Rank | Gene Set | Z-score |
---|---|---|
1 | hippo signaling (GO:0035329) | 4.34103575 |
2 | polarized epithelial cell differentiation (GO:0030859) | 3.89683524 |
3 | retina vasculature morphogenesis in camera-type eye (GO:0061299) | 3.71062230 |
4 | paraxial mesoderm development (GO:0048339) | 3.63266047 |
5 | gap junction assembly (GO:0016264) | 3.59749288 |
6 | planar cell polarity pathway involved in neural tube closure (GO:0090179) | 3.46866710 |
7 | bundle of His cell to Purkinje myocyte communication (GO:0086069) | 3.44776100 |
8 | morphogenesis of an epithelial sheet (GO:0002011) | 3.37608997 |
9 | establishment of apical/basal cell polarity (GO:0035089) | 3.36981139 |
10 | desmosome organization (GO:0002934) | 3.36294625 |
11 | insulin-like growth factor receptor signaling pathway (GO:0048009) | 3.35609598 |
12 | regulation of establishment of planar polarity involved in neural tube closure (GO:0090178) | 3.34905732 |
13 | regulation of hippo signaling (GO:0035330) | 3.33498439 |
14 | dichotomous subdivision of an epithelial terminal unit (GO:0060600) | 3.28076815 |
15 | melanin biosynthetic process (GO:0042438) | 3.20892130 |
16 | hemidesmosome assembly (GO:0031581) | 3.20512485 |
17 | glucocorticoid receptor signaling pathway (GO:0042921) | 3.20023820 |
18 | establishment of nucleus localization (GO:0040023) | 3.18723567 |
19 | negative regulation of catenin import into nucleus (GO:0035414) | 3.15720227 |
20 | axon extension involved in axon guidance (GO:0048846) | 3.15711484 |
21 | neuron projection extension involved in neuron projection guidance (GO:1902284) | 3.15711484 |
22 | peptidyl-lysine dimethylation (GO:0018027) | 3.12335882 |
23 | renal system development (GO:0072001) | 3.10284265 |
24 | pore complex assembly (GO:0046931) | 3.04595759 |
25 | regulation of SMAD protein import into nucleus (GO:0060390) | 2.98554203 |
26 | negative regulation of keratinocyte proliferation (GO:0010839) | 2.98371026 |
27 | COPI coating of Golgi vesicle (GO:0048205) | 2.96738548 |
28 | Golgi transport vesicle coating (GO:0048200) | 2.96738548 |
29 | positive regulation of SMAD protein import into nucleus (GO:0060391) | 2.96363108 |
30 | protein retention in ER lumen (GO:0006621) | 2.95663695 |
31 | cell migration involved in sprouting angiogenesis (GO:0002042) | 2.95043479 |
32 | establishment of monopolar cell polarity (GO:0061162) | 2.94876598 |
33 | establishment or maintenance of monopolar cell polarity (GO:0061339) | 2.94876598 |
34 | cytoplasmic mRNA processing body assembly (GO:0033962) | 2.93902389 |
35 | endocardial cushion development (GO:0003197) | 2.93216803 |
36 | * embryonic foregut morphogenesis (GO:0048617) | 2.92154430 |
37 | cell adhesion mediated by integrin (GO:0033627) | 2.91343306 |
38 | pre-miRNA processing (GO:0031054) | 2.91039305 |
39 | glomerular visceral epithelial cell development (GO:0072015) | 2.88613728 |
40 | maintenance of protein localization in endoplasmic reticulum (GO:0035437) | 2.88320798 |
41 | regulation of single stranded viral RNA replication via double stranded DNA intermediate (GO:0045091 | 2.88318549 |
42 | plasma membrane repair (GO:0001778) | 2.87656063 |
43 | wound healing, spreading of epidermal cells (GO:0035313) | 2.86866611 |
44 | response to lipoprotein particle (GO:0055094) | 2.85961197 |
45 | endothelial cell morphogenesis (GO:0001886) | 2.85796365 |
46 | epithelial cell-cell adhesion (GO:0090136) | 2.84846093 |
47 | COPII vesicle coating (GO:0048208) | 2.84291317 |
48 | establishment or maintenance of epithelial cell apical/basal polarity (GO:0045197) | 2.82904993 |
49 | Notch signaling involved in heart development (GO:0061314) | 2.76541289 |
50 | semaphorin-plexin signaling pathway (GO:0071526) | 2.74846589 |
51 | regulation of low-density lipoprotein particle receptor biosynthetic process (GO:0045714) | 2.73359691 |
52 | respiratory tube development (GO:0030323) | 2.72949616 |
53 | melanin metabolic process (GO:0006582) | 2.71966318 |
54 | positive regulation of hormone biosynthetic process (GO:0046886) | 2.70783914 |
55 | retrograde vesicle-mediated transport, Golgi to ER (GO:0006890) | 2.70215746 |
56 | renal filtration (GO:0097205) | 2.67839455 |
57 | lymph vessel development (GO:0001945) | 2.67811660 |
58 | regulation of transforming growth factor beta2 production (GO:0032909) | 2.66204318 |
59 | * cell surface receptor signaling pathway involved in heart development (GO:0061311) | 2.64915799 |
60 | regulation of catenin import into nucleus (GO:0035412) | 2.63938399 |
61 | basement membrane organization (GO:0071711) | 2.63637560 |
62 | vascular endothelial growth factor signaling pathway (GO:0038084) | 2.62259148 |
63 | NLS-bearing protein import into nucleus (GO:0006607) | 2.62125446 |
64 | vesicle coating (GO:0006901) | 2.62098530 |
65 | nuclear pore complex assembly (GO:0051292) | 2.60854799 |
66 | glomerular epithelial cell development (GO:0072310) | 2.60671818 |
67 | * gastrulation with mouth forming second (GO:0001702) | 2.59986032 |
68 | * negative regulation of chondrocyte differentiation (GO:0032331) | 2.58899740 |
69 | surfactant homeostasis (GO:0043129) | 2.58824052 |
70 | corticosteroid receptor signaling pathway (GO:0031958) | 2.57691640 |
71 | secondary metabolite biosynthetic process (GO:0044550) | 2.57084213 |
72 | negative regulation of vascular endothelial growth factor receptor signaling pathway (GO:0030948) | 2.55864488 |
73 | * adherens junction assembly (GO:0034333) | 2.55610796 |
74 | cell-substrate junction assembly (GO:0007044) | 2.54930561 |
75 | nuclear pore organization (GO:0006999) | 2.54536794 |
76 | collecting duct development (GO:0072044) | 2.52943671 |
77 | cellular response to follicle-stimulating hormone stimulus (GO:0071372) | 2.52007963 |
78 | G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger (GO:0007199 | 2.51867466 |
79 | chondrocyte proliferation (GO:0035988) | 2.50983512 |
80 | body morphogenesis (GO:0010171) | 2.50634354 |
81 | blood vessel endothelial cell migration (GO:0043534) | 2.47771983 |
82 | protein localization to endosome (GO:0036010) | 2.47480016 |
83 | heart morphogenesis (GO:0003007) | 2.47120852 |
84 | establishment or maintenance of bipolar cell polarity (GO:0061245) | 2.47009180 |
85 | establishment or maintenance of apical/basal cell polarity (GO:0035088) | 2.47009180 |
86 | outer ear morphogenesis (GO:0042473) | 2.46912999 |
87 | negative regulation of vascular permeability (GO:0043116) | 2.46526922 |
88 | apical protein localization (GO:0045176) | 2.45601470 |
89 | mesodermal cell differentiation (GO:0048333) | 2.45575814 |
90 | * cytoskeletal anchoring at plasma membrane (GO:0007016) | 2.44918831 |
91 | stress fiber assembly (GO:0043149) | 2.43714682 |
92 | ganglion development (GO:0061548) | 2.43545814 |
93 | anatomical structure regression (GO:0060033) | 2.43429053 |
94 | Wnt signaling pathway, planar cell polarity pathway (GO:0060071) | 2.41775782 |
95 | * dorsal/ventral axis specification (GO:0009950) | 2.41266506 |
96 | negative regulation of DNA repair (GO:0045738) | 2.41208381 |
97 | membrane protein ectodomain proteolysis (GO:0006509) | 2.41117457 |
98 | establishment of tissue polarity (GO:0007164) | 2.40251501 |
99 | establishment of planar polarity (GO:0001736) | 2.40251501 |
100 | regulation of establishment of planar polarity (GO:0090175) | 2.39064358 |
101 | anterior/posterior axis specification, embryo (GO:0008595) | 2.38939288 |
102 | negative regulation of fatty acid transport (GO:2000192) | 2.38874137 |
103 | cellular protein complex localization (GO:0034629) | 2.37864974 |
104 | ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway (GO:004316 | 2.36906514 |
105 | artery development (GO:0060840) | 2.36887705 |
106 | endodermal cell differentiation (GO:0035987) | 2.36284738 |
107 | asymmetric protein localization (GO:0008105) | 2.36035073 |
108 | lymphangiogenesis (GO:0001946) | 2.34213088 |
109 | non-canonical Wnt signaling pathway (GO:0035567) | 2.34084825 |
110 | notochord development (GO:0030903) | 2.33806777 |
111 | mitotic sister chromatid cohesion (GO:0007064) | 2.32799722 |
112 | regulation of transcription from RNA polymerase II promoter in response to oxidative stress (GO:0043 | 2.32287502 |
113 | protein complex localization (GO:0031503) | 2.31015227 |
114 | mRNA stabilization (GO:0048255) | 2.30241669 |
115 | RNA stabilization (GO:0043489) | 2.30241669 |
116 | protein heterotrimerization (GO:0070208) | 2.30096992 |
117 | regulation of attachment of spindle microtubules to kinetochore (GO:0051988) | 2.29191711 |
118 | germ cell migration (GO:0008354) | 2.29166107 |
119 | regulation of RNA export from nucleus (GO:0046831) | 2.28986915 |
120 | DNA unwinding involved in DNA replication (GO:0006268) | 2.26775133 |
121 | * adherens junction organization (GO:0034332) | 2.26535104 |
122 | branching involved in salivary gland morphogenesis (GO:0060445) | 2.25699987 |
123 | establishment of epithelial cell polarity (GO:0090162) | 2.24388866 |
124 | cellular response to vascular endothelial growth factor stimulus (GO:0035924) | 2.23057070 |
125 | coronary vasculature morphogenesis (GO:0060977) | 2.22947056 |
126 | focal adhesion assembly (GO:0048041) | 2.22705294 |
127 | cell-substrate adherens junction assembly (GO:0007045) | 2.22705294 |
128 | skin morphogenesis (GO:0043589) | 2.21821180 |
129 | positive regulation of glycogen biosynthetic process (GO:0045725) | 2.21421249 |
130 | regulation of cellular response to vascular endothelial growth factor stimulus (GO:1902547) | 2.20826588 |
131 | lateral sprouting from an epithelium (GO:0060601) | 2.20584871 |
132 | positive regulation of nitric-oxide synthase activity (GO:0051000) | 2.20576928 |
133 | receptor catabolic process (GO:0032801) | 2.20474591 |
134 | positive regulation of transcription from RNA polymerase II promoter in response to stress (GO:00360 | 2.20271118 |
135 | barbed-end actin filament capping (GO:0051016) | 2.19533780 |
136 | negative regulation of anoikis (GO:2000811) | 2.18656611 |
137 | collagen metabolic process (GO:0032963) | 2.16941135 |
138 | ephrin receptor signaling pathway (GO:0048013) | 2.16496488 |
139 | multicellular organismal macromolecule metabolic process (GO:0044259) | 2.16399354 |
140 | mitotic cytokinesis (GO:0000281) | 2.16037527 |
141 | regulation of Rac protein signal transduction (GO:0035020) | 2.14865330 |
142 | convergent extension (GO:0060026) | 2.07967344 |
143 | substrate adhesion-dependent cell spreading (GO:0034446) | 2.07966606 |
144 | axis elongation (GO:0003401) | 2.07644268 |
145 | wound healing, spreading of cells (GO:0044319) | 2.06779185 |
146 | multicellular organismal metabolic process (GO:0044236) | 2.05688617 |
147 | collagen catabolic process (GO:0030574) | 2.05169982 |
148 | regulation of metanephric nephron tubule epithelial cell differentiation (GO:0072307) | 2.04589620 |
149 | craniofacial suture morphogenesis (GO:0097094) | 2.01444118 |
150 | peptidyl-proline hydroxylation (GO:0019511) | 2.01275146 |
151 | cell communication by electrical coupling (GO:0010644) | 2.00962609 |
152 | endothelium development (GO:0003158) | 2.00376954 |
153 | ventricular cardiac muscle cell development (GO:0055015) | 2.00084557 |
154 | extracellular matrix disassembly (GO:0022617) | 1.99329838 |
155 | bone remodeling (GO:0046849) | 1.99260651 |
156 | collagen fibril organization (GO:0030199) | 1.99233452 |
157 | regulation of steroid hormone biosynthetic process (GO:0090030) | 1.98880092 |
158 | regulation of keratinocyte proliferation (GO:0010837) | 1.98591331 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TP63_17297297_ChIP-ChIP_HaCaT_Human | 4.58040139 |
2 | * NUCKS1_24931609_ChIP-Seq_HEPATOCYTES_Mouse | 3.58007828 |
3 | EGR1_19374776_ChIP-ChIP_THP-1_Human | 3.40754655 |
4 | CLOCK_20551151_ChIP-Seq_293T_Human | 2.91693103 |
5 | FOXM1_23109430_ChIP-Seq_U2OS_Human | 2.82277282 |
6 | TRIM28_21343339_ChIP-Seq_HEK293_Human | 2.70253053 |
7 | SALL1_21062744_ChIP-ChIP_HESCs_Human | 2.53410020 |
8 | STAT6_21828071_ChIP-Seq_BEAS2B_Human | 2.41063796 |
9 | WT1_20215353_ChIP-ChIP_NEPHRON_PROGENITOR_Mouse | 2.38055927 |
10 | * TCF3_18467660_ChIP-ChIP_MESCs_Mouse | 2.37485603 |
11 | ZFP281_18358816_ChIP-ChIP_MESCs_Mouse | 2.24754466 |
12 | RBPJ_22232070_ChIP-Seq_NCS_Mouse | 2.19456262 |
13 | * EP300_20729851_ChIP-Seq_FORBRAIN_MIDBRAIN_LIMB_HEART_Mouse | 2.16014612 |
14 | ZNF263_19887448_ChIP-Seq_K562_Human | 2.14624425 |
15 | * ZFP281_18757296_ChIP-ChIP_E14_Mouse | 2.10341267 |
16 | RARG_19884340_ChIP-ChIP_MEFs_Mouse | 2.08913258 |
17 | SALL4_18804426_ChIP-ChIP_MESCs_Mouse | 2.07873379 |
18 | CDX2_19796622_ChIP-Seq_MESCs_Mouse | 2.07838664 |
19 | ZIC3_20872845_ChIP-ChIP_MESCs_Mouse | 1.99715394 |
20 | ESR1_15608294_ChIP-ChIP_MCF-7_Human | 1.97338104 |
21 | * DMRT1_23473982_ChIP-Seq_TESTES_Mouse | 1.93635613 |
22 | ZFP281_27345836_Chip-Seq_ESCs_Mouse | 1.93288371 |
23 | KLF6_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.92345016 |
24 | PPARD_23176727_ChIP-Seq_KERATINOCYTES_Mouse | 1.90054376 |
25 | E2F7_22180533_ChIP-Seq_HELA_Human | 1.83401464 |
26 | CEBPD_23245923_ChIP-Seq_MEFs_Mouse | 1.79497180 |
27 | HIF1A_21447827_ChIP-Seq_MCF-7_Human | 1.73322097 |
28 | NANOG_18700969_ChIP-ChIP_MESCs_Mouse | 1.73015961 |
29 | FOXP1_22492998_ChIP-Seq_STRATIUM_Mouse | 1.69582855 |
30 | P300_27058665_Chip-Seq_ZR-75-30cells_Human | 1.68393385 |
31 | SMAD3_22036565_ChIP-Seq_ESCs_Mouse | 1.67650048 |
32 | SMAD4_19686287_ChIP-ChIP_HaCaT_Human | 1.65923616 |
33 | HOXD13_18407260_ChIP-ChIP_DEVELOPING-LIMBS_Mouse | 1.64312174 |
34 | AR_21909140_ChIP-Seq_LNCAP_Human | 1.63013939 |
35 | ZFP322A_24550733_ChIP-Seq_MESCs_Mouse | 1.60888478 |
36 | STAT3_22323479_ChIP-Seq_MACROPHAGE_Mouse | 1.59715993 |
37 | FOXM1_26100407_CHIP-SEQ_Hek293_flp-in_Human | 1.59294098 |
38 | WT1_19549856_ChIP-ChIP_CCG9911_Human | 1.59041590 |
39 | * KDM5B_21448134_ChIP-Seq_MESCs_Mouse | 1.58784101 |
40 | ESR1_21235772_ChIP-Seq_MCF-7_Human | 1.57685695 |
41 | * ISL1_27105846_Chip-Seq_CPCs_Mouse | 1.56436015 |
42 | FOXO3_23340844_ChIP-Seq_DLD1_Human | 1.54781084 |
43 | ZNF217_24962896_ChIP-Seq_MCF-7_Human | 1.54754869 |
44 | ESR2_21235772_ChIP-Seq_MCF-7_Human | 1.53817203 |
45 | * SMARCA4_20176728_ChIP-ChIP_TSCs_Mouse | 1.50578918 |
46 | RUNX2_24764292_ChIP-Seq_MC3T3_Mouse | 1.50493941 |
47 | * KDM2B_26808549_Chip-Seq_K562_Human | 1.49784662 |
48 | KLF4_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.46655983 |
49 | ELK3_25401928_ChIP-Seq_HUVEC_Human | 1.45583261 |
50 | KDM2B_26808549_Chip-Seq_DND41_Human | 1.45545144 |
51 | KDM2B_26808549_Chip-Seq_SUP-B15_Human | 1.45237597 |
52 | ESR1_20079471_ChIP-ChIP_T-47D_Human | 1.43066954 |
53 | CEBPD_21427703_ChIP-Seq_3T3-L1_Mouse | 1.41621201 |
54 | TFAP2C_20629094_ChIP-Seq_MCF-7_Human | 1.41501127 |
55 | NACC1_18358816_ChIP-ChIP_MESCs_Mouse | 1.41375152 |
56 | NRF2_20460467_ChIP-Seq_MEFs_Mouse | 1.40177097 |
57 | NFE2L2_20460467_ChIP-Seq_MEFs_Mouse | 1.40177097 |
58 | ESR1_22446102_ChIP-Seq_UTERUS_Mouse | 1.39928632 |
59 | * EZH2_23942234_ChIP-Seq_MYOBLASTS_AND_MYOTUBES_Mouse | 1.38234019 |
60 | ELF3_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.37752159 |
61 | YAP1_20516196_ChIP-Seq_MESCs_Mouse | 1.37056486 |
62 | KDM2B_26808549_Chip-Seq_JURKAT_Human | 1.36631046 |
63 | * SMAD3_18955504_ChIP-ChIP_HaCaT_Human | 1.36466455 |
64 | * SMAD2_18955504_ChIP-ChIP_HaCaT_Human | 1.36466455 |
65 | EP300_21415370_ChIP-Seq_HL-1_Mouse | 1.35399620 |
66 | BRD4_25478319_ChIP-Seq_HGPS_Human | 1.35329567 |
67 | ATF3_27146783_Chip-Seq_COLON_Human | 1.31783489 |
68 | PPAR_26484153_Chip-Seq_NCI-H1993_Human | 1.31704811 |
69 | POU5F1_18700969_ChIP-ChIP_MESCs_Mouse | 1.30274770 |
70 | TCF3_18692474_ChIP-Seq_MEFs_Mouse | 1.28765112 |
71 | SALL4_18804426_ChIP-ChIP_XEN_Mouse | 1.28051619 |
72 | SMAD_19615063_ChIP-ChIP_OVARY_Human | 1.27984108 |
73 | MYC_22102868_ChIP-Seq_BL_Human | 1.27271530 |
74 | TP53_18474530_ChIP-ChIP_U2OS_Human | 1.26953955 |
75 | KDM2B_26808549_Chip-Seq_SIL-ALL_Human | 1.26406554 |
76 | TRP63_18441228_ChIP-ChIP_KERATINOCYTES_Mouse | 1.24422981 |
77 | RUNX1_27514584_Chip-Seq_MCF-7_Human | 1.23446187 |
78 | TCF21_23034159_ChIP-ChIP_E13_GONADS_Rat | 1.23085145 |
79 | UBF1/2_26484160_Chip-Seq_HMECs_Human | 1.22617233 |
80 | * TCF7_22412390_ChIP-Seq_EML_Mouse | 1.21840518 |
81 | * NFIB_24661679_ChIP-Seq_LUNG_Mouse | 1.21063310 |
82 | CHD1_26751641_Chip-Seq_LNCaP_Human | 1.20060203 |
83 | CTNNB1_20460455_ChIP-Seq_HCT116_Human | 1.19888339 |
84 | * SOX17_20123909_ChIP-Seq_XEN_Mouse | 1.19791266 |
85 | TCF4_18268006_ChIP-ChIP_LS174T_Human | 1.19223396 |
86 | CEBPB_21427703_ChIP-Seq_3T3-L1_Mouse | 1.18656004 |
87 | RACK7_27058665_Chip-Seq_MCF-7_Human | 1.18444408 |
88 | * SOX9_24532713_ChIP-Seq_HFSC_Mouse | 1.18340253 |
89 | SMARCA4_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.17766937 |
90 | FOXP2_23625967_ChIP-Seq_PFSK-1_AND_SK-N-MC_Human | 1.17180709 |
91 | OLIG2_23332759_ChIP-Seq_OLIGODENDROCYTES_Mouse | 1.16999642 |
92 | NANOG_18347094_ChIP-ChIP_MESCs_Mouse | 1.16421222 |
93 | FOXA1_26769127_Chip-Seq_PDAC-Cell_line_Human | 1.15896226 |
94 | KDM2B_26808549_Chip-Seq_HPB-ALL_Human | 1.15520737 |
95 | AR_22383394_ChIP-Seq_PROSTATE_CANCER_Human | 1.15162765 |
96 | TEAD4_22529382_ChIP-Seq_TROPHECTODERM_Mouse | 1.14170506 |
97 | PKCTHETA_26484144_Chip-Seq_BREAST_Human | 1.13888847 |
98 | TBX3_20139965_ChIP-Seq_MESCs_Mouse | 1.12206260 |
99 | STAT3_24763339_ChIP-Seq_IMN-ESCs_Mouse | 1.11941359 |
100 | TBX3_20139965_ChIP-Seq_ESCs_Mouse | 1.11792471 |
101 | CREB1_26743006_Chip-Seq_LNCaP_Human | 1.11711489 |
102 | TCF21_26020271_ChIP-Seq_SMOOTH_MUSCLE_Human | 1.11060387 |
103 | PIAS1_25552417_ChIP-Seq_VCAP_Human | 1.11042109 |
104 | * SOX2_27498859_Chip-Seq_STOMACH_Mouse | 1.10894118 |
105 | * SOX2_18358816_ChIP-ChIP_MESCs_Mouse | 1.06994869 |
106 | AHR_22903824_ChIP-Seq_MCF-7_Human | 1.06880052 |
107 | CREB1_26743006_Chip-Seq_LNCaP-abl_Human | 1.06452306 |
108 | NANOG_21062744_ChIP-ChIP_HESCs_Human | 1.05980767 |
109 | GATA6_25053715_ChIP-Seq_YYC3_Human | 1.05841577 |
110 | * WT1_25993318_ChIP-Seq_PODOCYTE_Human | 1.04927686 |
111 | ZFX_18555785_ChIP-Seq_MESCs_Mouse | 1.03986033 |
112 | POU5F1_18347094_ChIP-ChIP_MESCs_Mouse | 1.03884746 |
113 | TCFAP2C_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 1.03455768 |
114 | RING1B_27294783_Chip-Seq_NPCs_Mouse | 1.02861628 |
115 | PRDM5_23873026_ChIP-Seq_MEFs_Mouse | 1.02581845 |
116 | UBF1/2_26484160_Chip-Seq_HMEC-DERIVED_Human | 1.02152730 |
117 | EOMES_20176728_ChIP-ChIP_TSCs_Mouse | 1.01097909 |
118 | CDX2_20551321_ChIP-Seq_CACO-2_Human | 1.00635110 |
119 | CJUN_26792858_Chip-Seq_BT549_Human | 1.00051121 |
120 | * TBX20_22080862_ChIP-Seq_HEART_Mouse | 0.99031586 |
121 | * TBX20_22328084_ChIP-Seq_HEART_Mouse | 0.99031586 |
122 | PPARG_20176806_ChIP-Seq_3T3-L1_Mouse | 0.98967160 |
123 | ETS2_20176728_ChIP-ChIP_TROPHOBLAST_STEM_CELLS_Mouse | 0.98085168 |
124 | FOXM1_26456572_ChIP-Seq_MCF-7_Human | 0.97492985 |
125 | SOX2_19030024_ChIP-ChIP_MESCs_Mouse | 0.97090214 |
126 | SOX9_26525672_Chip-Seq_HEART_Mouse | 0.95743237 |
127 | * EGR1_20690147_ChIP-Seq_ERYTHROLEUKEMIA_Human | 0.95119418 |
128 | TP53_16413492_ChIP-PET_HCT116_Human | 0.94016759 |
129 | SOX2_20726797_ChIP-Seq_SW620_Human | 0.93887494 |
130 | NANOG_16518401_ChIP-PET_MESCs_Mouse | 0.93398016 |
131 | NANOG_16153702_ChIP-ChIP_HESCs_Human | 0.92392288 |
132 | TCF3_18692474_ChIP-Seq_MESCs_Mouse | 0.92160267 |
133 | ARNT_22903824_ChIP-Seq_MCF-7_Human | 0.91939975 |
134 | RCOR1_19997604_ChIP-ChIP_NEURONS_Mouse | 0.91476791 |
135 | * NELFA_20434984_ChIP-Seq_ESCs_Mouse | 0.91333525 |
Rank | Gene Set | Z-score |
---|---|---|
1 | MP0003705_abnormal_hypodermis_morpholog | 4.36171911 |
2 | MP0005171_absent_coat_pigmentation | 3.12743213 |
3 | MP0004272_abnormal_basement_membrane | 3.11624992 |
4 | MP0009053_abnormal_anal_canal | 2.67346534 |
5 | MP0010352_gastrointestinal_tract_polyps | 2.63527356 |
6 | * MP0000537_abnormal_urethra_morphology | 2.60962689 |
7 | MP0005623_abnormal_meninges_morphology | 2.48302513 |
8 | MP0005076_abnormal_cell_differentiation | 2.39810161 |
9 | MP0003283_abnormal_digestive_organ | 2.39756994 |
10 | MP0003123_paternal_imprinting | 2.33215130 |
11 | MP0010030_abnormal_orbit_morphology | 2.33182007 |
12 | MP0008438_abnormal_cutaneous_collagen | 2.22376478 |
13 | MP0010368_abnormal_lymphatic_system | 2.11418942 |
14 | MP0003122_maternal_imprinting | 2.09131667 |
15 | MP0005409_darkened_coat_color | 2.03646775 |
16 | MP0005275_abnormal_skin_tensile | 1.96995693 |
17 | MP0005408_hypopigmentation | 1.90589805 |
18 | MP0003385_abnormal_body_wall | 1.85972279 |
19 | MP0003566_abnormal_cell_adhesion | 1.84546260 |
20 | MP0003121_genomic_imprinting | 1.82246956 |
21 | MP0000534_abnormal_ureter_morphology | 1.74993842 |
22 | MP0003136_yellow_coat_color | 1.74283003 |
23 | MP0001958_emphysema | 1.73224408 |
24 | MP0001879_abnormal_lymphatic_vessel | 1.73150923 |
25 | MP0000579_abnormal_nail_morphology | 1.71987368 |
26 | MP0002009_preneoplasia | 1.70432487 |
27 | MP0003567_abnormal_fetal_cardiomyocyte | 1.66287367 |
28 | MP0002877_abnormal_melanocyte_morpholog | 1.64402015 |
29 | MP0000428_abnormal_craniofacial_morphol | 1.64063925 |
30 | MP0003942_abnormal_urinary_system | 1.61690978 |
31 | MP0002234_abnormal_pharynx_morphology | 1.60337450 |
32 | * MP0003115_abnormal_respiratory_system | 1.60186786 |
33 | MP0004197_abnormal_fetal_growth/weight/ | 1.58042606 |
34 | MP0000569_abnormal_digit_pigmentation | 1.55322269 |
35 | MP0003300_gastrointestinal_ulcer | 1.53501791 |
36 | MP0005503_abnormal_tendon_morphology | 1.52584413 |
37 | * MP0002084_abnormal_developmental_patter | 1.50359532 |
38 | * MP0000733_abnormal_muscle_development | 1.48273657 |
39 | * MP0003119_abnormal_digestive_system | 1.48215978 |
40 | MP0005197_abnormal_uvea_morphology | 1.45605248 |
41 | * MP0003935_abnormal_craniofacial_develop | 1.44047673 |
42 | * MP0010234_abnormal_vibrissa_follicle | 1.43876194 |
43 | MP0000566_synostosis | 1.40213665 |
44 | MP0000516_abnormal_urinary_system | 1.37927297 |
45 | MP0005367_renal/urinary_system_phenotyp | 1.37927297 |
46 | MP0003941_abnormal_skin_development | 1.36789209 |
47 | * MP0002086_abnormal_extraembryonic_tissu | 1.32085628 |
48 | MP0003453_abnormal_keratinocyte_physiol | 1.31495947 |
49 | * MP0001849_ear_inflammation | 1.30885522 |
50 | MP0003890_abnormal_embryonic-extraembry | 1.29540983 |
51 | MP0009780_abnormal_chondrocyte_physiolo | 1.29400706 |
52 | * MP0002896_abnormal_bone_mineralization | 1.28421475 |
53 | * MP0002925_abnormal_cardiovascular_devel | 1.28199456 |
54 | * MP0003937_abnormal_limbs/digits/tail_de | 1.28124831 |
55 | MP0009384_cardiac_valve_regurgitation | 1.27533419 |
56 | * MP0002085_abnormal_embryonic_tissue | 1.27133154 |
57 | MP0004264_abnormal_extraembryonic_tissu | 1.27081609 |
58 | MP0001730_embryonic_growth_arrest | 1.25443121 |
59 | * MP0005187_abnormal_penis_morphology | 1.24145899 |
60 | MP0003091_abnormal_cell_migration | 1.23028522 |
61 | MP0002233_abnormal_nose_morphology | 1.21824366 |
62 | MP0005257_abnormal_intraocular_pressure | 1.21461680 |
63 | MP0000372_irregular_coat_pigmentation | 1.21307165 |
64 | MP0004858_abnormal_nervous_system | 1.20416439 |
65 | MP0003279_aneurysm | 1.15964030 |
66 | MP0009278_abnormal_bone_marrow | 1.15149110 |
67 | MP0002254_reproductive_system_inflammat | 1.14984675 |
68 | * MP0005380_embryogenesis_phenotype | 1.14155091 |
69 | * MP0001672_abnormal_embryogenesis/_devel | 1.14155091 |
70 | * MP0003755_abnormal_palate_morphology | 1.14153482 |
71 | MP0001293_anophthalmia | 1.13803758 |
72 | * MP0002088_abnormal_embryonic_growth/wei | 1.13164721 |
73 | * MP0003984_embryonic_growth_retardation | 1.12704255 |
74 | MP0001299_abnormal_eye_distance/ | 1.12677070 |
75 | MP0004233_abnormal_muscle_weight | 1.12308331 |
76 | MP0008932_abnormal_embryonic_tissue | 1.12099762 |
77 | * MP0002060_abnormal_skin_morphology | 1.11213592 |
78 | * MP0010678_abnormal_skin_adnexa | 1.09450356 |
79 | MP0004084_abnormal_cardiac_muscle | 1.08926211 |
80 | MP0000767_abnormal_smooth_muscle | 1.08619344 |
81 | MP0009250_abnormal_appendicular_skeleto | 1.08347307 |
82 | * MP0002697_abnormal_eye_size | 1.06937531 |
83 | MP0010307_abnormal_tumor_latency | 1.06753560 |
84 | MP0000383_abnormal_hair_follicle | 1.06532569 |
85 | MP0005508_abnormal_skeleton_morphology | 1.06257344 |
86 | * MP0000377_abnormal_hair_follicle | 1.05221769 |
87 | MP0000462_abnormal_digestive_system | 1.04937223 |
88 | * MP0001697_abnormal_embryo_size | 1.04647224 |
89 | * MP0002932_abnormal_joint_morphology | 1.04314398 |
90 | MP0004185_abnormal_adipocyte_glucose | 1.03906976 |
91 | * MP0000432_abnormal_head_morphology | 1.02799915 |
92 | * MP0005248_abnormal_Harderian_gland | 1.00411869 |
93 | * MP0002116_abnormal_craniofacial_bone | 0.98318853 |
94 | MP0000013_abnormal_adipose_tissue | 0.98081361 |
95 | * MP0002282_abnormal_trachea_morphology | 0.98052607 |
96 | * MP0002092_abnormal_eye_morphology | 0.97923830 |
97 | MP0002249_abnormal_larynx_morphology | 0.97805958 |
98 | MP0005023_abnormal_wound_healing | 0.97652242 |
99 | MP0009703_decreased_birth_body | 0.96966628 |
100 | MP0008961_abnormal_basal_metabolism | 0.95693853 |
101 | MP0010630_abnormal_cardiac_muscle | 0.95535437 |
102 | MP0000762_abnormal_tongue_morphology | 0.95472594 |
103 | MP0000049_abnormal_middle_ear | 0.94714033 |
104 | MP0009672_abnormal_birth_weight | 0.93455641 |
105 | MP0003950_abnormal_plasma_membrane | 0.92605033 |
106 | MP0000371_diluted_coat_color | 0.92477755 |
107 | * MP0003861_abnormal_nervous_system | 0.91431787 |
108 | MP0004782_abnormal_surfactant_physiolog | 0.90872046 |
109 | MP0006138_congestive_heart_failure | 0.89810535 |
110 | MP0002938_white_spotting | 0.89455468 |
111 | MP0001286_abnormal_eye_development | 0.89431571 |
112 | MP0000751_myopathy | 0.87706765 |
113 | * MP0000266_abnormal_heart_morphology | 0.87318496 |
114 | MP0002089_abnormal_postnatal_growth/wei | 0.86802004 |
115 | MP0001661_extended_life_span | 0.86532907 |
116 | MP0000350_abnormal_cell_proliferation | 0.85376555 |
117 | * MP0002080_prenatal_lethality | 0.84455016 |
118 | * MP0002111_abnormal_tail_morphology | 0.84229989 |
119 | MP0002075_abnormal_coat/hair_pigmentati | 0.84156647 |
120 | * MP0001915_intracranial_hemorrhage | 0.84079936 |
121 | * MP0001614_abnormal_blood_vessel | 0.83992201 |
122 | MP0004270_analgesia | 0.83050709 |
123 | MP0000467_abnormal_esophagus_morphology | 0.82432407 |
124 | MP0001186_pigmentation_phenotype | 0.82096822 |
125 | MP0000003_abnormal_adipose_tissue | 0.81309526 |
126 | * MP0002128_abnormal_blood_circulation | 0.79986819 |
127 | * MP0005193_abnormal_anterior_eye | 0.78890122 |
128 | * MP0000647_abnormal_sebaceous_gland | 0.77872176 |
129 | MP0002177_abnormal_outer_ear | 0.77449911 |
130 | MP0002796_impaired_skin_barrier | 0.77438321 |
131 | * MP0002098_abnormal_vibrissa_morphology | 0.75134615 |
132 | MP0001177_atelectasis | 0.74408146 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Shallow orbits (HP:0000586) | 3.65627435 |
2 | Short 4th metacarpal (HP:0010044) | 3.49813610 |
3 | Aplasia/Hypoplasia of the 4th metacarpal (HP:0010042) | 3.49813610 |
4 | Protrusio acetabuli (HP:0003179) | 3.14048260 |
5 | Cerebral aneurysm (HP:0004944) | 3.13756330 |
6 | Renal duplication (HP:0000075) | 3.02950816 |
7 | Abnormality of the 4th metacarpal (HP:0010012) | 3.01577068 |
8 | Hyperacusis (HP:0010780) | 2.91832735 |
9 | Rectal prolapse (HP:0002035) | 2.72312945 |
10 | Lymphangioma (HP:0100764) | 2.70764195 |
11 | Ankle contracture (HP:0006466) | 2.64033398 |
12 | Bladder diverticulum (HP:0000015) | 2.63095915 |
13 | Hypopigmentation of the fundus (HP:0007894) | 2.55257750 |
14 | Osteolytic defects of the hand bones (HP:0009699) | 2.54586186 |
15 | Osteolytic defects of the phalanges of the hand (HP:0009771) | 2.54586186 |
16 | Enlarged penis (HP:0000040) | 2.46942094 |
17 | Elfin facies (HP:0004428) | 2.45961294 |
18 | Aortic aneurysm (HP:0004942) | 2.44251039 |
19 | Renovascular hypertension (HP:0100817) | 2.43452024 |
20 | Atrophic scars (HP:0001075) | 2.38947578 |
21 | Broad metatarsal (HP:0001783) | 2.35874008 |
22 | Insidious onset (HP:0003587) | 2.35750939 |
23 | Bowel diverticulosis (HP:0005222) | 2.33654737 |
24 | Aplasia involving bones of the extremities (HP:0009825) | 2.33327115 |
25 | Aplasia involving bones of the upper limbs (HP:0009823) | 2.33327115 |
26 | Aplasia of the phalanges of the hand (HP:0009802) | 2.33327115 |
27 | Asymmetry of the thorax (HP:0001555) | 2.30504342 |
28 | Blue irides (HP:0000635) | 2.30259312 |
29 | Deviation of the hallux (HP:0010051) | 2.29773179 |
30 | White forelock (HP:0002211) | 2.29577700 |
31 | Overriding aorta (HP:0002623) | 2.27575600 |
32 | Mitral valve prolapse (HP:0001634) | 2.26295427 |
33 | Premature rupture of membranes (HP:0001788) | 2.24100533 |
34 | Hematochezia (HP:0002573) | 2.23035247 |
35 | Natal tooth (HP:0000695) | 2.22408145 |
36 | Hypoplasia of the iris (HP:0007676) | 2.21191737 |
37 | Buphthalmos (HP:0000557) | 2.20552108 |
38 | Hallux valgus (HP:0001822) | 2.20222005 |
39 | Absent frontal sinuses (HP:0002688) | 2.16905660 |
40 | Vertebral arch anomaly (HP:0008438) | 2.14051948 |
41 | Increased nuchal translucency (HP:0010880) | 2.13721001 |
42 | Flat acetabular roof (HP:0003180) | 2.12326788 |
43 | Pterygium (HP:0001059) | 2.11202434 |
44 | Aneurysm (HP:0002617) | 2.09746414 |
45 | Ankyloglossia (HP:0010296) | 2.09576187 |
46 | Vascular tortuosity (HP:0004948) | 2.08367965 |
47 | Papillary thyroid carcinoma (HP:0002895) | 2.08163509 |
48 | Macroorchidism (HP:0000053) | 2.07202027 |
49 | Arterial tortuosity (HP:0005116) | 2.06504010 |
50 | Cutaneous finger syndactyly (HP:0010554) | 2.06353104 |
51 | Vitreoretinal degeneration (HP:0000655) | 2.06275077 |
52 | Short nail (HP:0001799) | 2.04593014 |
53 | Exostoses (HP:0100777) | 2.04452873 |
54 | Patchy hypopigmentation of hair (HP:0011365) | 2.04309975 |
55 | Abnormality of the distal phalanges of the toes (HP:0010182) | 2.02373836 |
56 | Advanced eruption of teeth (HP:0006288) | 2.02192154 |
57 | Hepatoblastoma (HP:0002884) | 2.00427845 |
58 | Dilatation of the ascending aorta (HP:0005111) | 1.98604039 |
59 | Broad thumb (HP:0011304) | 1.97511145 |
60 | Flat cornea (HP:0007720) | 1.97383510 |
61 | Heterochromia iridis (HP:0001100) | 1.97311987 |
62 | Deviation of the thumb (HP:0009603) | 1.97109715 |
63 | Cutaneous syndactyly (HP:0012725) | 1.96713815 |
64 | Aortic dissection (HP:0002647) | 1.95774195 |
65 | Bronchomalacia (HP:0002780) | 1.93907762 |
66 | Abnormality of the astrocytes (HP:0100707) | 1.93902917 |
67 | Astrocytoma (HP:0009592) | 1.93902917 |
68 | Pointed chin (HP:0000307) | 1.92761411 |
69 | * Subacute progressive viral hepatitis (HP:0006572) | 1.92024868 |
70 | Vertebral clefting (HP:0008428) | 1.91913011 |
71 | Tetraparesis (HP:0002273) | 1.91780902 |
72 | Skull defect (HP:0001362) | 1.90160830 |
73 | Large earlobe (HP:0009748) | 1.89875926 |
74 | Milia (HP:0001056) | 1.88934314 |
75 | Abnormal auditory evoked potentials (HP:0006958) | 1.87875508 |
76 | Insomnia (HP:0100785) | 1.87564986 |
77 | Right ventricular cardiomyopathy (HP:0011663) | 1.86574263 |
78 | Biliary tract neoplasm (HP:0100574) | 1.84745577 |
79 | Colon cancer (HP:0003003) | 1.83928238 |
80 | Proximal placement of thumb (HP:0009623) | 1.82988275 |
81 | Absent eyelashes (HP:0000561) | 1.81985797 |
82 | Abnormality of the distal phalanx of the thumb (HP:0009617) | 1.81761547 |
83 | Turricephaly (HP:0000262) | 1.81321147 |
84 | Ulnar bowing (HP:0003031) | 1.81119008 |
85 | Absent eyebrow (HP:0002223) | 1.81019843 |
86 | Abnormality of the diencephalon (HP:0010662) | 1.79828356 |
87 | Wormian bones (HP:0002645) | 1.79652735 |
88 | Thin bony cortex (HP:0002753) | 1.78544373 |
89 | Abnormality of oral frenula (HP:0000190) | 1.78431257 |
90 | Coronal craniosynostosis (HP:0004440) | 1.77273749 |
91 | Curly hair (HP:0002212) | 1.77187534 |
92 | Mitral stenosis (HP:0001718) | 1.77037553 |
93 | Aplasia/Hypoplasia of the vertebrae (HP:0008515) | 1.74875516 |
94 | Vertebral hypoplasia (HP:0008417) | 1.74875516 |
95 | Fibrous tissue neoplasm (HP:0012316) | 1.74194754 |
96 | Overgrowth (HP:0001548) | 1.74124127 |
97 | Wrist flexion contracture (HP:0001239) | 1.72705049 |
98 | Fibroma (HP:0010614) | 1.72541625 |
99 | Striae distensae (HP:0001065) | 1.72153942 |
100 | Genu recurvatum (HP:0002816) | 1.72038758 |
101 | Radial bowing (HP:0002986) | 1.71807480 |
102 | Short 1st metacarpal (HP:0010034) | 1.70804769 |
103 | Aplasia/Hypoplasia of the 1st metacarpal (HP:0010026) | 1.70804769 |
104 | * Malignant gastrointestinal tract tumors (HP:0006749) | 1.70114842 |
105 | * Gastrointestinal carcinoma (HP:0002672) | 1.70114842 |
106 | Scapular winging (HP:0003691) | 1.70087520 |
107 | Hypoplastic labia majora (HP:0000059) | 1.69575352 |
108 | Hand muscle atrophy (HP:0009130) | 1.68880010 |
109 | High anterior hairline (HP:0009890) | 1.68222286 |
110 | Ependymoma (HP:0002888) | 1.67498809 |
111 | Short humerus (HP:0005792) | 1.67366537 |
112 | Cervical subluxation (HP:0003308) | 1.65999180 |
113 | Short phalanx of the thumb (HP:0009660) | 1.65948585 |
114 | Visceral angiomatosis (HP:0100761) | 1.65931287 |
115 | Omphalocele (HP:0001539) | 1.65813343 |
116 | Obsessive-compulsive behavior (HP:0000722) | 1.65159840 |
117 | Hemangiomatosis (HP:0007461) | 1.64661623 |
118 | Abnormality of dentin (HP:0010299) | 1.64594316 |
119 | Aplasia/Hypoplasia of the frontal sinuses (HP:0009119) | 1.64551580 |
120 | Wide anterior fontanel (HP:0000260) | 1.64452402 |
121 | Freckling (HP:0001480) | 1.63962504 |
122 | Thick nail (HP:0001805) | 1.63567092 |
123 | Neonatal short-limb short stature (HP:0008921) | 1.63552342 |
124 | Back pain (HP:0003418) | 1.63487092 |
125 | Broad phalanges of the hand (HP:0009768) | 1.63331072 |
126 | Cortical dysplasia (HP:0002539) | 1.62702805 |
127 | Arnold-Chiari malformation (HP:0002308) | 1.61900436 |
128 | Esophageal atresia (HP:0002032) | 1.61795332 |
129 | Decreased number of large peripheral myelinated nerve fibers (HP:0003387) | 1.61512863 |
130 | Aplasia/hypoplasia of the humerus (HP:0006507) | 1.58588112 |
131 | Aplasia/Hypoplasia of the pubic bone (HP:0009104) | 1.58250215 |
132 | Distal upper limb amyotrophy (HP:0007149) | 1.58008326 |
133 | Upper limb amyotrophy (HP:0009129) | 1.58008326 |
134 | Scanning speech (HP:0002168) | 1.57481243 |
135 | Broad long bones (HP:0005622) | 1.57452190 |
136 | Broad finger (HP:0001500) | 1.57099954 |
137 | Fragile skin (HP:0001030) | 1.57055521 |
138 | Volvulus (HP:0002580) | 1.57017031 |
139 | Broad ribs (HP:0000885) | 1.56087030 |
140 | Morphological abnormality of the middle ear (HP:0008609) | 1.55878443 |
141 | Missing ribs (HP:0000921) | 1.55753648 |
142 | Vertebral compression fractures (HP:0002953) | 1.55674227 |
143 | Abnormality of the calcaneus (HP:0008364) | 1.55303051 |
144 | Selective tooth agenesis (HP:0001592) | 1.55235666 |
145 | Broad phalanx (HP:0006009) | 1.54298651 |
146 | Long toe (HP:0010511) | 1.53879984 |
147 | Abnormality of the 1st metacarpal (HP:0010009) | 1.53538551 |
148 | Termporal pattern (HP:0011008) | 1.53289968 |
149 | Thyroid carcinoma (HP:0002890) | 1.52625729 |
150 | Neurofibrillary tangles (HP:0002185) | 1.52093024 |
151 | Tracheal stenosis (HP:0002777) | 1.51762093 |
152 | Midface retrusion (HP:0011800) | 1.50994839 |
153 | Deep philtrum (HP:0002002) | 1.50655157 |
154 | Abnormality of the hip-girdle musculature (HP:0001445) | 1.50468929 |
155 | Abnormality of the musculature of the pelvis (HP:0001469) | 1.50468929 |
156 | Aplasia/Hypoplasia of the macula (HP:0008059) | 1.49979254 |
157 | Shoulder girdle muscle weakness (HP:0003547) | 1.49975590 |
158 | Rhizomelia (HP:0008905) | 1.48418476 |
159 | Relative macrocephaly (HP:0004482) | 1.47210364 |
160 | Hammertoe (HP:0001765) | 1.47046680 |
161 | Thin ribs (HP:0000883) | 1.45884296 |
162 | Aplasia/Hypoplasia involving the sinuses (HP:0009120) | 1.45098556 |
163 | Cerebral inclusion bodies (HP:0100314) | 1.44863515 |
164 | Broad face (HP:0000283) | 1.42648676 |
165 | Alacrima (HP:0000522) | 1.42590323 |
Rank | Gene Set | Z-score |
---|---|---|
1 | TRIB3 | 3.91136882 |
2 | PKN2 | 3.68262557 |
3 | LATS1 | 3.22129064 |
4 | RIPK1 | 2.96398220 |
5 | PDGFRA | 2.79241934 |
6 | BCR | 2.70076666 |
7 | EPHB2 | 2.54769730 |
8 | EEF2K | 2.27300937 |
9 | DDR2 | 2.25759705 |
10 | SCYL2 | 2.21533445 |
11 | MAP3K10 | 2.20676525 |
12 | SRPK1 | 2.16711082 |
13 | TTN | 2.10294526 |
14 | NEK1 | 2.01029677 |
15 | EPHA2 | 1.85693167 |
16 | LATS2 | 1.84056876 |
17 | TIE1 | 1.78750661 |
18 | CDK12 | 1.76010204 |
19 | TGFBR1 | 1.63320063 |
20 | PLK2 | 1.55514594 |
21 | SMG1 | 1.55047412 |
22 | * PTK6 | 1.54837127 |
23 | LMTK2 | 1.53733990 |
24 | KSR1 | 1.49373547 |
25 | WEE1 | 1.49337577 |
26 | PTK2 | 1.48466494 |
27 | TYRO3 | 1.46368296 |
28 | LRRK2 | 1.45846031 |
29 | FGFR2 | 1.44494296 |
30 | PRKD3 | 1.43991982 |
31 | KSR2 | 1.43868141 |
32 | MKNK2 | 1.41263468 |
33 | MET | 1.38741479 |
34 | STK24 | 1.36343061 |
35 | FGFR1 | 1.34403451 |
36 | TRIM28 | 1.32176829 |
37 | MAP3K2 | 1.32012806 |
38 | PASK | 1.31350279 |
39 | ERBB4 | 1.26761259 |
40 | SIK1 | 1.26681068 |
41 | ERBB3 | 1.24092624 |
42 | STK3 | 1.23308245 |
43 | PDGFRB | 1.21947044 |
44 | BMX | 1.21135354 |
45 | RET | 1.19708176 |
46 | MTOR | 1.18740437 |
47 | RPS6KB2 | 1.18596470 |
48 | FRK | 1.16929842 |
49 | ICK | 1.14362090 |
50 | TSSK6 | 1.13774981 |
51 | ALK | 1.12595088 |
52 | PAK2 | 1.12218431 |
53 | NEK2 | 1.08473644 |
54 | MAP3K9 | 1.03590534 |
55 | PBK | 1.01908844 |
56 | CDC7 | 1.00327884 |
57 | DMPK | 0.97181382 |
58 | PAK3 | 0.94871776 |
59 | TGFBR2 | 0.94849811 |
60 | MST1R | 0.94459133 |
61 | STK39 | 0.91719186 |
62 | CAMK1D | 0.90815135 |
63 | MOS | 0.89792694 |
64 | CAMK1G | 0.86996091 |
65 | MAP3K8 | 0.84274708 |
66 | EPHA4 | 0.83805518 |
67 | TAF1 | 0.83691159 |
68 | EIF2AK3 | 0.83074005 |
69 | AKT3 | 0.82274934 |
70 | DYRK1B | 0.79614509 |
71 | CAMKK1 | 0.78848045 |
72 | CASK | 0.78537110 |
73 | PAK6 | 0.77697427 |
74 | MST4 | 0.75305245 |
75 | TNIK | 0.73801082 |
76 | TESK1 | 0.73640284 |
77 | SIK3 | 0.72858223 |
78 | STK38L | 0.72118445 |
79 | ILK | 0.71971670 |
80 | FGFR3 | 0.71613183 |
81 | EPHB1 | 0.66498637 |
82 | BRSK2 | 0.66456781 |
83 | KDR | 0.66327215 |
84 | STK10 | 0.66075441 |
85 | NTRK1 | 0.64627650 |
86 | MAP2K1 | 0.62921558 |
87 | NEK6 | 0.61492766 |
88 | CDK18 | 0.60700358 |
89 | MELK | 0.60601200 |
90 | RPS6KA4 | 0.57485274 |
91 | * FER | 0.57042092 |
92 | ROCK1 | 0.56183106 |
93 | YES1 | 0.55355171 |
94 | MAP2K2 | 0.53882959 |
95 | MAP2K7 | 0.52944600 |
96 | MAP3K4 | 0.52494985 |
97 | CDK14 | 0.51239190 |
98 | TTK | 0.49447221 |
99 | CDK15 | 0.49355580 |
100 | BRD4 | 0.49254734 |
101 | EPHA3 | 0.48384606 |
102 | CDC42BPA | 0.47150903 |
103 | CDK7 | 0.46651399 |
104 | MARK1 | 0.46479065 |
105 | PTK2B | 0.45074931 |
106 | PRKCH | 0.44791024 |
107 | * PAK4 | 0.43579076 |
108 | STK38 | 0.43362455 |
109 | RPS6KA2 | 0.42732876 |
110 | LIMK1 | 0.40867938 |
111 | * SRC | 0.40850826 |
112 | MKNK1 | 0.40415356 |
113 | NTRK2 | 0.38863545 |
114 | CDK11A | 0.38837713 |
115 | ERN1 | 0.38050015 |
116 | PLK3 | 0.37735140 |
117 | CDK4 | 0.37342817 |
118 | TAOK1 | 0.37092272 |
119 | MAPK10 | 0.36832755 |
120 | MAP3K7 | 0.36744552 |
121 | * ERBB2 | 0.36317272 |
122 | AURKB | 0.36069502 |
123 | FGFR4 | 0.35842068 |
124 | IRAK3 | 0.35586338 |
125 | MAP3K6 | 0.35186243 |
126 | RPS6KB1 | 0.33606016 |
127 | PRKCE | 0.33585060 |
128 | PRKDC | 0.32996196 |
129 | FLT3 | 0.32807781 |
130 | ROCK2 | 0.32551325 |
131 | CHEK1 | 0.32477031 |
132 | EIF2AK2 | 0.32410402 |
133 | WNK3 | 0.32178877 |
134 | PRKG2 | 0.31908595 |
135 | MINK1 | 0.31768556 |
136 | NEK9 | 0.31318895 |
137 | INSR | 0.31313770 |
138 | NLK | 0.31188764 |
139 | RPS6KA1 | 0.30675394 |
140 | CDK9 | 0.29603305 |
Rank | Gene Set | Z-score |
---|---|---|
1 | Steroid biosynthesis_Homo sapiens_hsa00100 | 2.31711546 |
2 | * Adherens junction_Homo sapiens_hsa04520 | 2.26174725 |
3 | * Hippo signaling pathway_Homo sapiens_hsa04390 | 2.16589421 |
4 | ECM-receptor interaction_Homo sapiens_hsa04512 | 2.14776646 |
5 | * Focal adhesion_Homo sapiens_hsa04510 | 1.97352736 |
6 | * Proteoglycans in cancer_Homo sapiens_hsa05205 | 1.89812722 |
7 | * Basal cell carcinoma_Homo sapiens_hsa05217 | 1.84700439 |
8 | Small cell lung cancer_Homo sapiens_hsa05222 | 1.77105962 |
9 | Chronic myeloid leukemia_Homo sapiens_hsa05220 | 1.72201987 |
10 | MicroRNAs in cancer_Homo sapiens_hsa05206 | 1.70252676 |
11 | * Bacterial invasion of epithelial cells_Homo sapiens_hsa05100 | 1.69801392 |
12 | * Tight junction_Homo sapiens_hsa04530 | 1.66523551 |
13 | Hedgehog signaling pathway_Homo sapiens_hsa04340 | 1.65748744 |
14 | TGF-beta signaling pathway_Homo sapiens_hsa04350 | 1.62321339 |
15 | * Signaling pathways regulating pluripotency of stem cells_Homo sapiens_hsa04550 | 1.53283746 |
16 | mTOR signaling pathway_Homo sapiens_hsa04150 | 1.51977256 |
17 | Biosynthesis of unsaturated fatty acids_Homo sapiens_hsa01040 | 1.51354002 |
18 | Vitamin B6 metabolism_Homo sapiens_hsa00750 | 1.47141977 |
19 | Bladder cancer_Homo sapiens_hsa05219 | 1.46432137 |
20 | Citrate cycle (TCA cycle)_Homo sapiens_hsa00020 | 1.45453241 |
21 | * Endometrial cancer_Homo sapiens_hsa05213 | 1.45416856 |
22 | Butirosin and neomycin biosynthesis_Homo sapiens_hsa00524 | 1.43563277 |
23 | Glioma_Homo sapiens_hsa05214 | 1.42374263 |
24 | Axon guidance_Homo sapiens_hsa04360 | 1.39262653 |
25 | Central carbon metabolism in cancer_Homo sapiens_hsa05230 | 1.37119092 |
26 | Nitrogen metabolism_Homo sapiens_hsa00910 | 1.36777203 |
27 | Biosynthesis of amino acids_Homo sapiens_hsa01230 | 1.34626378 |
28 | Terpenoid backbone biosynthesis_Homo sapiens_hsa00900 | 1.34509708 |
29 | Estrogen signaling pathway_Homo sapiens_hsa04915 | 1.32557314 |
30 | Amoebiasis_Homo sapiens_hsa05146 | 1.31248393 |
31 | * Arrhythmogenic right ventricular cardiomyopathy (ARVC)_Homo sapiens_hsa05412 | 1.30786654 |
32 | Progesterone-mediated oocyte maturation_Homo sapiens_hsa04914 | 1.28996714 |
33 | Dorso-ventral axis formation_Homo sapiens_hsa04320 | 1.28995881 |
34 | * Colorectal cancer_Homo sapiens_hsa05210 | 1.28247949 |
35 | Aldosterone-regulated sodium reabsorption_Homo sapiens_hsa04960 | 1.27421190 |
36 | Renal cell carcinoma_Homo sapiens_hsa05211 | 1.27038140 |
37 | AGE-RAGE signaling pathway in diabetic complications_Homo sapiens_hsa04933 | 1.25406401 |
38 | Protein digestion and absorption_Homo sapiens_hsa04974 | 1.25392482 |
39 | Glycosaminoglycan degradation_Homo sapiens_hsa00531 | 1.21301511 |
40 | Glycosaminoglycan biosynthesis - heparan sulfate / heparin_Homo sapiens_hsa00534 | 1.20701392 |
41 | * Melanogenesis_Homo sapiens_hsa04916 | 1.20127859 |
42 | Gap junction_Homo sapiens_hsa04540 | 1.19634523 |
43 | Notch signaling pathway_Homo sapiens_hsa04330 | 1.16389841 |
44 | Glycolysis / Gluconeogenesis_Homo sapiens_hsa00010 | 1.16329782 |
45 | Endocrine and other factor-regulated calcium reabsorption_Homo sapiens_hsa04961 | 1.15691110 |
46 | Other glycan degradation_Homo sapiens_hsa00511 | 1.15291930 |
47 | Pancreatic cancer_Homo sapiens_hsa05212 | 1.14184699 |
48 | Dilated cardiomyopathy_Homo sapiens_hsa05414 | 1.14152630 |
49 | * Wnt signaling pathway_Homo sapiens_hsa04310 | 1.13584486 |
50 | * Thyroid hormone signaling pathway_Homo sapiens_hsa04919 | 1.10652183 |
51 | Non-small cell lung cancer_Homo sapiens_hsa05223 | 1.10373679 |
52 | Viral myocarditis_Homo sapiens_hsa05416 | 1.07525479 |
53 | * Leukocyte transendothelial migration_Homo sapiens_hsa04670 | 1.06957224 |
54 | VEGF signaling pathway_Homo sapiens_hsa04370 | 1.06261041 |
55 | Vibrio cholerae infection_Homo sapiens_hsa05110 | 1.05949813 |
56 | Neurotrophin signaling pathway_Homo sapiens_hsa04722 | 1.04242134 |
57 | Oocyte meiosis_Homo sapiens_hsa04114 | 1.04177990 |
58 | * Rap1 signaling pathway_Homo sapiens_hsa04015 | 1.02991789 |
59 | Pentose phosphate pathway_Homo sapiens_hsa00030 | 1.02840406 |
60 | * Pathways in cancer_Homo sapiens_hsa05200 | 1.02710372 |
61 | Vasopressin-regulated water reabsorption_Homo sapiens_hsa04962 | 1.02495442 |
62 | 2-Oxocarboxylic acid metabolism_Homo sapiens_hsa01210 | 0.99939041 |
63 | Carbon metabolism_Homo sapiens_hsa01200 | 0.97207046 |
64 | Insulin resistance_Homo sapiens_hsa04931 | 0.97183833 |
65 | Melanoma_Homo sapiens_hsa05218 | 0.93475850 |
66 | Lysine degradation_Homo sapiens_hsa00310 | 0.92141994 |
67 | Regulation of actin cytoskeleton_Homo sapiens_hsa04810 | 0.91384566 |
68 | Non-homologous end-joining_Homo sapiens_hsa03450 | 0.91120160 |
69 | Regulation of lipolysis in adipocytes_Homo sapiens_hsa04923 | 0.90594859 |
70 | Hypertrophic cardiomyopathy (HCM)_Homo sapiens_hsa05410 | 0.90542532 |
71 | Longevity regulating pathway - multiple species_Homo sapiens_hsa04213 | 0.89996004 |
72 | PI3K-Akt signaling pathway_Homo sapiens_hsa04151 | 0.88901596 |
73 | Ubiquitin mediated proteolysis_Homo sapiens_hsa04120 | 0.88602563 |
74 | Sphingolipid metabolism_Homo sapiens_hsa00600 | 0.88413998 |
75 | * Prostate cancer_Homo sapiens_hsa05215 | 0.87649471 |
76 | Aminoacyl-tRNA biosynthesis_Homo sapiens_hsa00970 | 0.86718004 |
77 | Adrenergic signaling in cardiomyocytes_Homo sapiens_hsa04261 | 0.84840408 |
78 | Platelet activation_Homo sapiens_hsa04611 | 0.84553201 |
79 | AMPK signaling pathway_Homo sapiens_hsa04152 | 0.82702582 |
80 | * HTLV-I infection_Homo sapiens_hsa05166 | 0.82334363 |
81 | Type II diabetes mellitus_Homo sapiens_hsa04930 | 0.82276592 |
82 | Viral carcinogenesis_Homo sapiens_hsa05203 | 0.82152308 |
83 | p53 signaling pathway_Homo sapiens_hsa04115 | 0.80896222 |
84 | Protein processing in endoplasmic reticulum_Homo sapiens_hsa04141 | 0.80438603 |
85 | Thyroid hormone synthesis_Homo sapiens_hsa04918 | 0.80093357 |
86 | Longevity regulating pathway - mammal_Homo sapiens_hsa04211 | 0.79538642 |
87 | Galactose metabolism_Homo sapiens_hsa00052 | 0.79507351 |
88 | Cell cycle_Homo sapiens_hsa04110 | 0.79448863 |
89 | ErbB signaling pathway_Homo sapiens_hsa04012 | 0.78473032 |
90 | Gastric acid secretion_Homo sapiens_hsa04971 | 0.76978463 |
91 | Insulin signaling pathway_Homo sapiens_hsa04910 | 0.76646393 |
92 | cGMP-PKG signaling pathway_Homo sapiens_hsa04022 | 0.76498430 |
93 | GnRH signaling pathway_Homo sapiens_hsa04912 | 0.76369924 |
94 | HIF-1 signaling pathway_Homo sapiens_hsa04066 | 0.74652990 |
95 | Renin-angiotensin system_Homo sapiens_hsa04614 | 0.74614123 |
96 | mRNA surveillance pathway_Homo sapiens_hsa03015 | 0.74441522 |
97 | Toxoplasmosis_Homo sapiens_hsa05145 | 0.73955760 |
98 | Inositol phosphate metabolism_Homo sapiens_hsa00562 | 0.73362580 |
99 | Renin secretion_Homo sapiens_hsa04924 | 0.72976540 |
100 | Arginine biosynthesis_Homo sapiens_hsa00220 | 0.72034831 |
101 | * Thyroid cancer_Homo sapiens_hsa05216 | 0.71544439 |
102 | Fatty acid metabolism_Homo sapiens_hsa01212 | 0.71233218 |
103 | FoxO signaling pathway_Homo sapiens_hsa04068 | 0.70206238 |
104 | Long-term potentiation_Homo sapiens_hsa04720 | 0.68221008 |
105 | Other types of O-glycan biosynthesis_Homo sapiens_hsa00514 | 0.65632974 |
106 | Phospholipase D signaling pathway_Homo sapiens_hsa04072 | 0.65512043 |
107 | Endocytosis_Homo sapiens_hsa04144 | 0.65307726 |
108 | Lysosome_Homo sapiens_hsa04142 | 0.65059106 |
109 | Proximal tubule bicarbonate reclamation_Homo sapiens_hsa04964 | 0.64801470 |
110 | * Pathogenic Escherichia coli infection_Homo sapiens_hsa05130 | 0.64188855 |
111 | Glucagon signaling pathway_Homo sapiens_hsa04922 | 0.64046020 |
112 | Aldosterone synthesis and secretion_Homo sapiens_hsa04925 | 0.64025828 |
113 | Prolactin signaling pathway_Homo sapiens_hsa04917 | 0.63906548 |
114 | Bile secretion_Homo sapiens_hsa04976 | 0.63529071 |
115 | Prion diseases_Homo sapiens_hsa05020 | 0.63228311 |
116 | Salmonella infection_Homo sapiens_hsa05132 | 0.62817734 |
117 | Alcoholism_Homo sapiens_hsa05034 | 0.62128163 |
118 | Carbohydrate digestion and absorption_Homo sapiens_hsa04973 | 0.60698963 |
119 | Oxytocin signaling pathway_Homo sapiens_hsa04921 | 0.59271635 |
120 | Fructose and mannose metabolism_Homo sapiens_hsa00051 | 0.58955529 |
121 | Mucin type O-Glycan biosynthesis_Homo sapiens_hsa00512 | 0.58901852 |
122 | Circadian rhythm_Homo sapiens_hsa04710 | 0.58745400 |
123 | Alanine, aspartate and glutamate metabolism_Homo sapiens_hsa00250 | 0.58537025 |
124 | Shigellosis_Homo sapiens_hsa05131 | 0.58516700 |
125 | Transcriptional misregulation in cancer_Homo sapiens_hsa05202 | 0.57601503 |
126 | Fatty acid elongation_Homo sapiens_hsa00062 | 0.56985010 |
127 | Pyruvate metabolism_Homo sapiens_hsa00620 | 0.56598660 |
128 | Arginine and proline metabolism_Homo sapiens_hsa00330 | 0.56189085 |
129 | Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate_Homo sapiens_hsa00532 | 0.55723000 |
130 | Choline metabolism in cancer_Homo sapiens_hsa05231 | 0.52591515 |
131 | N-Glycan biosynthesis_Homo sapiens_hsa00510 | 0.51778187 |
132 | Mineral absorption_Homo sapiens_hsa04978 | 0.50974513 |
133 | Vascular smooth muscle contraction_Homo sapiens_hsa04270 | 0.49831312 |
134 | Insulin secretion_Homo sapiens_hsa04911 | 0.48663524 |
135 | Amino sugar and nucleotide sugar metabolism_Homo sapiens_hsa00520 | 0.47068042 |
136 | Glycosphingolipid biosynthesis - ganglio series_Homo sapiens_hsa00604 | 0.44144913 |