_hsa041220.85835367
61Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.85270095
62Nicotinate and nicotinamide metabolism_Homo sapiens_hsa007600.83562462
63Vitamin B6 metabolism_Homo sapiens_hsa007500.77690308
64Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa005330.76056386
65Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.75854868
66Taurine and hypotaurine metabolism_Homo sapiens_hsa004300.74434189
67Type I diabetes mellitus_Homo sapiens_hsa049400.66207412
68Sphingolipid metabolism_Homo sapiens_hsa006000.65703576
69Glutathione metabolism_Homo sapiens_hsa004800.64848162
70Glycolysis / Gluconeogenesis_Homo sapiens_hsa000100.63811704
71Circadian rhythm_Homo sapiens_hsa047100.62877736
72Fatty acid biosynthesis_Homo sapiens_hsa000610.61684551
73Pentose phosphate pathway_Homo sapiens_hsa000300.56779549
74Butirosin and neomycin biosynthesis_Homo sapiens_hsa005240.54331645
75Mucin type O-Glycan biosynthesis_Homo sapiens_hsa005120.52669186
76Protein export_Homo sapiens_hsa030600.48023529
77Insulin resistance_Homo sapiens_hsa049310.47998883
78Citrate cycle (TCA cycle)_Homo sapiens_hsa000200.47908194
79Graft-versus-host disease_Homo sapiens_hsa053320.45686500
80Cytokine-cytokine receptor interaction_Homo sapiens_hsa040600.42815012
81Regulation of autophagy_Homo sapiens_hsa041400.38669897
82Allograft rejection_Homo sapiens_hsa053300.38473622
83Autoimmune thyroid disease_Homo sapiens_hsa053200.37280091
84Metabolic pathways_Homo sapiens_hsa011000.37087094
85Galactose metabolism_Homo sapiens_hsa000520.36621037
86alpha-Linolenic acid metabolism_Homo sapiens_hsa005920.35072007
87Adipocytokine signaling pathway_Homo sapiens_hsa049200.35028872
88Inflammatory bowel disease (IBD)_Homo sapiens_hsa053210.32999256
89Fructose and mannose metabolism_Homo sapiens_hsa000510.30691342
90Dorso-ventral axis formation_Homo sapiens_hsa043200.28705509
91Hematopoietic cell lineage_Homo sapiens_hsa046400.28181451
92Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.27597472
93Asthma_Homo sapiens_hsa053100.27036601
94Linoleic acid metabolism_Homo sapiens_hsa005910.24916596
95Phototransduction_Homo sapiens_hsa047440.24912011
96Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa049600.24453217
97Renin secretion_Homo sapiens_hsa049240.23943683
98Glycosaminoglycan degradation_Homo sapiens_hsa005310.23195949
99Renin-angiotensin system_Homo sapiens_hsa046140.21438291
100N-Glycan biosynthesis_Homo sapiens_hsa005100.21047742
101Jak-STAT signaling pathway_Homo sapiens_hsa046300.19405718
102Pertussis_Homo sapiens_hsa051330.19097236
103Serotonergic synapse_Homo sapiens_hsa047260.19013743
104Prion diseases_Homo sapiens_hsa050200.14985651
105Glycerophospholipid metabolism_Homo sapiens_hsa005640.14263096
106Protein digestion and absorption_Homo sapiens_hsa049740.14232171
107AMPK signaling pathway_Homo sapiens_hsa041520.14005320
108Carbohydrate digestion and absorption_Homo sapiens_hsa049730.13900261
109Glucagon signaling pathway_Homo sapiens_hsa049220.11742576
110Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.11529950
111Other glycan degradation_Homo sapiens_hsa005110.11059381
112Hepatitis C_Homo sapiens_hsa051600.01386594
113Lysosome_Homo sapiens_hsa041420.00655934
114Thyroid hormone synthesis_Homo sapiens_hsa04918-0.1123589
115Longevity regulating pathway - mammal_Homo sapiens_hsa04211-0.1042908
116Type II diabetes mellitus_Homo sapiens_hsa04930-0.1033253
117Legionellosis_Homo sapiens_hsa05134-0.1012979
118Arachidonic acid metabolism_Homo sapiens_hsa00590-0.0891934
119Pancreatic secretion_Homo sapiens_hsa04972-0.0880246
120Ovarian steroidogenesis_Homo sapiens_hsa04913-0.0830775
121RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622-0.0777121
122Mineral absorption_Homo sapiens_hsa04978-0.0549722
123Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604-0.0439762
124Insulin signaling pathway_Homo sapiens_hsa04910-0.0395490
125Intestinal immune network for IgA production_Homo sapiens_hsa04672-0.0175953
126NF-kappa B signaling pathway_Homo sapiens_hsa04064-0.0112639

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