CTNNAL1

Predicted funtional terms: GO | ChEA | Mouse Phenotype | Human Phenotype | KEA | KEGG
Most similar genes based on co-expression: Pearson correlation
Expression levels across tissues and cell lines: Tissue Expression | Cell Line Expression





Description: No gene information available for this gene. NCBI Entrez Gene | GeneCards | Harmonizome

Functional Annotation Prediction

Predicted biological processes (GO)

RankGene SetZ-score
1DNA unwinding involved in DNA replication (GO:0006268)4.77201745
2regulation of posttranscriptional gene silencing (GO:0060147)4.43488633
3regulation of gene silencing by miRNA (GO:0060964)4.43488633
4regulation of gene silencing by RNA (GO:0060966)4.43488633
5establishment of integrated proviral latency (GO:0075713)4.24594971
6regulation of attachment of spindle microtubules to kinetochore (GO:0051988)4.23259878
7paraxial mesoderm development (GO:0048339)4.15476717
8DNA strand elongation involved in DNA replication (GO:0006271)3.93694866
9DNA strand elongation (GO:0022616)3.81161948
10mitotic metaphase plate congression (GO:0007080)3.75851527
11telomere maintenance via semi-conservative replication (GO:0032201)3.66228439
12positive regulation of chromosome segregation (GO:0051984)3.62877038
13nuclear pore organization (GO:0006999)3.50089331
14nucleobase-containing small molecule interconversion (GO:0015949)3.49528140
15regulation of meiosis I (GO:0060631)3.43113408
16notochord development (GO:0030903)3.42723382
17mitotic sister chromatid cohesion (GO:0007064)3.38709418
18hemidesmosome assembly (GO:0031581)3.34905624
19cell-cell junction maintenance (GO:0045217)3.33774686
20intestinal epithelial cell development (GO:0060576)3.27239174
21regulation of sister chromatid cohesion (GO:0007063)3.25849597
22COPI coating of Golgi vesicle (GO:0048205)3.24843424
23Golgi transport vesicle coating (GO:0048200)3.24843424
24peripheral nervous system axon ensheathment (GO:0032292)3.23546742
25myelination in peripheral nervous system (GO:0022011)3.23546742
26DNA replication-dependent nucleosome organization (GO:0034723)3.23439169
27DNA replication-dependent nucleosome assembly (GO:0006335)3.23439169
28regulation of hippo signaling (GO:0035330)3.19871292
29ventricular cardiac muscle cell development (GO:0055015)3.19262719
30nuclear pore complex assembly (GO:0051292)3.17822616
31mitotic recombination (GO:0006312)3.16143182
32telomere maintenance via recombination (GO:0000722)3.15967147
33protein maturation by protein folding (GO:0022417)3.15574758
34establishment of viral latency (GO:0019043)3.14488762
35metaphase plate congression (GO:0051310)3.14274754
36regulation of helicase activity (GO:0051095)3.10899909
37positive regulation of catenin import into nucleus (GO:0035413)3.10745121
38positive regulation of neurological system process (GO:0031646)3.10189898
39heterochromatin organization (GO:0070828)3.10036609
40DNA replication checkpoint (GO:0000076)3.06649367
41chromosome condensation (GO:0030261)3.05669188
42anterior/posterior axis specification, embryo (GO:0008595)3.01950665
43histone H2A monoubiquitination (GO:0035518)3.00480999
44ribosome assembly (GO:0042255)2.98005204
45regulation of spindle organization (GO:0090224)2.97450606
46protein localization to kinetochore (GO:0034501)2.95824226
47mitotic cytokinesis (GO:0000281)2.95628055
48regulation of translational fidelity (GO:0006450)2.95092018
49axon ensheathment (GO:0008366)2.94483283
50ensheathment of neurons (GO:0007272)2.94483283
51kinetochore organization (GO:0051383)2.94128641
52protein K6-linked ubiquitination (GO:0085020)2.93317769
53lung-associated mesenchyme development (GO:0060484)2.93171851
54cellular protein complex localization (GO:0034629)2.92856123
55regulation of centriole replication (GO:0046599)2.89731458
56mitotic chromosome condensation (GO:0007076)2.89348008
57cell junction maintenance (GO:0034331)2.89232985
58regulation of exit from mitosis (GO:0007096)2.87285351
59hippo signaling (GO:0035329)2.85583082
60formation of translation preinitiation complex (GO:0001731)2.81709284
61regulation of chromosome segregation (GO:0051983)2.80603332
62proteasome assembly (GO:0043248)2.79150496
63response to hepatocyte growth factor (GO:0035728)2.77317710
64cellular response to hepatocyte growth factor stimulus (GO:0035729)2.77317710
65spindle assembly involved in mitosis (GO:0090307)2.77082545
66regulation of mitotic spindle organization (GO:0060236)2.76746679
67DNA packaging (GO:0006323)2.74029767
68mitotic nuclear envelope disassembly (GO:0007077)2.72398078
69male sex determination (GO:0030238)2.71848947
70negative regulation of meiosis (GO:0045835)2.71567640
71myelination (GO:0042552)2.70499632
72non-recombinational repair (GO:0000726)2.69981130
73double-strand break repair via nonhomologous end joining (GO:0006303)2.69981130
74deoxyribonucleotide biosynthetic process (GO:0009263)2.68788101
75regulation of cardioblast differentiation (GO:0051890)2.67433128
76DNA damage induced protein phosphorylation (GO:0006975)2.66723006
77negative regulation of retinoic acid receptor signaling pathway (GO:0048387)2.66393088
78maturation of 5.8S rRNA (GO:0000460)2.66359746
79cell adhesion mediated by integrin (GO:0033627)2.65511771
80regulation of translational termination (GO:0006449)2.65147599
81positive regulation of SMAD protein import into nucleus (GO:0060391)2.64930419
82spindle checkpoint (GO:0031577)2.64829201
83regulation of transcription involved in G1/S transition of mitotic cell cycle (GO:0000083)2.64480548
84microtubule cytoskeleton organization involved in mitosis (GO:1902850)2.63474348
85mitotic sister chromatid segregation (GO:0000070)2.63345162
86negative regulation of histone methylation (GO:0031061)2.63172633
87attachment of spindle microtubules to kinetochore (GO:0008608)2.62912561
88chromatin remodeling at centromere (GO:0031055)2.61507671
89DNA topological change (GO:0006265)2.61060404
90establishment of apical/basal cell polarity (GO:0035089)2.60360718
91regulation of transforming growth factor beta2 production (GO:0032909)2.60155650
92chromosome segregation (GO:0007059)2.58589776
93DNA duplex unwinding (GO:0032508)2.58320219
94membrane disassembly (GO:0030397)2.56767527
95nuclear envelope disassembly (GO:0051081)2.56767527
96polarized epithelial cell differentiation (GO:0030859)2.56126263
97mitotic spindle checkpoint (GO:0071174)2.55797261
98nucleotide-excision repair, DNA gap filling (GO:0006297)2.54293361
99regulation of telomere maintenance via telomerase (GO:0032210)2.53421012
100maintenance of protein localization in endoplasmic reticulum (GO:0035437)2.52968968
101negative regulation of DNA repair (GO:0045738)2.51715743
102positive regulation of DNA-dependent DNA replication (GO:2000105)2.50884895
103negative regulation of chromosome segregation (GO:0051985)2.50249683
104establishment of chromosome localization (GO:0051303)2.50123893
105CENP-A containing nucleosome assembly (GO:0034080)2.48339930
106protein complex localization (GO:0031503)2.48005441
107female gonad development (GO:0008585)2.47608285
108IMP biosynthetic process (GO:0006188)2.47249027
109DNA conformation change (GO:0071103)2.46840200
110DNA geometric change (GO:0032392)2.46833821
111DNA replication initiation (GO:0006270)2.46358453
112positive regulation of mitotic sister chromatid separation (GO:1901970)2.46030073
113positive regulation of mitotic metaphase/anaphase transition (GO:0045842)2.46030073
114positive regulation of metaphase/anaphase transition of cell cycle (GO:1902101)2.46030073
115anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process (GO:02.45891882
116purine nucleobase biosynthetic process (GO:0009113)2.45557275
117negative regulation of mitotic sister chromatid separation (GO:2000816)2.45189677
118negative regulation of mitotic sister chromatid segregation (GO:0033048)2.45189677
119negative regulation of mitotic metaphase/anaphase transition (GO:0045841)2.45189677
120negative regulation of sister chromatid segregation (GO:0033046)2.45189677
121regulation of gene silencing (GO:0060968)2.44924397
122blastocyst development (GO:0001824)2.44814502
123cytoskeleton-dependent cytokinesis (GO:0061640)2.44315353
124negative regulation of metaphase/anaphase transition of cell cycle (GO:1902100)2.43291649
125mitotic spindle organization (GO:0007052)2.42646189
126glomerular basement membrane development (GO:0032836)2.41494130
127protein localization to chromosome, centromeric region (GO:0071459)2.41354786
128sister chromatid segregation (GO:0000819)2.40732294
129ribosomal large subunit biogenesis (GO:0042273)2.40601269
130histone exchange (GO:0043486)2.40467798
131telomere maintenance via telomere lengthening (GO:0010833)2.39981468
132Leydig cell differentiation (GO:0033327)2.39707217
133pore complex assembly (GO:0046931)2.38897371
134endothelial cell morphogenesis (GO:0001886)2.38743243
135mitotic spindle assembly checkpoint (GO:0007094)2.37957177
136myelin assembly (GO:0032288)2.37678069
137regulation of transcription from RNA polymerase I promoter (GO:0006356)2.37110359
138regulation of mitotic metaphase/anaphase transition (GO:0030071)2.36532351
139somatic hypermutation of immunoglobulin genes (GO:0016446)2.36156457
140somatic diversification of immune receptors via somatic mutation (GO:0002566)2.36156457
141spindle assembly checkpoint (GO:0071173)2.35941945
142regulation of metaphase/anaphase transition of cell cycle (GO:1902099)2.35262451
143regulation of mitotic sister chromatid separation (GO:0010965)2.34746204
144regulation of mitotic sister chromatid segregation (GO:0033047)2.34746204
145regulation of sister chromatid segregation (GO:0033045)2.34746204
146DNA replication-independent nucleosome assembly (GO:0006336)2.34393930
147DNA replication-independent nucleosome organization (GO:0034724)2.34393930
148regulation of centrosome cycle (GO:0046605)2.34175969
149regulation of histone H3-K9 methylation (GO:0051570)2.33943912
150chromatin assembly or disassembly (GO:0006333)2.33538563
151mitotic cell cycle (GO:0000278)2.32751880
152IMP metabolic process (GO:0046040)2.32743225
153cell cycle G1/S phase transition (GO:0044843)2.32299313
154G1/S transition of mitotic cell cycle (GO:0000082)2.32299313
155meiotic chromosome segregation (GO:0045132)2.31897938

Predicted upstream transcription factors (ChEA)

RankGene SetZ-score
1E2F7_22180533_ChIP-Seq_HELA_Human5.62540486
2SALL1_21062744_ChIP-ChIP_HESCs_Human4.01967478
3KLF2_18264089_ChIP-ChIP_MESCs_Mouse3.78617726
4KLF5_18264089_ChIP-ChIP_MESCs_Mouse3.78617726
5KLF4_18264089_ChIP-ChIP_MESCs_Mouse3.78617726
6FOXM1_23109430_ChIP-Seq_U2OS_Human3.29060915
7EKLF_21900194_ChIP-Seq_ERYTHROCYTE_Mouse3.28802421
8NANOG_18700969_ChIP-ChIP_MESCs_Mouse2.91327723
9POU5F1_18700969_ChIP-ChIP_MESCs_Mouse2.76666327
10AR_21909140_ChIP-Seq_LNCAP_Human2.76285576
11* KDM5B_21448134_ChIP-Seq_MESCs_Mouse2.73931092
12E2F4_17652178_ChIP-ChIP_JURKAT_Human2.43251950
13HCFC1_20581084_ChIP-Seq_MESCs_Mouse2.39393523
14ZIC3_20872845_ChIP-ChIP_MESCs_Mouse2.38449118
15FOXM1_25889361_ChIP-Seq_OE33_AND_U2OS_Human2.37190013
16SMAD1_18555785_ChIP-Seq_MESCs_Mouse2.36846437
17MYC_18555785_ChIP-Seq_MESCs_Mouse2.35971901
18SALL4_18804426_ChIP-ChIP_MESCs_Mouse2.34983542
19TCF3_18692474_ChIP-Seq_MEFs_Mouse2.29236037
20SMAD3_22036565_ChIP-Seq_ESCs_Mouse2.26434040
21TCF3_18692474_ChIP-Seq_MESCs_Mouse2.21016524
22HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse2.17125492
23MYC_19079543_ChIP-ChIP_MESCs_Mouse2.15356443
24NACC1_18358816_ChIP-ChIP_MESCs_Mouse2.15012170
25SOX2_18358816_ChIP-ChIP_MESCs_Mouse2.14061623
26NANOG_18555785_ChIP-Seq_MESCs_Mouse2.09782126
27SOX2_18555785_ChIP-Seq_MESCs_Mouse2.00962968
28TP63_17297297_ChIP-ChIP_HaCaT_Human1.97219080
29DCP1A_22483619_ChIP-Seq_HELA_Human1.93137321
30MYBL2_22936984_ChIP-ChIP_MESCs_Mouse1.91588576
31CHD1_19587682_ChIP-ChIP_MESCs_Mouse1.89298172
32NANOG_18347094_ChIP-ChIP_MESCs_Mouse1.83698338
33CLOCK_20551151_ChIP-Seq_293T_Human1.82756735
34E4F1_26484288_ChIP-Seq_MOUSE_EMBRYONIC_FIBROBLAST_Mouse1.78299964
35ZNF263_19887448_ChIP-Seq_K562_Human1.75037047
36NELFA_20434984_ChIP-Seq_ESCs_Mouse1.74306144
37THAP11_20581084_ChIP-Seq_MESCs_Mouse1.71357770
38MYBL1_21750041_ChIP-ChIP_SPERMATOCYTES_Mouse1.69932207
39MYC_19030024_ChIP-ChIP_MESCs_Mouse1.69550035
40NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse1.69488080
41JARID1A_20064375_ChIP-Seq_MESCs_Mouse1.65170468
42POU5F1_18358816_ChIP-ChIP_MESCs_Mouse1.61732930
43TCF3_18347094_ChIP-ChIP_MESCs_Mouse1.54832621
44DACH1_20351289_ChIP-Seq_MDA-MB-231_Human1.53710551
45POU5F1_16153702_ChIP-ChIP_HESCs_Human1.51125259
46TTF2_22483619_ChIP-Seq_HELA_Human1.49283405
47* NANOG_18692474_ChIP-Seq_MESCs_Mouse1.47945908
48TP63_19390658_ChIP-ChIP_HaCaT_Human1.46789845
49* NANOG_18692474_ChIP-Seq_MEFs_Mouse1.45997920
50NANOG_18358816_ChIP-ChIP_MESCs_Mouse1.44377059
51HOXA2_22223247_ChIP-Seq_E11.5_EMBRYO_Mouse1.43501534
52CREB1_15753290_ChIP-ChIP_HEK293T_Human1.43011406
53MYCN_18555785_ChIP-Seq_MESCs_Mouse1.42228217
54* SOX2_18692474_ChIP-Seq_MESCs_Mouse1.41611779
55POU5F1_16518401_ChIP-PET_MESCs_Mouse1.41119538
56* EOMES_20176728_ChIP-ChIP_TSCs_Mouse1.37771787
57POU5F1_18347094_ChIP-ChIP_MESCs_Mouse1.36480773
58SOX2_19030024_ChIP-ChIP_MESCs_Mouse1.35953987
59* STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse1.35484458
60ESR1_21235772_ChIP-Seq_MCF-7_Human1.34567662
61* SOX2_18692474_ChIP-Seq_MEFs_Mouse1.34477575
62KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human1.34292142
63POU5F1_18555785_ChIP-Seq_MESCs_Mouse1.34051024
64ZFP281_18358816_ChIP-ChIP_MESCs_Mouse1.33420772
65RBPJ_22232070_ChIP-Seq_NCS_Mouse1.33292400
66FOXO3_22982991_ChIP-Seq_MACROPHAGES_Mouse1.32766755
67HSF1_23293686_ChIP-Seq_STHDH_STRIATAL_Mouse1.32562076
68NANOG_21062744_ChIP-ChIP_HESCs_Human1.32425425
69E2F1_21310950_ChIP-Seq_MCF-7_Human1.30848475
70TAF7L_23326641_ChIP-Seq_C3H10T1-2_Mouse1.30190528
71PRDM14_21183938_ChIP-Seq_MESCs_Mouse1.27740262
72NKX2-5_21415370_ChIP-Seq_HL-1_Mouse1.27172533
73* CREM_20920259_ChIP-Seq_GC1-SPG_Mouse1.26785358
74KDM6A_18722178_ChIP-ChIP_U937_AND_SAOS2_Human1.26641565
75HIF1A_21447827_ChIP-Seq_MCF-7_Human1.26313657
76RARG_19884340_ChIP-ChIP_MEFs_Mouse1.24793697
77SALL4_18804426_ChIP-ChIP_XEN_Mouse1.23180294
78* SMAD3_18955504_ChIP-ChIP_HaCaT_Human1.23153321
79* SMAD2_18955504_ChIP-ChIP_HaCaT_Human1.23153321
80TRIM28_21343339_ChIP-Seq_HEK293_Human1.23094644
81TBX3_20139965_ChIP-Seq_MESCs_Mouse1.22263832
82GABP_19822575_ChIP-Seq_HepG2_Human1.21865240
83TBX3_20139965_ChIP-Seq_ESCs_Mouse1.21536134
84STAT3_1855785_ChIP-Seq_MESCs_Mouse1.20933365
85* E2F1_18555785_ChIP-Seq_MESCs_Mouse1.20777948
86WT1_19549856_ChIP-ChIP_CCG9911_Human1.20645925
87TCF3_18467660_ChIP-ChIP_MESCs_Mouse1.18560681
88PADI4_21655091_ChIP-ChIP_MCF-7_Human1.18446073
89CCND1_20090754_ChIP-ChIP_RETINA_Mouse1.17924433
90SOX2_16153702_ChIP-ChIP_HESCs_Human1.16644233
91PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse1.16206939
92NANOG_16153702_ChIP-ChIP_HESCs_Human1.15544008
93* CNOT3_19339689_ChIP-ChIP_MESCs_Mouse1.14430724
94TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse1.13260356
95ESR2_21235772_ChIP-Seq_MCF-7_Human1.11932179
96SMAD4_19686287_ChIP-ChIP_HaCaT_Human1.10837273
97BRD4_25478319_ChIP-Seq_HGPS_Human1.10053933
98ASH2L_23239880_ChIP-Seq_MESCs_Mouse1.09982135
99STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse1.09910819
100* KLF4_18555785_ChIP-Seq_MESCs_Mouse1.09537933
101PRDM5_23873026_ChIP-Seq_MEFs_Mouse1.09398847
102SOX17_20123909_ChIP-Seq_XEN_Mouse1.09176818
103SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse1.08887006
104ZFP42_18358816_ChIP-ChIP_MESCs_Mouse1.07630959
105GATA4_21415370_ChIP-Seq_HL-1_Mouse1.07319562
106* TRIM28_19339689_ChIP-ChIP_MESCs_Mouse1.07178846
107* ATF3_27146783_Chip-Seq_COLON_Human1.07163782
108YY1_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse1.06338043
109* KLF4_19030024_ChIP-ChIP_MESCs_Mouse1.05714369
110E2F4_21247883_ChIP-Seq_LYMPHOBLASTOID_Human1.05337019
111EST1_17652178_ChIP-ChIP_JURKAT_Human1.05317956
112TFEB_21752829_ChIP-Seq_HELA_Human1.05240441
113CREB1_23762244_ChIP-Seq_HIPPOCAMPUS_Rat1.05151130
114RUNX2_24764292_ChIP-Seq_MC3T3_Mouse1.02248790
115ETS1_20019798_ChIP-Seq_JURKAT_Human1.01343596
116HOXB4_20404135_ChIP-ChIP_EML_Mouse1.01193939
117MYC_18358816_ChIP-ChIP_MESCs_Mouse0.99093768
118FUS_26573619_Chip-Seq_HEK293_Human0.98910417
119FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse0.98338907
120CREB1_20920259_ChIP-Seq_GC1-SPG_Mouse0.97504311
121TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse0.96710239
122GABP_17652178_ChIP-ChIP_JURKAT_Human0.96186434
123NANOG_16518401_ChIP-PET_MESCs_Mouse0.96172435
124FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human0.95787469
125KAP1_27257070_Chip-Seq_ESCs_Mouse0.94831762
126* FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human0.94713699
127ERG_20887958_ChIP-Seq_HPC-7_Mouse0.93921765
128KLF4_18358816_ChIP-ChIP_MESCs_Mouse0.93488621
129ATF3_23680149_ChIP-Seq_GBM1-GSC_Human0.92668144
130SREBP1_19666523_ChIP-Seq_LIVER_Mouse0.92419260
131* ZFX_18555785_ChIP-Seq_MESCs_Mouse0.91758334
132MEF2A_21415370_ChIP-Seq_HL-1_Mouse0.91505586
133POU5F1_18692474_ChIP-Seq_MESCs_Mouse0.91313221
134TBX5_21415370_ChIP-Seq_HL-1_Mouse0.90267397
135KDM5A_27292631_Chip-Seq_BREAST_Human0.89310410
136HNF4A_19761587_ChIP-ChIP_CACO-2_Human0.89265232
137XRN2_22483619_ChIP-Seq_HELA_Human0.84806095
138CHD1_26751641_Chip-Seq_LNCaP_Human0.84595256
139EGR1_19374776_ChIP-ChIP_THP-1_Human0.84354244
140PPARG_23326641_ChIP-Seq_C3H10T1-2_Mouse0.84064307
141ELK1_19687146_ChIP-ChIP_HELA_Human0.82952553
142TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat0.82677551
143DMRT1_21621532_ChIP-ChIP_FETAL_Ovary0.80444541
144* TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse0.78672440

Predicted mouse phenotypes (MGI)

RankGene SetZ-score
1MP0003136_yellow_coat_color2.85792771
2MP0003705_abnormal_hypodermis_morpholog2.82087680
3MP0004272_abnormal_basement_membrane2.60887894
4MP0004957_abnormal_blastocyst_morpholog2.35098942
5MP0003693_abnormal_embryo_hatching2.31775549
6MP0008057_abnormal_DNA_replication2.22359470
7MP0009697_abnormal_copulation2.21599280
8MP0002653_abnormal_ependyma_morphology2.17686399
9MP0003111_abnormal_nucleus_morphology2.13601090
10MP0005257_abnormal_intraocular_pressure2.05490222
11MP0003937_abnormal_limbs/digits/tail_de2.03422044
12MP0005623_abnormal_meninges_morphology2.03146455
13MP0010368_abnormal_lymphatic_system1.95199377
14MP0010030_abnormal_orbit_morphology1.93648157
15MP0003315_abnormal_perineum_morphology1.90301245
16MP0003123_paternal_imprinting1.90075250
17MP0003077_abnormal_cell_cycle1.86859665
18MP0010094_abnormal_chromosome_stability1.78791920
19MP0003950_abnormal_plasma_membrane1.73390252
20MP0000537_abnormal_urethra_morphology1.72320691
21MP0000462_abnormal_digestive_system1.70819322
22MP0008932_abnormal_embryonic_tissue1.70194136
23MP0004084_abnormal_cardiac_muscle1.60461694
24MP0002877_abnormal_melanocyte_morpholog1.59673010
25MP0001730_embryonic_growth_arrest1.57005861
26MP0002084_abnormal_developmental_patter1.56926473
27MP0003941_abnormal_skin_development1.56415865
28MP0003718_maternal_effect1.55756178
29MP0001849_ear_inflammation1.54494019
30MP0002085_abnormal_embryonic_tissue1.50825659
31MP0001661_extended_life_span1.47503231
32MP0008877_abnormal_DNA_methylation1.44476462
33MP0000566_synostosis1.42885217
34MP0009053_abnormal_anal_canal1.42514705
35MP0000762_abnormal_tongue_morphology1.41602674
36MP0000383_abnormal_hair_follicle1.39946866
37MP0010678_abnormal_skin_adnexa1.38915672
38MP0001485_abnormal_pinna_reflex1.35646561
39MP0005023_abnormal_wound_healing1.32799974
40MP0000428_abnormal_craniofacial_morphol1.30953119
41MP0000534_abnormal_ureter_morphology1.30369154
42MP0000350_abnormal_cell_proliferation1.29667623
43MP0003119_abnormal_digestive_system1.29144122
44MP0001697_abnormal_embryo_size1.28639792
45MP0008438_abnormal_cutaneous_collagen1.28215606
46MP0003878_abnormal_ear_physiology1.26965093
47MP0005377_hearing/vestibular/ear_phenot1.26965093
48MP0005380_embryogenesis_phenotype1.25621153
49MP0001672_abnormal_embryogenesis/_devel1.25621153
50MP0001299_abnormal_eye_distance/1.25163200
51MP0004885_abnormal_endolymph1.24661575
52MP0003755_abnormal_palate_morphology1.23504015
53MP0003385_abnormal_body_wall1.22522844
54MP0000751_myopathy1.21626617
55MP0002938_white_spotting1.20463260
56MP0001293_anophthalmia1.20311392
57MP0003890_abnormal_embryonic-extraembry1.20199865
58MP0008007_abnormal_cellular_replicative1.19528740
59MP0010352_gastrointestinal_tract_polyps1.18705907
60MP0005330_cardiomyopathy1.18629747
61MP0002210_abnormal_sex_determination1.15955946
62MP0002060_abnormal_skin_morphology1.15402311
63MP0005408_hypopigmentation1.15155222
64MP0003567_abnormal_fetal_cardiomyocyte1.14598042
65MP0001346_abnormal_lacrimal_gland1.13826476
66MP0005171_absent_coat_pigmentation1.13769233
67MP0008260_abnormal_autophagy1.10737903
68MP0004197_abnormal_fetal_growth/weight/1.09864540
69MP0000432_abnormal_head_morphology1.09694395
70MP0003566_abnormal_cell_adhesion1.08965462
71MP0004133_heterotaxia1.08866049
72MP0000749_muscle_degeneration1.08042942
73MP0000516_abnormal_urinary_system1.07471442
74MP0005367_renal/urinary_system_phenotyp1.07471442
75MP0004185_abnormal_adipocyte_glucose1.07034573
76MP0004145_abnormal_muscle_electrophysio1.06514922
77MP0009780_abnormal_chondrocyte_physiolo1.06355162
78MP0002269_muscular_atrophy1.06210762
79MP0002233_abnormal_nose_morphology1.06190523
80MP0003984_embryonic_growth_retardation1.05806622
81MP0000358_abnormal_cell_content/1.04697575
82MP0003806_abnormal_nucleotide_metabolis1.04697415
83MP0008058_abnormal_DNA_repair1.03529033
84MP0002111_abnormal_tail_morphology1.03154751
85MP0005395_other_phenotype1.03100629
86MP0001145_abnormal_male_reproductive1.02773308
87MP0003935_abnormal_craniofacial_develop1.02152908
88MP0002088_abnormal_embryonic_growth/wei1.01807911
89MP0005503_abnormal_tendon_morphology1.00674444
90MP0002086_abnormal_extraembryonic_tissu1.00333636
91MP0003936_abnormal_reproductive_system0.99738327
92MP0003786_premature_aging0.99703778
93MP0005508_abnormal_skeleton_morphology0.99034352
94MP0003121_genomic_imprinting0.98903322
95MP0003283_abnormal_digestive_organ0.97817889
96MP0004264_abnormal_extraembryonic_tissu0.97530157
97MP0001915_intracranial_hemorrhage0.97316677
98MP0000653_abnormal_sex_gland0.96171647
99MP0009384_cardiac_valve_regurgitation0.96000006
100MP0002092_abnormal_eye_morphology0.95747781
101MP0006138_congestive_heart_failure0.95671346
102MP0009672_abnormal_birth_weight0.94445837
103MP0005197_abnormal_uvea_morphology0.94373146
104MP0010234_abnormal_vibrissa_follicle0.93526341
105MP0010307_abnormal_tumor_latency0.92065917
106MP0006054_spinal_hemorrhage0.91587930
107MP0000920_abnormal_myelination0.91028701
108MP0003091_abnormal_cell_migration0.90803203
109MP0002080_prenatal_lethality0.90293574
110MP0003942_abnormal_urinary_system0.89969916
111MP0004134_abnormal_chest_morphology0.89339226
112MP0002697_abnormal_eye_size0.89282145
113MP0006072_abnormal_retinal_apoptosis0.88986876
114MP0004087_abnormal_muscle_fiber0.87894451
115MP0005501_abnormal_skin_physiology0.87647001
116MP0001286_abnormal_eye_development0.87045621
117MP0001929_abnormal_gametogenesis0.86935443
118MP0004233_abnormal_muscle_weight0.86917387
119MP0000613_abnormal_salivary_gland0.86851473
120MP0002249_abnormal_larynx_morphology0.86845537
121MP0009250_abnormal_appendicular_skeleto0.86799951
122MP0002116_abnormal_craniofacial_bone0.86030627
123MP0004043_abnormal_pH_regulation0.85872418
124MP0005076_abnormal_cell_differentiation0.84783315
125MP0000733_abnormal_muscle_development0.84178402
126MP0005451_abnormal_body_composition0.82141281
127MP0004036_abnormal_muscle_relaxation0.81993152
128MP0008004_abnormal_stomach_pH0.81347321
129MP0010630_abnormal_cardiac_muscle0.80837564
130MP0003186_abnormal_redox_activity0.80642793
131MP0000647_abnormal_sebaceous_gland0.80201840
132MP0003221_abnormal_cardiomyocyte_apopto0.79366397
133MP0002234_abnormal_pharynx_morphology0.76924515
134MP0001879_abnormal_lymphatic_vessel0.76595423
135MP0005275_abnormal_skin_tensile0.76246802
136MP0004215_abnormal_myocardial_fiber0.75896181
137MP0005621_abnormal_cell_physiology0.74706798
138MP0005193_abnormal_anterior_eye0.73950219
139MP0005384_cellular_phenotype0.72132359
140MP0000003_abnormal_adipose_tissue0.72008733
141MP0000313_abnormal_cell_death0.70460240

Predicted human phenotypes

RankGene SetZ-score
1Ulnar claw (HP:0001178)6.45687112
2Segmental peripheral demyelination/remyelination (HP:0003481)5.39511550
3Insidious onset (HP:0003587)4.48830794
4Termporal pattern (HP:0011008)4.48830794
5Esophageal atresia (HP:0002032)3.30490502
6Protrusio acetabuli (HP:0003179)3.26981729
7Peripheral hypomyelination (HP:0007182)3.14456873
8Impaired proprioception (HP:0010831)3.13618588
9Abnormality of the labia minora (HP:0012880)2.99926982
10Short nail (HP:0001799)2.95299678
11Breast hypoplasia (HP:0003187)2.89654746
12Osteolytic defects of the phalanges of the hand (HP:0009771)2.83829096
13Osteolytic defects of the hand bones (HP:0009699)2.83829096
14Abnormal sex determination (HP:0012244)2.77973947
15Sex reversal (HP:0012245)2.77973947
16Upper limb muscle weakness (HP:0003484)2.68649012
17Decreased number of large peripheral myelinated nerve fibers (HP:0003387)2.57712256
18Abnormality of the umbilical cord (HP:0010881)2.52650850
19Onion bulb formation (HP:0003383)2.51877128
20Irregular epiphyses (HP:0010582)2.51582230
21Adrenal hypoplasia (HP:0000835)2.50295653
22Neoplasm of the oral cavity (HP:0100649)2.46734985
23Gastrointestinal atresia (HP:0002589)2.45037069
24Action tremor (HP:0002345)2.43144152
25Hypoplastic ischia (HP:0003175)2.42350222
26Steppage gait (HP:0003376)2.41461590
27Stenosis of the external auditory canal (HP:0000402)2.40581814
28Deviation of the thumb (HP:0009603)2.40442074
29Absent radius (HP:0003974)2.39404736
30Arterial tortuosity (HP:0005116)2.34567109
31Ankle contracture (HP:0006466)2.34057058
32Single umbilical artery (HP:0001195)2.33593865
33Abnormality of the fetal cardiovascular system (HP:0010948)2.33593865
34Abnormal umbilical cord blood vessels (HP:0011403)2.33593865
35Carpal bone hypoplasia (HP:0001498)2.33139546
36Abnormality of glycolysis (HP:0004366)2.30771852
37Shawl scrotum (HP:0000049)2.30419244
38Male infertility (HP:0003251)2.29993808
39Hypoplasia of the uterus (HP:0000013)2.28921416
40Increased nuchal translucency (HP:0010880)2.26658228
41Absent forearm bone (HP:0003953)2.25304037
42Aplasia involving forearm bones (HP:0009822)2.25304037
43Spinal rigidity (HP:0003306)2.24747617
44Microglossia (HP:0000171)2.24167025
45Increased CSF protein (HP:0002922)2.23677797
46Vertebral compression fractures (HP:0002953)2.22158920
47Decreased number of peripheral myelinated nerve fibers (HP:0003380)2.22001964
48Reduced subcutaneous adipose tissue (HP:0003758)2.21453280
49Ependymoma (HP:0002888)2.20367759
50Birth length less than 3rd percentile (HP:0003561)2.20332728
51Vascular tortuosity (HP:0004948)2.19903163
52Delayed epiphyseal ossification (HP:0002663)2.19649634
53Entropion (HP:0000621)2.19137770
54Abnormality of the salivary glands (HP:0010286)2.18048830
55Abnormality of the ischium (HP:0003174)2.17761347
56Foot dorsiflexor weakness (HP:0009027)2.13821027
57Increased serum pyruvate (HP:0003542)2.13164698
58Decreased motor nerve conduction velocity (HP:0003431)2.12006327
59Chromsome breakage (HP:0040012)2.08991136
60Proximal placement of thumb (HP:0009623)2.06826750
61Ulnar bowing (HP:0003031)2.06514121
62Hammertoe (HP:0001765)2.05793555
63Increased connective tissue (HP:0009025)2.04813029
64Atrophic scars (HP:0001075)2.03750150
65Abnormality of the distal phalanges of the toes (HP:0010182)2.01851404
66Abnormalities of placenta or umbilical cord (HP:0001194)2.01393041
67Cerebral hypomyelination (HP:0006808)2.00113544
68Abnormality of the foot musculature (HP:0001436)2.00091046
69Aplasia/Hypoplasia involving the carpal bones (HP:0006502)1.98691165
70Hypoplasia of the capital femoral epiphysis (HP:0003090)1.97562871
71Shoulder girdle muscle weakness (HP:0003547)1.97176526
72Synostosis of carpal bones (HP:0005048)1.97080972
73Small epiphyses (HP:0010585)1.96549179
74Vertebral clefting (HP:0008428)1.96350316
75Facial cleft (HP:0002006)1.94621352
76Abnormality of cochlea (HP:0000375)1.93511844
77Chromosomal breakage induced by crosslinking agents (HP:0003221)1.93242569
78Ankyloglossia (HP:0010296)1.92979478
79Abnormality of the vocal cords (HP:0008777)1.91669231
80Missing ribs (HP:0000921)1.91214735
81Epiphyseal dysplasia (HP:0002656)1.91191655
82Secondary amenorrhea (HP:0000869)1.90913346
83Limb-girdle muscle atrophy (HP:0003797)1.90659718
84Medulloblastoma (HP:0002885)1.89848246
85Abnormality of carpal bone ossification (HP:0006257)1.87095338
86Aplasia/hypoplasia of the uterus (HP:0008684)1.86623010
87Abnormality of the intrinsic pathway (HP:0010989)1.86066872
88Abnormality of the acetabulum (HP:0003170)1.83620568
89Astrocytoma (HP:0009592)1.82141814
90Abnormality of the astrocytes (HP:0100707)1.82141814
91Spastic diplegia (HP:0001264)1.82111851
92Right ventricular cardiomyopathy (HP:0011663)1.81957706
93Cortical dysplasia (HP:0002539)1.80966996
94Insomnia (HP:0100785)1.79865052
95Abnormality of oral frenula (HP:0000190)1.79348182
96Rib fusion (HP:0000902)1.78864193
97Aplasia/hypoplasia of the humerus (HP:0006507)1.78107255
98Morphological abnormality of the inner ear (HP:0011390)1.78001830
99Supernumerary spleens (HP:0009799)1.77364600
100Papillary thyroid carcinoma (HP:0002895)1.75698563
101Elbow flexion contracture (HP:0002987)1.75226150
102Aortic dissection (HP:0002647)1.74507515
103Premature skin wrinkling (HP:0100678)1.74417092
104Increased mean platelet volume (HP:0011877)1.74343270
105Syringomyelia (HP:0003396)1.73835380
106Spinal cord lesions (HP:0100561)1.73835380
107Short humerus (HP:0005792)1.73601732
108Abnormal auditory evoked potentials (HP:0006958)1.73159084
109Trismus (HP:0000211)1.73017903
110Cervical subluxation (HP:0003308)1.72011399
111Premature rupture of membranes (HP:0001788)1.71483063
112Abnormality of the phalanges of the 2nd finger (HP:0009541)1.71366874
113Pterygium (HP:0001059)1.70785874
114Wormian bones (HP:0002645)1.70325350
115Natal tooth (HP:0000695)1.69277945
116Abnormality of pain sensation (HP:0010832)1.68886800
117Impaired pain sensation (HP:0007328)1.68886800
118Hyperacusis (HP:0010780)1.68159662
119Glioma (HP:0009733)1.68068460
120Hip contracture (HP:0003273)1.67724284
121Aplasia/Hypoplasia of the pubic bone (HP:0009104)1.67710494
122Breech presentation (HP:0001623)1.66714381
123Fragile skin (HP:0001030)1.66056921
12411 pairs of ribs (HP:0000878)1.65974809
125Abnormal ossification of hand bones (HP:0005921)1.65270476
126Spinal cord compression (HP:0002176)1.64885628
127Abnormality of the calcaneus (HP:0008364)1.64853288
128Overlapping toe (HP:0001845)1.64774173
129Cardiovascular calcification (HP:0011915)1.64766482
130Milia (HP:0001056)1.64548237
131Flat capital femoral epiphysis (HP:0003370)1.64158101
132Selective tooth agenesis (HP:0001592)1.63880351
133Progressive muscle weakness (HP:0003323)1.63479542
134Aplasia/Hypoplasia of the sternum (HP:0006714)1.63410040
135Achilles tendon contracture (HP:0001771)1.63046388
136Abnormality of chromosome stability (HP:0003220)1.62765174
137Muscle fiber splitting (HP:0003555)1.62252239
138Abnormal lung lobation (HP:0002101)1.62211124
139Mild short stature (HP:0003502)1.62177926
140Postural tremor (HP:0002174)1.62055769
141Aortic aneurysm (HP:0004942)1.62015435
142Aplasia/Hypoplasia of the sacrum (HP:0008517)1.61912018
143Meckel diverticulum (HP:0002245)1.61613864
144Small intestinal stenosis (HP:0012848)1.61465530
145Duodenal stenosis (HP:0100867)1.61465530
146Patellar aplasia (HP:0006443)1.61435193
147Aplasia involving bones of the extremities (HP:0009825)1.60933070
148Aplasia involving bones of the upper limbs (HP:0009823)1.60933070
149Aplasia of the phalanges of the hand (HP:0009802)1.60933070
150Ureteral duplication (HP:0000073)1.60623850
151Abnormality of the preputium (HP:0100587)1.60474068
152Abnormality of the proximal phalanges of the hand (HP:0009834)1.60411425
153Abnormality of the tricuspid valve (HP:0001702)1.60027968
154Distal lower limb amyotrophy (HP:0008944)1.59370485
155Hypoalphalipoproteinemia (HP:0003233)1.59280018
156Pelvic girdle muscle weakness (HP:0003749)1.59201812
157Metaphyseal cupping (HP:0003021)1.58333601
158Lip pit (HP:0100267)1.57886381
159Shallow orbits (HP:0000586)1.57412316
160Rhabdomyosarcoma (HP:0002859)1.56597756
161Hypoplastic labia majora (HP:0000059)1.56346150
162Multiple enchondromatosis (HP:0005701)1.56031646
163Back pain (HP:0003418)1.55920228
164Rough bone trabeculation (HP:0100670)1.55878335
165Abnormal foot bone ossification (HP:0010675)1.55329980
166Neonatal short-limb short stature (HP:0008921)1.55175424
167Aplasia/Hypoplasia of the patella (HP:0006498)1.54688858
168Alacrima (HP:0000522)1.54676103
169Limited hip movement (HP:0008800)1.53725157
170Duplication of thumb phalanx (HP:0009942)1.53398709
171Abnormality of dentin (HP:0010299)1.53045614
172Nephroblastoma (Wilms tumor) (HP:0002667)1.52985319
173Delayed cranial suture closure (HP:0000270)1.52903336
174Abnormality of methionine metabolism (HP:0010901)1.52803957
175Carpal synostosis (HP:0009702)1.52023330
176Septo-optic dysplasia (HP:0100842)1.51582012
177Abnormal vertebral ossification (HP:0100569)1.51479265
178Hypomagnesemia (HP:0002917)1.50585922
179Breast aplasia (HP:0100783)1.50489215
180Biliary tract neoplasm (HP:0100574)1.49822363
181Ectopic kidney (HP:0000086)1.48813518
182Abnormality of the renal collecting system (HP:0004742)1.48659361

Predicted kinase interactions (KEA)

RankGene SetZ-score
1LATS13.65279133
2MST1R3.14097736
3EIF2AK13.03307673
4EPHA22.89290551
5STK38L2.86085930
6STK392.54009706
7BUB12.50941666
8TTK2.43391527
9WEE12.41557153
10LATS22.29088043
11CDC72.26988962
12MET2.22574238
13SCYL22.16565069
14TYRO31.93200207
15AKT31.81324877
16NME21.79323761
17CDK121.70192432
18PNCK1.65613806
19NEK21.59214216
20TTN1.58936291
21PLK41.58647197
22RPS6KB21.58324650
23SRPK11.57892156
24STK31.57323334
25MAP3K121.54844862
26EPHB11.53303235
27MYLK1.49981198
28OXSR11.46117976
29MST41.44777011
30PLK11.41501053
31CHEK21.38865389
32WNK41.35704327
33WNK31.31543842
34ACVR1B1.29623900
35IRAK31.28639652
36PLK31.26709662
37BRSK21.26492155
38EIF2AK31.26491104
39BRSK11.26484100
40NEK91.25795454
41NEK61.25696182
42CDK81.24478769
43NEK11.24199651
44DDR21.23238555
45CDK71.21283199
46MELK1.11292443
47ICK1.11142443
48MKNK11.10818119
49AURKB1.07008666
50KSR21.05498429
51ZAK1.05095866
52PDK20.99498593
53CHEK10.99481254
54FGFR20.97215819
55VRK20.96435870
56PRKCI0.95780202
57PAK20.95763881
58ERBB40.95486132
59MKNK20.93573976
60BCR0.92135377
61LIMK10.91757849
62PASK0.91014296
63PRKD30.90411401
64DYRK20.89476637
65TESK10.87905003
66WNK10.87661294
67SMG10.87085968
68MAP3K80.86024212
69FER0.85840767
70MAPKAPK30.84980613
71PAK40.84516140
72BRD40.84189843
73TSSK60.81100019
74TRIM280.79751599
75TESK20.79504241
76NUAK10.78993153
77ILK0.78715556
78BMX0.78426806
79ATR0.77054843
80ATM0.76386080
81MTOR0.74760247
82TAF10.74006199
83PBK0.73473193
84AURKA0.72135185
85ABL20.71421809
86CCNB10.71409676
87ALK0.70110171
88ERBB30.69740890
89ARAF0.69585566
90CDK20.68351228
91TGFBR10.67152531
92PTK20.66346536
93FLT30.65630191
94PDGFRA0.65028827
95DYRK30.64608841
96BRAF0.64550363
97MAP3K20.64189227
98RET0.61800547
99CSNK1E0.59739288
100CDK10.59535795
101IRAK10.58983742
102STK40.58212477
103PDK40.57888653
104PDK30.57888653
105MAP3K30.57723950
106TIE10.57393567
107TGFBR20.56819292
108ROCK20.56677926
109FGFR10.56484357
110EIF2AK20.56477645
111CSNK1A1L0.55778720
112EPHB20.54881653
113MOS0.54643913
114AKT20.54417862
115STK100.52735778
116CLK10.51224719
117PDGFRB0.50602148
118GSK3A0.50569037
119CSNK1D0.49965040
120DMPK0.49804901
121STK160.49051924
122VRK10.48799188
123EEF2K0.48764617
124ROCK10.48646439
125CSNK1G10.47889723
126PAK30.47455760
127MUSK0.44953620
128CDK60.44067572
129STK240.43714398
130PAK10.42801520
131DAPK30.42069421
132TRPM70.40667767
133RPS6KA40.39099122
134NTRK10.38232844
135LMTK20.38106746
136MAP3K60.37160907
137KSR10.36834126
138CDK40.35155538
139RAF10.34423143
140CDK90.33356527
141CSNK2A20.31754803
142MAP3K50.31263519
143TRIB30.30038198

Predicted pathways (KEGG)

RankGene SetZ-score
1Cell cycle_Homo sapiens_hsa041102.87193060
2Ribosome biogenesis in eukaryotes_Homo sapiens_hsa030082.85517880
3RNA transport_Homo sapiens_hsa030132.76927514
4RNA polymerase_Homo sapiens_hsa030202.76753332
5Mismatch repair_Homo sapiens_hsa034302.57525878
6Basal transcription factors_Homo sapiens_hsa030222.48959561
7ECM-receptor interaction_Homo sapiens_hsa045122.47131255
8Terpenoid backbone biosynthesis_Homo sapiens_hsa009002.44815885
9Citrate cycle (TCA cycle)_Homo sapiens_hsa000202.36203403
10DNA replication_Homo sapiens_hsa030302.05652938
11Nucleotide excision repair_Homo sapiens_hsa034202.03635874
12RNA degradation_Homo sapiens_hsa030182.03583847
13Hippo signaling pathway_Homo sapiens_hsa043901.99890643
14Tight junction_Homo sapiens_hsa045301.93156281
15Spliceosome_Homo sapiens_hsa030401.87146528
16TGF-beta signaling pathway_Homo sapiens_hsa043501.83789027
172-Oxocarboxylic acid metabolism_Homo sapiens_hsa012101.80914079
18mRNA surveillance pathway_Homo sapiens_hsa030151.79193050
19Homologous recombination_Homo sapiens_hsa034401.77992842
20Biosynthesis of amino acids_Homo sapiens_hsa012301.71967318
21Pyruvate metabolism_Homo sapiens_hsa006201.70068825
22Ether lipid metabolism_Homo sapiens_hsa005651.67284650
23Non-homologous end-joining_Homo sapiens_hsa034501.64527879
24Vitamin B6 metabolism_Homo sapiens_hsa007501.63895725
25Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa045501.61532518
26Small cell lung cancer_Homo sapiens_hsa052221.61458240
27Hedgehog signaling pathway_Homo sapiens_hsa043401.60702495
28Fanconi anemia pathway_Homo sapiens_hsa034601.60255910
29Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa009701.55385005
30Adherens junction_Homo sapiens_hsa045201.47829445
31Ubiquitin mediated proteolysis_Homo sapiens_hsa041201.46411855
32Carbon metabolism_Homo sapiens_hsa012001.45115715
33Basal cell carcinoma_Homo sapiens_hsa052171.44962458
34MicroRNAs in cancer_Homo sapiens_hsa052061.43421999
35p53 signaling pathway_Homo sapiens_hsa041151.41812855
36Cysteine and methionine metabolism_Homo sapiens_hsa002701.38782341
37Pentose phosphate pathway_Homo sapiens_hsa000301.35766415
38Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa054121.34756518
39Oocyte meiosis_Homo sapiens_hsa041141.34009433
40Focal adhesion_Homo sapiens_hsa045101.29396421
41Progesterone-mediated oocyte maturation_Homo sapiens_hsa049141.26041368
42One carbon pool by folate_Homo sapiens_hsa006701.26025828
43Protein digestion and absorption_Homo sapiens_hsa049741.22574060
44Glycolysis / Gluconeogenesis_Homo sapiens_hsa000101.16810381
45alpha-Linolenic acid metabolism_Homo sapiens_hsa005921.12446175
46Linoleic acid metabolism_Homo sapiens_hsa005911.11311196
47N-Glycan biosynthesis_Homo sapiens_hsa005101.10967701
48Glyoxylate and dicarboxylate metabolism_Homo sapiens_hsa006301.09215603
49Prostate cancer_Homo sapiens_hsa052151.07372702
50Base excision repair_Homo sapiens_hsa034101.06824717
51Sphingolipid metabolism_Homo sapiens_hsa006000.99933222
52Central carbon metabolism in cancer_Homo sapiens_hsa052300.94058068
53Wnt signaling pathway_Homo sapiens_hsa043100.93628514
54Glycosphingolipid biosynthesis - globo series_Homo sapiens_hsa006030.93175803
55Protein processing in endoplasmic reticulum_Homo sapiens_hsa041410.91649544
56Pyrimidine metabolism_Homo sapiens_hsa002400.91598218
57Steroid biosynthesis_Homo sapiens_hsa001000.90441075
58PI3K-Akt signaling pathway_Homo sapiens_hsa041510.90019245
59Thyroid cancer_Homo sapiens_hsa052160.89333926
60Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa054100.88389816
61Phenylalanine, tyrosine and tryptophan biosynthesis_Homo sapiens_hsa004000.88104415
62Renal cell carcinoma_Homo sapiens_hsa052110.87449985
63Sulfur relay system_Homo sapiens_hsa041220.86606176
64Selenocompound metabolism_Homo sapiens_hsa004500.85998726
65Dorso-ventral axis formation_Homo sapiens_hsa043200.85343245
66Glycosylphosphatidylinositol(GPI)-anchor biosynthesis_Homo sapiens_hsa005630.85071485
67Ubiquinone and other terpenoid-quinone biosynthesis_Homo sapiens_hsa001300.82310744
68Axon guidance_Homo sapiens_hsa043600.81209410
69Proteoglycans in cancer_Homo sapiens_hsa052050.80050832
70Melanoma_Homo sapiens_hsa052180.78923368
71Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa005200.78613500
72Galactose metabolism_Homo sapiens_hsa000520.78477662
73Purine metabolism_Homo sapiens_hsa002300.78194954
74Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa010400.77660149
75Pathways in cancer_Homo sapiens_hsa052000.77578805
76Circadian rhythm_Homo sapiens_hsa047100.76585412
77Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa005340.76554172
78Bladder cancer_Homo sapiens_hsa052190.74901677
79Propanoate metabolism_Homo sapiens_hsa006400.74777112
80Ovarian steroidogenesis_Homo sapiens_hsa049130.73709335
81Viral carcinogenesis_Homo sapiens_hsa052030.73006696
82Colorectal cancer_Homo sapiens_hsa052100.70991073
83mTOR signaling pathway_Homo sapiens_hsa041500.70818345
84Endometrial cancer_Homo sapiens_hsa052130.69856237
85Arachidonic acid metabolism_Homo sapiens_hsa005900.67934770
86Glutathione metabolism_Homo sapiens_hsa004800.67477485
87Cell adhesion molecules (CAMs)_Homo sapiens_hsa045140.66323196
88Glycine, serine and threonine metabolism_Homo sapiens_hsa002600.66143784
89Dilated cardiomyopathy_Homo sapiens_hsa054140.64875105
90Notch signaling pathway_Homo sapiens_hsa043300.64414963
91Chronic myeloid leukemia_Homo sapiens_hsa052200.64111425
92Amoebiasis_Homo sapiens_hsa051460.59140070
93Arginine and proline metabolism_Homo sapiens_hsa003300.58928623
94Regulation of actin cytoskeleton_Homo sapiens_hsa048100.58709897
95Sulfur metabolism_Homo sapiens_hsa009200.57523046
96Porphyrin and chlorophyll metabolism_Homo sapiens_hsa008600.52918643
97Thyroid hormone signaling pathway_Homo sapiens_hsa049190.52578281
98Bacterial invasion of epithelial cells_Homo sapiens_hsa051000.51978742
99Protein export_Homo sapiens_hsa030600.50231026
100Maturity onset diabetes of the young_Homo sapiens_hsa049500.49779410
101Pancreatic cancer_Homo sapiens_hsa052120.48179860
102Choline metabolism in cancer_Homo sapiens_hsa052310.47186060
103Tyrosine metabolism_Homo sapiens_hsa003500.46916756
104Proteasome_Homo sapiens_hsa030500.46244190
105Fatty acid metabolism_Homo sapiens_hsa012120.45227503
106Phenylalanine metabolism_Homo sapiens_hsa003600.44813022
107Longevity regulating pathway - mammal_Homo sapiens_hsa042110.43378301
108Regulation of autophagy_Homo sapiens_hsa041400.43315843
109Arginine biosynthesis_Homo sapiens_hsa002200.42510258
110FoxO signaling pathway_Homo sapiens_hsa040680.42187280
111Valine, leucine and isoleucine degradation_Homo sapiens_hsa002800.42151261
112ErbB signaling pathway_Homo sapiens_hsa040120.42090420
113Ras signaling pathway_Homo sapiens_hsa040140.42016196
114Epstein-Barr virus infection_Homo sapiens_hsa051690.41906848
115HTLV-I infection_Homo sapiens_hsa051660.41777395
116Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa002500.41261816
117Transcriptional misregulation in cancer_Homo sapiens_hsa052020.40553557
118Huntingtons disease_Homo sapiens_hsa050160.40361730
119AMPK signaling pathway_Homo sapiens_hsa041520.39854498
120Vibrio cholerae infection_Homo sapiens_hsa051100.39085454
121Fatty acid elongation_Homo sapiens_hsa000620.38029671
122Metabolic pathways_Homo sapiens_hsa011000.37258335
123Shigellosis_Homo sapiens_hsa051310.36809240
124Alcoholism_Homo sapiens_hsa050340.36197172
125Fructose and mannose metabolism_Homo sapiens_hsa000510.35960689
126Pathogenic Escherichia coli infection_Homo sapiens_hsa051300.35833411
127Viral myocarditis_Homo sapiens_hsa054160.35247401
128Pantothenate and CoA biosynthesis_Homo sapiens_hsa007700.33037293
129Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa005320.31573611
130Estrogen signaling pathway_Homo sapiens_hsa049150.31405944
131Inositol phosphate metabolism_Homo sapiens_hsa005620.31329999
132Folate biosynthesis_Homo sapiens_hsa007900.30318287
133Glycerophospholipid metabolism_Homo sapiens_hsa005640.30244219
134Ribosome_Homo sapiens_hsa030100.29527112
135Lysine degradation_Homo sapiens_hsa003100.29429671

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