Rank | Gene Set | Z-score |
---|---|---|
1 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process (GO:1902221) | 5.65216893 |
2 | L-phenylalanine metabolic process (GO:0006558) | 5.65216893 |
3 | L-phenylalanine catabolic process (GO:0006559) | 5.52261379 |
4 | erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process (GO:1902222) | 5.52261379 |
5 | response to pheromone (GO:0019236) | 5.33917658 |
6 | sulfur amino acid catabolic process (GO:0000098) | 5.15269776 |
7 | cysteine metabolic process (GO:0006534) | 4.81874863 |
8 | behavioral response to nicotine (GO:0035095) | 4.70208971 |
9 | aromatic amino acid family catabolic process (GO:0009074) | 4.66679382 |
10 | triglyceride-rich lipoprotein particle remodeling (GO:0034370) | 4.59750030 |
11 | glyoxylate metabolic process (GO:0046487) | 4.57560437 |
12 | alpha-linolenic acid metabolic process (GO:0036109) | 4.55877367 |
13 | homocysteine metabolic process (GO:0050667) | 4.40069024 |
14 | fatty acid beta-oxidation using acyl-CoA oxidase (GO:0033540) | 4.32797124 |
15 | kynurenine metabolic process (GO:0070189) | 4.30027486 |
16 | lysine metabolic process (GO:0006553) | 4.28798333 |
17 | lysine catabolic process (GO:0006554) | 4.28798333 |
18 | valine metabolic process (GO:0006573) | 4.26166219 |
19 | axoneme assembly (GO:0035082) | 4.21966493 |
20 | tryptophan catabolic process (GO:0006569) | 4.09637377 |
21 | indole-containing compound catabolic process (GO:0042436) | 4.09637377 |
22 | indolalkylamine catabolic process (GO:0046218) | 4.09637377 |
23 | bile acid biosynthetic process (GO:0006699) | 4.00403655 |
24 | tryptophan metabolic process (GO:0006568) | 3.97647438 |
25 | serine family amino acid catabolic process (GO:0009071) | 3.92901619 |
26 | branched-chain amino acid catabolic process (GO:0009083) | 3.90989853 |
27 | ethanol oxidation (GO:0006069) | 3.89752693 |
28 | axonemal dynein complex assembly (GO:0070286) | 3.86830156 |
29 | amino-acid betaine metabolic process (GO:0006577) | 3.83890051 |
30 | peptidyl-glutamic acid carboxylation (GO:0017187) | 3.81705893 |
31 | protein carboxylation (GO:0018214) | 3.81705893 |
32 | fatty acid beta-oxidation (GO:0006635) | 3.79932032 |
33 | high-density lipoprotein particle remodeling (GO:0034375) | 3.79025928 |
34 | branched-chain amino acid metabolic process (GO:0009081) | 3.77329897 |
35 | cilium or flagellum-dependent cell motility (GO:0001539) | 3.74032293 |
36 | regulation of triglyceride catabolic process (GO:0010896) | 3.72427840 |
37 | aldehyde catabolic process (GO:0046185) | 3.70848409 |
38 | cornea development in camera-type eye (GO:0061303) | 3.68858230 |
39 | glucuronate metabolic process (GO:0019585) | 3.68021162 |
40 | uronic acid metabolic process (GO:0006063) | 3.68021162 |
41 | 2-oxoglutarate metabolic process (GO:0006103) | 3.66299136 |
42 | xenobiotic catabolic process (GO:0042178) | 3.65512675 |
43 | fatty acid oxidation (GO:0019395) | 3.62270657 |
44 | response to nitrosative stress (GO:0051409) | 3.61909329 |
45 | negative regulation of fibrinolysis (GO:0051918) | 3.60496923 |
46 | base-excision repair, AP site formation (GO:0006285) | 3.59088108 |
47 | glycine metabolic process (GO:0006544) | 3.58935551 |
48 | lipid oxidation (GO:0034440) | 3.56051628 |
49 | protein polyglutamylation (GO:0018095) | 3.54871002 |
50 | regulation of cholesterol esterification (GO:0010872) | 3.53368432 |
51 | cellular modified amino acid catabolic process (GO:0042219) | 3.51931104 |
52 | epithelial cilium movement (GO:0003351) | 3.51855023 |
53 | regulation of cilium movement (GO:0003352) | 3.50599782 |
54 | alpha-amino acid catabolic process (GO:1901606) | 3.50473229 |
55 | cellular amino acid catabolic process (GO:0009063) | 3.49100241 |
56 | complement activation, alternative pathway (GO:0006957) | 3.48154580 |
57 | serine family amino acid metabolic process (GO:0009069) | 3.48100408 |
58 | regulation of fibrinolysis (GO:0051917) | 3.47811327 |
59 | fatty acid catabolic process (GO:0009062) | 3.47435921 |
60 | serine family amino acid biosynthetic process (GO:0009070) | 3.46524049 |
61 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent (G | 3.46437297 |
62 | positive regulation of fatty acid beta-oxidation (GO:0032000) | 3.46233004 |
63 | short-chain fatty acid metabolic process (GO:0046459) | 3.46191571 |
64 | blood coagulation, intrinsic pathway (GO:0007597) | 3.44692418 |
65 | regulation of glucokinase activity (GO:0033131) | 3.43528513 |
66 | regulation of hexokinase activity (GO:1903299) | 3.43528513 |
67 | monocarboxylic acid catabolic process (GO:0072329) | 3.42050127 |
68 | negative regulation of sterol transport (GO:0032372) | 3.41546429 |
69 | negative regulation of cholesterol transport (GO:0032375) | 3.41546429 |
70 | regulation of cholesterol metabolic process (GO:0090181) | 3.39782101 |
71 | reverse cholesterol transport (GO:0043691) | 3.37760196 |
72 | platelet dense granule organization (GO:0060155) | 3.37607191 |
73 | regulation of protein activation cascade (GO:2000257) | 3.35535710 |
74 | carnitine metabolic process (GO:0009437) | 3.35274655 |
75 | cellular glucuronidation (GO:0052695) | 3.35235906 |
76 | bile acid metabolic process (GO:0008206) | 3.34118998 |
77 | carboxylic acid catabolic process (GO:0046395) | 3.33059795 |
78 | organic acid catabolic process (GO:0016054) | 3.33059795 |
79 | aromatic amino acid family metabolic process (GO:0009072) | 3.31989697 |
80 | cilium movement (GO:0003341) | 3.27956512 |
81 | coenzyme catabolic process (GO:0009109) | 3.26809440 |
82 | aspartate family amino acid catabolic process (GO:0009068) | 3.25607270 |
83 | regulation of cholesterol biosynthetic process (GO:0045540) | 3.24005689 |
84 | cell wall macromolecule catabolic process (GO:0016998) | 3.23993332 |
85 | epithelial cilium movement involved in determination of left/right asymmetry (GO:0060287) | 3.22823356 |
86 | negative regulation of lipase activity (GO:0060192) | 3.22810115 |
87 | imidazole-containing compound metabolic process (GO:0052803) | 3.22009027 |
88 | ribosomal small subunit assembly (GO:0000028) | 3.20807695 |
89 | benzene-containing compound metabolic process (GO:0042537) | 3.20763379 |
90 | protein-lipid complex remodeling (GO:0034368) | 3.20594261 |
91 | macromolecular complex remodeling (GO:0034367) | 3.20594261 |
92 | plasma lipoprotein particle remodeling (GO:0034369) | 3.20594261 |
93 | intestinal cholesterol absorption (GO:0030299) | 3.19660027 |
94 | flavonoid metabolic process (GO:0009812) | 3.12692244 |
95 | urea metabolic process (GO:0019627) | 3.10764154 |
96 | urea cycle (GO:0000050) | 3.10764154 |
97 | regulation of plasminogen activation (GO:0010755) | 3.10293470 |
98 | ubiquinone biosynthetic process (GO:0006744) | 3.09472003 |
99 | actin-myosin filament sliding (GO:0033275) | 3.09429476 |
100 | muscle filament sliding (GO:0030049) | 3.09429476 |
101 | L-serine metabolic process (GO:0006563) | 3.08658825 |
102 | regulation of complement activation (GO:0030449) | 3.07067023 |
103 | cellular response to exogenous dsRNA (GO:0071360) | 3.07040020 |
104 | positive regulation of heterotypic cell-cell adhesion (GO:0034116) | 3.06975799 |
105 | regulation of cholesterol homeostasis (GO:2000188) | 3.06226681 |
106 | DNA deamination (GO:0045006) | 3.06022629 |
107 | regulation of sequestering of triglyceride (GO:0010889) | 3.05905494 |
108 | fucose catabolic process (GO:0019317) | 3.05715493 |
109 | L-fucose metabolic process (GO:0042354) | 3.05715493 |
110 | L-fucose catabolic process (GO:0042355) | 3.05715493 |
111 | negative regulation of fatty acid biosynthetic process (GO:0045717) | 3.03179157 |
112 | positive regulation of lipid catabolic process (GO:0050996) | 3.02793434 |
113 | phospholipid efflux (GO:0033700) | 3.02296309 |
114 | triglyceride homeostasis (GO:0070328) | 3.02094312 |
115 | acylglycerol homeostasis (GO:0055090) | 3.02094312 |
116 | regulation of fatty acid beta-oxidation (GO:0031998) | 3.01748364 |
117 | viral transcription (GO:0019083) | 3.01496752 |
118 | translational termination (GO:0006415) | 3.00938208 |
119 | photoreceptor cell development (GO:0042461) | 3.00627798 |
120 | motile cilium assembly (GO:0044458) | 2.98908943 |
121 | positive regulation of histone deacetylation (GO:0031065) | 2.98757182 |
122 | nitrogen cycle metabolic process (GO:0071941) | 2.97799998 |
123 | plasma lipoprotein particle clearance (GO:0034381) | 2.97352962 |
124 | negative regulation of erythrocyte differentiation (GO:0045647) | 2.96336530 |
125 | arginine metabolic process (GO:0006525) | 2.95019627 |
126 | response to mercury ion (GO:0046689) | 2.94427912 |
127 | oxaloacetate metabolic process (GO:0006107) | 2.93871591 |
128 | antigen processing and presentation via MHC class Ib (GO:0002475) | 2.92458223 |
129 | ubiquinone metabolic process (GO:0006743) | 2.86121854 |
130 | detection of light stimulus involved in sensory perception (GO:0050962) | 2.82096883 |
131 | detection of light stimulus involved in visual perception (GO:0050908) | 2.82096883 |
132 | negative regulation of telomere maintenance (GO:0032205) | 2.80026810 |
133 | retinal cone cell development (GO:0046549) | 2.78135239 |
134 | arginine catabolic process (GO:0006527) | 2.78034250 |
135 | positive regulation of defense response to virus by host (GO:0002230) | 2.77597824 |
136 | cell wall macromolecule metabolic process (GO:0044036) | 2.77280987 |
137 | neuronal action potential (GO:0019228) | 2.76469539 |
138 | G-protein coupled glutamate receptor signaling pathway (GO:0007216) | 2.75463321 |
139 | regulation of skeletal muscle contraction (GO:0014819) | 2.75173608 |
140 | negative regulation of synaptic transmission, GABAergic (GO:0032229) | 2.75092417 |
141 | cilium organization (GO:0044782) | 2.66397158 |
142 | water-soluble vitamin biosynthetic process (GO:0042364) | 2.65692160 |
143 | regulation of action potential (GO:0098900) | 2.65498509 |
144 | cilium morphogenesis (GO:0060271) | 2.65463851 |
145 | eye photoreceptor cell development (GO:0042462) | 2.64641522 |
146 | centriole replication (GO:0007099) | 2.64481398 |
147 | negative regulation of mast cell activation (GO:0033004) | 2.64184062 |
148 | detection of mechanical stimulus involved in sensory perception of sound (GO:0050910) | 2.63878942 |
149 | regulation of microtubule-based movement (GO:0060632) | 2.59928337 |
150 | actin-mediated cell contraction (GO:0070252) | 2.59527953 |
151 | regulation of type B pancreatic cell apoptotic process (GO:2000674) | 2.58384274 |
152 | cellular response to ATP (GO:0071318) | 2.58308118 |
153 | regulation of calcineurin-NFAT signaling cascade (GO:0070884) | 2.57032807 |
154 | alanine transport (GO:0032328) | 2.54474912 |
155 | fatty acid transmembrane transport (GO:1902001) | 2.53550683 |
156 | cilium assembly (GO:0042384) | 2.53391276 |
157 | lymphangiogenesis (GO:0001946) | 2.52973968 |
158 | auditory receptor cell stereocilium organization (GO:0060088) | 2.52748866 |
159 | metanephric mesenchyme development (GO:0072075) | 2.52666857 |
160 | positive regulation of cell fate commitment (GO:0010455) | 2.48433761 |
161 | negative regulation of phosphatidylinositol 3-kinase signaling (GO:0014067) | 2.46352864 |
162 | inner ear receptor stereocilium organization (GO:0060122) | 2.45948397 |
163 | peptidyl-histidine modification (GO:0018202) | 2.44305948 |
164 | cellular ketone body metabolic process (GO:0046950) | 2.44264394 |
165 | intraciliary transport (GO:0042073) | 2.43701395 |
166 | photoreceptor cell maintenance (GO:0045494) | 2.42649125 |
167 | negative regulation of reactive oxygen species metabolic process (GO:2000378) | 2.40151108 |
168 | positive regulation of fatty acid oxidation (GO:0046321) | 2.39632495 |
169 | quinone biosynthetic process (GO:1901663) | 2.39210063 |
170 | negative regulation of systemic arterial blood pressure (GO:0003085) | 2.39047224 |
171 | pericardium development (GO:0060039) | 2.37765127 |
172 | N-acetylglucosamine metabolic process (GO:0006044) | 2.36107868 |
173 | cellular component assembly involved in morphogenesis (GO:0010927) | 2.36099039 |
174 | nephron tubule morphogenesis (GO:0072078) | 2.33799278 |
175 | nephron epithelium morphogenesis (GO:0072088) | 2.33799278 |
176 | carnitine transmembrane transport (GO:1902603) | 2.33378480 |
177 | kidney mesenchyme development (GO:0072074) | 2.32486558 |
178 | meiotic chromosome segregation (GO:0045132) | 2.31915066 |
179 | gamma-aminobutyric acid transport (GO:0015812) | 2.31738395 |
180 | exogenous drug catabolic process (GO:0042738) | 2.31699342 |
181 | regulation of hippo signaling (GO:0035330) | 2.28895559 |
182 | organic cation transport (GO:0015695) | 2.28068910 |
183 | reciprocal DNA recombination (GO:0035825) | 2.27632469 |
184 | reciprocal meiotic recombination (GO:0007131) | 2.27632469 |
185 | positive regulation of triglyceride biosynthetic process (GO:0010867) | 2.27618263 |
186 | ketone body metabolic process (GO:1902224) | 2.26781982 |
187 | regulation of triglyceride biosynthetic process (GO:0010866) | 2.26361339 |
188 | negative regulation of protein localization to cell surface (GO:2000009) | 2.26166524 |
189 | estrogen biosynthetic process (GO:0006703) | 2.25674874 |
190 | tachykinin receptor signaling pathway (GO:0007217) | 2.25673016 |
191 | tooth mineralization (GO:0034505) | 2.23746591 |
192 | adenosine metabolic process (GO:0046085) | 2.22456911 |
193 | action potential (GO:0001508) | 2.21547589 |
194 | regulation of vascular endothelial growth factor signaling pathway (GO:1900746) | 2.21474785 |
195 | carnitine shuttle (GO:0006853) | 2.20921922 |
196 | positive regulation of phosphoprotein phosphatase activity (GO:0032516) | 2.20707695 |
197 | membrane depolarization during cardiac muscle cell action potential (GO:0086012) | 2.17922894 |
198 | blood vessel maturation (GO:0001955) | 2.17832918 |
199 | myofibril assembly (GO:0030239) | 2.17152899 |
200 | C4-dicarboxylate transport (GO:0015740) | 2.16582721 |
Rank | Gene Set | Z-score |
---|---|---|
1 | ESR1_17901129_ChIP-ChIP_LIVER_Mouse | 8.50211125 |
2 | PPARG_19300518_ChIP-PET_3T3-L1_Mouse | 5.77938519 |
3 | RXR_22158963_ChIP-Seq_LIVER_Mouse | 5.68784441 |
4 | PPARA_22158963_ChIP-Seq_LIVER_Mouse | 5.04347438 |
5 | EGR1_23403033_ChIP-Seq_LIVER_Mouse | 4.34570765 |
6 | LXR_22158963_ChIP-Seq_LIVER_Mouse | 4.17703063 |
7 | CEBPA_23403033_ChIP-Seq_LIVER_Mouse | 3.61938609 |
8 | FOXO1_23066095_ChIP-Seq_LIVER_Mouse | 3.54291613 |
9 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 3.39572205 |
10 | VDR_22108803_ChIP-Seq_LS180_Human | 3.09930908 |
11 | ZNF274_21170338_ChIP-Seq_K562_Hela | 2.97247737 |
12 | TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse | 2.86450042 |
13 | CEBPB_23403033_ChIP-Seq_LIVER_Mouse | 2.67026957 |
14 | EZH2_22144423_ChIP-Seq_EOC_Human | 2.63413562 |
15 | GBX2_23144817_ChIP-Seq_PC3_Human | 2.60485607 |
16 | IGF1R_20145208_ChIP-Seq_DFB_Human | 2.51847917 |
17 | GLI1_17442700_ChIP-ChIP_MESCs_Mouse | 2.39404200 |
18 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.30219547 |
19 | FLI1_27457419_Chip-Seq_LIVER_Mouse | 2.26140733 |
20 | NR1I2_20693526_ChIP-Seq_LIVER_Mouse | 2.22685278 |
21 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.22354523 |
22 | EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse | 2.19640233 |
23 | GATA2_26923725_Chip-Seq_HEMANGIOBLAST_Mouse | 2.16861800 |
24 | E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse | 2.03168155 |
25 | SCL_19346495_ChIP-Seq_HPC-7_Human | 2.00910562 |
26 | ZFP57_27257070_Chip-Seq_ESCs_Mouse | 2.00388330 |
27 | PCGF2_27294783_Chip-Seq_ESCs_Mouse | 1.99536558 |
28 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.94940230 |
29 | PRDM16_22522345_ChIP-ChIP_PALATE_MESENCHYMAL_Mouse | 1.94451940 |
30 | HNF4A_19761587_ChIP-ChIP_CACO-2_Human | 1.91548176 |
31 | EWS-ERG_20517297_ChIP-Seq_CADO-ES1_Human | 1.89386929 |
32 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.88093859 |
33 | RUNX1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.88063892 |
34 | MYC_18555785_ChIP-Seq_MESCs_Mouse | 1.79940201 |
35 | CTBP2_25329375_ChIP-Seq_LNCAP_Human | 1.78454128 |
36 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.78059198 |
37 | CLOCK_20551151_ChIP-Seq_293T_Human | 1.70273213 |
38 | STAT5_23275557_ChIP-Seq_MAMMARY-EPITHELIUM_Mouse | 1.68216945 |
39 | ER_23166858_ChIP-Seq_MCF-7_Human | 1.65005262 |
40 | STAT3_1855785_ChIP-Seq_MESCs_Mouse | 1.64687529 |
41 | CTBP1_25329375_ChIP-Seq_LNCAP_Human | 1.62503923 |
42 | BCAT_22108803_ChIP-Seq_LS180_Human | 1.61120917 |
43 | ZNF652_21678463_ChIP-ChIP_ZR75-1_Human | 1.56632703 |
44 | THRA_23701648_ChIP-Seq_CEREBELLUM_Mouse | 1.56157434 |
45 | IRF8_22096565_ChIP-ChIP_GC-B_Human | 1.55003834 |
46 | EED_16625203_ChIP-ChIP_MESCs_Mouse | 1.52244223 |
47 | NR3C1_21868756_ChIP-Seq_MCF10A_Human | 1.48823872 |
48 | PAX3-FKHR_20663909_ChIP-Seq_RHABDOMYOSARCOMA_Human | 1.47809315 |
49 | PCGF2_27294783_Chip-Seq_NPCs_Mouse | 1.45392327 |
50 | EWS-FLI1_20517297_ChIP-Seq_SK-N-MC_Human | 1.44711565 |
51 | P300_19829295_ChIP-Seq_ESCs_Human | 1.44063128 |
52 | AUTS2_25519132_ChIP-Seq_293T-REX_Human | 1.41028307 |
53 | DROSHA_22980978_ChIP-Seq_HELA_Human | 1.40461730 |
54 | ETV2_25802403_ChIP-Seq_MESCs_Mouse | 1.40036207 |
55 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.38290684 |
56 | POU3F2_20337985_ChIP-ChIP_501MEL_Human | 1.37145688 |
57 | EWS_26573619_Chip-Seq_HEK293_Human | 1.36133955 |
58 | MYC_20876797_ChIP-ChIP_MEDULLOBLASTOMA_Human | 1.35953068 |
59 | TCF7L2_21901280_ChIP-Seq_H4IIE_Rat | 1.35934596 |
60 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.32969944 |
61 | SMAD4_21799915_ChIP-Seq_A2780_Human | 1.32322980 |
62 | TBP_23326641_ChIP-Seq_C3H10T1-2_Mouse | 1.31414755 |
63 | STAT3_23295773_ChIP-Seq_U87_Human | 1.30837822 |
64 | RUNX1_20887958_ChIP-Seq_HPC-7_Mouse | 1.30695545 |
65 | NANOG_20526341_ChIP-Seq_ESCs_Human | 1.29390656 |
66 | SMAD4_21741376_ChIP-Seq_EPCs_Human | 1.29218954 |
67 | TCF4_23295773_ChIP-Seq_U87_Human | 1.28589898 |
68 | SMAD2/3_21741376_ChIP-Seq_EPCs_Human | 1.27266609 |
69 | NANOG_19829295_ChIP-Seq_ESCs_Human | 1.26587696 |
70 | SOX2_19829295_ChIP-Seq_ESCs_Human | 1.26587696 |
71 | NR1H3_23393188_ChIP-Seq_ATHEROSCLEROTIC-FOAM_Human | 1.24915169 |
72 | CBP_20019798_ChIP-Seq_JUKART_Human | 1.24130704 |
73 | IRF4_20064451_ChIP-Seq_CD4+T_Mouse | 1.24130704 |
74 | FUS_26573619_Chip-Seq_HEK293_Human | 1.22733893 |
75 | NCOR_22424771_ChIP-Seq_293T_Human | 1.22680240 |
76 | CJUN_26792858_Chip-Seq_BT549_Human | 1.21722775 |
77 | IRF1_21803131_ChIP-Seq_MONOCYTES_Human | 1.21535766 |
78 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.20883963 |
79 | TOP2B_26459242_ChIP-Seq_MCF-7_Human | 1.20108330 |
80 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 1.19832821 |
81 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.18752570 |
82 | * TP53_22573176_ChIP-Seq_HFKS_Human | 1.17769385 |
83 | TCF4_22108803_ChIP-Seq_LS180_Human | 1.17352834 |
84 | HOXB7_26014856_ChIP-Seq_BT474_Human | 1.16884275 |
85 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.16784504 |
86 | SUZ12_18692474_ChIP-Seq_MESCs_Mouse | 1.16661630 |
87 | KLF5_20875108_ChIP-Seq_MESCs_Mouse | 1.16648116 |
88 | CHD7_19251738_ChIP-ChIP_MESCs_Mouse | 1.16643718 |
89 | BACH1_22875853_ChIP-PCR_HELA_AND_SCP4_Human | 1.16177568 |
90 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.15481047 |
91 | TAL1_26923725_Chip-Seq_MACROPHAGESS_Mouse | 1.15354191 |
92 | FOXA1_27270436_Chip-Seq_PROSTATE_Human | 1.15218943 |
93 | FOXA1_25329375_ChIP-Seq_VCAP_Human | 1.15218943 |
94 | TAL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.14491049 |
95 | SUZ12_27294783_Chip-Seq_NPCs_Mouse | 1.14448074 |
96 | HOXC9_25013753_ChIP-Seq_NEUROBLASTOMA_BE2-C_Human | 1.13967558 |
97 | UBF1/2_26484160_Chip-Seq_FIBROBLAST_Human | 1.13419216 |
98 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.13276511 |
99 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.13184834 |
100 | LYL1_20887958_ChIP-Seq_HPC-7_Mouse | 1.13095122 |
101 | LXR_22292898_ChIP-Seq_THP-1_Human | 1.12708596 |
102 | NR0B1_18358816_ChIP-ChIP_MESCs_Mouse | 1.12060235 |
103 | CEBPA_26348894_ChIP-Seq_LIVER_Mouse | 1.12021433 |
104 | CBX2_27304074_Chip-Seq_ESCs_Mouse | 1.12013262 |
105 | GRHL2_25758223_ChIP-Seq_PLACENTA_Mouse | 1.11823778 |
106 | GATA3_21878914_ChIP-Seq_MCF-7_Human | 1.11432201 |
107 | MYC_18358816_ChIP-ChIP_MESCs_Mouse | 1.11292473 |
108 | RAD21_21589869_ChIP-Seq_MESCs_Mouse | 1.08958703 |
109 | E2F1_18555785_ChIP-Seq_MESCs_Mouse | 1.08841864 |
110 | ERA_21632823_ChIP-Seq_H3396_Human | 1.07046092 |
111 | TDRD3_21172665_ChIP-Seq_MCF-7_Human | 1.06906040 |
112 | MYC_19829295_ChIP-Seq_ESCs_Human | 1.06658579 |
113 | SUZ12_16625203_ChIP-ChIP_MESCs_Mouse | 1.06226687 |
114 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 1.06119269 |
115 | AR_25329375_ChIP-Seq_VCAP_Human | 1.06097179 |
116 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.05117480 |
117 | NFE2_27457419_Chip-Seq_LIVER_Mouse | 1.04460496 |
118 | RXR_22108803_ChIP-Seq_LS180_Human | 1.04375594 |
119 | CEBPB_24764292_ChIP-Seq_MC3T3_Mouse | 1.04162451 |
120 | EZH2_27294783_Chip-Seq_NPCs_Mouse | 1.03664534 |
121 | * ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.03347601 |
122 | GATA1_22025678_ChIP-Seq_K562_Human | 1.02542225 |
123 | P53_21459846_ChIP-Seq_SAOS-2_Human | 1.02223437 |
124 | GATA4_25053715_ChIP-Seq_YYC3_Human | 1.01945959 |
125 | BMI1_23680149_ChIP-Seq_NPCS_Mouse | 1.01065338 |
126 | RUNX2_22187159_ChIP-Seq_PCA_Human | 1.00647069 |
127 | * SUZ12_20075857_ChIP-Seq_MESCs_Mouse | 1.00010171 |
128 | GATA1_22383799_ChIP-Seq_G1ME_Mouse | 0.99888452 |
129 | BMI1_19503595_ChIP-Seq_MEFsC_Mouse | 0.99457725 |
130 | EZH2_27294783_Chip-Seq_ESCs_Mouse | 0.99288282 |
131 | IRF8_22096565_ChIP-ChIP_GC-B_Mouse | 0.99030138 |
132 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 0.98959249 |
133 | CDX2_22108803_ChIP-Seq_LS180_Human | 0.98590328 |
134 | SUZ12_18692474_ChIP-Seq_MEFs_Mouse | 0.97418482 |
135 | SMARCD1_25818293_ChIP-Seq_ESCs_Mouse | 0.97168063 |
136 | IKZF1_21737484_ChIP-ChIP_HCT116_Human | 0.97117293 |
137 | * PBX1_22567123_ChIP-ChIP_OVCAR3_Human | 0.97020217 |
138 | SMAD3_21741376_ChIP-Seq_EPCs_Human | 0.96964395 |
139 | GATA2_20887958_ChIP-Seq_HPC-7_Mouse | 0.96871480 |
140 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 0.96814360 |
141 | ESRRB_18555785_ChIP-Seq_MESCs_Mouse | 0.96231878 |
142 | FOXH1_21741376_ChIP-Seq_EPCs_Human | 0.96221610 |
143 | TAF2_19829295_ChIP-Seq_ESCs_Human | 0.96198890 |
144 | FOXH1_21741376_ChIP-Seq_ESCs_Human | 0.95982421 |
145 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 0.95951721 |
146 | SOX2_18692474_ChIP-Seq_MEFs_Mouse | 0.95574120 |
147 | MEIS1_26253404_ChIP-Seq_OPTIC_CUPS_Mouse | 0.95441044 |
148 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 0.95335346 |
149 | HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse | 0.95178889 |
150 | AHR_22903824_ChIP-Seq_MCF-7_Human | 0.94667441 |
151 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 0.94523602 |
152 | RXRA_24833708_ChIP-Seq_LIVER_Mouse | 0.92973341 |
153 | ERG_20887958_ChIP-Seq_HPC-7_Mouse | 0.91333403 |
154 | SOX2_27498859_Chip-Seq_STOMACH_Mouse | 0.90894970 |
155 | FLI1_20887958_ChIP-Seq_HPC-7_Mouse | 0.90752584 |
156 | P63_26484246_Chip-Seq_KERATINOCYTES_Human | 0.90176556 |
157 | * CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 0.87840367 |
158 | SRF_21415370_ChIP-Seq_HL-1_Mouse | 0.87141174 |
159 | * ELK3_25401928_ChIP-Seq_HUVEC_Human | 0.85162509 |
160 | GATA2_22383799_ChIP-Seq_G1ME_Mouse | 0.84584754 |
161 | SREBP1_19666523_ChIP-Seq_LIVER_Mouse | 0.84445710 |
162 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 0.84032926 |
163 | ELF1_17652178_ChIP-ChIP_JURKAT_Human | 0.83099896 |
164 | BCL3_23251550_ChIP-Seq_MUSCLE_Mouse | 0.82132501 |
165 | * BCL6_27268052_Chip-Seq_Bcells_Human | 0.81855256 |
166 | CTCF_21964334_Chip-Seq_Bcells_Human | 0.81843129 |
167 | OCT4_18692474_ChIP-Seq_MEFs_Mouse | 0.80921492 |
168 | SREBP2_21459322_ChIP-Seq_LIVER_Mouse | 0.79076355 |
169 | SPI1_22790984_ChIP-Seq_ERYTHROLEUKEMIA_Mouse | 0.78716439 |
170 | RELA_24523406_ChIP-Seq_FIBROSARCOMA_Human | 0.77516881 |
171 | TAL1_20566737_ChIP-Seq_PRIMARY_FETAL_LIVER_ERYTHROID_Mouse | 0.76317009 |
172 | GATA6_25053715_ChIP-Seq_YYC3_Human | 0.76042709 |
173 | PPARD_23208498_ChIP-Seq_MDA-MB-231_Human | 0.74756633 |
174 | TET1_21451524_ChIP-Seq_MESCs_Mouse | 0.74212037 |
175 | SRY_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.73769166 |
176 | BP1_19119308_ChIP-ChIP_Hs578T_Human | 0.73607925 |
177 | GATA1_19941827_ChIP-Seq_MEL_Mouse | 0.73026307 |
178 | CTCF_21964334_ChIP-Seq_BJAB-B_Human | 0.71685587 |
179 | HNF4A_19822575_ChIP-Seq_HepG2_Human | 0.71354809 |
180 | LMO2_20887958_ChIP-Seq_HPC-7_Mouse | 0.71270570 |
181 | SOX9_25088423_ChIP-ChIP_EMBRYONIC_GONADS_Mouse | 0.71048069 |
182 | NKX2-5_21415370_ChIP-Seq_HL-1_Mouse | 0.70747808 |
183 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.70715367 |
184 | * TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.70522187 |
185 | MYC_19030024_ChIP-ChIP_MESCs_Mouse | 0.69744560 |
186 | AR_20517297_ChIP-Seq_VCAP_Human | 0.69159997 |
187 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.69076579 |
188 | CTCF_18555785_ChIP-Seq_MESCs_Mouse | 0.68814563 |
189 | MYB_21317192_ChIP-Seq_ERMYB_Mouse | 0.68749235 |
190 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 0.68619244 |
191 | FOXA2_19822575_ChIP-Seq_HepG2_Human | 0.68436619 |
192 | SPI1_20517297_ChIP-Seq_HL60_Human | 0.68300365 |
193 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 0.67919493 |
194 | * CUX1_19635798_ChIP-ChIP_MULTIPLE_HUMAN_CANCER_TYPES_Human | 0.67466471 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0002139_abnormal_hepatobiliary_system | 6.01082390 |
2 | MP0005365_abnormal_bile_salt | 4.96374383 |
3 | MP0005085_abnormal_gallbladder_physiolo | 4.92573834 |
4 | MP0005360_urolithiasis | 4.73475793 |
5 | MP0008875_abnormal_xenobiotic_pharmacok | 3.66686022 |
6 | MP0003806_abnormal_nucleotide_metabolis | 3.59582527 |
7 | MP0010329_abnormal_lipoprotein_level | 2.86110067 |
8 | MP0003252_abnormal_bile_duct | 2.77953638 |
9 | MP0009840_abnormal_foam_cell | 2.69526491 |
10 | MP0005083_abnormal_biliary_tract | 2.51086444 |
11 | MP0001666_abnormal_nutrient_absorption | 2.40727821 |
12 | MP0000372_irregular_coat_pigmentation | 2.27627665 |
13 | MP0003186_abnormal_redox_activity | 2.22146258 |
14 | MP0005332_abnormal_amino_acid | 2.20893948 |
15 | MP0005503_abnormal_tendon_morphology | 2.11451439 |
16 | MP0008775_abnormal_heart_ventricle | 2.08111498 |
17 | MP0005551_abnormal_eye_electrophysiolog | 2.01897822 |
18 | MP0008789_abnormal_olfactory_epithelium | 1.98737271 |
19 | MP0003195_calcinosis | 1.97692308 |
20 | MP0005319_abnormal_enzyme/_coenzyme | 1.95956358 |
21 | MP0004084_abnormal_cardiac_muscle | 1.91010387 |
22 | MP0004885_abnormal_endolymph | 1.88099266 |
23 | MP0003136_yellow_coat_color | 1.87714049 |
24 | MP0002638_abnormal_pupillary_reflex | 1.85875999 |
25 | MP0005257_abnormal_intraocular_pressure | 1.82898243 |
26 | MP0003656_abnormal_erythrocyte_physiolo | 1.80567454 |
27 | MP0004036_abnormal_muscle_relaxation | 1.77198733 |
28 | MP0003011_delayed_dark_adaptation | 1.75905647 |
29 | MP0000609_abnormal_liver_physiology | 1.72944712 |
30 | MP0008438_abnormal_cutaneous_collagen | 1.72530232 |
31 | MP0008872_abnormal_physiological_respon | 1.68520258 |
32 | MP0005646_abnormal_pituitary_gland | 1.66377872 |
33 | MP0002118_abnormal_lipid_homeostasis | 1.64962621 |
34 | MP0009780_abnormal_chondrocyte_physiolo | 1.64578226 |
35 | MP0004130_abnormal_muscle_cell | 1.63285209 |
36 | MP0004215_abnormal_myocardial_fiber | 1.60418955 |
37 | MP0002653_abnormal_ependyma_morphology | 1.59401040 |
38 | MP0006292_abnormal_olfactory_placode | 1.56457270 |
39 | MP0003705_abnormal_hypodermis_morpholog | 1.53732987 |
40 | MP0002102_abnormal_ear_morphology | 1.52190551 |
41 | MP0002138_abnormal_hepatobiliary_system | 1.50692471 |
42 | MP0001968_abnormal_touch/_nociception | 1.50577789 |
43 | MP0002837_dystrophic_cardiac_calcinosis | 1.49691898 |
44 | MP0006036_abnormal_mitochondrial_physio | 1.48843372 |
45 | MP0004142_abnormal_muscle_tone | 1.48049109 |
46 | MP0002938_white_spotting | 1.43325364 |
47 | MP0005220_abnormal_exocrine_pancreas | 1.42961375 |
48 | MP0010386_abnormal_urinary_bladder | 1.42215598 |
49 | MP0002736_abnormal_nociception_after | 1.42120342 |
50 | MP0003950_abnormal_plasma_membrane | 1.38354965 |
51 | MP0005620_abnormal_muscle_contractility | 1.37903037 |
52 | MP0002735_abnormal_chemical_nociception | 1.37729024 |
53 | MP0005670_abnormal_white_adipose | 1.36523611 |
54 | MP0009643_abnormal_urine_homeostasis | 1.36324969 |
55 | MP0003191_abnormal_cellular_cholesterol | 1.35783912 |
56 | MP0004133_heterotaxia | 1.34676251 |
57 | MP0005584_abnormal_enzyme/coenzyme_acti | 1.33837630 |
58 | MP0000516_abnormal_urinary_system | 1.33822854 |
59 | MP0005367_renal/urinary_system_phenotyp | 1.33822854 |
60 | MP0003868_abnormal_feces_composition | 1.33740364 |
61 | MP0008877_abnormal_DNA_methylation | 1.32558645 |
62 | MP0009384_cardiac_valve_regurgitation | 1.32525057 |
63 | MP0001348_abnormal_lacrimal_gland | 1.30382880 |
64 | MP0002160_abnormal_reproductive_system | 1.27592851 |
65 | MP0004019_abnormal_vitamin_homeostasis | 1.24046600 |
66 | MP0009697_abnormal_copulation | 1.23991841 |
67 | MP0004484_altered_response_of | 1.23647554 |
68 | MP0000013_abnormal_adipose_tissue | 1.23206945 |
69 | MP0000598_abnormal_liver_morphology | 1.22550049 |
70 | MP0004147_increased_porphyrin_level | 1.21314866 |
71 | MP0005171_absent_coat_pigmentation | 1.21153001 |
72 | MP0005410_abnormal_fertilization | 1.20934805 |
73 | MP0005084_abnormal_gallbladder_morpholo | 1.19087943 |
74 | MP0002254_reproductive_system_inflammat | 1.18827058 |
75 | MP0005666_abnormal_adipose_tissue | 1.18034486 |
76 | MP0009046_muscle_twitch | 1.15798300 |
77 | MP0001542_abnormal_bone_strength | 1.15559700 |
78 | MP0000003_abnormal_adipose_tissue | 1.13413705 |
79 | MP0009764_decreased_sensitivity_to | 1.11432737 |
80 | MP0001502_abnormal_circadian_rhythm | 1.08690296 |
81 | MP0005253_abnormal_eye_physiology | 1.06983661 |
82 | MP0001958_emphysema | 1.05267280 |
83 | MP0008469_abnormal_protein_level | 1.05223222 |
84 | MP0006072_abnormal_retinal_apoptosis | 1.03089441 |
85 | MP0001501_abnormal_sleep_pattern | 1.01168899 |
86 | MP0000049_abnormal_middle_ear | 1.01033659 |
87 | MP0001545_abnormal_hematopoietic_system | 0.99932489 |
88 | MP0005397_hematopoietic_system_phenotyp | 0.99932489 |
89 | MP0002877_abnormal_melanocyte_morpholog | 0.99630507 |
90 | MP0002972_abnormal_cardiac_muscle | 0.99308649 |
91 | MP0002249_abnormal_larynx_morphology | 0.99044711 |
92 | MP0002108_abnormal_muscle_morphology | 0.98647520 |
93 | MP0000230_abnormal_systemic_arterial | 0.98459459 |
94 | MP0002272_abnormal_nervous_system | 0.97621006 |
95 | MP0005636_abnormal_mineral_homeostasis | 0.94567075 |
96 | MP0005647_abnormal_sex_gland | 0.94407092 |
97 | MP0005174_abnormal_tail_pigmentation | 0.94025763 |
98 | MP0004085_abnormal_heartbeat | 0.93257406 |
99 | MP0009745_abnormal_behavioral_response | 0.92556272 |
100 | MP0005389_reproductive_system_phenotype | 0.91754163 |
101 | MP0006276_abnormal_autonomic_nervous | 0.91739982 |
102 | MP0003638_abnormal_response/metabolism_ | 0.90412222 |
103 | MP0003567_abnormal_fetal_cardiomyocyte | 0.90248366 |
104 | MP0005266_abnormal_metabolism | 0.90028543 |
105 | MP0000749_muscle_degeneration | 0.89863527 |
106 | MP0001984_abnormal_olfaction | 0.89634640 |
107 | MP0003137_abnormal_impulse_conducting | 0.89565010 |
108 | MP0002127_abnormal_cardiovascular_syste | 0.88550440 |
109 | MP0009763_increased_sensitivity_to | 0.87328253 |
110 | MP0009250_abnormal_appendicular_skeleto | 0.87327419 |
111 | MP0002106_abnormal_muscle_physiology | 0.86461913 |
112 | MP0001661_extended_life_span | 0.86204769 |
113 | MP0005330_cardiomyopathy | 0.85650555 |
114 | MP0000427_abnormal_hair_cycle | 0.85364630 |
115 | MP0005369_muscle_phenotype | 0.85167154 |
116 | MP0001986_abnormal_taste_sensitivity | 0.83991935 |
117 | MP0009642_abnormal_blood_homeostasis | 0.83934205 |
118 | MP0005464_abnormal_platelet_physiology | 0.82478779 |
119 | MP0003646_muscle_fatigue | 0.81014131 |
120 | MP0002295_abnormal_pulmonary_circulatio | 0.80961708 |
121 | MP0002078_abnormal_glucose_homeostasis | 0.79635320 |
122 | MP0005394_taste/olfaction_phenotype | 0.78830319 |
123 | MP0005499_abnormal_olfactory_system | 0.78830319 |
124 | MP0001485_abnormal_pinna_reflex | 0.78487422 |
125 | MP0000613_abnormal_salivary_gland | 0.78265846 |
126 | MP0000678_abnormal_parathyroid_gland | 0.78221749 |
127 | MP0000685_abnormal_immune_system | 0.77148908 |
128 | MP0001529_abnormal_vocalization | 0.76881654 |
129 | MP0010368_abnormal_lymphatic_system | 0.76257959 |
130 | MP0005195_abnormal_posterior_eye | 0.76135162 |
131 | MP0001970_abnormal_pain_threshold | 0.75483111 |
132 | MP0000747_muscle_weakness | 0.75117431 |
133 | MP0004043_abnormal_pH_regulation | 0.74406498 |
134 | MP0000343_altered_response_to | 0.74269649 |
135 | MP0005023_abnormal_wound_healing | 0.73766026 |
136 | MP0005508_abnormal_skeleton_morphology | 0.73525466 |
137 | MP0001270_distended_abdomen | 0.73486798 |
138 | MP0004782_abnormal_surfactant_physiolog | 0.73475457 |
139 | MP0003279_aneurysm | 0.72654900 |
140 | MP0000759_abnormal_skeletal_muscle | 0.72498984 |
141 | MP0001764_abnormal_homeostasis | 0.72439102 |
142 | MP0002796_impaired_skin_barrier | 0.71264082 |
143 | MP0002009_preneoplasia | 0.70832876 |
144 | MP0002269_muscular_atrophy | 0.70296072 |
145 | MP0001853_heart_inflammation | 0.69616799 |
146 | MP0006054_spinal_hemorrhage | 0.69006480 |
147 | MP0000751_myopathy | 0.69006169 |
148 | MP0002971_abnormal_brown_adipose | 0.68668023 |
149 | MP0009785_altered_susceptibility_to | 0.68650898 |
150 | MP0005334_abnormal_fat_pad | 0.68166498 |
151 | MP0000383_abnormal_hair_follicle | 0.66337292 |
152 | MP0010030_abnormal_orbit_morphology | 0.65156480 |
153 | MP0009379_abnormal_foot_pigmentation | 0.64750338 |
154 | MP0005375_adipose_tissue_phenotype | 0.64731529 |
155 | MP0010630_abnormal_cardiac_muscle | 0.64565658 |
156 | MP0002098_abnormal_vibrissa_morphology | 0.64490164 |
157 | MP0003943_abnormal_hepatobiliary_system | 0.64095122 |
158 | MP0003566_abnormal_cell_adhesion | 0.63508714 |
159 | MP0002060_abnormal_skin_morphology | 0.63336789 |
160 | MP0004808_abnormal_hematopoietic_stem | 0.62336091 |
161 | MP0004087_abnormal_muscle_fiber | 0.60467694 |
162 | MP0001944_abnormal_pancreas_morphology | 0.58913820 |
163 | MP0002876_abnormal_thyroid_physiology | 0.57566306 |
164 | MP0001879_abnormal_lymphatic_vessel | 0.57144697 |
165 | MP0005385_cardiovascular_system_phenoty | 0.56922333 |
166 | MP0001544_abnormal_cardiovascular_syste | 0.56922333 |
167 | MP0005275_abnormal_skin_tensile | 0.56779936 |
168 | MP0000750_abnormal_muscle_regeneration | 0.56563820 |
169 | MP0008004_abnormal_stomach_pH | 0.56365137 |
170 | MP0004145_abnormal_muscle_electrophysio | 0.56090554 |
171 | MP0009765_abnormal_xenobiotic_induced | 0.55547085 |
172 | MP0003221_abnormal_cardiomyocyte_apopto | 0.55410904 |
173 | MP0004185_abnormal_adipocyte_glucose | 0.55002279 |
174 | MP0003453_abnormal_keratinocyte_physiol | 0.54747864 |
175 | MP0006138_congestive_heart_failure | 0.54456632 |
176 | MP0005248_abnormal_Harderian_gland | 0.54345966 |
177 | MP0006035_abnormal_mitochondrial_morpho | 0.53770361 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Abnormality of aromatic amino acid family metabolism (HP:0004338) | 5.49811311 |
2 | Intrahepatic cholestasis (HP:0001406) | 5.03117231 |
3 | Deep venous thrombosis (HP:0002625) | 4.92743889 |
4 | Abnormality of monocarboxylic acid metabolism (HP:0010996) | 4.34555780 |
5 | Ketosis (HP:0001946) | 4.32693268 |
6 | Pancreatic fibrosis (HP:0100732) | 4.27502135 |
7 | Hypoglycemic coma (HP:0001325) | 4.11907585 |
8 | Xanthomatosis (HP:0000991) | 4.09453006 |
9 | True hermaphroditism (HP:0010459) | 4.04010693 |
10 | Congenital stationary night blindness (HP:0007642) | 4.01712070 |
11 | Abnormality of long-chain fatty-acid metabolism (HP:0010964) | 4.00360406 |
12 | Dynein arm defect of respiratory motile cilia (HP:0012255) | 3.99023157 |
13 | Absent/shortened dynein arms (HP:0200106) | 3.99023157 |
14 | Hypobetalipoproteinemia (HP:0003563) | 3.91147920 |
15 | Hyperlipoproteinemia (HP:0010980) | 3.87832905 |
16 | Hyperammonemia (HP:0001987) | 3.86023163 |
17 | Hyperglycinemia (HP:0002154) | 3.82118817 |
18 | Abnormality of fatty-acid metabolism (HP:0004359) | 3.81546125 |
19 | Pancreatic cysts (HP:0001737) | 3.74628985 |
20 | Molar tooth sign on MRI (HP:0002419) | 3.71841307 |
21 | Abnormality of midbrain morphology (HP:0002418) | 3.71841307 |
22 | Prolonged partial thromboplastin time (HP:0003645) | 3.70827053 |
23 | Abnormal respiratory motile cilium morphology (HP:0005938) | 3.69020995 |
24 | Abnormal respiratory epithelium morphology (HP:0012253) | 3.69020995 |
25 | Hyperglycinuria (HP:0003108) | 3.66678018 |
26 | Abnormality of glycine metabolism (HP:0010895) | 3.59579965 |
27 | Abnormality of serine family amino acid metabolism (HP:0010894) | 3.59579965 |
28 | Ketoacidosis (HP:0001993) | 3.59441680 |
29 | Keratoconus (HP:0000563) | 3.31313764 |
30 | Increased corneal curvature (HP:0100692) | 3.31313764 |
31 | Dicarboxylic aciduria (HP:0003215) | 3.29092582 |
32 | Abnormality of dicarboxylic acid metabolism (HP:0010995) | 3.29092582 |
33 | Abnormality of the common coagulation pathway (HP:0010990) | 3.26221034 |
34 | Abnormal rod and cone electroretinograms (HP:0008323) | 3.22104000 |
35 | Type 1 muscle fiber predominance (HP:0003803) | 3.19871738 |
36 | Type II lissencephaly (HP:0007260) | 3.18795635 |
37 | Fat malabsorption (HP:0002630) | 3.18671959 |
38 | Abnormal ciliary motility (HP:0012262) | 3.17011266 |
39 | Abnormality of the intrinsic pathway (HP:0010989) | 3.14171626 |
40 | Aplastic anemia (HP:0001915) | 3.13308791 |
41 | Nephronophthisis (HP:0000090) | 3.11620869 |
42 | Abnormality of sulfur amino acid metabolism (HP:0004339) | 3.09403395 |
43 | Abnormal respiratory motile cilium physiology (HP:0012261) | 3.02928552 |
44 | Hypolipoproteinemia (HP:0010981) | 3.01087918 |
45 | Respiratory insufficiency due to defective ciliary clearance (HP:0200073) | 2.94298991 |
46 | Decreased central vision (HP:0007663) | 2.88976452 |
47 | Abnormality of serum amino acid levels (HP:0003112) | 2.86178863 |
48 | Medial flaring of the eyebrow (HP:0010747) | 2.83587024 |
49 | Hypoplasia of the fovea (HP:0007750) | 2.82603966 |
50 | Aplasia/Hypoplasia of the fovea (HP:0008060) | 2.82603966 |
51 | Attenuation of retinal blood vessels (HP:0007843) | 2.81917172 |
52 | Abnormality of the level of lipoprotein cholesterol (HP:0010979) | 2.80053916 |
53 | Spontaneous abortion (HP:0005268) | 2.78961670 |
54 | Abnormality of the renal cortex (HP:0011035) | 2.78644929 |
55 | Steatorrhea (HP:0002570) | 2.76321936 |
56 | Cerebral edema (HP:0002181) | 2.76281860 |
57 | Myoglobinuria (HP:0002913) | 2.75653982 |
58 | Generalized aminoaciduria (HP:0002909) | 2.75471742 |
59 | Hyperbilirubinemia (HP:0002904) | 2.74222420 |
60 | Hypoalphalipoproteinemia (HP:0003233) | 2.73547294 |
61 | Joint hemorrhage (HP:0005261) | 2.72893752 |
62 | Cystic liver disease (HP:0006706) | 2.70528742 |
63 | Abnormality of the renal medulla (HP:0100957) | 2.69107660 |
64 | Abnormality of aspartate family amino acid metabolism (HP:0010899) | 2.68741957 |
65 | Complement deficiency (HP:0004431) | 2.68625303 |
66 | Abnormality of methionine metabolism (HP:0010901) | 2.67256279 |
67 | Sclerocornea (HP:0000647) | 2.66121741 |
68 | Metabolic acidosis (HP:0001942) | 2.64930712 |
69 | Rhinitis (HP:0012384) | 2.64732304 |
70 | Tubular atrophy (HP:0000092) | 2.63647643 |
71 | Lethargy (HP:0001254) | 2.63597046 |
72 | Absent rod-and cone-mediated responses on ERG (HP:0007688) | 2.60823699 |
73 | Abnormality of glutamine family amino acid metabolism (HP:0010902) | 2.59069261 |
74 | Hypoglycemic seizures (HP:0002173) | 2.58559826 |
75 | Hepatic necrosis (HP:0002605) | 2.56223378 |
76 | Delayed CNS myelination (HP:0002188) | 2.55263217 |
77 | Aplasia/Hypoplasia of the tongue (HP:0010295) | 2.54556370 |
78 | Spastic diplegia (HP:0001264) | 2.54463779 |
79 | Follicular hyperkeratosis (HP:0007502) | 2.49855193 |
80 | Increased muscle lipid content (HP:0009058) | 2.48956771 |
81 | Hypercholesterolemia (HP:0003124) | 2.48857206 |
82 | Muscle fiber inclusion bodies (HP:0100299) | 2.46093028 |
83 | Abnormality of macular pigmentation (HP:0008002) | 2.45976363 |
84 | Anencephaly (HP:0002323) | 2.38856077 |
85 | Muscle fiber cytoplasmatic inclusion bodies (HP:0100303) | 2.37482665 |
86 | Redundant skin (HP:0001582) | 2.33661739 |
87 | Hyperinsulinemic hypoglycemia (HP:0000825) | 2.32433604 |
88 | Abnormality of the heme biosynthetic pathway (HP:0010472) | 2.32162119 |
89 | Occipital encephalocele (HP:0002085) | 2.31069788 |
90 | Postaxial foot polydactyly (HP:0001830) | 2.30653745 |
91 | Calf muscle hypertrophy (HP:0008981) | 2.30104417 |
92 | Large for gestational age (HP:0001520) | 2.29894167 |
93 | Right ventricular cardiomyopathy (HP:0011663) | 2.29764796 |
94 | Congenital hepatic fibrosis (HP:0002612) | 2.29590020 |
95 | Gait imbalance (HP:0002141) | 2.25340791 |
96 | Abnormality of the fovea (HP:0000493) | 2.24450340 |
97 | Methylmalonic aciduria (HP:0012120) | 2.24123323 |
98 | Epidermoid cyst (HP:0200040) | 2.23580733 |
99 | Abolished electroretinogram (ERG) (HP:0000550) | 2.22278133 |
100 | Hip contracture (HP:0003273) | 2.22125478 |
101 | Gout (HP:0001997) | 2.21848180 |
102 | Pendular nystagmus (HP:0012043) | 2.20735502 |
103 | Distal arthrogryposis (HP:0005684) | 2.20321014 |
104 | Abnormality of purine metabolism (HP:0004352) | 2.20274220 |
105 | Decreased electroretinogram (ERG) amplitude (HP:0000654) | 2.20043386 |
106 | Thrombocytosis (HP:0001894) | 2.19984003 |
107 | Brushfield spots (HP:0001088) | 2.18666934 |
108 | Nemaline bodies (HP:0003798) | 2.18381495 |
109 | Vascular calcification (HP:0004934) | 2.18364953 |
110 | Abnormality of nucleobase metabolism (HP:0010932) | 2.17244253 |
111 | Left ventricular hypertrophy (HP:0001712) | 2.16025138 |
112 | Increased intramyocellular lipid droplets (HP:0012240) | 2.15925047 |
113 | Increased serum ferritin (HP:0003281) | 2.14912940 |
114 | Congenital primary aphakia (HP:0007707) | 2.14821120 |
115 | Opisthotonus (HP:0002179) | 2.14109641 |
116 | Late onset (HP:0003584) | 2.13125654 |
117 | Esophageal varix (HP:0002040) | 2.11382207 |
118 | Abnormality of pyrimidine metabolism (HP:0004353) | 2.11184321 |
119 | Neonatal onset (HP:0003623) | 2.11013164 |
120 | Conjugated hyperbilirubinemia (HP:0002908) | 2.10895355 |
121 | Abnormality of the calf musculature (HP:0001430) | 2.07587647 |
122 | Abnormal hemoglobin (HP:0011902) | 2.07527754 |
123 | Nephrogenic diabetes insipidus (HP:0009806) | 2.06858952 |
124 | Polycythemia (HP:0001901) | 2.06103171 |
125 | Abnormality of iron homeostasis (HP:0011031) | 2.05589065 |
126 | Vomiting (HP:0002013) | 2.04028381 |
127 | Renal cortical cysts (HP:0000803) | 2.03820388 |
128 | Abnormality of cells of the erythroid lineage (HP:0012130) | 2.01953426 |
129 | Abnormality of DNA repair (HP:0003254) | 2.01161517 |
130 | Conical tooth (HP:0000698) | 2.00448961 |
131 | Aplasia/Hypoplasia of the spleen (HP:0010451) | 2.00161944 |
132 | Abnormal drinking behavior (HP:0030082) | 1.99428863 |
133 | Polydipsia (HP:0001959) | 1.99428863 |
134 | Hyperventilation (HP:0002883) | 1.98954989 |
135 | Pancreatitis (HP:0001733) | 1.98886841 |
136 | Esophageal neoplasm (HP:0100751) | 1.98705298 |
137 | Neoplasm of head and neck (HP:0012288) | 1.98705298 |
138 | Cardiovascular calcification (HP:0011915) | 1.98253739 |
139 | Furrowed tongue (HP:0000221) | 1.98114625 |
140 | Thrombophlebitis (HP:0004418) | 1.97629560 |
141 | Acute encephalopathy (HP:0006846) | 1.96958956 |
142 | Hepatocellular carcinoma (HP:0001402) | 1.96803198 |
143 | Bulbous nose (HP:0000414) | 1.96091312 |
144 | Exercise-induced myalgia (HP:0003738) | 1.95914532 |
145 | Abnormality of transition element cation homeostasis (HP:0011030) | 1.95703378 |
146 | Hepatocellular necrosis (HP:0001404) | 1.94750644 |
147 | Muscle hypertrophy of the lower extremities (HP:0008968) | 1.94549154 |
148 | Rhabdomyolysis (HP:0003201) | 1.94512402 |
149 | Ragged-red muscle fibers (HP:0003200) | 1.93653453 |
150 | Lactic acidosis (HP:0003128) | 1.92553998 |
151 | Menorrhagia (HP:0000132) | 1.92502186 |
152 | Lissencephaly (HP:0001339) | 1.91662842 |
153 | Decreased activity of mitochondrial respiratory chain (HP:0008972) | 1.91494571 |
154 | Abnormal activity of mitochondrial respiratory chain (HP:0011922) | 1.91494571 |
155 | Abnormality of alanine metabolism (HP:0010916) | 1.91189629 |
156 | Hyperalaninemia (HP:0003348) | 1.91189629 |
157 | Abnormality of pyruvate family amino acid metabolism (HP:0010915) | 1.91189629 |
158 | Myocardial infarction (HP:0001658) | 1.91103220 |
159 | Asplenia (HP:0001746) | 1.90582210 |
160 | Polyuria (HP:0000103) | 1.90548053 |
161 | Postaxial hand polydactyly (HP:0001162) | 1.89612950 |
162 | Aplasia/Hypoplasia of the optic nerve (HP:0008058) | 1.88174107 |
163 | Hypertriglyceridemia (HP:0002155) | 1.88152458 |
164 | Soft skin (HP:0000977) | 1.87809875 |
165 | Abnormality of complement system (HP:0005339) | 1.87200733 |
166 | Gingival bleeding (HP:0000225) | 1.86629618 |
167 | Palpitations (HP:0001962) | 1.85521336 |
168 | Mesangial abnormality (HP:0001966) | 1.84548569 |
169 | Congenital sensorineural hearing impairment (HP:0008527) | 1.84202610 |
170 | Methylmalonic acidemia (HP:0002912) | 1.84104130 |
171 | Abnormal gallbladder morphology (HP:0012437) | 1.83310012 |
172 | Optic nerve hypoplasia (HP:0000609) | 1.82151756 |
173 | Broad-based gait (HP:0002136) | 1.82099038 |
174 | Absent phalangeal crease (HP:0006109) | 1.81062125 |
175 | Pachygyria (HP:0001302) | 1.77948691 |
176 | Genital tract atresia (HP:0001827) | 1.75000642 |
177 | Round ear (HP:0100830) | 1.69956317 |
178 | Chronic hepatic failure (HP:0100626) | 1.69949378 |
179 | Bony spicule pigmentary retinopathy (HP:0007737) | 1.69816566 |
180 | Atrial fibrillation (HP:0005110) | 1.66267801 |
181 | Ulnar deviation of the wrist (HP:0003049) | 1.66150556 |
182 | Absent speech (HP:0001344) | 1.66108355 |
183 | Progressive microcephaly (HP:0000253) | 1.65717737 |
184 | Nonprogressive disorder (HP:0003680) | 1.65467015 |
185 | Rib fusion (HP:0000902) | 1.65014022 |
186 | Vaginal atresia (HP:0000148) | 1.64782574 |
187 | Prolonged QT interval (HP:0001657) | 1.64592385 |
188 | Concave nail (HP:0001598) | 1.62582674 |
189 | Inability to walk (HP:0002540) | 1.62487421 |
190 | Male pseudohermaphroditism (HP:0000037) | 1.62241821 |
191 | Bell-shaped thorax (HP:0001591) | 1.60098886 |
192 | Limited hip movement (HP:0008800) | 1.59682767 |
193 | Chorioretinal atrophy (HP:0000533) | 1.59242641 |
194 | Lipoatrophy (HP:0100578) | 1.59045848 |
195 | Abnormal glycosylation (HP:0012345) | 1.57827009 |
Rank | Gene Set | Z-score |
---|---|---|
1 | BCKDK | 7.19819078 |
2 | MAP4K2 | 4.50036426 |
3 | PKN2 | 4.36819751 |
4 | FRK | 4.08481021 |
5 | NME2 | 3.72181179 |
6 | ERN1 | 3.52473377 |
7 | SIK1 | 3.39159565 |
8 | TRIB3 | 2.94943612 |
9 | GRK1 | 2.71014480 |
10 | CCNB1 | 2.63960059 |
11 | ADRBK2 | 2.61890081 |
12 | FLT3 | 2.40203991 |
13 | NEK2 | 2.33613138 |
14 | BMPR1B | 2.31912172 |
15 | MAP2K3 | 2.29682704 |
16 | NUAK1 | 2.26740081 |
17 | LRRK2 | 2.20472713 |
18 | INSRR | 2.20422553 |
19 | WNK4 | 2.19439092 |
20 | FGFR4 | 2.07100681 |
21 | PTK2B | 1.93320898 |
22 | MAPK13 | 1.91904668 |
23 | ZAK | 1.88846868 |
24 | TGFBR2 | 1.84953030 |
25 | RPS6KB2 | 1.79564352 |
26 | TTN | 1.78453335 |
27 | VRK2 | 1.71405692 |
28 | TGFBR1 | 1.67571066 |
29 | PTK6 | 1.66213678 |
30 | CDK19 | 1.63562255 |
31 | TLK1 | 1.62813855 |
32 | MAP3K3 | 1.57554095 |
33 | PDK2 | 1.51427988 |
34 | TXK | 1.47616294 |
35 | TBK1 | 1.46537649 |
36 | MST1R | 1.36073170 |
37 | WNK3 | 1.32771701 |
38 | LIMK1 | 1.27538858 |
39 | STK39 | 1.25678626 |
40 | MUSK | 1.24118151 |
41 | TAF1 | 1.23986930 |
42 | PIK3CG | 1.19887599 |
43 | TIE1 | 1.18446907 |
44 | EEF2K | 1.17908078 |
45 | MAPKAPK5 | 1.10281969 |
46 | STK16 | 1.06793517 |
47 | TYK2 | 1.05917875 |
48 | NTRK1 | 1.04699168 |
49 | MARK1 | 1.03985388 |
50 | NEK9 | 1.01210788 |
51 | NTRK2 | 1.00328342 |
52 | PINK1 | 0.99073819 |
53 | TRIM28 | 0.98174237 |
54 | MAP2K6 | 0.96347383 |
55 | PDK4 | 0.95985361 |
56 | PDK3 | 0.95985361 |
57 | PRKCE | 0.95195302 |
58 | MET | 0.93718597 |
59 | CAMKK2 | 0.93116423 |
60 | MATK | 0.92854359 |
61 | MST4 | 0.92216202 |
62 | WEE1 | 0.91559753 |
63 | PLK2 | 0.90848500 |
64 | GRK5 | 0.90758017 |
65 | MAPK15 | 0.90570089 |
66 | DYRK1B | 0.89532977 |
67 | PRKCI | 0.83964029 |
68 | PRKD3 | 0.83547571 |
69 | BRSK2 | 0.83216288 |
70 | LMTK2 | 0.82424785 |
71 | JAK3 | 0.81808088 |
72 | MAP2K2 | 0.81464799 |
73 | PHKG2 | 0.81016962 |
74 | PHKG1 | 0.81016962 |
75 | MAP3K4 | 0.79317535 |
76 | RPS6KA4 | 0.79183000 |
77 | OBSCN | 0.77859120 |
78 | PKN1 | 0.76049241 |
79 | NEK1 | 0.73962391 |
80 | RIPK1 | 0.73511166 |
81 | HIPK2 | 0.73090735 |
82 | MAPK11 | 0.72796328 |
83 | PDGFRA | 0.72624970 |
84 | CSF1R | 0.72578291 |
85 | ROCK1 | 0.71956815 |
86 | FER | 0.71698413 |
87 | PRKD2 | 0.71097863 |
88 | PASK | 0.71030023 |
89 | MAPK12 | 0.69595719 |
90 | ACVR1B | 0.69455726 |
91 | TEC | 0.69418943 |
92 | BTK | 0.69170726 |
93 | NME1 | 0.68588701 |
94 | MAPKAPK3 | 0.67617830 |
95 | MAP3K7 | 0.67228833 |
96 | MYLK | 0.65634098 |
97 | KDR | 0.62593670 |
98 | DAPK2 | 0.62090909 |
99 | KIT | 0.62013800 |
100 | IKBKB | 0.61584014 |
101 | CDK6 | 0.61501501 |
102 | EPHB2 | 0.61440098 |
103 | VRK1 | 0.58275429 |
104 | IRAK3 | 0.58107850 |
105 | LATS1 | 0.57764427 |
106 | STK38 | 0.57039107 |
107 | EPHA2 | 0.55506680 |
108 | STK3 | 0.55465681 |
109 | CHUK | 0.55112054 |
110 | JAK2 | 0.54593635 |
111 | PRKCQ | 0.52812924 |
112 | STK38L | 0.52407134 |
113 | OXSR1 | 0.51511725 |
114 | MAP2K1 | 0.51059152 |
115 | CDK4 | 0.50891142 |
116 | DDR2 | 0.50881697 |
117 | ZAP70 | 0.49631870 |
118 | PRKG2 | 0.49389688 |
119 | RET | 0.48335602 |
120 | ARAF | 0.47856769 |
121 | PAK3 | 0.47542668 |
122 | ABL2 | 0.46500727 |
123 | CAMK2D | 0.46218428 |
124 | PRKAA2 | 0.45687466 |
125 | PIK3CA | 0.45027126 |
126 | CAMK1 | 0.44989787 |
127 | PAK2 | 0.44619475 |
128 | NTRK3 | 0.44510207 |
129 | PRKACA | 0.44438175 |
130 | EPHA3 | 0.44432628 |
131 | ERBB4 | 0.44381947 |
132 | IKBKE | 0.43787938 |
133 | GRK7 | 0.42212093 |
134 | EIF2AK3 | 0.41345640 |
135 | PRKCG | 0.41315174 |
136 | CAMK2A | 0.41158159 |
137 | FGFR1 | 0.40822277 |
138 | AKT2 | 0.40746536 |
139 | TAOK3 | 0.40479874 |
140 | PRKD1 | 0.39123405 |
141 | PIM2 | 0.39070452 |
142 | DYRK2 | 0.38449223 |
143 | MTOR | 0.38080572 |
144 | STK10 | 0.38029190 |
145 | CDK8 | 0.37847076 |
146 | DAPK3 | 0.35373756 |
147 | CSNK1G3 | 0.34227763 |
148 | DYRK3 | 0.33816032 |
149 | CSNK1G2 | 0.33631007 |
150 | PRKCA | 0.32559728 |
151 | EIF2AK2 | 0.31575370 |
152 | TRPM7 | 0.31393451 |
153 | CSNK1G1 | 0.31185231 |
154 | PTK2 | 0.29788045 |
155 | PRKAA1 | 0.29328312 |
156 | PRKG1 | 0.28586313 |
157 | STK4 | 0.28239604 |
158 | ILK | 0.27551547 |
159 | TAOK2 | 0.26943570 |
160 | ERBB2 | 0.26935146 |
161 | EPHB1 | 0.25953486 |
162 | PIM1 | 0.25644223 |
163 | ADRBK1 | 0.25379217 |
164 | IRAK1 | 0.23878456 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Primary bile acid biosynthesis_Homo sapiens_hsa00120 | 3.39189254 |
2 | Ascorbate and aldarate metabolism_Homo sapiens_hsa00053 | 3.26560868 |
3 | Fatty acid degradation_Homo sapiens_hsa00071 | 2.82488981 |
4 | Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa00563 | 2.81091529 |
5 | Pentose and glucuronate interconversions_Homo sapiens_hsa00040 | 2.76662857 |
6 | Valine, leucine and isoleucine degradation_Homo sapiens_hsa00280 | 2.73407098 |
7 | Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa00630 | 2.66273591 |
8 | Propanoate metabolism_Homo sapiens_hsa00640 | 2.50349004 |
9 | Glycine, serine and threonine metabolism_Homo sapiens_hsa00260 | 2.41456336 |
10 | Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa00400 | 2.39344185 |
11 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 2.33207931 |
12 | Nitrogen metabolism_Homo sapiens_hsa00910 | 2.33092394 |
13 | Phototransduction_Homo sapiens_hsa04744 | 2.32289194 |
14 | Sulfur relay system_Homo sapiens_hsa04122 | 2.31101889 |
15 | Peroxisome_Homo sapiens_hsa04146 | 2.27340673 |
16 | Tryptophan metabolism_Homo sapiens_hsa00380 | 2.24018113 |
17 | Arginine biosynthesis_Homo sapiens_hsa00220 | 2.14310049 |
18 | Caffeine metabolism_Homo sapiens_hsa00232 | 2.11296045 |
19 | Cardiac muscle contraction_Homo sapiens_hsa04260 | 2.10238421 |
20 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 2.04545986 |
21 | Complement and coagulation cascades_Homo sapiens_hsa04610 | 1.94256564 |
22 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 1.93083713 |
23 | Drug metabolism - cytochrome P450_Homo sapiens_hsa00982 | 1.91998400 |
24 | Chemical carcinogenesis_Homo sapiens_hsa05204 | 1.90441919 |
25 | Butanoate metabolism_Homo sapiens_hsa00650 | 1.89030320 |
26 | Fatty acid metabolism_Homo sapiens_hsa01212 | 1.87820395 |
27 | Neuroactive ligand-receptor interaction_Homo sapiens_hsa04080 | 1.86363651 |
28 | beta-Alanine metabolism_Homo sapiens_hsa00410 | 1.81749098 |
29 | Metabolism of xenobiotics by cytochrome P450_Homo sapiens_hsa00980 | 1.77288030 |
30 | Drug metabolism - other enzymes_Homo sapiens_hsa00983 | 1.75992502 |
31 | Folate biosynthesis_Homo sapiens_hsa00790 | 1.75750266 |
32 | Sulfur metabolism_Homo sapiens_hsa00920 | 1.75414362 |
33 | Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa00603 | 1.75347735 |
34 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.72682375 |
35 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 1.59611682 |
36 | PPAR signaling pathway_Homo sapiens_hsa03320 | 1.57446948 |
37 | Carbon metabolism_Homo sapiens_hsa01200 | 1.56430978 |
38 | Selenocompound metabolism_Homo sapiens_hsa00450 | 1.49973777 |
39 | Maturity onset diabetes of the young_Homo sapiens_hsa04950 | 1.48741064 |
40 | Basal transcription factors_Homo sapiens_hsa03022 | 1.47856718 |
41 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.47730530 |
42 | Cysteine and methionine metabolism_Homo sapiens_hsa00270 | 1.47593151 |
43 | Olfactory transduction_Homo sapiens_hsa04740 | 1.44652726 |
44 | Porphyrin and chlorophyll metabolism_Homo sapiens_hsa00860 | 1.44163920 |
45 | Pyruvate metabolism_Homo sapiens_hsa00620 | 1.42449547 |
46 | Fatty acid elongation_Homo sapiens_hsa00062 | 1.42368680 |
47 | Histidine metabolism_Homo sapiens_hsa00340 | 1.42113434 |
48 | Ribosome_Homo sapiens_hsa03010 | 1.42093877 |
49 | Pantothenate and CoA biosynthesis_Homo sapiens_hsa00770 | 1.41950784 |
50 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.41015922 |
51 | Steroid hormone biosynthesis_Homo sapiens_hsa00140 | 1.40888391 |
52 | Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa00130 | 1.38643035 |
53 | Retinol metabolism_Homo sapiens_hsa00830 | 1.36144600 |
54 | Synthesis and degradation of ketone bodies_Homo sapiens_hsa00072 | 1.33978274 |
55 | Starch and sucrose metabolism_Homo sapiens_hsa00500 | 1.31499631 |
56 | Huntingtons disease_Homo sapiens_hsa05016 | 1.27583766 |
57 | Phenylalanine metabolism_Homo sapiens_hsa00360 | 1.27361385 |
58 | Cyanoamino acid metabolism_Homo sapiens_hsa00460 | 1.24801361 |
59 | Ether lipid metabolism_Homo sapiens_hsa00565 | 1.23491462 |
60 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 1.22252845 |
61 | Calcium signaling pathway_Homo sapiens_hsa04020 | 1.18341428 |
62 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.17343233 |
63 | Nicotine addiction_Homo sapiens_hsa05033 | 1.12565812 |
64 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 1.11435131 |
65 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.10051619 |
66 | Salivary secretion_Homo sapiens_hsa04970 | 1.08079576 |
67 | Regulation of autophagy_Homo sapiens_hsa04140 | 1.05407672 |
68 | Tyrosine metabolism_Homo sapiens_hsa00350 | 1.04490610 |
69 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 1.04390111 |
70 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.03828005 |
71 | Taste transduction_Homo sapiens_hsa04742 | 1.03541867 |
72 | Circadian rhythm_Homo sapiens_hsa04710 | 1.03016390 |
73 | Fat digestion and absorption_Homo sapiens_hsa04975 | 1.01797381 |
74 | Intestinal immune network for IgA production_Homo sapiens_hsa04672 | 1.01312642 |
75 | Homologous recombination_Homo sapiens_hsa03440 | 1.01128674 |
76 | Nicotinate and nicotinamide metabolism_Homo sapiens_hsa00760 | 0.99672446 |
77 | Insulin secretion_Homo sapiens_hsa04911 | 0.97703419 |
78 | Staphylococcus aureus infection_Homo sapiens_hsa05150 | 0.97399222 |
79 | One carbon pool by folate_Homo sapiens_hsa00670 | 0.93356882 |
80 | Fanconi anemia pathway_Homo sapiens_hsa03460 | 0.91069710 |
81 | Glutathione metabolism_Homo sapiens_hsa00480 | 0.90661775 |
82 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.90025950 |
83 | ABC transporters_Homo sapiens_hsa02010 | 0.84086172 |
84 | Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 0.83936072 |
85 | Galactose metabolism_Homo sapiens_hsa00052 | 0.82050120 |
86 | Morphine addiction_Homo sapiens_hsa05032 | 0.81377172 |
87 | ECM-receptor interaction_Homo sapiens_hsa04512 | 0.81196603 |
88 | Taurine and hypotaurine metabolism_Homo sapiens_hsa00430 | 0.80288434 |
89 | Ovarian steroidogenesis_Homo sapiens_hsa04913 | 0.78962057 |
90 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 0.77200603 |
91 | RNA polymerase_Homo sapiens_hsa03020 | 0.71501396 |
92 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.70179543 |
93 | Bile secretion_Homo sapiens_hsa04976 | 0.69074565 |
94 | Vitamin digestion and absorption_Homo sapiens_hsa04977 | 0.68573520 |
95 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.68430452 |
96 | Lysine degradation_Homo sapiens_hsa00310 | 0.63935560 |
97 | Glycerolipid metabolism_Homo sapiens_hsa00561 | 0.62091178 |
98 | Metabolic pathways_Homo sapiens_hsa01100 | 0.61174599 |
99 | Glutamatergic synapse_Homo sapiens_hsa04724 | 0.59266696 |
100 | Circadian entrainment_Homo sapiens_hsa04713 | 0.58005933 |
101 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.57836472 |
102 | Fatty acid biosynthesis_Homo sapiens_hsa00061 | 0.57635618 |
103 | GABAergic synapse_Homo sapiens_hsa04727 | 0.56264542 |
104 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.55825309 |
105 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.53996583 |
106 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.52958280 |
107 | Renin secretion_Homo sapiens_hsa04924 | 0.51624201 |
108 | Adipocytokine signaling pathway_Homo sapiens_hsa04920 | 0.49640396 |
109 | Serotonergic synapse_Homo sapiens_hsa04726 | 0.49356324 |
110 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.48632184 |
111 | Nucleotide excision repair_Homo sapiens_hsa03420 | 0.48133200 |
112 | * Cytokine-cytokine receptor interaction_Homo sapiens_hsa04060 | 0.47571560 |
113 | Glycosaminoglycan biosynthesis - keratan sulfate_Homo sapiens_hsa00533 | 0.46109013 |
114 | Base excision repair_Homo sapiens_hsa03410 | 0.46026528 |
115 | cAMP signaling pathway_Homo sapiens_hsa04024 | 0.45999990 |
116 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 0.45386276 |
117 | Non-alcoholic fatty liver disease (NAFLD)_Homo sapiens_hsa04932 | 0.44947236 |
118 | Insulin resistance_Homo sapiens_hsa04931 | 0.40887203 |
119 | alpha-Linolenic acid metabolism_Homo sapiens_hsa00592 | 0.34545172 |
120 | Glycosphingolipid biosynthesis - lacto and neolacto series_Homo sapiens_hsa00601 | 0.29319616 |
121 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.29138787 |
122 | Linoleic acid metabolism_Homo sapiens_hsa00591 | 0.25288243 |
123 | Pyrimidine metabolism_Homo sapiens_hsa00240 | 0.23908066 |
124 | Cytosolic DNA-sensing pathway_Homo sapiens_hsa04623 | 0.21998652 |
125 | Arachidonic acid metabolism_Homo sapiens_hsa00590 | 0.19372868 |
126 | Steroid biosynthesis_Homo sapiens_hsa00100 | 0.19134134 |
127 | Parkinsons disease_Homo sapiens_hsa05012 | 0.14724263 |
128 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.12852237 |
129 | Prion diseases_Homo sapiens_hsa05020 | 0.12323124 |
130 | Legionellosis_Homo sapiens_hsa05134 | 0.11610350 |
131 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.11333561 |
132 | Bladder cancer_Homo sapiens_hsa05219 | 0.10913026 |
133 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 0.10621884 |
134 | Protein digestion and absorption_Homo sapiens_hsa04974 | 0.09854052 |
135 | Protein export_Homo sapiens_hsa03060 | 0.09765734 |
136 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 0.09705051 |
137 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.05405858 |
138 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 0.04491375 |
139 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.04247514 |
140 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 0.02229471 |
141 | RIG-I-like receptor signaling pathway_Homo sapiens_hsa04622 | 0.00936084 |
142 | Oxidative phosphorylation_Homo sapiens_hsa00190 | 0.00321323 |
143 | Alzheimers disease_Homo sapiens_hsa05010 | -0.0250437 |
144 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | -0.0168542 |
145 | Notch signaling pathway_Homo sapiens_hsa04330 | -0.0075246 |